-
1
-
-
33745410626
-
Mitochondrial disease
-
DOI 10.1016/S0140-6736(06)68970-8, PII S0140673606689708
-
Schapira A. H., Mitochondrial disease Lancet 2006 368 9529 70 82 (Pubitemid 43947206)
-
(2006)
Lancet
, vol.368
, Issue.9529
, pp. 70-82
-
-
Schapira, A.H.1
-
2
-
-
0034700807
-
Mitochondrial respiratory chain disorders I: Mitochondrial DNA defects
-
DOI 10.1016/S0140-6736(99)05225-3
-
Leonard J. V., Schapira A. H. V., Mitochondrial respiratory chain disordersI: mitochondrial DNA defects Lancet 2000 355 9200 299 304 (Pubitemid 30068529)
-
(2000)
Lancet
, vol.355
, Issue.9200
, pp. 299-304
-
-
Leonard, J.V.1
Schapira, A.H.V.2
-
3
-
-
0034728096
-
Mitochondrial respiratory chain disordersII: Neurodegenerative disorders and nuclear gene defects
-
Leonard J. V., Schapira A. H. V., Mitochondrial respiratory chain disordersII: neurodegenerative disorders and nuclear gene defects Lancet 2000 355 9201 389 394
-
(2000)
Lancet
, vol.355
, Issue.9201
, pp. 389-394
-
-
Leonard, J.V.1
Schapira, A.H.V.2
-
4
-
-
0024390719
-
Mitochondrial complex I deficiency in Parkinson's disease
-
Schapira A. H. V., Cooper J. M., Dexter D., Jenner P., Clark J. B., Marsden C. D., Mitochondrial complex I deficiency in Parkinson's disease Lancet 1989 1 8649 1269 (Pubitemid 19140359)
-
(1989)
Lancet
, vol.1
, Issue.8649
, pp. 1269
-
-
Schapira, A.H.V.1
Cooper, J.M.2
Dexter, D.3
Jenner, P.4
Clark, J.B.5
Marsden, C.D.6
-
5
-
-
0028274216
-
Evidence for mitochondrial dysfunction in Parkinson's disease - A critical appraisal
-
Schapira A. H. V., Evidence for mitochondrial dysfunction in Parkinson's diseasea critical appraisal Movement Disorders 1994 9 2 125 138 (Pubitemid 24092327)
-
(1994)
Movement Disorders
, vol.9
, Issue.2
, pp. 125-138
-
-
Schapira, A.H.V.1
-
6
-
-
0025254401
-
Mitochondrial Complex i deficiency in Parkinson's disease
-
Schapira A. H. V., Cooper J. M., Dexter D., Clark J. B., Jenner P., Marsden C. D., Mitochondrial Complex I deficiency in Parkinson's disease Journal of Neurochemistry 1990 54 3 823 827
-
(1990)
Journal of Neurochemistry
, vol.54
, Issue.3
, pp. 823-827
-
-
Schapira, A.H.V.1
Cooper, J.M.2
Dexter, D.3
Clark, J.B.4
Jenner, P.5
Marsden, C.D.6
-
7
-
-
0025640845
-
1 reductase (complex I) deficiency in parkinson's disease
-
Schapira A. H. V., Mann V. M., Cooper J. M., Dexter D., Daniel S. E., Jenner P., Clark J. B., Marsden C. D., Anatomic and disease specificity of NADH CoQ reductase (complex I) deficiency in Parkinson's disease Journal of Neurochemistry 1990 55 6 2142 2145 (Pubitemid 120021853)
-
(1990)
Journal of Neurochemistry
, vol.55
, Issue.6
, pp. 2142-2145
-
-
Schapira, A.H.V.1
Mann, V.M.2
Cooper, J.M.3
Dexter, D.4
Daniel, S.E.5
Jenner, P.6
Clark, J.B.7
Marsden, C.D.8
-
8
-
-
41749104745
-
Complex I deficiency in Parkinson's disease frontal cortex
-
DOI 10.1016/j.brainres.2007.10.061, PII S0006899307025814
-
Parker W. D. Jr., Parks J. K., Swerdlow R. H., Complex I deficiency in Parkinson's disease frontal cortex Brain Research 2008 1189 1 215 218 (Pubitemid 351842538)
-
(2008)
Brain Research
, vol.1189
, Issue.1
, pp. 215-218
-
-
Parker Jr., W.D.1
Parks, J.K.2
Swerdlow, R.H.3
-
9
-
-
0026704075
-
Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases affecting the basal ganglia
-
Dexter D. T., Jenner P., Schapira A. H.V., Marsden C. D., Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases affecting the basal ganglia Annals of Neurology 1992 32, supplement S94 S100
-
(1992)
Annals of Neurology
, vol.32
-
-
Dexter, D.T.1
Jenner, P.2
Schapira, A.H.V.3
Marsden, C.D.4
-
10
-
-
0027995435
-
Complex I, iron, and ferritin in Parkinson's disease substantia nigra
-
DOI 10.1002/ana.410360612
-
Mann V. M., Cooper J. M., Daniel S. E., Srai K., Jenner P., Marsden C. D., Schapira A. H. V., Complex I, iron, and ferritin in Parkinson's disease substantia nigra Annals of Neurology 1994 36 6 876 881 (Pubitemid 24370927)
-
(1994)
Annals of Neurology
, vol.36
, Issue.6
, pp. 876-881
-
-
Mann, V.M.1
Cooper, J.M.2
Daniel, S.E.3
Srai, K.4
Jenner, P.5
Marsden, C.D.6
Schapira, A.H.V.7
-
12
-
-
0029741621
-
Oxidative stress and Parkinson's disease
-
Owen A. D., Schapira A. H. V., Jenner P., Marsden C. D., Oxidative stress and Parkinson's disease Annals of the New York Academy of Sciences 1996 786 217 223 (Pubitemid 26273166)
-
(1996)
Annals of the New York Academy of Sciences
, vol.786
, pp. 217-223
-
-
Owen, A.D.1
Schapira, A.H.V.2
Jenner, P.3
Marsden, C.D.4
-
13
-
-
0032507983
-
Mitochondrial function, GSH and iron in neurodegeneration and Lewy body diseases
-
DOI 10.1016/S0022-510X(98)00095-1, PII S0022510X98000951
-
Gu M., Owen A. D., Toffa S. E. K., Cooper J. M., Dexter D. T., Jenner P., Marsden C. D., Schapira A. H. V., Mitochondrial function, GSH and iron in neurodegeneration and Lewy body diseases Journal of the Neurological Sciences 1998 158 1 24 29 (Pubitemid 28277530)
-
(1998)
Journal of the Neurological Sciences
, vol.158
, Issue.1
, pp. 24-29
-
-
Gu, M.1
Owen, A.D.2
Toffa, S.E.K.3
Cooper, J.M.4
Dexter, D.T.5
Jenner, P.6
Marsden, C.D.7
Schapira, A.H.V.8
-
14
-
-
0027496238
-
A radical hypothesis for neurodegeneration
-
DOI 10.1016/0166-2236(93)90070-3
-
Olanow C. W., A radical hypothesis for neurodegeneration Trends in Neurosciences 1993 16 11 439 444 (Pubitemid 23313517)
-
(1993)
Trends in Neurosciences
, vol.16
, Issue.11
, pp. 439-444
-
-
Olanow, C.W.1
-
15
-
-
0029029469
-
Mitochondrial DNA (mtDNA) diseases: Correlation of genotype to phenotype
-
Morgan-Hughes J. A., Sweeney M. G., Cooper J. M., Hammans S. R., Brockington M., Schapira A. H. V., Harding A. E., Clark J. B., Mitochondrial DNA (mtDNA) diseases: correlation of genotype to phenotype Biochimica et Biophysica Acta 1995 1271 1 135 140
-
(1995)
Biochimica et Biophysica Acta
, vol.1271
, Issue.1
, pp. 135-140
-
-
Morgan-Hughes, J.A.1
Sweeney, M.G.2
Cooper, J.M.3
Hammans, S.R.4
Brockington, M.5
Schapira, A.H.V.6
Harding, A.E.7
Clark, J.B.8
-
16
-
-
0033768121
-
A novel mitochondrial 12SrRNA point mutation in parkinsonism, deafness, and neuropathy
-
Thyagarajan D., Bressman S., Bruno C., Przedborski S., Shanske S., Lynch T., Fahn S., Dimauro S., A novel mitochondrial 12SrRNA point mutation in parkinsonism, deafness, and neuropathy Annals of Neurology 2000 48 5 730 736
-
(2000)
Annals of Neurology
, vol.48
, Issue.5
, pp. 730-736
-
-
Thyagarajan, D.1
Bressman, S.2
Bruno, C.3
Przedborski, S.4
Shanske, S.5
Lynch, T.6
Fahn, S.7
Dimauro, S.8
-
17
-
-
0023919376
-
Molecular defects of NADH-ubiquinone oxidoreductase (Complex I) in mitochondrial diseases
-
Morgan-Hughes J. A., Schapira A. H. V., Cooper J. M., Clark J. B., Molecular defects of NADH-ubiquinone oxidoreductase (Complex I) in mitochondrial diseases Journal of Bioenergetics and Biomembranes 1988 20 3 365 382
-
(1988)
Journal of Bioenergetics and Biomembranes
, vol.20
, Issue.3
, pp. 365-382
-
-
Morgan-Hughes, J.A.1
Schapira, A.H.V.2
Cooper, J.M.3
Clark, J.B.4
-
18
-
-
0023836601
-
Molecular basis of mitochondrial myopathies: Polypeptide analysis in complex-I deficiency
-
Schapira A. H. V., Cooper J. M., Morgan-Hughes J. A., Patel S. D., Cleeter M. J. W., Ragan C. I., Clark J. B., Molecular basis of mitochondrial myopathies: polypeptide analysis in complex-I deficiency Lancet 1988 1 8584 500 503 (Pubitemid 18059684)
-
(1988)
Lancet
, vol.1
, Issue.8584
, pp. 500-503
-
-
Schapira, A.H.V.1
Cooper, J.M.2
Morgan-Hughes, J.A.3
Patel, S.D.4
Cleeter, M.J.W.5
Ragan, C.I.6
Clark, J.B.7
-
19
-
-
0032231458
-
Cytochrome c oxidase deficiency associated with the first stop-codon point mutation in human mtDNA
-
DOI 10.1086/301910
-
Hanna M. G., Nelson I. P., Rahman S., Lane R. J. M., Land J., Heales S., Cooper M. J., Schapira A. H. V., Morgan-Hughes J. A., Wood N. W., Cytochrome c oxidase deficiency associated with the first stop-codon point mutation in human mtDNA American Journal of Human Genetics 1998 63 1 29 36 (Pubitemid 30428314)
-
(1998)
American Journal of Human Genetics
, vol.63
, Issue.1
, pp. 29-36
-
-
Hanna, M.G.1
Nelson, I.P.2
Rahman, S.3
Lane, R.J.M.4
Land, J.5
Heales, S.6
Cooper, M.J.7
Schapira, A.H.V.8
Morgan-Hughes, J.A.9
Wood, N.W.10
-
20
-
-
0001411977
-
A missense mutation of cytochrome oxidase subunit II causes defective assembly and myopathy
-
DOI 10.1086/302590
-
Rahman S., Taanman J. W., Cooper J. M., Nelson I., Hargreaves I., Meunier B., Hanna M. G., Garca J. J., Capaldi R. A., Lake B. D., Leonard J. V., Schapira A. H. V., A missense mutation of cytochrome oxidase subunit II causes defective assembly and myopathy American Journal of Human Genetics 1999 65 4 1030 1039 (Pubitemid 30462959)
-
(1999)
American Journal of Human Genetics
, vol.65
, Issue.4
, pp. 1030-1039
-
-
Rahman, S.1
Taanman, J.-W.2
Cooper, J.M.3
Nelson, I.4
Hargreaves, I.5
Meunier, B.6
Hanna, M.G.7
Garcia, J.J.8
Capaldi, R.A.9
Lake, B.D.10
Leonard, J.V.11
Schapira, A.H.V.12
-
21
-
-
3543017697
-
A novel polymerase γ mutation in a family with ophthalmoplegia, neuropathy, and parkinsonism
-
DOI 10.1001/archneur.61.11.1777
-
Mancuso M., Filosto M., Oh S. J., DiMauro S., A novel polymerase mutation in a family with ophthalmoplegia, neuropathy, and parkinsonism Archives of Neurology 2004 61 11 1777 1779 (Pubitemid 39463436)
-
(2004)
Archives of Neurology
, vol.61
, Issue.11
, pp. 1777-1779
-
-
Mancuso, M.1
Filosto, M.2
Oh, S.J.3
DiMauro, S.4
-
22
-
-
33646358693
-
Early-onset familial parkinsonism due to POLG mutations
-
DOI 10.1002/ana.20831
-
Davidzon G., Greene P., Mancuso M., Klos K. J., Ahlskog J. E., Hirano M., DiMauro S., Early-onset familial parkinsonism due to POLG mutations Annals of Neurology 2006 59 5 859 862 (Pubitemid 43673164)
-
(2006)
Annals of Neurology
, vol.59
, Issue.5
, pp. 859-862
-
-
Davidzon, G.1
Greene, P.2
Mancuso, M.3
Klos, K.J.4
Ahlskog, J.E.5
Hirano, M.6
DiMauro, S.7
-
23
-
-
4544273256
-
Parkinsonism, premature menopause, and mitochondrial DNA polymerase γ mutations: Clinical and molecular genetic study
-
DOI 10.1016/S0140-6736(04)16983-3, PII S0140673604169833
-
Luoma P., Melberg A., Rinne J. O., Kaukonen J. A., Nupponen N. N., Chalmers R. M., Oldfors P. A., Rautakorpi I., Peltonen P. L., Majamaa P. K., Somer H., Suomalainen A., Parkinsonism, premature menopause, and mitochondrial DNA polymerase mutations: clinical and molecular genetic study Lancet 2004 364 9437 875 882 (Pubitemid 39221065)
-
(2004)
Lancet
, vol.364
, Issue.9437
, pp. 875-882
-
-
Luoma, P.1
Melberg, A.2
Rinne, J.O.3
Kaukonen, J.A.4
Nupponen, N.N.5
Chalmers, R.M.6
Oldfors, P.A.7
Rautakorpi, I.8
Peltonen, P.L.9
Majamaa, P.K.10
Somer, H.11
Suomalainen, A.12
-
24
-
-
0031971261
-
Liver failure associated with mitochondrial DNA depletion
-
DOI 10.1016/S0168-8278(98)80278-X
-
Morris A. A. M., Taanman J. W., Blake J., Mark Cooper J., Lake B. D., Malone M., Love S., Clayton P. T., Leonard J. V., Schapira A. H. V., Liver failure associated with mitochondrial DNA depletion Journal of Hepatology 1998 28 4 556 563 (Pubitemid 28167992)
-
(1998)
Journal of Hepatology
, vol.28
, Issue.4
, pp. 556-563
-
-
Morris, A.A.M.1
Taanman, J.-W.2
Blake, J.3
Mark Cooper, J.4
Lake, B.D.5
Malone, M.6
Love, S.7
Clayton, P.T.8
Leonard, J.V.9
Schapira, A.H.V.10
-
25
-
-
59749083796
-
Analysis of mutant DNA polymerase in patients with mitochondrial DNA depletion
-
Taanman J. W., Rahman S., Pagnamenta A. T., Morris A. A. M., Bitner-Glindzicz M., Wolf N. I., Leonard J. V., Clayton P. T., Schapira A. H. V., Analysis of mutant DNA polymerase in patients with mitochondrial DNA depletion Human Mutation 2009 30 2 248 254
-
(2009)
Human Mutation
, vol.30
, Issue.2
, pp. 248-254
-
-
Taanman, J.W.1
Rahman, S.2
Pagnamenta, A.T.3
Morris, A.A.M.4
Bitner-Glindzicz, M.5
Wolf, N.I.6
Leonard, J.V.7
Clayton, P.T.8
Schapira, A.H.V.9
-
26
-
-
13444270783
-
Analysis of the trinucleotide CAG repeat from the DNA polymerase γ gene (POLG) in patients with Parkinson's disease
-
DOI 10.1016/j.neulet.2004.11.023
-
Taanman J. W., Schapira A. H. V., Analysis of the trinucleotide CAG repeat from the DNA polymerase gene (POLG) in patients with Parkinson's disease Neuroscience Letters 2005 376 1 56 59 (Pubitemid 40202937)
-
(2005)
Neuroscience Letters
, vol.376
, Issue.1
, pp. 56-59
-
-
Taanman, J.-W.1
Schapira, A.H.V.2
-
27
-
-
34247122280
-
Mutation of the linker region of the polymerase γ-1 (POLG1) gene associated with progressive external ophthalmoplegia and parkinsonism
-
Hudson G., Schaefer A. M., Taylor R. W., Tiangyou W., Gibson A., Venables G., Griffiths P., Burn D. J., Turnbull D. M., Chinnery P. F., Mutation of the linker region of the polymerase -1 (POLG1) gene associated with progressive external ophthalmoplegia and parkinsonism Archives of Neurology 2007 64 4 553 557 (Pubitemid 46588345)
-
(2007)
Archives of Neurology
, vol.64
, Issue.4
, pp. 553-557
-
-
Hudson, G.1
Schaefer, A.M.2
Taylor, R.W.3
Tiangyou, W.4
Gibson, A.5
Venables, G.6
Griffiths, P.7
Burn, D.J.8
Turnbull, D.M.9
Chinnery, P.F.10
-
28
-
-
0026469073
-
Analyses of mitochondrial respiratory chain function and mitochondrial DNA deletion in human skeletal muscle: Effect of ageing
-
Cooper J. M., Mann V. M., Schapira A. H. V., Analyses of mitochondrial respiratory chain function and mitochondrial DNA deletion in human skeletal muscle: effect of ageing Journal of the Neurological Sciences 1992 113 1 91 98
-
(1992)
Journal of the Neurological Sciences
, vol.113
, Issue.1
, pp. 91-98
-
-
Cooper, J.M.1
Mann, V.M.2
Schapira, A.H.V.3
-
29
-
-
0026548217
-
Quantitation of a mitochondrial DNA deletion in Parkinson's disease
-
Mann V. M., Cooper J. M., Schapira A. H. V., Quantitation of a mitochondrial DNA deletion in Parkinson's disease FEBS Letters 1992 299 3 218 222
-
(1992)
FEBS Letters
, vol.299
, Issue.3
, pp. 218-222
-
-
Mann, V.M.1
Cooper, J.M.2
Schapira, A.H.V.3
-
30
-
-
33646351299
-
Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons
-
Kraytsberg Y., Kudryavtseva E., McKee A. C., Geula C., Kowall N. W., Khrapko K., Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons Nature Genetics 2006 38 5 518 520
-
(2006)
Nature Genetics
, vol.38
, Issue.5
, pp. 518-520
-
-
Kraytsberg, Y.1
Kudryavtseva, E.2
McKee, A.C.3
Geula, C.4
Kowall, N.W.5
Khrapko, K.6
-
31
-
-
33646375711
-
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
-
Bender A., Krishnan K. J., Morris C. M., Taylor G. A., Reeve A. K., Perry R. H., Jaros E., Hersheson J. S., Betts J., Klopstock T., Taylor R. W., Turnbull D. M., High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease Nature Genetics 2006 38 5 515 517
-
(2006)
Nature Genetics
, vol.38
, Issue.5
, pp. 515-517
-
-
Bender, A.1
Krishnan, K.J.2
Morris, C.M.3
Taylor, G.A.4
Reeve, A.K.5
Perry, R.H.6
Jaros, E.7
Hersheson, J.S.8
Betts, J.9
Klopstock, T.10
Taylor, R.W.11
Turnbull, D.M.12
-
32
-
-
34347359673
-
Rejuvenation protects neurons in mouse models of Parkinson's disease
-
DOI 10.1038/nature05865, PII NATURE05865
-
Chan C. S., Guzman J. N., Ilijic E., Mercer J. N., Rick C., Tkatch T., Meredith G. E., Surmeier D. J., Rejuvenation protects neurons in mouse models of Parkinson's disease Nature 2007 447 7148 1081 1086 (Pubitemid 47014425)
-
(2007)
Nature
, vol.447
, Issue.7148
, pp. 1081-1086
-
-
Chan, C.S.1
Guzman, J.N.2
Ilijic, E.3
Mercer, J.N.4
Rick, C.5
Tkatch, T.6
Meredith, G.E.7
Surmeier, D.J.8
-
33
-
-
77549084979
-
Calcium, cellular aging, and selective neuronal vulnerability in Parkinson's disease
-
Surmeier D. J., Guzman J. N., Sanchez-Padilla J., Calcium, cellular aging, and selective neuronal vulnerability in Parkinson's disease Cell Calcium 2010 47 2 175 182
-
(2010)
Cell Calcium
, vol.47
, Issue.2
, pp. 175-182
-
-
Surmeier, D.J.1
Guzman, J.N.2
Sanchez-Padilla, J.3
-
34
-
-
0034965086
-
Biochemical analysis of cybrids expressing mitochondrial DNA from Contursi kindred Parkinson's subjects
-
DOI 10.1006/exnr.2001.7674
-
Swerdlow R. H., Parks J. K., Cassarino D. S., Binder D. R., Bennett J. P., Di Iorio G., Golbe L. I., Parker W. D., Biochemical analysis of cybrids expressing mitochondrial DNA from Contursi kindred Parkinson's subjects Experimental Neurology 2001 169 2 479 485 (Pubitemid 32536740)
-
(2001)
Experimental Neurology
, vol.169
, Issue.2
, pp. 479-485
-
-
Swerdlow, R.H.1
Parks, J.K.2
Cassarino, D.S.3
Binder, D.R.4
Bennett Jr., J.P.5
Di Iorio, G.6
Golbe, L.I.7
Parker Jr. W.Davis8
-
35
-
-
57849101997
-
Relationships among molecular genetic and respiratory properties of Parkinson's disease cybrid cells show similarities to Parkinson's brain tissues
-
Borland M. K., Mohanakumar K. P., Rubinstein J. D., Keeney P. M., Xie J., Capaldi R., Dunham L. D., Trimmer P. A., Bennett J. P., Relationships among molecular genetic and respiratory properties of Parkinson's disease cybrid cells show similarities to Parkinson's brain tissues Biochimica et Biophysica Acta 2009 1792 1 68 74
-
(2009)
Biochimica et Biophysica Acta
, vol.1792
, Issue.1
, pp. 68-74
-
-
Borland, M.K.1
Mohanakumar, K.P.2
Rubinstein, J.D.3
Keeney, P.M.4
Xie, J.5
Capaldi, R.6
Dunham, L.D.7
Trimmer, P.A.8
Bennett, J.P.9
-
36
-
-
0034102780
-
Abnormal mitochondrial morphology in sporadic Parkinson's and Alzheimer's disease cybrid cell lines
-
DOI 10.1006/exnr.2000.7333
-
Trimmer P. A., Swerdlow R. H., Parks J. K., Keeney P., Bennett J. P., Miller S. W., Davis R. E., Parker W. D., Abnormal mitochondrial morphology in sporadic Parkinson's and Alzheimer's disease cybrid cell lines Experimental Neurology 2000 162 1 37 50 (Pubitemid 30170099)
-
(2000)
Experimental Neurology
, vol.162
, Issue.1
, pp. 37-50
-
-
Trimmer, P.A.1
Swerdlow, R.H.2
Parks, J.K.3
Keeney, P.4
Bennett Jr., J.P.5
Miller, S.W.6
Davis, R.E.7
Parker Jr., W.D.8
-
37
-
-
0031859395
-
Mitochondrial DNA transmission of the mitochondrial defect in Parkinson's disease
-
DOI 10.1002/ana.410440207
-
Gu M., Cooper J. M., Taanman J. W., Schapira A. H. V., Mitochondrial DNA transmission of the mitochondrial defect in Parkinson's disease Annals of Neurology 1998 44 2 177 186 (Pubitemid 28374105)
-
(1998)
Annals of Neurology
, vol.44
, Issue.2
, pp. 177-186
-
-
Gu, M.1
Cooper, J.M.2
Taanman, J.W.3
Schapira, A.H.V.4
-
38
-
-
2442668926
-
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
-
DOI 10.1126/science.1096284
-
Valente E. M., Abou-Sleiman P. M., Caputo V., Muqit M. M. K., Harvey K., Gispert S., Ali Z., Del Turco D., Bentivoglio A. R., Healy D. G., Albanese A., Nussbaum R., Gonzlez-Maldonado R., Deller T., Salvi S., Cortelli P., Gilks W. P., Latchman D. S., Harvey R. J., Dallapiccola B., Auburger G., Wood N. W., Hereditary early-onset Parkinson's disease caused by mutations in PINK1 Science 2004 304 5674 1158 1160 (Pubitemid 38661852)
-
(2004)
Science
, vol.304
, Issue.5674
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
Muqit, M.M.K.4
Harvey, K.5
Gispert, S.6
Ali, Z.7
Del Turco, D.8
Bentivoglio, A.R.9
Healy, D.G.10
Albanese, A.11
Nussbaum, R.12
Gonzalez-Maldonado, R.13
Deller, T.14
Salvi, S.15
Cortelli, P.16
Gilks, W.P.17
Latchman, D.S.18
Harvey, R.J.19
Dallapiccola, B.20
Auburger, G.21
Wood, N.W.22
more..
-
40
-
-
61649088435
-
PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death
-
Gandhi S., Wood-Kaczmar A., Yao Z., Plun-Favreau H., Deas E., Klupsch K., Downward J., Latchman D. S., Tabrizi S. J., Wood N. W., Duchen M. R., Abramov A. Y., PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death Molecular Cell 2009 33 5 627 638
-
(2009)
Molecular Cell
, vol.33
, Issue.5
, pp. 627-638
-
-
Gandhi, S.1
Wood-Kaczmar, A.2
Yao, Z.3
Plun-Favreau, H.4
Deas, E.5
Klupsch, K.6
Downward, J.7
Latchman, D.S.8
Tabrizi, S.J.9
Wood, N.W.10
Duchen, M.R.11
Abramov, A.Y.12
-
41
-
-
62749113469
-
Silencing of PINK1 expression affects mitochondrial DNA and oxidative phosphorylation in DOPAMINERGIC cells
-
article e4756
-
Gegg M. E., Cooper J. M., Schapira A. H. V., Taanman J. W., Silencing of PINK1 expression affects mitochondrial DNA and oxidative phosphorylation in DOPAMINERGIC cells PLoS ONE 2009 4 3, article e4756
-
(2009)
PLoS ONE
, vol.4
, Issue.3
-
-
Gegg, M.E.1
Cooper, J.M.2
Schapira, A.H.V.3
Taanman, J.W.4
-
42
-
-
33846288002
-
Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6
-
DOI 10.1016/j.nbd.2006.10.007, PII S0969996106002580
-
Hoepken H. H., Gispert S., Morales B., Wingerter O., Del Turco D., Mlsch A., Nussbaum R. L., Mller K., Drse S., Brandt U., Deller T., Wirth B., Kudin A. P., Kunz W. S., Auburger G., Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6 Neurobiology of Disease 2007 25 2 401 411 (Pubitemid 46124020)
-
(2007)
Neurobiology of Disease
, vol.25
, Issue.2
, pp. 401-411
-
-
Hoepken, H.-H.1
Gispert, S.2
Morales, B.3
Wingerter, O.4
Del Turco, D.5
Mulsch, A.6
Nussbaum, R.L.7
Muller, K.8
Drose, S.9
Brandt, U.10
Deller, T.11
Wirth, B.12
Kudin, A.P.13
Kunz, W.S.14
Auburger, G.15
-
43
-
-
56349137588
-
Mitochondrial respiratory dysfunction in familiar Parkinsonism associated with PINK1 mutation
-
Piccoli C., Sardanelli A., Scrima R., Ripoli M., Quarato G., D'Aprile A., Bellomo F., Scacco S., De Michele G., Filla A., Iuso A., Boffoli D., Capitanio N., Papa S., Mitochondrial respiratory dysfunction in familiar Parkinsonism associated with PINK1 mutation Neurochemical Research 2008 33 12 2565 2574
-
(2008)
Neurochemical Research
, vol.33
, Issue.12
, pp. 2565-2574
-
-
Piccoli, C.1
Sardanelli, A.2
Scrima, R.3
Ripoli, M.4
Quarato, G.5
D'Aprile, A.6
Bellomo, F.7
Scacco, S.8
De Michele, G.9
Filla, A.10
Iuso, A.11
Boffoli, D.12
Capitanio, N.13
Papa, S.14
-
44
-
-
68549136513
-
Differential effects of PINK1 nonsense and missense mutations on mitochondrial function and morphology
-
Grnewald A., Gegg M. E., Taanman J. W., King R. H., Kock N., Klein C., Schapira A. H. V., Differential effects of PINK1 nonsense and missense mutations on mitochondrial function and morphology Experimental Neurology 2009 219 1 266 273
-
(2009)
Experimental Neurology
, vol.219
, Issue.1
, pp. 266-273
-
-
Grnewald, A.1
Gegg, M.E.2
Taanman, J.W.3
King, R.H.4
Kock, N.5
Klein, C.6
Schapira, A.H.V.7
-
45
-
-
66749163493
-
Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration
-
article e5777
-
Gispert S., Ricciardi F., Kurz A., Azizov M., Hoepken H. H., Becker D., Voos W., Leuner K., Mller W. E., Kudin A. P., Kunz W. S., Zimmerman A., Roeper J., Wenzel D., Jendrach M., Garca-Arencbia M., Fernndez-Ruiz J., Huber L., Rohrer H., Barrera M., Reichert A. S., Rb U., Chen A., Nussbaum R. L., Auburger G., Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration PLoS ONE 2009 4 6, article e5777
-
(2009)
PLoS ONE
, vol.4
, Issue.6
-
-
Gispert, S.1
Ricciardi, F.2
Kurz, A.3
Azizov, M.4
Hoepken, H.H.5
Becker, D.6
Voos, W.7
Leuner, K.8
Mller, W.E.9
Kudin, A.P.10
Kunz, W.S.11
Zimmerman, A.12
Roeper, J.13
Wenzel, D.14
Jendrach, M.15
Garca-Arencbia, M.16
Fernndez-Ruiz, J.17
Huber, L.18
Rohrer, H.19
Barrera, M.20
Reichert, A.S.21
Rb, U.22
Chen, A.23
Nussbaum, R.L.24
Auburger, G.25
more..
-
46
-
-
4444274910
-
PINK1 mutations are associated with sporadic early-onset Parkinsonism
-
DOI 10.1002/ana.20256
-
Valente E. M., Salvi S., Ialongo T., Marongiu R., Elia A. E., Caputo V., Romito L., Albanese A., Dallapiccola B., Bentivoglio A. R., PINK1 mutations are associated with sporadic early-onset Parkinsonism Annals of Neurology 2004 56 3 336 341 (Pubitemid 39166552)
-
(2004)
Annals of Neurology
, vol.56
, Issue.3
, pp. 336-341
-
-
Valente, E.M.1
Salvi, S.2
Ialongo, T.3
Marongiu, R.4
Elia, A.E.5
Caputo, V.6
Romito, L.7
Albanese, A.8
Dallapiccola, B.9
Bentivoglio, A.R.10
-
47
-
-
4444237208
-
Novel PINK1 mutations in early-onset parkinsonism
-
DOI 10.1002/ana.20251
-
Hatano Y., Li Y., Sato K., Asakawa S., Yamamura Y., Tomiyama H., Yoshino H., Asahina M., Kobayashi S., Hassin-Baer S., Lu C. S., Ng A. R., Rosales R. L., Shimizu N., Toda T., Mizuno Y., Hattori N., Novel PINK1 mutations in early-onset parkinsonism Annals of Neurology 2004 56 3 424 427 (Pubitemid 39166562)
-
(2004)
Annals of Neurology
, vol.56
, Issue.3
, pp. 424-427
-
-
Hatano, Y.1
Li, Y.2
Sato, K.3
Asakawa, S.4
Yamamura, Y.5
Tomiyama, H.6
Yoshino, H.7
Asahina, M.8
Kobayashi, S.9
Hassin-Baer, S.10
Lu, C.-S.11
Ng, A.R.12
Rosales, R.L.13
Shimizu, N.14
Toda, T.15
Mizuno, Y.16
Hattori, N.17
-
48
-
-
4444269012
-
Homozygous PINK1 C-terminus mutation causing early-onset parkinsonism
-
DOI 10.1002/ana.20247
-
Roh C. F., Montagna P., Breedveld G., Cortelli P., Oostra B. A., Bonifati V., Homozygous PINK1 C-terminus mutation causing early-onset parkinsonism Annals of Neurology 2004 56 3 427 431 (Pubitemid 39166563)
-
(2004)
Annals of Neurology
, vol.56
, Issue.3
, pp. 427-431
-
-
Rohe, C.F.1
Montagna, P.2
Breedveld, G.3
Cortelli, P.4
Oostra, B.A.5
Bonifati, V.6
-
49
-
-
0028853625
-
Mammalian cytochrome-c oxidase: Characterization of enzyme and immunological detection of subunits in tissue extracts and whole cells
-
Capaldi R. A., Marusich M. F., Taanman J. W., Mammalian cytochrome-c oxidase: characterization of enzyme and immunological detection of subunits in tissue extracts and whole cells Methods in Enzymology 1995 260 117 132
-
(1995)
Methods in Enzymology
, vol.260
, pp. 117-132
-
-
Capaldi, R.A.1
Marusich, M.F.2
Taanman, J.W.3
-
50
-
-
0029984584
-
Subunit specific monoclonal antibodies show different steady-state levels of various cytochrome-c oxidase subunits in chronic progressive external ophthalmoplegia
-
DOI 10.1016/0925-4439(95)00127-1
-
Taanman J. W., Burton M. D., Marusich M. F., Kennaway N. G., Capaldi R. A., Subunit specific monoclonal antibodies show different steady-state levels of various cytochrome-c oxidase subunits in chronic progressive external ophthalmoplegia Biochimica et Biophysica Acta 1996 1315 3 199 207 (Pubitemid 26128328)
-
(1996)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1315
, Issue.3
, pp. 199-207
-
-
Taanman, J.-W.1
Burton, M.D.2
Marusich, M.F.3
Kennaway, N.G.4
Capaldi, R.A.5
-
51
-
-
0038034950
-
Analysis of steady-state protein phosphorylation in mitochondria using a novel fluorescent phosphosensor dye
-
DOI 10.1074/jbc.C300189200
-
Schulenberg B., Aggeler R., Beechem J. M., Capaldi R. A., Patton W. F., Analysis of steady-state protein phosphorylation in mitochondria using a novel fluorescent phosphosensor dye Journal of Biological Chemistry 2003 278 29 27251 27255 (Pubitemid 36876882)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.29
, pp. 27251-27255
-
-
Schulenberg, B.1
Aggeler, R.2
Beechem, J.M.3
Capaldi, R.A.4
Patton, W.F.5
-
52
-
-
2942726285
-
The phosphorylation of subunits of complex i from bovine heart mitochondria
-
DOI 10.1074/jbc.M402710200
-
Chen R., Fearnley I. M., Peak-Chew S. Y., Walker J. E., The phosphorylation of subunits of complex i from bovine heart mitochondria Journal of Biological Chemistry 2004 279 25 26036 26045 (Pubitemid 38798746)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.25
, pp. 26036-26045
-
-
Chen, R.1
Fearnley, I.M.2
Peak-Chew, S.Y.3
Walker, J.E.4
-
53
-
-
4444286595
-
Focused proteomics: Monoclonal antibody-based isolation of the oxidative phosphorylation machinery and detection of phosphoproteins using a fluorescent phosphoprotein gel stain
-
DOI 10.1002/elps.200406006
-
Murray J., Marusich M. F., Capaldi R. A., Aggeler R., Focused proteomics: monoclonal antibody-based isolation of the oxidative phosphorylation machinery and detection of phosphoproteins using a fluorescent phosphoprotein gel stain Electrophoresis 2004 25 15 2520 2525 (Pubitemid 39193661)
-
(2004)
Electrophoresis
, vol.25
, Issue.15
, pp. 2520-2525
-
-
Murray, J.1
Marusich, M.F.2
Capaldi, R.A.3
Aggeler, R.4
-
54
-
-
4444305698
-
Characterization of dynamic and steady-state protein phosphorylation using a fluorescent phosphoprotein gel stain and mass spectrometry
-
DOI 10.1002/elps.200406007
-
Schulenberg B., Goodman T. N., Aggeler R., Capaldi R. A., Patton W. F., Characterization of dynamic and steady-state protein phosphorylation using a fluorescent phosphoprotein gel stain and mass spectrometry Electrophoresis 2004 25 15 2526 2532 (Pubitemid 39193662)
-
(2004)
Electrophoresis
, vol.25
, Issue.15
, pp. 2526-2532
-
-
Schulenberg, B.1
Goodman, T.N.2
Aggeler, R.3
Capaldi, R.A.4
Patton, W.F.5
-
55
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
DOI 10.1038/33416
-
Kitada T., Asakawa S., Hattori N., Matsumine H., Yamamura Y., Minoshima S., Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism Nature 1998 392 6676 605 608 (Pubitemid 28207717)
-
(1998)
Nature
, vol.392
, Issue.6676
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
Mizuno, Y.8
Shimizu, N.9
-
56
-
-
0028198309
-
Familial juvenile parkinsonism: Clinical and pathologic study in a family
-
Takahashi H., Ohama E., Suzuki S., Horikawa Y., Ishikawa A., Morita T., Tsuji S., Ikuta F., Familial juvenile parkinsonism: clinical and pathologic study in a family Neurology 1994 44 3 I 437 441 (Pubitemid 24098141)
-
(1994)
Neurology
, vol.44
, Issue.3 I
, pp. 437-441
-
-
Takahashi, H.1
Ohama, E.2
Suzuki, S.3
Horikawa, Y.4
Ishikawa, A.5
Morita, T.6
Tsuji, S.7
Ikuta, F.8
-
57
-
-
0034848395
-
Lewy bodies and parkinsonism in families with parkin mutations
-
DOI 10.1002/ana.1132
-
Farrer M., Chan P., Chen R., Tan L., Lincoln S., Hernandez D., Forno L., Gwinn-Hardy K., Petrucelli L., Hussey J., Singleton A., Tanner C., Hardy J., Langston J. W., Lewy bodies and parkinsonism in families with parkin mutations Annals of Neurology 2001 50 3 293 300 (Pubitemid 32848731)
-
(2001)
Annals of Neurology
, vol.50
, Issue.3
, pp. 293-300
-
-
Farrer, M.1
Chan, P.2
Chen, R.3
Tan, L.4
Lincoln, S.5
Hernandez, D.6
Forno, L.7
Gwinn-Hardy, K.8
Petrucelli, L.9
Hussey, J.10
Singleton, A.11
Tanner, C.12
Hardy, J.13
Langston, J.W.14
-
58
-
-
24644462201
-
Lewy body Parkinson's disease in a large pedigree with 77 Parkin mutation carriers
-
DOI 10.1002/ana.20587
-
Pramstaller P. P., Schlossmacher M. G., Jacques T. S., Scaravilli F., Eskelson C., Pepivani I., Hedrich K., Adel S., Gonzales-McNeal M., Hilker R., Kramer P. L., Klein C., Lewy body Parkinson's disease in a large pedigree with 77 Parkin mutation carriers Annals of Neurology 2005 58 3 411 422 (Pubitemid 41266627)
-
(2005)
Annals of Neurology
, vol.58
, Issue.3
, pp. 411-422
-
-
Pramstaller, P.P.1
Schlossmacher, M.G.2
Jacques, T.S.3
Scaravilli, F.4
Eskelson, C.5
Pepivani, I.6
Hedrich, K.7
Adel, S.8
Gonzales-McNeal, M.9
Hilker, R.10
Kramer, P.L.11
Klein, C.12
-
59
-
-
18244412384
-
Molecular genetic analysis of a novel Parkin gene in Japanese families with autosomal recessive juvenile parkinsonism: Evidence for variable homozygous deletions in the Parkin gene in affected individuals
-
Hattori N., Kitada T., Matsumine H., Asakawa S., Yamamura Y., Yoshino H., Kobayashi T., Yokochi M., Wang M., Yoritaka A., Kondo T., Kuzuhara S., Nakamura S., Shimizu N., Mizuno Y., Molecular genetic analysis of a novel Parkin gene in Japanese families with autosomal recessive juvenile parkinsonism: evidence for variable homozygous deletions in the Parkin gene in affected individuals Annals of Neurology 1998 44 6 935 941 (Pubitemid 28558255)
-
(1998)
Annals of Neurology
, vol.44
, Issue.6
, pp. 935-941
-
-
Hattori, N.1
Kitada, T.2
Matsumine, H.3
Asakawa, S.4
Yamamura, Y.5
Yoshino, H.6
Kobayashi, T.7
Yokochi, M.8
Wang, M.9
Yoritaka, A.10
Kondo, T.11
Kuzuhara, S.12
Nakamura, S.13
Shimizu, N.14
Mizuno, Y.15
-
60
-
-
0345490853
-
A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe
-
Abbas N., Lcking C. B., Ricard S., Drr A., Bonifati V., De Michele G., Bouley S., Vaughan J. R., Gasser T., Marconi R., Broussolle E., Brefel-Courbon C., Harhangi B. S., Oostra B. A., Fabrizio E., Bhme G. A., Pradier L., Wood N. W., Filla A., Meco G., Denefle P., Agid Y., Brice A., A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe Human Molecular Genetics 1999 8 4 567 574 (Pubitemid 29139969)
-
(1999)
Human Molecular Genetics
, vol.8
, Issue.4
, pp. 567-574
-
-
Abbas, N.1
Lucking, C.B.2
Ricard, S.3
Durr, A.4
Bonifati, V.5
De Michele, G.6
Bouley, S.7
Vaughan, J.R.8
Gasser, T.9
Marconi, R.10
Broussolle, E.11
Brefel-Courbon, C.12
Harhangi, B.S.13
Oostra, B.A.14
Fabrizio, E.15
Bohme, G.A.16
Pradier, L.17
Wood, N.W.18
Filla, A.19
Meco, G.20
Denefle, P.21
Agid, Y.22
Brice, A.23
more..
-
61
-
-
42249091077
-
Risk of Parkinson disease in carriers of Parkin mutations: Estimation using the kin-cohort method
-
DOI 10.1001/archneur.65.4.467
-
Wang Y., Clark L. N., Louis E. D., Mejia-Santana H., Harris J., Cote L. J., Waters C., Andrews H., Ford B., Frucht S., Fahn S., Ottman R., Rabinowitz D., Marder K., Risk of Parkinson disease in carriers of Parkin mutations: estimation using the kin-cohort method Archives of Neurology 2008 65 4 467 474 (Pubitemid 351549954)
-
(2008)
Archives of Neurology
, vol.65
, Issue.4
, pp. 467-474
-
-
Wang, Y.1
Clark, L.N.2
Louis, E.D.3
Mejia-Santana, H.4
Harris, J.5
Cote, L.J.6
Waters, C.7
Andrews, H.8
Ford, B.9
Frucht, S.10
Fahn, S.11
Ottman, R.12
Rabinowitz, D.13
Marder, K.14
-
62
-
-
18444398035
-
Complex relationship between Parkin mutations and Parkinson disease
-
DOI 10.1002/ajmg.10525
-
West A., Periquet M., Lincoln S., Lcking C. B., Nicholl D., Bonifati V., Rawal N., Gasser T., Lohmann E., Deleuze J. F., Maraganore D., Levey A., Wood N., Drr A., Hardy J., Brice A., Farrer M., Complex relationship between Parkin mutations and Parkinson disease American Journal of Medical Genetics 2002 114 5 584 591 (Pubitemid 34680590)
-
(2002)
American Journal of Medical Genetics - Neuropsychiatric Genetics
, vol.114
, Issue.5
, pp. 584-591
-
-
West, A.1
Periquet, M.2
Lincoln, S.3
Lucking, C.B.4
Nicholl, D.5
Bonifati, V.6
Rawal, N.7
Gasser, T.8
Lohmann, E.9
Deleuze, J.-F.10
Maraganore, D.11
Levey, A.12
Wood, N.13
Durr, A.14
Hardy, J.15
Brice, A.16
Farrer, M.17
-
63
-
-
0033933048
-
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
-
DOI 10.1038/77060
-
Shimura H., Hattori N., Kubo S. I., Mizuno Y., Asakawa S., Minoshima S., Shimizu N., Iwai K., Chiba T., Tanaka K., Suzuki T., Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase Nature Genetics 2000 25 3 302 305 (Pubitemid 30437317)
-
(2000)
Nature Genetics
, vol.25
, Issue.3
, pp. 302-305
-
-
Shimura, H.1
Hattori, N.2
Kubo, S.-I.3
Mizuno, Y.4
Asakawa, S.5
Minoshima, S.6
Shimizu, N.7
Iwai, K.8
Chiba, T.9
Tanaka, K.10
Suzuki, T.11
-
64
-
-
0034700158
-
Parkin functions as an E2-dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1
-
Zhang Y., Gao J., Chung K. K. K., Huang H., Dawson V. L., Dawson T. M., Parkin functions as an E2-dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1 Proceedings of the National Academy of Sciences of the United States of America 2000 97 24 13354 13359
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.24
, pp. 13354-13359
-
-
Zhang, Y.1
Gao, J.2
Chung, K.K.K.3
Huang, H.4
Dawson, V.L.5
Dawson, T.M.6
-
65
-
-
76449094465
-
Parkin-mediated ubiquitin signalling in aggresome formation and autophagy
-
Chin L. S., Olzmann J. A., Li L., Parkin-mediated ubiquitin signalling in aggresome formation and autophagy Biochemical Society Transactions 2010 38 1 144 149
-
(2010)
Biochemical Society Transactions
, vol.38
, Issue.1
, pp. 144-149
-
-
Chin, L.S.1
Olzmann, J.A.2
Li, L.3
-
66
-
-
2442481789
-
Mitochondrial Dysfunction and Oxidative Damage in parkin-deficient Mice
-
DOI 10.1074/jbc.M401135200
-
Palacino J. J., Sagi D., Goldberg M. S., Krauss S., Motz C., Wacker M., Klose J., Shen J., Mitochondrial dysfunction and oxidative damage in parkin-deficient mice Journal of Biological Chemistry 2004 279 18 18614 18622 (Pubitemid 38623283)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.18
, pp. 18614-18622
-
-
Palacino, J.J.1
Sagi, D.2
Goldberg, M.S.3
Krauss, S.4
Motz, C.5
Wacker, M.6
Klose, J.7
Shen, J.8
-
67
-
-
0037386532
-
Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants
-
DOI 10.1073/pnas.0737556100
-
Greene J. C., Whitworth A. J., Kuo I., Andrews L. A., Feany M. B., Pallanck L. J., Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants Proceedings of the National Academy of Sciences of the United States of America 2003 100 7 4078 4083 (Pubitemid 36418160)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.7
, pp. 4078-4083
-
-
Greene, J.C.1
Whitworth, A.J.2
Kuo, I.3
Andrews, L.A.4
Feany, M.B.5
Pallanck, L.J.6
-
68
-
-
0037338634
-
Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death
-
DOI 10.1093/hmg/ddg044
-
Darios F., Corti O., Lcking C. B., Hampe C., Muriel M. P., Abbas N., Gu W. J., Hirsch E. C., Rooney T., Ruberg M., Brice A., Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death Human Molecular Genetics 2003 12 5 517 526 (Pubitemid 36305590)
-
(2003)
Human Molecular Genetics
, vol.12
, Issue.5
, pp. 517-526
-
-
Darios, F.1
Corti, O.2
Lucking, C.B.3
Hampe, C.4
Muriel, M.-P.5
Abbas, N.6
Gu, W.-J.7
Hirsch, E.C.8
Rooney, T.9
Ruberg, M.10
Brice, A.11
-
69
-
-
4544326057
-
Mitochondrial complex i and IV activities in leukocytes from patients with parkin mutations
-
Muftuoglu M., Elibol B., Dalmizrak O., Ercan A., Kulaksiz G., gs H., Dalkara T., zer N., Mitochondrial complex I and IV activities in leukocytes from patients with parkin mutations Movement Disorders 2004 19 5 544 548
-
(2004)
Movement Disorders
, vol.19
, Issue.5
, pp. 544-548
-
-
Muftuoglu, M.1
Elibol, B.2
Dalmizrak, O.3
Ercan, A.4
Kulaksiz, G.5
Gs, H.6
Dalkara, T.7
Zer, N.8
-
70
-
-
57749100375
-
Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts
-
Mortiboys H., Thomas K. J., Koopman W. J. H., Klaffke S., Abou-Sleiman P., Olpin S., Wood N. W., Willems P. H. G. M., Smeitink J. A. M., Cookson M. R., Bandmann O., Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts Annals of Neurology 2008 64 5 555 565
-
(2008)
Annals of Neurology
, vol.64
, Issue.5
, pp. 555-565
-
-
Mortiboys, H.1
Thomas, K.J.2
Koopman, W.J.H.3
Klaffke, S.4
Abou-Sleiman, P.5
Olpin, S.6
Wood, N.W.7
Willems, P.H.G.M.8
Smeitink, J.A.M.9
Cookson, M.R.10
Bandmann, O.11
-
71
-
-
77958535699
-
Mutant parkin impairs mitochondrial function and morphology in human fibroblasts
-
article e12962
-
Grnewald A., Voges L., Rakovic A., Kasten M., Vandebona H., Hemmelmann C., Mutant parkin impairs mitochondrial function and morphology in human fibroblasts PLoS ONE 2010 5 9, article e12962
-
(2010)
PLoS ONE
, vol.5
, Issue.9
-
-
Grnewald, A.1
Voges, L.2
Rakovic, A.3
Kasten, M.4
Vandebona, H.5
Hemmelmann, C.6
-
72
-
-
63049138430
-
Mitochondrial localization of DJ-1 leads to enhanced neuroprotection
-
Junn E., Jang W. H., Zhao X., Jeong B. S., Mouradian M. M., Mitochondrial localization of DJ-1 leads to enhanced neuroprotection Journal of Neuroscience Research 2009 87 1 123 129
-
(2009)
Journal of Neuroscience Research
, vol.87
, Issue.1
, pp. 123-129
-
-
Junn, E.1
Jang, W.H.2
Zhao, X.3
Jeong, B.S.4
Mouradian, M.M.5
-
73
-
-
40849138195
-
DJ-1 decreases Bax expression through repressing p53 transcriptional activity
-
Fan J., Ren H., Jia N., Fei E., Zhou T., Jiang P., Wu M., Wang G., DJ-1 decreases Bax expression through repressing p53 transcriptional activity Journal of Biological Chemistry 2008 283 7 4022 4030
-
(2008)
Journal of Biological Chemistry
, vol.283
, Issue.7
, pp. 4022-4030
-
-
Fan, J.1
Ren, H.2
Jia, N.3
Fei, E.4
Zhou, T.5
Jiang, P.6
Wu, M.7
Wang, G.8
-
74
-
-
54449096831
-
Synergistic activation of the human MnSOD promoter by DJ-1 and PGC-1: Regulation by SUMOylation and oxidation
-
Zhong N., Xu J., Synergistic activation of the human MnSOD promoter by DJ-1 and PGC-1 : regulation by SUMOylation and oxidation Human Molecular Genetics 2008 17 21 3357 3367
-
(2008)
Human Molecular Genetics
, vol.17
, Issue.21
, pp. 3357-3367
-
-
Zhong, N.1
Xu, J.2
-
75
-
-
48249145149
-
RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways
-
Van Der Brug M. P., Blackinton J., Chandran J., Hao L. Y., Lal A., Mazan-Mamczarz K., Martindale J., Xie C., Ahmad R., Thomas K. J., Beilina A., Gibbs J. R., Ding J., Myers A. J., Zhan M., Cai H., Bonini N. M., Gorospe M., Cookson M. R., RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways Proceedings of the National Academy of Sciences of the United States of America 2008 105 29 10244 10249
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.29
, pp. 10244-10249
-
-
Van Der Brug, M.P.1
Blackinton, J.2
Chandran, J.3
Hao, L.Y.4
Lal, A.5
Mazan-Mamczarz, K.6
Martindale, J.7
Xie, C.8
Ahmad, R.9
Thomas, K.J.10
Beilina, A.11
Gibbs, J.R.12
Ding, J.13
Myers, A.J.14
Zhan, M.15
Cai, H.16
Bonini, N.M.17
Gorospe, M.18
Cookson, M.R.19
-
76
-
-
78649866553
-
Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1
-
Guzman J. N., Sanchez-Padilla J., Wokosin D., Kondapalli J., Ilijic E., Schumacker P. T., Surmeier D. J., Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1 Nature 2010 468 7324 696 700
-
(2010)
Nature
, vol.468
, Issue.7324
, pp. 696-700
-
-
Guzman, J.N.1
Sanchez-Padilla, J.2
Wokosin, D.3
Kondapalli, J.4
Ilijic, E.5
Schumacker, P.T.6
Surmeier, D.J.7
-
77
-
-
44849093321
-
DJ-1 modulates -synuclein aggregation state in a cellular model of oxidative stress: Relevance for Parkinson's Disease and involvement of HSP70
-
article e1884
-
Batelli S., Albani D., Rametta R., Polito L., Prato F., Pesaresi M., Negro A., Forloni G., DJ-1 modulates -synuclein aggregation state in a cellular model of oxidative stress: relevance for Parkinson's Disease and involvement of HSP70 PLoS ONE 2008 3 4, article e1884
-
(2008)
PLoS ONE
, vol.3
, Issue.4
-
-
Batelli, S.1
Albani, D.2
Rametta, R.3
Polito, L.4
Prato, F.5
Pesaresi, M.6
Negro, A.7
Forloni, G.8
-
78
-
-
0030744876
-
Mutation in the α-synuclein gene identified in families with Parkinson's disease
-
DOI 10.1126/science.276.5321.2045
-
Polymeropoulos M. H., Lavedan C., Leroy E., Ide S. E., Dehejia A., Dutra A., Pike B., Root H., Rubenstein J., Boyer R., Stenroos E. S., Chandrasekharappa S., Athanassiadou A., Papapetropoulos T., Johnson W. G., Lazzarini A. M., Duvoisin R. C., Di Iorio G., Golbe L. I., Nussbaum R. L., Mutation in the -synuclein gene identified in families with Parkinson's disease Science 1997 276 5321 2045 2047 (Pubitemid 27443610)
-
(1997)
Science
, vol.276
, Issue.5321
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di Iorio, G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
79
-
-
0031990490
-
Ala30Pro mutation in the gene encoding -synuclein in Parkinson's disease
-
Krger R., Kuhn W., Mller T., Woitalla D., Graeber M., Ksel S., Przuntek H., Epplen J. T., Schls L., Riess O., Ala30Pro mutation in the gene encoding -synuclein in Parkinson's disease Nature Genetics 1998 18 2 106 108
-
(1998)
Nature Genetics
, vol.18
, Issue.2
, pp. 106-108
-
-
Krger, R.1
Kuhn, W.2
Mller, T.3
Woitalla, D.4
Graeber, M.5
Ksel, S.6
Przuntek, H.7
Epplen, J.T.8
Schls, L.9
Riess, O.10
-
80
-
-
0242300619
-
α-synuclein locus triplication causes Parkinson's disease
-
DOI 10.1126/science.1090278
-
Singleton A. B., Farrer M., Johnson J., Singleton A., Hague S., Kachergus J., Hulihan M., Peuralinna T., Dutra A., Nussbaum R., Lincoln S., Crawley A., Hanson M., Maraganore D., Adler C., Cookson M. R., Muenter M., Baptista M., Miller D., Blancato J., Hardy J., Gwinn-Hardy K., α-synuclein locus triplication causes Parkinson's disease Science 2003 302 5646 841 (Pubitemid 37339619)
-
(2003)
Science
, vol.302
, Issue.5646
, pp. 841
-
-
Singleton, A.B.1
Farrer, M.2
Johnson, J.3
Singleton, A.4
Hague, S.5
Kachergus, J.6
Hulihan, M.7
Peuralinna, T.8
Dutra, A.9
Nussbaum, R.10
Lincoln, S.11
Crawley, A.12
Hanson, M.13
Maraganore, D.14
Adler, C.15
Cookson, M.R.16
Muenter, M.17
Baptista, M.18
Miller, D.19
Blancato, J.20
Hardy, J.21
Gwinn-Hardy, K.22
more..
-
81
-
-
10744227740
-
Comparison of Kindreds with Parkinsonism and α-Synuclein Genomic Multiplications
-
DOI 10.1002/ana.10846
-
Farrer M., Kachergus J., Forno L., Lincoln S., Wang D. S., Hulihan M., Maraganore D., Gwinn-Hardy K., Wszolek Z., Dickson D., Langston J. W., Comparison of kindreds with Parkinsonism and -synuclein genomic multiplications Annals of Neurology 2004 55 2 174 179 (Pubitemid 38166993)
-
(2004)
Annals of Neurology
, vol.55
, Issue.2
, pp. 174-179
-
-
Farrer, M.1
Kachergus, J.2
Forno, L.3
Lincoln, S.4
Wang, D.-S.5
Hulihan, M.6
Maraganore, D.7
Gwinn-Hardy, K.8
Wszolek, Z.9
Dickson, D.10
Langston, J.W.11
-
82
-
-
10744230149
-
The New Mutation, E46K, of α-Synuclein Causes Parkinson and Lewy Body Dementia
-
DOI 10.1002/ana.10795
-
Zarranz J. J., Alegre J., Gmez-Esteban J. C., Lezcano E., Ros R., Ampuero I., Vidal L., Hoenicka J., Rodriguez O., Atars B., Llorens V., Gomez Tortosa E., Del Ser T., Muoz D. G., De Yebenes J. G., The new mutation, E46K, of -synuclein causes Parkinson and lewy body dementia Annals of Neurology 2004 55 2 164 173 (Pubitemid 38166992)
-
(2004)
Annals of Neurology
, vol.55
, Issue.2
, pp. 164-173
-
-
Zarranz, J.J.1
Alegre, J.2
Gomez-Esteban, J.C.3
Lezcano, E.4
Ros, R.5
Ampuero, I.6
Vidal, L.7
Hoenicka, J.8
Rodriguez, O.9
Atares, B.10
Llorens, V.11
Gomez Tortosa, E.12
Del Ser, T.13
Munoz, D.G.14
De Yebenes, J.G.15
-
83
-
-
0030882856
-
α-synuclein in Lewy bodies
-
Spillantini M. G., Schmidt M. L., Lee V. M. Y., Trojanowski J. Q., Jakes R., Goedert M., α-synuclein in Lewy bodies Nature 1997 388 6645 839 840
-
(1997)
Nature
, vol.388
, Issue.6645
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.Y.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
84
-
-
34748826792
-
Localization of α-synuclein to mitochondria within midbrain of mice
-
DOI 10.1097/WNR.0b013e3282f03db4, PII 0000175620071008000007
-
Li W. W., Yang R., Guo J. C., Ren H. M., Zha X. L., Cheng J. S., Cai D. F., Localization of α-synuclein to mitochondria within midbrain of mice NeuroReport 2007 18 15 1543 1546 (Pubitemid 47476380)
-
(2007)
NeuroReport
, vol.18
, Issue.15
, pp. 1543-1546
-
-
Li, W.-W.1
Yang, R.2
Guo, J.-C.3
Ren, H.-M.4
Zha, X.-L.5
Cheng, J.-S.6
Cai, D.-F.7
-
85
-
-
58149379599
-
Optical reporters for the conformation of -synuclein reveal a specific interaction with mitochondria
-
Nakamura K., Nemani V. M., Wallender E. K., Kaehlcke K., Ott M., Edwards R. H., Optical reporters for the conformation of -synuclein reveal a specific interaction with mitochondria Journal of Neuroscience 2008 28 47 12305 12317
-
(2008)
Journal of Neuroscience
, vol.28
, Issue.47
, pp. 12305-12317
-
-
Nakamura, K.1
Nemani, V.M.2
Wallender, E.K.3
Kaehlcke, K.4
Ott, M.5
Edwards, R.H.6
-
86
-
-
63449093494
-
α-Synuclein is differentially expressed in mitochondria from different rat brain regions and dose-dependently down-regulates complex i activity
-
Liu G., Zhang C., Yin J., Li X., Cheng F., Li Y., Yang H., Uda K., Chan P., Yu S., α-Synuclein is differentially expressed in mitochondria from different rat brain regions and dose-dependently down-regulates complex I activity Neuroscience Letters 2009 454 3 187 192
-
(2009)
Neuroscience Letters
, vol.454
, Issue.3
, pp. 187-192
-
-
Liu, G.1
Zhang, C.2
Yin, J.3
Li, X.4
Cheng, F.5
Li, Y.6
Yang, H.7
Uda, K.8
Chan, P.9
Yu, S.10
-
87
-
-
44049099669
-
Mitochondrial import and accumulation of -synuclein impair complex i in human dopaminergic neuronal cultures and Parkinson disease brain
-
Devi L., Raghavendran V., Prabhu B. M., Avadhani N. G., Anandatheerthavarada H. K., Mitochondrial import and accumulation of -synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain Journal of Biological Chemistry 2008 283 14 9089 9100
-
(2008)
Journal of Biological Chemistry
, vol.283
, Issue.14
, pp. 9089-9100
-
-
Devi, L.1
Raghavendran, V.2
Prabhu, B.M.3
Avadhani, N.G.4
Anandatheerthavarada, H.K.5
-
88
-
-
77951290337
-
α-synuclein induced membrane depolarization and loss of phosphorylation capacity of isolated rat brain mitochondria: Implications in Parkinson's disease
-
Banerjee K., Sinha M., Pham C. L. L., Jana S., Chanda D., Cappai R., Chakrabarti S., α-synuclein induced membrane depolarization and loss of phosphorylation capacity of isolated rat brain mitochondria: implications in Parkinson's disease FEBS Letters 2010 584 8 1571 1576
-
(2010)
FEBS Letters
, vol.584
, Issue.8
, pp. 1571-1576
-
-
Banerjee, K.1
Sinha, M.2
Pham, C.L.L.3
Jana, S.4
Chanda, D.5
Cappai, R.6
Chakrabarti, S.7
-
89
-
-
77958450202
-
Inhibition of mitochondrial fusion by -synuclein is rescued by PINK1, Parkin and DJ-1
-
Kamp F., Exner N., Lutz A. K., Wender N., Hegermann J., Brunner B., Nuscher B., Bartels T., Giese A., Beyer K., Eimer S., Winklhofer K. F., Haass C., Inhibition of mitochondrial fusion by -synuclein is rescued by PINK1, Parkin and DJ-1 EMBO Journal 2010 29 20 3571 3589
-
(2010)
EMBO Journal
, vol.29
, Issue.20
, pp. 3571-3589
-
-
Kamp, F.1
Exner, N.2
Lutz, A.K.3
Wender, N.4
Hegermann, J.5
Brunner, B.6
Nuscher, B.7
Bartels, T.8
Giese, A.9
Beyer, K.10
Eimer, S.11
Winklhofer, K.F.12
Haass, C.13
-
90
-
-
30644471051
-
Parkinson's disease α-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death
-
DOI 10.1523/JNEUROSCI.4308-05.2006
-
Martin L. J., Pan Y., Price A. C., Sterling W., Copeland N. G., Jenkins N. A., Price D. L., Lee M. K., Parkinson's disease -synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death Journal of Neuroscience 2006 26 1 41 50 (Pubitemid 43089519)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.1
, pp. 41-50
-
-
Martin, L.J.1
Pan, Y.2
Price, A.C.3
Sterling, W.4
Copeland, N.G.5
Jenkins, N.A.6
Price, D.L.7
Lee, M.K.8
-
91
-
-
67650496503
-
Relationship between alpha synuclein phosphorylation, proteasomal inhibition and cell death: Relevance to Parkinson's disease pathogenesis
-
Chau K. Y., Ching H. L., Schapira A. H. V., Cooper J. M., Relationship between alpha synuclein phosphorylation, proteasomal inhibition and cell death: relevance to Parkinson's disease pathogenesis Journal of Neurochemistry 2009 110 3 1005 1013
-
(2009)
Journal of Neurochemistry
, vol.110
, Issue.3
, pp. 1005-1013
-
-
Chau, K.Y.1
Ching, H.L.2
Schapira, A.H.V.3
Cooper, J.M.4
-
92
-
-
77949623516
-
Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1
-
article e9367
-
Krebiehl G., Ruckerbauer S., Burbulla L. F., Kieper N., Maurer B., Waak J., Wolburg H., Gizatullina Z., Gellerich F. N., Woitalla D., Riess O., Kahle P. J., Proikas-Cezanne T., Krger R., Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1 PLoS ONE 2010 5 2, article e9367
-
(2010)
PLoS ONE
, vol.5
, Issue.2
-
-
Krebiehl, G.1
Ruckerbauer, S.2
Burbulla, L.F.3
Kieper, N.4
Maurer, B.5
Waak, J.6
Wolburg, H.7
Gizatullina, Z.8
Gellerich, F.N.9
Woitalla, D.10
Riess, O.11
Kahle, P.J.12
Proikas-Cezanne, T.13
Krger, R.14
-
93
-
-
77956522541
-
Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics
-
Irrcher I., Aleyasin H., Seifert E. L., Hewitt S. J., Chhabra S., Phillips M., Lutz A. K., Rousseaux M. W.C., Bevilacqua L., Jahani-Asl A., Callaghan S., MacLaurin J. G., Winklhofer K. F., Rizzu P., Rippstein P., Kim R. H., Chen C. X., Fon E. A., Slack R. S., Harper M. E., McBride H. M., Mak T. W., Park D. S., Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics Human Molecular Genetics 2010 19 19 3734 3746
-
(2010)
Human Molecular Genetics
, vol.19
, Issue.19
, pp. 3734-3746
-
-
Irrcher, I.1
Aleyasin, H.2
Seifert, E.L.3
Hewitt, S.J.4
Chhabra, S.5
Phillips, M.6
Lutz, A.K.7
Rousseaux, M.W.C.8
Bevilacqua, L.9
Jahani-Asl, A.10
Callaghan, S.11
MacLaurin, J.G.12
Winklhofer, K.F.13
Rizzu, P.14
Rippstein, P.15
Kim, R.H.16
Chen, C.X.17
Fon, E.A.18
Slack, R.S.19
Harper, M.E.20
McBride, H.M.21
Mak, T.W.22
Park, D.S.23
more..
-
94
-
-
69249096578
-
Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation
-
Lutz A. K., Exner N., Fett M. E., Schleke J. S., Kloos K., Lmmermann K., Brunner B., Kurz-Drexler A., Vogel F., Reichert A. S., Bouman L., Vogt-Weisenhorn D., Wurst W., Tatzelt J., Haass C., Winklhofer K. F., Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation Journal of Biological Chemistry 2009 284 34 22938 22951
-
(2009)
Journal of Biological Chemistry
, vol.284
, Issue.34
, pp. 22938-22951
-
-
Lutz, A.K.1
Exner, N.2
Fett, M.E.3
Schleke, J.S.4
Kloos, K.5
Lmmermann, K.6
Brunner, B.7
Kurz-Drexler, A.8
Vogel, F.9
Reichert, A.S.10
Bouman, L.11
Vogt-Weisenhorn, D.12
Wurst, W.13
Tatzelt, J.14
Haass, C.15
Winklhofer, K.F.16
-
95
-
-
66349123690
-
Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1
-
article e5701
-
Sandebring A., Thomas K. J., Beilina A., van der Brug M., Cleland M. M., Ahmad R., Miller D. W., Zambrano I., Cowburn R. F., Behbahani H., Cedazo-Mnguez A., Cookson M. R., Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1 PLoS ONE 2009 4 5, article e5701
-
(2009)
PLoS ONE
, vol.4
, Issue.5
-
-
Sandebring, A.1
Thomas, K.J.2
Beilina, A.3
Van Der Brug, M.4
Cleland, M.M.5
Ahmad, R.6
Miller, D.W.7
Zambrano, I.8
Cowburn, R.F.9
Behbahani, H.10
Cedazo-Mnguez, A.11
Cookson, M.R.12
-
96
-
-
55749090654
-
The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
-
Deng H., Dodson M. W., Huang H., Guo M., The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila Proceedings of the National Academy of Sciences of the United States of America 2008 105 38 14503 14508
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.38
, pp. 14503-14508
-
-
Deng, H.1
Dodson, M.W.2
Huang, H.3
Guo, M.4
-
97
-
-
44349195101
-
Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery
-
DOI 10.1073/pnas.0711845105
-
Yang Y., Ouyang Y., Yang L., Beal M. F., McQuibban A., Vogel H., Lu B., Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery Proceedings of the National Academy of Sciences of the United States of America 2008 105 19 7070 7075 (Pubitemid 351754531)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.19
, pp. 7070-7075
-
-
Yang, Y.1
Ouyang, Y.2
Yang, L.3
Beal, M.F.4
McQuibban, A.5
Vogel, H.6
Lu, B.7
-
98
-
-
39449088321
-
The PINK1/Parkin pathway regulates mitochondrial morphology
-
DOI 10.1073/pnas.0709336105
-
Poole A. C., Thomas R. E., Andrews L. A., McBride H. M., Whitworth A. J., Pallanck L. J., The PINK1/Parkin pathway regulates mitochondrial morphology Proceedings of the National Academy of Sciences of the United States of America 2008 105 5 1638 1643 (Pubitemid 351346567)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.5
, pp. 1638-1643
-
-
Poole, A.C.1
Thomas, R.E.2
Andrews, L.A.3
McBride, H.M.4
Whitworth, A.J.5
Pallanck, L.J.6
-
99
-
-
67649399288
-
Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission
-
Dagda R. K., Cherra S. J. III, Kulich S. M., Tandon A., Park D., Chu C. T., Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission Journal of Biological Chemistry 2009 284 20 13843 13855
-
(2009)
Journal of Biological Chemistry
, vol.284
, Issue.20
, pp. 13843-13855
-
-
Dagda, R.K.1
Iii, J.C.S.2
Kulich, S.M.3
Tandon, A.4
Park, D.5
Chu, C.T.6
-
100
-
-
75949098487
-
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
-
Vives-Bauza C., Zhou C., Huang Y., Cui M., De Vries R. L. A., Kim J., May J., Tocilescu M. A., Liu W., Ko H. S., Magran J., Moore D. J., Dawson V. L., Grailhe R., Dawson T. M., Li C., Tieu K., Przedborski S., PINK1-dependent recruitment of Parkin to mitochondria in mitophagy Proceedings of the National Academy of Sciences of the United States of America 2010 107 1 378 383
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, Issue.1
, pp. 378-383
-
-
Vives-Bauza, C.1
Zhou, C.2
Huang, Y.3
Cui, M.4
De Vries, R.L.A.5
Kim, J.6
May, J.7
Tocilescu, M.A.8
Liu, W.9
Ko, H.S.10
Magran, J.11
Moore, D.J.12
Dawson, V.L.13
Grailhe, R.14
Dawson, T.M.15
Li, C.16
Tieu, K.17
Przedborski, S.18
-
101
-
-
77953877676
-
A pivotal role for PINK1 and autophagy in mitochondrial quality control: Implications for Parkinson disease
-
Chu C. T., A pivotal role for PINK1 and autophagy in mitochondrial quality control: implications for Parkinson disease Human Molecular Genetics 2010 19 1 R28 R37
-
(2010)
Human Molecular Genetics
, vol.19
, Issue.1
-
-
Chu, C.T.1
-
102
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
Narendra D., Tanaka A., Suen D. F., Youle R. J., Parkin is recruited selectively to impaired mitochondria and promotes their autophagy Journal of Cell Biology 2008 183 5 795 803
-
(2008)
Journal of Cell Biology
, vol.183
, Issue.5
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
103
-
-
56049091236
-
PINK1 controls mitochondrial localization of Parkin through direct phosphorylation
-
Kim Y., Park J., Kim S., Song S., Kwon S. K., Lee S. H., Kitada T., Kim J. M., Chung J., PINK1 controls mitochondrial localization of Parkin through direct phosphorylation Biochemical and Biophysical Research Communications 2008 377 3 975 980
-
(2008)
Biochemical and Biophysical Research Communications
, vol.377
, Issue.3
, pp. 975-980
-
-
Kim, Y.1
Park, J.2
Kim, S.3
Song, S.4
Kwon, S.K.5
Lee, S.H.6
Kitada, T.7
Kim, J.M.8
Chung, J.9
-
104
-
-
75749156257
-
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
-
article e1000298
-
Narendra D. P., Jin S. M., Tanaka A., Suen D. F., Gautier C. A., Shen J., Cookson M. R., Youle R. J., PINK1 is selectively stabilized on impaired mitochondria to activate Parkin PLoS Biology 2010 8 1, article e1000298
-
(2010)
PLoS Biology
, vol.8
, Issue.1
-
-
Narendra, D.P.1
Jin, S.M.2
Tanaka, A.3
Suen, D.F.4
Gautier, C.A.5
Shen, J.6
Cookson, M.R.7
Youle, R.J.8
-
106
-
-
78649463381
-
Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
-
Gegg M. E., Cooper J. M., Chau K.-Y., Rojo M., Schapira A. H. V., Taanman J.-W., Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin- dependent manner upon induction of mitophagy Human Molecular Genetics 2010 19 24 4861 4870
-
(2010)
Human Molecular Genetics
, vol.19
, Issue.24
, pp. 4861-4870
-
-
Gegg, M.E.1
Cooper, J.M.2
Chau, K.-Y.3
Rojo, M.4
Schapira, A.H.V.5
Taanman, J.-W.6
-
107
-
-
79956323688
-
DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy
-
Thomas K. J., McCoy M. K., Blackinton J., Beilina A., van der B. M., Sandebring A., DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy Human Molecular Genetics 2010 20 1 40 50
-
(2010)
Human Molecular Genetics
, vol.20
, Issue.1
, pp. 40-50
-
-
Thomas, K.J.1
McCoy, M.K.2
Blackinton, J.3
Beilina, A.4
Van Der, B.M.5
Sandebring, A.6
-
109
-
-
35748935851
-
The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1
-
DOI 10.1038/ncb1644, PII NCB1644
-
Plun-Favreau H., Klupsch K., Moisoi N., Gandhi S., Kjaer S., Frith D., Harvey K., Deas E., Harvey R. J., McDonald N., Wood N. W., Martins M. L., Downward J., The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1 Nature Cell Biology 2007 9 11 1243 1252 (Pubitemid 350042356)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.11
, pp. 1243-1252
-
-
Plun-Favreau, H.1
Klupsch, K.2
Moisoi, N.3
Gandhi, S.4
Kjaer, S.5
Frith, D.6
Harvey, K.7
Deas, E.8
Harvey, R.J.9
McDonald, N.10
Wood, N.W.11
Martins, M.L.12
Downward, J.13
-
110
-
-
25444498785
-
Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease
-
DOI 10.1093/hmg/ddi215
-
Strauss K. M., Martins L. M., Plun-Favreau H., Marx F. P., Kautzmann S., Berg D., Gasser T., Wszolek Z., Mller T., Bornemann A., Wolburg H., Downward J., Riess O., Schulz J. B., Krger R., Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease Human Molecular Genetics 2005 14 15 2099 2111 (Pubitemid 41418010)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.15
, pp. 2099-2111
-
-
Strauss, K.M.1
Martins, L.M.2
Plun-Favreau, H.3
Marx, F.P.4
Kautzmann, S.5
Berg, D.6
Gasser, T.7
Wszolek, Z.8
Muller, T.9
Bornemann, A.10
Wolburg, H.11
Downward, J.12
Riess, O.13
Schulz, J.B.14
Kruger, R.15
-
111
-
-
44849115171
-
Genetic variability in the mitochondrial serine protease HTRA2 contributes to risk for Parkinson disease
-
DOI 10.1002/humu.20713
-
Bogaerts V., Nuytemans K., Reumers J., Pals P., Engelborghs S., Pickut B., Corsmit E., Peeters K., Schymkowitz J., De Deyn P. P., Cras P., Rousseau F., Theuns J., Van Broeckhoven C., Genetic variability in the mitochondrial serine protease HTRA2 contributes to risk for Parkinson disease Human Mutation 2008 29 6 832 840 (Pubitemid 351794134)
-
(2008)
Human Mutation
, vol.29
, Issue.6
, pp. 832-840
-
-
Bogaerts, V.1
Nuytemans, K.2
Reumers, J.3
Pals, P.4
Engelborghs, S.5
Pickut, B.6
Corsmit, E.7
Peeters, K.8
Schymkowitz, J.9
De Deyn, P.P.10
Cras, P.11
Rousseau, F.12
Theuns, J.13
Van Broeckhoven, C.14
-
112
-
-
34547127902
-
PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1
-
article e172
-
Pridgeon J. W., Olzmann J. A., Chin L. S., Li L., PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1 PLoS Biology 2007 5 7, article e172
-
(2007)
PLoS Biology
, vol.5
, Issue.7
-
-
Pridgeon, J.W.1
Olzmann, J.A.2
Chin, L.S.3
Li, L.4
-
113
-
-
78149469728
-
Chaperone-mediated autophagy markers in Parkinson disease brains
-
Alvarez-Erviti L., Rodriguez-Oroz M. C., Cooper J. M., Caballero C., Ferrer I., Obeso J. A., Schapira A. H.V., Chaperone-mediated autophagy markers in Parkinson disease brains Archives of Neurology 2010 67 12 1464 1472
-
(2010)
Archives of Neurology
, vol.67
, Issue.12
, pp. 1464-1472
-
-
Alvarez-Erviti, L.1
Rodriguez-Oroz, M.C.2
Cooper, J.M.3
Caballero, C.4
Ferrer, I.5
Obeso, J.A.6
Schapira, A.H.V.7
-
114
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
-
Betarbet R., Sherer T. B., MacKenzie G., Garcia-Osuna M., Panov A. V., Greenamyre J. T., Chronic systemic pesticide exposure reproduces features of Parkinson's disease Nature Neuroscience 2000 3 12 1301 1306
-
(2000)
Nature Neuroscience
, vol.3
, Issue.12
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.B.2
MacKenzie, G.3
Garcia-Osuna, M.4
Panov, A.V.5
Greenamyre, J.T.6
-
115
-
-
70349798628
-
Natural lipophilic inhibitors of mitochondrial complex i are candidate toxins for sporadic neurodegenerative tau pathologies
-
Hllerhage M., Matusch A., Champy P., Lombs A., Ruberg M., Oertel W. H., Hglinger G. U., Natural lipophilic inhibitors of mitochondrial complex I are candidate toxins for sporadic neurodegenerative tau pathologies Experimental Neurology 2009 220 1 133 142
-
(2009)
Experimental Neurology
, vol.220
, Issue.1
, pp. 133-142
-
-
Hllerhage, M.1
Matusch, A.2
Champy, P.3
Lombs, A.4
Ruberg, M.5
Oertel, W.H.6
Hglinger, G.U.7
-
116
-
-
77954657877
-
Complex I: Inhibitors, inhibition and neurodegeneration
-
Schapira A. H. V., Complex I: inhibitors, inhibition and neurodegeneration Experimental Neurology 2010 224 2 331 335
-
(2010)
Experimental Neurology
, vol.224
, Issue.2
, pp. 331-335
-
-
Schapira, A.H.V.1
-
117
-
-
33846996820
-
Pesticide exposure and self-reported Parkinson's disease in the agricultural health study
-
Kamel F., Tanner C. M., Umbach D. M., Hoppin J. A., Alavanja M. C. R., Blair A., Comyns K., Goldman S. M., Korell M., Langston J. W., Ross G. W., Sandler D. P., Pesticide exposure and self-reported Parkinson's disease in the agricultural health study American Journal of Epidemiology 2007 165 4 364 374
-
(2007)
American Journal of Epidemiology
, vol.165
, Issue.4
, pp. 364-374
-
-
Kamel, F.1
Tanner, C.M.2
Umbach, D.M.3
Hoppin, J.A.4
Alavanja, M.C.R.5
Blair, A.6
Comyns, K.7
Goldman, S.M.8
Korell, M.9
Langston, J.W.10
Ross, G.W.11
Sandler, D.P.12
-
118
-
-
9744276661
-
Pramipexole protects against apoptotic cell death by non-dopaminergic mechanisms
-
DOI 10.1111/j.1471-4159.2004.02804.x
-
Gu M., Irvani M., Cooper J. M., King D., Jenner P., Schapira A. H. V., Pramipexole protects against apoptotic cell death by non-dopaminergic mechanisms Journal of Neurochemistry 2004 91 5 1075 1081 (Pubitemid 39587446)
-
(2004)
Journal of Neurochemistry
, vol.91
, Issue.5
, pp. 1075-1081
-
-
Gu, M.1
Irvani, M.2
Cooper, J.M.3
King, D.4
Jenner, P.5
Schapira, A.H.V.6
-
119
-
-
0036771852
-
Effects of coenzyme Q in early Parkinson disease: Evidence of slowing of the functional decline
-
Shults C. W., Oakes D., Kieburtz K., Flint Beal M., Haas R., Plumb S., Juncos J. L., Nutt J., Shoulson I., Carter J., Kompoliti K., Perlmutter J. S., Reich S., Stern M., Watts R. L., Kurlan R., Molho E., Harrison M., Lew M., Effects of coenzyme Q in early Parkinson disease: evidence of slowing of the functional decline Archives of Neurology 2002 59 10 1541 1550
-
(2002)
Archives of Neurology
, vol.59
, Issue.10
, pp. 1541-1550
-
-
Shults, C.W.1
Oakes, D.2
Kieburtz, K.3
Flint Beal, M.4
Haas, R.5
Plumb, S.6
Juncos, J.L.7
Nutt, J.8
Shoulson, I.9
Carter, J.10
Kompoliti, K.11
Perlmutter, J.S.12
Reich, S.13
Stern, M.14
Watts, R.L.15
Kurlan, R.16
Molho, E.17
Harrison, M.18
Lew, M.19
-
120
-
-
33846115045
-
A randomized clinical trial of coenzyme Q10 and GPI-1485 in early Parkinson disease
-
DOI 10.1212/01.wnl.0000250355.28474.8e, PII 0000611420070102000009
-
Kieburtz K., Ravina B., Galpern W. R., Tilley B., Shannon K., Tanner C., Wooten G. F., Hamill R., Sage J. I., Kosa E., Watts R. L., Stover N. R., McMurray R., Lew M. F., Kawai C., Coffey D., LeBlanc P., Carter J., Brodsky M., Andrews P., Siderowf A., Reichwein S., Shulman L., Weiner W. J., Pabst K., Jaglin J., Hauser R., McClain T., Delgado H., Suchowersky O., Derwent L., Rao J., Cook M., Aminoff M. J., Christine C., Roth J., Leehey M., Bainbridge J., Ross G. W., Terashita S., Singer C., Perez M. A., Blenke A., Racette B., Deppen P., Elble R., Young C., Stewart T., Sethi K., Dill B., Taylor J., Roberge P., Dewey Jr. R. B., Hayward B., Jankovic J., Hunter C., Wooten F., Keller M. F., Jennings D., Kelsey T., Martin W., McInnes G., Wojcieszek J., Belden J., Albin R., Wernette K., Savitt J., Dunlop B., Pahwa R., Lyons K. E., Parsons A., Fang J., Shearon D., Feigin A., Cox M. M., Adler C., Lind M., Scott B., Field J., Nance M., Peterson S., Burns R. S., Marlor L., Van Bodis-Wollner I., Hayes E., Schneider J., Sendek S., Gollomp S., Vernon G., LeWitt P., DeAngelis M., Simon D., Paul L., Gorell J., Krstevska S., Flewellen M., McCarthy S., Uitti R., Turk M., Bower J., Torgrimson S., Sabbagh M., Obradov Z., Juncos J., Weeks M. L.M., Fernandez H., Brown G., Elm J., Guimaraes P., Huang P., Palesch Y., Kamp C., Shinaman A., Fraser D., Brocht A., Bennett S., Weaver C., Baker D., Olsen B., Goetz C., Miyasaki J., Fagan S., Mauldin P., A randomized clinical trial of
-
(2007)
Neurology
, vol.68
, Issue.1
, pp. 20-28
-
-
Kieburtz, K.1
Ravina, B.2
Galpern, W.R.3
Tilley, B.4
Shannon, K.5
Tanner, C.6
Wooten, G.F.7
Hamill, R.8
Sage, J.I.9
Kosa, E.10
Watts, R.L.11
Stover, N.R.12
McMurray, R.13
Lew, M.F.14
Kawai, C.15
Coffey, D.16
LeBlanc, P.17
Carter, J.18
Brodsky, M.19
Andrews, P.20
Siderowf, A.21
Reichwein, S.22
Shulman, L.23
Weiner, W.J.24
Pabst, K.25
Jaglin, J.26
Hauser, R.27
McClain, T.28
Delgado, H.29
Suchowersky, O.30
Derwent, L.31
Rao, J.32
Cook, M.33
Aminoff, M.J.34
Christine, C.35
Roth, J.36
Leehey, M.37
Bainbridge, J.38
Ross, G.W.39
Terashita, S.40
Singer, C.41
Perez, M.A.42
Blenke, A.43
Racette, B.44
Deppen, P.45
Elble, R.46
Young, C.47
Stewart, T.48
Sethi, K.49
Dill, B.50
Taylor, J.51
Roberge, P.52
Dewey Jr., R.B.53
Hayward, B.54
Jankovic, J.55
Hunter, C.56
Wooten, F.57
Keller, M.F.58
Jennings, D.59
Kelsey, T.60
Martin, W.61
McInnes, G.62
Wojcieszek, J.63
Belden, J.64
Albin, R.65
Wernette, K.66
Savitt, J.67
Dunlop, B.68
Pahwa, R.69
Lyons, K.E.70
Parsons, A.71
Fang, J.72
Shearon, D.73
Feigin, A.74
Cox, M.M.75
Adler, C.76
Lind, M.77
Scott, B.78
Field, J.79
Nance, M.80
Peterson, S.81
Burns, R.S.82
Marlor, L.83
Van Bodis-Wollner, I.84
Hayes, E.85
Schneider, J.86
Sendek, S.87
Gollomp, S.88
Vernon, G.89
LeWitt, P.90
DeAngelis, M.91
Simon, D.92
Paul, L.93
Gorell, J.94
Krstevska, S.95
Flewellen, M.96
McCarthy, S.97
Uitti, R.98
Turk, M.99
more..
|