메뉴 건너뛰기




Volumn 30, Issue 2-3, 2011, Pages 150-182

Adjuvants for enhancing the immunogenicity of whole tumor cell vaccines

Author keywords

adjuvants; cytokines; immunogenicity; ovarian carcinoma; Toll like receptor agonists; Whole tumor cell vaccine

Indexed keywords

ALUMINUM POTASSIUM SULFATE; BCG VACCINE; BEVACIZUMAB; CISPLATIN; CPG OLIGODEOXYNUCLEOTIDE; CYCLOPHOSPHAMIDE; DENDRITIC CELL VACCINE; DOCETAXEL; DOXORUBICIN; GAMMA INTERFERON; GEMCITABINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR VACCINE; HYPOCHLOROUS ACID; IMMUNOLOGICAL ADJUVANT; KEYHOLE LIMPET HEMOCYANIN; LIPOSOME; MACROPHAGE ACTIVATING LIPOPEPTIDE 2; MELACINE; MONTANIDE ISA 51; PHOSPHORYL LIPID A; PLACEBO; POLYINOSINIC POLYCYTIDYLIC ACID; PREDNISONE; RINTATOLIMOD; TOLL LIKE RECEPTOR AGONIST; TUMOR CELL VACCINE; UNINDEXED DRUG; VIRUS ONCOLYSATE; WART VIRUS VACCINE;

EID: 79955859969     PISSN: 08830185     EISSN: 15635244     Source Type: Journal    
DOI: 10.3109/08830185.2011.572210     Document Type: Article
Times cited : (94)

References (223)
  • 3
    • 0034614897 scopus 로고    scopus 로고
    • Consequences of cell death: Exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells
    • Sauter B, Albert ML, Francisco L, et al. Consequences of cell death: Exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells. J Exp Med 2000;191:423-434.
    • (2000) J Exp Med , vol.191 , pp. 423-434
    • Sauter, B.1    Albert, M.L.2    Francisco, L.3
  • 4
    • 0035500779 scopus 로고    scopus 로고
    • Primary tumor tissue lysates are enriched in heat shock proteins and induce the maturation of human dendritic cells
    • Somersan S, Larsson M, Fonteneau JF, et al. Primary tumor tissue lysates are enriched in heat shock proteins and induce the maturation of human dendritic cells. J Immunol 2001;167:4844-4852. (Pubitemid 33009712)
    • (2001) Journal of Immunology , vol.167 , Issue.9 , pp. 4844-4852
    • Somersan, S.1    Larsson, M.2    Fonteneau, J.F.3    Basu, S.4    Srivastava, P.5    Bhardwaj, N.6
  • 6
    • 33746190863 scopus 로고    scopus 로고
    • Extracellular targeting of endoplasmic reticulum chaperone glucose-regulated protein 170 enhances tumor immunity to a poorly immunogenic melanoma
    • Wang X-Y, Arnouk H, Chen X, et al. Extracellular targeting of endoplasmic reticulum chaperone glucose-regulated protein 170 enhances tumor immunity to a poorly immunogenic melanoma. J Immunol 2006;177:1543-1551. (Pubitemid 44092488)
    • (2006) Journal of Immunology , vol.177 , Issue.3 , pp. 1543-1551
    • Wang, X.-Y.1    Arnouk, H.2    Chen, X.3    Kazim, L.4    Repasky, E.A.5    Subjeck, J.R.6
  • 7
    • 0037062934 scopus 로고    scopus 로고
    • Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
    • DOI 10.1038/nature00858
    • Scafdi P, Misteli T, Bianchi ME. Release of chromatin protein HMGB1 by necrotic cells triggers infammation. Nature 2002;418:191-195. (Pubitemid 34773774)
    • (2002) Nature , vol.418 , Issue.6894 , pp. 191-195
    • Scaffidi, P.1    Misteli, T.2    Bianchi, M.E.3
  • 10
    • 3442885649 scopus 로고    scopus 로고
    • Uric acid promotes tumor immune rejection
    • DOI 10.1158/0008-5472.CAN-04-1586
    • Hu D-E, Moore AM, Tomsen LL, Brindle KM. Uric acid promotes tumor immune rejection. Cancer Res 2004;64:5059-5062. (Pubitemid 39006518)
    • (2004) Cancer Research , vol.64 , Issue.15 , pp. 5059-5062
    • Hu, D.-E.1    Moore, A.M.2    Thomsen, L.L.3    Brindle, K.M.4
  • 11
    • 0141998606 scopus 로고    scopus 로고
    • Molecular identification of a danger signal that alerts the immune system to dying cells
    • DOI 10.1038/nature01991
    • Shi Y, Evans JE, Rock KL. Molecular identifcation of a danger signal that alerts the immune system to dying cells. Nature 2003;425:516-521. (Pubitemid 37237047)
    • (2003) Nature , vol.425 , Issue.6957 , pp. 516-521
    • Shi, Y.1    Evans, J.E.2    Rock, K.L.3
  • 12
    • 0030937833 scopus 로고    scopus 로고
    • Capture and processing of exogenous antigens for presentation on MHC molecules
    • DOI 10.1146/annurev.immunol.15.1.821
    • Watts C. Capture and processing of exogenous antigens for presentation on MHC molecules. Annu Rev Immunol 1997;15:821-850. (Pubitemid 27169300)
    • (1997) Annual Review of Immunology , vol.15 , pp. 821-850
    • Watts, C.1
  • 14
    • 60849084473 scopus 로고    scopus 로고
    • Prolonged survival of dendritic cell-vaccinated melanoma patients correlates with tumor-Specific delayed Type IV hypersensitivity response and reduction of tumor growth factor (beta)-expressing T cells
    • Lopez MN, Pereda C, Segal G, et al. Prolonged survival of dendritic cell-vaccinated melanoma patients correlates with tumor-Specific delayed Type IV hypersensitivity response and reduction of tumor growth factor (beta)-expressing T cells. J Clin Oncol 2009;27:945-952.
    • (2009) J Clin Oncol , vol.27 , pp. 945-952
    • Lopez, M.N.1    Pereda, C.2    Segal, G.3
  • 15
    • 0036181959 scopus 로고    scopus 로고
    • Vaccination with autologous tumour antigen-pulsed dendritic cells in advanced gynaecological malignancies: Clinical and immunological evaluation of a phase I trial
    • DOI 10.1007/s00262-001-0255-1
    • Hernando J, Park T, Kübler K, et al. Vaccination with autologous tumour antigen-pulsed dendritic cells in advanced gynaecological malignancies: Clinical and immunological evaluation of a phase I trial. Cancer Immunol Immunother 2002;51:45-52. (Pubitemid 34158522)
    • (2002) Cancer Immunology, Immunotherapy , vol.51 , Issue.1 , pp. 45-52
    • Hernando, J.1    Park, T.-W.2    Kubler, K.3    Offergeld, R.4    Schlebusch, H.5    Bauknecht, T.6
  • 19
    • 0034920535 scopus 로고    scopus 로고
    • Dendritic cells resurrect antigens from dead cells
    • DOI 10.1016/S1471-4906(01)01860-9, PII S1471490601018609
    • Larsson M, Fonteneau JF, Bhardwaj N. Dendritic cells resurrect antigens from dead cells. Trends Immunol 2001;22:141-148. (Pubitemid 32675261)
    • (2001) Trends in Immunology , vol.22 , Issue.3 , pp. 141-148
    • Larsson, M.1    Fonteneau, J.F.2    Bhardwaj, N.3
  • 20
    • 0034662641 scopus 로고    scopus 로고
    • + T cells for efficient tumor cell lysis
    • Jenne L, Arrighi J-F, Jonuleit H, et al. Dendritic cells containing apoptotic melanoma cells prime human CD8+ T cells for efcient tumor cell lysis. Cancer Res 2000;60:4446-4452. (Pubitemid 32103624)
    • (2000) Cancer Research , vol.60 , Issue.16 , pp. 4446-4452
    • Jenne, L.1    Arrighi, J.-F.2    Jonuleit, H.3    Saurat, J.-H.4    Hauser, C.5
  • 25
    • 0034672233 scopus 로고    scopus 로고
    • The long pentraxin PTX3 binds to apoptotic cells and regulates their clearance by antigen-presenting dendritic cells
    • Rovere P, Peri G, Fazzini F, et al. The long pentraxin PTX3 binds to apoptotic cells and regulates their clearance by antigen-presenting dendritic cells. Blood 2000;96:4300-4306.
    • (2000) Blood , vol.96 , pp. 4300-4306
    • Rovere, P.1    Peri, G.2    Fazzini, F.3
  • 27
    • 44649170385 scopus 로고    scopus 로고
    • Whole tumor antigen vaccination using dendritic cells: Comparison of RNA electroporation and pulsing with UV-irradiated tumor cells
    • Benencia F, Courreges M, Coukos G. Whole tumor antigen vaccination using dendritic cells: Comparison of RNA electroporation and pulsing with UV-irradiated tumor cells. J Transl Med 2008;6:21-34.
    • (2008) J Transl Med , vol.6 , pp. 21-34
    • Benencia, F.1    Courreges, M.2    Coukos, G.3
  • 28
    • 30944437240 scopus 로고    scopus 로고
    • Preparation of apoptotic tumor cells with replication-incompetent HSV augments the efcacy of dendritic cell vaccines
    • Courreges MC, Benencia F, Conejo-Garcia JR, et al. Preparation of apoptotic tumor cells with replication-incompetent HSV augments the efcacy of dendritic cell vaccines. Cancer Gene Ter 2005;13:182-193.
    • (2005) Cancer Gene ter , vol.13 , pp. 182-193
    • Courreges, M.C.1    Benencia, F.2    Conejo-Garcia, J.R.3
  • 30
    • 0033798213 scopus 로고    scopus 로고
    • Skin tests predict survival after autol-ogous tumor cell vaccination in metastatic melanoma: Experience in 81 patients
    • Baars A, Claessen AME, Van Den Eertwegh AJM, et al. Skin tests predict survival after autol-ogous tumor cell vaccination in metastatic melanoma: Experience in 81 patients. Ann Oncol 2000;11:965-970.
    • (2000) Ann Oncol , vol.11 , pp. 965-970
    • Baars, A.1    Claessen, A.M.E.2    Van Den Eertwegh, A.J.M.3
  • 34
    • 77958183517 scopus 로고    scopus 로고
    • Durable complete response of refractory, progressing metastatic melanoma after treatment with a patient-Specific vaccine
    • Dillman RO, Nanci AA, Williams ST, et al. Durable complete response of refractory, progressing metastatic melanoma after treatment with a patient-Specific vaccine. Cancer Biother Radiopharm 2010;25:553-557.
    • (2010) Cancer Biother Radiopharm , vol.25 , pp. 553-557
    • Dillman, R.O.1    Nanci, A.A.2    Williams, S.T.3
  • 35
    • 0033793249 scopus 로고    scopus 로고
    • Enhanced immunogenicity of aldehyde-bearing antigens: A possible link between innate and adaptive immunity
    • Allison MED, Fearon DT. Enhanced immunogenicity of aldehyde-bearing antigens: A possible link between innate and adaptive immunity. Eur J Immunol 2000;30:2881-2887.
    • (2000) Eur J Immunol , vol.30 , pp. 2881-2887
    • Allison, M.E.D.1    Fearon, D.T.2
  • 36
    • 0026070131 scopus 로고
    • Enhancement of immunogenic properties of oval-bumin as a result of its chlorination
    • Marcinkiewicz J, Chain BM, Olszowska E, et al. Enhancement of immunogenic properties of oval-bumin as a result of its chlorination. Intl J Biochem 1991;23:1393-1395.
    • (1991) Intl J Biochem , vol.23 , pp. 1393-1395
    • Marcinkiewicz, J.1    Chain, B.M.2    Olszowska, E.3
  • 37
    • 0026777691 scopus 로고
    • Enhancement of trinitrophenyl-Specific humoral response to TNP proteins as the result of carrier chlorination
    • Marcinkiewicz J, Olszowska E, Olszowski S, Zgliczynski J. Enhancement of trinitrophenyl-Specific humoral response to TNP proteins as the result of carrier chlorination. Immunology 1992;76:385-388.
    • (1992) Immunology , vol.76 , pp. 385-388
    • Marcinkiewicz, J.1    Olszowska, E.2    Olszowski, S.3    Zgliczynski, J.4
  • 38
    • 0031732062 scopus 로고    scopus 로고
    • Immunological adjuvance of metabolic origin: Oxidative stress, postulated impaired function of thiol proteases and immunogenicity
    • DOI 10.1046/j.1365-3083.1998.00443.x
    • StarkJM. Immunologicaladjuvance of metabolic origin:Oxidative stress, postulatedimpaired function of thiol proteases and immunogenicity. Scand J Immunol 1998;48:475-479. (Pubitemid 28505670)
    • (1998) Scandinavian Journal of Immunology , vol.48 , Issue.5 , pp. 475-479
    • Stark, J.M.1
  • 39
    • 0037072758 scopus 로고    scopus 로고
    • Diferential acquisition of antigenic peptides by Hsp70 and Hsc70 under oxidative conditions
    • Callahan MK, Chaillot D, Jacquin C, et al. Diferential acquisition of antigenic peptides by Hsp70 and Hsc70 under oxidative conditions. J Biol Chem 2002;277:33604-33609.
    • (2002) J Biol Chem , vol.277 , pp. 33604-33609
    • Callahan, M.K.1    Chaillot, D.2    Jacquin, C.3
  • 40
    • 0036911138 scopus 로고    scopus 로고
    • Hydrogen peroxide as second messenger in lymphocyte activation
    • DOI 10.1038/ni1202-1129
    • Reth M. Hydrogen peroxide as second messenger in lymphocyte activation. Nat Immunol 2002;3:1129-1134. (Pubitemid 35469696)
    • (2002) Nature Immunology , vol.3 , Issue.12 , pp. 1129-1134
    • Reth, M.1
  • 41
    • 0344286517 scopus 로고    scopus 로고
    • The role of reactive oxygen species in triggering proliferation and IL-2 secretion in T cells
    • Tatla S, Woodhead V, Foreman JC, Chain BM. The role of reactive oxygen species in triggering proliferation and IL-2 secretion in T cells. Free Rad Biol Med 1999;26:14-24.
    • (1999) Free Rad Biol Med , vol.26 , pp. 14-24
    • Tatla, S.1    Woodhead, V.2    Foreman, J.C.3    Chain, B.M.4
  • 42
    • 51049094007 scopus 로고    scopus 로고
    • Oxidation of ovarian epithelial cancer cells by hypochlorous acid enhances immunogenicity and stimulates T cells that recognize autologous primary tumor
    • Chiang CL, Ledermann JA, Egla A, et al. Oxidation of ovarian epithelial cancer cells by hypochlorous acid enhances immunogenicity and stimulates T cells that recognize autologous primary tumor. Clin Cancer Res 2008;14:4898-4907.
    • (2008) Clin Cancer Res , vol.14 , pp. 4898-4907
    • Chiang, C.L.1    Ledermann, J.A.2    Egla, A.3
  • 43
    • 33746894710 scopus 로고    scopus 로고
    • Hypochlorous acid enhances immunogenicity and uptake of allogeneic ovarian tumor cells by dendritic cells to cross-prime tumor-specific T cells
    • DOI 10.1007/s00262-006-0127-9
    • Chiang C, Ledermann J, Rad AN, Katz D, Chain B. Hypochlorous acid enhances immunogenicity and uptake of allogeneic ovarian tumor cells by dendritic cells to cross-prime tumor-Specific T cells. Cancer Immunol Immunother 2006;55:1384-1395. (Pubitemid 44187670)
    • (2006) Cancer Immunology, Immunotherapy , vol.55 , Issue.11 , pp. 1384-1395
    • Chiang, C.L.-L.1    Ledermann, J.A.2    Rad, A.N.3    Katz, D.R.4    Chain, B.M.5
  • 44
    • 0030854261 scopus 로고    scopus 로고
    • Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein: A mechanism for the generation of highly reactive α-hydroxy and α,β-unsaturated aldehydes by phagocytes at sites of inflammation
    • Anderson MM, Hazen SL, Hsu FF, Heinecke JW. Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein. A mechanism for the generation of highly reactive alpha-hydroxy and alpha,beta-unsaturated aldehydes by phagocytes at sites of infammation. J Clin Invest 1997;99:424-432. (Pubitemid 27414799)
    • (1997) Journal of Clinical Investigation , vol.99 , Issue.3 , pp. 424-432
    • Anderson, M.M.1    Hazen, S.L.2    Hsu, F.F.3    Heinecke, J.W.4
  • 45
    • 0032694683 scopus 로고    scopus 로고
    • The myeloperoxidase system of human phagocytes generates N(ε)- (carboxymethyl)lysine on proteins: A mechanism for producing advanced glycation end products at sites of inflammation
    • Anderson MM, Requena JR, Crowley JR, et al. The myeloperoxidase system of human phagocytes generates Nε-(carboxymethyl)lysine on proteins: A mechanism for producing advanced glycation end products at sites of infammation. J Clin Invest 1999;104:103-113. (Pubitemid 29534350)
    • (1999) Journal of Clinical Investigation , vol.104 , Issue.1 , pp. 103-113
    • Anderson, M.M.1    Requena, J.R.2    Crowley, J.R.3    Thorpe, S.R.4    Heinecke, J.W.5
  • 47
    • 0031762701 scopus 로고    scopus 로고
    • Oxidation of defined antigens allows protein unfolding and increases both proteolytic processing and exposes peptide epitopes which are recognized by specific T cells
    • DOI 10.1046/j.1365-2567.1998.00618.x
    • Carrasco-Maŕn SE, Paz-Miguel J, López-Mato P, et al. Oxidation of defned antigens allows protein unfolding and increases both proteolytic processing and exposes peptide epitopes which are recognized by Specific T cells. Immunology 1998;95:314-321. (Pubitemid 28505685)
    • (1998) Immunology , vol.95 , Issue.3 , pp. 314-321
    • Carrasco-Marin, E.1    Paz-Miguel, J.E.2    Lopez-Mato, P.3    Alvarez-Dominguez, C.4    Leyva-Cobian, F.5
  • 48
    • 0033057848 scopus 로고    scopus 로고
    • Heat-shock proteins, molecular chaperones, and the stress response: Evolutionary and ecological physiology
    • DOI 10.1146/annurev.physiol.61.1.243
    • Feder ME, Hofmann GE. Heat-shock proteins, molecular chaperones, and the stress response: Evolutionary and ecological physiology. Annu Rev Physiol 1999;61:243-282. (Pubitemid 29143171)
    • (1999) Annual Review of Physiology , vol.61 , pp. 243-282
    • Feder, M.E.1    Hofmann, G.E.2
  • 52
    • 0037196444 scopus 로고    scopus 로고
    • Lectin-like oxidized low density lipoprotein receptor-1 (LOX-1) serves as an endothelial receptor for advanced glycation end products (AGE)
    • DOI 10.1016/S0014-5793(01)03325-7, PII S0014579301033257
    • Jono T, Miyazaki A, Nagai R, et al. Lectin-like oxidized low density lipoprotein receptor-1 (LOX-1) serves as an endothelial receptor for advanced glycation end products (AGE). FEBS Lett 2002;511:170-174. (Pubitemid 34127844)
    • (2002) FEBS Letters , vol.511 , Issue.1-3 , pp. 170-174
    • Jono, T.1    Miyazaki, A.2    Nagai, R.3    Sawamura, T.4    Kitamura, T.5    Horiuchi, S.6
  • 54
    • 0035318546 scopus 로고    scopus 로고
    • Identifcation of the human analog of SR-BI and LOX-1 as receptors for hypochlorite-modifed high-density lipoprotein on human umbilical venous endothelial cells
    • Marsche G, Levak-Frank S, Quehenberger O, et al. Identifcation of the human analog of SR-BI and LOX-1 as receptors for hypochlorite-modifed high-density lipoprotein on human umbilical venous endothelial cells. FASEB J 2001;15:1095-1097.
    • (2001) FASEB J , vol.15 , pp. 1095-1097
    • Marsche, G.1    Levak-Frank, S.2    Quehenberger, O.3
  • 56
    • 76249105638 scopus 로고    scopus 로고
    • Hypochlorous acid: A natural adjuvant that facilitates antigen processing, cross-priming, and the induction of adaptive immunity
    • Prokopowicz ZM, Arce F, Biedron R, et al. Hypochlorous acid: A natural adjuvant that facilitates antigen processing, cross-priming, and the induction of adaptive immunity. J Immunol 2010;184:824-835.
    • (2010) J Immunol , vol.184 , pp. 824-835
    • Prokopowicz, Z.M.1    Arce, F.2    Biedron, R.3
  • 57
    • 0346220287 scopus 로고    scopus 로고
    • Class B Scavenger Receptors CD36 and SR-BI Are Receptors for Hypochlorite-modified Low Density Lipoprotein
    • DOI 10.1074/jbc.M308428200
    • Marsche G, Zimmermann R, Horiuchi S, et al. Class B scavenger receptors CD36 and SR-BI are receptors for hypochlorite-modifed low density lipoprotein. J Biol Chem 2003;278:47562-47570. (Pubitemid 37523199)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.48 , pp. 47562-47570
    • Marsche, G.1    Zimmermann, R.2    Horiuchi, S.3    Tandon, N.N.4    Sattler, W.5    Malle, E.6
  • 58
    • 0035918193 scopus 로고    scopus 로고
    • Scavenger receptor Class B Type I-mediated reverse cholesterol transport is inhibited by Advanced End products
    • Ohgami N, Nagai R, Miyazaki A, et al. scavenger receptor Class B Type I-mediated reverse cholesterol transport is inhibited by Advanced End products. J Biol Chem 2001;276:13348-13355.
    • (2001) J Biol Chem , vol.276 , pp. 13348-13355
    • Ohgami, N.1    Nagai, R.2    Miyazaki, A.3
  • 59
    • 20844456664 scopus 로고    scopus 로고
    • GM-CSF gene-transduced tumor vaccines
    • DOI 10.1016/j.ymthe.2005.02.012, PII S1525001605000821
    • Eager R, John N. GM-CSF gene-transduced tumor vaccines. Mol Ter 2005;12:18-27. (Pubitemid 40862352)
    • (2005) Molecular Therapy , vol.12 , Issue.1 , pp. 18-27
    • Eager, R.1    Nemunaitis, J.2
  • 60
    • 33745219416 scopus 로고    scopus 로고
    • Phase I/II trial of an allogeneic cellular immunotherapy in hormone-nä?ve prostate cancer
    • Simons J, Carducci M, Mikhak B, et al. Phase I/II trial of an allogeneic cellular immunotherapy in hormone-nä?ve prostate cancer. Clin Cancer Res 2006;12:3394-3401.
    • (2006) Clin Cancer Res , vol.12 , pp. 3394-3401
    • Simons, J.1    Carducci, M.2    Mikhak, B.3
  • 64
    • 34250223096 scopus 로고    scopus 로고
    • A pilot trial of CTLA-4 blockade with human anti-CTLA-4 in patients with hormone-refractory prostate cancer
    • DOI 10.1158/1078-0432.CCR-06-2318
    • Small E, Tchekmedyian N, Rini B, et al. A pilot trial of CTLA-4 blockade with human anti-CTLA-4 in patients with hormone-refractory prostate cancer. Clin Cancer Res 2007;13:1810-1815. (Pubitemid 46952950)
    • (2007) Clinical Cancer Research , vol.13 , Issue.6 , pp. 1810-1815
    • Small, E.J.1    Tchekmedyian, N.S.2    Rini, B.I.3    Fong, L.4    Lowy, I.5    Allison, J.P.6
  • 65
    • 77951277997 scopus 로고    scopus 로고
    • Current status of immunological therapies for prostate cancer
    • Antonarakis ES,DrakeCG. Current status of immunological therapies for prostate cancer. Curr Opin Urol 2010;20:241-246.
    • (2010) Curr Opin Urol , vol.20 , pp. 241-246
    • Antonarakis, E.S.1    Drake, G.G.2
  • 66
    • 0031836938 scopus 로고    scopus 로고
    • Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression
    • DOI 10.1038/nm0598-581
    • Melcher A, Todryk S, Hardwick N, et al. Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression. Nat Med 1998;4:581-587. (Pubitemid 28237357)
    • (1998) Nature Medicine , vol.4 , Issue.5 , pp. 581-587
    • Melcher, A.1    Todryk, S.2    Hardwick, N.3    Ford, M.4    Jacobson, M.5    Vile, R.G.6
  • 67
    • 0025370889 scopus 로고
    • Active specific immunotherapy with vaccinia colon oncolysate enhances the immunomodulatory and antitumor effects of interleukin-2 and interferon α in a murine hepatic metastasis model
    • DOI 10.1007/BF01740939
    • Arroyo PJ, Bash JA, Wallack MK. Active Specific immunotherapy with vaccinia colon oncolysate enhances the immunomodulatory and antitumor efects of interleukin-2 and interferon α in a murine hepatic metastasis model. Cancer Immunol Immunother 1990;31:305-311. (Pubitemid 20230294)
    • (1990) Cancer Immunology Immunotherapy , vol.31 , Issue.5 , pp. 305-311
    • Arroyo, P.J.1    Bash, J.A.2    Wallack, M.K.3
  • 68
    • 0026268133 scopus 로고
    • Viral oncolysates as human tumor vaccines
    • Sinkovics JG. Viral oncolysates as human tumor vaccines. Int Rev Immunol 1991;7259-7287.
    • (1991) Int Rev Immunol , pp. 7259-7287
    • Sinkovics, J.G.1
  • 69
    • 0028271512 scopus 로고
    • Induction of IgG antibodies directed to a Mr 31,000 melanoma antigen in patients immunized with Vaccinia Virus melanoma oncolysates
    • Berthier-Vergnes O, Portoukalian J, Lefthériotis E, Doré J-F. Induction of IgG antibodies directed to a Mr 31,000 melanoma antigen in patients immunized with Vaccinia Virus melanoma oncolysates. Cancer Res 1994;54:2433-2439.
    • (1994) Cancer Res , vol.54 , pp. 2433-2439
    • Berthier-Vergnes, O.1    Portoukalian, J.2    Lefthériotis, E.3    Doré, J.-F.4
  • 70
    • 13144275236 scopus 로고    scopus 로고
    • Surgical adjuvant active Specific immunotherapy for patients with stage III melanoma: The fnal analysis of data from a phase III, randomized, double-blind, multicenter vaccinia melanoma oncolysate trial
    • Marc KW, Muthukumaran S, Charles MB, et al. Surgical adjuvant active Specific immunotherapy for patients with stage III melanoma: The fnal analysis of data from a phase III, randomized, double-blind, multicenter vaccinia melanoma oncolysate trial. J Am Coll Surg 1998;187:69-79.
    • (1998) J Am Coll Surg , vol.187 , pp. 69-79
    • Marc, K.W.1    Muthukumaran, S.2    Charles, M.B.3
  • 72
    • 0025297295 scopus 로고
    • Immunological effects of tumor vaccines: II. T cell responses directed against cellular antigens in the viral oncolysates
    • Ioannides C, Platsoucas C, Freedman R. Immunological efects of tumor vaccines: II. T cell responses directed against cellular antigens in the viral oncolysates. In Vivo 1990;4:17-24. (Pubitemid 20180056)
    • (1990) In Vivo , vol.4 , Issue.1 , pp. 17-24
    • Ioannides, C.G.1    Platsoucas, C.D.2    Freedman, R.S.3
  • 74
    • 18144363557 scopus 로고    scopus 로고
    • Clinical trials of antitumor vaccination with an autologous tumor cell vaccine modified by virus infection: Improvement of patient survival based on improved antitumor immune memory
    • DOI 10.1007/s00262-004-0602-0
    • Schirrmacher V. Clinical trials of antitumor vaccination with an autologous tumor cell vaccine modifedbyvirus infection: Improvementof patient survival based on improved antitumor immune memory. Cancer Immunol Immunother 2005;54:587-598. (Pubitemid 40613037)
    • (2005) Cancer Immunology, Immunotherapy , vol.54 , Issue.6 , pp. 587-598
    • Schirrmacher, V.1
  • 76
    • 0033875563 scopus 로고    scopus 로고
    • Oncolytic herpes simplex virus-1 lacking ICP34.5 induces p53-independent death and is efficacious against chemotherapy-resistant ovarian cancer
    • Coukos G, Makrigiannakis A, Kang EH, et al. Molnar-Kimber oncolytic Herpes Simplex Virus-1 lacking ICP34.5 induces p53-independent death and is efcacious against chemotherapy-resistant ovarian cancer. Clin Cancer Res 2000;6:3342-3353. (Pubitemid 30637766)
    • (2000) Clinical Cancer Research , vol.6 , Issue.8 , pp. 3342-3353
    • Coukos, G.1    Makrigiannakis, A.2    Kang, E.H.3    Rubin, S.C.4    Albelda, S.M.5    Molnar-Kimber, K.L.6
  • 77
    • 0032758642 scopus 로고    scopus 로고
    • Induction and prevention of apoptosis in human HEp-2 cells by Herpes Simplex Virus Type 1
    • Aubert M, O'Toole J, Blaho JA. Induction and prevention of apoptosis in human HEp-2 cells by Herpes Simplex Virus Type 1. J Virol 1999;73:10359-10370.
    • (1999) J Virol , vol.73 , pp. 10359-10370
    • Aubert, M.1    O'Toole, J.2    Blaho, J.A.3
  • 78
    • 0032584081 scopus 로고    scopus 로고
    • Herpes simplex virus 1 induces and blocks apoptosis at multiple steps during infection and protects cells from exogenous inducers in a cell-type-dependent manner
    • Galvan V, Roizman B. Herpes simplex virus 1 induces and blocks apoptosis at multiple steps during infection and protects cells from exogenous inducers in a cell-type-dependent manner. Proc Natl Acad Sci USA 1998;95:3931-3936.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 3931-3936
    • Galvan, V.1    Roizman, B.2
  • 79
    • 0031957982 scopus 로고    scopus 로고
    • In vivo production of cytokines and β (C-C) chemokines in human recurrent herpes simplex lesions - Do herpes simplex virus - Infected keratinocytes contribute to their production?
    • Miklos Z, Danis VA, Adams S, et al. In vivo production of cytokines and β (C-C) chemokines in human recurrent Herpes Simplex lesions-do Herpes Simplex Virus-infected keratinocytes contribute to their production? J Infect Dis 1998;177:827-838. (Pubitemid 28155133)
    • (1998) Journal of Infectious Diseases , vol.177 , Issue.4 , pp. 827-838
    • Mikloska, Z.1    Danis, V.A.2    Adams, S.3    Lloyd, A.R.4    Adrian, D.L.5    Cunningham, A.L.6
  • 80
    • 84934437077 scopus 로고    scopus 로고
    • Biological therapy with oncolytic Herpesvirus
    • Coukos G, Berchuck A, Ozols R, eds. New York: Springer
    • Benencia F, Coukos G. Biological therapy with oncolytic Herpesvirus. In: Coukos G, Berchuck A, Ozols R, eds. Ovarian Cancer. Vol. 622: New York: Springer; 2008. 221-233 pp.
    • (2008) Ovarian Cancer , vol.622 , pp. 221-233
    • Benencia, F.1    Coukos, G.2
  • 81
    • 49749109913 scopus 로고    scopus 로고
    • Herpes virus oncolytic therapy reverses tumor immune dysfunction and facilitates tumor antigen presentation
    • Benencia F, Courrèges M, Fraser N, Coukos G. Herpes virus oncolytic therapy reverses tumor immune dysfunction and facilitates tumor antigen presentation. Cancer Biol Ter 2008;7:1194-1205.
    • (2008) Cancer Biol ter , vol.7 , pp. 1194-1205
    • Benencia, F.1    Courrèges, M.2    Fraser, N.3    Coukos, G.4
  • 82
    • 0031950268 scopus 로고    scopus 로고
    • Inhibition of major histocompatibility complex class I antigen presentation in pig and primate cells by herpes simplex virus type 1 and 2 ICP47
    • Jugovic P, Hill AM, Tomazin R, et al. Inhibition of major histocompatibility complex Class I antigen presentation in pig and primate cells by Herpes Simplex Virus Type 1 and 2 ICP47. J Virol 1998;72:5076-5084. (Pubitemid 28215688)
    • (1998) Journal of Virology , vol.72 , Issue.6 , pp. 5076-5084
    • Jugovic, P.1    Hill, A.M.2    Tomazin, R.3    Ploegh, H.4    Johnson, D.C.5
  • 83
    • 0030958819 scopus 로고    scopus 로고
    • The herpes simplex virus immediate-early protein ICP0 affects transcription from the viral genome and infected-cell survival in the absence of ICP4 and ICP27
    • Samaniego L, Wu N, DeLuca N. The herpes simplex virus immediate-early protein ICP0 afects transcription from the viral genome and infected-cell survival in the absence of ICP4 and ICP27. J Virol 1997;71:4614-4625. (Pubitemid 27204154)
    • (1997) Journal of Virology , vol.71 , Issue.6 , pp. 4614-4625
    • Samaniego, L.A.1    Wu, N.2    DeLuca, N.A.3
  • 86
    • 0035889708 scopus 로고    scopus 로고
    • Treatment of metastatic melanomawith autologous, hapten-modifed melanoma vaccine: Regression of pulmonary metastases
    • Berd D, Sato T, Cohn H, et al. Treatment of metastatic melanomawith autologous, hapten-modifed melanoma vaccine: Regression of pulmonary metastases. Int J Cancer 2001;94:531-539.
    • (2001) Int J Cancer , vol.94 , pp. 531-539
    • Berd, D.1    Sato, T.2    Cohn, H.3
  • 87
    • 33947629255 scopus 로고    scopus 로고
    • Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors
    • DOI 10.1016/j.smim.2006.12.002, PII S1044532306001229, TLR-Mediated Innate Immune Recognition
    • Miyake K. Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors. Semin Immunol 2007;19:3-10. (Pubitemid 46498750)
    • (2007) Seminars in Immunology , vol.19 , Issue.1 , pp. 3-10
    • Miyake, K.1
  • 88
    • 5444234216 scopus 로고    scopus 로고
    • The interface between innate and adaptive immunity
    • DOI 10.1038/ni1004-971
    • Hoebe K, Janssen E, Beutler B. The interface between innate and adaptive immunity. Nat Immunol 2004;5:971-974. (Pubitemid 41057712)
    • (2004) Nature Immunology , vol.5 , Issue.10 , pp. 971-974
    • Hoebe, K.1    Janssen, E.2    Beutler, B.3
  • 89
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol 2004;4:499-511. (Pubitemid 38931765)
    • (2004) Nature Reviews Immunology , vol.4 , Issue.7 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 90
    • 42949160629 scopus 로고    scopus 로고
    • The potency of the adjuvant, CpG oligos, is enhanced by encapsulation in PLG microparticles
    • Malyala P, Chesko J, Ugozzoli M, et al. The potency of the adjuvant, CpG oligos, is enhanced by encapsulation in PLG microparticles. J Pharm Sci 2008;97:1155-1164.
    • (2008) J Pharm Sci , vol.97 , pp. 1155-1164
    • Malyala, P.1    Chesko, J.2    Ugozzoli, M.3
  • 92
    • 0037056053 scopus 로고    scopus 로고
    • Synergistic adjuvant activity of immunostimulatory DNA and oil/water emulsions for immunization with HIV p55 gag antigen
    • DOI 10.1016/S0264-410X(02)00272-4, PII S0264410X02002724
    • O'Hagan DT, Singh M, Kazzaz J, et al. Synergistic adjuvant activity of immunostimulatory DNA and oil/water emulsions for immunization with HIV p55 gag antigen. Vaccine 2002;20:3389-3398. (Pubitemid 35245822)
    • (2002) Vaccine , vol.20 , Issue.27-28 , pp. 3389-3398
    • O'Hagan, D.T.1    Singh, M.2    Kazzaz, J.3    Ugozzoli, M.4    Briones, M.5    Donnelly, J.6    Ott, G.7
  • 93
    • 37849039132 scopus 로고    scopus 로고
    • Combination adjuvants for the induction of potent, long-lasting antibody and T-cell responses to infuenza vaccine in mice
    • Wack A, Baudner BC, Hilbert AK, et al. Combination adjuvants for the induction of potent, long-lasting antibody and T-cell responses to infuenza vaccine in mice. Vaccine 2008;26:552-561.
    • (2008) Vaccine , vol.26 , pp. 552-561
    • Wack, A.1    Baudner, B.C.2    Hilbert, A.K.3
  • 94
    • 35349028297 scopus 로고    scopus 로고
    • GlaxoSmithKline Adjuvant Systems in vaccines: Concepts, achievements and perspectives
    • DOI 10.1586/14760584.6.5.723
    • Garçon N, Chomez P, Van Mechelen M. GlaxoSmithKline adjuvant systems in vaccines: Concepts, achievements and perspectives. Expert Rev Vaccines 2007;6:723-739. (Pubitemid 47607848)
    • (2007) Expert Review of Vaccines , vol.6 , Issue.5 , pp. 723-739
    • Garcon, N.1    Chomez, P.2    Van Mechelen, M.3
  • 95
    • 34547612220 scopus 로고    scopus 로고
    • Thirty years of BCG immunotherapy for non-muscle invasive bladder cancer: A success story with room for improvement
    • DOI 10.1016/j.biopha.2007.05.004, PII S0753332207001060
    • Brandau S, Suttmann H. Tirty years of BCG immunotherapy for non-muscle invasive bladder cancer: A success story with room for improvement. Biomed Pharmacother 2007;61:299-305. (Pubitemid 47189735)
    • (2007) Biomedicine and Pharmacotherapy , vol.61 , Issue.6 , pp. 299-305
    • Brandau, S.1    Suttmann, H.2
  • 96
    • 0043267978 scopus 로고    scopus 로고
    • Simultaneous blocking of human toll-like receptors 2 and 4 suppresses myeloid dendritic cell activation induced by Mycobacterium bovis bacillus Calmette-Guérin peptidoglycan
    • DOI 10.1128/IAI.71.8.4238-4249.2003
    • Uehori J, Matsumoto M, Tsuji S, et al. Simultaneous blocking of human toll-like receptors 2 and 4 suppresses myeloid dendritic cell activation induced by Mycobacterium bovis Bacillus Calmette-Guerin Peptidoglycan. Infect Immun 2003;71:4238-4249. (Pubitemid 36919886)
    • (2003) Infection and Immunity , vol.71 , Issue.8 , pp. 4238-4249
    • Uehori, J.1    Matsumoto, M.2    Tsuji, S.3    Akazawa, T.4    Takeuchi, O.5    Akira, S.6    Kawata, T.7    Azuma, I.8    Toyoshima, K.9    Seya, T.10
  • 97
    • 0742321971 scopus 로고    scopus 로고
    • Results of clinical trials with an allogeneic melanoma tumor cell lysate vaccine: Melacine®
    • DOI 10.1016/j.semcancer.2003.09.004
    • Sondak VK, Sosman JA. Results of clinical trials with an allogeneic melanoma tumor cell lysate vaccine: Melacine®. Semin Cancer Biol 2003;13:409-415. (Pubitemid 38156132)
    • (2003) Seminars in Cancer Biology , vol.13 , Issue.6 , pp. 409-415
    • Sondak, V.K.1    Sosman, J.A.2
  • 99
    • 0018755293 scopus 로고
    • Randomized study of chemoimmunotherapy for advanced ovarian carcinoma: A preliminary report of a Southwest Oncology Group study
    • Alberts DS, Moon TE, Stephens RA. Randomized study of chemoimmunotherapy for advanced ovarian carcinoma: A preliminary report of a Southwest Oncology Group study. Cancer Treat Rep 1979;63:325-331. (Pubitemid 9151522)
    • (1979) Cancer Treatment Reports , vol.63 , Issue.2 , pp. 325-331
    • Alberts, D.S.1    Moon, T.E.2    Stephens, R.A.3
  • 100
    • 0024789709 scopus 로고
    • Second-look laparotomy in the patient with minimal residual stage III ovarian cancer (a Gynecologic Oncology Group study)
    • DOI 10.1016/0090-8258(89)90083-8
    • Creasman WT, Gall S, Bundy BN, et al. Second-look laparotomy in the patient with minimal residual stage III ovarian cancer (a Gynecologic Oncology Group study). Gynecol Oncol 1989;35:378-382. (Pubitemid 20025906)
    • (1989) Gynecologic Oncology , vol.35 , Issue.3 , pp. 378-382
    • Creasman, W.T.1    Gall, S.2    Bundy, B.N.3    Beecham, J.4    Mortel, R.5    Homesley, H.D.6
  • 101
    • 0344416987 scopus 로고    scopus 로고
    • Mycoplasmal lipopeptide MALP-2 induces the chemoattractant proteins macrophage inflammatory protein 1α (MIP-1α, monocyte chemoattractant protein 1, and MIP-2 and promotes leukocyte infiltration in mice
    • Deiters U, Muhlradt PF. Mycoplasmal lipopeptide MALP-2 induces the chemoattractant proteins macrophage infammatory protein 1 alpha (MIP-1alpha), monocyte chemoattractant protein 1, and MIP-2 and promotes leukocyte infltration in mice. Infect Immun 1999;67:3390-3398. (Pubitemid 29291507)
    • (1999) Infection and Immunity , vol.67 , Issue.7 , pp. 3390-3398
    • Deiters, U.1    Muhlradt, P.F.2
  • 102
    • 0345580664 scopus 로고    scopus 로고
    • Induction of cytokines and chemokines in human monocytes by mycoplasma fermentans-derived lipoprotein MALP-2
    • Kaufmann A, Muhlradt PF, Gemsa D, Sprenger H. Induction of cytokines and chemokines in human monocytes by mycoplasma fermentans-derived lipoprotein MALP-2. Infect Immun 1999;67:6303-6308.
    • (1999) Infect Immun , vol.67 , pp. 6303-6308
    • Kaufmann, A.1    Muhlradt, P.F.2    Gemsa, D.3    Sprenger, H.4
  • 105
    • 34548316162 scopus 로고    scopus 로고
    • Intratumoural injection of the toll-like receptor-2/6 agonist 'macrophage-activating lipopeptide-2' in patients with pancreatic carcinoma: A phase I/II trial
    • DOI 10.1038/sj.bjc.6603903, PII 6603903
    • Schmidt J, Welsch T, Jager D, et al. Intratumoural injection of the toll-like receptor-2/6 agonist 'macrophage-activating lipopeptide-2' in patients with pancreatic carcinoma: A phase I/II trial. Br J Cancer 2007;97:598-604. (Pubitemid 47339882)
    • (2007) British Journal of Cancer , vol.97 , Issue.5 , pp. 598-604
    • Schmidt, J.1    Welsch, T.2    Jager, D.3    Muhlradt, P.F.4    Buchler, M.W.5    Marten, A.6
  • 106
    • 0033168630 scopus 로고    scopus 로고
    • Polyriboinosinic polyribocytidylic acid (poly(I:C)) induces stable maturation of functionally active human dendritic cells
    • Verdijk RM, Mutis T, Esendam B, et al. Polyriboinosinic Polyribocytidylic Acid (Poly(I:C)) induces stable maturation of functionally active human dendritic cells. J Immunol 1999;163:57-61. (Pubitemid 29295824)
    • (1999) Journal of Immunology , vol.163 , Issue.1 , pp. 57-61
    • Verdijk, R.M.1    Mutis, T.2    Esendam, B.3    Kamp, J.4    Melief, C.J.M.5    Brand, A.6    Goulmy, E.7
  • 107
    • 77953502765 scopus 로고    scopus 로고
    • Human CD141+ (BDCA-3) +dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens
    • Jongbloed SL, Kassianos AJ, McDonald KJ, et al. Human CD141+ (BDCA-3) +dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens. J Exp Med 2010;207:1247-1260.
    • (2010) J Exp Med , vol.207 , pp. 1247-1260
    • Jongbloed, S.L.1    Kassianos, A.J.2    McDonald, K.J.3
  • 108
    • 0017108014 scopus 로고
    • A phase I-II trial of multiple-dose polyriboinosic-polyribocytidylic acid in patieonts with leukemia or solid tumors
    • Robinson R, DeVita V, Levy H, et al. A phase I-II trial of multiple-dose polyriboinosic-polyribocytidylic acid in patieonts with leukemia or solid tumors. J Natl Cancer Inst 1976;57:599-603.
    • (1976) J Natl Cancer Inst , vol.57 , pp. 599-603
    • Robinson, R.1    Devita, V.2    Levy, H.3
  • 109
    • 9444284910 scopus 로고    scopus 로고
    • Results of a double-blind placebo-controlled study of the double-stranded RNA drug poly I:polyC12U in the treatment of HIV infection
    • Tompson KA, Strayer DR, Salvato PD, et al. Results of a double-blind placebo-controlled study of the double-stranded RNA drug polyI:polyC12U in the treatment of HIV infection. Eur J Clin Microbiol Infect Dis 1996;15:580-587.
    • (1996) Eur J Clin Microbiol Infect Dis , vol.15 , pp. 580-587
    • Tompson, K.A.1    Strayer, D.R.2    Salvato, P.D.3
  • 110
    • 0028009931 scopus 로고
    • A controlled clinical trial with a specifcally confgured RNA drug, Poly(I). Poly(C12U), in chronic fatigue syndrome
    • Strayer DR, Carter WA, BrodskyI, et al. A controlled clinical trial with a specifcally confgured RNA drug, Poly(I). Poly(C12U), in chronic fatigue syndrome. Clin Infect Dis 1994;18:S88-S95.
    • (1994) Clin Infect Dis , vol.18
    • Strayer, D.R.1    Brodskyi, C.W.2
  • 111
    • 56949108633 scopus 로고    scopus 로고
    • A clinical grade poly I:C-analogue (Ampligen®) promotes optimal DC maturation and T1-type T cell responses of healthy donors and cancer patients in vitro
    • Navabi H, Jasani B, Reece A, et al. A clinical grade poly I:C-analogue (Ampligen®) promotes optimal DC maturation and T1-type T cell responses of healthy donors and cancer patients in vitro. Vaccine 2009;27:107-115.
    • (2009) Vaccine , vol.27 , pp. 107-115
    • Navabi, H.1    Jasani, B.2    Reece, A.3
  • 114
    • 0017639328 scopus 로고
    • Pharmacologic effects of polyinosinic-polycytidylic acid in man
    • Freeman A, Al-Bussam N, O'Malley J, et al. Pharmacologic effects of polyinosinic-polycytidylic acid in man. J Med Virol 1977;1:79-93.
    • (1977) J Med Virol , vol.1 , pp. 79-93
    • Freeman, A.1    Al-Bussam, N.2    O'Malley, J.3
  • 115
    • 33745404635 scopus 로고    scopus 로고
    • Nasal immunization with anthrax protective antigen protein adjuvanted with polyriboinosinic-polyribocytidylic acid induced strong mucosal and systemic immunities
    • DOI 10.1007/s11095-006-0206-9
    • Sloat B, Cui Z. Nasal Immunization with anthrax protective antigen protein adjuvanted with polyriboinosinic-polyribocytidylic acid induced strong mucosal and systemic immunities. Pharma Res 2006;23:1217-1226. (Pubitemid 43946144)
    • (2006) Pharmaceutical Research , vol.23 , Issue.6 , pp. 1217-1226
    • Sloat, B.R.1    Cui, Z.2
  • 117
    • 40949134086 scopus 로고    scopus 로고
    • TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β
    • DOI 10.1038/ni1569, PII NI1569
    • Kagan JC, Su T, Horng T, et al. TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-. Nat Immunol 2008;9:361-368. (Pubitemid 351405105)
    • (2008) Nature Immunology , vol.9 , Issue.4 , pp. 361-368
    • Kagan, J.C.1    Su, T.2    Horng, T.3    Chow, A.4    Akira, S.5    Medzhitov, R.6
  • 118
    • 34249677845 scopus 로고    scopus 로고
    • Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists
    • DOI 10.1038/nm1589, PII NM1589
    • Kanzler H, Barrat FJ, Hessel EM, Cofman RL. Terapeutic targeting of innate immunity with Tolllike receptor agonists and antagonists. Nat Med 2007;13:552-559. (Pubitemid 46830615)
    • (2007) Nature Medicine , vol.13 , Issue.5 , pp. 552-559
    • Kanzler, H.1    Barrat, F.J.2    Hessel, E.M.3    Coffman, R.L.4
  • 119
    • 34250854079 scopus 로고    scopus 로고
    • The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4
    • DOI 10.1126/science.1138963
    • Mata-Haro V, Cekic C, Martin M, et al. The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4. Science 2007;316:1628-1632. (Pubitemid 46982038)
    • (2007) Science , vol.316 , Issue.5831 , pp. 1628-1632
    • Mata-Haro, V.1    Cekic, C.2    Martin, M.3    Chilton, P.M.4    Casella, C.R.5    Mitchell, T.C.6
  • 120
    • 0032755036 scopus 로고    scopus 로고
    • Monophosphoryl lipid A (MPL) formulations for the next generation of vaccines
    • DOI 10.1006/meth.1999.0834
    • Baldridge JR, Crane RT. Monophosphoryl lipid A (MPL) formulations for the next generation of vaccines. Methods 1999;19:103-107. (Pubitemid 29497759)
    • (1999) Methods: A Companion to Methods in Enzymology , vol.19 , Issue.1 , pp. 103-107
    • Baldridge, J.R.1    Crane, R.T.2
  • 121
    • 0037407849 scopus 로고    scopus 로고
    • Role of innate immune factors in the adjuvant activity of monophosphoryl lipid A
    • DOI 10.1128/IAI.71.5.2498-2507.2003
    • Martin M, Michalek SM, Katz J. Role of innate immune factors in the adjuvant activity of monophosphoryl lipid A. Infect Immun 2003;71:2498-2507. (Pubitemid 36519862)
    • (2003) Infection and Immunity , vol.71 , Issue.5 , pp. 2498-2507
    • Martin, M.1    Michalek, S.M.2    Katz, J.3
  • 122
    • 77953231072 scopus 로고    scopus 로고
    • Monophosphoryl lipid A plus IFN-gamma maturation of dendritic cells induces antigen-Specific CD8+ cytotoxic T cells with high cytolytic potential
    • Ten Brinke A, Van Schijndel G, Visser R, et al. Monophosphoryl lipid A plus IFN-gamma maturation of dendritic cells induces antigen-Specific CD8+ cytotoxic T cells with high cytolytic potential. Cancer Immunol Immunother 2010; 59: 1185-1195.
    • (2010) Cancer Immunol Immunother , vol.59 , pp. 1185-1195
    • Ten Brinke, A.1    Van Schijndel, G.2    Visser, R.3
  • 124
    • 50649093779 scopus 로고    scopus 로고
    • The use of TLR7 and TLR8 ligands for the enhancement of cancer immunotherapy
    • Smits EL, Ponsaerts P, Berneman ZN, Van Tendeloo VFI. The use of TLR7 and TLR8 ligands for the enhancement of cancer immunotherapy. Oncologist 2008;13:859-875.
    • (2008) Oncologist , vol.13 , pp. 859-875
    • Smits, E.L.1    Ponsaerts, P.2    Berneman, Z.N.3    Van Tendeloo, V.F.I.4
  • 125
    • 48249107883 scopus 로고    scopus 로고
    • Clinical investigations of Toll-like receptor agonists
    • Meyer T, Stockfeth E. Clinical investigations of Toll-like receptor agonists. Expert Opin Investig Drugs 2008;17:1051-1065.
    • (2008) Expert Opin Investig Drugs , vol.17 , pp. 1051-1065
    • Meyer, T.1    Stockfeth, E.2
  • 126
    • 37848999304 scopus 로고    scopus 로고
    • TLR7 and TLR8 as targets in cancer therapy
    • Schon MP, Schon M. TLR7 and TLR8 as targets in cancer therapy. Oncogene 2008;27:190-199.
    • (2008) Oncogene , vol.27 , pp. 190-199
    • Schon, M.P.1    Schon, M.2
  • 127
    • 77957659880 scopus 로고    scopus 로고
    • Toll-like receptor-7 agonist administered subcutaneously in a prolonged dosing schedule in heavily pretreated recurrent breast, ovarian, and cervix cancers
    • Geller M, Cooley S, Argenta P, et al. Toll-like receptor-7 agonist administered subcutaneously in a prolonged dosing schedule in heavily pretreated recurrent breast, ovarian, and cervix cancers. Cancer Immunol Immunother 2010;59:1877-1884.
    • (2010) Cancer Immunol Immunother , vol.59 , pp. 1877-1884
    • Geller, M.1    Cooley, S.2    Argenta, P.3
  • 130
    • 34248169629 scopus 로고    scopus 로고
    • Development of TLR9 agonists for cancer therapy
    • DOI 10.1172/JCI31414
    • KriegAM. Development of TLR9 agonists for cancer therapy. J Clin Invest 2007;117:1184-1194. (Pubitemid 46718403)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.5 , pp. 1184-1194
    • Krieg, A.M.1
  • 132
    • 74349104485 scopus 로고    scopus 로고
    • Ascites regression and survival increase in mice bearing advanced-stage human ovarian carcinomas and repeatedly treated intraperitoneally with CpG-ODN
    • De Cesare M, Sfondrini L, Campiglio M, et al. Ascites regression and survival increase in mice bearing advanced-stage human ovarian carcinomas and repeatedly treated intraperitoneally with CpG-ODN. J Immunother 2010;33:8-15.
    • (2010) J Immunother , vol.33 , pp. 8-15
    • De Cesare, M.1    Sfondrini, L.2    Campiglio, M.3
  • 133
    • 53049108931 scopus 로고    scopus 로고
    • Eradication of ovarian tumor xenografts by locoregional administration of targeted immunotherapy
    • De Cesare M, Calcaterra C, Pratesi G, et al. Eradication of ovarian tumor xenografts by locoregional administration of targeted immunotherapy. Clin Cancer Res 2008;14:5512-5518.
    • (2008) Clin Cancer Res , vol.14 , pp. 5512-5518
    • De Cesare, M.1    Calcaterra, C.2    Pratesi, G.3
  • 134
    • 64049103406 scopus 로고    scopus 로고
    • Treatment with LL-37 peptide enhances antitumor effects induced by CpG oligodeoxynucleotides against ovarian cancer
    • Chuang C-M, Monie A, Wu A, et al. Treatment with LL-37 peptide enhances antitumor effects induced by CpG oligodeoxynucleotides against ovarian cancer. Human Gene Ter 2009;20:303-313.
    • (2009) Human Gene ter , vol.20 , pp. 303-313
    • Chuang, C.-M.1    Monie, A.2    Wu, A.3
  • 135
    • 78650988917 scopus 로고    scopus 로고
    • A CpG-loaded tumor cell vaccine induces antitumor CD4+ T cells that are efective in adoptive therapy for large and established tumors
    • Goldstein MJ, Varghese B, Brody JD, et al. A CpG-loaded tumor cell vaccine induces antitumor CD4+ T cells that are efective in adoptive therapy for large and established tumors. Blood 2011;117:118-127.
    • (2011) Blood , vol.117 , pp. 118-127
    • Goldstein, M.J.1    Varghese, B.2    Brody, J.D.3
  • 137
    • 4143131229 scopus 로고    scopus 로고
    • Synergistic activation of innate immunity by double-stranded RNA and CpG DNA promotes eahanced antitumor activity
    • DOI 10.1158/0008-5472.CAN-04-0063
    • Whitmore MM, DeVeer MJ, Edling A, et al. Synergistic activation of innate immunity by double-stranded RNA and CpG DNA promotes enhanced antitumor activity. Cancer Res 2004;64:5850-5860. (Pubitemid 39095586)
    • (2004) Cancer Research , vol.64 , Issue.16 , pp. 5850-5860
    • Whitmore, M.M.1    DeVeer, M.J.2    Edling, A.3    Oates, R.K.4    Simons, B.5    Lindner, D.6    Williams, B.R.G.7
  • 138
    • 20044388097 scopus 로고    scopus 로고
    • Montanide® ISA 720 vaccines: Quality control of emulsions, stability of formulated antigens, and comparative immunogenicity of vaccine formulations
    • Miles AP, McClellanHA, RauschKM, et al. Montanide® ISA 720 vaccines: Quality control of emulsions, stability of formulated antigens, and comparative immunogenicity of vaccine formulations. Vaccine 2005;23:2530-2539.
    • (2005) Vaccine , vol.23 , pp. 2530-2539
    • Miles, A.P.1    McClellan, H.A.2    Rausch, K.M.3
  • 139
    • 0031081785 scopus 로고    scopus 로고
    • Phase I trial in humans of an oil-based adjuvant SEPPIC MONTANIDE ISA 720
    • DOI 10.1016/S0264-410X(96)00150-8, PII S0264410X96001508
    • Lawrence GW, Saul A, Giddy AJ, et al. Phase I trial in humans of an oil-based adjuvant SEPPIC MONTANIDE ISA 720. Vaccine 1997;15:176-178. (Pubitemid 27091248)
    • (1997) Vaccine , vol.15 , Issue.2 , pp. 176-178
    • Lawrence, G.W.1    Saul, A.2    Giddy, A.J.3    Kemp, R.4    Pye, P.5
  • 141
    • 0028887329 scopus 로고
    • Induction of protective cytotoxic T cells to murine cytomegalovirus by using a nonapeptide and a human-compatible adjuvant (Montanide ISA 720)
    • Scalzo A, Elliott S, Cox J, et al. Induction of protective cytotoxic T cells to murine cytomegalovirus by using a nonapeptide and a human-compatible adjuvant (Montanide ISA 720). J Virol 1995;69:1306-1309.
    • (1995) J Virol , vol.69 , pp. 1306-1309
    • Scalzo, A.1    Elliott, S.2    Cox, J.3
  • 151
    • 52049088540 scopus 로고    scopus 로고
    • Safety and immunogenicity study of NY-ESO-1b pep-tide and Montanide ISA-51 vaccination of patients with epithelial ovarian cancer in high-risk frst remission
    • Diefenbach CSM, Gnjatic S, Sabbatini P, et al. Safety and immunogenicity study of NY-ESO-1b pep-tide and Montanide ISA-51 vaccination of patients with epithelial ovarian cancer in high-risk frst remission. Clin Cancer Res 2008;14:2740-2748.
    • (2008) Clin Cancer Res , vol.14 , pp. 2740-2748
    • Diefenbach, C.S.M.1    Gnjatic, S.2    Sabbatini, P.3
  • 153
    • 70249141312 scopus 로고    scopus 로고
    • Immunization with a P53 synthetic long peptide vaccine induces P53-Specific immune responses in ovarian cancer patients, a phase II trial
    • Lefers N, Lambeck AJA, Gooden MJM, et al. Immunization with a P53 synthetic long peptide vaccine induces P53-Specific immune responses in ovarian cancer patients, a phase II trial. IntJCancer 2009;125:2104-2113.
    • (2009) IntJCancer , vol.125 , pp. 2104-2113
    • Lefers, N.1    Lambeck, A.J.A.2    Gooden, M.J.M.3
  • 154
    • 45749111446 scopus 로고    scopus 로고
    • Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
    • DOI 10.1038/nature06939, PII NATURE06939
    • Eisenbarth SC, Colegio OR, O'Connor W, et al. Crucial role for the Nalp3 infammasome in the im-munostimulatory properties of aluminium adjuvants. Nature 2008;453:1122-1126. (Pubitemid 351871731)
    • (2008) Nature , vol.453 , Issue.7198 , pp. 1122-1126
    • Eisenbarth, S.C.1    Colegio, O.R.2    O'Connor Jr., W.3    Sutterwala, F.S.4    Flavell, R.A.5
  • 155
    • 35348968868 scopus 로고    scopus 로고
    • Relationship between physical and chemical properties of aluminum-containing adjuvants and immunopotentiation
    • DOI 10.1586/14760584.6.5.685
    • Hem SL, HogenEsch H. Relationship between physical and chemical properties of aluminum-containing adjuvants and immunopotentiation. Expert Rev Vaccines 2007;6:685-698. (Pubitemid 47607846)
    • (2007) Expert Review of Vaccines , vol.6 , Issue.5 , pp. 685-698
    • Hem, S.L.1    Hogenesch, H.2
  • 156
    • 13444292001 scopus 로고    scopus 로고
    • Role of aluminum-containing adjuvants in antigen internalization by dendritic cells in vitro
    • DOI 10.1016/j.vaccine.2004.07.050
    • Morefeld GL, Sokolovska A, Jiang D, et al. Role of aluminum-containing adjuvants in antigen in-ternalization by dendritic cells in vitro. Vaccine 2005;23:1588-1595. (Pubitemid 40203396)
    • (2005) Vaccine , vol.23 , Issue.13 , pp. 1588-1595
    • Morefield, G.L.1    Sokolovska, A.2    Jiang, D.3    Hogenesch, H.4    Robinson, J.P.5    Hem, S.L.6
  • 157
    • 0020398349 scopus 로고
    • Histopathological studies of reactions in mice injected with aluminum-adsorbed tetanus toxoid
    • Goto N, Akama K. Histopathological studies of reactions in mice injected with aluminum-adsorbed tetanus toxoid. Microbiol Immunol 1982;26:1121-1132. (Pubitemid 13146183)
    • (1982) Microbiology and Immunology , vol.26 , Issue.12 , pp. 1121-1132
    • Goto, N.1    Akama, K.2
  • 158
    • 0030921599 scopus 로고    scopus 로고
    • Local tissue irritating effects and adjuvant activities of calcium phosphate and aluminium hydroxide with different physical properties
    • DOI 10.1016/S0264-410X(97)00054-6, PII S0264410X97000546
    • Goto N, Kato H, Maeyama J, et al. Local tissue irritating effects and adjuvant activities of calcium phosphate and aluminium hydroxide with diferent physical properties. Vaccine 1997;15:1364-1371. (Pubitemid 27397815)
    • (1997) Vaccine , vol.15 , Issue.12-13 , pp. 1364-1371
    • Goto, N.1    Kato, H.2    Maeyama, J.-I.3    Shibano, M.4    Saito, T.5    Yamaguchi, J.6    Yoshihara, S.7
  • 161
    • 0038330442 scopus 로고    scopus 로고
    • MF59-adjuvanted vaccines: Increased immunogenicity with an optimal safety profile
    • DOI 10.1586/14760584.2.2.197
    • Podda A, Del Giudice G. MF59-adjuvanted vaccines: Increased immunogenicity with an optimal safety profle. Expert Rev Vaccines 2003;2:197-204. (Pubitemid 36559925)
    • (2003) Expert Review of Vaccines , vol.2 , Issue.2 , pp. 197-204
    • Podda, A.1    Del Giudice, G.2
  • 162
    • 0026033441 scopus 로고
    • Separation and characterization of saponins with adjuvant activity from Quillaja saponaria Molina cortex
    • Kensil C, Patel U, Lennick M, Marciani D. Separation and characterization of saponins with adjuvant activity from Quillaja saponaria Molina cortex. J Immunol 1991;146:431-437.
    • (1991) J Immunol , vol.146 , pp. 431-437
    • Kensil, C.1    Patel, U.2    Lennick, M.3    Marciani, D.4
  • 163
    • 0031661414 scopus 로고    scopus 로고
    • QS-21: A water-soluble triterpene glycoside adjuvant
    • DOI 10.1517/13543784.7.9.1475
    • Kensil C, Kammer R. QS-21: A water-soluble triterpene glycoside adjuvant. Expert Opin Investig Drugs 1998;7:1475-1482. (Pubitemid 28408808)
    • (1998) Expert Opinion on Investigational Drugs , vol.7 , Issue.9 , pp. 1475-1482
    • Read Kensil, C.1    Kammer, R.2
  • 165
    • 0037157260 scopus 로고    scopus 로고
    • Safety, tolerability and immunogenicity of new formulations of the Plasmodium falciparum malaria peptide vaccine SPf66 combined with the immunological adjuvant QS-21
    • DOI 10.1016/S0264-410X(02)00115-9, PII S0264410X02001159
    • Kashala O, Amador R, Valero MV, et al. Safety, tolerability and immunogenicity of new formulations of the Plasmodium falciparum malaria peptide vaccine SPf66 combined with the immunological adjuvant QS-21. Vaccine 2002;20:2263-2277. (Pubitemid 34497037)
    • (2002) Vaccine , vol.20 , Issue.17-18 , pp. 2263-2277
    • Kashala, O.1    Amador, R.2    Valero, M.V.3    Moreno, A.4    Barbosa, A.5    Nickel, B.6    Daubenberger, C.A.7    Guzman, F.8    Pluschke, G.9    Patarroyo, M.E.10
  • 167
    • 33947170378 scopus 로고    scopus 로고
    • Adjuvant-enhanced antibody responses to recombinant proteins correlates with protection of mice and monkeys to orthopoxvirus challenges
    • DOI 10.1016/j.vaccine.2006.12.037, PII S0264410X06013673
    • Fogg CN, Americo JL, Lustig S, et al. Adjuvant-enhanced antibody responses to recombinant proteins correlates with protection of mice and monkeys to orthopoxvirus challenges. Vaccine 2007;25:2787-2799. (Pubitemid 46412575)
    • (2007) Vaccine , vol.25 , Issue.15 , pp. 2787-2799
    • Fogg, C.N.1    Americo, J.L.2    Lustig, S.3    Huggins, J.W.4    Smith, S.K.5    Damon, I.6    Resch, W.7    Earl, P.L.8    Klinman, D.M.9    Moss, B.10
  • 171
    • 70949093173 scopus 로고    scopus 로고
    • Consolidation strategies in ovarian cancer: Observations for future clinical trials
    • Sabbatini P, Spriggs D, Aghajanian C, et al. Consolidation strategies in ovarian cancer: Observations for future clinical trials. Gynecol Oncol 2010;116:66-71.
    • (2010) Gynecol Oncol , vol.116 , pp. 66-71
    • Sabbatini, P.1    Spriggs, D.2    Aghajanian, C.3
  • 172
    • 0032943932 scopus 로고    scopus 로고
    • Evidence of a cellular immune response against sialyl-Tn in breast and ovarian cancer patients after high-dose chemotherapy, stem cell rescue, and immunization with theratope STn-KLH cancer vaccine
    • DOI 10.1097/00002371-199901000-00008
    • Sandmaier B, Oparin D, Holmberg L, et al. Evidence of a cellular immune response against sialyl-Tn in breast and ovarian cancer patients after high-dose chemotherapy, stem cell rescue, and immunization with Teratope STn-KLH cancer vaccine. J Immunother 1999;22:54-66. (Pubitemid 29042291)
    • (1999) Journal of Immunotherapy , vol.22 , Issue.1 , pp. 54-66
    • Sandmaier, B.M.1    Oparin, D.V.2    Holmberg, L.A.3    Reddish, M.A.4    MacLean, G.D.5    Longenecker, B.M.6
  • 173
    • 0346364653 scopus 로고    scopus 로고
    • Rationale for the clinical development of STn-KLH (Teratope®) and anti-MUC-1 vaccines in breast cancer
    • Miles D, Papazisis K. Rationale for the clinical development of STn-KLH (Teratope®) and anti-MUC-1 vaccines in breast cancer. Clin Breast Cancer 2003;3:S134-S138.
    • (2003) Clin Breast Cancer , vol.3
    • Miles, D.1    Papazisis, K.2
  • 174
    • 0036813199 scopus 로고    scopus 로고
    • GM-CSF-based cancer vaccines
    • Dranof G. GM-CSF-based cancer vaccines. Immunol Rev 2002;188:147-154.
    • (2002) Immunol Rev , vol.188 , pp. 147-154
    • Dranof, G.1
  • 175
    • 78751510278 scopus 로고    scopus 로고
    • Vaccination with dendritic cell/tumor fusion cells results in cellular and humoral antitumor immune responses in patients with multiple myeloma
    • Jan 13
    • Rosenblatt J, Vasir B, Uhl L, et al. Vaccination with dendritic cell/tumor fusion cells results in cellular and humoral antitumor immune responses in patients with multiple myeloma. Blood 2011 Jan 13;117:393-402.
    • (2011) Blood , vol.117 , pp. 393-402
    • Rosenblatt, J.1    Vasir, B.2    Uhl, L.3
  • 176
    • 44949195901 scopus 로고    scopus 로고
    • Results of the frst phase I/II clinical vaccination trial with direct injection of mRNA
    • Weide B, Carralot J-P, Reese A, et al. Results of the frst phase I/II clinical vaccination trial with direct injection of mRNA. J Immunother 2008;31:180-188.
    • (2008) J Immunother , vol.31 , pp. 180-188
    • Weide, B.1    Carralot, J.-P.2    Reese, A.3
  • 177
    • 41149172340 scopus 로고    scopus 로고
    • Phase I clinical trial of autologous ascites-derived exosomes combined with GM-CSF for colorectal cancer
    • DOI 10.1038/mt.2008.1, PII MT20081
    • Dai S, Wei D, Wu Z, et al. Phase I clinical trial of autologous ascites-derived exosomes combined with GM-CSF for colorectal cancer. Mol Ter 2008;16:782-790. (Pubitemid 351426181)
    • (2008) Molecular Therapy , vol.16 , Issue.4 , pp. 782-790
    • Dai, S.1    Wei, D.2    Wu, Z.3    Zhou, X.4    Wei, X.5    Huang, H.6    Li, G.7
  • 179
    • 70349242210 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor (GM-CSF)-secreting cellular immunotherapy in combination with autologous stem cell transplantation (ASCT) as postremission therapy for acute myeloid leukemia (AML)
    • Borrello IM, Levitsky HI, Stock W, et al. Granulocyte-macrophage colony-stimulating factor (GM-CSF)-secreting cellular immunotherapy in combination with autologous stem cell transplantation (ASCT) as postremission therapy for acute myeloid leukemia (AML). Blood 2009;114:1736-1745.
    • (2009) Blood , vol.114 , pp. 1736-1745
    • Borrello, I.M.1    Levitsky, H.I.2    Stock, W.3
  • 180
    • 33646776056 scopus 로고    scopus 로고
    • Phase 1/2 trial of autologous tumor mixed with an allogeneic GVAX vaccine in advanced-stage non-small-cell lung cancer
    • Nemunaitis J, Jahan T, Ross H, et al. Phase 1/2 trial of autologous tumor mixed with an allogeneic GVAX vaccine in advanced-stage non-small-cell lung cancer. Cancer Gene Ter 2006;13:555-562.
    • (2006) Cancer Gene ter , vol.13 , pp. 555-562
    • Nemunaitis, J.1    Jahan, T.2    Ross, H.3
  • 182
    • 0347600569 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor gene-transfected autologous tumor cell vaccine: Focus on non-small-cell lung cancer
    • Nemunaitis J. Granulocyte-macrophage colony-stimulating factor gene-transfected autologous tumor cell vaccine: Focus on non-small-cell lung cancer. Clin Lung Cancer 2003;5:148-157. (Pubitemid 38028804)
    • (2003) Clinical Lung Cancer , vol.5 , Issue.3 , pp. 148-157
    • Nemunaitis, J.1    Nemunaitis, J.2
  • 184
    • 74249101123 scopus 로고    scopus 로고
    • Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF
    • Dolcetti L, Peranzoni E, Ugel S, et al. Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF. Eur J Immunol 2010;40:22-35.
    • (2010) Eur J Immunol , vol.40 , pp. 22-35
    • Dolcetti, L.1    Peranzoni, E.2    Ugel, S.3
  • 185
    • 23444446779 scopus 로고    scopus 로고
    • Continuous low-dose GM-CSF as salvage therapy in refractory recurrent breast or female genital tract carcinoma
    • Kurbacher C, Kurbacher J, Cramer E, et al. Continuous low-dose GM-CSF as salvage therapy in refractory recurrent breast or female genital tract carcinoma. Oncology (Williston Park) 2005;19(4 Suppl):23-26.
    • (2005) Oncology (Williston Park) , vol.19 , Issue.4 SUPPL. , pp. 23-26
    • Kurbacher, C.1    Kurbacher, J.2    Cramer, E.3
  • 186
    • 73949126823 scopus 로고    scopus 로고
    • Phase II trial of GM-CSF in women with asymptomatic recurrent Müllerian tumors
    • Roche MR, Rudd PJ, Krasner CN, et al. Phase II trial of GM-CSF in women with asymptomatic recurrent Müllerian tumors. Gynecol Oncol 2010;116:168-172.
    • (2010) Gynecol Oncol , vol.116 , pp. 168-172
    • Roche, M.R.1    Rudd, P.J.2    Krasner, C.N.3
  • 187
    • 0025967296 scopus 로고
    • A double-blind placebo-controlled study with granulocyte-macrophage colony-stimulating factor during chemotherapy for ovarian carcinoma
    • de Vries EGE, Biesma B, Willemse PHB, et al. A double-blind placebo-controlled study with granulocyte-macrophage colony-stimulating factor during chemotherapy for ovarian carcinoma. Cancer Res 1991;51:116-122.
    • (1991) Cancer Res , vol.51 , pp. 116-122
    • De Vries, E.G.E.1    Biesma, B.2    Willemse, P.H.B.3
  • 188
    • 63749113820 scopus 로고    scopus 로고
    • A phase II study of GM-CSF and rIFN-1b plus carboplatin for the treatment of recurrent, platinum-sensitive ovarian, fallopian tube and primary peritoneal cancer
    • Schmeler KM, Vadhan-Raj S, Ramirez PT, et al. A phase II study of GM-CSF and rIFN-1b plus carboplatin for the treatment of recurrent, platinum-sensitive ovarian, fallopian tube and primary peritoneal cancer. Gynecol Oncol 2009;113:210-215.
    • (2009) Gynecol Oncol , vol.113 , pp. 210-215
    • Schmeler, K.M.1    Vadhan-Raj, S.2    Ramirez, P.T.3
  • 189
    • 65349149089 scopus 로고    scopus 로고
    • Molecular mechanism and function of CD40/CD40L engagement in the immune system
    • Elgueta R, Benson MJ, De Vries VC, et al. Molecular mechanism and function of CD40/CD40L engagement in the immune system. Immunol Rev 2009;229:152-172.
    • (2009) Immunol Rev , vol.229 , pp. 152-172
    • Elgueta, R.1    Benson, M.J.2    De Vries, V.C.3
  • 190
    • 0029051542 scopus 로고
    • A soluble form of TRAP (CD40 ligand) is rapidly released after T cell activation
    • Graf D, Müller S, Korthauer U, et al. A soluble form of TRAP (CD40 ligand) is rapidly released after T cell activation. Eur J Immunol 1995;25:1749-1754.
    • (1995) Eur J Immunol , vol.25 , pp. 1749-1754
    • Graf, D.1    Müller, S.2    Korthauer, U.3
  • 191
    • 0028905489 scopus 로고
    • Recombinant soluble trimeric CD40 ligand is biologically active
    • Mazzei GJ, Edgerton MD, Losberger C, et al. Recombinant soluble trimeric CD40 ligand is biologically active. J Biol Chem 1995;270:7025-7028.
    • (1995) J Biol Chem , vol.270 , pp. 7025-7028
    • Mazzei, G.J.1    Edgerton, M.D.2    Losberger, C.3
  • 192
    • 0029812593 scopus 로고    scopus 로고
    • Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation
    • Cella M, Scheidegger D, Palmer-Lehmann K, et al. Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation. J Exp Med 1996;184:747-752. (Pubitemid 26324129)
    • (1996) Journal of Experimental Medicine , vol.184 , Issue.2 , pp. 747-752
    • Cella, M.1    Scheidegger, D.2    Palmer-Lehmann, K.3    Lane, P.4    Lanzavecchia, A.5    Alber, G.6
  • 194
    • 0035886792 scopus 로고    scopus 로고
    • Recombinant CD40 ligand therapy has significant antitumor effects on CD40-positive ovarian tumor xenografts grown in SCID mice and demonstrates an augmented effect with cisplatin
    • Ghamande S, Hylander BL, Ofazoglu E, et al. Recombinant CD40 ligand therapy has signifcant an-titumor effects on CD40-positive ovarian tumor xenografts grown in SCID mice and demonstrates an augmented efect with cisplatin. Cancer Res 2001;61:7556-7562. (Pubitemid 32995048)
    • (2001) Cancer Research , vol.61 , Issue.20 , pp. 7556-7562
    • Ghamande, S.1    Hylander, B.L.2    Oflazoglu, E.3    Lele, S.4    Fanslow, W.5    Repasky, E.A.6
  • 196
    • 70349334508 scopus 로고    scopus 로고
    • Phase i Study of the humanized anti-CD40 monoclonal antibody dacetuzumab in refractory or recurrent non-Hodgkin's Lymphoma
    • Advani R, Forero-Torres A, Furman RR, et al. Phase I Study of the humanized anti-CD40 monoclonal antibody dacetuzumab in refractory or recurrent non-Hodgkin's Lymphoma. J Clin Oncol 2009;27:4371-4377.
    • (2009) J Clin Oncol , vol.27 , pp. 4371-4377
    • Advani, R.1    Forero-Torres, A.2    Furman, R.R.3
  • 197
    • 79955839464 scopus 로고    scopus 로고
    • A Cancer Research UK phase i study evaluating safety, tolerability, and biological effects of chimeric anti-CD40 monoclonal antibody (MAb), Chi Lob 7/4
    • suppl; abstr 2507
    • Johnson PW, Steven NM, Chowdhury F, et al. A Cancer Research UK phase I study evaluating safety, tolerability, and biological effects of chimeric anti-CD40 monoclonal antibody (MAb), Chi Lob 7/4. J Clin Oncol 2010;28 (15s (suppl; abstr 2507)).
    • (2010) J Clin Oncol , vol.28 , Issue.15 S
    • Johnson, P.W.1    Steven, N.M.2    Chowdhury, F.3
  • 198
    • 70349750194 scopus 로고    scopus 로고
    • In situ stimulation of CD40 and Toll-like receptor 3 transforms ovarian cancer-infltrating dendritic cells from immunosuppressive to immunostim-ulatory cells
    • Scarlett UK, Cubillos-Ruiz JR, Nesbeth YC, et al. In situ stimulation of CD40 and Toll-like receptor 3 transforms ovarian cancer-infltrating dendritic cells from immunosuppressive to immunostim-ulatory cells. Cancer Res 2009;69:7329-7337.
    • (2009) Cancer Res , vol.69 , pp. 7329-7337
    • Scarlett, U.K.1    Cubillos-Ruiz, J.R.2    Nesbeth, Y.C.3
  • 200
    • 0029587212 scopus 로고
    • The flt3/flk-2 ligand: Receptor distribution and action on murine haemopoietic cell survival and proliferation
    • Rasko J, Metcalf D, Rossner M, et al. The ft3/fk-2 ligand: Receptor distribution and action on murine haemopoietic cell survival and proliferation. Leukemia 1995;12:2058-2066. (Pubitemid 26023790)
    • (1995) Leukemia , vol.9 , Issue.12 , pp. 2058-2066
    • Rasko, J.E.J.1    Metcalf, D.2    Rossner, M.T.3    Begley, C.G.4    Nicola, N.A.5
  • 202
    • 0025259592 scopus 로고
    • Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (ft) closely related to the fms family
    • Shibuya M, Yamaguchi S, Yamane A, et al. Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (ft) closely related to the fms family. Oncogene 1990;5:519-524.
    • (1990) Oncogene , vol.5 , pp. 519-524
    • Shibuya, M.1    Yamaguchi, S.2    Yamane, A.3
  • 205
    • 0028203747 scopus 로고
    • Cloning of the human homologue of the murine ft3 ligand: A growth factor for early hematopoietic progenitor cells
    • Lyman S, James L, Johnson L, et al. Cloning of the human homologue of the murine ft3 ligand: A growth factor for early hematopoietic progenitor cells. Blood 1994;83:2795-2801.
    • (1994) Blood , vol.83 , pp. 2795-2801
    • Lyman, S.1    James, L.2    Johnson, L.3
  • 207
    • 0029670722 scopus 로고    scopus 로고
    • Fk2/ft3 ligand is a potent cofactor for the growth of primitive B cell progenitors
    • Hunte B, Hudak S, Campbell D, et al. fk2/ft3 ligand is a potent cofactor for the growth of primitive B cell progenitors. J Immunol 1996;156:489-496.
    • (1996) J Immunol , vol.156 , pp. 489-496
    • Hunte, B.1    Hudak, S.2    Campbell, D.3
  • 208
    • 0029957070 scopus 로고    scopus 로고
    • Flt3 ligand supports the differentiation of early B cell progenitors in the presence of interleukin-11 and interleukin-7
    • DOI 10.1002/eji.1830260715
    • Ray RJ, Paige CJ, Furlonger C, et al. Flt3 ligand supports the diferentiation of early B cell progenitors in the presence of interleukin-11 and interleukin-7. Eur J Immunol 1996;26:1504-1510. (Pubitemid 26229995)
    • (1996) European Journal of Immunology , vol.26 , Issue.7 , pp. 1504-1510
    • Ray, R.J.1    Paige, C.J.2    Furlonger, C.3    Lyman, S.D.4    Rottapel, R.5
  • 209
    • 0029097145 scopus 로고
    • Targeted disruption of the fk2/ft3 gene leads to defciencies in primitive hematopoietic progenitors
    • Mackarehtschian K, Hardin JD, Moore KA, et al. Targeted disruption of the fk2/ft3 gene leads to defciencies in primitive hematopoietic progenitors. Immunity 1995;3:147-161.
    • (1995) Immunity , vol.3 , pp. 147-161
    • MacKarehtschian, K.1    Hardin, J.D.2    Moore, K.A.3
  • 210
    • 0029992896 scopus 로고    scopus 로고
    • Ability of ft3 ligand to stimulate the in vitro growth of primitive murine hematopoietic progenitors is potently and directly inhibited by transforming growth factor-beta and tumor necrosis factor-alpha
    • Jacobsen S, Veiby O, Myklebust J, et al. Ability of ft3 ligand to stimulate the in vitro growth of primitive murine hematopoietic progenitors is potently and directly inhibited by transforming growth factor-beta and tumor necrosis factor-alpha. Blood 1996;87:5016-5026.
    • (1996) Blood , vol.87 , pp. 5016-5026
    • Jacobsen, S.1    Veiby, O.2    Myklebust, J.3
  • 213
    • 0037089223 scopus 로고    scopus 로고
    • Flt3 ligand as a vaccine adjuvant in association with HER-2/neu peptide-based vaccines in patients with HER-2/neu-overexpressing cancers
    • DOI 10.1182/blood.V99.8.2845
    • Disis ML, Rinn K, Knutson KL, et al. Flt3 ligand as a vaccine adjuvant in association with HER-2/neu peptide-based vaccines in patients with HER-2/neu-overexpressing cancers. Blood 2002;99:2845-2850. (Pubitemid 34525373)
    • (2002) Blood , vol.99 , Issue.8 , pp. 2845-2850
    • Disis, M.L.1    Rinn, K.2    Knutson, K.L.3    Davis, D.4    Caron, D.5    Dela Rosa, C.6    Schiffman, K.7
  • 214
    • 38649143862 scopus 로고    scopus 로고
    • Immunostimulatory effect of Fms-like tyrosine kinase 3 ligand on peripheral monocyte-derived dendritic cells and natural killer cells: Utilization for ovarian cancer treatment
    • Matsumura N, Mandai M, Hamanishi J, et al. Immunostimulatory efect of Fms-like tyrosine ki-nase 3 ligand on peripheral monocyte-derived dendritic cells and natural killer cells: Utilization for ovarian cancer treatment. Oncol Rep 2008;19:505-515. (Pubitemid 351176114)
    • (2008) Oncology Reports , vol.19 , Issue.2 , pp. 505-515
    • Matsumura, N.1    Mandai, M.2    Hamanishi, J.3    Yamaguchi, K.4    Fukuhara, K.5    Yagi, H.6    Higuchi, T.7    Takakura, K.8    Fujii, S.9
  • 215
    • 0034129760 scopus 로고    scopus 로고
    • Flt-3 ligand inhibits growth of human ovarian tumors engrafted in severe combined immunodeficient mice
    • DOI 10.1006/gyno.2000.5782
    • Silver DF, Hempling RE, Piver MS, Repasky EA. Flt-3 ligand inhibits growth of human ovarian tumors engrafted in severe combined immunodefcient mice. Gynecol Oncol 2000;77:377-382. (Pubitemid 30368553)
    • (2000) Gynecologic Oncology , vol.77 , Issue.3 , pp. 377-382
    • Silver, D.F.1    Hempling, R.E.2    Piver, M.S.3    Repasky, E.A.4
  • 216
    • 0030996963 scopus 로고    scopus 로고
    • Synergistic efect of FLT-3 ligand on the granulocyte colony-stimulating factor-induced mobilization of hematopoietic stem cells and progenitor cells into blood in mice
    • Sudo Y, Shimazaki C, Ashihara E, et al. Synergistic efect of FLT-3 ligand on the granulocyte colony-stimulating factor-induced mobilization of hematopoietic stem cells and progenitor cells into blood in mice. Blood 1997;89:3186-3191.
    • (1997) Blood , vol.89 , pp. 3186-3191
    • Sudo, Y.1    Shimazaki, C.2    Ashihara, E.3
  • 218
    • 18744411513 scopus 로고    scopus 로고
    • Dendritic cell-based vaccination in solid cancer
    • Stift A, Friedl J, Dubsky P, et al. Dendritic cell-based vaccination in solid cancer. J Clin Oncol 2003;21:135-142.
    • (2003) J Clin Oncol , vol.21 , pp. 135-142
    • Stift, A.1    Friedl, J.2    Dubsky, P.3
  • 220
    • 0033819308 scopus 로고    scopus 로고
    • Immunization of cancer patients with autologous cancer-derived heat shock protein gp96 preparations: A pilot study
    • Janetzki S, Palla D, Rosenhauer V, et al. Immunization of cancer patients with autologous cancer-derived heat shock protein gp96 preparations: a pilot study. Int J Cancer 2000;88:232-238.
    • (2000) Int J Cancer , vol.88 , pp. 232-238
    • Janetzki, S.1    Palla, D.2    Rosenhauer, V.3
  • 221
    • 0035925566 scopus 로고    scopus 로고
    • Autologous, hapten-modified vaccine as a treatment for human cancers
    • DOI 10.1016/S0264-410X(00)00490-4, PII S0264410X00004904
    • Berd D. Autologous, hapten-modifed vaccine as a treatment for human cancers. Vaccine 2001;19:2565-2570. (Pubitemid 32234273)
    • (2001) Vaccine , vol.19 , Issue.17-19 , pp. 2565-2570
    • Berd, D.1
  • 223
    • 79956018406 scopus 로고    scopus 로고
    • MHC class I-presented tumor antigens identifed in ovarian cancer by immunoproteomic analysis are targets for T cell responses against breast and ovarian cancer
    • Feb 7. DOI:10.1158/1078-0432. CCR-10-2614
    • Morse MA, Alvarez Secord A, Blackwell KL, et al. MHC class I-presented tumor antigens identifed in ovarian cancer by immunoproteomic analysis are targets for T cell responses against breast and ovarian cancer. Clin Cancer Res 2011 Feb 7. DOI:10.1158/1078-0432. CCR-10-2614.
    • (2011) Clin Cancer Res
    • Ma, M.1    Alvarez Secord, A.2    Blackwell, K.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.