메뉴 건너뛰기




Volumn 28, Issue , 2010, Pages 535-571

A genomic approach to human autoimmune diseases

Author keywords

Biomarkers; Blood; Juvenile arthritis; Lupus; Microarray

Indexed keywords

INTERFERON; INTERLEUKIN 6; TRANSCRIPTOME; BIOLOGICAL MARKER;

EID: 77952318708     PISSN: 07320582     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev-immunol-030409-101221     Document Type: Review
Times cited : (126)

References (198)
  • 1
    • 57449096122 scopus 로고    scopus 로고
    • A prescription for human immunology
    • Davis MM. 2008. A prescription for human immunology. Immunity 29:835-838
    • (2008) Immunity , vol.29 , pp. 835-838
    • Davis, M.M.1
  • 2
    • 33646879417 scopus 로고    scopus 로고
    • What do mouse models teach us about human SLE? Clin
    • Liu K, Mohan C. 2006. What do mouse models teach us about human SLE? Clin. Immunol. 119:123-130
    • (2006) Immunol. , vol.119 , pp. 123-130
    • Liu, K.1    Mohan, C.2
  • 3
    • 0034677123 scopus 로고    scopus 로고
    • Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice
    • Horai R, Saijo S, Tanioka H, Nakae S, Sudo K, et al. 2000. Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice. J. Exp. Med. 191:313-320
    • (2000) J. Exp. Med. , vol.191 , pp. 313-320
    • Horai, R.1    Saijo, S.2    Tanioka, H.3    Nakae, S.4    Sudo, K.5
  • 4
    • 67149130597 scopus 로고    scopus 로고
    • Anakinra for rheumatoid arthritis:asystematic review
    • MertensM, Singh JA. 2009. Anakinra for rheumatoid arthritis:asystematic review. J. Rheumatol. 36:1118-1125
    • (2009) J. Rheumatol. , vol.36 , pp. 1118-1125
    • Mertensm Singh, J.A.1
  • 5
    • 0035056003 scopus 로고    scopus 로고
    • Anti-TNFα therapy of rheumatoid arthritis: What have we learned?
    • Feldmann M, Maini RN. 2001. Anti-TNFα therapy of rheumatoid arthritis: What have we learned? Annu. Rev. Immunol. 19:163-196
    • (2001) Annu. Rev. Immunol. , vol.19 , pp. 163-196
    • Feldmann, M.1    Maini, R.N.2
  • 6
    • 0028806048 scopus 로고
    • Quantitative monitoring of gene expression patterns with a complementary DNA microarray
    • Schena M, Shalon D, Davis RW, Brown PO. 1995. Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science 270:467-470
    • (1995) Science , vol.270 , pp. 467-470
    • Schena, M.1    Shalon, D.2    Davis, R.W.3    Brown, P.O.4
  • 7
    • 0029812283 scopus 로고    scopus 로고
    • A DNA microarray system for analyzing complex DNA samples using two-color fluorescent probe hybridization
    • Shalon D, Smith SJ, Brown PO. 1996. A DNA microarray system for analyzing complex DNA samples using two-color fluorescent probe hybridization. Genome Res. 6:639-645
    • (1996) Genome Res. , vol.6 , pp. 639-645
    • Shalon, D.1    Smith, S.J.2    Brown, P.O.3
  • 8
    • 57749195712 scopus 로고    scopus 로고
    • RNA-Seq: A revolutionary tool for transcriptomics
    • Wang Z, Gerstein M, Snyder M. 2009. RNA-Seq: a revolutionary tool for transcriptomics. Nat. Rev. Genet. 10:57-63
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 57-63
    • Wang, Z.1    Gerstein, M.2    Snyder, M.3
  • 9
    • 0033569406 scopus 로고    scopus 로고
    • Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
    • Golub TR, Slonim DK, Tamayo P, Huard C, Gaasenbeek M, et al. 1999. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 286:531-537
    • (1999) Science , vol.286 , pp. 531-537
    • Golub, T.R.1    Slonim, D.K.2    Tamayo, P.3    Huard, C.4    Gaasenbeek, M.5
  • 10
    • 0034598746 scopus 로고    scopus 로고
    • Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
    • Alizadeh AA, Eisen MB, Davis RE, Ma C, Lossos IS, et al. 2000. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403:503-511
    • (2000) Nature , vol.403 , pp. 503-511
    • Alizadeh, A.A.1    Eisen, M.B.2    Davis, R.E.3    Ma, C.4    Lossos, I.S.5
  • 12
    • 60849097255 scopus 로고    scopus 로고
    • Gene-expression signatures in breast cancer
    • Sotiriou C, Pusztai L. 2009. Gene-expression signatures in breast cancer. N. Engl. J. Med. 360:790-800
    • (2009) N. Engl. J. Med. , vol.360 , pp. 790-800
    • Sotiriou, C.1    Pusztai, L.2
  • 13
    • 47249152715 scopus 로고    scopus 로고
    • How the study of children with rheumatic diseases identified interferon-α and interleukin-1 as novel therapeutic targets
    • Pascual V, Allantaz F, Patel P, Palucka AK, Chaussabel D, Banchereau J. 2008. How the study of children with rheumatic diseases identified interferon-α and interleukin-1 as novel therapeutic targets. Immunol. Rev. 223:39-59
    • (2008) Immunol. Rev. , vol.223 , pp. 39-59
    • Pascual, V.1    Allantaz, F.2    Patel, P.3    Palucka, A.K.4    Chaussabel, D.5    Banchereau, J.6
  • 14
    • 67650348463 scopus 로고    scopus 로고
    • Gene-expression profiling in rheumatic disease: Tools and therapeutic potential
    • Bauer JW, Bilgic H, Baechler EC. 2009. Gene-expression profiling in rheumatic disease: tools and therapeutic potential. Nat. Rev. Rheumatol. 5:257-265
    • (2009) Nat. Rev. Rheumatol. , vol.5 , pp. 257-265
    • Bauer, J.W.1    Bilgic, H.2    Baechler, E.C.3
  • 16
    • 69949148793 scopus 로고    scopus 로고
    • Gene expression signatures diagnose influenza and other symptomatic respiratory viral infections in humans
    • Zaas AK, Chen M, Varkey J, Veldman T, Hero AO, et al. 2009. Gene expression signatures diagnose influenza and other symptomatic respiratory viral infections in humans. Cell Host Microbe 6:207-217
    • (2009) Cell Host Microbe , vol.6 , pp. 207-217
    • Zaas, A.K.1    Chen, M.2    Varkey, J.3    Veldman, T.4    Hero, A.O.5
  • 17
    • 0037154274 scopus 로고    scopus 로고
    • Stereotyped and specific gene expression programs in human innate immune responses to bacteria
    • Boldrick JC, Alizadeh AA, Diehn M, Dudoit S, Liu CL, et al. 2002. Stereotyped and specific gene expression programs in human innate immune responses to bacteria. Proc. Natl. Acad. Sci. USA 99:972-977
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 972-977
    • Boldrick, J.C.1    Alizadeh, A.A.2    Diehn, M.3    Dudoit, S.4    Liu, C.L.5
  • 19
    • 18644385243 scopus 로고    scopus 로고
    • Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade
    • Pascual V, Allantaz F, Arce E, Punaro M, Banchereau J. 2005. Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade. J. Exp. Med. 201:1479-1486
    • (2005) J. Exp. Med. , vol.201 , pp. 1479-1486
    • Pascual, V.1    Allantaz, F.2    Arce, E.3    Punaro, M.4    Banchereau, J.5
  • 20
    • 40749100302 scopus 로고    scopus 로고
    • Identification of a molecular signature in human type 1 diabetes mellitus using serum and functional genomics
    • Wang X, Jia S, Geoffrey R, Alemzadeh R, Ghosh S, Hessner MJ. 2008. Identification of a molecular signature in human type 1 diabetes mellitus using serum and functional genomics. J. Immunol. 180:1929-1937
    • (2008) J. Immunol. , vol.180 , pp. 1929-1937
    • Wang, X.1    Jia, S.2    Geoffrey, R.3    Alemzadeh, R.4    Ghosh, S.5    Hessner, M.J.6
  • 21
    • 0037451167 scopus 로고    scopus 로고
    • Interferon and granulopoiesis signatures in systemic lupus erythematosus blood
    • Bennett L, Palucka AK, ArceE, Cantrell V, BorvakJ, et al. 2003. Interferon and granulopoiesis signatures in systemic lupus erythematosus blood. J. Exp. Med. 197:711-723
    • (2003) J. Exp. Med. , vol.197 , pp. 711-723
    • Bennett, L.1    Palucka, A.K.2    Arce, E.3    Cantrell, V.4    Borvak, J.5
  • 22
  • 23
    • 0242456113 scopus 로고    scopus 로고
    • Microarray analysis of gene expression in lupus
    • Crow MK, Wohlgemuth J. 2003. Microarray analysis of gene expression in lupus. Arthritis Res. Ther. 5:279-287
    • (2003) Arthritis Res. Ther. , vol.5 , pp. 279-287
    • Crow, M.K.1    Wohlgemuth, J.2
  • 24
    • 0141986842 scopus 로고    scopus 로고
    • Analysis of gene expression profiles in human systemic lupus erythematosus using oligonucleotide microarray
    • Han GM, Chen SL, Shen N, Ye S, Bao CD, Gu YY. 2003. Analysis of gene expression profiles in human systemic lupus erythematosus using oligonucleotide microarray. Genes Immun. 4:177-186
    • (2003) Genes Immun. , vol.4 , pp. 177-186
    • Han, G.M.1    Chen, S.L.2    Shen, N.3    Ye, S.4    Bao, C.D.5    Gu, Y.Y.6
  • 25
    • 34548436508 scopus 로고    scopus 로고
    • Blood leukocyte microarrays to diagnose systemic onset juvenile idiopathic arthritis and follow the response to IL-1 blockade
    • Allantaz F, Chaussabel D, Stichweh D, Bennett L, Allman W, et al. 2007. Blood leukocyte microarrays to diagnose systemic onset juvenile idiopathic arthritis and follow the response to IL-1 blockade. J. Exp. Med. 204:2131-2144
    • (2007) J. Exp. Med. , vol.204 , pp. 2131-2144
    • Allantaz, F.1    Chaussabel, D.2    Stichweh, D.3    Bennett, L.4    Allman, W.5
  • 26
    • 34447523762 scopus 로고    scopus 로고
    • Specific gene expression profiles in systemic juvenile idiopathic arthritis
    • Ogilvie EM, Khan A, Hubank M, Kellam P, Woo P. 2007. Specific gene expression profiles in systemic juvenile idiopathic arthritis. Arthritis Rheum. 56:1954-1965
    • (2007) Arthritis Rheum. , vol.56 , pp. 1954-1965
    • Ogilvie, E.M.1    Khan, A.2    Hubank, M.3    Kellam, P.4    Woo, P.5
  • 27
    • 36049020585 scopus 로고    scopus 로고
    • Gene expression profiling of peripheral blood from patients with untreated new-onset systemic juvenile idiopathic arthritis reveals molecular heterogeneity that may predict macrophage activation syndrome
    • Fall N, Barnes M, Thornton S, Luyrink L, Olson J, et al. 2007. Gene expression profiling of peripheral blood from patients with untreated new-onset systemic juvenile idiopathic arthritis reveals molecular heterogeneity that may predict macrophage activation syndrome. Arthritis Rheum. 56:3793-3804
    • (2007) Arthritis Rheum. , vol.56 , pp. 3793-3804
    • Fall, N.1    Barnes, M.2    Thornton, S.3    Luyrink, L.4    Olson, J.5
  • 28
    • 67650066800 scopus 로고    scopus 로고
    • Subtype-specific peripheral blood gene expression profiles in recent-onset juvenile idiopathic arthritis
    • Barnes MG, Grom AA, Thompson SD, Griffin TA, Pavlidis P, et al. 2009. Subtype-specific peripheral blood gene expression profiles in recent-onset juvenile idiopathic arthritis. Arthritis Rheum. 60:2102-2112
    • (2009) Arthritis Rheum. , vol.60 , pp. 2102-2112
    • Barnes, M.G.1    Grom, A.A.2    Thompson, S.D.3    Griffin, T.A.4    Pavlidis, P.5
  • 29
    • 34648835408 scopus 로고    scopus 로고
    • Impaired expressionofperipheral blood apoptotic-related gene transcripts in acute multiple sclerosis relapse
    • AchironA, FeldmanA, MandelM, GurevichM. 2007. Impaired expressionofperipheral blood apoptotic-related gene transcripts in acute multiple sclerosis relapse. Ann. N. Y. Acad. Sci. 1107:155-167
    • (2007) Ann. N. Y. Acad. Sci. , vol.1107 , pp. 155-167
    • Feldmana, A.1    Mandelm, GurevichM.2
  • 30
    • 34249891600 scopus 로고    scopus 로고
    • Gene expression changes in peripheral blood mononuclear cells from multiple sclerosis patients undergoing beta-interferon therapy
    • Singh MK, Scott TF, LaFramboise WA, Hu FZ, Post JC, Ehrlich GD. 2007. Gene expression changes in peripheral blood mononuclear cells from multiple sclerosis patients undergoing beta-interferon therapy. J. Neurol. Sci. 258:52-59
    • (2007) J. Neurol. Sci. , vol.258 , pp. 52-59
    • Singh, M.K.1    Scott, T.F.2    Laframboise, W.A.3    Hu, F.Z.4    Post, J.C.5    Ehrlich, G.D.6
  • 31
    • 34249001625 scopus 로고    scopus 로고
    • Molecular profile of peripheral blood mononuclear cells from patients with rheumatoid arthritis
    • Edwards CJ, Feldman JL, Beech J, Shields KM, Stover JA, et al. 2007. Molecular profile of peripheral blood mononuclear cells from patients with rheumatoid arthritis. Mol. Med. 13:40-58
    • (2007) Mol. Med. , vol.13 , pp. 40-58
    • Edwards, C.J.1    Feldman, J.L.2    Beech, J.3    Shields, K.M.4    Stover, J.A.5
  • 32
    • 34249712937 scopus 로고    scopus 로고
    • Rheumatoid arthritis subtypes identified by genomic profiling of peripheral blood cells: Assignment of a type i interferon signature in a subpopulation of patients
    • Van Der Pouw Kraan TC, Wijbrandts CA, van Baarsen LG, Voskuyl AE, Rustenburg F, et al. 2007. Rheumatoid arthritis subtypes identified by genomic profiling of peripheral blood cells: assignment of a type I interferon signature in a subpopulation of patients. Ann. Rheum. Dis. 66:1008-1014
    • (2007) Ann. Rheum. Dis. , vol.66 , pp. 1008-1014
    • Van Der Pouw Kraan, T.C.1    Wijbrandts, C.A.2    Van Baarsen, L.G.3    Voskuyl, A.E.4    Rustenburg, F.5
  • 37
    • 34547502060 scopus 로고    scopus 로고
    • Gene expression profiles in peripheral blood mononuclear cells reflect the pathophysiology of type 2 diabetes
    • Takamura T, Honda M, Sakai Y, Ando H, Shimizu A, et al. 2007. Gene expression profiles in peripheral blood mononuclear cells reflect the pathophysiology of type 2 diabetes. Biochem. Biophys. Res. Commun. 361:379-384
    • (2007) Biochem. Biophys. Res. Commun. , vol.361 , pp. 379-384
    • Takamura, T.1    Honda, M.2    Sakai, Y.3    Ando, H.4    Shimizu, A.5
  • 38
    • 32944470084 scopus 로고    scopus 로고
    • Molecular classification of Crohn's disease and ulcerative colitis patients using transcriptional profiles in peripheral blood mononuclear cells
    • Burczynski ME, Peterson RL, Twine NC, Zuberek KA, Brodeur BJ, et al. 2006. Molecular classification of Crohn's disease and ulcerative colitis patients using transcriptional profiles in peripheral blood mononuclear cells. J. Mol. Diagn. 8:51-61
    • (2006) J. Mol. Diagn. , vol.8 , pp. 51-61
    • Burczynski, M.E.1    Peterson, R.L.2    Twine, N.C.3    Zuberek, K.A.4    Brodeur, B.J.5
  • 40
    • 33646507867 scopus 로고    scopus 로고
    • Microarray analyses of peripheral blood cells identifies unique gene expression signature in psoriatic arthritis
    • Batliwalla FM, Li W, Ritchlin CT, Xiao X, Brenner M, et al. 2005. Microarray analyses of peripheral blood cells identifies unique gene expression signature in psoriatic arthritis. Mol. Med. 11:21-29
    • (2005) Mol. Med. , vol.11 , pp. 21-29
    • Batliwalla, F.M.1    Li, W.2    Ritchlin, C.T.3    Xiao, X.4    Brenner, M.5
  • 42
    • 34248998426 scopus 로고    scopus 로고
    • An interferon signature in the peripheral blood of dermatomyositis patients is associated with disease activity
    • Baechler EC, Bauer JW, Slattery CA, Ortmann WA, Espe KJ, et al. 2007. An interferon signature in the peripheral blood of dermatomyositis patients is associated with disease activity. Mol. Med. 13:59-68
    • (2007) Mol. Med. , vol.13 , pp. 59-68
    • Baechler, E.C.1    Bauer, J.W.2    Slattery, C.A.3    Ortmann, W.A.4    Espe, K.J.5
  • 43
    • 33745625865 scopus 로고    scopus 로고
    • Signatures of differentially regulated interferon gene expression and vasculotrophisminthe peripheral blood cellsof systemic sclerosis patients
    • Tan FK, Zhou X, Mayes MD, Gourh P, Guo X, et al. 2006. Signatures of differentially regulated interferon gene expression and vasculotrophisminthe peripheral blood cellsof systemic sclerosis patients. Rheumatology (Oxford) 45:694-702
    • (2006) Rheumatology (Oxford) , vol.45 , pp. 694-702
    • Tan, F.K.1    Zhou, X.2    Mayes, M.D.3    Gourh, P.4    Guo, X.5
  • 44
    • 33947154329 scopus 로고    scopus 로고
    • A macrophage marker, Siglec-1, is increased on circulating monocytes in patients with systemic sclerosis and induced by type i interferons and Toll-like receptor agonists
    • York MR, Nagai T, Mangini AJ, Lemaire R, van Seventer JM, Lafyatis R. 2007. A macrophage marker, Siglec-1, is increased on circulating monocytes in patients with systemic sclerosis and induced by type I interferons and Toll-like receptor agonists. Arthritis Rheum. 56:1010-1020
    • (2007) Arthritis Rheum. , vol.56 , pp. 1010-1020
    • York, M.R.1    Nagai, T.2    Mangini, A.J.3    Lemaire, R.4    Van Seventer, J.M.5    Lafyatis, R.6
  • 45
    • 34648823219 scopus 로고    scopus 로고
    • Leukocyte gene expression signatures in antineutrophil cytoplasmic autoantibody and lupus glomerulonephritis
    • Alcorta DA, Barnes DA, Dooley MA, Sullivan P, Jonas B, et al. 2007. Leukocyte gene expression signatures in antineutrophil cytoplasmic autoantibody and lupus glomerulonephritis. Kidney Int. 72:853-864
    • (2007) Kidney Int. , vol.72 , pp. 853-864
    • Alcorta, D.A.1    Barnes, D.A.2    Dooley, M.A.3    Sullivan, P.4    Jonas, B.5
  • 46
    • 32644434384 scopus 로고    scopus 로고
    • Gene-expression patterns predict phenotypes of immune-mediated thrombosis
    • Potti A, Bild A, Dressman HK, Lewis DA, Nevins JR, Ortel TL. 2006. Gene-expression patterns predict phenotypes of immune-mediated thrombosis. Blood 107:1391-1396
    • (2006) Blood , vol.107 , pp. 1391-1396
    • Potti, A.1    Bild, A.2    Dressman, H.K.3    Lewis, D.A.4    Nevins, J.R.5    Ortel, T.L.6
  • 47
    • 33645790477 scopus 로고    scopus 로고
    • Gene expression profiles in hepatitis C virus (HCV) and HIV coinfection: Class prediction analyses before treatment predict the outcome of anti-HCV therapy among HIV-coinfected persons
    • Lempicki RA, Polis MA, Yang J, McLaughlin M, Koratich C, et al. 2006. Gene expression profiles in hepatitis C virus (HCV) and HIV coinfection: class prediction analyses before treatment predict the outcome of anti-HCV therapy among HIV-coinfected persons. J. Infect. Dis. 193:1172-1177
    • (2006) J. Infect. Dis. , vol.193 , pp. 1172-1177
    • Lempicki, R.A.1    Polis, M.A.2    Yang, J.3    McLaughlin, M.4    Koratich, C.5
  • 48
    • 27844515156 scopus 로고    scopus 로고
    • Surveillance of transcriptomes in basic military trainees with normal, febrile respiratory illness, and convalescent phenotypes
    • Thach DC, Agan BK, Olsen C, Diao J, Lin B, et al. 2005. Surveillance of transcriptomes in basic military trainees with normal, febrile respiratory illness, and convalescent phenotypes. Genes Immun. 6:588-595
    • (2005) Genes Immun. , vol.6 , pp. 588-595
    • Thach, D.C.1    Agan, B.K.2    Olsen, C.3    Diao, J.4    Lin, B.5
  • 50
    • 33847408050 scopus 로고    scopus 로고
    • Gene expression patterns in blood leukocytes discriminate patients with acute infections
    • Ramilo O, Allman W, Chung W, Mejias A, Ardura M, et al. 2007. Gene expression patterns in blood leukocytes discriminate patients with acute infections. Blood 109:2066-2077
    • (2007) Blood , vol.109 , pp. 2066-2077
    • Ramilo, O.1    Allman, W.2    Chung, W.3    Mejias, A.4    Ardura, M.5
  • 51
    • 34047235096 scopus 로고    scopus 로고
    • Patterns of host genome-wide gene transcript abundance in the peripheral blood of patients with acute dengue hemorrhagic fever
    • Simmons CP, Popper S, Dolocek C, Chau TN, Griffiths M, et al. 2007. Patterns of host genome-wide gene transcript abundance in the peripheral blood of patients with acute dengue hemorrhagic fever. J. Infect. Dis. 195:1097-1107
    • (2007) J. Infect. Dis. , vol.195 , pp. 1097-1107
    • Simmons, C.P.1    Popper, S.2    Dolocek, C.3    Chau, T.N.4    Griffiths, M.5
  • 52
    • 65549116870 scopus 로고    scopus 로고
    • Enhanced monocyte response and decreased central memory T cells in children with invasive Staphylococcus aureus infections
    • Ardura MI, Banchereau R, Mejias A, Di Pucchio T, Glaser C, et al. 2009. Enhanced monocyte response and decreased central memory T cells in children with invasive Staphylococcus aureus infections. PLoS One 4:e5446
    • (2009) PLoS One , vol.4
    • Ardura, M.I.1    Banchereau, R.2    Mejias, A.3    Di Pucchio, T.4    Glaser, C.5
  • 53
    • 34249948116 scopus 로고    scopus 로고
    • Candidate biomarkers for discrimination between infection and disease caused by Mycobacterium tuberculosis
    • Jacobsen M, Repsilber D, Gutschmidt A, Neher A, Feldmann K, et al. 2007. Candidate biomarkers for discrimination between infection and disease caused by Mycobacterium tuberculosis. J. Mol. Med. 85:613-621
    • (2007) J. Mol. Med. , vol.85 , pp. 613-621
    • Jacobsen, M.1    Repsilber, D.2    Gutschmidt, A.3    Neher, A.4    Feldmann, K.5
  • 54
    • 33749233853 scopus 로고    scopus 로고
    • Common and divergent immune response signaling pathways discovered in peripheral blood mononuclear cell gene expression patterns in presymptomatic and clinically apparent malaria
    • Ockenhouse CF, Hu WC, Kester KE, Cummings JF, Stewart A, et al. 2006. Common and divergent immune response signaling pathways discovered in peripheral blood mononuclear cell gene expression patterns in presymptomatic and clinically apparent malaria. Infect. Immun. 74:5561-5573
    • (2006) Infect. Immun. , vol.74 , pp. 5561-5573
    • Ockenhouse, C.F.1    Hu, W.C.2    Kester, K.E.3    Cummings, J.F.4    Stewart, A.5
  • 56
    • 0036843890 scopus 로고    scopus 로고
    • Identification of novel genes associated with immunosuppression in renal transplant patients
    • Zhang HQ, Lu H, Enosawa S, Takahara S, Sakamoto S, Suzuki S. 2002. Identification of novel genes associated with immunosuppression in renal transplant patients. Transplant. Proc. 34:2733-2735
    • (2002) Transplant. Proc. , vol.34 , pp. 2733-2735
    • Zhang, H.Q.1    Lu, H.2    Enosawa, S.3    Takahara, S.4    Sakamoto, S.5    Suzuki, S.6
  • 58
    • 33644610514 scopus 로고    scopus 로고
    • Noninvasive discrimination of rejection in cardiac allograft recipients using gene expression profiling
    • Deng MC, Eisen HJ, Mehra MR, Billingham M, Marboe CC, et al. 2006. Noninvasive discrimination of rejection in cardiac allograft recipients using gene expression profiling. Am. J. Transplant. 6:150-160
    • (2006) Am. J. Transplant. , vol.6 , pp. 150-160
    • Deng, M.C.1    Eisen, H.J.2    Mehra, M.R.3    Billingham, M.4    Marboe, C.C.5
  • 59
    • 33846706250 scopus 로고    scopus 로고
    • Prediction of graft-versus-host disease in humans by donor gene-expression profiling
    • Baron C, Somogyi R, Greller LD, Rineau V, Wilkinson P, et al. 2007. Prediction of graft-versus-host disease in humans by donor gene-expression profiling. PLoS Med. 4:e23
    • (2007) PLoS Med. , vol.4
    • Baron, C.1    Somogyi, R.2    Greller, L.D.3    Rineau, V.4    Wilkinson, P.5
  • 60
    • 33745904218 scopus 로고    scopus 로고
    • Gene expression in blood changes rapidly in neutrophils and monocytes after ischemic stroke in humans: A microarray study
    • Tang Y, Xu H, Du X, Lit L, Walker W, et al. 2006. Gene expression in blood changes rapidly in neutrophils and monocytes after ischemic stroke in humans: a microarray study. J. Cereb. Blood Flow Metab. 26:1089-1102
    • (2006) J. Cereb. Blood Flow Metab. , vol.26 , pp. 1089-1102
    • Tang, Y.1    Xu, H.2    Du, X.3    Lit, L.4    Walker, W.5
  • 61
    • 33750454758 scopus 로고    scopus 로고
    • Microarray-based identification and RT-PCR test screening for epithelial-specific mRNAs in peripheral blood of patients with colon cancer
    • Solmi R, Ugolini G, Rosati G, Zanotti S, Lauriola M, et al. 2006. Microarray-based identification and RT-PCR test screening for epithelial-specific mRNAs in peripheral blood of patients with colon cancer. BMC Cancer 6:250
    • (2006) BMC Cancer , vol.6 , pp. 250
    • Solmi, R.1    Ugolini, G.2    Rosati, G.3    Zanotti, S.4    Lauriola, M.5
  • 63
    • 0028962115 scopus 로고
    • Role of interleukin 10 in the B lymphocyte hyperactivity and autoantibody production of human systemic lupus erythematosus
    • Llorente L, Zou W, Levy Y, Richaud-Patin Y, Wijdenes J, et al. 1995. Role of interleukin 10 in the B lymphocyte hyperactivity and autoantibody production of human systemic lupus erythematosus. J. Exp. Med. 181:839-844
    • (1995) J. Exp. Med. , vol.181 , pp. 839-844
    • Llorente, L.1    Zou, W.2    Levy, Y.3    Richaud-Patin, Y.4    Wijdenes, J.5
  • 64
    • 0033883903 scopus 로고    scopus 로고
    • Clinical and biologic effects of anti-interleukin-10 monoclonal antibody administration in systemic lupus erythematosus
    • Llorente L, Richaud-Patin Y, Garcia-Padilla C, Claret E, Jakez-Ocampo J, et al. 2000. Clinical and biologic effects of anti-interleukin-10 monoclonal antibody administration in systemic lupus erythematosus. Arthritis Rheum. 43:1790-1800
    • (2000) Arthritis Rheum. , vol.43 , pp. 1790-1800
    • Llorente, L.1    Richaud-Patin, Y.2    Garcia-Padilla, C.3    Claret, E.4    Jakez-Ocampo, J.5
  • 65
    • 0026788334 scopus 로고
    • Up-regulated MHC-class II expression and γ-IFN and soluble IL-2R in lupus nephritis
    • Yokoyama H, Takabatake T, Takaeda M, Wada T, Naito T, et al. 1992. Up-regulated MHC-class II expression and γ-IFN and soluble IL-2R in lupus nephritis. Kidney Int. 42:755-763
    • (1992) Kidney Int. , vol.42 , pp. 755-763
    • Yokoyama, H.1    Takabatake, T.2    Takaeda, M.3    Wada, T.4    Naito, T.5
  • 66
    • 0031155269 scopus 로고    scopus 로고
    • IFN-γis essential for the development of autoimmune glomeru-lonephritis in MRL/Ipr mice
    • Haas C, Ryffel B, Le Hir M. 1997. IFN-γ is essential for the development of autoimmune glomeru-lonephritis in MRL/Ipr mice. J. Immunol. 158:5484-5491
    • (1997) J. Immunol. , vol.158 , pp. 5484-5491
    • Haas, C.1    Ryffel, B.2    Le Hir, M.3
  • 67
    • 0031977667 scopus 로고    scopus 로고
    • Decreased production of interleukin-12 and other Th1-type cytokines in patients with recent-onset systemic lupus erythematosus
    • Horwitz DA, Gray JD, Behrendsen SC, Kubin M, Rengaraju M, et al. 1998. Decreased production of interleukin-12 and other Th1-type cytokines in patients with recent-onset systemic lupus erythematosus. Arthritis Rheum. 41:838-844
    • (1998) Arthritis Rheum. , vol.41 , pp. 838-844
    • Horwitz, D.A.1    Gray, J.D.2    Behrendsen, S.C.3    Kubin, M.4    Rengaraju, M.5
  • 68
    • 0014552008 scopus 로고
    • The pathogenesis of autoimmunity in New Zealand mice, I. Induction of antinucleic acid antibodies by polyinosinic-polycytidylic acid
    • Steinberg AD, Baron S, Talal N. 1969. The pathogenesis of autoimmunity in New Zealand mice, I. Induction of antinucleic acid antibodies by polyinosinic-polycytidylic acid. Proc. Natl. Acad. Sci. USA 63:1102-1107
    • (1969) Proc. Natl. Acad. Sci. USA , vol.63 , pp. 1102-1107
    • Steinberg, A.D.1    Baron, S.2    Talal, N.3
  • 70
    • 0037379578 scopus 로고    scopus 로고
    • Neutralizing interferon alpha as a therapeutic approach to autoimmune diseases
    • Stewart TA. 2003. Neutralizing interferon alpha as a therapeutic approach to autoimmune diseases. Cytokine Growth Factor Rev. 14:139-154
    • (2003) Cytokine Growth Factor Rev. , vol.14 , pp. 139-154
    • Stewart, T.A.1
  • 71
    • 0032191321 scopus 로고    scopus 로고
    • Patients with systemic lupus erythematosus have reduced numbers of circulating natural interferon-α-producing cells
    • Cederblad B, Blomberg S, Vallin H, Perers A, Alm GV, Ronnblom L. 1998. Patients with systemic lupus erythematosus have reduced numbers of circulating natural interferon-α-producing cells. J. Autoimmun. 11:465-470
    • (1998) J. Autoimmun. , vol.11 , pp. 465-470
    • Cederblad, B.1    Blomberg, S.2    Vallin, H.3    Perers, A.4    Alm, G.V.5    Ronnblom, L.6
  • 72
    • 0034913451 scopus 로고    scopus 로고
    • Presenceofcutaneous interferon-a producing cells in patients with systemic lupus erythematosus
    • Blomberg S, Eloranta ML, Cederblad B, Nordlin K, Alm GV, Ronnblom L. 2001. Presenceofcutaneous interferon-a producing cells in patients with systemic lupus erythematosus. Lupus 10:484-490
    • (2001) Lupus , vol.10 , pp. 484-490
    • Blomberg, S.1    Eloranta, M.L.2    Cederblad, B.3    Nordlin, K.4    Alm, G.V.5    Ronnblom, L.6
  • 73
    • 0035403969 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells (natural interferon-α/β-producing cells) accumulate in cutaneous lupus erythematosus lesions
    • Farkas L, Beiske K, Lund-Johansen F, Brandtzaeg P, Jahnsen FL. 2001. Plasmacytoid dendritic cells (natural interferon-α/β-producing cells) accumulate in cutaneous lupus erythematosus lesions. Am. J. Pathol. 159:237-243
    • (2001) Am. J. Pathol. , vol.159 , pp. 237-243
    • Farkas, L.1    Beiske, K.2    Lund-Johansen, F.3    Brandtzaeg, P.4    Jahnsen, F.L.5
  • 74
    • 0032950459 scopus 로고    scopus 로고
    • Patients with systemic lupus erythe-matosus (SLE) have a circulating inducer of interferon-alpha (IFN-α) production acting on leucocytes resembling immature dendritic cells
    • Vallin H, Blomberg S, Alm GV, Cederblad B, Ronnblom L. 1999. Patients with systemic lupus erythe-matosus (SLE) have a circulating inducer of interferon-alpha (IFN-α) production acting on leucocytes resembling immature dendritic cells. Clin. Exp. Immunol. 115:196-202
    • (1999) Clin. Exp. Immunol. , vol.115 , pp. 196-202
    • Vallin, H.1    Blomberg, S.2    Alm, G.V.3    Cederblad, B.4    Ronnblom, L.5
  • 75
    • 0035421308 scopus 로고    scopus 로고
    • Activation of natural interferon-α producing cells by apoptotic U937 cells combined with lupus IgG and its regulation by cytokines
    • Bave U, Vallin H, Alm GV, Ronnblom L. 2001. Activation of natural interferon-α producing cells by apoptotic U937 cells combined with lupus IgG and its regulation by cytokines. J. Autoimmun. 17:71-80
    • (2001) J. Autoimmun. , vol.17 , pp. 71-80
    • Bave, U.1    Vallin, H.2    Alm, G.V.3    Ronnblom, L.4
  • 76
    • 0035900481 scopus 로고    scopus 로고
    • Induction of dendritic cell differentiation by IFN-α in systemic lupus erythematosus
    • Blanco P, Palucka AK, Gill M, Pascual V, Banchereau J. 2001. Induction of dendritic cell differentiation by IFN-α in systemic lupus erythematosus. Science 294:1540-1543
    • (2001) Science , vol.294 , pp. 1540-1543
    • Blanco, P.1    Palucka, A.K.2    Gill, M.3    Pascual, V.4    Banchereau, J.5
  • 77
    • 0041429619 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells induce plasma cell differentiation through type i interferon and interleukin 6
    • Jego G, Palucka AK, Blanck JP, Chalouni C, Pascual V, Banchereau J. 2003. Plasmacytoid dendritic cells induce plasma cell differentiation through type I interferon and interleukin 6. Immunity 19:225-234
    • (2003) Immunity , vol.19 , pp. 225-234
    • Jego, G.1    Palucka, A.K.2    Blanck, J.P.3    Chalouni, C.4    Pascual, V.5    Banchereau, J.6
  • 78
    • 0033081259 scopus 로고    scopus 로고
    • Type i interferons keep activated T cells alive
    • Marrack P, Kappler J, Mitchell T. 1999. Type I interferons keep activated T cells alive. J. Exp. Med. 189:521-530
    • (1999) J. Exp. Med. , vol.189 , pp. 521-530
    • Marrack, P.1    Kappler, J.2    Mitchell, T.3
  • 79
    • 24344478196 scopus 로고    scopus 로고
    • Type i interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection
    • Kolumam GA, Thomas S, Thompson LJ, Sprent J, Murali-Krishna K. 2005. Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection. J. Exp. Med. 202:637-650
    • (2005) J. Exp. Med. , vol.202 , pp. 637-650
    • Kolumam, G.A.1    Thomas, S.2    Thompson, L.J.3    Sprent, J.4    Murali-Krishna, K.5
  • 80
    • 0035030376 scopus 로고    scopus 로고
    • Type i interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo
    • Le Bon A, Schiavoni G, D'Agostino G, Gresser I, Belardelli F, Tough DF. 2001. Type I interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo. Immunity 14:461-470
    • (2001) Immunity , vol.14 , pp. 461-470
    • Le Bon, A.1    Schiavoni, G.2    D'Agostino, G.3    Gresser, I.4    Belardelli, F.5    Tough, D.F.6
  • 81
    • 0019972228 scopus 로고
    • Systemic lupus erythematosus: Presence in human serum of an unusual acid-labile leukocyte interferon
    • Preble OT, Black RJ, Friedman RM, Klippel JH, Vilcek J. 1982. Systemic lupus erythematosus: presence in human serum of an unusual acid-labile leukocyte interferon. Science 216:429-431
    • (1982) Science , vol.216 , pp. 429-431
    • Preble, O.T.1    Black, R.J.2    Friedman, R.M.3    Klippel, J.H.4    Vilcek, J.5
  • 82
    • 4344633188 scopus 로고    scopus 로고
    • Update on human systemic lupus erythematosus genetics
    • Tsao BP. 2004. Update on human systemic lupus erythematosus genetics. Curr. Opin. Rheumatol. 16:513-521
    • (2004) Curr. Opin. Rheumatol. , vol.16 , pp. 513-521
    • Tsao, B.P.1
  • 83
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell JE Jr, Kerr IM, Stark GR. 1994. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264:1415-1421
    • (1994) Science , vol.264 , pp. 1415-1421
    • Darnell Jr., J.E.1    Kerr, I.M.2    Stark, G.R.3
  • 84
    • 6344282903 scopus 로고    scopus 로고
    • Induction of genes mediating interferon-dependent extracellular trap formation during neutrophil differentiation
    • Martinelli S, Urosevic M, Daryadel A, Oberholzer PA, Baumann C, et al. 2004. Induction of genes mediating interferon-dependent extracellular trap formation during neutrophil differentiation. J. Biol. Chem. 279:44123-44132
    • (2004) J. Biol. Chem. , vol.279 , pp. 44123-44132
    • Martinelli, S.1    Urosevic, M.2    Daryadel, A.3    Oberholzer, P.A.4    Baumann, C.5
  • 85
    • 34547116656 scopus 로고    scopus 로고
    • Type Iinterferon receptors: Biochemistry and biological functions
    • de Weerd NA, Samarajiwa SA, Hertzog PJ. 2007. Type Iinterferon receptors: biochemistry and biological functions. J. Biol. Chem. 282:20053-20057
    • (2007) J. Biol. Chem. , vol.282 , pp. 20053-20057
    • De Weerd, N.A.1    Samarajiwa, S.A.2    Hertzog, P.J.3
  • 86
    • 0034977353 scopus 로고    scopus 로고
    • Functional classification of interferon-stimulated genes identified using microarrays
    • de Veer MJ, Holko M, Frevel M, Walker E, Der S, et al. 2001. Functional classification of interferon-stimulated genes identified using microarrays. J. Leukoc. Biol. 69:912-920
    • (2001) J. Leukoc. Biol. , vol.69 , pp. 912-920
    • De Veer, M.J.1    Holko, M.2    Frevel, M.3    Walker Der, E.S.4
  • 87
    • 56249101045 scopus 로고    scopus 로고
    • Belimumab, an anti-BLyS human monoclonal antibody for potential treatment of inflammatory autoimmune diseases
    • Ding C. 2008. Belimumab, an anti-BLyS human monoclonal antibody for potential treatment of inflammatory autoimmune diseases. Expert Opin. Biol. Ther. 8:1805-1814
    • (2008) Expert Opin. Biol. Ther. , vol.8 , pp. 1805-1814
    • Ding, C.1
  • 88
    • 0037269787 scopus 로고    scopus 로고
    • Circulating human plasmacytoid dendritic cells are highly sensitive to corticosteroid administration
    • Shodell M, Shah K, Siegal FP. 2003. Circulating human plasmacytoid dendritic cells are highly sensitive to corticosteroid administration. Lupus 12:222-230
    • (2003) Lupus , vol.12 , pp. 222-230
    • Shodell, M.1    Shah, K.2    Siegal, F.P.3
  • 89
    • 3042844142 scopus 로고    scopus 로고
    • Characterization of heterogeneity in the molecular pathogenesis of lupus nephritis from transcriptional profiles of laser-captured glomeruli
    • Peterson KS, Huang JF, Zhu J, D'Agati V, Liu X, et al. 2004. Characterization of heterogeneity in the molecular pathogenesis of lupus nephritis from transcriptional profiles of laser-captured glomeruli. J. Clin. Invest. 113:1722-1733
    • (2004) J. Clin. Invest. , vol.113 , pp. 1722-1733
    • Peterson, K.S.1    Huang, J.F.2    Zhu, J.3    D'Agati, V.4    Liu, X.5
  • 90
    • 34248584526 scopus 로고    scopus 로고
    • Identification of distinct gene expression profiles in the synovium of patients with systemic lupus erythematosus
    • Nzeusseu Toukap A, Galant C, Theate I, Maudoux AL, Lories RJ, et al. 2007. Identification of distinct gene expression profiles in the synovium of patients with systemic lupus erythematosus. Arthritis Rheum. 56:1579-1588
    • (2007) Arthritis Rheum. , vol.56 , pp. 1579-1588
    • Nzeusseu Toukap, A.1    Galant, C.2    Theate, I.3    Maudoux, A.L.4    Lories, R.J.5
  • 91
    • 38149007115 scopus 로고    scopus 로고
    • Glomerular accumulation of plasmacytoid dendritic cells in active lupus nephritis: Role of interleukin-18
    • Tucci M, Quatraro C, Lombardi L, Pellegrino C, Dammacco F, Silvestris F. 2008. Glomerular accumulation of plasmacytoid dendritic cells in active lupus nephritis: role of interleukin-18. Arthritis Rheum. 58:251-262
    • (2008) Arthritis Rheum. , vol.58 , pp. 251-262
    • Tucci, M.1    Quatraro, C.2    Lombardi, L.3    Pellegrino, C.4    Dammacco, F.5    Silvestris, F.6
  • 94
    • 0037320208 scopus 로고    scopus 로고
    • Type i interferon controls the onset and severity of autoimmune manifestations in lpr mice
    • Braun D, Geraldes P, Demengeot J. 2003. Type I interferon controls the onset and severity of autoimmune manifestations in lpr mice. J. Autoimmun. 20:15-25
    • (2003) J. Autoimmun. , vol.20 , pp. 15-25
    • Braun, D.1    Geraldes, P.2    Demengeot, J.3
  • 96
    • 65249108223 scopus 로고    scopus 로고
    • IFNαkinoid vaccine-induced neutralizing antibodies prevent clinical manifestations in a lupus flare murine model
    • Zagury D, Le Buanec H, Mathian A, Larcier P, Burnett R, et al. 2009. IFNα kinoid vaccine-induced neutralizing antibodies prevent clinical manifestations in a lupus flare murine model. Proc. Natl. Acad. Sci. USA 106:5294-5299
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 5294-5299
    • Zagury, D.1    Le Buanec, H.2    Mathian, A.3    Larcier, P.4    Burnett, R.5
  • 100
    • 0034665534 scopus 로고    scopus 로고
    • The combination of apoptotic U937 cells and lupus IgG is a potent IFN-αinducer
    • Bave U, Alm GV, Ronnblom L. 2000. The combination of apoptotic U937 cells and lupus IgG is a potent IFN-α inducer. J. Immunol. 165:3519-3526
    • (2000) J. Immunol. , vol.165 , pp. 3519-3526
    • Bave, U.1    Alm, G.V.2    Ronnblom, L.3
  • 101
    • 28544449709 scopus 로고    scopus 로고
    • Immune stimulation mediated byautoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8
    • Vollmer J, Tluk S, Schmitz C, Hamm S, Jurk M, et al. 2005. Immune stimulation mediated byautoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8. J. Exp. Med. 202:1575-1585
    • (2005) J. Exp. Med. , vol.202 , pp. 1575-1585
    • Vollmer, J.1    Tluk, S.2    Schmitz, C.3    Hamm, S.4    Jurk, M.5
  • 102
    • 26844467349 scopus 로고    scopus 로고
    • Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus
    • Barrat FJ, Meeker T, Gregorio J, Chan JH, Uematsu S, et al. 2005. Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus. J. Exp. Med. 202:1131-1139
    • (2005) J. Exp. Med. , vol.202 , pp. 1131-1139
    • Barrat, F.J.1    Meeker, T.2    Gregorio, J.3    Chan, J.H.4    Uematsu, S.5
  • 103
    • 27744444832 scopus 로고    scopus 로고
    • RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement
    • Lau CM, Broughton C, Tabor AS, Akira S, Flavell RA, et al. 2005. RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement. J. Exp. Med. 202:1171-1177
    • (2005) J. Exp. Med. , vol.202 , pp. 1171-1177
    • Lau, C.M.1    Broughton, C.2    Tabor, A.S.3    Akira, S.4    Flavell, R.A.5
  • 104
    • 36048962438 scopus 로고    scopus 로고
    • Control of Toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation
    • Deane JA, Pisitkun P, Barrett RS, Feigenbaum L, Town T, et al. 2007. Control of Toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation. Immunity 27:801-810
    • (2007) Immunity , vol.27 , pp. 801-810
    • Deane, J.A.1    Pisitkun, P.2    Barrett, R.S.3    Feigenbaum, L.4    Town, T.5
  • 105
    • 67749135880 scopus 로고    scopus 로고
    • Endosomal TLR signaling is required for antinucleic acid and rheumatoid factor autoantibodies in lupus
    • Kono DH, Haraldsson MK, Lawson BR, Pollard KM, Koh YT, et al. 2009. Endosomal TLR signaling is required for antinucleic acid and rheumatoid factor autoantibodies in lupus. Proc. Natl. Acad. Sci. USA 106:12061-12066
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 12061-12066
    • Kono, D.H.1    Haraldsson, M.K.2    Lawson, B.R.3    Pollard, K.M.4    Koh, Y.T.5
  • 107
    • 13844292408 scopus 로고    scopus 로고
    • Polymorphisms in the ty-rosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus
    • Sigurdsson S, Nordmark G, Goring HH, Lindroos K, Wiman AC, et al. 2005. Polymorphisms in the ty-rosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus. Am. J. Hum. Genet. 76:528-537
    • (2005) Am. J. Hum. Genet. , vol.76 , pp. 528-537
    • Sigurdsson, S.1    Nordmark, G.2    Goring, H.H.3    Lindroos, K.4    Wiman, A.C.5
  • 108
    • 33646368404 scopus 로고    scopus 로고
    • A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus
    • Graham RR, Kozyrev SV, Baechler EC, Reddy MV, Plenge RM, et al. 2006. A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus. Nat. Genet. 38:550-555
    • (2006) Nat. Genet. , vol.38 , pp. 550-555
    • Graham, R.R.1    Kozyrev, S.V.2    Baechler, E.C.3    Reddy, M.V.4    Plenge, R.M.5
  • 109
    • 38649125210 scopus 로고    scopus 로고
    • Genome-wide association scaninwomen with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci
    • Harley JB, Alarcon-Riquelme ME, Criswell LA, Jacob CO, Kimberly RP, et al. 2008. Genome-wide association scaninwomen with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat. Genet. 40:204-210
    • (2008) Nat. Genet. , vol.40 , pp. 204-210
    • Harley, J.B.1    Alarcon-Riquelme, M.E.2    Criswell, L.A.3    Jacob, C.O.4    Kimberly, R.P.5
  • 110
    • 49449104525 scopus 로고    scopus 로고
    • Association of the IRF5 risk haplotype with high serum interferon-α activity in systemic lupus erythematosus patients
    • Niewold TB, Kelly JA, Flesch MH, Espinoza LR, Harley JB, Crow MK. 2008. Association of the IRF5 risk haplotype with high serum interferon-α activity in systemic lupus erythematosus patients. Arthritis Rheum. 58:2481-2487
    • (2008) Arthritis Rheum. , vol.58 , pp. 2481-2487
    • Niewold, T.B.1    Kelly, J.A.2    Flesch, M.H.3    Espinoza, L.R.4    Harley, J.B.5    Crow, M.K.6
  • 111
    • 34548438559 scopus 로고    scopus 로고
    • High serum IFN-a activity is a heritable risk factor for systemic lupus erythematosus
    • Niewold TB, Hua J, Lehman TJ, Harley JB, CrowMK. 2007. High serum IFN-a activity is a heritable risk factor for systemic lupus erythematosus. Genes Immun. 8:492-502
    • (2007) Genes Immun. , vol.8 , pp. 492-502
    • Niewold, T.B.1    Hua, J.2    Lehman, T.J.3    Harley, J.B.4    Crow, M.K.5
  • 112
    • 34548427925 scopus 로고    scopus 로고
    • STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus
    • Remmers EF, Plenge RM, Lee AT, Graham RR, Hom G, et al. 2007. STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus. N. Engl. J. Med. 357:977-986
    • (2007) N. Engl. J. Med. , vol.357 , pp. 977-986
    • Remmers, E.F.1    Plenge, R.M.2    Lee, A.T.3    Graham, R.R.4    Hom, G.5
  • 113
    • 37149034017 scopus 로고    scopus 로고
    • Identification of novel susceptibility genes in childhood-onset systemic lupus erythematosus using a uniquely designed candidate gene pathway platform
    • Jacob CO, Reiff A, Armstrong DL, Myones BL, Silverman E, et al. 2007. Identification of novel susceptibility genes in childhood-onset systemic lupus erythematosus using a uniquely designed candidate gene pathway platform. Arthritis Rheum. 56:4164-4173
    • (2007) Arthritis Rheum. , vol.56 , pp. 4164-4173
    • Jacob, C.O.1    Reiff, A.2    Armstrong, D.L.3    Myones, B.L.4    Silverman, E.5
  • 114
    • 65549124475 scopus 로고    scopus 로고
    • Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus
    • Jacob CO, Zhu J, Armstrong DL, YanM, Han J, et al. 2009. Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus. Proc. Natl. Acad. Sci. USA 106:6256-6261
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 6256-6261
    • Jacob, C.O.1    Zhu, J.2    Armstrong, D.L.3    Yanm Han, J.4
  • 115
    • 34147185679 scopus 로고    scopus 로고
    • Heterozygous mutations in TREX1 cause familial chilblain lupus and dominant Aicardi-Goutieres syndrome
    • Rice G, Newman WG, Dean J, Patrick T, Parmar R, et al. 2007. Heterozygous mutations in TREX1 cause familial chilblain lupus and dominant Aicardi-Goutieres syndrome. Am. J. Hum. Genet. 80:811-815
    • (2007) Am. J. Hum. Genet. , vol.80 , pp. 811-815
    • Rice, G.1    Newman, W.G.2    Dean, J.3    Patrick, T.4    Parmar, R.5
  • 116
    • 34548327158 scopus 로고    scopus 로고
    • Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus
    • Lee-Kirsch MA, Gong M, Chowdhury D, Senenko L, Engel K, et al. 2007. Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus. Nat. Genet. 39:1065-1067
    • (2007) Nat. Genet. , vol.39 , pp. 1065-1067
    • Lee-Kirsch, M.A.1    Gong, M.2    Chowdhury, D.3    Senenko, L.4    Engel, K.5
  • 117
    • 49549100511 scopus 로고    scopus 로고
    • Trex1 prevents cell-intrinsic initiation of autoimmunity
    • Stetson DB, Ko JS, Heidmann T, Medzhitov R 2008. Trex1 prevents cell-intrinsic initiation of autoimmunity. Cell 134:587-598
    • (2008) Cell , vol.134 , pp. 587-598
    • Stetson, D.B.1    Ko, J.S.2    Heidmann, T.3    Medzhitov, R.4
  • 118
    • 57649134251 scopus 로고    scopus 로고
    • TheTREX1 double-stranded DNA degradation activity is defective in dominant mutations associated with autoimmune disease
    • Lehtinen DA, Harvey S, MulcahyMJ, HollisT, PerrinoFW. 2008. TheTREX1 double-stranded DNA degradation activity is defective in dominant mutations associated with autoimmune disease. J. Biol. Chem. 283:31649-31656
    • (2008) J. Biol. Chem. , vol.283 , pp. 31649-31656
    • Lehtinen, D.A.1    Harvey, S.2    Hollist, M.3    Perrino, F.W.4
  • 119
    • 62449110463 scopus 로고    scopus 로고
    • Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling
    • Tal MC, Sasai M, Lee HK, Yordy B, Shadel GS, Iwasaki A. 2009. Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling. Proc. Natl. Acad. Sci. USA 106:2770-2775
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 2770-2775
    • Tal, M.C.1    Sasai, M.2    Lee, H.K.3    Yordy, B.4    Shadel, G.S.5    Iwasaki, A.6
  • 120
    • 67849099131 scopus 로고    scopus 로고
    • Recent insights into the genetic basis of systemic lupus erythematosus
    • Moser KL, Kelly JA, Lessard CJ, Harley JB. 2009. Recent insights into the genetic basis of systemic lupus erythematosus. Genes. Immun. 10:373-379
    • (2009) Genes. Immun. , vol.10 , pp. 373-379
    • Moser, K.L.1    Kelly, J.A.2    Lessard, C.J.3    Harley, J.B.4
  • 122
    • 0035881627 scopus 로고    scopus 로고
    • Increased frequency of pregerminal center B cells and plasma cell precursors in the blood of children with systemic lupus erythematosus
    • Arce E, Jackson DG, Gill MA, Bennett LB, Banchereau J, Pascual V. 2001. Increased frequency of pregerminal center B cells and plasma cell precursors in the blood of children with systemic lupus erythematosus. J. Immunol. 167:2361-2369
    • (2001) J. Immunol. , vol.167 , pp. 2361-2369
    • Arce, E.1    Jackson, D.G.2    Gill, M.A.3    Bennett, L.B.4    Banchereau, J.5    Pascual, V.6
  • 123
    • 0034669990 scopus 로고    scopus 로고
    • Disturbed peripheral B lymphocyte homeostasis in systemic lupus erythematosus
    • Odendahl M, Jacobi A, Hansen A, Feist E, Hiepe F, et al. 2000. Disturbed peripheral B lymphocyte homeostasis in systemic lupus erythematosus. J. Immunol. 165:5970-5979
    • (2000) J. Immunol. , vol.165 , pp. 5970-5979
    • Odendahl, M.1    Jacobi, A.2    Hansen, A.3    Feist, E.4    Hiepe, F.5
  • 124
    • 44449118948 scopus 로고    scopus 로고
    • Rapid cloning of high-affinity human monoclonal antibodies against influenza virus
    • Wrammert J, Smith K, Miller J, Langley WA, Kokko K, et al. 2008. Rapid cloning of high-affinity human monoclonal antibodies against influenza virus. Nature 453:667-671
    • (2008) Nature , vol.453 , pp. 667-671
    • Wrammert, J.1    Smith, K.2    Miller, J.3    Langley, W.A.4    Kokko, K.5
  • 125
    • 66449097622 scopus 로고    scopus 로고
    • Neutralization of interferon-a/|3-inducible genes and downstream effect in a phase i trial of an anti-interferon-a monoclonal antibody in systemic lupus erythematosus
    • Yao Y, Richman L, Higgs BW, Morehouse CA, de los Reyes M, et al. 2009. Neutralization of interferon-a/|3-inducible genes and downstream effect in a phase I trial of an anti-interferon-a monoclonal antibody in systemic lupus erythematosus. Arthritis Rheum. 60:1785-1796
    • (2009) Arthritis Rheum. , vol.60 , pp. 1785-1796
    • Yao, Y.1    Richman, L.2    Higgs, B.W.3    Morehouse, C.A.4    De Los Reyes, M.5
  • 126
    • 0029876228 scopus 로고    scopus 로고
    • Dynamics of fever and the cytokine network in systemic juvenile arthritis
    • Prieur AM, Roux-Lombard P, Dayer JM. 1996. Dynamics of fever and the cytokine network in systemic juvenile arthritis. Rev. Rhum. (Engl. Ed.) 63:163-170
    • (1996) Rev. Rhum. (Engl. Ed.) , vol.63 , pp. 163-170
    • Prieur, A.M.1    Roux-Lombard, P.2    Dayer, J.M.3
  • 127
    • 0346340916 scopus 로고    scopus 로고
    • Inflammatory cytokines and cytokine antagonists in whole blood cultures of patients with systemic juvenile chronic arthritis
    • Muller K, Herner EB, Stagg A, Bendtzen K, Woo P. 1998. Inflammatory cytokines and cytokine antagonists in whole blood cultures of patients with systemic juvenile chronic arthritis. Br. J. Rheumatol. 37:562-569
    • (1998) Br. J. Rheumatol. , vol.37 , pp. 562-569
    • Muller, K.1    Herner, E.B.2    Stagg, A.3    Bendtzen, K.4    Woo, P.5
  • 129
    • 0029979369 scopus 로고    scopus 로고
    • Biologic basis for interleukin-1 in disease
    • Dinarello CA. 1996. Biologic basis for interleukin-1 in disease. Blood 87:2095-2147
    • (1996) Blood , vol.87 , pp. 2095-2147
    • Dinarello, C.A.1
  • 130
    • 57349086217 scopus 로고    scopus 로고
    • S100A12 is a novel molecular marker differentiating systemic-onset juvenile idiopathic arthritis from other causes of fever of unknown origin
    • Wittkowski H, Frosch M, Wulffraat N, Goldbach-Mansky R, Kallinich T, et al. 2008. S100A12 is a novel molecular marker differentiating systemic-onset juvenile idiopathic arthritis from other causes of fever of unknown origin. Arthritis Rheum. 58:3924-3931
    • (2008) Arthritis Rheum. , vol.58 , pp. 3924-3931
    • Wittkowski, H.1    Frosch, M.2    Wulffraat, N.3    Goldbach-Mansky, R.4    Kallinich, T.5
  • 131
    • 61749104104 scopus 로고    scopus 로고
    • The myeloid-related proteins 8 and 14 complex, a novel ligand of Toll-like receptor 4, and interleukin-113 form a positive feedback mechanism in systemic-onset juvenile idiopathic arthritis
    • Frosch M, Ahlmann M, Vogl T, Wittkowski H, Wulffraat N, et al. 2009. The myeloid-related proteins 8 and 14 complex, a novel ligand of Toll-like receptor 4, and interleukin-113 form a positive feedback mechanism in systemic-onset juvenile idiopathic arthritis. Arthritis Rheum. 60:883-891
    • (2009) Arthritis Rheum. , vol.60 , pp. 883-891
    • Frosch, M.1    Ahlmann, M.2    Vogl, T.3    Wittkowski, H.4    Wulffraat, N.5
  • 132
    • 42549147098 scopus 로고    scopus 로고
    • Variant form of STAT4 is associated with primary Sjogren's syndrome
    • Korman BD, Alba MI, Le JM, Alevizos I, Smith JA, et al. 2008. Variant form of STAT4 is associated with primary Sjogren's syndrome. Genes Immun. 9:267-270
    • (2008) Genes Immun. , vol.9 , pp. 267-270
    • Korman, B.D.1    Alba, M.I.2    Le Jm Alevizos, I.3    Smith, J.A.4
  • 133
    • 59149104204 scopus 로고    scopus 로고
    • Additive effects of the major risk alleles of IRF5 and STAT4 in primary Sjogren's syndrome
    • Nordmark G, Kristjansdottir G, Theander E, Eriksson P, Brun JG, et al. 2009. Additive effects of the major risk alleles of IRF5 and STAT4 in primary Sjogren's syndrome. Genes Immun. 10:68-76
    • (2009) Genes Immun. , vol.10 , pp. 68-76
    • Nordmark, G.1    Kristjansdottir, G.2    Theander, E.3    Eriksson, P.4    Brun, J.G.5
  • 134
    • 18644364840 scopus 로고    scopus 로고
    • Gene expression profiling of minor salivary glands clearly distinguishes primary Sjogren's syndrome patients from healthy control subjects
    • Hjelmervik TO, Petersen K, Jonassen I, Jonsson R, Bolstad AI. 2005. Gene expression profiling of minor salivary glands clearly distinguishes primary Sjogren's syndrome patients from healthy control subjects. Arthritis Rheum. 52:1534-1544
    • (2005) Arthritis Rheum. , vol.52 , pp. 1534-1544
    • Hjelmervik, T.O.1    Petersen, K.2    Jonassen, I.3    Jonsson, R.4    Bolstad, A.I.5
  • 136
    • 34948848066 scopus 로고    scopus 로고
    • A gene expression approach to study perturbed pathways in myositis
    • Greenberg SA. 2007. A gene expression approach to study perturbed pathways in myositis. Curr. Opin. Rheumatol. 19:536-541
    • (2007) Curr. Opin. Rheumatol. , vol.19 , pp. 536-541
    • Greenberg, S.A.1
  • 137
    • 0021176654 scopus 로고
    • Monoclonal antibody analysis of mononuclear cells in myopathies. I: Quan-titation of subsets according to diagnosis and sites of accumulation and demonstration and counts of muscle fibers invaded by T cells
    • Arahata K, Engel AG. 1984. Monoclonal antibody analysis of mononuclear cells in myopathies. I: Quan-titation of subsets according to diagnosis and sites of accumulation and demonstration and counts of muscle fibers invaded by T cells. Ann. Neurol. 16:193-208
    • (1984) Ann. Neurol. , vol.16 , pp. 193-208
    • Arahata, K.1    Engel, A.G.2
  • 138
    • 33744475615 scopus 로고    scopus 로고
    • Type i interferon-associated skin recruitment of CXCR3+ lymphocytes in dermatomyositis
    • Wenzel J, Schmidt R, Proelss J, Zahn S, Bieber T, Tuting T. 2006. Type I interferon-associated skin recruitment of CXCR3+ lymphocytes in dermatomyositis. Clin. Exp. Dermatol. 31:576-582
    • (2006) Clin. Exp. Dermatol. , vol.31 , pp. 576-582
    • Wenzel, J.1    Schmidt, R.2    Proelss, J.3    Zahn, S.4    Bieber, T.5    Tuting, T.6
  • 139
    • 45949111522 scopus 로고    scopus 로고
    • Juvenile dermatomyositis and other idiopathic inflammatory myopathies of childhood
    • Feldman BM, Rider LG, Reed AM, Pachman LM. 2008. Juvenile dermatomyositis and other idiopathic inflammatory myopathies of childhood. Lancet 371:2201-2212
    • (2008) Lancet , vol.371 , pp. 2201-2212
    • Feldman, B.M.1    Rider, L.G.2    Reed, A.M.3    Pachman, L.M.4
  • 141
    • 34948900717 scopus 로고    scopus 로고
    • Type i interferon-inducible gene expression in blood is present and reflects disease activity in dermatomyositis and polymyositis
    • Walsh RJ, Kong SW, Yao Y, Jallal B, Kiener PA, et al. 2007. Type I interferon-inducible gene expression in blood is present and reflects disease activity in dermatomyositis and polymyositis. Arthritis Rheum. 56:3784-3792
    • (2007) Arthritis Rheum. , vol.56 , pp. 3784-3792
    • Walsh, R.J.1    Kong, S.W.2    Yao, Y.3    Jallal, B.4    Kiener, P.A.5
  • 142
    • 33847279025 scopus 로고    scopus 로고
    • Pathogenesis and therapy of psoriasis
    • Lowes MA, Bowcock AM, Krueger JG. 2007. Pathogenesis and therapy of psoriasis. Nature 445:866-873
    • (2007) Nature , vol.445 , pp. 866-873
    • Lowes, M.A.1    Bowcock, A.M.2    Krueger, J.G.3
  • 143
    • 0035756813 scopus 로고    scopus 로고
    • Molecular classification of psoriasis disease-associated genes through pharmacogenomic expression profiling
    • Oestreicher JL, Walters IB, Kikuchi T, Gilleaudeau P, Surette J, et al. 2001. Molecular classification of psoriasis disease-associated genes through pharmacogenomic expression profiling. Pharmacogenomics J. 1:272-287
    • (2001) Pharmacogenomics J. , vol.1 , pp. 272-287
    • Oestreicher, J.L.1    Walters, I.B.2    Kikuchi, T.3    Gilleaudeau, P.4    Surette, J.5
  • 144
    • 0346995201 scopus 로고    scopus 로고
    • Distinct patterns of gene expression in the skin lesions of atopic dermatitis and psoriasis: A gene microarray analysis
    • Nomura I, Gao B, Boguniewicz M, Darst MA, Travers JB, Leung DY. 2003. Distinct patterns of gene expression in the skin lesions of atopic dermatitis and psoriasis: a gene microarray analysis. J. Allergy Clin. Immunol. 112:1195-1202
    • (2003) J. Allergy Clin. Immunol. , vol.112 , pp. 1195-1202
    • Nomura, I.1    Gao, B.2    Boguniewicz, M.3    Darst, M.A.4    Travers, J.B.5    Leung, D.Y.6
  • 145
    • 0035880456 scopus 로고    scopus 로고
    • Insights into psoriasis and other inflammatory diseases from large-scale gene expression studies
    • Bowcock AM, Shannon W, Du F, Duncan J, Cao K, et al. 2001. Insights into psoriasis and other inflammatory diseases from large-scale gene expression studies. Hum. Mol. Genet. 10:1793-1805
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 1793-1805
    • Bowcock, A.M.1    Shannon, W.2    Du, F.3    Duncan, J.4    Cao, K.5
  • 146
    • 0037453146 scopus 로고    scopus 로고
    • Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63100-element oligonucleotide array
    • Zhou X, Krueger JG, Kao MC, Lee E, Du F, et al. 2003. Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63100-element oligonucleotide array. Physiol. Genomics 13:69-78
    • (2003) Physiol. Genomics , vol.13 , pp. 69-78
    • Zhou, X.1    Krueger, J.G.2    Kao, M.C.3    Lee, E.4    Du, F.5
  • 147
    • 66149094262 scopus 로고    scopus 로고
    • The immunopathogenesis of rheumatoid arthritis
    • Imboden JB. 2009. The immunopathogenesis of rheumatoid arthritis. Annu. Rev. Pathol. 4:417-434
    • (2009) Annu. Rev. Pathol. , vol.4 , pp. 417-434
    • Imboden, J.B.1
  • 148
    • 19944362145 scopus 로고    scopus 로고
    • DNA microarray allows molecular profiling ofrheumatoid arthritis and identificationof pathophysiological targets
    • Devauchelle V, Marion S, Cagnard N, Mistou S, Falgarone G, et al. 2004. DNA microarray allows molecular profiling ofrheumatoid arthritis and identificationof pathophysiological targets. Genes Immun. 5:597-608
    • (2004) Genes Immun. , vol.5 , pp. 597-608
    • Devauchelle, V.1    Marion, S.2    Cagnard, N.3    Mistou, S.4    Falgarone, G.5
  • 149
    • 0042655250 scopus 로고    scopus 로고
    • Rheumatoid arthritis is a heterogeneous disease: Evidence for differences in the activation of the STAT-1 pathway between rheumatoid tissues
    • Van Der Pouw Kraan TC, van Gaalen FA, Kasperkovitz PV, Verbeet NL, Smeets TJ, et al. 2003. Rheumatoid arthritis is a heterogeneous disease: evidence for differences in the activation of the STAT-1 pathway between rheumatoid tissues. Arthritis Rheum. 48:2132-2145
    • (2003) Arthritis Rheum. , vol.48 , pp. 2132-2145
    • Van Der Pouw Kraan, T.C.1    Van Gaalen, F.A.2    Kasperkovitz, P.V.3    Verbeet, N.L.4    Smeets, T.J.5
  • 150
    • 41849115276 scopus 로고    scopus 로고
    • Responsiveness to antitumor necrosis factor α therapy is related to pretreatment tissue inflammation levels in rheumatoid arthritis patients
    • Van Der Pouw Kraan TC, Wijbrandts CA, van Baarsen LG, Rustenburg F, Baggen JM, et al. 2008. Responsiveness to antitumor necrosis factor α therapy is related to pretreatment tissue inflammation levels in rheumatoid arthritis patients. Ann. Rheum. Dis. 67:563-566
    • (2008) Ann. Rheum. Dis. , vol.67 , pp. 563-566
    • Van Der Pouw Kraan, T.C.1    Wijbrandts, C.A.2    Van Baarsen, L.G.3    Rustenburg, F.4    Baggen, J.M.5
  • 153
    • 67349269613 scopus 로고    scopus 로고
    • Molecular subtypes of systemic sclerosis in association with anticentromere antibodies and digital ulcers
    • Bos CL, van Baarsen LG, Timmer TC, Overbeek MJ, Basoski NM, et al. 2009. Molecular subtypes of systemic sclerosis in association with anticentromere antibodies and digital ulcers. Genes. Immun. 10:210-218
    • (2009) Genes. Immun. , vol.10 , pp. 210-218
    • Bos, C.L.1    Van Baarsen, L.G.2    Timmer, T.C.3    Overbeek, M.J.4    Basoski, N.M.5
  • 154
    • 65549154046 scopus 로고    scopus 로고
    • The STAT4 gene influences the genetic predisposition to systemic sclerosis phenotype
    • Rueda B, Broen J, Simeon C, Hesselstrand R, Diaz B, et al. 2009. The STAT4 gene influences the genetic predisposition to systemic sclerosis phenotype. Hum. Mol. Genet. 18:2071-2077
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 2071-2077
    • Rueda, B.1    Broen, J.2    Simeon, C.3    Hesselstrand, R.4    Diaz, B.5
  • 155
    • 33644607018 scopus 로고    scopus 로고
    • Multiple sclerosis-the plaque and its pathogenesis
    • Frohman EM, Racke MK, Raine CS. 2006. Multiple sclerosis-the plaque and its pathogenesis. N. Engl. J. Med. 354:942-955
    • (2006) N. Engl. J. Med. , vol.354 , pp. 942-955
    • Frohman, E.M.1    Racke, M.K.2    Raine, C.S.3
  • 156
    • 0242432319 scopus 로고    scopus 로고
    • CDNA microarray analysis in multiple sclerosis lesions: Detection of genes associated with disease activity
    • Mycko MP, Papoian R, Boschert U, Raine CS, Selmaj KW. 2003. cDNA microarray analysis in multiple sclerosis lesions: detection of genes associated with disease activity. Brain 126:1048-1057
    • (2003) Brain , vol.126 , pp. 1048-1057
    • Mycko, M.P.1    Papoian, R.2    Boschert, U.3    Raine, C.S.4    Selmaj, K.W.5
  • 157
    • 2642539885 scopus 로고    scopus 로고
    • Microarray gene expression profiling of chronic active and inactive lesions in multiple sclerosis
    • Mycko MP, Papoian R, Boschert U, Raine CS, Selmaj KW. 2004. Microarray gene expression profiling of chronic active and inactive lesions in multiple sclerosis. Clin. Neurol. Neurosurg. 106:223-229
    • (2004) Clin. Neurol. Neurosurg. , vol.106 , pp. 223-229
    • Mycko, M.P.1    Papoian, R.2    Boschert, U.3    Raine, C.S.4    Selmaj, K.W.5
  • 158
    • 1842687455 scopus 로고    scopus 로고
    • Microarray detection of E2F pathway activation and other targets in multiple sclerosis peripheral blood mononuclear cells
    • Iglesias AH, Camelo S, Hwang D, Villanueva R, Stephanopoulos G, Dangond F. 2004. Microarray detection of E2F pathway activation and other targets in multiple sclerosis peripheral blood mononuclear cells. J. Neuroimmunol. 150:163-177
    • (2004) J. Neuroimmunol. , vol.150 , pp. 163-177
    • Iglesias, A.H.1    Camelo, S.2    Hwang, D.3    Villanueva, R.4    Stephanopoulos, G.5    Dangond, F.6
  • 159
    • 20044383560 scopus 로고    scopus 로고
    • Microarray analysis identifies an aberrant expression of apoptosis and DNA damage-regulatory genes in multiple sclerosis
    • Satoh J, Nakanishi M, Koike F, Miyake S, Yamamoto T, et al. 2005. Microarray analysis identifies an aberrant expression of apoptosis and DNA damage-regulatory genes in multiple sclerosis. Neurobiol. Dis. 18:537-550
    • (2005) Neurobiol. Dis. , vol.18 , pp. 537-550
    • Satoh, J.1    Nakanishi, M.2    Koike, F.3    Miyake, S.4    Yamamoto, T.5
  • 160
    • 0038546727 scopus 로고    scopus 로고
    • Microarray analysis identifies interferon beta-regulated genes in multiple sclerosis
    • Koike F, Satoh J, Miyake S, Yamamoto T, Kawai M, et al. 2003. Microarray analysis identifies interferon beta-regulated genes in multiple sclerosis. J. Neuroimmunol. 139:109-118
    • (2003) J. Neuroimmunol. , vol.139 , pp. 109-118
    • Koike, F.1    Satoh, J.2    Miyake, S.3    Yamamoto, T.4    Kawai, M.5
  • 161
    • 0038692013 scopus 로고    scopus 로고
    • Expression profiling identifies responder and nonresponder phenotypes to interferon-beta in multiple sclerosis
    • Sturzebecher S, Wandinger KP, Rosenwald A, Sathyamoorthy M, Tzou A, et al. 2003. Expression profiling identifies responder and nonresponder phenotypes to interferon-beta in multiple sclerosis. Brain 126:1419-1429
    • (2003) Brain , vol.126 , pp. 1419-1429
    • Sturzebecher, S.1    Wandinger, K.P.2    Rosenwald, A.3    Sathyamoorthy, M.4    Tzou, A.5
  • 162
    • 68849107852 scopus 로고    scopus 로고
    • Longitudinal system-based analysis of transcriptional responses to type i interferons
    • Pappas DJ, Coppola G, Gabatto PA, Gao F, Geschwind DH, et al. 2009. Longitudinal system-based analysis of transcriptional responses to type I interferons. Physiol. Genomics 38:362-371
    • (2009) Physiol. Genomics , vol.38 , pp. 362-371
    • Pappas, D.J.1    Coppola, G.2    Gabatto, P.A.3    Gao, F.4    Geschwind, D.H.5
  • 163
    • 0029036567 scopus 로고
    • Interferon expression in the pancreases of patients with type i diabetes
    • Huang X, Yuang J, Goddard A, Foulis A, James RF, et al. 1995. Interferon expression in the pancreases of patients with type I diabetes. Diabetes 44:658-664
    • (1995) Diabetes , vol.44 , pp. 658-664
    • Huang, X.1    Yuang, J.2    Goddard, A.3    Foulis, A.4    James, R.F.5
  • 166
    • 0001930285 scopus 로고    scopus 로고
    • Juvenile rheumatoid arthritis
    • ed. JT Cassidy, RE Petty, pp. Philadelphia: W. B. Saunders. 3rd ed
    • Cassidy JT, Petty RE. 2001. Juvenile rheumatoid arthritis. In Textbook of Pediatric Rheumatology, ed. JT Cassidy, RE Petty, pp. 218-321. Philadelphia: W. B. Saunders. 3rd ed.
    • (2001) Textbook of Pediatric Rheumatology , pp. 218-321
    • Cassidy, J.T.1    Petty, R.E.2
  • 167
    • 33745484802 scopus 로고    scopus 로고
    • Analysis of significance patterns identifies ubiquitous and disease-specific gene-expression signatures in patient peripheral blood leukocytes
    • Chaussabel D, Allman W, Mejias A, Chung W, Bennett L, et al. 2005. Analysis of significance patterns identifies ubiquitous and disease-specific gene-expression signatures in patient peripheral blood leukocytes. Ann. N. Y. Acad. Sci. 1062:146-154
    • (2005) Ann. N. Y. Acad. Sci. , vol.1062 , pp. 146-154
    • Chaussabel, D.1    Allman, W.2    Mejias, A.3    Chung, W.4    Bennett, L.5
  • 168
    • 10744224439 scopus 로고    scopus 로고
    • Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria
    • Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, et al. 2003. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115:629-640
    • (2003) Cell , vol.115 , pp. 629-640
    • Mootha, V.K.1    Bunkenborg, J.2    Olsen, J.V.3    Hjerrild, M.4    Wisniewski, J.R.5
  • 169
    • 2442446708 scopus 로고    scopus 로고
    • Genome-wide discovery of transcriptional modules from DNA sequence and gene expression
    • Segal E, Yelensky R, Koller D. 2003. Genome-wide discovery of transcriptional modules from DNA sequence and gene expression. Bioinformatics 19(Suppl. 1):i273-82
    • (2003) Bioinformatics , vol.19 , Issue.SUPPL. 1
    • Segal, E.1    Yelensky, R.2    Koller, D.3
  • 170
    • 29244448340 scopus 로고    scopus 로고
    • Microarray data analysis: From disarray to consolidation and consensus
    • Allison DB, Cui X, Page GP, Sabripour M. 2006. Microarray data analysis: from disarray to consolidation and consensus. Nat. Rev. Genet. 7:55-65
    • (2006) Nat. Rev. Genet. , vol.7 , pp. 55-65
    • Allison, D.B.1    Cui, X.2    Page, G.P.3    Sabripour, M.4
  • 171
    • 50949084896 scopus 로고    scopus 로고
    • Geometric interpretation of gene coexpression network analysis
    • Horvath S, Dong J. 2008. Geometric interpretation of gene coexpression network analysis. PLoS Comput. Biol. 4:e1000117
    • (2008) PLoS Comput. Biol. , vol.4
    • Horvath, S.1    Dong, J.2
  • 172
    • 46749152178 scopus 로고    scopus 로고
    • A modular analysis framework for blood genomics studies: Application to systemic lupus erythematosus
    • Chaussabel D, Quinn C, Shen J, Patel P, Glaser C, et al. 2008. A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus. Immunity 29:150-164
    • (2008) Immunity , vol.29 , pp. 150-164
    • Chaussabel, D.1    Quinn, C.2    Shen, J.3    Patel, P.4    Glaser, C.5
  • 173
    • 0024419180 scopus 로고
    • Reliability and validity of six systems for the clinical assessment of disease activity in systemic lupus erythematosus
    • Liang MH, Socher SA, Larson MG, Schur PH. 1989. Reliability and validity of six systems for the clinical assessment of disease activity in systemic lupus erythematosus. Arthritis Rheum. 32:1107-1118
    • (1989) Arthritis Rheum. , vol.32 , pp. 1107-1118
    • Liang, M.H.1    Socher, S.A.2    Larson, M.G.3    Schur, P.H.4
  • 174
    • 0036158415 scopus 로고    scopus 로고
    • Systemic lupus erythematosus disease activity index 2000
    • Gladman DD, Ibanez D, Urowitz MB. 2002. Systemic lupus erythematosus disease activity index 2000. J. Rheumatol. 29:288-291
    • (2002) J. Rheumatol. , vol.29 , pp. 288-291
    • Gladman, D.D.1    Ibanez, D.2    Urowitz, M.B.3
  • 175
  • 177
    • 33646087412 scopus 로고    scopus 로고
    • A highly standardized, robust, and cost-effective method for genome-wide transcriptome analysis of peripheral blood applicable to large-scale clinical trials
    • Debey S, Zander T, Brors B, Popov A, Eils R, Schultze JL. 2006. A highly standardized, robust, and cost-effective method for genome-wide transcriptome analysis of peripheral blood applicable to large-scale clinical trials. Genomics 87:653-664
    • (2006) Genomics , vol.87 , pp. 653-664
    • Debey, S.1    Zander, T.2    Brors, B.3    Popov, A.4    Eils, R.5    Schultze, J.L.6
  • 178
    • 58149289754 scopus 로고    scopus 로고
    • RNA stabilization of peripheral blood and profiling by bead chip analysis
    • Debey-Pascher S, Eggle D, Schultze JL. 2009. RNA stabilization of peripheral blood and profiling by bead chip analysis. Methods Mol. Biol. 496:175-210
    • (2009) Methods Mol. Biol. , vol.496 , pp. 175-210
    • Debey-Pascher, S.1    Eggle, D.2    Schultze, J.L.3
  • 179
    • 65449163005 scopus 로고    scopus 로고
    • A practical platform for blood biomarker study by using global gene expression profiling of peripheral whole blood
    • Tian Z, Palmer N, Schmid P, Yao H, Galdzicki M, et al. 2009. A practical platform for blood biomarker study by using global gene expression profiling of peripheral whole blood. PLoS One 4:e5157
    • (2009) PLoS One , vol.4
    • Tian, Z.1    Palmer, N.2    Schmid, P.3    Yao, H.4    Galdzicki, M.5
  • 180
    • 61649109505 scopus 로고    scopus 로고
    • Gene expression profiling of whole blood: Comparisonoftarget preparation methods for accurate and reproducible microarray analysis
    • Vartanian K, Slottke R, Johnstone T, Casale A, Planck SR, et al. 2009. Gene expression profiling of whole blood: comparisonoftarget preparation methods for accurate and reproducible microarray analysis. BMC Genomics 10:2
    • (2009) BMC Genomics , vol.10 , pp. 2
    • Vartanian, K.1    Slottke, R.2    Johnstone, T.3    Casale, A.4    Planck, S.R.5
  • 181
    • 38749116228 scopus 로고    scopus 로고
    • Interference of globin genes with biomarker discovery for allograft rejection in peripheral blood samples
    • Li L, Ying L, Naesens M, Xiao W, Sigdel T, et al. 2008. Interference of globin genes with biomarker discovery for allograft rejection in peripheral blood samples. Physiol. Genomics 32:190-197
    • (2008) Physiol. Genomics , vol.32 , pp. 190-197
    • Li, L.1    Ying, L.2    Naesens, M.3    Xiao, W.4    Sigdel, T.5
  • 182
    • 33748491517 scopus 로고    scopus 로고
    • The MicroArray Quality Control (MAQC) project shows inter-and intraplatform reproducibility of gene expression measurements
    • Shi L, Reid LH, Jones WD, Shippy R, Warrington JA, et al. 2006. The MicroArray Quality Control (MAQC) project shows inter-and intraplatform reproducibility of gene expression measurements. Nat. Biotechnol. 24:1151-1161
    • (2006) Nat. Biotechnol. , vol.24 , pp. 1151-1161
    • Shi, L.1    Reid, L.H.2    Jones, W.D.3    Shippy, R.4    Warrington, J.A.5
  • 183
    • 39149111585 scopus 로고    scopus 로고
    • Reproducible and reliable microarray results through quality control: Good laboratory proficiency and appropriate data analysis practices are essential
    • Shi L, Perkins RG, Fang H, Tong W. 2008. Reproducible and reliable microarray results through quality control: good laboratory proficiency and appropriate data analysis practices are essential. Curr. Opin. Biotechnol. 19:10-18
    • (2008) Curr. Opin. Biotechnol. , vol.19 , pp. 10-18
    • Shi, L.1    Perkins, R.G.2    Fang, H.3    Tong, W.4
  • 184
    • 0141905890 scopus 로고    scopus 로고
    • Evaluation of gene expression measurements from commercial microarray platforms
    • Tan PK, Downey TJ, Spitznagel EL Jr, Xu P, Fu D, et al. 2003. Evaluation of gene expression measurements from commercial microarray platforms. Nucleic Acids Res. 31:5676-5684
    • (2003) Nucleic Acids Res. , vol.31 , pp. 5676-5684
    • Tan, P.K.1    Downey, T.J.2    Spitznagel Jr., E.L.3    Xu, P.4    Fu, D.5
  • 185
    • 30544439504 scopus 로고    scopus 로고
    • Creation and implications of a phenome-genome network
    • Butte AJ, Kohane IS. 2006. Creation and implications of a phenome-genome network. Nat. Biotechnol. 24:55-62
    • (2006) Nat. Biotechnol. , vol.24 , pp. 55-62
    • Butte, A.J.1    Kohane, I.S.2
  • 186
    • 3042694117 scopus 로고    scopus 로고
    • Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression
    • Rhodes DR, Yu J, Shanker K, Deshpande N, Varambally R, et al. 2004. Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression. Proc. Natl. Acad. Sci. USA 101:9309-9314
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 9309-9314
    • Rhodes, D.R.1    Yu, J.2    Shanker, K.3    Deshpande, N.4    Varambally, R.5
  • 189
    • 62849094483 scopus 로고    scopus 로고
    • Navigating the network: Signaling cross-talk in hematopoietic cells
    • Fraser ID, Germain RN. 2009. Navigating the network: signaling cross-talk in hematopoietic cells. Nat. Immunol. 10:327-331
    • (2009) Nat. Immunol. , vol.10 , pp. 327-331
    • Fraser, I.D.1    Germain, R.N.2
  • 190
    • 58049203835 scopus 로고    scopus 로고
    • Systems biology of innate immunity
    • Zak DE, Aderem A. 2009. Systems biology of innate immunity. Immunol. Rev. 227:264-282
    • (2009) Immunol. Rev. , vol.227 , pp. 264-282
    • Zak, D.E.1    Aderem, A.2
  • 191
    • 40449100030 scopus 로고    scopus 로고
    • Direct multiplexed measurement of gene expression with color-coded probe pairs
    • Geiss GK, Bumgarner RE, Birditt B, Dahl T, Dowidar N, et al. 2008. Direct multiplexed measurement of gene expression with color-coded probe pairs. Nat. Biotechnol. 26:317-325
    • (2008) Nat. Biotechnol. , vol.26 , pp. 317-325
    • Geiss, G.K.1    Bumgarner, R.E.2    Birditt, B.3    Dahl, T.4    Dowidar, N.5
  • 192
    • 37749047490 scopus 로고    scopus 로고
    • Sequence census methods for functional genomics
    • Wold B, Myers RM. 2008. Sequence census methods for functional genomics. Nat. Methods 5:19-21
    • (2008) Nat. Methods , vol.5 , pp. 19-21
    • Wold, B.1    Myers, R.M.2
  • 193
    • 47649124124 scopus 로고    scopus 로고
    • A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome
    • Sultan M, Schulz MH, Richard H, Magen A, Klingenhoff A, et al. 2008. A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome. Science 321:956-960
    • (2008) Science , vol.321 , pp. 956-960
    • Sultan, M.1    Schulz, M.H.2    Richard, H.3    Magen, A.4    Klingenhoff, A.5
  • 194
    • 33746324216 scopus 로고    scopus 로고
    • Chromatin modifications by methylation and ubiquitination: Implications in the regulation of gene expression
    • Shilatifard A. 2006. Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression. Annu. Rev. Biochem. 75:243-269
    • (2006) Annu. Rev. Biochem. , vol.75 , pp. 243-269
    • Shilatifard, A.1
  • 195
    • 28544440530 scopus 로고    scopus 로고
    • Autoantibodies make a U-turn: The toll hypothesis for autoantibody specificity
    • Martin DA, Elkon KB. 2005. Autoantibodies make a U-turn: the toll hypothesis for autoantibody specificity. J. Exp. Med. 202:1465-1469
    • (2005) J. Exp. Med. , vol.202 , pp. 1465-1469
    • Martin, D.A.1    Elkon, K.B.2
  • 196
    • 34247236200 scopus 로고    scopus 로고
    • Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE
    • Tian J, Avalos AM, Mao SY, Chen B, Senthil K, et al. 2007. Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE. Nat. Immunol. 8:487-496
    • (2007) Nat. Immunol. , vol.8 , pp. 487-496
    • Tian, J.1    Avalos, A.M.2    Mao, S.Y.3    Chen, B.4    Senthil, K.5
  • 197
    • 34948862264 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide
    • Lande R, Gregorio J, Facchinetti V, Chatterjee B, Wang YH, et al. 2007. Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide. Nature 449:564-569
    • (2007) Nature , vol.449 , pp. 564-569
    • Lande, R.1    Gregorio, J.2    Facchinetti, V.3    Chatterjee, B.4    Wang, Y.H.5
  • 198
    • 69549135324 scopus 로고    scopus 로고
    • Self-RNA-antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8
    • Ganguly D, Chamilos G, Lande R, Gregorio J, Meller S, et al. 2009. Self-RNA-antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8. J. Exp. Med. 206:1983-1994
    • (2009) J. Exp. Med. , vol.206 , pp. 1983-1994
    • Ganguly, D.1    Chamilos, G.2    Lande, R.3    Gregorio, J.4    Meller, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.