In vivo production of cytokines and β (C-C) chemokines in human recurrent herpes simplex lesions - Do herpes simplex virus - Infected keratinocytes contribute to their production?

Journal of Infectious Diseases

Volumn 177, Issue 4, 1998, Pages 827-838

  Mikloska, Zorka ^a   Danis, Vic A ^b   Adams, Susan ^b   Lloyd, Andrew R ^b   Adrian, Deborah L ^b   Cunningham, Anthony L ^b  

^a WESTMEAD HOSPITAL   (Australia)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CHEMOKINE; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; RANTES;

ADULT; ARTICLE; CONTROLLED STUDY; HERPES SIMPLEX; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; INTERFERON PRODUCTION; KERATINOCYTE; LYMPHOCYTE ACTIVATION; MACROPHAGE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTEIN SECRETION; VIRUS CELL INTERACTION;

EID: 0031957982     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/515236     Document Type: Article

References (15)

1. Schmid DS, Rouse BT. The role of T cell immunity in control of herpes simplex virus. In: Rouse BT, ed. Herpes simplex virus. Pathogenesis, immunobiology and control. Berlin: Springer-Verlag, 1992:57-75.
2. Cunningham AL, Turner RR, Miller AC, Para MF, Merigan TC. Evolution of recurrent herpes simplex lesions: an immunohistologic study. J Clin Invest 1985:75:226-33.
3. Cunningham AL, Merigan TC.γ-interferon production appears to predict time of recurrence of herpes labialis. J Immunol 1983;130:2397-400.
4. Mikloska Z, Kesson AM, Penfold MET, Cunningham AL. Herpes simplex virus protein targets for CD4 and CDS lymphocyte cytotoxicity in cultured epidermal keratinocytes treated with interferon-γ. J Infect Dis 1996;173:7-17.
5. Koelle D, Posavad C, Johnson M, Ekstrom A, Corey L. Resolution of recurrent HSV-2 infection is temporally correlated with infiltration of cytotoxic lymphocytes [abstract 359]. In: Program and abstracts of the 21st Herpesvirus Workshop (DeKalb, IL). Chicago: Northern Illinois University, 1996.
6. Koelle DM, Abbo H, Peck A, Ziegweid K, Corey L. Direct recovery of herpes simplex virus (HSV)-specific T-lymphocyte clones from recurrent genital HSV-2 lesions. J Infect Dis 1994;169:956-61.
7. + T cell clones recovered from recurrent genital herpes simplex virus type 2 lesions. J Virol 1994;68:2803-10.
8. + T cells in response to MIP-lα and MIP-lβ. Science 1993;260:355-8.
9. Mosmann TR, Coffman RL. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989;7:145-73.
10. Trinchieri G. Interleukin 12 and its role in the generation of the Th1 cells. Immunol Today 1993;14:335-8.
11. Van Voorhis WC, Kaplan G, Nunes-Samo E, et al. The cutaneous infiltrates of leprosy. Cellular characteristics and the predominant T-cell phenotypes. N Engl J Med 1982;26:1593-7.
12. Matsue H, Cruz PD, Bergstresser PR, Takashima A. Cytokine expression by epidermal cell subpopulations. J Invest Dermatol 1992;99:42S-5S.
13. '3. Luger TA, Schwarz RR. Epidermal cytokines. In: Bos J, ed. Skin immune system. Boca Raton, FL: CRC Press, 1990:257-91.
14. Blauvelt A, Asada H, Klaus-Kovtun V, Altman DJ, Lucey DR, Katz SI. Interleukin 15 mRNA is expressed by human keratinocytes, Langerhans' cells, and blood-derived dendritic cells and is downregulated by ultraviolet B radiation. J Invest Dermatol 1996;106:1047-52.
15. Kang K, Kubin M, Cooper KD, Lessin SR, Trinchieri G, Rook AH. IL-12 synthesis by human Langerhans' cells. J Immunol 1996;156: 1402-7.