메뉴 건너뛰기




Volumn 88, Issue 10, 1996, Pages 4051-4057

Activation of δ-globin gene expression by erythroid Krupple-like factor: A potential approach for gene therapy of sickle cell disease

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN; DELTA GLOBIN; HEMOGLOBIN A2; MESSENGER RNA; TRANSCRIPTION FACTOR; ZINC FINGER PROTEIN;

EID: 0029850721     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v88.10.4051.bloodjournal88104051     Document Type: Article
Times cited : (30)

References (37)
  • 2
    • 0027985201 scopus 로고
    • Recombinant adeno-associated virus (rAAV)-mediated expression of a human gamma-globin gene in human progenitor-derived erythroid cells
    • Miller JL, Donahue RE, Sellers SE, Samulski RJ, Young NS, Nienhuis AW: Recombinant adeno-associated virus (rAAV)-mediated expression of a human gamma-globin gene in human progenitor-derived erythroid cells. Proc Natl Acad Sci USA 91:10183, 1994
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10183
    • Miller, J.L.1    Donahue, R.E.2    Sellers, S.E.3    Samulski, R.J.4    Young, N.S.5    Nienhuis, A.W.6
  • 3
    • 0029145011 scopus 로고
    • Regulated high-level human beta-globin gene expression in erythroid cells following recombinant adeno-associated virus-mediated gene transfer
    • Einerhand MP, Antoniou M, Zolotukhin S, Muzyczka N, Berns KI, Grosveld F, Valerio D: Regulated high-level human beta-globin gene expression in erythroid cells following recombinant adeno-associated virus-mediated gene transfer. Gene Ther 2:336, 1995
    • (1995) Gene Ther , vol.2 , pp. 336
    • Einerhand, M.P.1    Antoniou, M.2    Zolotukhin, S.3    Muzyczka, N.4    Berns, K.I.5    Grosveld, F.6    Valerio, D.7
  • 4
    • 0028949176 scopus 로고
    • Retroviral transfer of a human beta-globin/delta-globin hybrid gene linked to beta locus control region hypersensitive site 2 aimed at the gene therapy of sickle cell disease
    • Takekoshi KJ, Oh YH, Westerman KW, London IM, Leboulch P: Retroviral transfer of a human beta-globin/delta-globin hybrid gene linked to beta locus control region hypersensitive site 2 aimed at the gene therapy of sickle cell disease. Proc Natl Acad Sci USA 92:3014, 1995
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3014
    • Takekoshi, K.J.1    Oh, Y.H.2    Westerman, K.W.3    London, I.M.4    Leboulch, P.5
  • 5
    • 0025976935 scopus 로고
    • Genetically modified skin fibroblasts persist long after transplantation but gradually inactivate introduced genes
    • Palmer TD, Rosman GJ, Osborne WRA, Miller D: Genetically modified skin fibroblasts persist long after transplantation but gradually inactivate introduced genes. Cell 88:1330, 1991
    • (1991) Cell , vol.88 , pp. 1330
    • Palmer, T.D.1    Rosman, G.J.2    Osborne, W.R.A.3    Miller, D.4
  • 6
    • 0025978973 scopus 로고
    • Gene therapy in perspective
    • Weatherall DJ: Gene therapy in perspective. Nature 349:275, 1991
    • (1991) Nature , vol.349 , pp. 275
    • Weatherall, D.J.1
  • 7
    • 0028062923 scopus 로고
    • Retroviral vector sequences inhibit human beta-globin gene expression in transgenic mice
    • McCune SL, Townes TM: Retroviral vector sequences inhibit human beta-globin gene expression in transgenic mice. Nucleic Acids Res 22:4477, 1994
    • (1994) Nucleic Acids Res , vol.22 , pp. 4477
    • McCune, S.L.1    Townes, T.M.2
  • 9
    • 0025925290 scopus 로고
    • 2: Origin, evolution, and aftermath
    • 2: Origin, evolution, and aftermath. Blood 78:2165, 1991
    • (1991) Blood , vol.78 , pp. 2165
    • Steinberg, M.H.1    Adams, J.G.2
  • 10
    • 0020724929 scopus 로고
    • Three regions upstream from the cap site are required for efficient and accurate transcription of the rabbit β-globin gene in mouse 3T3 cells
    • Dierks PA, van Ooyen A, Cochran MD, Dobkin C, Reiser J, Weissman C: Three regions upstream from the cap site are required for efficient and accurate transcription of the rabbit β-globin gene in mouse 3T3 cells. Cell 32:695, 1983
    • (1983) Cell , vol.32 , pp. 695
    • Dierks, P.A.1    Van Ooyen, A.2    Cochran, M.D.3    Dobkin, C.4    Reiser, J.5    Weissman, C.6
  • 11
    • 0023040149 scopus 로고
    • Fine structure genetic analysis of a β-globin promoter
    • Myers RM, Tilly K, Maniatis T: Fine structure genetic analysis of a β-globin promoter. Science 232:613, 1986
    • (1986) Science , vol.232 , pp. 613
    • Myers, R.M.1    Tilly, K.2    Maniatis, T.3
  • 12
    • 0023807622 scopus 로고
    • DNA sequences involved in transcriptional regulation of the mouse β-globin promoter in murine erythroleukemia cells
    • Cowie A, Myers R: DNA sequences involved in transcriptional regulation of the mouse β-globin promoter in murine erythroleukemia cells. Mol Cell Biol 8:3122, 1988
    • (1988) Mol Cell Biol , vol.8 , pp. 3122
    • Cowie, A.1    Myers, R.2
  • 13
    • 0027211845 scopus 로고
    • A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Kruppel family of nuclear proteins
    • Miller IJ, Bieker JJ: A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Kruppel family of nuclear proteins. Mol Cell Biol 13:2776, 1993
    • (1993) Mol Cell Biol , vol.13 , pp. 2776
    • Miller, I.J.1    Bieker, J.J.2
  • 14
    • 0028936440 scopus 로고
    • Role of the erythroid Kruppel-like factor in human γ to β-globin gene switching
    • Donze D, Townes TM, Bieker JJ: Role of the erythroid Kruppel-like factor in human γ to β-globin gene switching. J Biol Chem 270:1955, 1995
    • (1995) J Biol Chem , vol.270 , pp. 1955
    • Donze, D.1    Townes, T.M.2    Bieker, J.J.3
  • 15
    • 0029010790 scopus 로고
    • Defective haemotopoiesis in fetal liver resulting from inactivation of the EKLF gene
    • Nuez B, Michalovich D, Bygrave A, Ploemacher R, Grosveld F: Defective haemotopoiesis in fetal liver resulting from inactivation of the EKLF gene. Nature 375:316, 1995
    • (1995) Nature , vol.375 , pp. 316
    • Nuez, B.1    Michalovich, D.2    Bygrave, A.3    Ploemacher, R.4    Grosveld, F.5
  • 16
    • 0028990264 scopus 로고
    • Lethal β-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF
    • Perkins AC, Sharpe AH, Orkin SH: Lethal β-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF. Nature 375:318, 1995
    • (1995) Nature , vol.375 , pp. 318
    • Perkins, A.C.1    Sharpe, A.H.2    Orkin, S.H.3
  • 17
    • 0028247214 scopus 로고
    • Cloning and functional characterization of LCR-F1: A novel transcription factor that activates erythroid-specific, human globin gene expression
    • Caterina JJ, Donze D, Sun C-W, Ciavatta DJ, Townes TM: Cloning and functional characterization of LCR-F1: A novel transcription factor that activates erythroid-specific, human globin gene expression. Nucleic Acids Res 22:2383, 1994
    • (1994) Nucleic Acids Res , vol.22 , pp. 2383
    • Caterina, J.J.1    Donze, D.2    Sun, C.-W.3    Ciavatta, D.J.4    Townes, T.M.5
  • 18
    • 0025325983 scopus 로고
    • The "megaprimer" method of site-directed mutagenesis
    • Sarkar G, Sommer SS: The "megaprimer" method of site-directed mutagenesis. Biotechniques 8:404, 1990
    • (1990) Biotechniques , vol.8 , pp. 404
    • Sarkar, G.1    Sommer, S.S.2
  • 19
    • 0025837559 scopus 로고
    • "Megaprimer" method of PCR: Increased template concentration improves yield
    • Barik S, Galinski M: "Megaprimer" method of PCR: Increased template concentration improves yield. Biotechniques 10:489, 1991
    • (1991) Biotechniques , vol.10 , pp. 489
    • Barik, S.1    Galinski, M.2
  • 20
    • 0027478063 scopus 로고
    • Modification of the megaprimer method of PCR mutagenesis: Improved amplification of the final product
    • Aiyar A, Leis J: Modification of the megaprimer method of PCR mutagenesis: Improved amplification of the final product. Biotechniques 14:366, 1993
    • (1993) Biotechniques , vol.14 , pp. 366
    • Aiyar, A.1    Leis, J.2
  • 21
    • 0021924399 scopus 로고
    • Specific DNA binding of GAL4, a positive regulatory protein of yeast
    • Giniger E, Varnum S, Ptashne M: Specific DNA binding of GAL4, a positive regulatory protein of yeast. Cell 40:767, 1985
    • (1985) Cell , vol.40 , pp. 767
    • Giniger, E.1    Varnum, S.2    Ptashne, M.3
  • 22
    • 0028357241 scopus 로고
    • Multiple elements in human β-globin locus control region 5′ HS 2 are involved in enhancer activity and position-independent, transgene expression
    • Caterina JJ, Ciavatta DJ, Donze D, Behringer RR, Townes TM: Multiple elements in human β-globin locus control region 5′ HS 2 are involved in enhancer activity and position-independent, transgene expression. Nucleic Acids Res 22:1006, 1994
    • (1994) Nucleic Acids Res , vol.22 , pp. 1006
    • Caterina, J.J.1    Ciavatta, D.J.2    Donze, D.3    Behringer, R.R.4    Townes, T.M.5
  • 23
    • 0025101148 scopus 로고
    • Definition of the minimal requirements within the human β-globin gene and the dominant control region for high level expression
    • Collis P, Antoniou M, Grosveld F: Definition of the minimal requirements within the human β-globin gene and the dominant control region for high level expression. EMBO J 9:233, 1990
    • (1990) EMBO J , vol.9 , pp. 233
    • Collis, P.1    Antoniou, M.2    Grosveld, F.3
  • 24
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156, 1987
    • (1987) Anal Biochem , vol.162 , pp. 156
    • Chomczynski, P.1    Sacchi, N.2
  • 25
    • 0029142492 scopus 로고
    • Biallelic expression of imprinted genes in the mouse germline: Implications for erasure, establishment, and mechanisms of genomic imprinting
    • Szabo PE, Mann JR: Biallelic expression of imprinted genes in the mouse germline: Implications for erasure, establishment, and mechanisms of genomic imprinting. Genes Dev 9:1857, 1995
    • (1995) Genes Dev , vol.9 , pp. 1857
    • Szabo, P.E.1    Mann, J.R.2
  • 26
    • 0026674981 scopus 로고
    • Erythroid-specific activity of the glycophorin B promoter requires GATA-1 mediated displacement of a repressor
    • Rahuel C, Vinit MA, Lemarchandel V, Cartron JP, Romeo PH: Erythroid-specific activity of the glycophorin B promoter requires GATA-1 mediated displacement of a repressor. EMBO J 11:4095, 1992
    • (1992) EMBO J , vol.11 , pp. 4095
    • Rahuel, C.1    Vinit, M.A.2    Lemarchandel, V.3    Cartron, J.P.4    Romeo, P.H.5
  • 27
    • 0028074197 scopus 로고
    • Displacement of an E-box-binding repressor by basic helix-loop-helix proteins: Implications for B-cell specificity of the immunoglobulin heavy-chain enhancer
    • Genetta T, Ruezinsky D, Kadesch T: Displacement of an E-box-binding repressor by basic helix-loop-helix proteins: Implications for B-cell specificity of the immunoglobulin heavy-chain enhancer. Mol Cell Biol 14:6153, 1994
    • (1994) Mol Cell Biol , vol.14 , pp. 6153
    • Genetta, T.1    Ruezinsky, D.2    Kadesch, T.3
  • 28
    • 0022423672 scopus 로고
    • DNA sequences regulating human β-globin gene expression
    • Kosche KA, Dobkin C, Bank A: DNA sequences regulating human β-globin gene expression. Nucleic Acids Res 13:7781, 1985
    • (1985) Nucleic Acids Res , vol.13 , pp. 7781
    • Kosche, K.A.1    Dobkin, C.2    Bank, A.3
  • 30
    • 0020624843 scopus 로고
    • Human β- and δ-globin messenger RNAs turn over at different rates
    • Ross J, Pizarro A: Human β- and δ-globin messenger RNAs turn over at different rates. J Mol Biol 167:607, 1983
    • (1983) J Mol Biol , vol.167 , pp. 607
    • Ross, J.1    Pizarro, A.2
  • 32
    • 0021818675 scopus 로고
    • Filamentous fusion phage: Novel expression vectors that display cloned antigens on the virion surface
    • Smith G: Filamentous fusion phage: Novel expression vectors that display cloned antigens on the virion surface. Science 228:1315, 1985
    • (1985) Science , vol.228 , pp. 1315
    • Smith, G.1
  • 33
    • 0027994717 scopus 로고
    • Toward a code for the interactions of zinc fingers with DNA: Selection of randomized fingers displayed on phage
    • Choo Y, Klug A: Toward a code for the interactions of zinc fingers with DNA: Selection of randomized fingers displayed on phage. Proc Natl Acad Sci USA 91:11163, 1994
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11163
    • Choo, Y.1    Klug, A.2
  • 34
    • 0028227930 scopus 로고
    • In vitro selection of zinc fingers with altered DNA binding specificity
    • Jamieson AC, Kim S-H, Wells JA: In vitro selection of zinc fingers with altered DNA binding specificity. Biochemistry 33:5689, 1994
    • (1994) Biochemistry , vol.33 , pp. 5689
    • Jamieson, A.C.1    Kim, S.-H.2    Wells, J.A.3
  • 35
    • 0028328872 scopus 로고
    • Zinc finger phage: Affinity selection of fingers with new DNA binding specificities
    • Rebar EJ, Pabo CO: Zinc finger phage: Affinity selection of fingers with new DNA binding specificities. Science 263:671, 1994
    • (1994) Science , vol.263 , pp. 671
    • Rebar, E.J.1    Pabo, C.O.2
  • 36
    • 0028888530 scopus 로고
    • Building zinc fingers by selection: Toward a therapeutic application
    • Wu H, Yang W-P, Barbas CF: Building zinc fingers by selection: Toward a therapeutic application. Proc Natl Acad Sci USA 92:344, 1995
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 344
    • Wu, H.1    Yang, W.-P.2    Barbas, C.F.3
  • 37
    • 0028670569 scopus 로고
    • In vivo repression by a site-specific DNA-binding protein designed against an oncogenic sequence
    • Choo Y, Sanchez-Garcia I, Klug A: In vivo repression by a site-specific DNA-binding protein designed against an oncogenic sequence. Nature 372:642, 1994
    • (1994) Nature , vol.372 , pp. 642
    • Choo, Y.1    Sanchez-Garcia, I.2    Klug, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.