메뉴 건너뛰기




Volumn 64, Issue 3, 2004, Pages 985-993

Energy Substrate Modulates Mitochondrial Structure and Oxidative Capacity in Cancer Cells

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; MITOCHONDRIAL DNA;

EID: 0842325793     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-03-1101     Document Type: Article
Times cited : (665)

References (51)
  • 1
    • 0035119337 scopus 로고    scopus 로고
    • Causes and consequences of hypoxia and acidity in tumour microenvironments
    • Griffiths, J. R. Causes and consequences of hypoxia and acidity in tumour microenvironments. Bioessays, 23: 295-296, 2001.
    • (2001) Bioessays , vol.23 , pp. 295-296
    • Griffiths, J.R.1
  • 2
    • 0018386209 scopus 로고
    • Evidence that glutamine, not sugar, is the major energy source for cultured Hela cells
    • Reitzer, L., Wice, B., and Kennel, D. Evidence that glutamine, not sugar, is the major energy source for cultured Hela cells. J. Biol. Chem., 254: 2669-2676, 1979.
    • (1979) J. Biol. Chem. , vol.254 , pp. 2669-2676
    • Reitzer, L.1    Wice, B.2    Kennel, D.3
  • 4
    • 0017841405 scopus 로고
    • Tumor mitochondria and the bioenergetic of cancer cells
    • J. R. Bertino (ed.). New York: Karger
    • Pedersen, P. Tumor mitochondria and the bioenergetic of cancer cells. In: J. R. Bertino (ed.), Progress in Experimental Tumor Research, Vol. 22, pp. 190-274. New York: Karger, 1978.
    • (1978) Progress in Experimental Tumor Research , vol.22 , pp. 190-274
    • Pedersen, P.1
  • 6
    • 0018875899 scopus 로고
    • Comparative study of the cytoplasmic organelles of epithelial cell lines derived from human carcinomas and nonmalignant tissues
    • Springer, E. Comparative study of the cytoplasmic organelles of epithelial cell lines derived from human carcinomas and nonmalignant tissues. Cancer Res., 40: 803-817, 1980.
    • (1980) Cancer Res. , vol.40 , pp. 803-817
    • Springer, E.1
  • 7
    • 0016574783 scopus 로고
    • Is there a role for mitochondrial genes in carcinogenesis?
    • Hoberman, H. Is there a role for mitochondrial genes in carcinogenesis? Cancer Res., 35: 3332-3335, 1975.
    • (1975) Cancer Res. , vol.35 , pp. 3332-3335
    • Hoberman, H.1
  • 9
    • 0018193223 scopus 로고
    • Differences in total mitochondrial proteins and proteins synthesized by mitochondria from rat liver and Morris hepatomas 9618A, 5123C, and 5123tc
    • Irwin, C., Malkin, L., and Morris, H. Differences in total mitochondrial proteins and proteins synthesized by mitochondria from rat liver and Morris hepatomas 9618A, 5123C, and 5123tc. Cancer Res., 38: 1584-1588, 1978.
    • (1978) Cancer Res. , vol.38 , pp. 1584-1588
    • Irwin, C.1    Malkin, L.2    Morris, H.3
  • 10
    • 0016734823 scopus 로고
    • A comparative study of inner membrane enzymes and transport systems in mitochondria from R3230AC mammary tumor and normal rat mammary gland
    • Senior, A., McGowan, S., and Hilf, R. A comparative study of inner membrane enzymes and transport systems in mitochondria from R3230AC mammary tumor and normal rat mammary gland. Cancer Res., 35: 2061-2067, 1975.
    • (1975) Cancer Res. , vol.35 , pp. 2061-2067
    • Senior, A.1    McGowan, S.2    Hilf, R.3
  • 11
    • 0018818386 scopus 로고
    • Characteristics of mitochondria isolated by rate zonal centrifugation from normal liver and Novikoff hepatomas
    • Stocco, D., and Hutson, J. Characteristics of mitochondria isolated by rate zonal centrifugation from normal liver and Novikoff hepatomas. Cancer Res., 40: 1486-1492, 1980.
    • (1980) Cancer Res. , vol.40 , pp. 1486-1492
    • Stocco, D.1    Hutson, J.2
  • 12
    • 0029018603 scopus 로고
    • Impairment of the mitochondrial respiratory chain activity in diethylnitrosamine-induced rat hepatomas: Possible involvement of oxygen free radicals
    • Boitier, E., Merad-Boudia, M., Guguen-Guillouzo, C., Defer, N., Ceballos-Picot, I., Leroux, J., and Marsac, C. Impairment of the mitochondrial respiratory chain activity in diethylnitrosamine-induced rat hepatomas: possible involvement of oxygen free radicals. Cancer Res., 55: 3028-3035, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 3028-3035
    • Boitier, E.1    Merad-Boudia, M.2    Guguen-Guillouzo, C.3    Defer, N.4    Ceballos-Picot, I.5    Leroux, J.6    Marsac, C.7
  • 13
    • 0036121875 scopus 로고    scopus 로고
    • Cultivation in glucose-deprived medium stimulates mitochondrial biogenesis and oxidative metabolism in HepG2 hepatoma cells
    • Weber, K., Ridderskamp, D., Alfert, M., Hoyer, S., and Wiesner, R. J. Cultivation in glucose-deprived medium stimulates mitochondrial biogenesis and oxidative metabolism in HepG2 hepatoma cells. Biol Chem., 383: 283-290, 2002.
    • (2002) Biol Chem. , vol.383 , pp. 283-290
    • Weber, K.1    Ridderskamp, D.2    Alfert, M.3    Hoyer, S.4    Wiesner, R.J.5
  • 14
    • 0031763886 scopus 로고    scopus 로고
    • Pyruvate kinase and the interaction of amino acid and carbohydrate metabolism in solid tumors
    • Eigenbrodt, E., Kallinowski, F., Ott, M., Mazurek, S., and Vaupel, P. Pyruvate kinase and the interaction of amino acid and carbohydrate metabolism in solid tumors. Anticancer Res., 18: 3267-3274, 1998.
    • (1998) Anticancer Res. , vol.18 , pp. 3267-3274
    • Eigenbrodt, E.1    Kallinowski, F.2    Ott, M.3    Mazurek, S.4    Vaupel, P.5
  • 15
    • 0021044454 scopus 로고
    • Dormancy versus extinction of mouse Leydig cell tumors following endocrine-induced regression
    • Huseby, R. Dormancy versus extinction of mouse Leydig cell tumors following endocrine-induced regression. Cancer Res., 43: 5365-5378, 1983.
    • (1983) Cancer Res. , vol.43 , pp. 5365-5378
    • Huseby, R.1
  • 16
    • 0026338730 scopus 로고
    • Effect of antitumor diarylsulfonylureas on in vivo and in vitro mitochondrial structure and functions
    • Thakar, J., Chapin, C., Berg, R., Ashmun, R., and Houghton, P. Effect of antitumor diarylsulfonylureas on in vivo and in vitro mitochondrial structure and functions. Cancer Res., 51: 6286-6291, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 6286-6291
    • Thakar, J.1    Chapin, C.2    Berg, R.3    Ashmun, R.4    Houghton, P.5
  • 18
    • 0033609034 scopus 로고    scopus 로고
    • Structural and spectral response of green fluorescent protein variants to changes in pH
    • Elsliger, M. A., Wachter, R. M., Hanson, G. T., Kallio, K., and Remington, S. J. Structural and spectral response of green fluorescent protein variants to changes in pH. Biochemistry, 38: 5296-301, 1999.
    • (1999) Biochemistry , vol.38 , pp. 5296-5301
    • Elsliger, M.A.1    Wachter, R.M.2    Hanson, G.T.3    Kallio, K.4    Remington, S.J.5
  • 19
    • 0032499784 scopus 로고    scopus 로고
    • Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins
    • Llopis, J., McCaffery, J. M., Miyawaki, A., Farquhar, M. G., and Tsien, R. Y. Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins. Proc. Natl. Acad. Sci. USA, 95: 6803-6808, 1998.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 6803-6808
    • Llopis, J.1    McCaffery, J.M.2    Miyawaki, A.3    Farquhar, M.G.4    Tsien, R.Y.5
  • 20
    • 0842344106 scopus 로고    scopus 로고
    • Investigating mitochondrial redox potential with redox-sensitive green fluorescent protein indicators
    • in press
    • Hanson, G. T., Aggeler, R., Oglesbee, D., Capaldi, R. A., Tsien, R. Y., and Remington, S. J. Investigating mitochondrial redox potential with redox-sensitive green fluorescent protein indicators. J. Biol. Chem., in press, 2004.
    • (2004) J. Biol. Chem.
    • Hanson, G.T.1    Aggeler, R.2    Oglesbee, D.3    Capaldi, R.A.4    Tsien, R.Y.5    Remington, S.J.6
  • 21
    • 0035502932 scopus 로고    scopus 로고
    • Shedding light on disulfide bond formation: Engineering a redox switch in green fluorescent protein
    • Ostergaard, H., Henriksen, A., Hansen, F. G., and Winther, J. R. Shedding light on disulfide bond formation: engineering a redox switch in green fluorescent protein. EMBO J., 20: 5853-5862, 2001.
    • (2001) EMBO J. , vol.20 , pp. 5853-5862
    • Ostergaard, H.1    Henriksen, A.2    Hansen, F.G.3    Winther, J.R.4
  • 22
    • 0040374467 scopus 로고    scopus 로고
    • Antibody-based approaches to diagnosis and characterization of oxidative phosphorylation diseases
    • Hanson, B., Marusich, M., and Capaldi, R. antibody-based approaches to diagnosis and characterization of oxidative phosphorylation diseases. Mitochondrion, 1: 237-248, 2001.
    • (2001) Mitochondrion , vol.1 , pp. 237-248
    • Hanson, B.1    Marusich, M.2    Capaldi, R.3
  • 23
    • 0035937748 scopus 로고    scopus 로고
    • Human complex 1 defects can be resolved by monoclonal antibody analysis into distinct subunit assembly patterns
    • Triepels, R., Hanson, B., van den Heuvel, L., Sundell, L., Marusich, M., Smeitink, J., and Capaldi, R. Human complex 1 defects can be resolved by monoclonal antibody analysis into distinct subunit assembly patterns. J. Biol. Chem., 276: 8892-8897, 2001.
    • (2001) J. Biol. Chem. , vol.276 , pp. 8892-8897
    • Triepels, R.1    Hanson, B.2    Van Den Heuvel, L.3    Sundell, L.4    Marusich, M.5    Smeitink, J.6    Capaldi, R.7
  • 24
    • 0025861818 scopus 로고
    • Detection of specific polymerase chain reaction product by utilizing the 5′-3′ exonuclease activity of Thermus aquaticus DNA polymerase
    • Holland, P. M., Abramson, R. D., Watson, R., and Gelfand, D. H. Detection of specific polymerase chain reaction product by utilizing the 5′-3′ exonuclease activity of Thermus aquaticus DNA polymerase. Proc. Natl. Acad. Sci. USA, 88: 7276-7280, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 7276-7280
    • Holland, P.M.1    Abramson, R.D.2    Watson, R.3    Gelfand, D.H.4
  • 25
    • 0015144531 scopus 로고
    • Oxidative phosphorylation and ultrastructural transformation in mitochondria in the intact ascites tumor cell
    • Hackenbrock, C. R., Rehn, T. G., Weinbach, E. C., and Lemasters, J. J. Oxidative phosphorylation and ultrastructural transformation in mitochondria in the intact ascites tumor cell. J. Cell Biol., 51: 123-137, 1971.
    • (1971) J. Cell Biol. , vol.51 , pp. 123-137
    • Hackenbrock, C.R.1    Rehn, T.G.2    Weinbach, E.C.3    Lemasters, J.J.4
  • 26
    • 0017087846 scopus 로고
    • Energy metabolism in respiration deficient and wildtype Chinese hamster fibroblasts in culture
    • Donnely, M., and Scheffler, I. Energy metabolism in respiration deficient and wildtype Chinese hamster fibroblasts in culture. J. Cell. Physiol., 89: 39-52, 1976.
    • (1976) J. Cell. Physiol. , vol.89 , pp. 39-52
    • Donnely, M.1    Scheffler, I.2
  • 27
    • 0021895138 scopus 로고
    • A new generation of Ca2+ indicators with greatly improved fluorescence properties
    • Grynkiewicz, G, Poenie, M., and Tsien, R. Y. A new generation of Ca2+ indicators with greatly improved fluorescence properties. J. Biol. Chem., 260: 3440-3450, 1985.
    • (1985) J. Biol. Chem. , vol.260 , pp. 3440-3450
    • Grynkiewicz, G.1    Poenie, M.2    Tsien, R.Y.3
  • 28
    • 0033776271 scopus 로고    scopus 로고
    • Changes in intramitochondrial and cytosolic pH: Early events that modulate caspase activation during apoptosis
    • Matsuyama, S., Llopis, J., Deveraux, Q. L., Tsien, R. Y., and Reed, J. C. Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis. Nat. Cell Biol., 2: 318-325, 2000.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 318-325
    • Matsuyama, S.1    Llopis, J.2    Deveraux, Q.L.3    Tsien, R.Y.4    Reed, J.C.5
  • 29
    • 0035053264 scopus 로고    scopus 로고
    • Measurement of mitochondrial pH in situ
    • Takahashi, A., Zhang, Y., Centonze, E., and Herman, B. Measurement of mitochondrial pH in situ. Biotechniques, 30: 804-808, 810, 812 passim, 2001.
    • (2001) Biotechniques , vol.30 , pp. 804-808
    • Takahashi, A.1    Zhang, Y.2    Centonze, E.3    Herman, B.4
  • 30
    • 78651031094 scopus 로고
    • The respiratory chain and oxidative phosphorylation
    • Chance, B., and Williams, G. R. The respiratory chain and oxidative phosphorylation. Adv. Enzymol., 17: 65-134, 1956.
    • (1956) Adv. Enzymol. , vol.17 , pp. 65-134
    • Chance, B.1    Williams, G.R.2
  • 31
    • 0016294206 scopus 로고
    • The influence of respiration and ATP hydrolysis on the proton-electrochemical gradient across the inner membrane of rat-liver mitochondria as determined by ion distribution
    • Nicholls, D. G. The influence of respiration and ATP hydrolysis on the proton-electrochemical gradient across the inner membrane of rat-liver mitochondria as determined by ion distribution. Eur. J. Biochem., 50: 305-315, 1974.
    • (1974) Eur. J. Biochem. , vol.50 , pp. 305-315
    • Nicholls, D.G.1
  • 32
    • 0016828104 scopus 로고
    • The measurement of transmembrane electrochemical proton gradients
    • Rottenberg, H. The measurement of transmembrane electrochemical proton gradients. J. Bioenerg., 7: 61-74, 1975.
    • (1975) J. Bioenerg. , vol.7 , pp. 61-74
    • Rottenberg, H.1
  • 33
    • 0023636607 scopus 로고
    • Estimation of intramitochondrial pCa and pH by fura-2 and 2, 7 biscarboxyethyl-5(6)-carboxyfluorescein (BCECF) fluorescence
    • Davis, M. H., Altschuld, R. A., Jung, D. W., and Brierley, G. P. Estimation of intramitochondrial pCa and pH by fura-2 and 2, 7 biscarboxyethyl-5(6)-carboxyfluorescein (BCECF) fluorescence. Biochem. Biophys. Res. Commun., 149: 40-45, 1987.
    • (1987) Biochem. Biophys. Res. Commun. , vol.149 , pp. 40-45
    • Davis, M.H.1    Altschuld, R.A.2    Jung, D.W.3    Brierley, G.P.4
  • 34
    • 0001015125 scopus 로고    scopus 로고
    • Identification of a new type of mammalian peroxiredoxin that forms an intramolecular disulfide as a reaction intermediate
    • Seo, M. S., Kang, S. W., Kim, K., Baines, I. C., Lee, T. H., and Rhee, S. G. Identification of a new type of mammalian peroxiredoxin that forms an intramolecular disulfide as a reaction intermediate. J. Biol. Chem., 275: 20346-54, 2000.
    • (2000) J. Biol. Chem. , vol.275 , pp. 20346-20354
    • Seo, M.S.1    Kang, S.W.2    Kim, K.3    Baines, I.C.4    Lee, T.H.5    Rhee, S.G.6
  • 35
    • 0029874964 scopus 로고    scopus 로고
    • Use of fibroblast and lymphoblast cultures for detection of respiratory chain defects
    • Robinson, B. Use of fibroblast and lymphoblast cultures for detection of respiratory chain defects. Method. Enzymol., 264: 455-464, 1996.
    • (1996) Method. Enzymol. , vol.264 , pp. 455-464
    • Robinson, B.1
  • 36
    • 0035158997 scopus 로고    scopus 로고
    • Dysfunctional mitochondria, not oxygen insufficiency, cause cancer cells to produce inordinate amounts of lactic acid: The impact of this on the treatment of cancer
    • John, A. P. Dysfunctional mitochondria, not oxygen insufficiency, cause cancer cells to produce inordinate amounts of lactic acid: the impact of this on the treatment of cancer. Med. Hypotheses, 57: 429-431, 2001.
    • (2001) Med. Hypotheses , vol.57 , pp. 429-431
    • John, A.P.1
  • 38
    • 0033581893 scopus 로고    scopus 로고
    • Mitochondrial DNA determines the cellular response to cancer therapeutic agents
    • Singh, K. K., Russell, J., Sigala, B., Zhang, Y., Williams, J., and Keshav, K. F. Mitochondrial DNA determines the cellular response to cancer therapeutic agents. Oncogene, 18: 6641-6646, 1999.
    • (1999) Oncogene , vol.18 , pp. 6641-6646
    • Singh, K.K.1    Russell, J.2    Sigala, B.3    Zhang, Y.4    Williams, J.5    Keshav, K.F.6
  • 40
    • 0037056002 scopus 로고    scopus 로고
    • Mitochondrial bound type II hexokinase: A key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention
    • Pedersen, P. L., Mathupala, S., Rempel, A., Geschwind, J. F., and Ko, Y. H. Mitochondrial bound type II hexokinase: a key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention. Biochim. Biophys. Acta, 1555: 14-20, 2002.
    • (2002) Biochim. Biophys. Acta , vol.1555 , pp. 14-20
    • Pedersen, P.L.1    Mathupala, S.2    Rempel, A.3    Geschwind, J.F.4    Ko, Y.H.5
  • 41
    • 0036554644 scopus 로고    scopus 로고
    • Acid production in glycolysis-impaired tumors provides new insights into tumor metabolism
    • Helmlinger, G. S. A., Dellian, M., Forbes, N. S., and Jain, R. K. Acid production in glycolysis-impaired tumors provides new insights into tumor metabolism. Clin. Cancer Res., 8: 1284-1291, 2002.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 1284-1291
    • Helmlinger, G.S.A.1    Dellian, M.2    Forbes, N.S.3    Jain, R.K.4
  • 42
    • 0028047262 scopus 로고
    • Dynamics of mitochondria in living cells: Shape changes, dislocations, fusion, and fission of mitochondria
    • Bereiter-Hahn, J., and Voth, M. Dynamics of mitochondria in living cells: shape changes, dislocations, fusion, and fission of mitochondria. Microsc. Res. Tech., 27: 198-219, 1994.
    • (1994) Microsc. Res. Tech. , vol.27 , pp. 198-219
    • Bereiter-Hahn, J.1    Voth, M.2
  • 43
    • 0030087711 scopus 로고    scopus 로고
    • Double labelling of subcellular structures with organelle-targeted GFP mutants in vivo
    • Rizzuto, R., Brini, M., De Giorgi, F., Rossi, R., Heim, R., Tsien, R. Y. and Pozzan, T. Double labelling of subcellular structures with organelle-targeted GFP mutants in vivo. Curr. Biol., 6: 183-188, 1996.
    • (1996) Curr. Biol. , vol.6 , pp. 183-188
    • Rizzuto, R.1    Brini, M.2    De Giorgi, F.3    Rossi, R.4    Heim, R.5    Tsien, R.Y.6    Pozzan, T.7
  • 44
    • 0034235229 scopus 로고    scopus 로고
    • The internal structure of mitochondria
    • Frey, T. G., and Mannella, C. A. The internal structure of mitochondria. Trends Biochem. Sci., 25: 319-324, 2000.
    • (2000) Trends Biochem. Sci. , vol.25 , pp. 319-324
    • Frey, T.G.1    Mannella, C.A.2
  • 45
    • 0034717114 scopus 로고    scopus 로고
    • Mitochondrial DNA depletion causes morphological changes in the mitochondrial reticulum of cultured human cells
    • Gilkerson, R. W., Margineantu, D. H., Capaldi, R. A., and Selker, J. M. Mitochondrial DNA depletion causes morphological changes in the mitochondrial reticulum of cultured human cells. FEBS Lett., 474: 1-4, 2000.
    • (2000) FEBS Lett. , vol.474 , pp. 1-4
    • Gilkerson, R.W.1    Margineantu, D.H.2    Capaldi, R.A.3    Selker, J.M.4
  • 46
    • 0037494885 scopus 로고    scopus 로고
    • The cristal membrane of mitochondria is the principal site of oxidative phosphorylation
    • Gilkerson, R. W., Selker, J. M., and Capaldi, R. A. The cristal membrane of mitochondria is the principal site of oxidative phosphorylation. FEBS Lett., 546: 355-358, 2003.
    • (2003) FEBS Lett. , vol.546 , pp. 355-358
    • Gilkerson, R.W.1    Selker, J.M.2    Capaldi, R.A.3
  • 47
    • 0013936320 scopus 로고
    • Ultrastructural bases for metabolically linked mechanical activity in mitochondria. I. Reversible ultrastructural changes with change in metabolic steady state in isolated liver mitochondria
    • Hackenbrock, C. R. Ultrastructural bases for metabolically linked mechanical activity in mitochondria. I. Reversible ultrastructural changes with change in metabolic steady state in isolated liver mitochondria. J. Cell Biol., 30: 269-297, 1966.
    • (1966) J. Cell Biol. , vol.30 , pp. 269-297
    • Hackenbrock, C.R.1
  • 48
    • 0014286720 scopus 로고
    • Ultrastructural bases for metabolically linked mechanical activity in mitochondria. II. Electron transport-linked ultrastructural transformations in mitochondria
    • Hackenbrock, C. R. Ultrastructural bases for metabolically linked mechanical activity in mitochondria. II. Electron transport-linked ultrastructural transformations in mitochondria. J. Cell Biol., 37: 345-369, 1968.
    • (1968) J. Cell Biol. , vol.37 , pp. 345-369
    • Hackenbrock, C.R.1
  • 49
    • 0030060683 scopus 로고    scopus 로고
    • Ragged red or ragged blue fibers
    • Reichmann, H., Vogler, L., and Seibel, P. Ragged red or ragged blue fibers. Eur. Neurol., 36: 98-102, 1996.
    • (1996) Eur. Neurol. , vol.36 , pp. 98-102
    • Reichmann, H.1    Vogler, L.2    Seibel, P.3
  • 50
    • 0035909527 scopus 로고    scopus 로고
    • Metabolic cooperation between different oncogenes during cell transformation: Interaction between activated ras and HPV-16 E7
    • Mazurek, S., Zwerschke, W., Jansen-Durr, P., and Eigenbrodt, E. Metabolic cooperation between different oncogenes during cell transformation: interaction between activated ras and HPV-16 E7. Oncogene, 20: 6891-6898, 2001.
    • (2001) Oncogene , vol.20 , pp. 6891-6898
    • Mazurek, S.1    Zwerschke, W.2    Jansen-Durr, P.3    Eigenbrodt, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.