Oxidation of defined antigens allows protein unfolding and increases both proteolytic processing and exposes peptide epitopes which are recognized by specific T cells

Immunology

Volumn 95, Issue 3, 1998, Pages 314-321

  Carrasco Marin E ^a   Paz Miguel, J E ^a   Lopez Mato P ^a   Alvarez Dominguez C ^a   Leyva Cobian F ^a  

^a HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA LACTALBUMIN; AMINOGUANIDINE; ANTIGEN; BIS[3 [3 METHYL 1 [4 (2,3,4 TRIMETHOXYBENZYL) 1 PIPERAZINYLCARBONYL]BUTYLCARBAMOYL]OXIRANE 2 CARBOXYLIC ACID ETHYL ESTER] HYDROGEN SULFATE; CITRININ; DIMETHYLUREA; EPITOPE; HYDROGEN PEROXIDE; LYSOZYME; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MANNITOL; OVALBUMIN; REACTIVE OXYGEN METABOLITE; ROTENONE; SCAVENGER;

ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; DISULFIDE BOND; FEMALE; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MOUSE; NONHUMAN; OXIDATION; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN DENATURATION; REDUCTION; T LYMPHOCYTE;

ANIMALS; ANTIGEN PRESENTATION; ANTIGENS; EPITOPES; FEMALE; FREE RADICAL SCAVENGERS; HISTOCOMPATIBILITY ANTIGENS CLASS II; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MITOCHONDRIA; NITROGEN; OXIDATION-REDUCTION; PROTEINS; REACTIVE OXYGEN SPECIES; T-LYMPHOCYTES;

EID: 0031762701     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1998.00618.x     Document Type: Article

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