Mast cells can amplify airway reactivity and features of chronic inflammation in an asthma model in mice

Journal of Experimental Medicine

Volumn 192, Issue 3, 2000, Pages 455-462

  Williams, Cara M M ^a   Galli, Stephen J ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Eosinophil; Epithelium; Hyperresponsiveness; T lymphocyte; Tissue remodeling

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CELL INFILTRATION; CELL PROLIFERATION; CONGENIC STRAIN; DISEASE MODEL; EOSINOPHIL; HISTOPATHOLOGY; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ALLERGENS; ANIMALS; ASTHMA; DISEASE MODELS, ANIMAL; MAST CELLS; METHACHOLINE CHLORIDE; MICE; OVALBUMIN; RESPIRATORY HYPERSENSITIVITY; SODIUM CHLORIDE;

EID: 0034618130     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.192.3.455     Document Type: Article

References (32)

1. Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC
2. Therapeutic strategies for allergic diseases
3. The role of allergy, in the development of asthma
4. Induction and regulation of the IgE response
5. Signaling through the high-affinity IgE receptor FcεRI
6. Immunologic basis of antigen-induced airway hyperresponsiveness
7. Complexity and redundancy in the pathogenesis of asthma: Reassessing the roles of mast cells and T cells
8. Allergen-induced bronchial hyperreactivity and eosinophilic inflammation occur in the absence of IgE in a mouse model of asthma
9. Requirements for allergen-induced airway hyperreactivity in T and B cell deficient mice
10. Allergic eosinophil-rich inflammation develops in lungs and airways of B cell-deficient mice
11. Antigen-induced airway hyperresponsiveness, pulmonary eosinophilia, and chemokine expression in B cell-deficient mice
12. Anti-interleukin 5 but not anti-IgE prevents airway inflammation and airway hyperresponsiveness
13. Role of IgE in the development of allergic airway inflammation and airway hyperresponsiveness - A murine model
14. Mast cells modulate allergic pulmonary eosinophilia in mice
15. Development of eosinophilic airway inflammation and airway hyperresponsiveness in mast cell-deficient mice
16. Experimental pulmonary eosinophilia in mice by Ascaris suum extract
17. Attenuation of allergic airway inflammation in IL-4-deficient mice
18. T-cell-dependent accumulation of eosinophils in the lung and its inhibition by monoclonal anti-interleukin-5
19. Mast cell activation enhances airway responsiveness to methacholine in the mouse
20. Factors influencing the occurrence of a late reaction to allergen challenge in atopic asthmatics
21. Increases in airway eosinophils and interleukin-5 with minimal bronchoconstriction during repeated low-dose allergen challenge in atopic asthmatics
22. Decrease of mast cells in W/W mice and their increase by bone marrow transplantation
23. The kit ligand, stem cell factor
24. Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography
25. Selective staining of eosinophils and their immature precursors in tissue sections and autoradiographs with Congo red
26. Bromodeoxyuridine labeling studies on the proliferation of intestinal mucosal mast cells in normal and athymic rats
27. Epicutaneous sensitization with protein antigen induces localized allergic dermatitis and hyperresponsiveness to methacholine after single exposure to aerosolized antigen in mice
28. An essential role of mast cells in the development of airway hyperresponsiveness in a murine asthma model
29. Airway remodeling and repair
30. The bronchial epithelium as a key regulator of airway inflammation and remodelling in asthma
31. The inflammation-repair cycle in asthma: The pivotal role of the airway epithelium