Expression and activation of 15-lipoxygenase pathway in severe asthma: Relationship to eosinophilic phenotype and collagen deposition

Clinical and Experimental Allergy

Volumn 32, Issue 11, 2002, Pages 1558-1565

  Chu, H W ^a   Balzar, S ^a   Westcott, J Y ^a   Trudeau, J B ^a   Sun, Y ^a   Conrad, D J ^b   Wenzel, S E ^a  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

15(S) HETE; 15 lipoxygenase; Alveolar macrophages; Asthma; Eosinophils

Indexed keywords

5 HYDROXYICOSATETRAENOIC ACID; ARACHIDONATE 15 LIPOXYGENASE; COLLAGEN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; 15 HYDROXY 5,8,11,13 ICOSATETRAENOIC ACID; 15-HYDROXY-5,8,11,13-EICOSATETRAENOIC ACID; HYDROXYICOSATETRAENOIC ACID;

ADULT; AIRWAY; ALLERGIC ASTHMA; ARTICLE; BASEMENT MEMBRANE; BRONCHUS BIOPSY; BRONCHUS MUCOSA; CELL COUNT; CELL MEMBRANE; CONTROLLED STUDY; DISEASE SEVERITY; EOSINOPHIL; FEMALE; HUMAN; HUMAN TISSUE; INFLAMMATION; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; ASTHMA; BRONCHUS; CHEMISTRY; FIBROSIS; IMMUNOLOGY; METABOLISM; MIDDLE AGED; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ADULT; ARACHIDONATE 15-LIPOXYGENASE; ASTHMA; BRONCHI; BRONCHOALVEOLAR LAVAGE FLUID; COLLAGEN; EOSINOPHILS; FEMALE; FIBROSIS; HUMANS; HYDROXYEICOSATETRAENOIC ACIDS; MALE; MIDDLE AGED; SIGNAL TRANSDUCTION;

EID: 0036434681     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2222.2002.01477.x     Document Type: Article

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