-
1
-
-
34548694962
-
Innate recognition of viruses
-
Pichlmair A, Reis e Sousa C. Innate recognition of viruses. Immunity 2007;27:370-383.
-
(2007)
Immunity
, vol.27
, pp. 370-383
-
-
Pichlmair, A.1
Reis e Sousa, C.2
-
2
-
-
35748937030
-
Recognition of viruses by innate immunity
-
Takeuchi O, Akira S. Recognition of viruses by innate immunity. Immunol Rev 2007;220:214-224.
-
(2007)
Immunol Rev
, vol.220
, pp. 214-224
-
-
Takeuchi, O.1
Akira, S.2
-
3
-
-
33750984771
-
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates
-
Pichlmair A, et al. RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates. Science 2006;314:997-1001.
-
(2006)
Science
, vol.314
, pp. 997-1001
-
-
Pichlmair, A.1
-
4
-
-
33750976374
-
5'-Triphosphate RNA is the ligand for RIG-I
-
Hornung V, et al. 5'-Triphosphate RNA is the ligand for RIG-I. Science 2006;314:994-997.
-
(2006)
Science
, vol.314
, pp. 994-997
-
-
Hornung, V.1
-
5
-
-
33646342149
-
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
-
Kato H, et al. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 2006;441:101-105.
-
(2006)
Nature
, vol.441
, pp. 101-105
-
-
Kato, H.1
-
6
-
-
33744791510
-
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus
-
Gitlin L, et al. Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus. Proc Natl Acad Sci USA 2006;103:8459-8464.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 8459-8464
-
-
Gitlin, L.1
-
7
-
-
78751637122
-
Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5
-
Züst R, et al. Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5. Nat Immunol 2011;12:137-143.
-
(2011)
Nat Immunol
, vol.12
, pp. 137-143
-
-
Züst, R.1
-
8
-
-
27144440523
-
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
-
Kawai T, et al. IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat Immunol 2005;6:981-988.
-
(2005)
Nat Immunol
, vol.6
, pp. 981-988
-
-
Kawai, T.1
-
9
-
-
24144461689
-
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3
-
Seth RB, Sun L, Ea CK, Chen ZJ. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 2005;122:669-682.
-
(2005)
Cell
, vol.122
, pp. 669-682
-
-
Seth, R.B.1
Sun, L.2
Ea, C.K.3
Chen, Z.J.4
-
10
-
-
27144440476
-
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
-
Meylan E, et al. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 2005;437:1167-1172.
-
(2005)
Nature
, vol.437
, pp. 1167-1172
-
-
Meylan, E.1
-
11
-
-
34447643958
-
Toll-like receptor 4 is a sensor for autophagy associated with innate immunity
-
Xu Y, Jagannath C, Liu X-D, Sharafkhaneh A, Kolodziejska KE, Eissa NT. Toll-like receptor 4 is a sensor for autophagy associated with innate immunity. Immunity 2007;27:135-144.
-
(2007)
Immunity
, vol.27
, pp. 135-144
-
-
Xu, Y.1
Jagannath, C.2
Liu, X.-D.3
Sharafkhaneh, A.4
Kolodziejska, K.E.5
Eissa, N.T.6
-
12
-
-
24944538819
-
VISA is an adapter protein required for virus-triggered IFN-beta signaling
-
Xu LG, Wang YY, Han KJ, Li LY, Zhai Z, Shu HB. VISA is an adapter protein required for virus-triggered IFN-beta signaling. Mol Cell 2005;19:727-740.
-
(2005)
Mol Cell
, vol.19
, pp. 727-740
-
-
Xu, L.G.1
Wang, Y.Y.2
Han, K.J.3
Li, L.Y.4
Zhai, Z.5
Shu, H.B.6
-
13
-
-
77951044335
-
DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-β-inducing potential
-
Oshiumi H, Sakai K, Matsumoto M, Seya T. DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-β-inducing potential. Eur J Immunol 2010;40:940-948.
-
(2010)
Eur J Immunol
, vol.40
, pp. 940-948
-
-
Oshiumi, H.1
Sakai, K.2
Matsumoto, M.3
Seya, T.4
-
14
-
-
49149113373
-
Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKε-mediated IRF activation
-
Schröder M, Baran M, Bowie AG. Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKε-mediated IRF activation. EMBO J 2008;27:2147-2157.
-
(2008)
EMBO J
, vol.27
, pp. 2147-2157
-
-
Schröder, M.1
Baran, M.2
Bowie, A.G.3
-
15
-
-
43049174990
-
TRADD protein is an essential component of the RIG-like helicase antiviral pathway
-
Michallet M, et al. TRADD protein is an essential component of the RIG-like helicase antiviral pathway. Immunity 2008;28:651-661.
-
(2008)
Immunity
, vol.28
, pp. 651-661
-
-
Michallet, M.1
-
16
-
-
53349178089
-
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
-
Ishikawa H, Barber GN. STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. Nature 2008;455:674-678.
-
(2008)
Nature
, vol.455
, pp. 674-678
-
-
Ishikawa, H.1
Barber, G.N.2
-
17
-
-
53349168904
-
The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation
-
Zhong B, et al. The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation. Immunity 2008;29:538-550.
-
(2008)
Immunity
, vol.29
, pp. 538-550
-
-
Zhong, B.1
-
18
-
-
49449115516
-
MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals
-
Jin L, Waterman PM, Jonscher KR, Short CM, Reisdorph NA, Cambier JC. MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals. Mol Cell Biol 2008;28:5014-5026.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5014-5026
-
-
Jin, L.1
Waterman, P.M.2
Jonscher, K.R.3
Short, C.M.4
Reisdorph, N.A.5
Cambier, J.C.6
-
19
-
-
66649109939
-
ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization
-
Sun W, et al. ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization. Proc Natl Acad Sci USA 2009;106:8653-8658.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 8653-8658
-
-
Sun, W.1
-
20
-
-
66049088727
-
ISG56 is a negative-feedback regulator of virus-triggered signaling and cellular antiviral response
-
Li Y, et al. ISG56 is a negative-feedback regulator of virus-triggered signaling and cellular antiviral response. Proc Natl Acad Sci USA 2009;106:7945-7950.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 7945-7950
-
-
Li, Y.1
-
21
-
-
30444450839
-
Recognition of cytosolic DNA activates an IRF3-dependent innate immune response
-
Stetson DB, Medzhitov R. Recognition of cytosolic DNA activates an IRF3-dependent innate immune response. Immunity 2006;24:93-103.
-
(2006)
Immunity
, vol.24
, pp. 93-103
-
-
Stetson, D.B.1
Medzhitov, R.2
-
22
-
-
29244471275
-
A toll-like receptor-independent antiviral response induced by double-stranded B-form DNA
-
Ishii KJ, et al. A toll-like receptor-independent antiviral response induced by double-stranded B-form DNA. Nat Immunol 2006;7:40-48.
-
(2006)
Nat Immunol
, vol.7
, pp. 40-48
-
-
Ishii, K.J.1
-
23
-
-
34547143110
-
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
-
Takaoka A, et al. DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature 2007;448:501-505.
-
(2007)
Nature
, vol.448
, pp. 501-505
-
-
Takaoka, A.1
-
24
-
-
38949093002
-
TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines
-
Ishii KJ, et al. TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines. Nature 2008;451:725-729.
-
(2008)
Nature
, vol.451
, pp. 725-729
-
-
Ishii, K.J.1
-
25
-
-
68049092912
-
RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway
-
Chiu YH, MacMillan JB, Chen ZJ. RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway. Cell 2009;138:576-591.
-
(2009)
Cell
, vol.138
, pp. 576-591
-
-
Chiu, Y.H.1
MacMillan, J.B.2
Chen, Z.J.3
-
26
-
-
70349459734
-
RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate
-
Ablasser A, Bauernfeind F, Hartmann G, Latz E, Fitzgerald KA, Hornung V. RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate. Nat Immunol 2009;10:1065-1072.
-
(2009)
Nat Immunol
, vol.10
, pp. 1065-1072
-
-
Ablasser, A.1
Bauernfeind, F.2
Hartmann, G.3
Latz, E.4
Fitzgerald, K.A.5
Hornung, V.6
-
27
-
-
77956275377
-
Inhibition of the RNA polymerase III-mediated dsDNA-sensing pathway of innate immunity by vaccinia virus protein E3
-
Valentine R, Smith GL. Inhibition of the RNA polymerase III-mediated dsDNA-sensing pathway of innate immunity by vaccinia virus protein E3. J Gen Virol 2010;91:2221-2229.
-
(2010)
J Gen Virol
, vol.91
, pp. 2221-2229
-
-
Valentine, R.1
Smith, G.L.2
-
28
-
-
77958140656
-
IFI16 is an innate immune sensor for intracellular DNA
-
Unterholzner L, et al. IFI16 is an innate immune sensor for intracellular DNA. Nat Immunol 2010;11:997-1004.
-
(2010)
Nat Immunol
, vol.11
, pp. 997-1004
-
-
Unterholzner, L.1
-
29
-
-
73949083594
-
Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response
-
Saitoh T, et al. Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response. Proc Natl Acad Sci USA 2009;106:20842-20846.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 20842-20846
-
-
Saitoh, T.1
-
31
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-β
-
Martinon F, Burns K, Tschopp J. The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-β. Mol Cell 2002;10:417-426.
-
(2002)
Mol Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
32
-
-
0036398446
-
The IL-1 family and inflammatory diseases
-
Dinarello CA. The IL-1 family and inflammatory diseases. Clin Exp Rheumatol 2002;20(5 Suppl. 27):S1-S13.
-
(2002)
Clin Exp Rheumatol
, vol.20
, Issue.5 SUPPL. 27
-
-
Dinarello, C.A.1
-
33
-
-
40449140937
-
The NLR gene family: a standard nomenclature
-
Ting JP, et al. The NLR gene family: a standard nomenclature. Immunity 2008;28:285-287.
-
(2008)
Immunity
, vol.28
, pp. 285-287
-
-
Ting, J.P.1
-
34
-
-
78649526394
-
Sterile inflammation: sensing and reacting to damage
-
Chen GY, Nunez G. Sterile inflammation: sensing and reacting to damage. Nat Rev Immunol 2010;10:826-837.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 826-837
-
-
Chen, G.Y.1
Nunez, G.2
-
35
-
-
33846014297
-
Critical role for cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA
-
Kanneganti T, et al. Critical role for cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA. J Biol Chem 2006;281:36560-36568.
-
(2006)
J Biol Chem
, vol.281
, pp. 36560-36568
-
-
Kanneganti, T.1
-
36
-
-
40449097257
-
The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
-
Muruve DA, et al. The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response. Nature 2008;452:103-107.
-
(2008)
Nature
, vol.452
, pp. 103-107
-
-
Muruve, D.A.1
-
37
-
-
77951295418
-
Influenza virus activates inflammasomes via its intracellular M2 ion channel
-
Ichinohe T, Pang IK, Iwasaki A. Influenza virus activates inflammasomes via its intracellular M2 ion channel. Nat Immunol 2010;11:404-410.
-
(2010)
Nat Immunol
, vol.11
, pp. 404-410
-
-
Ichinohe, T.1
Pang, I.K.2
Iwasaki, A.3
-
38
-
-
60749136484
-
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
-
Bürckstümmer T, et al. An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. Nat Immunol 2009;10:266-272.
-
(2009)
Nat Immunol
, vol.10
, pp. 266-272
-
-
Bürckstümmer, T.1
-
39
-
-
63649133278
-
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
-
Hornung V, et al. AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature 2009;458:514-518.
-
(2009)
Nature
, vol.458
, pp. 514-518
-
-
Hornung, V.1
-
40
-
-
63649145255
-
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
-
Fernandes-Alnemri T, Yu J, Datta P, Wu J, Alnemri ES. AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature 2009;458:509-513.
-
(2009)
Nature
, vol.458
, pp. 509-513
-
-
Fernandes-Alnemri, T.1
Yu, J.2
Datta, P.3
Wu, J.4
Alnemri, E.S.5
-
41
-
-
60749104535
-
HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA
-
Roberts TL, et al. HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA. Science 2009;323:1057-1060.
-
(2009)
Science
, vol.323
, pp. 1057-1060
-
-
Roberts, T.L.1
-
42
-
-
70349459620
-
Activation of innate immune antiviral responses by Nod2
-
Sabbah A, et al. Activation of innate immune antiviral responses by Nod2. Nat Immunol 2009;10:1073-1080.
-
(2009)
Nat Immunol
, vol.10
, pp. 1073-1080
-
-
Sabbah, A.1
-
43
-
-
70450223512
-
Nucleotide oligomerization domain-2 interacts with 2'-5'-oligoadenylate synthetase type 2 and enhances RNase-L function in THP-1 cells
-
Dugan JW, et al. Nucleotide oligomerization domain-2 interacts with 2'-5'-oligoadenylate synthetase type 2 and enhances RNase-L function in THP-1 cells. Mol Immunol 2009;47:560-566.
-
(2009)
Mol Immunol
, vol.47
, pp. 560-566
-
-
Dugan, J.W.1
-
44
-
-
34547960175
-
Small self-RNA generated by RNase L amplifies antiviral innate immunity
-
Malathi K, Dong B, Gale M Jr, Silverman RH. Small self-RNA generated by RNase L amplifies antiviral innate immunity. Nature 2007;448:816-819.
-
(2007)
Nature
, vol.448
, pp. 816-819
-
-
Malathi, K.1
Dong, B.2
Gale Jr., M.3
Silverman, R.H.4
-
45
-
-
79952125382
-
Activation of IFN-β expression by a viral mRNA through RNase L and MDA5
-
Luthra P, Sun D, Silverman RH, He B. Activation of IFN-β expression by a viral mRNA through RNase L and MDA5. Proc Natl Acad Sci USA 2011;108:2118-2123.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 2118-2123
-
-
Luthra, P.1
Sun, D.2
Silverman, R.H.3
He, B.4
-
46
-
-
38749097018
-
NLRX1 is a regulator of mitochondrial antiviral immunity
-
Moore CB, et al. NLRX1 is a regulator of mitochondrial antiviral immunity. Nature 2008;451:573-577.
-
(2008)
Nature
, vol.451
, pp. 573-577
-
-
Moore, C.B.1
-
47
-
-
40249111682
-
NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-κB and JNK pathways by inducing reactive oxygen species production
-
Tattoli I, et al. NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-κB and JNK pathways by inducing reactive oxygen species production. EMBO Rep 2008;9:293-300.
-
(2008)
EMBO Rep
, vol.9
, pp. 293-300
-
-
Tattoli, I.1
-
48
-
-
74049126045
-
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1Β production
-
Poeck H, et al. Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1Β production. Nat Immunol 2010;11:63-69.
-
(2010)
Nat Immunol
, vol.11
, pp. 63-69
-
-
Poeck, H.1
-
49
-
-
70350464358
-
CARD9 facilitates microbe-elicited production of reactive oxygen species by regulating the LyGDI-Rac1 complex
-
Wu W, Hsu YM, Bi L, Songyang Z, Lin X. CARD9 facilitates microbe-elicited production of reactive oxygen species by regulating the LyGDI-Rac1 complex. Nat Immunol 2009;10:1208-1214.
-
(2009)
Nat Immunol
, vol.10
, pp. 1208-1214
-
-
Wu, W.1
Hsu, Y.M.2
Bi, L.3
Songyang, Z.4
Lin, X.5
-
50
-
-
70350380878
-
DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses
-
Lipinski S, et al. DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses. J Cell Sci 2009;122:3522-3530.
-
(2009)
J Cell Sci
, vol.122
, pp. 3522-3530
-
-
Lipinski, S.1
-
51
-
-
33846469538
-
The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens
-
Hsu Y-S, et al. The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens. Nat Immunol 2007;8:198-205.
-
(2007)
Nat Immunol
, vol.8
, pp. 198-205
-
-
Hsu, Y.-S.1
-
52
-
-
13944278132
-
Mitochondria, oxidants, and aging
-
Balaban RS, Nemoto S, Finkel T. Mitochondria, oxidants, and aging. Cell 2005;120:483-495.
-
(2005)
Cell
, vol.120
, pp. 483-495
-
-
Balaban, R.S.1
Nemoto, S.2
Finkel, T.3
-
53
-
-
45049085873
-
Redox-based regulation of signal transduction: Principles, pitfalls, and promises
-
Janssen-Heininger YMW, et al. Redox-based regulation of signal transduction: Principles, pitfalls, and promises. Free Radic Biol Med 2008;45:1-17.
-
(2008)
Free Radic Biol Med
, vol.45
, pp. 1-17
-
-
Janssen-Heininger, Y.M.W.1
-
54
-
-
0034626735
-
Oxidants, oxidative stress and the biology of ageing
-
Finkel T, Holbrook NJ. Oxidants, oxidative stress and the biology of ageing. Nature 2000;408:239-247.
-
(2000)
Nature
, vol.408
, pp. 239-247
-
-
Finkel, T.1
Holbrook, N.J.2
-
55
-
-
77951737783
-
Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations
-
Chen H, et al. Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations. Cell 2010;141:280-289.
-
(2010)
Cell
, vol.141
, pp. 280-289
-
-
Chen, H.1
-
56
-
-
1542283812
-
In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
-
Mizushima N, Yamamoto A, Matsui M, Yoshimori T, Ohsumi Y. In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell 2004;15:1101-1111.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 1101-1111
-
-
Mizushima, N.1
Yamamoto, A.2
Matsui, M.3
Yoshimori, T.4
Ohsumi, Y.5
-
57
-
-
0035286734
-
Molecular dissection of autophagy: two ubiquitin-like systems
-
Ohsumi Y. Molecular dissection of autophagy: two ubiquitin-like systems. Nat Rev Mol Cell Biol 2001;2:211-216.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 211-216
-
-
Ohsumi, Y.1
-
58
-
-
65249108735
-
Autophagy genes in immunity
-
Virgin HW, Levine B. Autophagy genes in immunity. Nat Immunol 2009;10:461-470.
-
(2009)
Nat Immunol
, vol.10
, pp. 461-470
-
-
Virgin, H.W.1
Levine, B.2
-
59
-
-
75649089762
-
Autophagy and innate recognition systems
-
Tal MC, Iwasaki A. Autophagy and innate recognition systems. Curr Top Microbiol Immunol 2009;335:107-121.
-
(2009)
Curr Top Microbiol Immunol
, vol.335
, pp. 107-121
-
-
Tal, M.C.1
Iwasaki, A.2
-
60
-
-
33644606491
-
Tracker dyes to probe mitochondrial autophagy (mitophagy) in rat hepatocytes
-
Rodriguez-Enriquez S, Kim I, Currin RT, Lemasters JJ. Tracker dyes to probe mitochondrial autophagy (mitophagy) in rat hepatocytes. Autophagy 2006;2:39-46.
-
(2006)
Autophagy
, vol.2
, pp. 39-46
-
-
Rodriguez-Enriquez, S.1
Kim, I.2
Currin, R.T.3
Lemasters, J.J.4
-
61
-
-
38549110110
-
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
-
Twig G, et al. Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. EMBO J 2008;27:433-446.
-
(2008)
EMBO J
, vol.27
, pp. 433-446
-
-
Twig, G.1
-
62
-
-
79952184583
-
Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)
-
Bulua AC, et al. Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS). J Exp Med 2011;208:519-533.
-
(2011)
J Exp Med
, vol.208
, pp. 519-533
-
-
Bulua, A.C.1
-
63
-
-
62449110463
-
Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling
-
Tal MC, Sasai M, Lee HK, Yordy B, Shadel GS, Iwasaki A. Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling. Proc Natl Acad Sci USA 2009;106:2774-2775.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 2774-2775
-
-
Tal, M.C.1
Sasai, M.2
Lee, H.K.3
Yordy, B.4
Shadel, G.S.5
Iwasaki, A.6
-
64
-
-
33750523632
-
NF-κB activation by reactive oxygen species: Fifteen years later
-
Gloire G, Legrand-Poels S, Piette J. NF-κB activation by reactive oxygen species: Fifteen years later. Biochem Pharmacol 2006;72:1493-1505.
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 1493-1505
-
-
Gloire, G.1
Legrand-Poels, S.2
Piette, J.3
-
65
-
-
77954680592
-
Requirement of NOX2 and reactive oxygen species for efficient RIG-I-mediated antiviral response through regulation of MAVS expression
-
Soucy-Faulkner A, et al. Requirement of NOX2 and reactive oxygen species for efficient RIG-I-mediated antiviral response through regulation of MAVS expression. PLoS Pathog 2010;6:e1000930.
-
(2010)
PLoS Pathog
, vol.6
-
-
Soucy-Faulkner, A.1
-
66
-
-
33744913266
-
Dissociation of a MAVS/IPS-1/VISA/cardif-IKKε molecular complex from the mitochondrial outer membrane by hepatitis C virus NS3-4A proteolytic cleavage
-
Lin R, et al. Dissociation of a MAVS/IPS-1/VISA/cardif-IKKε molecular complex from the mitochondrial outer membrane by hepatitis C virus NS3-4A proteolytic cleavage. J Virol 2006;80:6072-6083.
-
(2006)
J Virol
, vol.80
, pp. 6072-6083
-
-
Lin, R.1
-
67
-
-
64049090624
-
MAVS self-association mediates antiviral innate immune signaling
-
Tang ED, Wang C. MAVS self-association mediates antiviral innate immune signaling. J Virol 2009;83:3420-3428.
-
(2009)
J Virol
, vol.83
, pp. 3420-3428
-
-
Tang, E.D.1
Wang, C.2
-
68
-
-
77952503750
-
Peroxisomes are signaling platforms for antiviral innate immunity
-
Dixit E, et al. Peroxisomes are signaling platforms for antiviral innate immunity. Cell 2010;141:668-681.
-
(2010)
Cell
, vol.141
, pp. 668-681
-
-
Dixit, E.1
-
69
-
-
66949149847
-
Actin and RIG-I/MAVS signaling components translocate to mitochondria upon influenza A virus infection of human primary macrophages
-
Ohman T, Rintahaka J, Kalkkinen N, Matikainen S, Nyman TA. Actin and RIG-I/MAVS signaling components translocate to mitochondria upon influenza A virus infection of human primary macrophages. J Immunol 2009;182:5682-5692.
-
(2009)
J Immunol
, vol.182
, pp. 5682-5692
-
-
Ohman, T.1
Rintahaka, J.2
Kalkkinen, N.3
Matikainen, S.4
Nyman, T.A.5
-
70
-
-
77956304154
-
Tom70 mediates activation of interferon regulatory factor 3 on mitochondria
-
Liu XY, Wei B, Shi HX, Shan YF, Wang C. Tom70 mediates activation of interferon regulatory factor 3 on mitochondria. Cell Res 2010;20:994-1011.
-
(2010)
Cell Res
, vol.20
, pp. 994-1011
-
-
Liu, X.Y.1
Wei, B.2
Shi, H.X.3
Shan, Y.F.4
Wang, C.5
-
71
-
-
34247265509
-
A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses
-
Mayor A, Martinon F, De Smedt T, Pétrilli V, Tschopp J. A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses. Nat Immunol 2007;8:497-503.
-
(2007)
Nat Immunol
, vol.8
, pp. 497-503
-
-
Mayor, A.1
Martinon, F.2
De Smedt, T.3
Pétrilli, V.4
Tschopp, J.5
-
72
-
-
34147192982
-
Cell-free assays for mitochondria-cytoskeleton interactions
-
Pon LA, Schon EA eds. New York: Academic Press
-
Boldogh IR, Pon LA, Sheetz MP, De Vos KJ. Cell-free assays for mitochondria-cytoskeleton interactions. In: Pon LA, Schon EA eds. Methods in Cell Biology. New York: Academic Press, 2007:683-706.
-
(2007)
Methods in Cell Biology
, pp. 683-706
-
-
Boldogh, I.R.1
Pon, L.A.2
Sheetz, M.P.3
De Vos, K.J.4
-
73
-
-
21744445111
-
The actin cytoskeleton: a key regulator of apoptosis and ageing?
-
Gourlay CW, Ayscough KR. The actin cytoskeleton: a key regulator of apoptosis and ageing? Nat Rev Mol Cell Biol 2005;6:583-589.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 583-589
-
-
Gourlay, C.W.1
Ayscough, K.R.2
-
74
-
-
77955276502
-
Organellar vs cellular control of mitochondrial dynamics
-
Hyde BB, Twig G, Shirihai OS. Organellar vs cellular control of mitochondrial dynamics. Semin Cell Dev Biol 2010;21:575-581.
-
(2010)
Semin Cell Dev Biol
, vol.21
, pp. 575-581
-
-
Hyde, B.B.1
Twig, G.2
Shirihai, O.S.3
-
75
-
-
75949098312
-
Mitochondrial dynamics regulate the RIG-I-like receptor antiviral pathway
-
Castanier C, Garcin D, Vazquez A, Arnoult D. Mitochondrial dynamics regulate the RIG-I-like receptor antiviral pathway. EMBO Rep 2010;11:133-138.
-
(2010)
EMBO Rep
, vol.11
, pp. 133-138
-
-
Castanier, C.1
Garcin, D.2
Vazquez, A.3
Arnoult, D.4
-
76
-
-
27144557499
-
A role for Fis1 in both mitochondrial and peroxisomal fission in mammalian cells
-
Koch A, Yoon Y, Bonekamp NA, McNiven MA, Schrader M. A role for Fis1 in both mitochondrial and peroxisomal fission in mammalian cells. Mol Biol Cell 2005;16:5077-5086.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 5077-5086
-
-
Koch, A.1
Yoon, Y.2
Bonekamp, N.A.3
McNiven, M.A.4
Schrader, M.5
-
77
-
-
0037424490
-
Dynamin-like protein 1 is involved in peroxisomal fission
-
Koch A, Thiemann M, Grabenbauer M, Yoon Y, McNiven MA, Schrader M. Dynamin-like protein 1 is involved in peroxisomal fission. J Biol Chem 2003;278:8597-8605.
-
(2003)
J Biol Chem
, vol.278
, pp. 8597-8605
-
-
Koch, A.1
Thiemann, M.2
Grabenbauer, M.3
Yoon, Y.4
McNiven, M.A.5
Schrader, M.6
-
78
-
-
70350468688
-
Mitofusin 2 inhibits mitochondrial antiviral signaling
-
Yasukawa K, et al. Mitofusin 2 inhibits mitochondrial antiviral signaling. Sci Signal 2009;2:ra47.
-
(2009)
Sci Signal
, vol.2
-
-
Yasukawa, K.1
-
79
-
-
57349100367
-
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
-
De Brito OM, Scorrano L. Mitofusin 2 tethers endoplasmic reticulum to mitochondria. Nature 2008;456:605-610.
-
(2008)
Nature
, vol.456
, pp. 605-610
-
-
De Brito, O.M.1
Scorrano, L.2
-
80
-
-
34548037901
-
Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium
-
Høyer-Hansen M, Jäättelä M. Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium. Cell Death Differ 2007;14:1576-1582.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1576-1582
-
-
Høyer-Hansen, M.1
Jäättelä, M.2
-
81
-
-
77957666242
-
Virus-infection or 5'ppp-RNA activates antiviral signal through redistribution of IPS-1 mediated by MFN1
-
Onoguchi K, et al. Virus-infection or 5'ppp-RNA activates antiviral signal through redistribution of IPS-1 mediated by MFN1. PLoS Pathog 2010;6:e1001012.
-
(2010)
PLoS Pathog
, vol.6
-
-
Onoguchi, K.1
-
82
-
-
79551716551
-
Mitochondrial membrane potential is required for MAVS-mediated antiviral signaling
-
Koshiba T, Yasukawa K, Yanagi Y, Kawabata S. Mitochondrial membrane potential is required for MAVS-mediated antiviral signaling. Sci Signal 2011;4:ra7.
-
(2011)
Sci Signal
, vol.4
-
-
Koshiba, T.1
Yasukawa, K.2
Yanagi, Y.3
Kawabata, S.4
-
83
-
-
77951274305
-
Uncoupling protein UCP2: When mitochondrial activity meets immunity
-
Emre Y, Nübel T. Uncoupling protein UCP2: When mitochondrial activity meets immunity. FEBS Lett 2010;584:1437-1442.
-
(2010)
FEBS Lett
, vol.584
, pp. 1437-1442
-
-
Emre, Y.1
Nübel, T.2
-
84
-
-
77749304032
-
Signaling by ROS drives inflammasome activation
-
Martinon F. Signaling by ROS drives inflammasome activation. Eur J Immunol 2010;40:616-619.
-
(2010)
Eur J Immunol
, vol.40
, pp. 616-619
-
-
Martinon, F.1
-
85
-
-
77649179433
-
NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production?
-
Tschopp J, Schroder K. NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production? Nat Rev Immunol 2010;10:210-215.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 210-215
-
-
Tschopp, J.1
Schroder, K.2
-
86
-
-
77955867246
-
Human NLRP3 inflammasome activation is Nox1-4 independent
-
Van Bruggen R, et al. Human NLRP3 inflammasome activation is Nox1-4 independent. Blood 2010;115:5398-5400.
-
(2010)
Blood
, vol.115
, pp. 5398-5400
-
-
Van Bruggen, R.1
-
87
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
Nakahira K, et al. Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol 2011;12:222-230.
-
(2011)
Nat Immunol
, vol.12
, pp. 222-230
-
-
Nakahira, K.1
-
88
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
Zhou R, Yazdi AS, Menu P, Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature 2011;469:221-226.
-
(2011)
Nature
, vol.469
, pp. 221-226
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
-
89
-
-
56249090667
-
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production
-
Saitoh T, et al. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature 2008;456:264-268.
-
(2008)
Nature
, vol.456
, pp. 264-268
-
-
Saitoh, T.1
-
90
-
-
79953176280
-
Autophagy controls IL-1β secretion by targeting pro-IL-1β for degradation
-
Harris J, et al. Autophagy controls IL-1β secretion by targeting pro-IL-1β for degradation. J Biol Chem 2011;286:9587-9597.
-
(2011)
J Biol Chem
, vol.286
, pp. 9587-9597
-
-
Harris, J.1
-
91
-
-
77649260429
-
Reactive oxygen species-independent activation of the IL-1β inflammasome in cells from patients with chronic granulomatous disease
-
Van De Veerdonk FL, et al. Reactive oxygen species-independent activation of the IL-1β inflammasome in cells from patients with chronic granulomatous disease. Proc Natl Acad Sci USA 2010;107:3030-3033.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 3030-3033
-
-
Van De Veerdonk, F.L.1
-
92
-
-
47849120473
-
Superoxide dismutase 1 regulates caspase-1 and endotoxic shock
-
Meissner F, Molawi K, Zychlinsky A. Superoxide dismutase 1 regulates caspase-1 and endotoxic shock. Nat Immunol 2008;9:866-872.
-
(2008)
Nat Immunol
, vol.9
, pp. 866-872
-
-
Meissner, F.1
Molawi, K.2
Zychlinsky, A.3
-
93
-
-
78049281933
-
Drosophila porin/VDAC affects mitochondrial morphology
-
Park J, et al. Drosophila porin/VDAC affects mitochondrial morphology. PLoS ONE 2010;5:e13151.
-
(2010)
PLoS ONE
, vol.5
-
-
Park, J.1
-
94
-
-
77952886494
-
VDAC, a multi-functional mitochondrial protein regulating cell life and death
-
Shoshan-Barmatz V, De Pinto V, Zweckstetter M, Raviv Z, Keinan N, Arbel N. VDAC, a multi-functional mitochondrial protein regulating cell life and death. Mol Asp Med 2010;31:227-285.
-
(2010)
Mol Asp Med
, vol.31
, pp. 227-285
-
-
Shoshan-Barmatz, V.1
De Pinto, V.2
Zweckstetter, M.3
Raviv, Z.4
Keinan, N.5
Arbel, N.6
-
95
-
-
52449104836
-
VDAC regulation: role of cytosolic proteins and mitochondrial lipids
-
Rostovtseva TK, Bezrukov SM. VDAC regulation: role of cytosolic proteins and mitochondrial lipids. J Bioenerg Biomembr 2008;40:163-170.
-
(2008)
J Bioenerg Biomembr
, vol.40
, pp. 163-170
-
-
Rostovtseva, T.K.1
Bezrukov, S.M.2
-
96
-
-
34247895699
-
Mitochondrial apoptosis without VDAC
-
Galluzzi L, Kroemer G. Mitochondrial apoptosis without VDAC. Nature Cell Biol 2007;9:487-489.
-
(2007)
Nature Cell Biol
, vol.9
, pp. 487-489
-
-
Galluzzi, L.1
Kroemer, G.2
-
98
-
-
77953808124
-
Characterization of human VDAC isoforms: A peculiar function for VDAC3?
-
De Pinto V, et al. Characterization of human VDAC isoforms: A peculiar function for VDAC3? Biochimica et Biophysica Acta 2010;1797:1268-1275.
-
(2010)
Biochimica et Biophysica Acta
, vol.1797
, pp. 1268-1275
-
-
De Pinto, V.1
-
99
-
-
75649096002
-
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
-
Zhou R, Tardivel A, Thorens B, Choi I, Tschopp J. Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat Immunol 2010;11:136-140.
-
(2010)
Nat Immunol
, vol.11
, pp. 136-140
-
-
Zhou, R.1
Tardivel, A.2
Thorens, B.3
Choi, I.4
Tschopp, J.5
-
100
-
-
77950275298
-
Circulating mitochondrial DAMPs cause inflammatory responses to injury
-
Zhang Q, et al. Circulating mitochondrial DAMPs cause inflammatory responses to injury. Nature 2010;464:104-107.
-
(2010)
Nature
, vol.464
, pp. 104-107
-
-
Zhang, Q.1
-
101
-
-
51349135381
-
Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense
-
Yousefi S, et al. Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense. Nat Med 2008;14:949-953.
-
(2008)
Nat Med
, vol.14
, pp. 949-953
-
-
Yousefi, S.1
-
102
-
-
67649236138
-
Mitochondrial complementation preventing respiratory dysfunction caused by mutant mtDNA
-
Sato A, Nakada K, Hayashi J-I. Mitochondrial complementation preventing respiratory dysfunction caused by mutant mtDNA. Biofactors 2009;35:130-137.
-
(2009)
Biofactors
, vol.35
, pp. 130-137
-
-
Sato, A.1
Nakada, K.2
Hayashi, J.-I.3
-
103
-
-
78650829528
-
Gene transfer: anything goes in plant mitochondria
-
Archibald JM, Richards TA. Gene transfer: anything goes in plant mitochondria. BMC Biol 2010;8:147.
-
(2010)
BMC Biol
, vol.8
, pp. 147
-
-
Archibald, J.M.1
Richards, T.A.2
-
104
-
-
77953091249
-
Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity
-
Henis-Korenblit S, et al. Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity. Proc Natl Acad Sci USA 2010;107:9730-9735.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 9730-9735
-
-
Henis-Korenblit, S.1
-
105
-
-
77649135472
-
An essential role for XBP-1 in host protection against immune activation in C. elegans
-
Richardson CE, Kooistra T, Kim DH. An essential role for XBP-1 in host protection against immune activation in C. elegans. Nature 2010;463:1092-1095.
-
(2010)
Nature
, vol.463
, pp. 1092-1095
-
-
Richardson, C.E.1
Kooistra, T.2
Kim, D.H.3
-
106
-
-
47049098902
-
Endoplasmic reticulum stress and the unfolded protein response are linked to synergistic IFN-β induction via X-box binding protein 1
-
Smith JA, Turner MJ, Delay ML, Klenk EI, Sowders DP, Colbert RA. Endoplasmic reticulum stress and the unfolded protein response are linked to synergistic IFN-β induction via X-box binding protein 1. Eur J Immunol 2008;38:1194-1203.
-
(2008)
Eur J Immunol
, vol.38
, pp. 1194-1203
-
-
Smith, J.A.1
Turner, M.J.2
Delay, M.L.3
Klenk, E.I.4
Sowders, D.P.5
Colbert, R.A.6
-
107
-
-
77956917631
-
XBP-1 couples endoplasmic reticulum stress to augmented IFN-β induction via a cis-acting enhancer in macrophages
-
Zeng L, Liu Y-, Sha H, Chen H, Qi L, Smith JA. XBP-1 couples endoplasmic reticulum stress to augmented IFN-β induction via a cis-acting enhancer in macrophages. J Immunol 2010;185:2324-2330.
-
(2010)
J Immunol
, vol.185
, pp. 2324-2330
-
-
Zeng, L.1
Liu, Y.2
Sha, H.3
Chen, H.4
Qi, L.5
Smith, J.A.6
-
108
-
-
18744382408
-
Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1α
-
Marcu MG, Doyle M, Bertolotti A, Ron D, Hendershot L, Neckers L. Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1α. Mol Cell Biol 2002;22:8506-8513.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 8506-8513
-
-
Marcu, M.G.1
Doyle, M.2
Bertolotti, A.3
Ron, D.4
Hendershot, L.5
Neckers, L.6
-
109
-
-
61649113941
-
Prevalence of infectious pathogens in Crohn's disease
-
Knösel T, Schewe C, Petersen N, Dietel M, Petersen I. Prevalence of infectious pathogens in Crohn's disease. Pathol Res Pract 2009;205:223-230.
-
(2009)
Pathol Res Pract
, vol.205
, pp. 223-230
-
-
Knösel, T.1
Schewe, C.2
Petersen, N.3
Dietel, M.4
Petersen, I.5
-
110
-
-
34547879632
-
Search for evidence of recurring or persistent viruses in Crohn's disease
-
Van Kruiningen HJ, et al. Search for evidence of recurring or persistent viruses in Crohn's disease. APMIS 2007;115:962-968.
-
(2007)
APMIS
, vol.115
, pp. 962-968
-
-
Van Kruiningen, H.J.1
-
111
-
-
79952755799
-
Genome-virome interactions: examining the role of common viral infections in complex disease
-
Foxman EF, Iwasaki A. Genome-virome interactions: examining the role of common viral infections in complex disease. Nat Rev Microbiol 2011;9:254-264.
-
(2011)
Nat Rev Microbiol
, vol.9
, pp. 254-264
-
-
Foxman, E.F.1
Iwasaki, A.2
-
112
-
-
54849421128
-
Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant
-
Kuballa P, Huett A, Rioux JD, Daly MJ, Xavier RJ. Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant. PLoS ONE 2008;3:e3391.
-
(2008)
PLoS ONE
, vol.3
-
-
Kuballa, P.1
Huett, A.2
Rioux, J.D.3
Daly, M.J.4
Xavier, R.J.5
-
113
-
-
56249135538
-
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
-
Cadwell K, et al. A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature 2008;456:259-263.
-
(2008)
Nature
, vol.456
, pp. 259-263
-
-
Cadwell, K.1
-
114
-
-
61649114427
-
A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn's disease
-
Cadwell K, Patel KK, Komatsu M, Virgin HW IV, Stappenbeck TS. A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn's disease. Autophagy 2009;5:250-252.
-
(2009)
Autophagy
, vol.5
, pp. 250-252
-
-
Cadwell, K.1
Patel, K.K.2
Komatsu, M.3
Virgin IV, H.W.4
Stappenbeck, T.S.5
-
115
-
-
77953904042
-
Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine
-
Cadwell K, et al. Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine. Cell 2010;141:1135-1145.
-
(2010)
Cell
, vol.141
, pp. 1135-1145
-
-
Cadwell, K.1
-
116
-
-
48249147006
-
MDA-5 recognition of a murine norovirus
-
McCartney SA, Thackray LB, Gitlin L, Gilfillan S, Virgin HW, Colonna M. MDA-5 recognition of a murine norovirus. PLoS Pathog 2008;4:e1000108.
-
(2008)
PLoS Pathog
, vol.4
-
-
McCartney, S.A.1
Thackray, L.B.2
Gitlin, L.3
Gilfillan, S.4
Virgin, H.W.5
Colonna, M.6
-
117
-
-
73849121209
-
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
-
Travassos LH, et al. Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat Immunol 2010;11:55-62.
-
(2010)
Nat Immunol
, vol.11
, pp. 55-62
-
-
Travassos, L.H.1
-
118
-
-
73849151394
-
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
-
Cooney R, et al. NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. Nat Med 2010;16:90-97.
-
(2010)
Nat Med
, vol.16
, pp. 90-97
-
-
Cooney, R.1
-
119
-
-
77957682295
-
ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis
-
Homer CR, Richmond AL, Rebert NA, Achkar J, McDonald C. ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis. Gastroenterology 2010;139:1630-1641.
-
(2010)
Gastroenterology
, vol.139
, pp. 1630-1641
-
-
Homer, C.R.1
Richmond, A.L.2
Rebert, N.A.3
Achkar, J.4
McDonald, C.5
-
120
-
-
50249086073
-
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease
-
Kaser A, et al. XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease. Cell 2008;134:743-756.
-
(2008)
Cell
, vol.134
, pp. 743-756
-
-
Kaser, A.1
-
121
-
-
33748506089
-
Human IRGM induces autophagy to eliminate intracellular mycobacteria
-
Singh SB, Davis AS, Taylor GA, Deretic V. Human IRGM induces autophagy to eliminate intracellular mycobacteria. Science 2006;313:1438-1441.
-
(2006)
Science
, vol.313
, pp. 1438-1441
-
-
Singh, S.B.1
Davis, A.S.2
Taylor, G.A.3
Deretic, V.4
-
122
-
-
79952134938
-
A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease
-
Brest P, et al. A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease. Nat Genet 2011;43:242-245.
-
(2011)
Nat Genet
, vol.43
, pp. 242-245
-
-
Brest, P.1
-
123
-
-
78649833818
-
Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria
-
Singh SB, et al. Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria. Nature Cell Biol 2010;12:1154-1165.
-
(2010)
Nature Cell Biol
, vol.12
, pp. 1154-1165
-
-
Singh, S.B.1
-
124
-
-
0141884297
-
Decreased oxidative stress in patients with ulcerative colitis supplemented with fish oil ω-3 fatty acids
-
Barbosa DS, Cecchini R, El Kadri MZ, Rodríguez MAM, Burini RC, Dichi I. Decreased oxidative stress in patients with ulcerative colitis supplemented with fish oil ω-3 fatty acids. Nutrition 2003;19:837-842.
-
(2003)
Nutrition
, vol.19
, pp. 837-842
-
-
Barbosa, D.S.1
Cecchini, R.2
El Kadri, M.Z.3
Rodríguez, M.A.M.4
Burini, R.C.5
Dichi, I.6
-
125
-
-
0012169597
-
Differential mucosal expression of three superoxide dismutase isoforms in inflammatory bowel disease
-
Kruidenier L, et al. Differential mucosal expression of three superoxide dismutase isoforms in inflammatory bowel disease. J Pathol 2003;201:7-16.
-
(2003)
J Pathol
, vol.201
, pp. 7-16
-
-
Kruidenier, L.1
-
126
-
-
74049155086
-
Mitochondrial dysfunction, persistent oxidative damage, and catalase inhibition in immune cells of naïve and treated Crohn's disease
-
Beltŕan B, et al. Mitochondrial dysfunction, persistent oxidative damage, and catalase inhibition in immune cells of naïve and treated Crohn's disease. Inflammatory Bowel Dis 2010;16:76-86.
-
(2010)
Inflammatory Bowel Dis
, vol.16
, pp. 76-86
-
-
Beltŕan, B.1
-
127
-
-
43449128404
-
Glutathione peroxidase 2 and aquaporin 8 as new markers for colonic inflammation in experimental colitis and inflammatory bowel diseases: An important role for H2O2?
-
Te Velde AA, Pronk I, De Kort F, Stokkers PCF. Glutathione peroxidase 2 and aquaporin 8 as new markers for colonic inflammation in experimental colitis and inflammatory bowel diseases: An important role for H2O2? Eur J Gastroenterol Hepatol 2008;20:555-560.
-
(2008)
Eur J Gastroenterol Hepatol
, vol.20
, pp. 555-560
-
-
Te Velde, A.A.1
Pronk, I.2
De Kort, F.3
Stokkers, P.C.F.4
-
129
-
-
79955532516
-
TLR signalling augments macrophage bactericidal activity through mitochondrial ROS
-
West AP, et al. TLR signalling augments macrophage bactericidal activity through mitochondrial ROS. Nature 2011;472:476-480.
-
(2011)
Nature
, vol.472
, pp. 476-480
-
-
West, A.P.1
|