-
1
-
-
55149113944
-
Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites
-
Saenz SA, Taylor BC, Artis D. Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites. Immunol Rev 2008;226:172-190.
-
(2008)
Immunol Rev
, vol.226
, pp. 172-190
-
-
Saenz, S.A.1
Taylor, B.C.2
Artis, D.3
-
2
-
-
35348902058
-
Cooperative effects of rhinovirus and TNF-{alpha} on airway epithelial cell chemokine expression
-
Newcomb DC, Sajjan US, Nagarkar DR, Goldsmith AM, Bentley JK, Hershenson MB. Cooperative effects of rhinovirus and TNF-{alpha} on airway epithelial cell chemokine expression. Am J Physiol Lung Cell Mol Physiol 2007;293:L1021-L1028.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.293
-
-
Newcomb, D.C.1
Sajjan, U.S.2
Nagarkar, D.R.3
Goldsmith, A.M.4
Bentley, J.K.5
Hershenson, M.B.6
-
3
-
-
35348931194
-
-
National surveillance for asthma - United States, 1980-2004. MMWR Surveill Summ.
-
Jeanne EM, et al. National surveillance for asthma - United States, 1980-2004. MMWR Surveill Summ 2007;56:1-54.
-
(2007)
, vol.56
, pp. 1-54
-
-
Jeanne, E.M.1
-
4
-
-
0023223039
-
National trends in the morbidity and mortality of asthma in the US. Prevalence, hospitalization and death from asthma over two decades: 1965-1984
-
Evans R 3rd, et al. National trends in the morbidity and mortality of asthma in the US. Prevalence, hospitalization and death from asthma over two decades: 1965-1984. Chest 1987;91:65S-74S.
-
(1987)
Chest
, vol.91
-
-
Evans 3rd, R.1
-
5
-
-
0032562336
-
-
National surveillance for asthma - United States, 1960-1995. MMWR Surveill Summ.
-
Mannino DM, Homa DM, Pertowski CA National surveillance for asthma - United States, 1960-1995. MMWR Surveill Summ 1998;47:1-27.
-
(1998)
, vol.47
, pp. 1-27
-
-
Mannino, D.M.1
Homa, D.M.2
Pertowski, C.A.3
-
6
-
-
0037192906
-
-
National surveillance for asthma - United States, 1980-1999. MMWR Surveill Summ.
-
Mannino DM, Homa DM, Akinbami LJ, Moorman JE, Gwynn C, Redd SC National surveillance for asthma - United States, 1980-1999. MMWR Surveill Summ 2002;51:1-13.
-
(2002)
, vol.51
, pp. 1-13
-
-
Mannino, D.M.1
Homa, D.M.2
Akinbami, L.J.3
Moorman, J.E.4
Gwynn, C.5
Redd, S.C.6
-
7
-
-
0003427756
-
-
US Department of Health and Human Services. Washington, DC: US Government Printing Office
-
US Department of Health and Human Services. Healthy People 2010: Respiratory Diseases [Goal 24]. Washington, DC: US Government Printing Office, 2000.
-
(2000)
Healthy People 2010: Respiratory Diseases [Goal 24]
-
-
-
8
-
-
77950350422
-
Asthma and allergic inflammation
-
Locksley RM. Asthma and allergic inflammation. Cell 2010;140:777-783.
-
(2010)
Cell
, vol.140
, pp. 777-783
-
-
Locksley, R.M.1
-
9
-
-
77953794345
-
The many paths to asthma: phenotype shaped by innate and adaptive immunity
-
Kim HY, DeKruyff RH, Umetsu DT. The many paths to asthma: phenotype shaped by innate and adaptive immunity. Nat Immunol 2010;11:577-584.
-
(2010)
Nat Immunol
, vol.11
, pp. 577-584
-
-
Kim, H.Y.1
DeKruyff, R.H.2
Umetsu, D.T.3
-
10
-
-
18244405108
-
IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo
-
Fort MM, et al. IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo. Immunity 2001;15:985-995.
-
(2001)
Immunity
, vol.15
, pp. 985-995
-
-
Fort, M.M.1
-
11
-
-
75749122181
-
Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells
-
Moro K, et al. Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells. Nature 2009;463:540-544.
-
(2009)
Nature
, vol.463
, pp. 540-544
-
-
Moro, K.1
-
12
-
-
77954926597
-
Systemically dispersed innate IL-13-expressing cells in type 2 immunity
-
Price AE, et al. Systemically dispersed innate IL-13-expressing cells in type 2 immunity. Proc Natl Acad Sci USA 2010;107:11489-11494.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 11489-11494
-
-
Price, A.E.1
-
13
-
-
0032545433
-
Requirement for IL-13 independently of IL-4 in experimental asthma
-
Grunig G, et al. Requirement for IL-13 independently of IL-4 in experimental asthma. Science 1998;282:2261-2263.
-
(1998)
Science
, vol.282
, pp. 2261-2263
-
-
Grunig, G.1
-
14
-
-
0030922389
-
Elevated expression of messenger ribonucleic acid encoding IL-13 in the bronchial mucosa of atopic and nonatopic subjects with asthma
-
Humbert M, et al. Elevated expression of messenger ribonucleic acid encoding IL-13 in the bronchial mucosa of atopic and nonatopic subjects with asthma. J Allergy Clin Immunol 1997;99:657-665.
-
(1997)
J Allergy Clin Immunol
, vol.99
, pp. 657-665
-
-
Humbert, M.1
-
15
-
-
0032545213
-
Interleukin-13: central mediator of allergic asthma
-
Wills-Karp M, et al. Interleukin-13: central mediator of allergic asthma. Science 1998;282:2258-2261.
-
(1998)
Science
, vol.282
, pp. 2258-2261
-
-
Wills-Karp, M.1
-
16
-
-
0035009330
-
IL-13 induces mucin production by stimulating epidermal growth factor receptors and by activating neutrophils
-
Shim JJ, et al. IL-13 induces mucin production by stimulating epidermal growth factor receptors and by activating neutrophils. Am J Physiol Lung Cell Mol Physiol 2001;280:L134-L140.
-
(2001)
Am J Physiol Lung Cell Mol Physiol
, vol.280
-
-
Shim, J.J.1
-
17
-
-
0033560126
-
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
-
Zhu Z, et al. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest 1999;103:779-788.
-
(1999)
J Clin Invest
, vol.103
, pp. 779-788
-
-
Zhu, Z.1
-
18
-
-
0036083817
-
Role of IL-4, IL-13, and STAT6 in inflammation-induced hypercontractility of murine smooth muscle cells
-
Akiho H, Blennerhassett P, Deng Y, Collins SM. Role of IL-4, IL-13, and STAT6 in inflammation-induced hypercontractility of murine smooth muscle cells. Am J Physiol Gastrointest Liver Physiol 2002;282:G226-G232.
-
(2002)
Am J Physiol Gastrointest Liver Physiol
, vol.282
-
-
Akiho, H.1
Blennerhassett, P.2
Deng, Y.3
Collins, S.M.4
-
19
-
-
13644257561
-
IL-13 may mediate allergen-induced hyperresponsiveness independently of IL-5 or eotaxin by effects on airway smooth muscle
-
Eum SY, Maghni K, Tolloczko B, Eidelman DH, Martin JG. IL-13 may mediate allergen-induced hyperresponsiveness independently of IL-5 or eotaxin by effects on airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2005;288:L576-L584.
-
(2005)
Am J Physiol Lung Cell Mol Physiol
, vol.288
-
-
Eum, S.Y.1
Maghni, K.2
Tolloczko, B.3
Eidelman, D.H.4
Martin, J.G.5
-
20
-
-
0036088040
-
IL-13-dependent autocrine signaling mediates altered responsiveness of IgE-sensitized airway smooth muscle
-
Grunstein MM, et al. IL-13-dependent autocrine signaling mediates altered responsiveness of IgE-sensitized airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2002;282:L520-L528.
-
(2002)
Am J Physiol Lung Cell Mol Physiol
, vol.282
-
-
Grunstein, M.M.1
-
21
-
-
1642545168
-
IL-13 enhances agonist-evoked calcium signals and contractile responses in airway smooth muscle
-
Tliba O, et al. IL-13 enhances agonist-evoked calcium signals and contractile responses in airway smooth muscle. Br J Pharmacol 2003;140:1159-1162.
-
(2003)
Br J Pharmacol
, vol.140
, pp. 1159-1162
-
-
Tliba, O.1
-
22
-
-
0038404961
-
CysLT1 receptor upregulation by TGF-beta and IL-13 is associated with bronchial smooth muscle cell proliferation in response to LTD4
-
Espinosa K, Bosse Y, Stankova J, Rola-Pleszczynski M. CysLT1 receptor upregulation by TGF-beta and IL-13 is associated with bronchial smooth muscle cell proliferation in response to LTD4. J Allergy Clin Immunol 2003;111:1032-1040.
-
(2003)
J Allergy Clin Immunol
, vol.111
, pp. 1032-1040
-
-
Espinosa, K.1
Bosse, Y.2
Stankova, J.3
Rola-Pleszczynski, M.4
-
23
-
-
0036126690
-
Significant variability in response to inhaled corticosteroids for persistent asthma
-
Szefler SJ, et al. Significant variability in response to inhaled corticosteroids for persistent asthma. J Allergy Clin Immunol 2002;109:410-418.
-
(2002)
J Allergy Clin Immunol
, vol.109
, pp. 410-418
-
-
Szefler, S.J.1
-
24
-
-
33845929075
-
The Predicting Response to Inhaled Corticosteroid Efficacy (PRICE) trial
-
Martin RJ, et al. The Predicting Response to Inhaled Corticosteroid Efficacy (PRICE) trial. J Allergy Clin Immunol 2007;119:73-80.
-
(2007)
J Allergy Clin Immunol
, vol.119
, pp. 73-80
-
-
Martin, R.J.1
-
25
-
-
79959366545
-
-
National Heart Lung and Blood Institute. Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma. Washington, DC: US Department of Health and Human Services and the NIH
-
National Heart Lung and Blood Institute. Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma. Washington, DC: US Department of Health and Human Services and the NIH, 2007.
-
(2007)
-
-
-
26
-
-
61849152860
-
Eosinophils in asthma - closing the loop or opening the door?
-
Wenzel SE. Eosinophils in asthma - closing the loop or opening the door? N Engl J Med 2009;360:1026-1028.
-
(2009)
N Engl J Med
, vol.360
, pp. 1026-1028
-
-
Wenzel, S.E.1
-
27
-
-
34247485053
-
Noneosinophilic asthma: a distinct clinical and pathologic phenotype
-
quiz 1053-1054.
-
Haldar P, Pavord ID. Noneosinophilic asthma: a distinct clinical and pathologic phenotype. J Allergy Clin Immunol 2007;119:1043-1052, quiz 1053-1054.
-
(2007)
J Allergy Clin Immunol
, vol.119
, pp. 1043-1052
-
-
Haldar, P.1
Pavord, I.D.2
-
29
-
-
0036795111
-
Analysis of induced sputum in adults with asthma: identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids
-
Green RH, Brightling CE, Woltmann G, Parker D, Wardlaw AJ, Pavord ID. Analysis of induced sputum in adults with asthma: identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids. Thorax 2002;57:875-879.
-
(2002)
Thorax
, vol.57
, pp. 875-879
-
-
Green, R.H.1
Brightling, C.E.2
Woltmann, G.3
Parker, D.4
Wardlaw, A.J.5
Pavord, I.D.6
-
30
-
-
0032875377
-
Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics
-
Wenzel SE, et al. Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics. Am J Respir Crit Care Med 1999;160:1001-1008.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 1001-1008
-
-
Wenzel, S.E.1
-
31
-
-
77951665424
-
Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes
-
e1013.
-
Hastie AT, et al. Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes. J Allergy Clin Immunol 2010;125:1028-1036.e1013.
-
(2010)
J Allergy Clin Immunol
, vol.125
, pp. 1028-1036
-
-
Hastie, A.T.1
-
32
-
-
68849086058
-
Inflammatory subtypes in asthma are related to airway hyperresponsiveness to mannitol and exhaled NO
-
Porsbjerg C, Lund TK, Pedersen L, Backer V. Inflammatory subtypes in asthma are related to airway hyperresponsiveness to mannitol and exhaled NO. J Asthma 2009;46:606-612.
-
(2009)
J Asthma
, vol.46
, pp. 606-612
-
-
Porsbjerg, C.1
Lund, T.K.2
Pedersen, L.3
Backer, V.4
-
33
-
-
36749095585
-
Pathological features and inhaled corticosteroid response of eosinophilic and non-eosinophilic asthma
-
Berry M, et al. Pathological features and inhaled corticosteroid response of eosinophilic and non-eosinophilic asthma. Thorax 2007;62:1043-1049.
-
(2007)
Thorax
, vol.62
, pp. 1043-1049
-
-
Berry, M.1
-
34
-
-
31144451043
-
Biomarkers predicting response to corticosteroid therapy in asthma
-
Brightling CE, Green RH, Pavord ID. Biomarkers predicting response to corticosteroid therapy in asthma. Treat Respir Med 2005;4:309-316.
-
(2005)
Treat Respir Med
, vol.4
, pp. 309-316
-
-
Brightling, C.E.1
Green, R.H.2
Pavord, I.D.3
-
35
-
-
70349241725
-
Inflammatory phenotypes in adult asthma: clinical applications
-
Gibson PG. Inflammatory phenotypes in adult asthma: clinical applications. Clin Respir J 2009;3:198-206.
-
(2009)
Clin Respir J
, vol.3
, pp. 198-206
-
-
Gibson, P.G.1
-
36
-
-
0029278910
-
Prominent neutrophilic inflammation in sputum from subjects with asthma exacerbation
-
Fahy JV, Kim KW, Liu J, Boushey HA. Prominent neutrophilic inflammation in sputum from subjects with asthma exacerbation. J Allergy Clin Immunol 1995;95:843-852.
-
(1995)
J Allergy Clin Immunol
, vol.95
, pp. 843-852
-
-
Fahy, J.V.1
Kim, K.W.2
Liu, J.3
Boushey, H.A.4
-
37
-
-
0035177659
-
Relationship between airway inflammation, hyperresponsiveness, and obstruction in asthma
-
Woodruff PG, et al. Relationship between airway inflammation, hyperresponsiveness, and obstruction in asthma. J Allergy Clin Immunol 2001;108:753-758.
-
(2001)
J Allergy Clin Immunol
, vol.108
, pp. 753-758
-
-
Woodruff, P.G.1
-
38
-
-
0037090910
-
A role for neutrophils in asthma?
-
Woodruff PG, Fahy JV. A role for neutrophils in asthma? Am J Med 2002;112:498-500.
-
(2002)
Am J Med
, vol.112
, pp. 498-500
-
-
Woodruff, P.G.1
Fahy, J.V.2
-
39
-
-
48249085691
-
Cluster analysis and clinical asthma phenotypes
-
Haldar P, et al. Cluster analysis and clinical asthma phenotypes. Am J Respir Crit Care Med 2008;178:218-224.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 218-224
-
-
Haldar, P.1
-
40
-
-
0034526865
-
Proceedings of the ATS workshop on refractory asthma: current understanding, recommendations, and unanswered questions
-
American Thoracic Society.
-
American Thoracic Society. Proceedings of the ATS workshop on refractory asthma: current understanding, recommendations, and unanswered questions. Am J Respir Crit Care Med 2000;162:2341-2351.
-
(2000)
Am J Respir Crit Care Med
, vol.162
, pp. 2341-2351
-
-
-
42
-
-
51349125818
-
The association between obesity and asthma: interactions between systemic and airway inflammation
-
Sutherland TJ, et al. The association between obesity and asthma: interactions between systemic and airway inflammation. Am J Respir Crit Care Med 2008;178:469-475.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 469-475
-
-
Sutherland, T.J.1
-
43
-
-
76149146032
-
Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program
-
Moore WC, et al. Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am J Respir Crit Care Med 2010;181:315-323.
-
(2010)
Am J Respir Crit Care Med
, vol.181
, pp. 315-323
-
-
Moore, W.C.1
-
44
-
-
0031782594
-
Variation in the measurements of basement membrane thickness and inflammatory cell number in bronchial biopsies
-
Sullivan P, Stephens D, Ansari T, Costello J, Jeffery P. Variation in the measurements of basement membrane thickness and inflammatory cell number in bronchial biopsies. Eur Respir J 1998;12:811-815.
-
(1998)
Eur Respir J
, vol.12
, pp. 811-815
-
-
Sullivan, P.1
Stephens, D.2
Ansari, T.3
Costello, J.4
Jeffery, P.5
-
45
-
-
0025514183
-
Myofibroblasts and subepithelial fibrosis in bronchial asthma
-
Brewster CE, Howarth PH, Djukanovic R, Wilson J, Holgate ST, Roche WR. Myofibroblasts and subepithelial fibrosis in bronchial asthma. Am J Respir Cell Mol Biol 1990;3:507-511.
-
(1990)
Am J Respir Cell Mol Biol
, vol.3
, pp. 507-511
-
-
Brewster, C.E.1
Howarth, P.H.2
Djukanovic, R.3
Wilson, J.4
Holgate, S.T.5
Roche, W.R.6
-
47
-
-
0345734185
-
Applying stereology to measure thickness of the basement membrane zone in bronchial biopsy specimens
-
Ferrando RE, Nyengaard JR, Hays SR, Fahy JV, Woodruff PG. Applying stereology to measure thickness of the basement membrane zone in bronchial biopsy specimens. J Allergy Clin Immunol 2003;112:1243-1245.
-
(2003)
J Allergy Clin Immunol
, vol.112
, pp. 1243-1245
-
-
Ferrando, R.E.1
Nyengaard, J.R.2
Hays, S.R.3
Fahy, J.V.4
Woodruff, P.G.5
-
48
-
-
0037952701
-
Airway structural alterations selectively associated with severe asthma
-
Benayoun L, Druilhe A, Dombret MC, Aubier M, Pretolani M. Airway structural alterations selectively associated with severe asthma. Am J Respir Crit Care Med 2003;167:1360-1368.
-
(2003)
Am J Respir Crit Care Med
, vol.167
, pp. 1360-1368
-
-
Benayoun, L.1
Druilhe, A.2
Dombret, M.C.3
Aubier, M.4
Pretolani, M.5
-
49
-
-
11144358047
-
Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression
-
Woodruff PG, et al. Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression. Am J Respir Crit Care Med 2004;169:1001-1006.
-
(2004)
Am J Respir Crit Care Med
, vol.169
, pp. 1001-1006
-
-
Woodruff, P.G.1
-
50
-
-
78349235853
-
Pathophysiology of bronchial smooth muscle remodelling in asthma
-
Bara I, Ozier A, Tunon de Lara JM, Marthan R, Berger P. Pathophysiology of bronchial smooth muscle remodelling in asthma. Eur Respir J 2010;36:1174-1184.
-
(2010)
Eur Respir J
, vol.36
, pp. 1174-1184
-
-
Bara, I.1
Ozier, A.2
Tunon de Lara, J.M.3
Marthan, R.4
Berger, P.5
-
51
-
-
23244457836
-
Dissecting asthma using focused transgenic modeling and functional genomics
-
Kuperman DA, et al. Dissecting asthma using focused transgenic modeling and functional genomics. J Allergy Clin Immunol 2005;116:305-311.
-
(2005)
J Allergy Clin Immunol
, vol.116
, pp. 305-311
-
-
Kuperman, D.A.1
-
52
-
-
35649028488
-
Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids
-
Woodruff PG, et al. Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids. Proc Natl Acad Sci USA 2007;104:15858-15863.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 15858-15863
-
-
Woodruff, P.G.1
-
53
-
-
69249150516
-
T-helper type 2-driven inflammation defines major subphenotypes of asthma
-
Woodruff PG, et al. T-helper type 2-driven inflammation defines major subphenotypes of asthma. Am J Respir Crit Care Med 2009;180:388-395.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 388-395
-
-
Woodruff, P.G.1
-
54
-
-
77956289251
-
Roles of epithelial cell-derived periostin in TGF-beta activation, collagen production, and collagen gel elasticity in asthma
-
Sidhu SS, et al. Roles of epithelial cell-derived periostin in TGF-beta activation, collagen production, and collagen gel elasticity in asthma. Proc Natl Acad Sci USA 2010;107:14170-14175.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 14170-14175
-
-
Sidhu, S.S.1
-
55
-
-
33745394558
-
Periostin: a novel component of subepithelial fibrosis of bronchial asthma downstream of IL-4 and IL-13 signals
-
Takayama G, et al. Periostin: a novel component of subepithelial fibrosis of bronchial asthma downstream of IL-4 and IL-13 signals. J Allergy Clin Immunol 2006;118:98-104.
-
(2006)
J Allergy Clin Immunol
, vol.118
, pp. 98-104
-
-
Takayama, G.1
-
56
-
-
78650470207
-
SerpinB2 deficiency modulates Th1Th2 responses after schistosome infection
-
Schroder WA, et al. SerpinB2 deficiency modulates Th1Th2 responses after schistosome infection. Parasite Immunol 2010;32:764-768.
-
(2010)
Parasite Immunol
, vol.32
, pp. 764-768
-
-
Schroder, W.A.1
-
57
-
-
77951904395
-
A physiological function of inflammation-associated SerpinB2 is regulation of adaptive immunity
-
Schroder WA, et al. A physiological function of inflammation-associated SerpinB2 is regulation of adaptive immunity. J Immunol 2010;184:2663-2670.
-
(2010)
J Immunol
, vol.184
, pp. 2663-2670
-
-
Schroder, W.A.1
-
58
-
-
0034755576
-
Characterization of a calcium-activated chloride channel as a shared target of Th2 cytokine pathways and its potential involvement in asthma
-
Zhou Y, et al. Characterization of a calcium-activated chloride channel as a shared target of Th2 cytokine pathways and its potential involvement in asthma. Am J Respir Cell Mol Biol 2001;25:486-491.
-
(2001)
Am J Respir Cell Mol Biol
, vol.25
, pp. 486-491
-
-
Zhou, Y.1
-
59
-
-
0034618130
-
Mast cells can amplify airway reactivity and features of chronic inflammation in an asthma model in mice
-
Williams CM, Galli SJ. Mast cells can amplify airway reactivity and features of chronic inflammation in an asthma model in mice. J Exp Med 2000;192:455-462.
-
(2000)
J Exp Med
, vol.192
, pp. 455-462
-
-
Williams, C.M.1
Galli, S.J.2
-
60
-
-
33745225217
-
Mast cells can promote the development of multiple features of chronic asthma in mice
-
Yu M, Tsai M, Tam SY, Jones C, Zehnder J, Galli SJ. Mast cells can promote the development of multiple features of chronic asthma in mice. J Clin Invest 2006;116:1633-1641.
-
(2006)
J Clin Invest
, vol.116
, pp. 1633-1641
-
-
Yu, M.1
Tsai, M.2
Tam, S.Y.3
Jones, C.4
Zehnder, J.5
Galli, S.J.6
-
61
-
-
33745830136
-
A brief update on lung stereology
-
Ochs M. A brief update on lung stereology. J Microsc 2006;222:188-200.
-
(2006)
J Microsc
, vol.222
, pp. 188-200
-
-
Ochs, M.1
-
62
-
-
33846167119
-
How much is there really? Why stereology is essential in lung morphometry
-
Weibel ER, Hsia CC, Ochs M. How much is there really? Why stereology is essential in lung morphometry. J Appl Physiol 2007;102:459-467.
-
(2007)
J Appl Physiol
, vol.102
, pp. 459-467
-
-
Weibel, E.R.1
Hsia, C.C.2
Ochs, M.3
-
63
-
-
77951672627
-
Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma
-
e1048.
-
Dougherty RH, et al. Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma. J Allergy Clin Immunol 2010;125:1046-1053.e1048.
-
(2010)
J Allergy Clin Immunol
, vol.125
, pp. 1046-1053
-
-
Dougherty, R.H.1
-
64
-
-
79551511756
-
Mast cell phenotype, location and activation in severe asthma. Data from the Severe Asthma Research Program
-
Balzar S, et al. Mast cell phenotype, location and activation in severe asthma. Data from the Severe Asthma Research Program. Am J Respir Crit Care Med 2011;183:299-309.
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 299-309
-
-
Balzar, S.1
-
65
-
-
0029972142
-
Opposing effects of glucocorticoids on the rate of apoptosis in neutrophilic and eosinophilic granulocytes
-
Meagher LC, Cousin JM, Seckl JR, Haslett C. Opposing effects of glucocorticoids on the rate of apoptosis in neutrophilic and eosinophilic granulocytes. J Immunol 1996;156:4422-4428.
-
(1996)
J Immunol
, vol.156
, pp. 4422-4428
-
-
Meagher, L.C.1
Cousin, J.M.2
Seckl, J.R.3
Haslett, C.4
-
66
-
-
17844393640
-
Preclinical efficacy and safety of mepolizumab (SB-240563), a humanized monoclonal antibody to IL-5, in cynomolgus monkeys
-
Hart TK, et al. Preclinical efficacy and safety of mepolizumab (SB-240563), a humanized monoclonal antibody to IL-5, in cynomolgus monkeys. J Allergy Clin Immunol 2001;108:250-257.
-
(2001)
J Allergy Clin Immunol
, vol.108
, pp. 250-257
-
-
Hart, T.K.1
-
67
-
-
0033004943
-
The late asthmatic response is associated with baseline allergen-specific proliferative responsiveness of peripheral T lymphocytes in vitro and serum interleukin-5
-
van der Veen MJ, Van Neerven RJ, De Jong EC, Aalberse RC, Jansen HM, van der Zee JS. The late asthmatic response is associated with baseline allergen-specific proliferative responsiveness of peripheral T lymphocytes in vitro and serum interleukin-5. Clin Exp Allergy 1999;29:217-227.
-
(1999)
Clin Exp Allergy
, vol.29
, pp. 217-227
-
-
van der Veen, M.J.1
Van Neerven, R.J.2
De Jong, E.C.3
Aalberse, R.C.4
Jansen, H.M.5
van der Zee, J.S.6
-
68
-
-
6644229440
-
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response
-
Leckie MJ, et al. Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response. Lancet 2000;356:2144-2148.
-
(2000)
Lancet
, vol.356
, pp. 2144-2148
-
-
Leckie, M.J.1
-
69
-
-
36749065556
-
A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthma
-
Flood-Page P, et al. A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthma. Am J Respir Crit Care Med 2007;176:1062-1071.
-
(2007)
Am J Respir Crit Care Med
, vol.176
, pp. 1062-1071
-
-
Flood-Page, P.1
-
70
-
-
0037438409
-
Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway
-
Flood-Page PT, Menzies-Gow AN, Kay AB, Robinson DS. Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway. Am J Respir Crit Care Med 2003;167:199-204.
-
(2003)
Am J Respir Crit Care Med
, vol.167
, pp. 199-204
-
-
Flood-Page, P.T.1
Menzies-Gow, A.N.2
Kay, A.B.3
Robinson, D.S.4
-
71
-
-
61849086181
-
Mepolizumab and exacerbations of refractory eosinophilic asthma
-
Haldar P, et al. Mepolizumab and exacerbations of refractory eosinophilic asthma. N Engl J Med 2009;360:973-984.
-
(2009)
N Engl J Med
, vol.360
, pp. 973-984
-
-
Haldar, P.1
-
72
-
-
61849155730
-
Mepolizumab for prednisone-dependent asthma with sputum eosinophilia
-
Nair P, et al. Mepolizumab for prednisone-dependent asthma with sputum eosinophilia. N Engl J Med 2009;360:985-993.
-
(2009)
N Engl J Med
, vol.360
, pp. 985-993
-
-
Nair, P.1
-
73
-
-
0028787397
-
Glucocorticoids inhibit apoptosis of human neutrophils
-
Liles WC, Dale DC, Klebanoff SJ. Glucocorticoids inhibit apoptosis of human neutrophils. Blood 1995;86:3181-3188.
-
(1995)
Blood
, vol.86
, pp. 3181-3188
-
-
Liles, W.C.1
Dale, D.C.2
Klebanoff, S.J.3
-
74
-
-
35348909044
-
Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: results of two phase 2a studies
-
Wenzel S, Wilbraham D, Fuller R, Getz EB, Longphre M. Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: results of two phase 2a studies. Lancet 2007;370:1422-1431.
-
(2007)
Lancet
, vol.370
, pp. 1422-1431
-
-
Wenzel, S.1
Wilbraham, D.2
Fuller, R.3
Getz, E.B.4
Longphre, M.5
-
75
-
-
79954583416
-
The effects of IL-13 blockade on allergen-induced airway responses in mild atopic asthma
-
Gauvreau GM, et al. The effects of IL-13 blockade on allergen-induced airway responses in mild atopic asthma. Am J Respir Crit Care Med 2011;183:1007-1014.
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 1007-1014
-
-
Gauvreau, G.M.1
-
76
-
-
0036434681
-
Expression and activation of 15-lipoxygenase pathway in severe asthma: relationship to eosinophilic phenotype and collagen deposition
-
Chu HW, et al. Expression and activation of 15-lipoxygenase pathway in severe asthma: relationship to eosinophilic phenotype and collagen deposition. Clin Exp Allergy 2002;32:1558-1565.
-
(2002)
Clin Exp Allergy
, vol.32
, pp. 1558-1565
-
-
Chu, H.W.1
-
77
-
-
77954725559
-
DP(2) receptor antagonists in development
-
Norman P. DP(2) receptor antagonists in development. Expert Opin Investig Drugs 2010;19:947-961.
-
(2010)
Expert Opin Investig Drugs
, vol.19
, pp. 947-961
-
-
Norman, P.1
-
78
-
-
77953544246
-
Therapeutic efficacy of AM156, a novel prostanoid DP2 receptor antagonist, in murine models of allergic rhinitis and house dust mite-induced pulmonary inflammation
-
Stebbins KJ, et al. Therapeutic efficacy of AM156, a novel prostanoid DP2 receptor antagonist, in murine models of allergic rhinitis and house dust mite-induced pulmonary inflammation. Eur J Pharmacol 2010;638:142-149.
-
(2010)
Eur J Pharmacol
, vol.638
, pp. 142-149
-
-
Stebbins, K.J.1
-
79
-
-
73549084724
-
Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D2 synthase
-
Weber JE, et al. Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D2 synthase. Eur J Med Chem 2009;45:447-454.
-
(2009)
Eur J Med Chem
, vol.45
, pp. 447-454
-
-
Weber, J.E.1
-
80
-
-
59549107363
-
Correlation between the prostaglandin D(2)/E(2) ratio in nasal polyps and the recalcitrant pathophysiology of chronic rhinosinusitis associated with bronchial asthma
-
Yoshimura T, Yoshikawa M, Otori N, Haruna S, Moriyama H. Correlation between the prostaglandin D(2)/E(2) ratio in nasal polyps and the recalcitrant pathophysiology of chronic rhinosinusitis associated with bronchial asthma. Allergol Int 2008;57:429-436.
-
(2008)
Allergol Int
, vol.57
, pp. 429-436
-
-
Yoshimura, T.1
Yoshikawa, M.2
Otori, N.3
Haruna, S.4
Moriyama, H.5
-
81
-
-
0027231657
-
Cellular and biochemical analysis of induced sputum from asthmatic and from healthy subjects
-
Fahy JV, Liu J, Wong H, Boushey HA. Cellular and biochemical analysis of induced sputum from asthmatic and from healthy subjects. Am Rev Respir Dis 1993;147:1126-1131.
-
(1993)
Am Rev Respir Dis
, vol.147
, pp. 1126-1131
-
-
Fahy, J.V.1
Liu, J.2
Wong, H.3
Boushey, H.A.4
-
82
-
-
0029152965
-
Comparison of samples collected by sputum induction and bronchoscopy from asthmatic and healthy subjects
-
Fahy JV, Wong H, Liu J, Boushey HA. Comparison of samples collected by sputum induction and bronchoscopy from asthmatic and healthy subjects. Am J Respir Crit Care Med 1995;152:53-58.
-
(1995)
Am J Respir Crit Care Med
, vol.152
, pp. 53-58
-
-
Fahy, J.V.1
Wong, H.2
Liu, J.3
Boushey, H.A.4
-
83
-
-
0031011133
-
Cellular profiles in asthmatic airways: a comparison of induced sputum, bronchial washings, and bronchoalveolar lavage fluid
-
Keatings VM, Evans DJ, O'Connor BJ, Barnes PJ. Cellular profiles in asthmatic airways: a comparison of induced sputum, bronchial washings, and bronchoalveolar lavage fluid. Thorax 1997;52:372-374.
-
(1997)
Thorax
, vol.52
, pp. 372-374
-
-
Keatings, V.M.1
Evans, D.J.2
O'Connor, B.J.3
Barnes, P.J.4
-
84
-
-
0032990182
-
Prednisone-dependent asthma: inflammatory indices in induced sputum
-
Pizzichini MM, et al. Prednisone-dependent asthma: inflammatory indices in induced sputum. Eur Respir J 1999;13:15-21.
-
(1999)
Eur Respir J
, vol.13
, pp. 15-21
-
-
Pizzichini, M.M.1
-
86
-
-
0031917809
-
Dissociation between airway inflammation and airway hyperresponsiveness in allergic asthma
-
Crimi E, Spanevello A, Neri M, Ind PW, Rossi GA, Brusasco V. Dissociation between airway inflammation and airway hyperresponsiveness in allergic asthma. Am J Respir Crit Care Med 1998;157:4-9.
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 4-9
-
-
Crimi, E.1
Spanevello, A.2
Neri, M.3
Ind, P.W.4
Rossi, G.A.5
Brusasco, V.6
-
87
-
-
0033007431
-
Sputum analysis, bronchial hyperresponsiveness, and airway function in asthma: results of a factor analysis
-
Rosi E, Ronchi MC, Grazzini M, Duranti R, Scano G. Sputum analysis, bronchial hyperresponsiveness, and airway function in asthma: results of a factor analysis. J Allergy Clin Immunol 1999;103:232-237.
-
(1999)
J Allergy Clin Immunol
, vol.103
, pp. 232-237
-
-
Rosi, E.1
Ronchi, M.C.2
Grazzini, M.3
Duranti, R.4
Scano, G.5
-
88
-
-
0037202790
-
Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial
-
Green RH, et al. Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial. Lancet 2002;360:1715-1721.
-
(2002)
Lancet
, vol.360
, pp. 1715-1721
-
-
Green, R.H.1
-
89
-
-
33646787430
-
Strategy aimed at reduction of sputum eosinophils decreases exacerbation rate in patients with asthma
-
Chlumsky J, Striz I, Terl M, Vondracek J. Strategy aimed at reduction of sputum eosinophils decreases exacerbation rate in patients with asthma. J Int Med Res 2006;34:129-139.
-
(2006)
J Int Med Res
, vol.34
, pp. 129-139
-
-
Chlumsky, J.1
Striz, I.2
Terl, M.3
Vondracek, J.4
-
90
-
-
33344476409
-
Determining asthma treatment by monitoring sputum cell counts: effect on exacerbations
-
Jayaram L, et al. Determining asthma treatment by monitoring sputum cell counts: effect on exacerbations. Eur Respir J 2006;27:483-494.
-
(2006)
Eur Respir J
, vol.27
, pp. 483-494
-
-
Jayaram, L.1
-
91
-
-
0037339282
-
Reproducibility of exhaled nitric oxide measurements in healthy and asthmatic adults and children
-
Kharitonov SA, Gonio F, Kelly C, Meah S, Barnes PJ. Reproducibility of exhaled nitric oxide measurements in healthy and asthmatic adults and children. Eur Respir J 2003;21:433-438.
-
(2003)
Eur Respir J
, vol.21
, pp. 433-438
-
-
Kharitonov, S.A.1
Gonio, F.2
Kelly, C.3
Meah, S.4
Barnes, P.J.5
-
92
-
-
0028053173
-
Increased nitric oxide in exhaled air of asthmatic patients
-
Kharitonov SA, Yates D, Robbins RA, Logan-Sinclair R, Shinebourne EA, Barnes PJ. Increased nitric oxide in exhaled air of asthmatic patients. Lancet 1994;343:133-135.
-
(1994)
Lancet
, vol.343
, pp. 133-135
-
-
Kharitonov, S.A.1
Yates, D.2
Robbins, R.A.3
Logan-Sinclair, R.4
Shinebourne, E.A.5
Barnes, P.J.6
-
93
-
-
0027427353
-
Increased amount of nitric oxide in exhaled air of asthmatics
-
Alving K, Weitzberg E, Lundberg JM. Increased amount of nitric oxide in exhaled air of asthmatics. Eur Respir J 1993;6:1368-1370.
-
(1993)
Eur Respir J
, vol.6
, pp. 1368-1370
-
-
Alving, K.1
Weitzberg, E.2
Lundberg, J.M.3
-
94
-
-
0031900026
-
Correlation between exhaled nitric oxide, sputum eosinophils, and methacholine responsiveness in patients with mild asthma
-
Jatakanon A, Lim S, Kharitonov SA, Chung KF, Barnes PJ. Correlation between exhaled nitric oxide, sputum eosinophils, and methacholine responsiveness in patients with mild asthma. Thorax 1998;53:91-95.
-
(1998)
Thorax
, vol.53
, pp. 91-95
-
-
Jatakanon, A.1
Lim, S.2
Kharitonov, S.A.3
Chung, K.F.4
Barnes, P.J.5
-
95
-
-
0035888740
-
Relationship between exhaled nitric oxide and mucosal eosinophilic inflammation in children with difficult asthma, after treatment with oral prednisolone
-
Payne DN, Adcock IM, Wilson NM, Oates T, Scallan M, Bush A. Relationship between exhaled nitric oxide and mucosal eosinophilic inflammation in children with difficult asthma, after treatment with oral prednisolone. Am J Respir Crit Care Med 2001;164:1376-1381.
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 1376-1381
-
-
Payne, D.N.1
Adcock, I.M.2
Wilson, N.M.3
Oates, T.4
Scallan, M.5
Bush, A.6
-
96
-
-
33644773052
-
The use of exhaled nitric oxide concentration to identify eosinophilic airway inflammation: an observational study in adults with asthma
-
Berry MA, Shaw DE, Green RH, Brightling CE, Wardlaw AJ, Pavord ID. The use of exhaled nitric oxide concentration to identify eosinophilic airway inflammation: an observational study in adults with asthma. Clin Exp Allergy 2005;35:1175-1179.
-
(2005)
Clin Exp Allergy
, vol.35
, pp. 1175-1179
-
-
Berry, M.A.1
Shaw, D.E.2
Green, R.H.3
Brightling, C.E.4
Wardlaw, A.J.5
Pavord, I.D.6
-
97
-
-
34547557916
-
The use of exhaled nitric oxide to guide asthma management: a randomized controlled trial
-
Shaw DE, et al. The use of exhaled nitric oxide to guide asthma management: a randomized controlled trial. Am J Respir Crit Care Med 2007;176:231-237.
-
(2007)
Am J Respir Crit Care Med
, vol.176
, pp. 231-237
-
-
Shaw, D.E.1
-
98
-
-
19444385389
-
Use of exhaled nitric oxide measurements to guide treatment in chronic asthma
-
Smith AD, Cowan JO, Brassett KP, Herbison GP, Taylor DR. Use of exhaled nitric oxide measurements to guide treatment in chronic asthma. N Engl J Med 2005;352:2163-2173.
-
(2005)
N Engl J Med
, vol.352
, pp. 2163-2173
-
-
Smith, A.D.1
Cowan, J.O.2
Brassett, K.P.3
Herbison, G.P.4
Taylor, D.R.5
-
99
-
-
24644519265
-
Titrating steroids on exhaled nitric oxide in children with asthma: a randomized controlled trial
-
Pijnenburg MW, Bakker EM, Hop WC, De Jongste JC. Titrating steroids on exhaled nitric oxide in children with asthma: a randomized controlled trial. Am J Respir Crit Care Med 2005;172:831-836.
-
(2005)
Am J Respir Crit Care Med
, vol.172
, pp. 831-836
-
-
Pijnenburg, M.W.1
Bakker, E.M.2
Hop, W.C.3
De Jongste, J.C.4
-
100
-
-
77949500839
-
Determinants of exhaled nitric oxide in chronic rhinosinusitis
-
Guida G, et al. Determinants of exhaled nitric oxide in chronic rhinosinusitis. Chest 2010;137:658-664.
-
(2010)
Chest
, vol.137
, pp. 658-664
-
-
Guida, G.1
-
101
-
-
75649142498
-
External oligonucleotide standards enable cross laboratory comparison and exchange of real-time quantitative PCR data
-
Vermeulen J, et al. External oligonucleotide standards enable cross laboratory comparison and exchange of real-time quantitative PCR data. Nucleic Acids Res 2009;37:e138.
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Vermeulen, J.1
-
102
-
-
23944492134
-
Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database
-
Omenn GS, et al. Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database. Proteomics 2005;5:3226-3245.
-
(2005)
Proteomics
, vol.5
, pp. 3226-3245
-
-
Omenn, G.S.1
-
103
-
-
2542568705
-
The human plasma proteome: a nonredundant list developed by combination of four separate sources
-
Anderson NL, et al. The human plasma proteome: a nonredundant list developed by combination of four separate sources. Mol Cell Proteomics 2004;3:311-326.
-
(2004)
Mol Cell Proteomics
, vol.3
, pp. 311-326
-
-
Anderson, N.L.1
-
104
-
-
77951634577
-
Cell type-specific gene expression differences in complex tissues
-
Shen-Orr SS, et al. Cell type-specific gene expression differences in complex tissues. Nat Methods 2010;7:287-289.
-
(2010)
Nat Methods
, vol.7
, pp. 287-289
-
-
Shen-Orr, S.S.1
-
105
-
-
77952470787
-
Gene-expression profiling for rejection surveillance after cardiac transplantation
-
Pham MX, et al. Gene-expression profiling for rejection surveillance after cardiac transplantation. N Engl J Med 2010;362:1890-1900.
-
(2010)
N Engl J Med
, vol.362
, pp. 1890-1900
-
-
Pham, M.X.1
-
106
-
-
75749099357
-
Systemic sclerosis and lupus: points in an interferon-mediated continuum
-
Assassi S, et al. Systemic sclerosis and lupus: points in an interferon-mediated continuum. Arthritis Rheum 2010;62:589-598.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 589-598
-
-
Assassi, S.1
-
107
-
-
77955894773
-
An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis
-
Berry MP, et al. An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis. Nature 2010;466:973-977.
-
(2010)
Nature
, vol.466
, pp. 973-977
-
-
Berry, M.P.1
-
108
-
-
46749152178
-
A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus
-
Chaussabel D, et al. A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus. Immunity 2008;29:150-164.
-
(2008)
Immunity
, vol.29
, pp. 150-164
-
-
Chaussabel, D.1
-
110
-
-
55849148482
-
The cytokine network in asthma and chronic obstructive pulmonary disease
-
Barnes PJ. The cytokine network in asthma and chronic obstructive pulmonary disease. J Clin Invest 2008;118:3546-3556.
-
(2008)
J Clin Invest
, vol.118
, pp. 3546-3556
-
-
Barnes, P.J.1
-
111
-
-
19344362988
-
Oligonucleotide-microarray analysis of peripheral-blood lymphocytes in severe asthma
-
Hansel NN, et al. Oligonucleotide-microarray analysis of peripheral-blood lymphocytes in severe asthma. J Lab Clin Med 2005;145:263-274.
-
(2005)
J Lab Clin Med
, vol.145
, pp. 263-274
-
-
Hansel, N.N.1
-
112
-
-
26844520628
-
Profiling of genes expressed in peripheral blood mononuclear cells predicts glucocorticoid sensitivity in asthma patients
-
Hakonarson H, et al. Profiling of genes expressed in peripheral blood mononuclear cells predicts glucocorticoid sensitivity in asthma patients. Proc Natl Acad Sci USA 2005;102:14789-14794.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 14789-14794
-
-
Hakonarson, H.1
-
113
-
-
0033569406
-
Molecular classification of cancer: class discovery and class prediction by gene expression monitoring
-
Golub TR, et al. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 1999;286:531-537.
-
(1999)
Science
, vol.286
, pp. 531-537
-
-
Golub, T.R.1
-
114
-
-
33748693297
-
Validation and clinical utility of a 70-gene prognostic signature for women with node-negative breast cancer
-
Buyse M, et al. Validation and clinical utility of a 70-gene prognostic signature for women with node-negative breast cancer. J Natl Cancer Inst 2006;98:1183-1192.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 1183-1192
-
-
Buyse, M.1
-
115
-
-
33644610514
-
Noninvasive discrimination of rejection in cardiac allograft recipients using gene expression profiling
-
Deng MC, et al. Noninvasive discrimination of rejection in cardiac allograft recipients using gene expression profiling. Am J Transplant 2006;6:150-160.
-
(2006)
Am J Transplant
, vol.6
, pp. 150-160
-
-
Deng, M.C.1
-
116
-
-
38749130138
-
Interlaboratory performance of a microarray-based gene expression test to determine tissue of origin in poorly differentiated and undifferentiated cancers
-
Dumur CI, et al. Interlaboratory performance of a microarray-based gene expression test to determine tissue of origin in poorly differentiated and undifferentiated cancers. J Mol Diagn 2008;10:67-77.
-
(2008)
J Mol Diagn
, vol.10
, pp. 67-77
-
-
Dumur, C.I.1
-
117
-
-
0037059509
-
Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet
-
Finotto S, et al. Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet. Science 2002;295:336-338.
-
(2002)
Science
, vol.295
, pp. 336-338
-
-
Finotto, S.1
-
118
-
-
13444257864
-
TH1-mediated airway hyperresponsiveness independent of neutrophilic inflammation
-
Cui J, et al. TH1-mediated airway hyperresponsiveness independent of neutrophilic inflammation. J Allergy Clin Immunol 2005;115:309-315.
-
(2005)
J Allergy Clin Immunol
, vol.115
, pp. 309-315
-
-
Cui, J.1
-
119
-
-
35548946223
-
T helper 1 cells stimulated with ovalbumin and IL-18 induce airway hyperresponsiveness and lung fibrosis by IFN-gamma and IL-13 production
-
Hayashi N, Yoshimoto T, Izuhara K, Matsui K, Tanaka T, Nakanishi K. T helper 1 cells stimulated with ovalbumin and IL-18 induce airway hyperresponsiveness and lung fibrosis by IFN-gamma and IL-13 production. Proc Natl Acad Sci USA 2007;104:14765-14770.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 14765-14770
-
-
Hayashi, N.1
Yoshimoto, T.2
Izuhara, K.3
Matsui, K.4
Tanaka, T.5
Nakanishi, K.6
-
120
-
-
65249179610
-
Pathogenesis of steroid-resistant airway hyperresponsiveness: interaction between IFN-gamma and TLR4/MyD88 pathways
-
Yang M, Kumar RK, Foster PS. Pathogenesis of steroid-resistant airway hyperresponsiveness: interaction between IFN-gamma and TLR4/MyD88 pathways. J Immunol 2009;182:5107-5115.
-
(2009)
J Immunol
, vol.182
, pp. 5107-5115
-
-
Yang, M.1
Kumar, R.K.2
Foster, P.S.3
-
121
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
Park H, et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol 2005;6:1133-1141.
-
(2005)
Nat Immunol
, vol.6
, pp. 1133-1141
-
-
Park, H.1
-
122
-
-
27544490377
-
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
Harrington LE, et al. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 2005;6:1123-1132.
-
(2005)
Nat Immunol
, vol.6
, pp. 1123-1132
-
-
Harrington, L.E.1
-
123
-
-
69349093225
-
Interleukin-17 and type 17 helper T cells
-
Miossec P, Korn T, Kuchroo VK. Interleukin-17 and type 17 helper T cells. N Engl J Med 2009;361:888-898.
-
(2009)
N Engl J Med
, vol.361
, pp. 888-898
-
-
Miossec, P.1
Korn, T.2
Kuchroo, V.K.3
-
124
-
-
0034833339
-
IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines
-
Molet S, et al. IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines. J Allergy Clin Immunol 2001;108:430-438.
-
(2001)
J Allergy Clin Immunol
, vol.108
, pp. 430-438
-
-
Molet, S.1
-
125
-
-
33751180809
-
IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx?
-
Bullens DM, et al. IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx? Respir Res 2006;7:135.
-
(2006)
Respir Res
, vol.7
, pp. 135
-
-
Bullens, D.M.1
-
126
-
-
0037636682
-
Interleukin-17 in sputum correlates with airway hyperresponsiveness to methacholine
-
Barczyk A, Pierzchala W, Sozanska E. Interleukin-17 in sputum correlates with airway hyperresponsiveness to methacholine. Respir Med 2003;97:726-733.
-
(2003)
Respir Med
, vol.97
, pp. 726-733
-
-
Barczyk, A.1
Pierzchala, W.2
Sozanska, E.3
-
127
-
-
20944441664
-
Sputum interleukin-17 is increased and associated with airway neutrophilia in patients with severe asthma
-
Sun YC, Zhou QT, Yao WZ. Sputum interleukin-17 is increased and associated with airway neutrophilia in patients with severe asthma. Chin Med J (Engl) 2005;118:953-956.
-
(2005)
Chin Med J (Engl)
, vol.118
, pp. 953-956
-
-
Sun, Y.C.1
Zhou, Q.T.2
Yao, W.Z.3
-
128
-
-
67349203306
-
T(H)17-associated cytokines (IL-17A and IL-17F) in severe asthma
-
Al-Ramli W, et al. T(H)17-associated cytokines (IL-17A and IL-17F) in severe asthma. J Allergy Clin Immunol 2009;123:1185-1187.
-
(2009)
J Allergy Clin Immunol
, vol.123
, pp. 1185-1187
-
-
Al-Ramli, W.1
-
129
-
-
47249125726
-
Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes
-
Pene J, et al. Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes. J Immunol 2008;180:7423-7430.
-
(2008)
J Immunol
, vol.180
, pp. 7423-7430
-
-
Pene, J.1
-
130
-
-
78349269946
-
Expression of the T helper 17-associated cytokines IL-17A and IL-17F in asthma and COPD
-
Doe C, et al. Expression of the T helper 17-associated cytokines IL-17A and IL-17F in asthma and COPD. Chest 2010;138:1140-1147.
-
(2010)
Chest
, vol.138
, pp. 1140-1147
-
-
Doe, C.1
-
131
-
-
77953913216
-
Increased serum IL-17 is an independent risk factor for severe asthma
-
Agache I, Ciobanu C, Agache C, Anghel M. Increased serum IL-17 is an independent risk factor for severe asthma. Respir Med 2010;104:1131-1137.
-
(2010)
Respir Med
, vol.104
, pp. 1131-1137
-
-
Agache, I.1
Ciobanu, C.2
Agache, C.3
Anghel, M.4
-
133
-
-
0037592950
-
Stimulation of airway mucin gene expression by interleukin (IL)-17 through IL-6 paracrine/autocrine loop
-
Chen Y, Thai P, Zhao YH, Ho YS, DeSouza MM, Wu R. Stimulation of airway mucin gene expression by interleukin (IL)-17 through IL-6 paracrine/autocrine loop. J Biol Chem 2003;278:17036-17043.
-
(2003)
J Biol Chem
, vol.278
, pp. 17036-17043
-
-
Chen, Y.1
Thai, P.2
Zhao, Y.H.3
Ho, Y.S.4
DeSouza, M.M.5
Wu, R.6
-
134
-
-
77954239363
-
Regulation of airway MUC5AC expression by IL-1beta and IL-17A; the NF-kappaB paradigm
-
Fujisawa T, Velichko S, Thai P, Hung LY, Huang F, Wu R. Regulation of airway MUC5AC expression by IL-1beta and IL-17A; the NF-kappaB paradigm. J Immunol 2009;183:6236-6243.
-
(2009)
J Immunol
, vol.183
, pp. 6236-6243
-
-
Fujisawa, T.1
Velichko, S.2
Thai, P.3
Hung, L.Y.4
Huang, F.5
Wu, R.6
-
135
-
-
56149097181
-
TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice
-
McKinley L, et al. TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice. J Immunol 2008;181:4089-4097.
-
(2008)
J Immunol
, vol.181
, pp. 4089-4097
-
-
McKinley, L.1
-
136
-
-
43549110961
-
Regulation of inflammatory responses by IL-17F
-
Yang XO, et al. Regulation of inflammatory responses by IL-17F. J Exp Med 2008;205:1063-1075.
-
(2008)
J Exp Med
, vol.205
, pp. 1063-1075
-
-
Yang, X.O.1
-
137
-
-
78149326083
-
A novel subset of CD4(+) T(H)2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma
-
Wang YH, et al. A novel subset of CD4(+) T(H)2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma. J Exp Med 2010;207:2479-2491.
-
(2010)
J Exp Med
, vol.207
, pp. 2479-2491
-
-
Wang, Y.H.1
|