Metabolic manipulators: A well founded strategy to combat mitochondrial dysfunction

Journal of Inherited Metabolic Disease

Volumn 34, Issue 2, 2011, Pages 315-325

  Koene, Saskia ^a   Smeitink, Jan ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; 7 CHLORO 5 (2 CHLOROPHENYL) 1,5 DIHYDRO 4,1 BENZOTHIAZEPIN 2(3H) ONE; ALPHA TOCOPHEROL; ANTIOXIDANT; EBSELEN; FRATAXIN; GLUTATHIONE; GRAMICIDIN S; IDEBENONE; MITOQUINONE; N TERT BUTYL ALPHA PHENYLNITRONE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PLASTOQUINONE; POLYPHENOL DERIVATIVE; QUERCETIN; QUINONE DERIVATIVE; REACTIVE OXYGEN METABOLITE; TOCOPHEROL; TROLOX C; UBIDECARENONE; UNCLASSIFIED DRUG; VITAMIN;

ANTIOXIDANT ACTIVITY; CALCIUM HOMEOSTASIS; CELL METABOLISM; CLINICAL FEATURE; DIET THERAPY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG EFFECT; DRUG MECHANISM; DRUG MEGADOSE; FRIEDREICH ATAXIA; GENERAL CONDITION IMPROVEMENT; GENETIC MANIPULATION; HOMEOSTASIS; HUMAN; LEBER HEREDITARY OPTIC NEUROPATHY; LIFESTYLE MODIFICATION; LIPID PEROXIDATION; MEMBRANE POTENTIAL; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE PHOSPHORYLATION UNCOUPLING; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PROTEIN FUNCTION; REVIEW; TRANSCRIPTION REGULATION;

ANIMALS; ANTIOXIDANTS; CALCIUM; GENE EXPRESSION REGULATION; HOMEOSTASIS; HUMANS; LIPID PEROXIDATION; MEMBRANE POTENTIALS; MITOCHONDRIA; MITOCHONDRIAL DISEASES; MODELS, BIOLOGICAL; OXIDATIVE PHOSPHORYLATION; OXYGEN; REACTIVE OXYGEN SPECIES; TRANSCRIPTION, GENETIC;

EID: 79955713385     PISSN: 01418955     EISSN: 15732665     Source Type: Journal    
DOI: 10.1007/s10545-010-9162-y     Document Type: Review

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