메뉴 건너뛰기




Volumn 6, Issue 8, 2000, Pages 3342-3353

Oncolytic herpes simplex virus-1 lacking ICP34.5 induces p53-independent death and is efficacious against chemotherapy-resistant ovarian cancer

Author keywords

[No Author keywords available]

Indexed keywords

CA 125 ANTIGEN; CARBOPLATIN; PACLITAXEL; PROTEIN P53; VIRUS PROTEIN;

EID: 0033875563     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (65)

References (84)
  • 1
    • 0020422578 scopus 로고
    • Thymidine kinase deletion mutants of herpes simplex virus type 1
    • Sanders, P., Wilkie, N., and Davison, A. Thymidine kinase deletion mutants of herpes simplex virus type 1. J. Gen. Virol., 63: 277-295, 1982.
    • (1982) J. Gen. Virol. , vol.63 , pp. 277-295
    • Sanders, P.1    Wilkie, N.2    Davison, A.3
  • 2
    • 0025864440 scopus 로고
    • Experimental therapy of human glioma by means of a genetically engineered virus mutant
    • Washington DC
    • Martuza, R., Malick, A., Markert, J., Ruffner, K., and Coen, D. Experimental therapy of human glioma by means of a genetically engineered virus mutant. Science (Washington DC), 252: 854-856, 1991.
    • (1991) Science , vol.252 , pp. 854-856
    • Martuza, R.1    Malick, A.2    Markert, J.3    Ruffner, K.4    Coen, D.5
  • 3
    • 0026500493 scopus 로고
    • Deletion of the herpes simplex virus type 1 ribonucleotide reductase gene alters virulence and latency in vivo
    • Idowu, A., Fraser-Smith, E., Poffenberger, K., and Herman, R. Deletion of the herpes simplex virus type 1 ribonucleotide reductase gene alters virulence and latency in vivo. Antiviral Res., 17: 145-156, 1992.
    • (1992) Antiviral Res. , vol.17 , pp. 145-156
    • Idowu, A.1    Fraser-Smith, E.2    Poffenberger, K.3    Herman, R.4
  • 5
    • 0028501457 scopus 로고
    • Antitumor activity and reporter gene transfer into rat brain neoplasms inoculated with herpes simplex virus vectors defective in thymidine kinase or ribonucleotide reductase
    • Boviatsis, E., Scharf, J., Chase, M., Harrington, K., Kowall, N., Breakefield, X., and Chiocca, E. Antitumor activity and reporter gene transfer into rat brain neoplasms inoculated with herpes simplex virus vectors defective in thymidine kinase or ribonucleotide reductase. Gene Ther., 1: 323-331, 1994.
    • (1994) Gene Ther. , vol.1 , pp. 323-331
    • Boviatsis, E.1    Scharf, J.2    Chase, M.3    Harrington, K.4    Kowall, N.5    Breakefield, X.6    Chiocca, E.7
  • 6
    • 0029680820 scopus 로고    scopus 로고
    • Enhancement of gene therapy specificity for diffuse colon carcinoma liver metastases with recombinant herpes simplex virus
    • Carroll, N., Chiocca, E., Takahashi, K., and Tanabe, K. Enhancement of gene therapy specificity for diffuse colon carcinoma liver metastases with recombinant herpes simplex virus. Ann. Surg., 224: 323-329, 1996.
    • (1996) Ann. Surg. , vol.224 , pp. 323-329
    • Carroll, N.1    Chiocca, E.2    Takahashi, K.3    Tanabe, K.4
  • 7
    • 0028931228 scopus 로고
    • Comparison of genetically engineered herpes simplex viruses for the treatment of brain tumors in a SCID mouse model of human malignant glioma
    • Chambers, R., Gillespie, G. Y., Soroceanu, L., Andreansky, S., Chatterjee, S., Chou, J., Roizman, B., and Whitley, R. J. Comparison of genetically engineered herpes simplex viruses for the treatment of brain tumors in a SCID mouse model of human malignant glioma. Proc. Natl. Acad. Sci. USA, 92: 1411-1415, 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 1411-1415
    • Chambers, R.1    Gillespie, G.Y.2    Soroceanu, L.3    Andreansky, S.4    Chatterjee, S.5    Chou, J.6    Roizman, B.7    Whitley, R.J.8
  • 9
    • 0029023868 scopus 로고
    • Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas
    • Mineta, T., Rabkin, S., Yazaki, T., Hunter, W., and Martuza, R. Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas. Nat. Med., 1: 938-943, 1995.
    • (1995) Nat. Med. , vol.1 , pp. 938-943
    • Mineta, T.1    Rabkin, S.2    Yazaki, T.3    Hunter, W.4    Martuza, R.5
  • 10
    • 0028147382 scopus 로고
    • ICP34.5 mutants of herpes simplex virus type 1 strain 17syn+ are attenuated for neurovirulence in mice and for replication in confluent primary mouse embryo cell cultures
    • Bolovan, C. A., Sawtell, N. M., and Thompson, R. L. ICP34.5 mutants of herpes simplex virus type 1 strain 17syn+ are attenuated for neurovirulence in mice and for replication in confluent primary mouse embryo cell cultures. J. Virol., 68: 48-55, 1994.
    • (1994) J. Virol. , vol.68 , pp. 48-55
    • Bolovan, C.A.1    Sawtell, N.M.2    Thompson, R.L.3
  • 11
    • 0028624704 scopus 로고
    • ICP34.5 influences herpes simplex virus type I maturation and egress from infected cells in vitro
    • Brown, S., MacLean, A., Aitken, J., and Harland, J. ICP34.5 influences herpes simplex virus type I maturation and egress from infected cells in vitro. J. Gen. Virol., 75: 3767-3686, 1994.
    • (1994) J. Gen. Virol. , vol.75 , pp. 3767-13686
    • Brown, S.1    MacLean, A.2    Aitken, J.3    Harland, J.4
  • 12
    • 0031017382 scopus 로고    scopus 로고
    • The γ(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1α to dephosphorylate the a subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-activated protein kinase
    • He, B., Gross, M., and Roizman, B. The γ(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1α to dephosphorylate the a subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-activated protein kinase. Proc. Natl. Acad. Sci. USA, 94: 843-848, 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 843-848
    • He, B.1    Gross, M.2    Roizman, B.3
  • 13
    • 0025975357 scopus 로고
    • Herpes simplex virus type 1 deletion variant 1714 and 1716 pinpoint neurovirulence-related sequences in Glasgow strain 17+ between immediate early gene 1 and the "a" sequence
    • MacLean, M., Ul-Fareed, M., Roberson, L., Harland, J., and Brown, S. Herpes simplex virus type 1 deletion variant 1714 and 1716 pinpoint neurovirulence-related sequences in Glasgow strain 17+ between immediate early gene 1 and the "a" sequence. J. Gen. Virol., 72: 631-639, 1991.
    • (1991) J. Gen. Virol. , vol.72 , pp. 631-639
    • MacLean, M.1    Ul-Fareed, M.2    Roberson, L.3    Harland, J.4    Brown, S.5
  • 14
    • 0025688373 scopus 로고
    • 1 34.5, a gene nonessential for growth in culture
    • Washington DC
    • 1 34.5, a gene nonessential for growth in culture. Science (Washington DC), 250: 1262-1265, 1990.
    • (1990) Science , vol.250 , pp. 1262-1265
    • Chou, J.1    Kern, E.2    Whitley, R.3    Roizman, B.4
  • 15
    • 0030897659 scopus 로고    scopus 로고
    • Evaluation of genetically engineered herpes simplex viruses as oncolytic agents for human malignant brain tumors
    • Andreansky, S., Soroceanu, L., Flotte, E., Chou, J., Marken, J., Gillespie, G., Roizman, B., and Whitley, R. Evaluation of genetically engineered herpes simplex viruses as oncolytic agents for human malignant brain tumors. Cancer Res., 57: 1502-1509, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 1502-1509
    • Andreansky, S.1    Soroceanu, L.2    Flotte, E.3    Chou, J.4    Marken, J.5    Gillespie, G.6    Roizman, B.7    Whitley, R.8
  • 16
    • 0029113725 scopus 로고
    • Treatment of experimental intracranial murine melanoma with a neuroattenuated herpes simplex virus 1 mutant
    • Randazzo, B., Kerasi, S., Gesser, R., Alsop, D., Ford, J., Brown, S., MacLean, A., and Fraser, N. Treatment of experimental intracranial murine melanoma with a neuroattenuated herpes simplex virus 1 mutant. Virology, 211: 94-101, 1995.
    • (1995) Virology , vol.211 , pp. 94-101
    • Randazzo, B.1    Kerasi, S.2    Gesser, R.3    Alsop, D.4    Ford, J.5    Brown, S.6    MacLean, A.7    Fraser, N.8
  • 17
    • 0028822061 scopus 로고
    • Treatment of human malignant meningiomas by G207, a replication competent multimutated herpes simplex virus 1
    • Yazaki, T., Manz, H., Rabkin, S., and Martuza, R. Treatment of human malignant meningiomas by G207, a replication competent multimutated herpes simplex virus 1. Cancer Res., 55: 4752-4756, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 4752-4756
    • Yazaki, T.1    Manz, H.2    Rabkin, S.3    Martuza, R.4
  • 18
    • 0030914772 scopus 로고    scopus 로고
    • Treatment of experimental subcutaneous human melanoma with a replication-restricted herpes simplex virus mutant
    • Randazzo, B., Bhat, M., Kesari, S., Fraser, N., and Brown, S. Treatment of experimental subcutaneous human melanoma with a replication-restricted herpes simplex virus mutant. J. Investig. Dermatol., 108: 933-937, 1997.
    • (1997) J. Investig. Dermatol. , vol.108 , pp. 933-937
    • Randazzo, B.1    Bhat, M.2    Kesari, S.3    Fraser, N.4    Brown, S.5
  • 19
    • 0033544902 scopus 로고    scopus 로고
    • Combined therapy with chemotherapeutic agents and herpes simplex virus type 1 ICP34.5 mutant (HSV-1716) in human non-small cell lung cancer
    • Toyoizumi, T., Mick, R., Abbas, A. E., Kang, E. H., Kaiser, L. R., and Molnar-Kimber, K. L. Combined therapy with chemotherapeutic agents and herpes simplex virus type 1 ICP34.5 mutant (HSV-1716) in human non-small cell lung cancer. Gene Ther., 10: 3013-3029, 2000.
    • (2000) Gene Ther. , vol.10 , pp. 3013-3029
    • Toyoizumi, T.1    Mick, R.2    Abbas, A.E.3    Kang, E.H.4    Kaiser, L.R.5    Molnar-Kimber, K.L.6
  • 21
    • 0030958391 scopus 로고    scopus 로고
    • A novel multiply mutated HSV-1 strain for the treatment of human brain tumors
    • Pyles, R. B., Warnick, R. E., Chalk, C., Szanti, B. E., and Parysek, L. A novel multiply mutated HSV-1 strain for the treatment of human brain tumors. Human Gene Ther., 8: 533-544, 1997.
    • (1997) Human Gene Ther. , vol.8 , pp. 533-544
    • Pyles, R.B.1    Warnick, R.E.2    Chalk, C.3    Szanti, B.E.4    Parysek, L.5
  • 22
    • 0028108669 scopus 로고
    • Treatment of malignant gliomas using ganciclovir-hypersensitive, ribonucleotide reductase-deficient herpes simplex viral mutant
    • Mineta, T., Rabkin, S., and Martuza, R. Treatment of malignant gliomas using ganciclovir-hypersensitive, ribonucleotide reductase-deficient herpes simplex viral mutant. Cancer Res., 54: 3963-3966, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 3963-3966
    • Mineta, T.1    Rabkin, S.2    Martuza, R.3
  • 23
    • 0032505773 scopus 로고    scopus 로고
    • Treatment of human breast cancer in a brain metastatic model by G207, a replication competent multimutated herpes simplex Virus 1
    • Toda, M., Rabkin, S. D., and Martuza, R. L. Treatment of human breast cancer in a brain metastatic model by G207, a replication competent multimutated herpes simplex Virus 1. Hum. Gene Ther., 9: 2173-2185, 1998.
    • (1998) Hum. Gene Ther. , vol.9 , pp. 2173-2185
    • Toda, M.1    Rabkin, S.D.2    Martuza, R.L.3
  • 24
    • 0032774578 scopus 로고    scopus 로고
    • Oncolytic viral therapy for human colorectal cancer and liver metastases using a multi-mutated herpes simplex virus type-1 (G207)
    • Kooby, D. A., Carew, J. F., Halterman, M. W., Mack, J. E., Bertino, J. R., Blumgart, L. H., Federoff, H. J., and Fong, Y. Oncolytic viral therapy for human colorectal cancer and liver metastases using a multi-mutated herpes simplex virus type-1 (G207). FASEB J., 13: 1325-1334, 1999.
    • (1999) FASEB J. , vol.13 , pp. 1325-1334
    • Kooby, D.A.1    Carew, J.F.2    Halterman, M.W.3    Mack, J.E.4    Bertino, J.R.5    Blumgart, L.H.6    Federoff, H.J.7    Fong, Y.8
  • 25
    • 0033166680 scopus 로고    scopus 로고
    • Selective infection and cytolysis of human head and neck squamous cell carcinoma with sparing of normal mucosa by a cytotoxic herpes simplex virus type 1 (G207)
    • Carew, J. F., Kooby, D. A., Halterman, M. W., Federoff, H. J., and Fong, Y. Selective infection and cytolysis of human head and neck squamous cell carcinoma with sparing of normal mucosa by a cytotoxic herpes simplex virus type 1 (G207). Hum. Gene Ther., 10: 1599-1606, 1999.
    • (1999) Hum. Gene Ther. , vol.10 , pp. 1599-1606
    • Carew, J.F.1    Kooby, D.A.2    Halterman, M.W.3    Federoff, H.J.4    Fong, Y.5
  • 26
    • 0033135055 scopus 로고    scopus 로고
    • Replication-competent, nonneuroinvasive genetically engineered herpes virus is highly effective in the treatment of therapy-resistant experimental human tumors
    • Advani, S. J., Chung, S. M., Yan, S. Y., Gillespie, G. Y., Markert, J. M., Whitley, R. J., Roizman, B., and Weichselbaum, R. R. Replication-competent, nonneuroinvasive genetically engineered herpes virus is highly effective in the treatment of therapy-resistant experimental human tumors. Cancer Res., 59: 2055-2058, 1999.
    • (1999) Cancer Res. , vol.59 , pp. 2055-2058
    • Advani, S.J.1    Chung, S.M.2    Yan, S.Y.3    Gillespie, G.Y.4    Markert, J.M.5    Whitley, R.J.6    Roizman, B.7    Weichselbaum, R.R.8
  • 29
    • 0003080475 scopus 로고    scopus 로고
    • Application of recombinant herpes simplex virus-1 (HSV-1) for the treatment of malignancies outside the central nervous system
    • Coukos, G., Rubin, S. C., and Molnar-Kimber, K. L. Application of recombinant herpes simplex virus-1 (HSV-1) for the treatment of malignancies outside the central nervous system. Gene Ther. Mol. Biol., 3: 78-89, 1999.
    • (1999) Gene Ther. Mol. Biol. , vol.3 , pp. 78-89
    • Coukos, G.1    Rubin, S.C.2    Molnar-Kimber, K.L.3
  • 30
    • 0034032455 scopus 로고    scopus 로고
    • Multi-attenuated herpes simplex virus-1 mutant G207 exerts cytotoxicity against epithelial ovarian cancer but not normal mesothelium and is suitable for intraperitoneal oncolytic therapy
    • Coukos, G., Makrigiannakis, A., Montas, S., Kaiser, L. R., Albelda, S. M., Rubin, S. M., and Molnar-Kimber, K. L. Multi-attenuated herpes simplex virus-1 mutant G207 exerts cytotoxicity against epithelial ovarian cancer but not normal mesothelium and is suitable for intraperitoneal oncolytic therapy. Cancer Gene Ther., 7: 275-283, 2000.
    • (2000) Cancer Gene Ther. , vol.7 , pp. 275-283
    • Coukos, G.1    Makrigiannakis, A.2    Montas, S.3    Kaiser, L.R.4    Albelda, S.M.5    Rubin, S.M.6    Molnar-Kimber, K.L.7
  • 31
    • 0030903874 scopus 로고    scopus 로고
    • Herpes simplex virus type 1 induces apoptosis in peripheral blood T lymphocytes
    • Ito, M., Watanabe, M., Kamiya, H., and Sakurai, M. Herpes simplex virus type 1 induces apoptosis in peripheral blood T lymphocytes. J. Infect. Dis., 175: 1220-1224, 1997.
    • (1997) J. Infect. Dis. , vol.175 , pp. 1220-1224
    • Ito, M.1    Watanabe, M.2    Kamiya, H.3    Sakurai, M.4
  • 32
    • 0032584081 scopus 로고    scopus 로고
    • Herpes simplex virus 1 induces and blocks apoptosis at multiple steps during infection and protects cells from exogenous inducers in a cell type-dependent manner
    • Galvan, V., and Roizman, B. Herpes simplex virus 1 induces and blocks apoptosis at multiple steps during infection and protects cells from exogenous inducers in a cell type-dependent manner. Proc. Natl. Acad. Sci. USA, 95: 3931-3936, 1998.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 3931-3936
    • Galvan, V.1    Roizman, B.2
  • 33
    • 0030878879 scopus 로고    scopus 로고
    • The herpes simplex virus 1 protein kinase Us3 is required for protection from apoptosis induced by the virus
    • Leopardi, R., van Sant, C., and Roizman, B. The herpes simplex virus 1 protein kinase Us3 is required for protection from apoptosis induced by the virus. Proc. Natl. Acad. Sci. USA, 94: 7891-7896, 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 7891-7896
    • Leopardi, R.1    Van Sant, C.2    Roizman, B.3
  • 34
    • 0032830315 scopus 로고    scopus 로고
    • Herpes simplex virus inhibits apoptosis through the action of two genes, Us5 and Us3
    • Jerome, K. R., Fox, R., Chen, Z., Sears, A. E., Lee, H., and Corey, L. Herpes simplex virus inhibits apoptosis through the action of two genes, Us5 and Us3. J. Virol., 73: 8950-8957, 1999.
    • (1999) J. Virol. , vol.73 , pp. 8950-8957
    • Jerome, K.R.1    Fox, R.2    Chen, Z.3    Sears, A.E.4    Lee, H.5    Corey, L.6
  • 35
    • 0032758642 scopus 로고    scopus 로고
    • Induction and prevention of apoptosis in human HEp-2 cells by herpes simplex virus type 1
    • Aubert, M., O'Toole, J., and Blaho, J. A. Induction and prevention of apoptosis in human HEp-2 cells by herpes simplex virus type 1. J. Virol., 73: 10359-10370, 1999.
    • (1999) J. Virol. , vol.73 , pp. 10359-10370
    • Aubert, M.1    O'Toole, J.2    Blaho, J.A.3
  • 36
    • 0345164384 scopus 로고    scopus 로고
    • Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase
    • Gale, M., Jr., and Katze, M. G. Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase. Pharmacol. Ther., 78: 29-46, 1998.
    • (1998) Pharmacol. Ther. , vol.78 , pp. 29-46
    • Gale M., Jr.1    Katze, M.G.2
  • 37
    • 0033614407 scopus 로고    scopus 로고
    • The double-stranded RNA activated protein kinase PKR physically associates with the tumor suppressor p53 protein and phosphorylates human p53 on serine 392 in vitro
    • Cuddihy, A. R., Wong, A. H., Tam, N. W., Li, S., and Koromilas, A. E. The double-stranded RNA activated protein kinase PKR physically associates with the tumor suppressor p53 protein and phosphorylates human p53 on serine 392 in vitro. Oncogene, 18: 2690-2702, 1999.
    • (1999) Oncogene , vol.18 , pp. 2690-2702
    • Cuddihy, A.R.1    Wong, A.H.2    Tam, N.W.3    Li, S.4    Koromilas, A.E.5
  • 38
    • 0032566514 scopus 로고    scopus 로고
    • Tumor suppressor p53 as a component of the tumor necrosis factor-induced, protein kinase PKR-mediated apoptotic pathway in human promonocytic U937 cells
    • Yeung, M. C., and Lau, A. S. Tumor suppressor p53 as a component of the tumor necrosis factor-induced, protein kinase PKR-mediated apoptotic pathway in human promonocytic U937 cells. J. Biol. Chem., 273: 25198-25202, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 25198-25202
    • Yeung, M.C.1    Lau, A.S.2
  • 39
    • 0028025563 scopus 로고
    • Apoptosis in cancer therapy: Crossing the threshold
    • Fisher, D. E. Apoptosis in cancer therapy: crossing the threshold. Cell, 78: 539-542, 1994.
    • (1994) Cell , vol.78 , pp. 539-542
    • Fisher, D.E.1
  • 40
    • 0030998763 scopus 로고    scopus 로고
    • Role of oncogenes in resistance and killing by cancer therapeutic agents
    • el-Deiry, W. S. Role of oncogenes in resistance and killing by cancer therapeutic agents. Curr. Opin. Oncol., 9: 79-87, 1997.
    • (1997) Curr. Opin. Oncol. , vol.9 , pp. 79-87
    • El-Deiry, W.S.1
  • 42
    • 0031970615 scopus 로고    scopus 로고
    • Chemotherapy resistance in ovarian cancer; new molecular perspectives
    • Coukos, G., and Rubin, S. Chemotherapy resistance in ovarian cancer; new molecular perspectives. Obstet. Gynecol., 9: 783-792, 1998.
    • (1998) Obstet. Gynecol. , vol.9 , pp. 783-792
    • Coukos, G.1    Rubin, S.2
  • 43
    • 0032414270 scopus 로고    scopus 로고
    • Physiologic and pathologic drug resistance in ovarian carcinoma - A hypothesis based on a clonal progression model
    • Pusztai, L., Siddik, Z. H., Mills, G. B., and Bast, R. C., Jr. Physiologic and pathologic drug resistance in ovarian carcinoma - a hypothesis based on a clonal progression model. Acta Oncol., 37: 629-640, 1998.
    • (1998) Acta Oncol. , vol.37 , pp. 629-640
    • Pusztai, L.1    Siddik, Z.H.2    Mills, G.B.3    Bast R.C., Jr.4
  • 44
    • 0027472165 scopus 로고
    • Mechanisms of drug resistance in ovarian cancer
    • Phila.
    • Johnson, S. W., Ozols, R. F., and Hamilton, T. C. Mechanisms of drug resistance in ovarian cancer. Cancer (Phila.), 71: 644-649, 1993.
    • (1993) Cancer , vol.71 , pp. 644-649
    • Johnson, S.W.1    Ozols, R.F.2    Hamilton, T.C.3
  • 45
    • 0031581815 scopus 로고    scopus 로고
    • Acquisition of Taxol resistance via P-glycoprotein- and non-P-glycoprotein-mediated mechanisms in human ovarian carcinoma cells
    • Parekh, H., Wiesen, K., and Simpkins, H. Acquisition of Taxol resistance via P-glycoprotein- and non-P-glycoprotein-mediated mechanisms in human ovarian carcinoma cells. Biochem. Pharmacol., 53: 461-470, 1997.
    • (1997) Biochem. Pharmacol. , vol.53 , pp. 461-470
    • Parekh, H.1    Wiesen, K.2    Simpkins, H.3
  • 46
    • 0026760566 scopus 로고
    • Abnormal structure and expression of the p53 gene in human ovarian carcinoma cell lines
    • Yaginuma, Y., and Westphal, H. Abnormal structure and expression of the p53 gene in human ovarian carcinoma cell lines. Cancer Res., 52: 4196-4199, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 4196-4199
    • Yaginuma, Y.1    Westphal, H.2
  • 47
    • 0031127927 scopus 로고    scopus 로고
    • Apoptosis as a measure of chemosensitivity to cisplatin and taxol therapy in ovarian cancer cell lines
    • Gibb, R. K., Taylor, D. D., Wan, T., O'Connor, D. M., Doering, D. L., and Gercel-Taylor, C. Apoptosis as a measure of chemosensitivity to cisplatin and taxol therapy in ovarian cancer cell lines. Gynecol. Oncol., 65: 13-22, 1997.
    • (1997) Gynecol. Oncol. , vol.65 , pp. 13-22
    • Gibb, R.K.1    Taylor, D.D.2    Wan, T.3    O'Connor, D.M.4    Doering, D.L.5    Gercel-Taylor, C.6
  • 48
    • 0028326742 scopus 로고
    • Role of platinum-DNA adduct formation and removal in cisplatin resistance in human ovarian cancer cell lines
    • Johnson, S. W., Perez, R. P., Godwin, A. K., Yeung, A. T., Handel, L. M., Ozols, R. F., and Hamilton, T. C. Role of platinum-DNA adduct formation and removal in cisplatin resistance in human ovarian cancer cell lines. Biochem. Pharmacol., 47: 689-697, 1994.
    • (1994) Biochem. Pharmacol. , vol.47 , pp. 689-697
    • Johnson, S.W.1    Perez, R.P.2    Godwin, A.K.3    Yeung, A.T.4    Handel, L.M.5    Ozols, R.F.6    Hamilton, T.C.7
  • 49
    • 0031873441 scopus 로고    scopus 로고
    • Characterisation of the p53 status, BCL-2 expression and radiation and platinum drug sensitivity of a panel of human ovarian cancer cell lines
    • Pestell, K. E., Medlow, C. J., Titley, J. C., Kelland, L. R., and Walton, M. I. Characterisation of the p53 status, BCL-2 expression and radiation and platinum drug sensitivity of a panel of human ovarian cancer cell lines. Int. J. Cancer, 77: 913-918, 1998.
    • (1998) Int. J. Cancer , vol.77 , pp. 913-918
    • Pestell, K.E.1    Medlow, C.J.2    Titley, J.C.3    Kelland, L.R.4    Walton, M.I.5
  • 50
    • 0031311480 scopus 로고    scopus 로고
    • Sensitization of cis-platinum by a recombinant adenovirus vector expressing wild-type p53 gene in human ovarian carcinomas
    • Song, K., Li, Z., Seth, P., Cowan, K. H., and Sinha, B. K. Sensitization of cis-platinum by a recombinant adenovirus vector expressing wild-type p53 gene in human ovarian carcinomas. Oncol. Res., 9: 603-609, 1997.
    • (1997) Oncol. Res. , vol.9 , pp. 603-609
    • Song, K.1    Li, Z.2    Seth, P.3    Cowan, K.H.4    Sinha, B.K.5
  • 52
    • 0030094571 scopus 로고    scopus 로고
    • p53 and chemosensitivity
    • Wu, G. S., and El-Deiry, W. S. p53 and chemosensitivity. Nat. Med., 2: 255-256, 1996.
    • (1996) Nat. Med. , vol.2 , pp. 255-256
    • Wu, G.S.1    El-Deiry, W.S.2
  • 53
    • 0025639158 scopus 로고
    • The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
    • Scheffner, M., Werness, B. A., Huibregtse, J. M., Levine, A. J., and Howley, P. M. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell, 63: 1129-1136, 1990.
    • (1990) Cell , vol.63 , pp. 1129-1136
    • Scheffner, M.1    Werness, B.A.2    Huibregtse, J.M.3    Levine, A.J.4    Howley, P.M.5
  • 55
    • 0031036984 scopus 로고    scopus 로고
    • Cytometry in cell necrobiology: Analysis of apoptosis and accidental cell death (necrosis)
    • Darzynkiewicz, Z., Juan, G., Li, X., Gorczyca, W., Murakami, T., and Traganos, F. Cytometry in cell necrobiology: analysis of apoptosis and accidental cell death (necrosis). Cytometry, 27: 1-20, 1997.
    • (1997) Cytometry , vol.27 , pp. 1-20
    • Darzynkiewicz, Z.1    Juan, G.2    Li, X.3    Gorczyca, W.4    Murakami, T.5    Traganos, F.6
  • 57
    • 0032519582 scopus 로고    scopus 로고
    • Independent pathways of p53 induction by cisplatin and X-rays in a cisplatin-resistant ovarian tumor cell line
    • Siddik, Z. H., Mims, B., Lozano, G., and Thai, G. Independent pathways of p53 induction by cisplatin and X-rays in a cisplatin-resistant ovarian tumor cell line. Cancer Res., 58: 698-703, 1998.
    • (1998) Cancer Res. , vol.58 , pp. 698-703
    • Siddik, Z.H.1    Mims, B.2    Lozano, G.3    Thai, G.4
  • 58
    • 0031626830 scopus 로고    scopus 로고
    • DNA binding activities of p53 protein following cisplatin damage of ovarian cells
    • Wetzel, C. C., and Berberich, S. J. DNA binding activities of p53 protein following cisplatin damage of ovarian cells. Oncol Res., 10: 151-161, 1998.
    • (1998) Oncol Res. , vol.10 , pp. 151-161
    • Wetzel, C.C.1    Berberich, S.J.2
  • 59
    • 0031920710 scopus 로고    scopus 로고
    • Induction of apoptosis by Taxol and cisplatin and effect on cell cycle-related proteins in cisplatin-sensitive and -resistant human ovarian cells
    • Zaffaroni, N., Silvestrini, R., Orlandi, L., Bearzatto, A., Gornati, D., and Villa, R. Induction of apoptosis by Taxol and cisplatin and effect on cell cycle-related proteins in cisplatin-sensitive and -resistant human ovarian cells. Br. J. Cancer, 77: 1378-1385, 1998.
    • (1998) Br. J. Cancer , vol.77 , pp. 1378-1385
    • Zaffaroni, N.1    Silvestrini, R.2    Orlandi, L.3    Bearzatto, A.4    Gornati, D.5    Villa, R.6
  • 60
    • 0031747118 scopus 로고    scopus 로고
    • Cisplatin- and paclitaxel-induced apoptosis of ovarian carcinoma cells and the relationship between bax and bak up-regulation and the functional status of p53
    • Jones, N. A., Turner, J., McIlwrath, A. J., Brown, R., and Dive, C. Cisplatin- and paclitaxel-induced apoptosis of ovarian carcinoma cells and the relationship between bax and bak up-regulation and the functional status of p53. Mol. Pharmacol., 53: 819-826, 1998.
    • (1998) Mol. Pharmacol. , vol.53 , pp. 819-826
    • Jones, N.A.1    Turner, J.2    McIlwrath, A.J.3    Brown, R.4    Dive, C.5
  • 61
    • 0030938089 scopus 로고    scopus 로고
    • Bax deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis
    • McCurrach, M. E., Connor, T. M., Knudson, C. M., Korsmeyer, S. J., and Lowe, S. W. bax deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis. Proc. Natl. Acad. Sci. USA, 94: 2345-2349, 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 2345-2349
    • McCurrach, M.E.1    Connor, T.M.2    Knudson, C.M.3    Korsmeyer, S.J.4    Lowe, S.W.5
  • 63
    • 0028927179 scopus 로고
    • p53, cell cycle control and apoptosis: Implications for cancer
    • Kastan, M. B., Canman, C. E., and Leonard, C. J. p53, cell cycle control and apoptosis: implications for cancer. Cancer Metastasis Rev., 14: 3-15, 1995.
    • (1995) Cancer Metastasis Rev. , vol.14 , pp. 3-15
    • Kastan, M.B.1    Canman, C.E.2    Leonard, C.J.3
  • 65
    • 0032947716 scopus 로고    scopus 로고
    • Combined cytotoxic effects of tumor necrosis factor-α with various cytotoxic agents in tumor cell lines that are drug resistant due to mutated p53
    • Sleijfer, S., Le, T. K., de Jong, S., Timmer-Bosscha, H., Withoff, S., and Mulder, N. H. Combined cytotoxic effects of tumor necrosis factor-α with various cytotoxic agents in tumor cell lines that are drug resistant due to mutated p53. J. Immunother., 22: 48-53, 1999.
    • (1999) J. Immunother. , vol.22 , pp. 48-53
    • Sleijfer, S.1    Le, T.K.2    De Jong, S.3    Timmer-Bosscha, H.4    Withoff, S.5    Mulder, N.H.6
  • 66
    • 0030745894 scopus 로고    scopus 로고
    • Mechanism of resistance to cisplatin in a human ovarian carcinoma cell line selected for resistance to doxorubicin: Possible role of p53
    • Vikhanskaya, F., Clerico, L., Valenti, M., Stanzione, M. S., Broggini, M., Parodi, S., and Russo, P. Mechanism of resistance to cisplatin in a human ovarian carcinoma cell line selected for resistance to doxorubicin: possible role of p53. Int. J. Cancer, 72: 155-159, 1997.
    • (1997) Int. J. Cancer , vol.72 , pp. 155-159
    • Vikhanskaya, F.1    Clerico, L.2    Valenti, M.3    Stanzione, M.S.4    Broggini, M.5    Parodi, S.6    Russo, P.7
  • 67
    • 0030026934 scopus 로고    scopus 로고
    • Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis
    • Wahl, A. F., Donaldson, K. L., Fairchild, C., Lee, F. Y., Foster, S. A., Demers, G. W., and Galloway, D. A. Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis. Nat. Med., 2: 72-79, 1996.
    • (1996) Nat. Med. , vol.2 , pp. 72-79
    • Wahl, A.F.1    Donaldson, K.L.2    Fairchild, C.3    Lee, F.Y.4    Foster, S.A.5    Demers, G.W.6    Galloway, D.A.7
  • 68
    • 0029155714 scopus 로고
    • Accumulation of p53 protein as a possible predictor of response to adjuvant combination chemotherapy with cyclophosphamide, methotrexate, fluorouracil, and prednisone for breast cancer
    • Elledge, R. M., Gray, R., Mansour, E., Yu, Y., Clark, G. M., Ravdin, P., Osborne, C. K., Gilchrist, K., Davidson, N. E., Robert, N., et al. Accumulation of p53 protein as a possible predictor of response to adjuvant combination chemotherapy with cyclophosphamide, methotrexate, fluorouracil, and prednisone for breast cancer. J. Natl. Cancer Inst., 87: 1254-1256, 1995.
    • (1995) J. Natl. Cancer Inst. , vol.87 , pp. 1254-1256
    • Elledge, R.M.1    Gray, R.2    Mansour, E.3    Yu, Y.4    Clark, G.M.5    Ravdin, P.6    Osborne, C.K.7    Gilchrist, K.8    Davidson, N.E.9    Robert, N.10
  • 69
    • 0028231586 scopus 로고
    • Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wild-type p53 gene
    • Fujiwara, T., Grimm, E. A., Mukhopadhyay, T., Zhang, W. W., Owen-Schaub, L. B., and Roth, J. A. Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wild-type p53 gene. Cancer Res., 54: 2287-2291, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 2287-2291
    • Fujiwara, T.1    Grimm, E.A.2    Mukhopadhyay, T.3    Zhang, W.W.4    Owen-Schaub, L.B.5    Roth, J.A.6
  • 71
    • 0030865104 scopus 로고    scopus 로고
    • Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents
    • O'Connor, P. M., Jackman, J., Bae, I., Myers, T. G., Fan, S., Mutoh, M., Scudiero, D. A., Monks, A., Sausville, E. A., Weinstein, J. N., Friend, S., Fornace, A. J., Jr., and Kohn, K. W. Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents. Cancer Res., 57: 4285-4300, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 4285-4300
    • O'Connor, P.M.1    Jackman, J.2    Bae, I.3    Myers, T.G.4    Fan, S.5    Mutoh, M.6    Scudiero, D.A.7    Monks, A.8    Sausville, E.A.9    Weinstein, J.N.10    Friend, S.11    Fornace A.J., Jr.12    Kohn, K.W.13
  • 72
    • 0033053944 scopus 로고    scopus 로고
    • p53-oriented cancer therapies: Current progress
    • Gallagher, W. M., and Brown, R. p53-oriented cancer therapies: current progress. Ann. Oncol., 10: 139-150, 1999.
    • (1999) Ann. Oncol. , vol.10 , pp. 139-150
    • Gallagher, W.M.1    Brown, R.2
  • 74
    • 0030917202 scopus 로고    scopus 로고
    • ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents
    • Heise, C., Sampson-Johannes, A., Williams, A., McCormick, F., Von Hoff, D. D., and Kirn, D. H. ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents. Nat. Med., 3: 639-645, 1997.
    • (1997) Nat. Med. , vol.3 , pp. 639-645
    • Heise, C.1    Sampson-Johannes, A.2    Williams, A.3    McCormick, F.4    Von Hoff, D.D.5    Kirn, D.H.6
  • 75
    • 0031759169 scopus 로고    scopus 로고
    • ONYX-015: Clinical data are encouraging
    • Kirn, D., Hermiston, T., and McCormick, F. ONYX-015: clinical data are encouraging. Nat. Med., 4: 1341-1342, 1998.
    • (1998) Nat. Med. , vol.4 , pp. 1341-1342
    • Kirn, D.1    Hermiston, T.2    McCormick, F.3
  • 76
    • 0032600336 scopus 로고    scopus 로고
    • Influence of p53 on herpes simplex virus type 1 vectors for cancer gene therapy
    • Yoon, S. S., Carroll, N. M., Chiocca, E. A., and Tanabe, K. K. Influence of p53 on herpes simplex virus type 1 vectors for cancer gene therapy. J. Gastrointest. Surg., 3: 34-48, 1999.
    • (1999) J. Gastrointest. Surg. , vol.3 , pp. 34-48
    • Yoon, S.S.1    Carroll, N.M.2    Chiocca, E.A.3    Tanabe, K.K.4
  • 77
    • 0033140039 scopus 로고    scopus 로고
    • Replication-competent herpes simplex virus vector G207/cisplatin combination therapy for head and neck cancer
    • Chahlavi, A., Todo, T., Martuza, R. L., and Rabkin, S. D. Replication-competent herpes simplex virus vector G207/cisplatin combination therapy for head and neck cancer. Neoplasia, 1: 162-169, 1999.
    • (1999) Neoplasia , vol.1 , pp. 162-169
    • Chahlavi, A.1    Todo, T.2    Martuza, R.L.3    Rabkin, S.D.4
  • 78
    • 0030671324 scopus 로고    scopus 로고
    • Induction of apoptosis by herpes simplex virus type 1
    • Koyama, A., and Adachi, A. Induction of apoptosis by herpes simplex virus type 1. J. Gen. Virol., 78: 2909-2912, 1997.
    • (1997) J. Gen. Virol. , vol.78 , pp. 2909-2912
    • Koyama, A.1    Adachi, A.2
  • 79
    • 0030796810 scopus 로고    scopus 로고
    • Apoptosis of cord blood T lymphocytes by herpes simplex virus type 1
    • Ito, M., Koide, W., Watanabe, M., Kamiya, H., and Sakurai, M. Apoptosis of cord blood T lymphocytes by herpes simplex virus type 1. J. Gen. Virol., 78: 1971-1975, 1997.
    • (1997) J. Gen. Virol. , vol.78 , pp. 1971-1975
    • Ito, M.1    Koide, W.2    Watanabe, M.3    Kamiya, H.4    Sakurai, M.5
  • 80
    • 0033920385 scopus 로고    scopus 로고
    • Bcl-2 blocks a caspase-dependent pathway of apoptosis activated by herpes simplex virus 1 infection in Hep-2 cells
    • Galvan, V., Brandimarti, R., Munger, J., and Roizman, B. Bcl-2 blocks a caspase-dependent pathway of apoptosis activated by herpes simplex virus 1 infection in Hep-2 cells. J. Virol., 74: 1931-1938, 2000.
    • (2000) J. Virol. , vol.74 , pp. 1931-1938
    • Galvan, V.1    Brandimarti, R.2    Munger, J.3    Roizman, B.4
  • 81
    • 0033050202 scopus 로고    scopus 로고
    • Herpes simplex virus 1 blocks caspase-3-independent and caspase-dependent pathways to cell death
    • Galvan, V., Brandimarti, R., and Roizman, B. Herpes simplex virus 1 blocks caspase-3-independent and caspase-dependent pathways to cell death. J. Virol., 73: 3219-3226, 1999.
    • (1999) J. Virol. , vol.73 , pp. 3219-3226
    • Galvan, V.1    Brandimarti, R.2    Roizman, B.3
  • 84
    • 0028085566 scopus 로고
    • Cell type and cell state determine differential in vitro growth of non-neurovirulent ICP34.5-negative herpes simplex virus types 1 and 2
    • Brown, S. M., Harland, J., MacLean, A. R., Podlech, J., and Clements, J. B. Cell type and cell state determine differential in vitro growth of non-neurovirulent ICP34.5-negative herpes simplex virus types 1 and 2. J. Gen. Virol., 75: 2367-2377, 1994.
    • (1994) J. Gen. Virol. , vol.75 , pp. 2367-2377
    • Brown, S.M.1    Harland, J.2    MacLean, A.R.3    Podlech, J.4    Clements, J.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.