-
1
-
-
0029954214
-
Insulin-dependent diabetes mellitus
-
Tisch R, McDevitt H: Insulin-dependent diabetes mellitus. Cell 8:291-297, 1996
-
(1996)
Cell
, vol.8
, pp. 291-297
-
-
Tisch, R.1
McDevitt, H.2
-
2
-
-
0035668779
-
A choice of death: The signal-transduction of immune-mediated beta-cell apoptosis
-
Eizirik DL, Mandrup-Poulsen T: A choice of death: the signal-transduction of immune-mediated beta-cell apoptosis. Diabetologia 44:2115-2133, 2000
-
(2000)
Diabetologia
, vol.44
, pp. 2115-2133
-
-
Eizirik, D.L.1
Mandrup-Poulsen, T.2
-
3
-
-
0032932324
-
β-cell destruction in NOD mice correlates with Fas (CD95) expression on beta-cell and proinflammatory cytokine expression in islets
-
Suarez-Pinzon W, Sorensen O, Bleackley RC, Elliott JF, Rajotte RV, Rabinovitch A: β-cell destruction in NOD mice correlates with Fas (CD95) expression on beta-cell and proinflammatory cytokine expression in islets. Diabetes 48:21-28, 1999
-
(1999)
Diabetes
, vol.48
, pp. 21-28
-
-
Suarez-Pinzon, W.1
Sorensen, O.2
Bleackley, R.C.3
Elliott, J.F.4
Rajotte, R.V.5
Rabinovitch, A.6
-
4
-
-
33846818313
-
Macrophages and dendritic cells infiltrating islets with or without beta- cells produce tumour necrosis factor-alpha in patients with recent-onset type 1 diabetes
-
Uno S, Imagawa A, Okita K, Sayama K, Moriwaki M, Iwahashi H, Yamagata K, Tamura S, Matsuzawa Y, Hanafusa T, Miyagawa J, Shimomura I: Macrophages and dendritic cells infiltrating islets with or without beta- cells produce tumour necrosis factor-alpha in patients with recent-onset type 1 diabetes. Diabetologia 50:596- 601, 2007
-
(2007)
Diabetologia
, vol.50
, pp. 596-601
-
-
Uno, S.1
Imagawa, A.2
Okita, K.3
Sayama, K.4
Moriwaki, M.5
Iwahashi, H.6
Yamagata, K.7
Tamura, S.8
Matsuzawa, Y.9
Hanafusa, T.10
Miyagawa, J.11
Shimomura, I.12
-
5
-
-
0029932759
-
Interleukin-1beta-induced ceramide and diacylglycerol generation may lead to activation of the c-Jun-NH2-terminal kinase and the transcription factor ATF2 in the insulin-producing cell line RINm5F
-
Welsh N: Interleukin-1beta-induced ceramide and diacylglycerol generation may lead to activation of the c-Jun-NH2-terminal kinase and the transcription factor ATF2 in the insulin-producing cell line RINm5F. J Biol Chem 271:8307-8312, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 8307-8312
-
-
Welsh, N.1
-
6
-
-
0032510838
-
Interleukin-1β-induced rat pancreatic islet NO synthesis requires both the p38 and extracellular-signal regulated kinase 1/2 mitogen-activated protein kinases
-
Larsen CM, Wadt KA, Juhl LF, Andersen HU, Karlsen AE, Su MS, Seedorf K, Shapiro L, Dinarello CA, Mandrup-Poulsen T: Interleukin-1β-induced rat pancreatic islet NO synthesis requires both the p38 and extracellular-signal regulated kinase 1/2 mitogen-activated protein kinases. J Biol Chem 273:15294-15300, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 15294-15300
-
-
Larsen, C.M.1
Wadt, K.A.2
Juhl, L.F.3
Andersen, H.U.4
Karlsen, A.E.5
Su, M.S.6
Seedorf, K.7
Shapiro, L.8
Dinarello, C.A.9
Mandrup-Poulsen, T.10
-
7
-
-
0035152487
-
Cell-permeable peptide inhibitors of JNK: Novel blockers of β-cell death
-
Bonny C, Oberson A, Negri S, Sauser C, Schorderet DF: Cell-permeable peptide inhibitors of JNK: novel blockers of β-cell death. Diabetes 50:77-82, 2001
-
(2001)
Diabetes
, vol.50
, pp. 77-82
-
-
Bonny, C.1
Oberson, A.2
Negri, S.3
Sauser, C.4
Schorderet, D.F.5
-
8
-
-
0035877087
-
Role of p38 MAPK in cytokine-induced rat islet cell apoptosis
-
Saldeen J, Lee JC, Welsh N: Role of p38 MAPK in cytokine-induced rat islet cell apoptosis. Biochem Pharmacol 61:561-569, 2001
-
(2001)
Biochem Pharmacol
, vol.61
, pp. 561-569
-
-
Saldeen, J.1
Lee, J.C.2
Welsh, N.3
-
9
-
-
0029665049
-
Cytokines activate the nuclear factor kB (NF-κB) and induces nitric oxide production in human pancreatic islets
-
Flodstrom M, Welsh N, Eizirik DL: Cytokines activate the nuclear factor kB (NF-κB) and induces nitric oxide production in human pancreatic islets. FEBS Lett 385:4-6, 1996
-
(1996)
FEBS Lett
, vol.385
, pp. 4-6
-
-
Flodstrom, M.1
Welsh, N.2
Eizirik, D.L.3
-
10
-
-
0028167680
-
Interleukin-1β induced activation of NF-κB in insulin producing RIN5mF cells is prevented by the protease inhibitor tosyllysine chloromethyl ketone
-
Saldeen J, Welsh N: Interleukin-1β induced activation of NF-κB in insulin producing RIN5mF cells is prevented by the protease inhibitor tosyllysine chloromethyl ketone. Biochem Biophys Res Commun 203:149-155, 1994
-
(1994)
Biochem Biophys Res Commun
, vol.203
, pp. 149-155
-
-
Saldeen, J.1
Welsh, N.2
-
11
-
-
0037032817
-
Mitogen-activated protein kinase pathways mediated by ERK, JNK and p38 protein kinases
-
Johnson GL, Lapadat R: Mitogen-activated protein kinase pathways mediated by ERK, JNK and p38 protein kinases. Science 298:1911-1919, 2002
-
(2002)
Science
, vol.298
, pp. 1911-1919
-
-
Johnson, G.L.1
Lapadat, R.2
-
12
-
-
0031954631
-
MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis
-
Widmann C, Gerwins P, Johnson NL, Jarpe MB, Johnson GL: MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis. Mol Cell Biol 18:2416-2429, 1998
-
(1998)
Mol Cell Biol
, vol.18
, pp. 2416-2429
-
-
Widmann, C.1
Gerwins, P.2
Johnson, N.L.3
Jarpe, M.B.4
Johnson, G.L.5
-
13
-
-
0032697485
-
Tumor necrosis factor-related apoptosis- inducing ligand receptors signal NF-kappaB and JNK activation and apoptosis through distinct pathways
-
Hu WH, Johnson H, Shu HB: Tumor necrosis factor-related apoptosis- inducing ligand receptors signal NF-kappaB and JNK activation and apoptosis through distinct pathways. J Biol Chem 274:30603-30610, 1999
-
(1999)
J Biol Chem
, vol.274
, pp. 30603-30610
-
-
Hu, W.H.1
Johnson, H.2
Shu, H.B.3
-
14
-
-
0032557678
-
Induction of cyclooxygenase-2 by the activated MEKK1 → SEK1/MKK4 → p38 mitogen-activated protein kinase pathway
-
Guan Z, Buckman SY, Pentland AP, Templeton DJ, Morrison AR: Induction of cyclooxygenase-2 by the activated MEKK1 → SEK1/MKK4 → p38 mitogen-activated protein kinase pathway. J Biol Chem 273:12901-12908, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 12901-12908
-
-
Guan, Z.1
Buckman, S.Y.2
Pentland, A.P.3
Templeton, D.J.4
Morrison, A.R.5
-
15
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
Davis RJ: Signal transduction by the JNK group of MAP kinases. Cell 103:239-252, 2000
-
(2000)
Cell
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
16
-
-
0036279167
-
The PHD domain of MEKK1 acts as an E3 ubiquitin ligase and mediates ubiquitination and degradation of ERK1/2
-
Lu Z, Xu S, Joazeiro C, Cobb CH, Hunter T: The PHD domain of MEKK1 acts as an E3 ubiquitin ligase and mediates ubiquitination and degradation of ERK1/2. Mol Cell 9:945-956, 2002
-
(2002)
Mol Cell
, vol.9
, pp. 945-956
-
-
Lu, Z.1
Xu, S.2
Joazeiro, C.3
Cobb, C.H.4
Hunter, T.5
-
17
-
-
0036009115
-
NF-kappaB at the crossroads of life and death
-
Karin M, Lin A: NF-kappaB at the crossroads of life and death. Nat Immunol 3:221-227, 2002
-
(2002)
Nat Immunol
, vol.3
, pp. 221-227
-
-
Karin, M.1
Lin, A.2
-
18
-
-
0035488777
-
Inhibition of cytokine-induced NF-κB activation by adenovirus- mediated expression of a NF-κB super-repressor prevents β-cell apoptosis
-
Heimberg H, Heremans Y, Jobin C, Leemans R, Cardozo AK, Darville M, Eizirik DL: Inhibition of cytokine-induced NF-κB activation by adenovirus- mediated expression of a NF-κB super-repressor prevents β-cell apoptosis. Diabetes 50:2219-2224, 2001
-
(2001)
Diabetes
, vol.50
, pp. 2219-2224
-
-
Heimberg, H.1
Heremans, Y.2
Jobin, C.3
Leemans, R.4
Cardozo, A.K.5
Darville, M.6
Eizirik, D.L.7
-
19
-
-
33645518035
-
Conditional and specific NF-kB blockade protects pancreatic beta cells from diabetogenic agents
-
Eldor R, Yeffet A, Baum K, Doviner V, Amar D, Ben-Neriah Y, Christofori G, Peled A, Carel JC, Boitard C, Klein T, Serup P, Eizirik DL, Melloul D: Conditional and specific NF-kB blockade protects pancreatic beta cells from diabetogenic agents. Proc Natl Acad SciUSA103:5072-5077, 2006
-
(2006)
Proc Natl Acad SciUSA
, vol.103
, pp. 5072-5077
-
-
Eldor, R.1
Yeffet, A.2
Baum, K.3
Doviner, V.4
Amar, D.5
Ben-Neriah, Y.6
Christofori, G.7
Peled, A.8
Carel, J.C.9
Boitard, C.10
Klein, T.11
Serup, P.12
Eizirik, D.L.13
Melloul, D.14
-
20
-
-
0029879315
-
Interaction between c-Rel and the mitogen-activated protein kinase kinase kinase 1 signaling cascade in mediating kappaB enhancer activation
-
Meyer CF, Wang X, Widmann C, Chang C, Templeton D, Tan TH: Interaction between c-Rel and the mitogen-activated protein kinase kinase kinase 1 signaling cascade in mediating kappaB enhancer activation. J Biol Chem 271:8971-8976, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 8971-8976
-
-
Meyer, C.F.1
Wang, X.2
Widmann, C.3
Chang, C.4
Templeton, D.5
Tan, T.H.6
-
21
-
-
44249094869
-
The MAPK kinase kinase-1 is essential for stress-induced pancreatic islet cell death
-
In press
-
Mokhtari D, Myers JW, Welsh N: The MAPK kinase kinase-1 is essential for stress-induced pancreatic islet cell death. Endocrinology. In press
-
Endocrinology
-
-
Mokhtari, D.1
Myers, J.W.2
Welsh, N.3
-
22
-
-
25144524025
-
Silencing gene expression with dicer-generated siRNA pools
-
Myers JW, Ferrell JE: Silencing gene expression with dicer-generated siRNA pools. Methods Mol Biol 309:93-96, 2005
-
(2005)
Methods Mol Biol
, vol.309
, pp. 93-96
-
-
Myers, J.W.1
Ferrell, J.E.2
-
23
-
-
0036872511
-
Overexpression of the Shb SH2 domain- protein in insulin-producing cells leads to altered signaling through the IRS-1 and IRS-2 proteins
-
Welsh N, Makeeva N, Welsh M: Overexpression of the Shb SH2 domain- protein in insulin-producing cells leads to altered signaling through the IRS-1 and IRS-2 proteins. Mol Med 8:695-704, 2002
-
(2002)
Mol Med
, vol.8
, pp. 695-704
-
-
Welsh, N.1
Makeeva, N.2
Welsh, M.3
-
24
-
-
0031051303
-
Regulation of the activity of MEK kinase 1 (MEKK1) by autophosphorylation within the kinase activation domain
-
Deak JC, Templeton DJ: Regulation of the activity of MEK kinase 1 (MEKK1) by autophosphorylation within the kinase activation domain. Biochem J 322:185-192, 1997
-
(1997)
Biochem J
, vol.322
, pp. 185-192
-
-
Deak, J.C.1
Templeton, D.J.2
-
25
-
-
34347378432
-
Lipofection of insulin-producing RINm5F cells: Methodological improvements
-
Barbu A, Welsh N: Lipofection of insulin-producing RINm5F cells: methodological improvements. J Liposome Res 17:49 - 62, 2007
-
(2007)
J Liposome Res
, vol.17
, pp. 49-62
-
-
Barbu, A.1
Welsh, N.2
-
26
-
-
22144439750
-
siRNA produced by recombinant dicer mediates efficient gene silencing in islet cells
-
Hagerkvist R, Mokhtari D, Myers J, Tengholm A, Welsh N: siRNA produced by recombinant dicer mediates efficient gene silencing in islet cells. Ann N Y Acad Sci 1040:695-704, 2005
-
(2005)
Ann N Y Acad Sci
, vol.1040
, pp. 695-704
-
-
Hagerkvist, R.1
Mokhtari, D.2
Myers, J.3
Tengholm, A.4
Welsh, N.5
-
27
-
-
0028049833
-
Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury
-
Eizirik DL, Pipeleers DG, Ling Z, Welsh N, Hellerstrom C, Andersson A: Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury. Proc Natl Acad SciUSA91:9253-9256, 1994
-
(1994)
Proc Natl Acad SciUSA
, vol.91
, pp. 9253-9256
-
-
Eizirik, D.L.1
Pipeleers, D.G.2
Ling, Z.3
Welsh, N.4
Hellerstrom, C.5
Andersson, A.6
-
28
-
-
0034761792
-
Synergistic induction of matrix metalloproteinase 1 by interleukin-1alpha and oncostatin M in human chondrocytes involves signal transducer and activator of transcription and activator protein 1 transcription factors via a novel mechanism
-
Catterall JB, Carrere S, Koshy PJ, Degnan BA, Shingleton WD, Brinckerhoff CE, Rutter J, Cawston TE, Rowan AD: Synergistic induction of matrix metalloproteinase 1 by interleukin-1alpha and oncostatin M in human chondrocytes involves signal transducer and activator of transcription and activator protein 1 transcription factors via a novel mechanism. Arthritis Rheum 44:2296-2310, 2001
-
(2001)
Arthritis Rheum
, vol.44
, pp. 2296-2310
-
-
Catterall, J.B.1
Carrere, S.2
Koshy, P.J.3
Degnan, B.A.4
Shingleton, W.D.5
Brinckerhoff, C.E.6
Rutter, J.7
Cawston, T.E.8
Rowan, A.D.9
-
29
-
-
18844457095
-
Mechanisms of type-1 and type-II interferon-mediated signalling
-
Platanias LC: Mechanisms of type-1 and type-II interferon-mediated signalling. Nat Rev Immunol 5:375-386, 2005
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 375-386
-
-
Platanias, L.C.1
-
30
-
-
0346101742
-
Fibrilogenic amylin evokes islet-beta-cell apoptosis through linked activation ofa caspase cascade and JNK1
-
Zhang S, Liu J, Dragunow M, Cooper GJ: Fibrilogenic amylin evokes islet-beta-cell apoptosis through linked activation ofa caspase cascade and JNK1. J Biol Chem 278:52810-52819, 2003
-
(2003)
J Biol Chem
, vol.278
, pp. 52810-52819
-
-
Zhang, S.1
Liu, J.2
Dragunow, M.3
Cooper, G.J.4
-
31
-
-
7044249537
-
Intracellular stress signaling pathways activated during human islet preparation and following acute cytokine exposure
-
31
-
31.Abdelli S, Ansite J, Roduit R, Borsello T, Matsumoto I, Sawada T, Allaman-Pillet N, Henry H, Beckman JS, Hering BJ, Bonny C: Intracellular stress signaling pathways activated during human islet preparation and following acute cytokine exposure. Diabetes 53:2815-2823, 2004
-
(2004)
Diabetes
, vol.53
, pp. 2815-2823
-
-
Abdelli, S.1
Ansite, J.2
Roduit, R.3
Borsello, T.4
Matsumoto, I.5
Sawada, T.6
Allaman-Pillet, N.7
Henry, H.8
Beckman, J.S.9
Hering, B.J.10
Bonny, C.11
-
32
-
-
34347392053
-
Regulation of the JNK pathway by TGF-beta activated kinase 1 in rheumatoid arthritis synoviocytes
-
Hammaker DR, Boyle DL, Inoue T, Firestein GS: Regulation of the JNK pathway by TGF-beta activated kinase 1 in rheumatoid arthritis synoviocytes. Arthritis Res Ther 9:R57, 2007
-
(2007)
Arthritis Res Ther
, vol.9
-
-
Hammaker, D.R.1
Boyle, D.L.2
Inoue, T.3
Firestein, G.S.4
-
33
-
-
1642444091
-
Regulation of c-Jun N-terminal kinase by MEKK-2 and mitogen-activated protein kinase kinase kinases in rheumatoid arthritis
-
Hammaker DR, Boyle DL, Chabaud-Riou M, Firestein GS: Regulation of c-Jun N-terminal kinase by MEKK-2 and mitogen-activated protein kinase kinase kinases in rheumatoid arthritis. J Immunol 172:1612-1618, 2004
-
(2004)
J Immunol
, vol.172
, pp. 1612-1618
-
-
Hammaker, D.R.1
Boyle, D.L.2
Chabaud-Riou, M.3
Firestein, G.S.4
-
34
-
-
0034073381
-
Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex
-
Hehner SP, Hofmann TG, Ushmorov A, Dienz O, Wing-Lan Leung I, Lassam N, Scheidereit C, Droge W, Schmitz ML: Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex. Mol Cell Biol 20:2556-2568, 2000
-
(2000)
Mol Cell Biol
, vol.20
, pp. 2556-2568
-
-
Hehner, S.P.1
Hofmann, T.G.2
Ushmorov, A.3
Dienz, O.4
Wing-Lan Leung, I.5
Lassam, N.6
Scheidereit, C.7
Droge, W.8
Schmitz, M.L.9
-
35
-
-
0034625170
-
MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration
-
Xia Y, Makris C, Su B, Li E, Yang J, Nemerow GR, Karin M: MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration. Proc Natl Acad SciUSA9:5243-5248, 2000
-
(2000)
Proc Natl Acad SciUSA
, vol.9
, pp. 5243-5248
-
-
Xia, Y.1
Makris, C.2
Su, B.3
Li, E.4
Yang, J.5
Nemerow, G.R.6
Karin, M.7
-
36
-
-
0031597368
-
Coordinate regulation of IκB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-κB inducing kinase
-
Nemoto S, DiDonato JA, Lin A: Coordinate regulation of IκB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-κB inducing kinase. Mol Cell Biol 18:3537-3542, 1998
-
(1998)
Mol Cell Biol
, vol.18
, pp. 3537-3542
-
-
Nemoto, S.1
DiDonato, J.A.2
Lin, A.3
-
37
-
-
17644397574
-
Tumor necrosis factor alpha-induced desumoylation and cytoplasmic translocation of homeodomain-interacting protein kinase 1 are critical for apoptosis signal- regulating kinase 1-JNK/p38 activation
-
Li X, Zhang R, Luo D, Park SJ, Wang Q, Kim Y, Min W: Tumor necrosis factor alpha-induced desumoylation and cytoplasmic translocation of homeodomain-interacting protein kinase 1 are critical for apoptosis signal- regulating kinase 1-JNK/p38 activation. J Biol Chem 280:15061-15070, 2005
-
(2005)
J Biol Chem
, vol.280
, pp. 15061-15070
-
-
Li, X.1
Zhang, R.2
Luo, D.3
Park, S.J.4
Wang, Q.5
Kim, Y.6
Min, W.7
-
38
-
-
0028109668
-
Human pancreatic islet beta-cell destruction by cytokines is independent of nitric oxide production
-
Rabinovitch A, Suarez-Pinzon WL, Strynadka K, Schulz R, Lakey JR, Warnock GL, Rajotte RV: Human pancreatic islet beta-cell destruction by cytokines is independent of nitric oxide production. J Clin Endocrinol Metab 79:1058-1062, 1994
-
(1994)
J Clin Endocrinol Metab
, vol.79
, pp. 1058-1062
-
-
Rabinovitch, A.1
Suarez-Pinzon, W.L.2
Strynadka, K.3
Schulz, R.4
Lakey, J.R.5
Warnock, G.L.6
Rajotte, R.V.7
-
39
-
-
0035124874
-
β-cell apoptosis and defense mechanisms: Lessons from type 1 diabetes
-
Eizirik DL, Darville MI: β-cell apoptosis and defense mechanisms: lessons from type 1 diabetes. Diabetes 50 (Suppl. 1):S64-S69, 2001
-
(2001)
Diabetes
, vol.50
, Issue.SUPPL. 1
-
-
Eizirik, D.L.1
Darville, M.I.2
-
40
-
-
0033850451
-
The c-Jun amino- terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic beta-cell
-
Ammendrup A, Maillard A, Nielsen K, Aabenhus Anderssen N, Serup P, Dragsbaek Madsen O, Mandrup-Poulsen T, Bonny C: The c-Jun amino- terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic beta-cell. Diabetes 49:1468-1476, 2000
-
(2000)
Diabetes
, vol.49
, pp. 1468-1476
-
-
Ammendrup, A.1
Maillard, A.2
Nielsen, K.3
Aabenhus Anderssen, N.4
Serup, P.5
Dragsbaek Madsen, O.6
Mandrup-Poulsen, T.7
Bonny, C.8
-
41
-
-
34447128957
-
Inhibition of MafA transcriptional activity and human insulin gene transcription by interleukin-1β and mitogen-activated protein kinase kinase kinase in pancreatic islet beta cells
-
Oetjen E, Blume R, Cierny I, Schlag C, Kutschenko A, Krätzner R, Stein R, Knepel W: Inhibition of MafA transcriptional activity and human insulin gene transcription by interleukin-1β and mitogen-activated protein kinase kinase kinase in pancreatic islet beta cells. Diabetologia 50:1678-1687, 2007
-
(2007)
Diabetologia
, vol.50
, pp. 1678-1687
-
-
Oetjen, E.1
Blume, R.2
Cierny, I.3
Schlag, C.4
Kutschenko, A.5
Krätzner, R.6
Stein, R.7
Knepel, W.8
-
42
-
-
0028568217
-
Differential activation of ERK and JNK mitogen- activated protein kinases by Raf-1 and MEKK
-
Minden A, Lin A, McMahon M, Lange-Carter C, Derijard B, Davis RJ, Johnson GL, Karin M: Differential activation of ERK and JNK mitogen- activated protein kinases by Raf-1 and MEKK. Science 266:1719-1723,1994
-
(1994)
Science
, vol.266
, pp. 1719-1723
-
-
Minden, A.1
Lin, A.2
McMahon, M.3
Lange-Carter, C.4
Derijard, B.5
Davis, R.J.6
Johnson, G.L.7
Karin, M.8
-
43
-
-
37549057010
-
TAB1{alpha}, but not TAB1{beta}, mediates cytokine-induced p38 MAPK phosphorylation and cell death in insulin producing cells
-
Makeeva N, Roomans GM, Myers JW, Welsh N: TAB1{alpha}, but not TAB1{beta}, mediates cytokine-induced p38 MAPK phosphorylation and cell death in insulin producing cells. Endocrinology 149:302-309, 2008
-
(2008)
Endocrinology
, vol.149
, pp. 302-309
-
-
Makeeva, N.1
Roomans, G.M.2
Myers, J.W.3
Welsh, N.4
-
44
-
-
30044444610
-
Role of MKK3 and p38 MAPK in cytokine-induced death of insulin producing cells
-
Makeeva N, Myers JW, Welsh N: Role of MKK3 and p38 MAPK in cytokine-induced death of insulin producing cells. Biochem J 393:129-139, 2006
-
(2006)
Biochem J
, vol.393
, pp. 129-139
-
-
Makeeva, N.1
Myers, J.W.2
Welsh, N.3
-
45
-
-
0030910706
-
Identification of two essential threonine residues in the catalytic domain of Mekk1: Indirect activation by Pak3 and protein kinase C
-
Siow YL, Kalmar GB, Sanghera JS, Tai G, Oh SS, Pelch SL: Identification of two essential threonine residues in the catalytic domain of Mekk1: indirect activation by Pak3 and protein kinase C. J Biol Chem 272:7586-7594, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 7586-7594
-
-
Siow, Y.L.1
Kalmar, G.B.2
Sanghera, J.S.3
Tai, G.4
Oh, S.S.5
Pelch, S.L.6
-
46
-
-
0030875602
-
MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42
-
Fanger GR, Johnson NL, Johnson GL: MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42. EMBO J 16:4961-4972, 1997
-
(1997)
EMBO J
, vol.16
, pp. 4961-4972
-
-
Fanger, G.R.1
Johnson, N.L.2
Johnson, G.L.3
-
47
-
-
0035920178
-
Role of receptor-interacting protein in tumor necrosis factor-alpha-dependent MEKK1 activation
-
Kim JW, Joe CO, Choi EJ: Role of receptor-interacting protein in tumor necrosis factor-alpha-dependent MEKK1 activation. J Biol Chem 276: 27064-27070, 2001
-
(2001)
J Biol Chem
, vol.276
, pp. 27064-27070
-
-
Kim, J.W.1
Joe, C.O.2
Choi, E.J.3
-
48
-
-
0036143713
-
Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adaptor protein TRAF2
-
Chadee DN, Yuasa T, Kyriakis JM: Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adaptor protein TRAF2. Mol Cell Biol 22:737-749, 2002
-
(2002)
Mol Cell Biol
, vol.22
, pp. 737-749
-
-
Chadee, D.N.1
Yuasa, T.2
Kyriakis, J.M.3
-
49
-
-
11144300244
-
MEKK1 transduces activin signals in keratinocytes to induce actin stress fiber formation and migration
-
Zhang L, Deng M, Parthasarathy R, Wang L, Mongan M, Molkentin JD, Zheng Y, Xia Y: MEKK1 transduces activin signals in keratinocytes to induce actin stress fiber formation and migration. Mol Cell Biol 25:60-65, 2005
-
(2005)
Mol Cell Biol
, vol.25
, pp. 60-65
-
-
Zhang, L.1
Deng, M.2
Parthasarathy, R.3
Wang, L.4
Mongan, M.5
Molkentin, J.D.6
Zheng, Y.7
Xia, Y.8
-
50
-
-
2542579529
-
Interaction and association analysis of a type 1 diabetes susceptibility locus on chromosome 5q11-q13 and the 7q32 chromosomal region in Scandinavian families
-
Holm P, Rydlander B, Luthman H, Kockum I: Interaction and association analysis of a type 1 diabetes susceptibility locus on chromosome 5q11-q13 and the 7q32 chromosomal region in Scandinavian families. Diabetes 53:1584-1591, 2004
-
(2004)
Diabetes
, vol.53
, pp. 1584-1591
-
-
Holm, P.1
Rydlander, B.2
Luthman, H.3
Kockum, I.4
|