Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 8, 2003, Pages 4712-4717

  Hodi, F Stephen ^a   Mihm, Martin C ^b   Soiffer, Robert J ^a   Haluska, Frank G ^b   Butler, Marcus ^a   Seiden, Michael V ^b   Davis, Thomas ^c   Henry Spires, Rochele ^a   MacRae, Suzanne ^a   Willman, Ann ^a   Padera, Robert ^a   Jaklitsch, Michael T ^a   Shankar, Sridhar ^d   Chen, Teresa C ^d   Korman, Alan ^c   Allison, James P ^e   Dranoff, Glenn ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c MEDAREX INC   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CA 125 ANTIGEN; CANCER VACCINE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4 ANTIBODY; GANGLIOSIDE GM2; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR; MDX CTLA 4 ANTIBODY; QS 21; UNCLASSIFIED DRUG;

ADULT; ANOREXIA; ANTINEOPLASTIC ACTIVITY; ARTHRALGIA; ARTICLE; AUTOIMMUNITY; BLOOD LEVEL; CANCER IMMUNIZATION; CANCER RADIOTHERAPY; CELL INFILTRATION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COUGHING; DRUG ACTIVITY; DRUG EFFECT; FATIGUE; FEMALE; GRANULOCYTE; HUMAN; HYPERSENSITIVITY; HYPOTENSION; IRRADIATION; LIVER FUNCTION; LYMPHOCYTIC INFILTRATION; MALE; MELANOCYTE; MELANOMA; METASTASIS; MYALGIA; NAUSEA; NOSE CONGESTION; OVARY CARCINOMA; PRIORITY JOURNAL; SECRETORY CELL; SIDE EFFECT; T LYMPHOCYTE; TREATMENT OUTCOME; TUMOR CELL; TUMOR GROWTH; TUMOR IMMUNITY; TUMOR NECROSIS;

ADULT; AGED; ANIMALS; ANTIBODIES, BLOCKING; ANTIBODIES, MONOCLONAL; ANTIGEN PRESENTATION; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION; CANCER VACCINES; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; HUMANS; IMMUNOCONJUGATES; MALE; MELANOMA; MICE; MIDDLE AGED; NECROSIS; OVARIAN NEOPLASMS;

MURINAE;

EID: 0344341626     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0830997100     Document Type: Article

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