Nanoparticles deliver triplex-forming PNAs for site-specific genomic recombination in CD34+ human hematopoietic progenitors

Molecular Therapy

Volumn 19, Issue 1, 2011, Pages 172-180

  McNeer, Nicole A ^a   Chin, Joanna Y ^b   Schleifman, Erica B ^b   Fields, Rachel J ^a   Glazer, Peter M ^b   Saltzman, W Mark ^a  

^a Yale University   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBULIN; CD34 ANTIGEN; GENOMIC DNA; NANOPARTICLE; OLIGONUCLEOTIDE; PLASMID DNA; POLYGLACTIN; TRIPLEX FORMING PEPTIDE NUCLEIC ACID; UNCLASSIFIED DRUG;

ARTICLE; BIODEGRADABILITY; CELL DIFFERENTIATION; CELL LOSS; CELL VIABILITY; CONTROLLED STUDY; DNA MODIFICATION; DNA RECOMBINATION; DRUG DELIVERY SYSTEM; GENE LOCUS; GENE MUTATION; GENE TARGETING; GENETIC TRANSFECTION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; HUMAN GENOME;

EID: 78650919363     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2010.200     Document Type: Article

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