Genotoxic potential of lineage-specific lentivirus vectors carrying the β-Globin locus control region

Molecular Therapy

Volumn 17, Issue 11, 2009, Pages 1929-1937

  Arumugam, Paritha I ^a   Higashimoto, Tomoyasu ^a   Urbinati, Fabrizia ^a   Modlich, Ute ^b   Nestheide, Shawna ^a   Xia, Ping ^a   Fox, Catherine ^a   Corsinotti, Andrea ^a   Baum, Christopher ^a,b   Malik, Punam ^a  

^a CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN; LENTIVIRUS VECTOR; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CELL ASSAY; CELL IMMORTALIZATION; CONTROLLED STUDY; ERYTHROID CELL; GENE EXPRESSION; GENE LOCUS; GENOTOXICITY; HEMATOPOIETIC STEM CELL; IN VITRO STUDY; INSULATOR ELEMENT; MOUSE; MUTANT; NONHUMAN; REGULATOR GENE; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; BETA-GLOBINS; BONE MARROW CELLS; CELLS, CULTURED; GENETIC VECTORS; INSULATOR ELEMENTS; LENTIVIRUS; LOCUS CONTROL REGION; MICE; MICE, INBRED C57BL; MUTAGENESIS, INSERTIONAL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSDUCTION, GENETIC;

ANIMALIA; LENTIVIRUS; MUS;

EID: 70449127224     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2009.183     Document Type: Article

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