Roles of epithelial cell-derived periostin in TGF-β activation, collagen production, and collagen gel elasticity in asthma

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 32, 2010, Pages 14170-14175

  Sidhu, Sukhvinder S ^a   Yuan, Shaopeng ^a   Innes, Anh L ^a,b   Kerr, Sheena ^a   Woodruff, Prescott G ^a,b   Hou, Lydia ^b   Muller, Susan J ^c   Fahy, John V ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c University of California   (United States)

Author keywords

Airway fibrosis; Epithelial to mesenchymal transition; Fibroblasts; MMP 2; MMP 9

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; COLLAGEN FIBRIL; COLLAGEN GEL; COLLAGEN TYPE 1; GELATINASE A; GELATINASE B; INTEGRIN; INTERLEUKIN 13; RECOMBINANT PERIOSTIN; RECOMBINANT PROTEIN; TRANSCRIPTION FACTOR RUNX2; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; CELL ADHESION MOLECULE; MATRIX METALLOPROTEINASE; POSTN PROTEIN, HUMAN;

ARTICLE; ASTHMA; CELL FUNCTION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; ELASTICITY; ENZYME ACTIVATION; EPITHELIUM CELL; FIBROBLAST; FIBROSIS; GENE EXPRESSION; HUMAN; HUMAN CELL; IN SITU HYBRIDIZATION; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN SECRETION; SIGNAL TRANSDUCTION; STABLE TRANSFECTION; UPREGULATION; BIOSYNTHESIS; BRONCHUS; CELL CULTURE; CHEMISTRY; CYTOLOGY; GEL; METABOLISM; PATHOLOGY; PHYSIOLOGY; SECRETION;

ASTHMA; BRONCHI; CELL ADHESION MOLECULES; CELLS, CULTURED; COLLAGEN TYPE I; ELASTICITY; EPITHELIAL CELLS; GELS; HUMANS; MATRIX METALLOPROTEINASES; TRANSFORMING GROWTH FACTOR BETA;

EID: 77956289251     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1009426107     Document Type: Article

References (43)

1. Woodruff PG, et al. (2007) Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids. Proc Natl Acad Sci USA 104:15858-15863.
2. Litvin J, Zhu S, Norris R, Markwald R (2005) Periostin family of proteins: Therapeutic targets for heart disease. Anat Rec A Discov Mol Cell Evol Biol 287:1205-1212. (Pubitemid 43010431)
3. Kudo Y, Siriwardena BS, Hatano H, Ogawa I, Takata T (2007) Periostin: Novel diagnostic and therapeutic target for cancer. Histol Histopathol 22:1167-1174.
4. Dorn GW, 2nd (2007) Periostin and myocardial repair, regeneration, and recovery. N Engl J Med 357:1552-1554.
5. Borg TK, Markwald R (2007) Periostin: More than just an adhesion molecule. Circ Res 101:230-231.
6. Kii I, et al. (2006) Periostin is an extracellular matrix protein required for eruption of incisors in mice. Biochem Biophys Res Commun 342:766-772. (Pubitemid 43320464)
7. Kikuchi Y, et al. (2008) Periostin is expressed in pericryptal fibroblasts and cancer-associated fibroblasts in the colon. J Histochem Cytochem 56:753-764.
8. Butcher JT, Norris RA, Hoffman S, Mjaatvedt CH, Markwald RR (2007) Periostin promotes atrioventricular mesenchyme matrix invasion and remodeling mediated by integrin signaling through Rho/PI 3-kinase. Dev Biol 302:256-266. (Pubitemid 46099041)
9. Gillan L, et al. (2002) Periostin secreted by epithelial ovarian carcinoma is a ligand for alpha(V)beta(3) and alpha(V)beta(5) integrins and promotes cell motility. Cancer Res 62:5358-5364.
10. Norris RA, et al. (2007) Periostin regulates collagen fibrillogenesis and the biomechanical properties of connective tissues. J Cell Biochem 101:695-711.
11. Rios H, et al. (2005) Periostin null mice exhibit dwarfism, incisor enamel defects, and an early-onset periodontal disease-like phenotype. Mol Cell Biol 25:11131-11144.
12. Rios HF, et al. (2008) Periostin is essential for the integrity and function of the periodontal ligament during occlusal loading in mice. J Periodontol 79:1480-1490.
13. Fish JE, Peters SP (1999) Airway remodeling and persistent airway obstruction in asthma. J Allergy Clin Immunol 104:509-516. (Pubitemid 29451635)
14. Paré PD, Roberts CR, Bai TR, Wiggs BJ (1997) The functional consequences of airway remodeling in asthma. Monaldi Arch Chest Dis 52:589-596.
15. Pascual RM, Peters SP (2005) Airway remodeling contributes to the progressive loss of lung function in asthma: An overview. J Allergy Clin Immunol 116:477-486.
16. Berry M, et al. (2007) Pathological features and inhaled corticosteroid response of eosinophilic and non-eosinophilic asthma. Thorax 62:1043-1049.
17. Wenzel SE, et al. (1999) Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics. Am J Respir Crit Care Med 160:1001-1008.
18. Ward C, et al. (2001) Reduced airway distensibility, fixed airflow limitation, and airway wall remodeling in asthma. Am J Respir Crit Care Med 164:1718-1721.
19. Brown NJ, Salome CM, Berend N, Thorpe CW, King GG (2007) Airway distensibility in adults with asthma and healthy adults, measured by forced oscillation technique. Am J Respir Crit Care Med 176:129-137. (Pubitemid 47057848)
20. Brewster CEP, et al. (1990) Myofibroblasts and subepithelial fibrosis in bronchial asthma. Am J Respir Cell Mol Biol 3:507-511.
21. Evans MJ, et al. (2004) The remodelled tracheal basement membrane zone of infant rhesus monkeys after 6 months of recovery. Clin Exp Allergy 34:1131-1136.
22. Takayama G, et al. (2006) Periostin: A novel component of subepithelial fibrosis of bronchial asthma downstream of IL-4 and IL-13 signals. J Allergy Clin Immunol 118:98-104.
23. Blanchard C, et al. (2008) Periostin facilitates eosinophil tissue infiltration in allergic lung and esophageal responses. Mucosal Immunol 1:289-296.
24. Evans MJ, Van Winkle LS, Fanucchi MV, Plopper CG (1999) The attenuated fibroblast sheath of the respiratory tract epithelial-mesenchymal trophic unit. Am J Respir Cell Mol Biol 21:655-657.
25. Holgate ST (2007) Epithelium dysfunction in asthma. J Allergy Clin Immunol 120:1233-1244.
26. Knight D (2001) Epithelium-fibroblast interactions in response to airway inflammation. Immunol Cell Biol 79:160-164.
27. Araya J, et al. (2007) Squamous metaplasia amplifies pathologic epithelial-mesenchymal interactions in COPD patients. J Clin Invest 117:3551-3562.
28. Woodruff PG, et al. (2009) Th2-driven inflammation defines major sub-phenotypes of asthma. Am J Respir Crit Care Med 180:388-395.
29. Litvin J, et al. (2004) Expression and function of periostin-isoforms in bone. J Cell Biochem 92:1044-1061.
30. Sheppard D (2006) Transforming growth factor beta: A central modulator of pulmonary and airway inflammation and fibrosis. Proc Am Thorac Soc 3:413-417.
31. Pittet JF, et al. (2001) TGF-beta is a critical mediator of acute lung injury. J Clin Invest 107:1537-1544.
32. Doerner AM, Zuraw BL (2009) TGF-beta1 induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells is enhanced by IL-1beta but not abrogated by corticosteroids. Respir Res 10:100.
33. Annes JP, Munger JS, Rifkin DB (2003) Making sense of latent TGFbeta activation. J Cell Sci 116:217-224.
34. Wu L, Derynck R (2009) Essential role of TGF-beta signaling in glucose-induced cell hypertrophy. Dev Cell 17:35-48.
35. Barnes HA, Hutton JF, Walters K (1989) An Introduction to Rheology (Elsevier, Amsterdam).
36. Innes AL, et al. (2009) Ex vivo sputum analysis reveals impairment of protease-dependent mucus degradation by plasma proteins in acute asthma. Am J Respir Crit Care Med 180:203-210.
37. Woodruff PG, Fahy JV (2002) Airway remodeling in asthma. Semin Respir Crit Care Med 23:361-367.
38. Kenyon NJ, Ward RW, McGrew G, Last JA (2003) TGF-beta1 causes airway fibrosis and increased collagen I and III mRNA in mice. Thorax 58:772-777. (Pubitemid 37094053)
39. Sagara H, et al. (2002) Activation of TGF-beta/Smad2 signaling is associated with airway remodeling in asthma. J Allergy Clin Immunol 110:249-254.
40. Levental KR, et al. (2009) Matrix crosslinking forces tumor progression by enhancing integrin signaling. Cell 139:891-906.
41. Bao S, et al. (2004) Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway. Cancer Cell 5:329-339.
42. Finkbeiner WE (1997) Respiratory cell culture. The Lung: Scientific Foundations, ed Crystal RG (Lipincott-Raven, Philadelphia), pp 415-433.
43. Abe M, et al. (1994) An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct. Anal Biochem 216:276-284.