Development of virus vectors for gene therapy of β chain hemoglobinopathies: Flanking with a chromatin insulator reduces γ-globin gene silencing in vivo

Blood

Volumn 100, Issue 6, 2002, Pages 2012-2019

  Emery, David W ^a,b   Yannaki, Evangelia ^a,b   Tubb, Julie ^a,b   Nishino, Tamon ^a,b   Li, Qiliang ^a,b   Stamatoyannopoulos, George ^a,b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b G PAPANICOLAOU HOSPITAL   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA GLOBIN; VIRUS VECTOR;

ANIMAL CELL; ARTICLE; BONE MARROW TRANSPLANTATION; CHROMATIN; CONTROLLED STUDY; ENHANCER REGION; FLOW CYTOMETRY; GENE CASSETTE; GENE EXPRESSION; GENE SILENCING; GENE THERAPY; GENETIC STABILITY; HEMOGLOBINOPATHY; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SIGNAL TRANSDUCTION; TREATMENT OUTCOME;

EID: 0037105522     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2002-01-0219     Document Type: Article

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