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Volumn 20, Issue 27-28, 2002, Pages 3389-3398

Synergistic adjuvant activity of immunostimulatory DNA and oil/water emulsions for immunization with HIV p55 gag antigen

Author keywords

CpG; HIV; MF59 adjuvant

Indexed keywords

DNA VACCINE; HEPATITIS B SURFACE ANTIGEN; HUMAN IMMUNODEFICIENCY VIRUS ANTIGEN; IMMUNOGLOBULIN G2A; N ACETYLMURAMYLALANYL DEXTRO ISOGLUTAMINYLALANYL DIPALMITOYLPHOSPHATIDYLETHANOLAMINE; OLIGONUCLEOTIDE; POLYGLACTIN; PROTEIN P55; UREA; VIRUS ANTIBODY; VIRUS PROTEIN; WATER OIL CREAM;

EID: 0037056053     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(02)00272-4     Document Type: Article
Times cited : (38)

References (44)
  • 1
    • 0021256125 scopus 로고
    • Antitumor activity of deoxyribonucleic acid fraction from Mycobacterium bovis BCG. Part I. Isolation, physicochemical characterization, and antitumor activity
    • Tokunaga T., Yamamoto H., Shimada S.et al. Antitumor activity of deoxyribonucleic acid fraction from Mycobacterium bovis BCG. Part I. Isolation, physicochemical characterization, and antitumor activity. J. Natl. Cancer Inst. 72(4):1984;955-962.
    • (1984) J. Natl. Cancer Inst. , vol.72 , Issue.4 , pp. 955-962
    • Tokunaga, T.1    Yamamoto, H.2    Shimada, S.3
  • 2
    • 0026006734 scopus 로고
    • Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA
    • Messina J.P., Gilkeson G.S., Pisetsky D.S. Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA. J. Immunol. 147(6):1991;1759-1764.
    • (1991) J. Immunol. , vol.147 , Issue.6 , pp. 1759-1764
    • Messina, J.P.1    Gilkeson, G.S.2    Pisetsky, D.S.3
  • 3
    • 0028931102 scopus 로고
    • CpG motifs in bacterial DNA trigger direct B-cell activation
    • Krieg A.M., Yi A.K., Matson S.et al. CpG motifs in bacterial DNA trigger direct B-cell activation. Nature. 374(6522):1995;546-549.
    • (1995) Nature , vol.374 , Issue.6522 , pp. 546-549
    • Krieg, A.M.1    Yi, A.K.2    Matson, S.3
  • 4
    • 0023472826 scopus 로고
    • CpG islands as gene markers in the vertebrate nucleus
    • Bird A.P. CpG islands as gene markers in the vertebrate nucleus. Trends Genet. 3:1987;342-347.
    • (1987) Trends Genet. , vol.3 , pp. 342-347
    • Bird, A.P.1
  • 5
    • 0031739939 scopus 로고    scopus 로고
    • Introduction: The role of innate immunity in the adaptive immune response
    • Janeway C.A., Medzhitov R. Introduction: the role of innate immunity in the adaptive immune response. Semin. Immunol. 10(5):1998;349-350.
    • (1998) Semin. Immunol. , vol.10 , Issue.5 , pp. 349-350
    • Janeway, C.A.1    Medzhitov, R.2
  • 6
    • 0028201732 scopus 로고
    • Tolerance, danger, and the extended family
    • Matzinger P. Tolerance, danger, and the extended family. Ann. Rev. Immunol. 12:1994;991-1045.
    • (1994) Ann. Rev. Immunol. , vol.12 , pp. 991-1045
    • Matzinger, P.1
  • 7
    • 0031867535 scopus 로고    scopus 로고
    • Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells
    • Sparwasser T., Koch E.S., Vabulas R.M.et al. Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells. Eur. J. Immunol. 28(6):1998;2045-2054.
    • (1998) Eur. J. Immunol. , vol.28 , Issue.6 , pp. 2045-2054
    • Sparwasser, T.1    Koch, E.S.2    Vabulas, R.M.3
  • 8
    • 0032732168 scopus 로고    scopus 로고
    • Antagonism of immunostimulatory CpG oligonucleotides by 4-aminoquinolines and other weak bases: Mechanistic studies
    • Manzel L, Strekowski L, Ismail F, Smith JE, Macfarlane O. Antagonism of immunostimulatory CpG oligonucleotides by 4-aminoquinolines and other weak bases: Mechanistic studies, J Pharmacol Exp Ther, 1999.
    • (1999) J Pharmacol Exp Ther
    • Manzel, L.1    Strekowski, L.2    Ismail, F.3    Smith, J.E.4    Macfarlane, O.5
  • 9
    • 0034619794 scopus 로고    scopus 로고
    • A toll-like receptor recognizes bacterial DNA
    • Hemmi H., Takeuchi O., Kawaii T.et al. A toll-like receptor recognizes bacterial DNA. Nature. 408:2000;740-745.
    • (2000) Nature , vol.408 , pp. 740-745
    • Hemmi, H.1    Takeuchi, O.2    Kawaii, T.3
  • 10
    • 0033637315 scopus 로고    scopus 로고
    • DNA PKcs is required for activation of innate immunity by immunostimulatory DNA
    • Chu W., Gong X., Li Z.et al. DNA PKcs is required for activation of innate immunity by immunostimulatory DNA. Cell. 103:2000;909-918.
    • (2000) Cell , vol.103 , pp. 909-918
    • Chu, W.1    Gong, X.2    Li, Z.3
  • 11
    • 0032476602 scopus 로고    scopus 로고
    • CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation
    • Hacker H., Mischak H., Miethke T.et al. CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation. EMBO J. 17(21):1998;6230-6240.
    • (1998) EMBO J. , vol.17 , Issue.21 , pp. 6230-6240
    • Hacker, H.1    Mischak, H.2    Miethke, T.3
  • 12
    • 0031964257 scopus 로고    scopus 로고
    • CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen [published erratum appears in J Immunol 1 March 1999;162(5):3103]
    • Davis H.L., Weeratna R., Waldschmidt T.J.et al. CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen [published erratum appears in J Immunol 1 March 1999;162(5):3103]. J. Immunol. 160(2):1998;870-876.
    • (1998) J. Immunol. , vol.160 , Issue.2 , pp. 870-876
    • Davis, H.L.1    Weeratna, R.2    Waldschmidt, T.J.3
  • 13
    • 0032489829 scopus 로고    scopus 로고
    • DNA as an adjuvant: Capacity of insect DNA and synthetic oligodeoxynucleotides to augment T cell responses to specific antigen
    • Sun S., Kishimoto H., Sprent J. DNA as an adjuvant: capacity of insect DNA and synthetic oligodeoxynucleotides to augment T cell responses to specific antigen. J. Exp. Med. 187(7):1998;1145-1150.
    • (1998) J. Exp. Med. , vol.187 , Issue.7 , pp. 1145-1150
    • Sun, S.1    Kishimoto, H.2    Sprent, J.3
  • 14
    • 0004582004 scopus 로고    scopus 로고
    • CpG DNA can induce strong Th1 humoral and cell-mediated immune responses against hepatitis B surface antigen in young mice
    • Brazolot Millan C.L., Weeratna R., Krieg A.M., Siegrist C.A., Davis H.L. CpG DNA can induce strong Th1 humoral and cell-mediated immune responses against hepatitis B surface antigen in young mice. Proc. Natl. Acad. Sci. U.S.A. 95(26):1998;15553-15558.
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , Issue.26 , pp. 15553-15558
    • Brazolot Millan, C.L.1    Weeratna, R.2    Krieg, A.M.3    Siegrist, C.A.4    Davis, H.L.5
  • 15
    • 0032534602 scopus 로고    scopus 로고
    • Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice
    • Broide D., Schwarze J., Tighe H.et al. Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice. J. Immunol. 161(12):1998;7054-7062.
    • (1998) J. Immunol. , vol.161 , Issue.12 , pp. 7054-7062
    • Broide, D.1    Schwarze, J.2    Tighe, H.3
  • 16
    • 0033529891 scopus 로고    scopus 로고
    • CpG DNA: A potent signal for growth, activation, and maturation of human dendritic cells
    • Hartmann G., Weiner G.J., Krieg A.M. CpG DNA: a potent signal for growth, activation, and maturation of human dendritic cells. Proc. Natl. Acad. Sci. U.S.A. 96(16):1999;9305-9310.
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , Issue.16 , pp. 9305-9310
    • Hartmann, G.1    Weiner, G.J.2    Krieg, A.M.3
  • 17
    • 0032810718 scopus 로고    scopus 로고
    • DNA activates human immune cells through a CpG sequence-dependent manner
    • Baner M., Heeg K., Wagner H., Lipford G.B. DNA activates human immune cells through a CpG sequence-dependent manner. Immunology. 97(4):1999;699-705.
    • (1999) Immunology , vol.97 , Issue.4 , pp. 699-705
    • Baner, M.1    Heeg, K.2    Wagner, H.3    Lipford, G.B.4
  • 18
    • 0034142182 scopus 로고    scopus 로고
    • Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo
    • Hartmann G., Weeratna R.D., Ballas Z.K.et al. Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo. J. Immunol. 164(3):2000;1617-1624.
    • (2000) J. Immunol. , vol.164 , Issue.3 , pp. 1617-1624
    • Hartmann, G.1    Weeratna, R.D.2    Ballas, Z.K.3
  • 19
    • 17944402906 scopus 로고    scopus 로고
    • CpG DNA overcomes hyporesponsiveness to hepatitis B vaccine in orangutans
    • Davis H.L., Suparto I.I., Weeratna R.R.et al. CpG DNA overcomes hyporesponsiveness to hepatitis B vaccine in orangutans. Vaccine. 18(18):2000;1920-1924.
    • (2000) Vaccine , vol.18 , Issue.18 , pp. 1920-1924
    • Davis, H.L.1    Suparto, I.I.2    Weeratna, R.R.3
  • 21
  • 22
    • 0032565591 scopus 로고    scopus 로고
    • Dendritic cells intemalize vaccine adjuvant after intramuscular injection
    • Dupuis M., Murphy T.J., Higgins D.et al. Dendritic cells intemalize vaccine adjuvant after intramuscular injection. Cell Immunol. 186(1):1998;18-27.
    • (1998) Cell Immunol. , vol.186 , Issue.1 , pp. 18-27
    • Dupuis, M.1    Murphy, T.J.2    Higgins, D.3
  • 23
    • 0033997105 scopus 로고    scopus 로고
    • Microparticles in MF59, a potent adjuvant combination for a recombinant protein vaccine against HTV-1
    • O'Hagan D.T., Ugozzoli M., Barackman J.et al. Microparticles in MF59, a potent adjuvant combination for a recombinant protein vaccine against HTV-1. Vaccine. 18(17):2000;1793-1801.
    • (2000) Vaccine , vol.18 , Issue.17 , pp. 1793-1801
    • O'Hagan, D.T.1    Ugozzoli, M.2    Barackman, J.3
  • 24
    • 0034601242 scopus 로고    scopus 로고
    • Novel anionic microparticles are a potent adjuvant for the induction of cytotoxic T lymphocytes against recombinant p55 gag from HTV-1
    • Kazzaz J., Neidleman J., Singh M., Ott G., O'Hagan D.T. Novel anionic microparticles are a potent adjuvant for the induction of cytotoxic T lymphocytes against recombinant p55 gag from HTV-1. J. Control Release. 67(2-3):2000;347-356.
    • (2000) J. Control Release , vol.67 , Issue.2-3 , pp. 347-356
    • Kazzaz, J.1    Neidleman, J.2    Singh, M.3    Ott, G.4    O'Hagan, D.T.5
  • 25
    • 0033997899 scopus 로고    scopus 로고
    • CpG DNA induces stronger immune responses with less toxicity than other adjuvants
    • Weeratna R.D., McCluskie M.J., Xu Y., Davis H.L. CpG DNA induces stronger immune responses with less toxicity than other adjuvants. Vaccine. 18(17):2000;1755-1762.
    • (2000) Vaccine , vol.18 , Issue.17 , pp. 1755-1762
    • Weeratna, R.D.1    McCluskie, M.J.2    Xu, Y.3    Davis, H.L.4
  • 27
    • 0031020339 scopus 로고    scopus 로고
    • Adjuvant modulation of immune responses to tuberculosis vaccines
    • Lindblad E., Elhay M., Silva R., Appelberg R., Andersen P. Adjuvant modulation of immune responses to tuberculosis vaccines. Infect. Immun. 65(2):1997;623-629.
    • (1997) Infect. Immun. , vol.65 , Issue.2 , pp. 623-629
    • Lindblad, E.1    Elhay, M.2    Silva, R.3    Appelberg, R.4    Andersen, P.5
  • 29
    • 0027984259 scopus 로고
    • Systemic cytokine profiles in BALB/c mice immunized with trivalent influenza vaccine containing MF59 oil emulsion and other advanced adjuvants
    • Valensi J.P., Carison J.R., Van Nest G.A. Systemic cytokine profiles in BALB/c mice immunized with trivalent influenza vaccine containing MF59 oil emulsion and other advanced adjuvants. J. Immunol. 153(9):1994;4029-4039.
    • (1994) J. Immunol. , vol.153 , Issue.9 , pp. 4029-4039
    • Valensi, J.P.1    Carison, J.R.2    Van Nest, G.A.3
  • 30
    • 0033179147 scopus 로고    scopus 로고
    • Critical role of costimulation in the activation of naive antigen-specific TCR transgenic CD8+ T cells in vitro
    • Chai J., Vendetti S., bartok I.et al. Critical role of costimulation in the activation of naive antigen-specific TCR transgenic CD8+ T cells in vitro. J. Immunol. 163(3):1999;1298-1305.
    • (1999) J. Immunol , vol.163 , Issue.3 , pp. 1298-1305
    • Chai, J.1    Vendetti, S.2    Bartok, I.3
  • 31
    • 0035122538 scopus 로고    scopus 로고
    • Interleukin-4 acts at the locus of the antigen-presenting dendritic cell to counter regulate cytotoxic CD8+ T cell responses
    • King C.A., Mueller Hoenger R., Cleary M.et al. Interleukin-4 acts at the locus of the antigen-presenting dendritic cell to counter regulate cytotoxic CD8+ T cell responses. Nature Med. 7(7):2001;206-214.
    • (2001) Nature Med , vol.7 , Issue.7 , pp. 206-214
    • King, C.A.1    Mueller Hoenger, R.2    Cleary, M.3
  • 32
    • 0019985965 scopus 로고
    • Synthesis and assembly of hepatitis B virus surface antigen particles in yeast
    • Valenzuela P., Medina A., Rutter W.J., Ammerer G., Hall B.D. Synthesis and assembly of hepatitis B virus surface antigen particles in yeast. Nature. 298(5872):1982;347-350.
    • (1982) Nature , vol.298 , Issue.5872 , pp. 347-350
    • Valenzuela, P.1    Medina, A.2    Rutter, W.J.3    Ammerer, G.4    Hall, B.D.5
  • 33
    • 0031800888 scopus 로고    scopus 로고
    • CpG DNA, a novel immune enhancer for systemic and mucosal immunization with influenza virus
    • Moldoveanu Z., Love-Homan L., Huang W.Q., Krieg A.M. CpG DNA, a novel immune enhancer for systemic and mucosal immunization with influenza virus. Vaccine. 16(11-12):1998;1216-1224.
    • (1998) Vaccine , vol.16 , Issue.11-12 , pp. 1216-1224
    • Moldoveanu, Z.1    Love-Homan, L.2    Huang, W.Q.3    Krieg, A.M.4
  • 34
    • 0034680145 scopus 로고    scopus 로고
    • Toll-like receptors in the induction of the innate immune response
    • Aderem A., Ulevitch R. Toll-like receptors in the induction of the innate immune response. Nature. 406:2000;782-787.
    • (2000) Nature , vol.406 , pp. 782-787
    • Aderem, A.1    Ulevitch, R.2
  • 35
    • 0034623661 scopus 로고    scopus 로고
    • Immune effects and mechanisms of action of CpG motifs
    • Krieg A.M. Immune effects and mechanisms of action of CpG motifs. Vaccine. 19:2001;68-622.
    • (2001) Vaccine , vol.19 , pp. 68-622
    • Krieg, A.M.1
  • 36
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau J., Steinman R.M. Dendritic cells and the control of immunity. Nature. 392(6673):1998;245-252.
    • (1998) Nature , vol.392 , Issue.6673 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 37
    • 0033401590 scopus 로고    scopus 로고
    • CpG DNA switches on Thi immunity and modulates antigen-presenting cell function
    • Chu R.S., Askew D., Harding C.V. CpG DNA switches on Thi immunity and modulates antigen-presenting cell function. Current Topics Microbiol Immunol. 247:2000;199-210.
    • (2000) Current Topics Microbiol Immunol , vol.247 , pp. 199-210
    • Chu, R.S.1    Askew, D.2    Harding, C.V.3
  • 38
    • 0034698739 scopus 로고    scopus 로고
    • Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6
    • Hacker H., Vabulas R., Takeuchi O., Hoshino K., Akira S., Wagner H. Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6. J Exp Med. 192(4):2000;595-600.
    • (2000) J Exp Med , vol.192 , Issue.4 , pp. 595-600
    • Hacker, H.1    Vabulas, R.2    Takeuchi, O.3    Hoshino, K.4    Akira, S.5    Wagner, H.6
  • 39
    • 0030240062 scopus 로고    scopus 로고
    • Macrophages ingest and are activated by bacterial DNA
    • Stacey K.J., Sweet M.J., Hume D.A. Macrophages ingest and are activated by bacterial DNA. J. Imnunol. 157(5):1996;2116-2122.
    • (1996) J. Imnunol. , vol.157 , Issue.5 , pp. 2116-2122
    • Stacey, K.J.1    Sweet, M.J.2    Hume, D.A.3
  • 40
    • 0030816325 scopus 로고    scopus 로고
    • Macrophages sense pathogens via DNA motifs: Induction of tumor necrosis factor-alpha-mediated shock
    • Sparwasser T., Miethke T., Lipford G.et al. Macrophages sense pathogens via DNA motifs: induction of tumor necrosis factor-alpha-mediated shock. Eur. J. Immunol. 27(7):1997;1671-1679.
    • (1997) Eur. J. Immunol. , vol.27 , Issue.7 , pp. 1671-1679
    • Sparwasser, T.1    Miethke, T.2    Lipford, G.3
  • 41
    • 0032525023 scopus 로고    scopus 로고
    • CpG motifs in bacterial DNA activate leukocytes through the pH-dependent generation of reactive oxygen species
    • Yi A.K., Tuetken R., Redford T., Waldschmidt M., Kirsch J., Krieg A.M. CpG motifs in bacterial DNA activate leukocytes through the pH-dependent generation of reactive oxygen species. J. Immunol. 160(10):1998;4755-4761.
    • (1998) J. Immunol. , vol.160 , Issue.10 , pp. 4755-4761
    • Yi, A.K.1    Tuetken, R.2    Redford, T.3    Waldschmidt, M.4    Kirsch, J.5    Krieg, A.M.6
  • 42
    • 0034283956 scopus 로고    scopus 로고
    • Distribution of DNA vaccines deterrnines their immunogenicity after intramuscular injection in mice
    • Dupuis M., Denis-Mize K., Woo C.et al. Distribution of DNA vaccines deterrnines their immunogenicity after intramuscular injection in mice. J. Immunol. 165(5):2000;2850-2858.
    • (2000) J. Immunol. , vol.165 , Issue.5 , pp. 2850-2858
    • Dupuis, M.1    Denis-Mize, K.2    Woo, C.3
  • 43
    • 0034681126 scopus 로고    scopus 로고
    • Cationic microparticles: A potent delivery system for DNA vaccines
    • Singh M., Briones M., Ott G., O'Hagan D. Cationic microparticles: a potent delivery system for DNA vaccines. Proc. Natl. Acad. Sci. USA. 97(2):2000;811-816.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , Issue.2 , pp. 811-816
    • Singh, M.1    Briones, M.2    Ott, G.3    O'Hagan, D.4
  • 44
    • 17744380618 scopus 로고    scopus 로고
    • Plasmid DNA adsorbed onto PLG-CTAB microparticles mediates target gene expression and antigen presentation by dendritic cells
    • Denis-Mize K.S., Dupuis M., MacKichan M.L.et al. Plasmid DNA adsorbed onto PLG-CTAB microparticles mediates target gene expression and antigen presentation by dendritic cells. Gene Ther. 7:2000;2105-2112.
    • (2000) Gene Ther , vol.7 , pp. 2105-2112
    • Denis-Mize, K.S.1    Dupuis, M.2    MacKichan, M.L.3


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