Monophosphoryl lipid A plus IFNγ maturation of dendritic cells induces antigen-specific CD8+ cytotoxic T cells with high cytolytic potential

Cancer Immunology, Immunotherapy

Volumn 59, Issue 8, 2010, Pages 1185-1195

  Ten Brinke, Anja ^a   Van Schijndel, Gijs ^a   Visser, Remco ^a   De Gruijl, Tanja D ^c   Zwaginga, Jaap Jan ^a,b   Van Ham, S Marieke ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Cytotoxic T lymphocyte; Dendritic cells; IL 12; Immunotherapy; MART 1; Monophosphoryl lipid A

Indexed keywords

B7 ANTIGEN; CD4 ANTIGEN; CD40 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; DENDRITIC CELL VACCINE; GAMMA INTERFERON; HLA ANTIGEN; HLA DR ANTIGEN; INTERLEUKIN 12; INTERLEUKIN 2; INTERLEUKIN 7; MELAN A; PHOSPHORYL LIPID A; TUMOR ANTIGEN;

ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ANTIGEN SPECIFICITY; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL KILLING; CELL MATURATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MELANOMA; PHENOTYPE; PRIORITY JOURNAL; TARGET CELL; TH1 CELL; TUMOR CELL DESTRUCTION;

ADJUVANTS, IMMUNOLOGIC; ANTIGENS, CD4; ANTIGENS, CD8; ANTIGENS, NEOPLASM; CELL DIFFERENTIATION; CELLS, CULTURED; CYTOTOXICITY, IMMUNOLOGIC; DENDRITIC CELLS; HLA ANTIGENS; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-12; LIPID A; LYMPHOCYTE ACTIVATION; MELANOMA; T-LYMPHOCYTES, CYTOTOXIC; TH1 CELLS; TOLL-LIKE RECEPTORS;

EID: 77953231072     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-010-0843-z     Document Type: Article

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