flk2/flt3 Ligand is a potent cofactor for the growth of primitive B cell progenitors

Journal of Immunology

Volumn 156, Issue 2, 1996, Pages 489-496

  Hunte, Brisdell E ^a   Hudak, Susan ^a   Campbell, Dave ^a   Xu, Yuming ^a   Rennick, Donna ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD24 ANTIGEN; CD45 ANTIGEN; INTERLEUKIN 6; LEUKOSIALIN;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; B LYMPHOBLAST; B LYMPHOCYTE DIFFERENTIATION; GROWTH REGULATION; GROWTH STIMULATION; HUMAN; LYMPHOCYTE PROLIFERATION; LYMPHOPOIESIS; MOUSE; PRIORITY JOURNAL;

ANIMALS; ANTIBODY FORMATION; ANTIGENS, CD; ANTIGENS, CD24; ANTIGENS, CD43; ANTIGENS, CD45; B-LYMPHOCYTE SUBSETS; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL DIVISION; DRUG SYNERGISM; FEMALE; FMS-LIKE TYROSINE KINASE 3; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; IMMUNOPHENOTYPING; INTERLEUKIN-7; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; RECOMBINANT PROTEINS; SIALOGLYCOPROTEINS; SIGNAL TRANSDUCTION; STEM CELL FACTOR;

EID: 0029670722     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Kincade, P. W., G. Lee, C. E. Pietrangeli, S I. Hayashi, and J. M. Gimble. 1989. Cells and molecules that regulate B lymphopoiesis in bone marrow. Annu. Rev. Immunol. 7:111.
2. Dorshkind, K., and K. S. Landreth. 1992. Regulation of B cell differentiation by bone marrow stromal cells. Int. J. Cell Cloning 10:12.
3. Jacobsen, K., and D G Osmond. 1990. Microenvironmental organization and stromal cell associations of B lymphocyte precursor cells in mouse bone marrow. Eur. J Immunol 20:2393
4. Osmond, D. G 1990 B cell development in the bone marrow. Semin Immunol. 2:173.
5. Whitlock, C., K. Denis, D. Robertson, and O. Witte. 1985. In vitro analysis of murine B-cell development. Annu. Rev. Immunol. 3:213.
6. Collins, L. S., and K. Dorshkind 1987 A stromal cell line from myeloid long-term bone marrow cultures can support myelopoiesis and B lymphopoiesis. J. Immunol 138.1082.
7. Kincade, P. W. 1991. Molecular interactions between stromal cells and B lymphocyte precursors. Semin Immunol. 3:379
8. Nishikawa, S.I , M Ogawa, S. Nishikawa, T Kumisada, and H. Kodama. 1988 B lymphopoiesis on stromal cell clones: stromal cell clones acting on different stages of B cell differentiation. Eur. J. Immunol. 18:1767.
9. Rennick, D , J Jackson, C. Moulds, F. Lee, and G Yang. 1989. IL-3 and stromal cell-derived factor synergistically stimulate the growth of pre-B cell lines cloned from long-term lymphoid bone marrow cultures. J. Immunol. 142:161
10. Hayashi, S. I., T Kunisada, M. Ogawa, T. Sudo, H. Kodama, T. Suda, S. Nishikawa, and S. I. Nishikawa. 1990. Stepwise progression of B lineage differentiation supported by interleukin 7 and other stromal cell molecules J. Exp. Med. 171:1683
11. Billips, L. G., D Petitte, K. Dorshkind, R. Narayanan, C.-P. Chiu, and K. S. Landreth. 1992. Differential roles of stromal cells, interleukin-7, and kit-ligand in the regulation of B lymphopoiesis. Blood 79:1185.
12. Palacios, R., and J. Samaridis. 1992. Fetal liver pro-B and pre-B lymphocyte clones: expression of lymphoid-specific genes, surface markers, growth requirements, colonization of the bone marrow, and generation of B lymphocytes in vivo and in vitro. Mol. Cell Biol. 12.518.
13. Hardy, R R., C. E. Carmack, S. A. Shinton, J. D Kemp, and K. Hayakawa 1991. Resolution and characterization of pro-B and pre-B cell stages in normal mouse bone marrow. J. Exp. Med. 173:1213
14. Melchers, F., D Haasner, M. Streb, and A Rolink. 1992. B- lymphocyte lineage-committed, IL-7, and stroma cell-reactive progenitors and precursors, and their differentiation to B cells. In Mechanisms of Lymphocyte Activation and Immune Regulation IV Cellular Communications S. Gupta, and T. A. Waldmann. eds. Plenum Press, New York, p. 111
15. Faust, E. A., D C. Saffran, D. Toksoz, D. A. Williams, and O. N. Witte. 1993. Distinctive growth requirements and gene expression patterns distinguish progenitor B cells from pre-B cells. J Exp. Med. 177:915.
16. Funk, P. E , A Varas, and P. L Witte. 1993. Activity of stem cell factor and IL-7 in combination on normal bone marrow B lineage cells. J Immunol. 150:748.
17. McNeice, I. A., K. E. Langley, and K. M Zsebo. 1991. The role of recombinant stem cell factor in early B cell development-synergistic interaction with IL-7. J Immunol 146.3785
18. Rolink, A., M Streb, S. Nishikawa, and F. Melchers. 1991. The c-kit-encoded tyrosine kinase regulates the proliferation of early pre-B cells. Eur. J. Immunol. 21:2609.
19. Landreth, K. S., R Narayanan, and K Dorshkind. 1992. Insulin-like growth factor-1 regulates pro-B cell differentiation Blood 80:1207.
20. Nagasawa, T., H. Kikutani, and T. Kishimoto. 1994. Molecular cloning and structure of a pre-B-cell growth-stimulating factor. Proc. Natl. Acad. Sci. USA 91: 2305.
21. + B cells and produces a novel growth factor affecting B and T lineage cells. Exp. Hematol. 22:321.
22. Hannum, C., J Culpepper, D Campbell, T. McClanahan, S. Zurawski, J. F. Bazan, R Kastelein, S. Hudak, J. Wagner, J Mattson, J. Luh, G. Duda, N. Martina, D. Peterson, S, Menon, A Shanafelt, M. Muerich, G. Kelner, R. Namikawa, D. Rennick, M.-G. Roncarolo, A. Zlotnik, O. Rosnet, P. Dubreuil. D Birnbaum, and F. Lee 1994. Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs Nature 368:643.
23. Lyman, S D., L. James, T. Vanden Bos, P de Vries, K. Brasel, B. Gliniak, L. T. Hollingsworth, K. S. Picha, H. J McKenna, R. R. Splett, F. A. Fletcher, E. Maraskovsky, T. Farrah, D. Foxworthe, D. E. Williams, and M. P. Beckmann. 1993. Molecular cloning of a ligand for the flt3/flk2 tyrosine kinase receptor: a proliferative factor for primitve hematopoeitic cells. Cell 75.1157.
24. Matthews, W., C. T. Jordan, G. W. Wiegand, D. Pardoll, and I. R. Lemischka. 1991. A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations. Cell 65:1143.
25. Rosnet, O , S. Marchetto, O. deLapeyriere, and D. Birnbaum. 1991. Murine Flt3, a gene encoding a novel tyrosine kinase receptor of the PDGFR1/CSFR1 family. Oncogene 6:1641
26. Rosnet, O , C. Schiff, M.-J. Pebusque, S Marchetto, C Tonnelle, Y. Totron, F. Birg, and B D. 1993. Human FLT3/FLK2 gene: cDNA cloning and expression in hematopoietic cells. Blood 82.1110.
27. Wasserman, R., Y.-S. Li, and R. R. Hardy 1995. Differential expression on the Blk and Ret tyrosine kinases during B lineage development is dependent on Ig rearrangement J Immunol. 155.644.
28. Muench, M. O., M.-G. Roncarolo, S. Menon, Y. Xu, R. Kastelein, S. Zurawski, C. H. Hannum. J Culpepper, and R, Namikawa. 1995 flk-2/flt-3 ligand regulates the growth of early myeloid progenitors isolated from human fetal liver. Blood 85:963
29. Hudak, S., B. E Hunte, J. Culpepper, S Menon, C. Hannum, L. Thompson-Snipes, and D Rennick 1995. flt3/flk2 ligand promotes the growth of murine stem cells and the expansion of colony-forming cells and spleen colony-forming units. Blood 85:2747
30. Hirayama, F. S. D Lyman, S. C Clark, and M Ogawa. 1995. The flt3 ligand supports proliferation of lymphohematopoietic progenitors and early B-lymphoid progenitors. Blood 85.1762.
31. Rennick, D., G. Yang, L. Gemmell, and F Lee. 1987. Control of hemopoiesis by a bone marrow stromal cell clone: lipopolysaccharide- and Interleukin-1 inducible production of colony-stimulation factors. Blood 69:682.
32. Chiu, C. P., C. Moulds, R. L. Coffman, D. Rennick, and F. Lee. 1988. Multiple biological activities are expressed by a mouse interleukin 6 cDNA clone isolated from bone marrow stromal cells. Proc. Natl Acad. Sci. USA 85:7099.
33. Hunt, P., D Robertson, D. Weiss, D. Rennick, F. Lee, and O. N. Witte. 1987. A single bone marrow-derived stromal cell type supports the in vitro growth of early lymphoid and myeloid cells. Cell 48:997
34. Palacios, R., and M. Steinmetz. 1985. IL-3-dependent mouse clones that express B220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo Cell 41:727.
35. Rolink, A., and F. Melcher. 1993. B lymphopoiesis in the mouse. Adv Immunol. 53:123.
36. Henderson, A J., R. Narayanan, L Collins, and K. Dorshkind. 1992. Status of κL chain gene rearrangements and c-kit and IL-7 receptor expression in stromal cell-dependent pre-B cells J. Immunol. 149:1973.
37. Ogawa, M , Y. Matsuzaki, S. Nishikawa, S Hayashi, T. Kunisada, T. Sudo, T. Kina, H. Nakauchi, and S. Nishikawa. 1991. Expression and function of c-kit in hemopoietic progenitor cells. J. Exp Med. 174:63.
38. Wells, S M., A. B. Kantor, and A M. Stall. 1994. CD43 (S7) expression identifies peripheral B cell subsets. J. Immunol. 153:5503.
39. Whitlock, C. A , and O. N. Witte. 1982. Long term culture of B lymphocytes and their precursors from murine bone marrow. Proc Natl. Acad Sci. USA 79:3608.
40. Kuntsada, T , M. Ogawa, S. Hayashi, T. Era, and S. Nishikawa. 1992. Interleukin-7 and B lymphopoiesis. Chem Immunol 51:205.
41. Kierney, P. C., and K. Dorshkind. 1987. B lymphocyte precursors and myeloid progenitors survive in diffusion chamber cultures but B cell differentiation requires close association with stromal cells. Blood 70:1418.
42. Namen, A E., S. Lupton, K. Hyerrild, J. Wignall, D. Y Mochiziki, A. Schmierer, B. Mosley, C. J. March, D. Urdal, S. Gillis, D. Cosman, and R. G. Goodwin. 1988. Stimulation of B-cell progenitors by cloned murine interleukin-7. Nature 33:571.
43. Landreth, K., P. W. Kincade, G. Lee, and D. E. Harrison. 1984. B lymphocyte precursors in embryonic and adult W anemic mice. J. Immunol. 132:2724.
44. Opstelten, D , and D. G. Osmond. 1985. Regulation of pre-B cell proliferation in bone marrow: immunofluorescence stathmokinetic studies of cytoplasmic μ chain-bearing cells in anti-IgM-treated mice, hematologically deficient mutant mice and mice given sheep red blood cells Eur. J. Immunol. 15:599.
45. Williams, D. E., J. Eisenmann, A. Baird, C. Rausch, K Van Ness, C. March, L. Park, U. Martin, D. Y. Mochizuki, H. S. Boswell, G. S. Burgess, D. Cosman, and S. D. Lyman. 1990 Identification of a ligand for the c-kit proto-oncogene. Cell 63:167.
46. Zsebo, K. M., J Wypych, I. K. McKniece, H. S. Lu, A. Smith, S. B. Karkare, R. K. Sachdev, V. N Yuschenkiff, N. C. Birkett, L R. Williams, V. N. Satyagal, W Tung, R. A. Bosselman, E A. Mendiaz, and K. E. Langley. 1990 Identification, purification, and biological characterization of hematopoeitic stem cell factor from buffalo rat liver-conditioned medium. Cell 63:195.
47. Flanagan, J. G., and P. Leder 1990. The kit ligand, a cell surface molecule altered in steel mutant fibroblasts. Cell 63:185.
48. Huang, E., K. Nocka, D. R. Beier, T. Chu, J. Buck, H. Lahm, D. Wellner, P Leder, and P. Besmer. 1990. The hematopoeitc growth factor, KL is encoded at the Sl locus and it the ligand of the c-kit receptor, the gene product of the W locus. Cell 63:225.
49. Ogawa, M., S. Nishikawa, K. Ikuta, F Yamamura, M. Naito, K. Takahashi, and S. F. Nishikawa. 1988. B cell ontongeny in murine embryo studied by a culture system with the monolayer of a stromal cell clone ST2: B cell progenitor develops first in embryonal body rather than in yolk sac. EMBO J. 7:1337.
50. Peschon, J J., P J. Morrissey, K. H. Grabstein, F. J. Ramsdell, E Maraskovsky, B. C. Gliniak, L. S. Park, S. F. Ziegler, D. E Williams, C B Ware, J D Meyer, and B L. Davison 1994 Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J. Exp. Med 180:1955.
51. Hirayama, F., S. C. Clark, and M. Ogawa. 1994. Negative regulation of early B lymphopoiesis by interleukin 3 and interleukin 1α. Proc. Natl. Acad. Sci USA 91:469.