Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1

PLoS ONE

Volumn 4, Issue 5, 2009, Pages

  Sandebring, Anna ^a,b   Thomas, Kelly Jean ^a   Beilina, Alexandra ^a   van der Brug, Marcel ^a,d   Cleland, Megan M ^c   Ahmad, Rili ^a,e   Miller, David W ^a   Zambrano, Ibardo ^a   Cowburn, Richard F ^b   Behbahani, Homira ^b   Cedazo Mínguez, Angel ^b   Cookson, Mark R ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

^c NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

^e ASTRAZENECA R AND D   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; DYNAMIN; DYNAMIN RELATED PROTEIN 1; ENZYME INHIBITOR; GUANOSINE TRIPHOSPHATASE; LENTIVIRUS VECTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE INDUCED KINASE 1; PROTEIN KINASE; PROTEIN PINK1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE; TACROLIMUS; UNCLASSIFIED DRUG; DNM1L PROTEIN, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; MITOCHONDRIAL PROTEIN; PTEN INDUCED PUTATIVE KINASE; PTEN-INDUCED PUTATIVE KINASE;

ARTICLE; CELL FUNCTION; CELL LINE; CELL STRUCTURE; CELL VIABILITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PHENOTYPE; PROTEIN CROSS LINKING; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; RNA INTERFERENCE; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING; WILD TYPE; BIOLOGICAL MODEL; CELL SURVIVAL; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; GENE SILENCING; METABOLISM; MITOCHONDRION; PHOSPHORYLATION; ULTRASTRUCTURE;

CALCINEURIN; CELL LINE; CELL SURVIVAL; ENZYME ACTIVATION; GENE KNOCKDOWN TECHNIQUES; GTP PHOSPHOHYDROLASES; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MODELS, BIOLOGICAL; PHENOTYPE; PHOSPHORYLATION; PROTEIN KINASES; ROTENONE;

EID: 66349123690     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0005701     Document Type: Article

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