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Volumn 89, Issue 4, 2011, Pages 539-556

Vascular inflammation in central nervous system diseases: Adhesion receptors controlling leukocyte-endothelial interactions

Author keywords

Alzheimer's disease; Epilepsy; Integrins; Multiple sclerosis; Selectins; Stroke

Indexed keywords

ALPHA4BETA7 INTEGRIN; ALPHALBETA2 INTEGRIN; ALPHAMBETA2 INTEGRIN; CELL ADHESION MOLECULE; CELL RECEPTOR; CHEMOATTRACTANT; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTEGRIN; L SELECTIN; PADGEM PROTEIN; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 4;

EID: 79953701030     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0710432     Document Type: Review
Times cited : (147)

References (285)
  • 1
    • 0026342111 scopus 로고
    • Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity
    • Butcher, E. C. (1991) Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. Cell 67, 1033-1036.
    • (1991) Cell , vol.67 , pp. 1033-1036
    • Butcher, E.C.1
  • 2
    • 0027982876 scopus 로고
    • Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
    • Springer, T. A. (1994) Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76, 301-314.
    • (1994) Cell , vol.76 , pp. 301-314
    • Springer, T.A.1
  • 3
    • 30044447736 scopus 로고    scopus 로고
    • Immune cell migration in inflammation: Present and future therapeutic targets
    • Luster, A. D., Alon, R., von Andrian, U. H. (2005) Immune cell migration in inflammation: present and future therapeutic targets. Nat. Immunol. 6, 1182-1190.
    • (2005) Nat. Immunol. , vol.6 , pp. 1182-1190
    • Luster, A.D.1    Alon, R.2    von Andrian, U.H.3
  • 4
    • 34548230927 scopus 로고    scopus 로고
    • Getting to the site of inflammation: The leukocyte adhesion cascade updated
    • Ley, K., Laudanna, C., Cybulsky, M. I., Nourshargh, S. (2007) Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat. Rev. Immunol. 7, 678-689.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 678-689
    • Ley, K.1    Laudanna, C.2    Cybulsky, M.I.3    Nourshargh, S.4
  • 5
  • 7
    • 2342471420 scopus 로고    scopus 로고
    • The blood-brain barrier: An overview: Structure, regulation, and clinical implications
    • Ballabh, P., Braun, A., Nedergaard, M. (2004) The blood-brain barrier: an overview: structure, regulation, and clinical implications. Neurobiol. Dis. 16, 1-13.
    • (2004) Neurobiol. Dis. , vol.16 , pp. 1-13
    • Ballabh, P.1    Braun, A.2    Nedergaard, M.3
  • 8
    • 29244463365 scopus 로고    scopus 로고
    • Astrocyte-endothelial interactions at the blood-brain barrier
    • Abbott, N. J., Ronnback, L., Hansson, E. (2006) Astrocyte-endothelial interactions at the blood-brain barrier. Nat. Rev. Neurosci. 7, 41-53.
    • (2006) Nat. Rev. Neurosci. , vol.7 , pp. 41-53
    • Abbott, N.J.1    Ronnback, L.2    Hansson, E.3
  • 9
    • 2442519018 scopus 로고    scopus 로고
    • Selectins in T-cell recruitment to non-lymphoid tissues and sites of inflammation
    • Ley, K., Kansas, G. S. (2004) Selectins in T-cell recruitment to non-lymphoid tissues and sites of inflammation. Nat. Rev. Immunol. 4, 325-335.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 325-335
    • Ley, K.1    Kansas, G.S.2
  • 11
    • 1942542931 scopus 로고    scopus 로고
    • Ligands for L-selectin: Homing, inflammation, and beyond
    • Rosen, S. D. (2004) Ligands for L-selectin: homing, inflammation, and beyond. Annu. Rev. Immunol. 22, 129-156.
    • (2004) Annu. Rev. Immunol. , vol.22 , pp. 129-156
    • Rosen, S.D.1
  • 12
    • 0035898462 scopus 로고    scopus 로고
    • Importance of primary capture and L-selectin-dependent secondary capture in leukocyte accumulation in inflammation and atherosclerosis in vivo
    • Eriksson, E. E., Xie, X., Werr, J., Thoren, P., Lindbom, L. (2001) Importance of primary capture and L-selectin-dependent secondary capture in leukocyte accumulation in inflammation and atherosclerosis in vivo. J. Exp. Med. 194, 205-218.
    • (2001) J. Exp. Med. , vol.194 , pp. 205-218
    • Eriksson, E.E.1    Xie, X.2    Werr, J.3    Thoren, P.4    Lindbom, L.5
  • 13
    • 0038190854 scopus 로고    scopus 로고
    • P-selectin glycoprotein ligand-1 mediates L-selectindependent leukocyte rolling in venules
    • Sperandio, M., Smith, M. L., Forlow, S. B., Olson, T. S., Xia, L., McEver, R. P., Ley, K. (2003) P-selectin glycoprotein ligand-1 mediates L-selectindependent leukocyte rolling in venules. J. Exp. Med. 197, 1355-1363.
    • (2003) J. Exp. Med. , vol.197 , pp. 1355-1363
    • Sperandio, M.1    Smith, M.L.2    Forlow, S.B.3    Olson, T.S.4    Xia, L.5    McEver, R.P.6    Ley, K.7
  • 17
    • 0028011917 scopus 로고
    • Characterization of E-selectin expression in vivo with use of a radiolabeled monoclonal antibody
    • Keelan, E. T., Licence, S. T., Peters, A. M., Binns, R. M., Haskard, D. O. (1994) Characterization of E-selectin expression in vivo with use of a radiolabeled monoclonal antibody. Am. J. Physiol. 266, H278-H290.
    • (1994) Am. J. Physiol. , vol.266
    • Keelan, E.T.1    Licence, S.T.2    Peters, A.M.3    Binns, R.M.4    Haskard, D.O.5
  • 18
    • 0029858031 scopus 로고    scopus 로고
    • Selectins and their ligands: Current concepts and controversies
    • Kansas, G. S. (1996) Selectins and their ligands: current concepts and controversies. Blood 88, 3259-3287.
    • (1996) Blood , vol.88 , pp. 3259-3287
    • Kansas, G.S.1
  • 19
    • 0038603921 scopus 로고    scopus 로고
    • The role of selectins in inflammation and disease
    • Ley, K. (2003) The role of selectins in inflammation and disease. Trends Mol. Med. 9, 263-268.
    • (2003) Trends Mol. Med. , vol.9 , pp. 263-268
    • Ley, K.1
  • 20
    • 12344275686 scopus 로고    scopus 로고
    • PSGL-1 as a novel therapeutic target
    • Constantin, G. (2004) PSGL-1 as a novel therapeutic target. Drug News Perspect. 17, 579-586.
    • (2004) Drug News Perspect. , vol.17 , pp. 579-586
    • Constantin, G.1
  • 22
    • 34247108244 scopus 로고    scopus 로고
    • Complete identification of E-selectin ligands on neutrophils reveals distinct functions of PSGL-1, ESL-1, and CD44
    • Hidalgo, A., Peired, A. J., Wild, M. K., Vestweber, D., Frenette, P. S. (2007) Complete identification of E-selectin ligands on neutrophils reveals distinct functions of PSGL-1, ESL-1, and CD44. Immunity 26, 477-489.
    • (2007) Immunity , vol.26 , pp. 477-489
    • Hidalgo, A.1    Peired, A.J.2    Wild, M.K.3    Vestweber, D.4    Frenette, P.S.5
  • 23
    • 0034235394 scopus 로고    scopus 로고
    • The LFA-1 integrin supports rolling adhesions on ICAM-1 under physiological shear flow in a permissive cellular environment
    • Sigal, A., Bleijs, D. A., Grabovsky, V., van Vliet, S. J., Dwir, O., Figdor, C. G., van Kooyk, Y., Alon, R. (2000) The LFA-1 integrin supports rolling adhesions on ICAM-1 under physiological shear flow in a permissive cellular environment. J. Immunol. 165, 442-452.
    • (2000) J. Immunol. , vol.165 , pp. 442-452
    • Sigal, A.1    Bleijs, D.A.2    Grabovsky, V.3    van Vliet, S.J.4    Dwir, O.5    Figdor, C.G.6    van Kooyk, Y.7    Alon, R.8
  • 24
    • 0034744558 scopus 로고    scopus 로고
    • Functional α4-integrin: A newly identified pathway of neutrophil recruitment in critically ill septic patients
    • Ibbotson, G. C., Doig, C., Kaur, J., Gill, V., Ostrovsky, L., Fairhead, T., Kubes, P. (2001) Functional α4-integrin: a newly identified pathway of neutrophil recruitment in critically ill septic patients. Nat. Med. 7, 465-470.
    • (2001) Nat. Med. , vol.7 , pp. 465-470
    • Ibbotson, G.C.1    Doig, C.2    Kaur, J.3    Gill, V.4    Ostrovsky, L.5    Fairhead, T.6    Kubes, P.7
  • 25
    • 50049088852 scopus 로고    scopus 로고
    • The multistep model of leukocyte recruitment: A personal perspective from 15 year later
    • In, (A. E. Haman, ed.), Germany, Wiley-VCH
    • Butcher, E. C. (2005) The multistep model of leukocyte recruitment: a personal perspective from 15 year later. In Leukocyte Trafficking (A. E. Haman, ed.), Germany, Wiley-VCH, 3-13.
    • (2005) Leukocyte Trafficking , pp. 3-13
    • Butcher, E.C.1
  • 26
    • 27544508178 scopus 로고    scopus 로고
    • A sulfated address for lymphocyte homing
    • McEver, R. P. (2005) A sulfated address for lymphocyte homing. Nat. Immunol. 6, 1067-1069.
    • (2005) Nat. Immunol. , vol.6 , pp. 1067-1069
    • McEver, R.P.1
  • 27
    • 0037083641 scopus 로고    scopus 로고
    • Molecular mechanisms involved in lymphocyte recruitment in inflamed brain microvessels: Critical roles for P-selectin glycoprotein ligand-1 and heterotrimeric G(i)-linked receptors
    • Piccio, L., Rossi, B., Scarpini, E., Laudanna, C., Giagulli, C., Issekutz, A. C., Vestweber, D., Butcher, E. C., Constantin, G. (2002) Molecular mechanisms involved in lymphocyte recruitment in inflamed brain microvessels: critical roles for P-selectin glycoprotein ligand-1 and heterotrimeric G(i)-linked receptors. J. Immunol. 168, 1940-1949.
    • (2002) J. Immunol. , vol.168 , pp. 1940-1949
    • Piccio, L.1    Rossi, B.2    Scarpini, E.3    Laudanna, C.4    Giagulli, C.5    Issekutz, A.C.6    Vestweber, D.7    Butcher, E.C.8    Constantin, G.9
  • 29
    • 0034116088 scopus 로고    scopus 로고
    • The CD44-initiated pathway of T-cell extravasation uses VLA-4 but not LFA-1 for firm adhesion
    • Siegelman, M. H., Stanescu, D., Estess, P. (2000) The CD44-initiated pathway of T-cell extravasation uses VLA-4 but not LFA-1 for firm adhesion. J. Clin. Invest. 105, 683-691.
    • (2000) J. Clin. Invest. , vol.105 , pp. 683-691
    • Siegelman, M.H.1    Stanescu, D.2    Estess, P.3
  • 30
    • 1842633889 scopus 로고    scopus 로고
    • Bimolecular complex between rolling and firm adhesion receptors required for cell arrest; CD44 association with VLA-4 in T cell extravasation
    • Nandi, A., Estess, P., Siegelman, M. (2004) Bimolecular complex between rolling and firm adhesion receptors required for cell arrest; CD44 association with VLA-4 in T cell extravasation. Immunity 20, 455-465.
    • (2004) Immunity , vol.20 , pp. 455-465
    • Nandi, A.1    Estess, P.2    Siegelman, M.3
  • 32
    • 34447314985 scopus 로고    scopus 로고
    • Integrin modulation and signaling in leukocyte adhesion and migration
    • Rose, D. M., Alon, R., Ginsberg, M. H. (2007) Integrin modulation and signaling in leukocyte adhesion and migration. Immunol. Rev. 218, 126-134.
    • (2007) Immunol. Rev. , vol.218 , pp. 126-134
    • Rose, D.M.1    Alon, R.2    Ginsberg, M.H.3
  • 33
    • 67349213676 scopus 로고    scopus 로고
    • A molecular trio in relapse and remission in multiple sclerosis
    • Steinman, L. (2009) A molecular trio in relapse and remission in multiple sclerosis. Nat. Rev. Immunol. 9, 440-447.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 440-447
    • Steinman, L.1
  • 34
    • 0032514916 scopus 로고    scopus 로고
    • Evidence of ζ protein kinase C involvement in polymorphonuclear neutrophil integrin-dependent adhesion and chemotaxis
    • Laudanna, C., Mochly-Rosen, D., Liron, T., Constantin, G., Butcher, E. C. (1998) Evidence of ζ protein kinase C involvement in polymorphonuclear neutrophil integrin-dependent adhesion and chemotaxis. J. Biol. Chem. 273, 30306-30315.
    • (1998) J. Biol. Chem. , vol.273 , pp. 30306-30315
    • Laudanna, C.1    Mochly-Rosen, D.2    Liron, T.3    Constantin, G.4    Butcher, E.C.5
  • 36
    • 0023819138 scopus 로고
    • Neutrophil adherence to human endothelium in vitro occurs by CDw18 (Mo1, MAC-1/LFA-1/GP 150,95) glycoprotein-dependent and-independent mechanisms
    • Zimmerman, G. A., McIntyre, T. M. (1988) Neutrophil adherence to human endothelium in vitro occurs by CDw18 (Mo1, MAC-1/LFA-1/GP 150,95) glycoprotein-dependent and-independent mechanisms. J. Clin. Invest. 81, 531-537.
    • (1988) J. Clin. Invest. , vol.81 , pp. 531-537
    • Zimmerman, G.A.1    McIntyre, T.M.2
  • 37
    • 0142092620 scopus 로고    scopus 로고
    • Leukotriene B4 and BLT1 control cytotoxic effector T cell recruitment to inflamed tissues
    • Goodarzi, K., Goodarzi, M., Tager, A. M., Luster, A. D., von Andrian, U. H. (2003) Leukotriene B4 and BLT1 control cytotoxic effector T cell recruitment to inflamed tissues. Nat. Immunol. 4, 965-973.
    • (2003) Nat. Immunol. , vol.4 , pp. 965-973
    • Goodarzi, K.1    Goodarzi, M.2    Tager, A.M.3    Luster, A.D.4    von Andrian, U.H.5
  • 40
    • 0242441474 scopus 로고    scopus 로고
    • Human cellular inflammation in the pathology of acute cerebral ischemia
    • Price, C. J., Warburton, E. A., Menon, D. K. (2003) Human cellular inflammation in the pathology of acute cerebral ischemia. J. Neurol. Neurosurg. Psychiatry 74, 1476-1484.
    • (2003) J. Neurol. Neurosurg. Psychiatry , vol.74 , pp. 1476-1484
    • Price, C.J.1    Warburton, E.A.2    Menon, D.K.3
  • 41
    • 84984763363 scopus 로고    scopus 로고
    • Mechanisms, challenges and opportunities in stroke
    • Lo, E. H., Dalkara, T., Moskowitz, M. A. (2003) Mechanisms, challenges and opportunities in stroke. Nat. Rev. Neurosci. 4, 399-415.
    • (2003) Nat. Rev. Neurosci. , vol.4 , pp. 399-415
    • Lo, E.H.1    Dalkara, T.2    Moskowitz, M.A.3
  • 42
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischemic stroke: An integrated view
    • Dirnagl, U., Iadecola, C., Moskowitz, M. A. (1999) Pathobiology of ischemic stroke: an integrated view. Trends Neurosci. 22, 391-397.
    • (1999) Trends Neurosci. , vol.22 , pp. 391-397
    • Dirnagl, U.1    Iadecola, C.2    Moskowitz, M.A.3
  • 43
    • 0348048849 scopus 로고    scopus 로고
    • The ischemic penumbra: Identification, evolution and treatment concepts
    • Fisher, M. (2004) The ischemic penumbra: identification, evolution and treatment concepts. Cerebrovasc. Dis. 17 (Suppl. 1), 1-6.
    • (2004) Cerebrovasc. Dis. , vol.17 , Issue.SUPPL. 1 , pp. 1-6
    • Fisher, M.1
  • 45
    • 0032473602 scopus 로고    scopus 로고
    • The expression of P-and E-selectins in three models of middle cerebral artery occlusion
    • Zhang, R., Chopp, M., Zhang, Z., Jiang, N., Powers, C. (1998) The expression of P-and E-selectins in three models of middle cerebral artery occlusion. Brain Res. 785, 207-214.
    • (1998) Brain Res. , vol.785 , pp. 207-214
    • Zhang, R.1    Chopp, M.2    Zhang, Z.3    Jiang, N.4    Powers, C.5
  • 47
    • 0342872047 scopus 로고    scopus 로고
    • Exacerbation of cerebral injury in mice that express the P-selectin gene: Identification of P-selectin blockade as a new target for the treatment of stroke
    • Connolly Jr., E. S., Winfree, C. J., Prestigiacomo, C. J., Kim, S. C., Choudhri, T. F., Hoh, B. L., Naka, Y., Solomon, R. A., Pinsky, D. J. (1997) Exacerbation of cerebral injury in mice that express the P-selectin gene: identification of P-selectin blockade as a new target for the treatment of stroke. Circ. Res. 81, 304-310.
    • (1997) Circ. Res. , vol.81 , pp. 304-310
    • Connolly Jr., E.S.1    Winfree, C.J.2    Prestigiacomo, C.J.3    Kim, S.C.4    Choudhri, T.F.5    Hoh, B.L.6    Naka, Y.7    Solomon, R.A.8    Pinsky, D.J.9
  • 48
    • 0030665650 scopus 로고    scopus 로고
    • Soluble adhesion molecules reflect endothelial cell activation in ischemic stroke and in carotid atherosclerosis
    • Frijns, C. J., Kappelle, L. J., van Gijn, J., Nieuwenhuis, H. K., Sixma, J. J., Fijnheer, R. (1997) Soluble adhesion molecules reflect endothelial cell activation in ischemic stroke and in carotid atherosclerosis. Stroke 28, 2214-2218.
    • (1997) Stroke , vol.28 , pp. 2214-2218
    • Frijns, C.J.1    Kappelle, L.J.2    van Gijn, J.3    Nieuwenhuis, H.K.4    Sixma, J.J.5    Fijnheer, R.6
  • 49
    • 0029100108 scopus 로고
    • Circulating selectin-and immunoglobulin-type adhesion molecules in acute ischemic stroke
    • Fassbender, K., Mossner, R., Motsch, L., Kischka, U., Grau, A., Hennerici, M. (1995) Circulating selectin-and immunoglobulin-type adhesion molecules in acute ischemic stroke. Stroke 26, 1361-1364.
    • (1995) Stroke , vol.26 , pp. 1361-1364
    • Fassbender, K.1    Mossner, R.2    Motsch, L.3    Kischka, U.4    Grau, A.5    Hennerici, M.6
  • 50
    • 0031036884 scopus 로고    scopus 로고
    • Serum levels of intercellular adhesion molecule-1 and E-selectin in patients with acute ischemic stroke
    • Shyu, K. G., Chang, H., Lin, C. C. (1997) Serum levels of intercellular adhesion molecule-1 and E-selectin in patients with acute ischemic stroke. J. Neurol. 244, 90-93.
    • (1997) J. Neurol. , vol.244 , pp. 90-93
    • Shyu, K.G.1    Chang, H.2    Lin, C.C.3
  • 51
    • 0031681362 scopus 로고    scopus 로고
    • A longitudinal prospective study of soluble adhesion molecules in acute stroke
    • Bitsch, A., Klene, W., Murtada, L., Prange, H., Rieckmann, P. (1998) A longitudinal prospective study of soluble adhesion molecules in acute stroke. Stroke 29, 2129-2135.
    • (1998) Stroke , vol.29 , pp. 2129-2135
    • Bitsch, A.1    Klene, W.2    Murtada, L.3    Prange, H.4    Rieckmann, P.5
  • 52
    • 67649523011 scopus 로고    scopus 로고
    • Elevated levels of soluble P-selectin in mice alter blood-brain barrier function, exacerbate stroke, and promote atherosclerosis
    • Kisucka, J., Chauhan, A. K., Zhao, B. Q., Patten, I. S., Yesilaltay, A., Krieger, M., Wagner, D. D. (2009) Elevated levels of soluble P-selectin in mice alter blood-brain barrier function, exacerbate stroke, and promote atherosclerosis. Blood 113, 6015-6022.
    • (2009) Blood , vol.113 , pp. 6015-6022
    • Kisucka, J.1    Chauhan, A.K.2    Zhao, B.Q.3    Patten, I.S.4    Yesilaltay, A.5    Krieger, M.6    Wagner, D.D.7
  • 53
    • 33644833413 scopus 로고    scopus 로고
    • Raised plasma soluble P-selectin in peripheral arterial occlusive disease enhances leukocyte adhesion
    • Woollard, K. J., Kling, D., Kulkarni, S., Dart, A. M., Jackson, S., Chin-Dusting, J. (2006) Raised plasma soluble P-selectin in peripheral arterial occlusive disease enhances leukocyte adhesion. Circ. Res. 98, 149-156.
    • (2006) Circ. Res. , vol.98 , pp. 149-156
    • Woollard, K.J.1    Kling, D.2    Kulkarni, S.3    Dart, A.M.4    Jackson, S.5    Chin-Dusting, J.6
  • 54
    • 0032569874 scopus 로고    scopus 로고
    • P-selectin antibody reduces hemorrhage and infarct volume resulting from MCA occlusion in the rat
    • Goussev, A. V., Zhang, Z., Anderson, D. C., Chopp, M. (1998) P-selectin antibody reduces hemorrhage and infarct volume resulting from MCA occlusion in the rat. J. Neurol. Sci. 161, 16-22.
    • (1998) J. Neurol. Sci. , vol.161 , pp. 16-22
    • Goussev, A.V.1    Zhang, Z.2    Anderson, D.C.3    Chopp, M.4
  • 55
    • 77649097668 scopus 로고    scopus 로고
    • Reduced blood brain barrier breakdown in P-selectin deficient mice following transient ischemic stroke: A future therapeutic target for treatment of stroke
    • Jin, A. Y., Tuor, U. I., Rushforth, D., Kaur, J., Muller, R. N., Petterson, J. L., Boutry, S., Barber, P. A. (2010) Reduced blood brain barrier breakdown in P-selectin deficient mice following transient ischemic stroke: a future therapeutic target for treatment of stroke. BMC Neurosci. 11, 12.
    • (2010) BMC Neurosci. , vol.11 , pp. 12
    • Jin, A.Y.1    Tuor, U.I.2    Rushforth, D.3    Kaur, J.4    Muller, R.N.5    Petterson, J.L.6    Boutry, S.7    Barber, P.A.8
  • 60
    • 0036712364 scopus 로고    scopus 로고
    • Induction of mucosal tolerance to E-selectin prevents ischemic and hemorrhagic stroke in spontaneously hypertensive genetically stroke-prone rats
    • Takeda, H., Spatz, M., Ruetzler, C., McCarron, R., Becker, K., Hallenbeck, J. (2002) Induction of mucosal tolerance to E-selectin prevents ischemic and hemorrhagic stroke in spontaneously hypertensive genetically stroke-prone rats. Stroke 33, 2156-2163.
    • (2002) Stroke , vol.33 , pp. 2156-2163
    • Takeda, H.1    Spatz, M.2    Ruetzler, C.3    McCarron, R.4    Becker, K.5    Hallenbeck, J.6
  • 61
    • 56349145206 scopus 로고    scopus 로고
    • Mucosal tolerance to E-selectin provides protection against cerebral ischemia-reperfusion injury in rats
    • Yun, W., Qing-Cheng, L., Lei, Y., Jia-Yin, M. (2008) Mucosal tolerance to E-selectin provides protection against cerebral ischemia-reperfusion injury in rats. J. Neuroimmunol. 205, 73-79.
    • (2008) J. Neuroimmunol. , vol.205 , pp. 73-79
    • Yun, W.1    Qing-Cheng, L.2    Lei, Y.3    Jia-Yin, M.4
  • 62
    • 0035143607 scopus 로고    scopus 로고
    • Lselectin inhibition does not reduce injury in a rabbit model of transient focal cerebral ischemia
    • Yenari, M. A., Sun, G. H., Kunis, D. M., Onley, D., Vexler, V. (2001) Lselectin inhibition does not reduce injury in a rabbit model of transient focal cerebral ischemia. Neurol. Res. 23, 72-78.
    • (2001) Neurol. Res. , vol.23 , pp. 72-78
    • Yenari, M.A.1    Sun, G.H.2    Kunis, D.M.3    Onley, D.4    Vexler, V.5
  • 63
    • 56149099017 scopus 로고    scopus 로고
    • Anti-selectin therapy for the treatment of inflammatory diseases
    • Rossi, B., Constantin, G. (2008) Anti-selectin therapy for the treatment of inflammatory diseases. Inflamm. Allergy Drug Targets 7, 85-93.
    • (2008) Inflamm. Allergy Drug Targets , vol.7 , pp. 85-93
    • Rossi, B.1    Constantin, G.2
  • 64
    • 0028138184 scopus 로고
    • Upregulation of intercellular adhesion molecule 1 (ICAM-1) on brain microvascular endothelial cells in rat ischemic cortex
    • Wang, X., Siren, A. L., Liu, Y., Yue, T. L., Barone, F. C., Feuerstein, G. Z. (1994) Upregulation of intercellular adhesion molecule 1 (ICAM-1) on brain microvascular endothelial cells in rat ischemic cortex. Brain Res. Mol. Brain Res. 26, 61-68.
    • (1994) Brain Res. Mol. Brain Res. , vol.26 , pp. 61-68
    • Wang, X.1    Siren, A.L.2    Liu, Y.3    Yue, T.L.4    Barone, F.C.5    Feuerstein, G.Z.6
  • 66
    • 0027200051 scopus 로고
    • Monoclonal antibody to the ICAM-1 adhesion site reduces neurological damage in a rabbit cerebral embolism stroke model
    • Bowes, M. P., Zivin, J. A., Rothlein, R. (1993) Monoclonal antibody to the ICAM-1 adhesion site reduces neurological damage in a rabbit cerebral embolism stroke model. Exp. Neurol. 119, 215-219.
    • (1993) Exp. Neurol. , vol.119 , pp. 215-219
    • Bowes, M.P.1    Zivin, J.A.2    Rothlein, R.3
  • 67
    • 0029972079 scopus 로고    scopus 로고
    • Antibodies against adhesion molecules reduce apoptosis after transient middle cerebral artery occlusion in rat brain
    • Chopp, M., Li, Y., Jiang, N., Zhang, R. L., Prostak, J. (1996) Antibodies against adhesion molecules reduce apoptosis after transient middle cerebral artery occlusion in rat brain. J. Cereb. Blood Flow Metab. 16, 578-584.
    • (1996) J. Cereb. Blood Flow Metab. , vol.16 , pp. 578-584
    • Chopp, M.1    Li, Y.2    Jiang, N.3    Zhang, R.L.4    Prostak, J.5
  • 68
    • 0026003119 scopus 로고
    • Reduction of central nervous system ischemic injury by monoclonal antibody to intercellular adhesion molecule
    • Clark, W. M., Madden, K. P., Rothlein, R., Zivin, J. A. (1991) Reduction of central nervous system ischemic injury by monoclonal antibody to intercellular adhesion molecule. J. Neurosurg. 75, 623-627.
    • (1991) J. Neurosurg. , vol.75 , pp. 623-627
    • Clark, W.M.1    Madden, K.P.2    Rothlein, R.3    Zivin, J.A.4
  • 69
    • 0036820911 scopus 로고    scopus 로고
    • Effects of antiintercellular adhesion molecule-1 antibody on reperfusion injury induced by late reperfusion in the rat middle cerebral artery occlusion model
    • Kanemoto, Y., Nakase, H., Akita, N., Sakaki, T. (2002) Effects of antiintercellular adhesion molecule-1 antibody on reperfusion injury induced by late reperfusion in the rat middle cerebral artery occlusion model. Neurosurgery 51, 1034-1041.
    • (2002) Neurosurgery , vol.51 , pp. 1034-1041
    • Kanemoto, Y.1    Nakase, H.2    Akita, N.3    Sakaki, T.4
  • 70
    • 0347356514 scopus 로고    scopus 로고
    • Inhibition of intercellular adhesion molecule-1 protein expression by antisense oligonucleotides is neuroprotective after transient middle cerebral artery occlusion in rat
    • Vemuganti, R., Dempsey, R. J., Bowen, K. K. (2004) Inhibition of intercellular adhesion molecule-1 protein expression by antisense oligonucleotides is neuroprotective after transient middle cerebral artery occlusion in rat. Stroke 35, 179-184.
    • (2004) Stroke , vol.35 , pp. 179-184
    • Vemuganti, R.1    Dempsey, R.J.2    Bowen, K.K.3
  • 71
    • 0029886071 scopus 로고    scopus 로고
    • Intercellular adhesion molecule-1-deficient mice are less susceptible to cerebral ischemia-reperfusion injury
    • Soriano, S. G., Lipton, S. A., Wang, Y. F., Xiao, M., Springer, T. A., Gutierrez-Ramos, J. C., Hickey, P. R. (1996) Intercellular adhesion molecule-1-deficient mice are less susceptible to cerebral ischemia-reperfusion injury. Ann. Neurol. 39, 618-624.
    • (1996) Ann. Neurol. , vol.39 , pp. 618-624
    • Soriano, S.G.1    Lipton, S.A.2    Wang, Y.F.3    Xiao, M.4    Springer, T.A.5    Gutierrez-Ramos, J.C.6    Hickey, P.R.7
  • 73
    • 0031742806 scopus 로고    scopus 로고
    • Deficiency of intercellular adhesion molecule1 attenuates microcirculatory disturbance and infarction size in focal cerebral ischemia
    • Kitagawa, K., Matsumoto, M., Mabuchi, T., Yagita, Y., Ohtsuki, T., Hori, M., Yanagihara, T. (1998) Deficiency of intercellular adhesion molecule1 attenuates microcirculatory disturbance and infarction size in focal cerebral ischemia. J. Cereb. Blood Flow Metab. 18, 1336-1345.
    • (1998) J. Cereb. Blood Flow Metab. , vol.18 , pp. 1336-1345
    • Kitagawa, K.1    Matsumoto, M.2    Mabuchi, T.3    Yagita, Y.4    Ohtsuki, T.5    Hori, M.6    Yanagihara, T.7
  • 75
    • 0028351503 scopus 로고
    • Anti-CD11b monoclonal antibody reduces ischemic cell damage after transient focal cerebral ischemia in rat
    • Chen, H., Chopp, M., Zhang, R. L., Bodzin, G., Chen, Q., Rusche, J. R., Todd III, R. F. (1994) Anti-CD11b monoclonal antibody reduces ischemic cell damage after transient focal cerebral ischemia in rat. Ann. Neurol. 35, 458-463.
    • (1994) Ann. Neurol. , vol.35 , pp. 458-463
    • Chen, H.1    Chopp, M.2    Zhang, R.L.3    Bodzin, G.4    Chen, Q.5    Rusche, J.R.6    Todd III, R.F.7
  • 76
    • 0028911203 scopus 로고
    • Monoclonal antibodies preventing leukocyte activation reduce experimental neurologic injury and enhance efficacy of thrombolytic therapy
    • Bowes, M. P., Rothlein, R., Fagan, S. C., Zivin, J. A. (1995) Monoclonal antibodies preventing leukocyte activation reduce experimental neurologic injury and enhance efficacy of thrombolytic therapy. Neurology 45, 815-819.
    • (1995) Neurology , vol.45 , pp. 815-819
    • Bowes, M.P.1    Rothlein, R.2    Fagan, S.C.3    Zivin, J.A.4
  • 77
    • 0025768180 scopus 로고
    • Reduction of central nervous system ischemic injury in rabbits using leukocyte adhesion antibody treatment
    • Clark, W. M., Madden, K. P., Rothlein, R., Zivin, J. A. (1991) Reduction of central nervous system ischemic injury in rabbits using leukocyte adhesion antibody treatment. Stroke 22, 877-883.
    • (1991) Stroke , vol.22 , pp. 877-883
    • Clark, W.M.1    Madden, K.P.2    Rothlein, R.3    Zivin, J.A.4
  • 78
    • 0345251951 scopus 로고    scopus 로고
    • Increased therapeutic efficacy with rt-PA and anti-CD18 antibody treatment of stroke in the rat
    • Zhang, R. L., Zhang, Z. G., Chopp, M. (1999) Increased therapeutic efficacy with rt-PA and anti-CD18 antibody treatment of stroke in the rat. Neurology 52, 273-279.
    • (1999) Neurology , vol.52 , pp. 273-279
    • Zhang, R.L.1    Zhang, Z.G.2    Chopp, M.3
  • 79
    • 0029990198 scopus 로고    scopus 로고
    • IB4, a monoclonal antibody against the CD18 leukocyte adhesion protein, reduces intracranial pressure following thromboembolic stroke in the rabbit
    • Bednar, M. M., Wright, S. D., Raymond-Russell, S. J., Kohut, J. J., Gross, C. E. (1996) IB4, a monoclonal antibody against the CD18 leukocyte adhesion protein, reduces intracranial pressure following thromboembolic stroke in the rabbit. Neurol. Res. 18, 171-175.
    • (1996) Neurol. Res. , vol.18 , pp. 171-175
    • Bednar, M.M.1    Wright, S.D.2    Raymond-Russell, S.J.3    Kohut, J.J.4    Gross, C.E.5
  • 80
    • 0032192489 scopus 로고    scopus 로고
    • Hu23F2G, an antibody recognizing the leukocyte CD11/CD18 integrin, reduces injury in a rabbit model of transient focal cerebral ischemia
    • Yenari, M. A., Kunis, D., Sun, G. H., Onley, D., Watson, L., Turner, S., Whitaker, S., Steinberg, G. K. (1998) Hu23F2G, an antibody recognizing the leukocyte CD11/CD18 integrin, reduces injury in a rabbit model of transient focal cerebral ischemia. Exp. Neurol. 153, 223-233.
    • (1998) Exp. Neurol. , vol.153 , pp. 223-233
    • Yenari, M.A.1    Kunis, D.2    Sun, G.H.3    Onley, D.4    Watson, L.5    Turner, S.6    Whitaker, S.7    Steinberg, G.K.8
  • 81
    • 0010214650 scopus 로고
    • Postischemic administration of an anti-Mac-1 antibody reduces ischemic cell damage after transient middle cerebral artery occlusion in rats
    • Chopp, M., Zhang, R. L., Chen, H., Li, Y., Jiang, N., Rusche, J. R. (1994) Postischemic administration of an anti-Mac-1 antibody reduces ischemic cell damage after transient middle cerebral artery occlusion in rats. Stroke 25, 869-875.
    • (1994) Stroke , vol.25 , pp. 869-875
    • Chopp, M.1    Zhang, R.L.2    Chen, H.3    Li, Y.4    Jiang, N.5    Rusche, J.R.6
  • 82
    • 0030069823 scopus 로고    scopus 로고
    • Effects of CD11b/18 monoclonal antibody on rats with permanent middle cerebral artery occlusion
    • Garcia, J. H., Liu, K. F., Bree, M. P. (1996) Effects of CD11b/18 monoclonal antibody on rats with permanent middle cerebral artery occlusion. Am. J. Pathol. 148, 241-248.
    • (1996) Am. J. Pathol. , vol.148 , pp. 241-248
    • Garcia, J.H.1    Liu, K.F.2    Bree, M.P.3
  • 83
    • 0032959532 scopus 로고    scopus 로고
    • CD18-mediated neutrophil recruitment contributes to the pathogenesis of reperfused but not nonreperfused stroke
    • Prestigiacomo, C. J., Kim, S. C., Connolly Jr., E. S., Liao, H., Yan, S. F., Pinsky, D. J. (1999) CD18-mediated neutrophil recruitment contributes to the pathogenesis of reperfused but not nonreperfused stroke. Stroke 30, 1110-1117.
    • (1999) Stroke , vol.30 , pp. 1110-1117
    • Prestigiacomo, C.J.1    Kim, S.C.2    Connolly Jr., E.S.3    Liao, H.4    Yan, S.F.5    Pinsky, D.J.6
  • 84
    • 0032930869 scopus 로고    scopus 로고
    • Mice deficient in Mac-1 (CD11b/ CD18) are less susceptible to cerebral ischemia/reperfusion injury
    • Soriano, S. G., Coxon, A., Wang, Y. F., Frosch, M. P., Lipton, S. A., Hickey, P. R., Mayadas, T. N. (1999) Mice deficient in Mac-1 (CD11b/ CD18) are less susceptible to cerebral ischemia/reperfusion injury. Stroke 30, 134-139.
    • (1999) Stroke , vol.30 , pp. 134-139
    • Soriano, S.G.1    Coxon, A.2    Wang, Y.F.3    Frosch, M.P.4    Lipton, S.A.5    Hickey, P.R.6    Mayadas, T.N.7
  • 86
    • 0034746690 scopus 로고    scopus 로고
    • Antibody to the α4 integrin decreases infarct size in transient focal cerebral ischemia in rats
    • Becker, K., Kindrick, D., Relton, J., Harlan, J., Winn, R. (2001) Antibody to the α4 integrin decreases infarct size in transient focal cerebral ischemia in rats. Stroke 32, 206-211.
    • (2001) Stroke , vol.32 , pp. 206-211
    • Becker, K.1    Kindrick, D.2    Relton, J.3    Harlan, J.4    Winn, R.5
  • 87
    • 0030871256 scopus 로고    scopus 로고
    • Prevention of cerebral edema and infarct in cerebral reperfusion injury by an antibody to interleukin-8
    • Matsumoto, T., Ikeda, K., Mukaida, N., Harada, A., Matsumoto, Y., Yamashita, J., Matsushima, K. (1997) Prevention of cerebral edema and infarct in cerebral reperfusion injury by an antibody to interleukin-8. Lab. Invest. 77, 119-125.
    • (1997) Lab. Invest. , vol.77 , pp. 119-125
    • Matsumoto, T.1    Ikeda, K.2    Mukaida, N.3    Harada, A.4    Matsumoto, Y.5    Yamashita, J.6    Matsushima, K.7
  • 88
    • 0028893614 scopus 로고
    • Expression of monocyte chemoattractant protein-1 and macrophage inflammatory protein-1 after focal cerebral ischemia in the rat
    • Kim, J. S., Gautam, S. C., Chopp, M., Zaloga, C., Jones, M. L., Ward, P. A., Welch, K. M. (1995) Expression of monocyte chemoattractant protein-1 and macrophage inflammatory protein-1 after focal cerebral ischemia in the rat. J. Neuroimmunol. 56, 127-134.
    • (1995) J. Neuroimmunol. , vol.56 , pp. 127-134
    • Kim, J.S.1    Gautam, S.C.2    Chopp, M.3    Zaloga, C.4    Jones, M.L.5    Ward, P.A.6    Welch, K.M.7
  • 90
    • 34247874753 scopus 로고    scopus 로고
    • Absence of the chemokine receptor CCR2 protects against cerebral ischemia/reperfusion injury in mice
    • Dimitrijevic, O. B., Stamatovic, S. M., Keep, R. F., Andjelkovic, A. V. (2007) Absence of the chemokine receptor CCR2 protects against cerebral ischemia/reperfusion injury in mice. Stroke 38, 1345-1353.
    • (2007) Stroke , vol.38 , pp. 1345-1353
    • Dimitrijevic, O.B.1    Stamatovic, S.M.2    Keep, R.F.3    Andjelkovic, A.V.4
  • 92
    • 47249141913 scopus 로고    scopus 로고
    • Enhanced expression of the CXCl12/SDF-1 chemokine receptor CXCR7 after cerebral ischemia in the rat brain
    • Schönemeier, B., Schulz, S., Hoellt, V., Stumm, R. (2008) Enhanced expression of the CXCl12/SDF-1 chemokine receptor CXCR7 after cerebral ischemia in the rat brain. J. Neuroimmunol. 198, 39-45.
    • (2008) J. Neuroimmunol. , vol.198 , pp. 39-45
    • Schönemeier, B.1    Schulz, S.2    Hoellt, V.3    Stumm, R.4
  • 94
    • 0034125046 scopus 로고    scopus 로고
    • Identification and molecular characterization of rat CXCR3: Receptor expression and interferon-inducible protein-10 binding are increased in focal stroke
    • Wang, X., Li, X., Schmidt, D. B., Foley, J. J., Barone, F. C., Ames, R. S., Sarau, H. M. (2000) Identification and molecular characterization of rat CXCR3: receptor expression and interferon-inducible protein-10 binding are increased in focal stroke. Mol. Pharmacol. 57, 1190-1198.
    • (2000) Mol. Pharmacol. , vol.57 , pp. 1190-1198
    • Wang, X.1    Li, X.2    Schmidt, D.B.3    Foley, J.J.4    Barone, F.C.5    Ames, R.S.6    Sarau, H.M.7
  • 96
    • 4744345813 scopus 로고    scopus 로고
    • Differential inside-out activation of β2-integrins by leukotriene B4 and fMLP in human neutrophils
    • Patcha, V., Wigren, J., Winberg, M. E., Rasmusson, B., Li, J., Särndahl, E. (2004) Differential inside-out activation of β2-integrins by leukotriene B4 and fMLP in human neutrophils. Exp. Cell Res. 300, 308-319.
    • (2004) Exp. Cell Res. , vol.300 , pp. 308-319
    • Patcha, V.1    Wigren, J.2    Winberg, M.E.3    Rasmusson, B.4    Li, J.5    Särndahl, E.6
  • 97
    • 0037530357 scopus 로고    scopus 로고
    • Firm adhesion of neutrophils to cerebral vascular endothelium "in vivo": A role for cys-leukotrienes
    • Carnini, C., Constantin, G., Rossi, B., De Curtis, M., Folco, G. (2003) Firm adhesion of neutrophils to cerebral vascular endothelium "in vivo": a role for cys-leukotrienes. Adv. Exp. Med. Biol. 525, 35-38.
    • (2003) Adv. Exp. Med. Biol. , vol.525 , pp. 35-38
    • Carnini, C.1    Constantin, G.2    Rossi, B.3    de Curtis, M.4    Folco, G.5
  • 99
    • 76149083904 scopus 로고    scopus 로고
    • Leukotriene D4 activates β2-integrin adhesion in human polymorphonuclear leukocytes
    • Meliton, A. Y., Muñoz, N. M., Osan, C. M., Meliton, L. N., Leff, A. R. (2010) Leukotriene D4 activates β2-integrin adhesion in human polymorphonuclear leukocytes. Eur. Respir. J. 35, 402-409.
    • (2010) Eur. Respir. J. , vol.35 , pp. 402-409
    • Meliton, A.Y.1    Muñoz, N.M.2    Osan, C.M.3    Meliton, L.N.4    Leff, A.R.5
  • 100
    • 0030863206 scopus 로고    scopus 로고
    • Effects of combined glutamate and platelet-activating factor inhibition on the outcome of focal cerebral ischemia-an initial screening study
    • Aspey, B. S., Alp, M. S., Patel, Y., Harrison, M. J. (1997) Effects of combined glutamate and platelet-activating factor inhibition on the outcome of focal cerebral ischemia-an initial screening study. Metab. Brain Dis. 12, 237-249.
    • (1997) Metab. Brain Dis. , vol.12 , pp. 237-249
    • Aspey, B.S.1    Alp, M.S.2    Patel, Y.3    Harrison, M.J.4
  • 101
    • 56349131188 scopus 로고    scopus 로고
    • LAU-0901, a novel platelet-activating factor antagonist, is highly neuroprotective in cerebral ischemia
    • Belayev, L., Khoutorova, L., Atkins, K., Gordon, W. C., Alvarez-Builla, J., Bazan, N. G. (2008) LAU-0901, a novel platelet-activating factor antagonist, is highly neuroprotective in cerebral ischemia. Exp. Neurol. 214, 253-258.
    • (2008) Exp. Neurol. , vol.214 , pp. 253-258
    • Belayev, L.1    Khoutorova, L.2    Atkins, K.3    Gordon, W.C.4    Alvarez-Builla, J.5    Bazan, N.G.6
  • 102
    • 0032571139 scopus 로고    scopus 로고
    • Involvement of Mac-1-mediated adherence and sphingosine 1-phosphate in survival of phorbol ester-treated U937 cells
    • Hamada, K., Nakamura, H., Oda, T., Hirano, T., Shimizu, N., Utiyama, H. (1998) Involvement of Mac-1-mediated adherence and sphingosine 1-phosphate in survival of phorbol ester-treated U937 cells. Biochem. Biophys. Res. Commun. 244, 745-750.
    • (1998) Biochem. Biophys. Res. Commun. , vol.244 , pp. 745-750
    • Hamada, K.1    Nakamura, H.2    Oda, T.3    Hirano, T.4    Shimizu, N.5    Utiyama, H.6
  • 104
    • 77449106966 scopus 로고    scopus 로고
    • Activation of sphingosine 1-phosphate receptor-1 by FTY720 is neuroprotective after ischemic stroke in rats
    • Hasegawa, Y., Suzuki, H., Sozen, T., Rolland, W., Zhang, J. H. (2010) Activation of sphingosine 1-phosphate receptor-1 by FTY720 is neuroprotective after ischemic stroke in rats. Stroke 41, 368-374.
    • (2010) Stroke , vol.41 , pp. 368-374
    • Hasegawa, Y.1    Suzuki, H.2    Sozen, T.3    Rolland, W.4    Zhang, J.H.5
  • 109
    • 0029808409 scopus 로고    scopus 로고
    • Endothelial ICAM-1 expression associated with inflammatory cell response in human ischemic stroke
    • Lindsberg, P. J., Carpen, O., Paetau, A., Karjalainen-Lindsberg, M. L., Kaste, M. (1996) Endothelial ICAM-1 expression associated with inflammatory cell response in human ischemic stroke. Circulation 94, 939-945.
    • (1996) Circulation , vol.94 , pp. 939-945
    • Lindsberg, P.J.1    Carpen, O.2    Paetau, A.3    Karjalainen-Lindsberg, M.L.4    Kaste, M.5
  • 110
    • 0027196122 scopus 로고
    • Circulating intercellular adhesion molecule-1 levels and neutrophil adhesion in stroke
    • Clark, W. M., Coull, B. M., Briley, D. P., Mainolfi, E., Rothlein, R. (1993) Circulating intercellular adhesion molecule-1 levels and neutrophil adhesion in stroke. J. Neuroimmunol. 44, 123-125.
    • (1993) J. Neuroimmunol. , vol.44 , pp. 123-125
    • Clark, W.M.1    Coull, B.M.2    Briley, D.P.3    Mainolfi, E.4    Rothlein, R.5
  • 111
    • 27944487853 scopus 로고    scopus 로고
    • Predictive value of soluble intercellular adhesion molecule-1 for risk of ischemic events in individuals with cerebrovascular disease
    • Ehrensperger, E., Minuk, J., Durcan, L., Mackey, A., Wolfson, C., Fontaine, A. M., Cote, R. (2005) Predictive value of soluble intercellular adhesion molecule-1 for risk of ischemic events in individuals with cerebrovascular disease. Cerebrovasc. Dis. 20, 456-462.
    • (2005) Cerebrovasc. Dis. , vol.20 , pp. 456-462
    • Ehrensperger, E.1    Minuk, J.2    Durcan, L.3    Mackey, A.4    Wolfson, C.5    Fontaine, A.M.6    Cote, R.7
  • 112
    • 0037812204 scopus 로고    scopus 로고
    • Cerebrospinal fluid and plasma concentration of soluble intercellular adhesion molecule 1, vascular cell adhesion molecule 1 and endothelial leukocyte adhesion molecule in patients with acute ischemic brain disease
    • Selaković, V., Colić, M., Jovanović, M., Raicević, R., Jovicić, A. (2003) Cerebrospinal fluid and plasma concentration of soluble intercellular adhesion molecule 1, vascular cell adhesion molecule 1 and endothelial leukocyte adhesion molecule in patients with acute ischemic brain disease. Vojnosanit. Pregl. 60, 139-146.
    • (2003) Vojnosanit. Pregl. , vol.60 , pp. 139-146
    • Selaković, V.1    Colić, M.2    Jovanović, M.3    Raicević, R.4    Jovicić, A.5
  • 114
    • 0033557749 scopus 로고    scopus 로고
    • Anti-ICAM-1 monoclonal antibody R6.5 (enlimomab) promotes activation of neutrophils in whole blood
    • Vuorte, J., Lindsberg, P. J., Kaste, M., Meri, S., Jansson, S. E., Rothlein, R., Repo, H. (1999) Anti-ICAM-1 monoclonal antibody R6.5 (enlimomab) promotes activation of neutrophils in whole blood. J. Immunol. 162, 2353-2357.
    • (1999) J. Immunol. , vol.162 , pp. 2353-2357
    • Vuorte, J.1    Lindsberg, P.J.2    Kaste, M.3    Meri, S.4    Jansson, S.E.5    Rothlein, R.6    Repo, H.7
  • 115
    • 0035164475 scopus 로고    scopus 로고
    • Examination of several potential mechanisms for the negative outcome in a clinical stroke trial of enlimomab, a murine anti-human intercellular adhesion molecule-1 antibody: A bedside-to-bench study
    • Furuya, K., Takeda, H., Azhar, S., McCarron, R. M., Chen, Y., Ruetzler, C. A., Wolcott, K. M., DeGraba, T. J., Rothlein, R., Hugli, T. E., del Zoppo, G. J., Hallenbeck, J. M. (2001) Examination of several potential mechanisms for the negative outcome in a clinical stroke trial of enlimomab, a murine anti-human intercellular adhesion molecule-1 antibody: a bedside-to-bench study. Stroke 32, 2665-2674.
    • (2001) Stroke , vol.32 , pp. 2665-2674
    • Furuya, K.1    Takeda, H.2    Azhar, S.3    McCarron, R.M.4    Chen, Y.5    Ruetzler, C.A.6    Wolcott, K.M.7    DeGraba, T.J.8    Rothlein, R.9    Hugli, T.E.10    del Zoppo, G.J.11    Hallenbeck, J.M.12
  • 116
    • 0037010009 scopus 로고    scopus 로고
    • The effect of blockade of the CD11/CD18 integrin receptor on infarct size in patients with acute myocardial infarction treated with direct angioplasty: The results of the HALT-MI study
    • Faxon, D. P., Gibbons, R. J., Chronos, N. A., Gurbel, P. A., Sheehan, F. (2002) The effect of blockade of the CD11/CD18 integrin receptor on infarct size in patients with acute myocardial infarction treated with direct angioplasty: the results of the HALT-MI study. J. Am. Coll. Cardiol. 40, 1199-1204.
    • (2002) J. Am. Coll. Cardiol. , vol.40 , pp. 1199-1204
    • Faxon, D.P.1    Gibbons, R.J.2    Chronos, N.A.3    Gurbel, P.A.4    Sheehan, F.5
  • 117
    • 0036369590 scopus 로고    scopus 로고
    • Anti-leukocyte antibodies: LeukArrest (Hu23F2G) and enlimomab (R6.5) in acute stroke
    • Becker, K. J. (2002) Anti-leukocyte antibodies: LeukArrest (Hu23F2G) and enlimomab (R6.5) in acute stroke. Curr. Med. Res. Opin. 18 (Suppl. 2), s18-s22.
    • (2002) Curr. Med. Res. Opin. , vol.18 , Issue.SUPPL. 2
    • Becker, K.J.1
  • 118
    • 0242694372 scopus 로고    scopus 로고
    • Acute stroke therapy by inhibition of neutrophils (ASTIN): An adaptive dose-response study of UK-279,276 in acute ischemic stroke
    • Krams, M., Lees, K. R., Hacke, W., Grieve, A. P., Orgogozo, J. M., Ford, G. A. (2003) Acute stroke therapy by inhibition of neutrophils (ASTIN): an adaptive dose-response study of UK-279,276 in acute ischemic stroke. Stroke 34, 2543-2548.
    • (2003) Stroke , vol.34 , pp. 2543-2548
    • Krams, M.1    Lees, K.R.2    Hacke, W.3    Grieve, A.P.4    Orgogozo, J.M.5    Ford, G.A.6
  • 119
    • 29144533904 scopus 로고    scopus 로고
    • CD18 is required for optimal development and function of CD4+CD25+ T regulatory cells
    • Marski, M., Kandula, S., Turner, J. R., Abraham, C. (2005) CD18 is required for optimal development and function of CD4+CD25+ T regulatory cells. J. Immunol. 175, 7889-7897.
    • (2005) J. Immunol. , vol.175 , pp. 7889-7897
    • Marski, M.1    Kandula, S.2    Turner, J.R.3    Abraham, C.4
  • 120
    • 67349179096 scopus 로고    scopus 로고
    • LFA-1 is critical for regulatory T cell homeostasis and function
    • Wohler, J., Bullard, D., Schoeb, T., Barnum, S. (2009) LFA-1 is critical for regulatory T cell homeostasis and function. Mol. Immunol. 46, 2424-2428.
    • (2009) Mol. Immunol. , vol.46 , pp. 2424-2428
    • Wohler, J.1    Bullard, D.2    Schoeb, T.3    Barnum, S.4
  • 122
    • 34548133584 scopus 로고    scopus 로고
    • Multiple sclerosis: A complicated picture of autoimmunity
    • McFarland, H. F., Martin, R. (2007) Multiple sclerosis: a complicated picture of autoimmunity. Nat. Immunol. 8, 913-919.
    • (2007) Nat. Immunol. , vol.8 , pp. 913-919
    • McFarland, H.F.1    Martin, R.2
  • 123
    • 0029011440 scopus 로고
    • Blood-brain barrier disruption on contrast-enhanced MRI in patients with mild relapsing-remitting multiple sclerosis: Relationship to course, gender, and age
    • Stone, L. A., Smith, M. E., Albert, P. S., Bash, C. N., Maloni, H., Frank, J. A., McFarland, H. F. (1995) Blood-brain barrier disruption on contrast-enhanced MRI in patients with mild relapsing-remitting multiple sclerosis: relationship to course, gender, and age. Neurology 45, 1122-1126.
    • (1995) Neurology , vol.45 , pp. 1122-1126
    • Stone, L.A.1    Smith, M.E.2    Albert, P.S.3    Bash, C.N.4    Maloni, H.5    Frank, J.A.6    McFarland, H.F.7
  • 124
    • 0018098390 scopus 로고
    • Chronic relapsing EAE. Time course of neurological symptoms and pathology
    • Lassmann, H., Wisniewski, H. M. (1978) Chronic relapsing EAE. Time course of neurological symptoms and pathology. Acta Neuropathol. 43, 35-42.
    • (1978) Acta Neuropathol. , vol.43 , pp. 35-42
    • Lassmann, H.1    Wisniewski, H.M.2
  • 125
    • 0018423159 scopus 로고
    • Acute experimental allergic encephalomyelitis. Myelin basic protein-reactive T cells in the circulation and in meningeal infiltrates
    • Traugott, U., Raine, C. S. (1979) Acute experimental allergic encephalomyelitis. Myelin basic protein-reactive T cells in the circulation and in meningeal infiltrates. J. Neurol. Sci. 42, 331-336.
    • (1979) J. Neurol. Sci. , vol.42 , pp. 331-336
    • Traugott, U.1    Raine, C.S.2
  • 126
    • 0028169182 scopus 로고
    • Identification of CD4-CD8-α β T cells in the subarachnoid space of rats with experimental autoimmune encephalomyelitis. A possible route by which effector cells invade the lesions
    • Tsuchida, M., Hanawa, H., Hirahara, H., Watanabe, H., Matsumoto, Y., Sekikawa, H., Abo, T. (1994) Identification of CD4-CD8-α β T cells in the subarachnoid space of rats with experimental autoimmune encephalomyelitis. A possible route by which effector cells invade the lesions. Immunology 81, 420-427.
    • (1994) Immunology , vol.81 , pp. 420-427
    • Tsuchida, M.1    Hanawa, H.2    Hirahara, H.3    Watanabe, H.4    Matsumoto, Y.5    Sekikawa, H.6    Abo, T.7
  • 127
    • 0142259710 scopus 로고    scopus 로고
    • Three or more routes for leukocyte migration into the central nervous system
    • Ransohoff, R. M., Kivisakk, P., Kidd, G. (2003) Three or more routes for leukocyte migration into the central nervous system. Nat. Rev. Immunol. 3, 569-581.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 569-581
    • Ransohoff, R.M.1    Kivisakk, P.2    Kidd, G.3
  • 129
    • 34247108119 scopus 로고    scopus 로고
    • Time course and distribution of inflammatory and neurodegenerative events suggest structural bases for the pathogenesis of experimental autoimmune encephalomyelitis
    • Brown, D. A., Sawchenko, P. E. (2007) Time course and distribution of inflammatory and neurodegenerative events suggest structural bases for the pathogenesis of experimental autoimmune encephalomyelitis. J. Comp. Neurol. 502, 236-260.
    • (2007) J. Comp. Neurol. , vol.502 , pp. 236-260
    • Brown, D.A.1    Sawchenko, P.E.2
  • 131
    • 0030848142 scopus 로고    scopus 로고
    • Is the pial microvessel a good model for blood-brain barrier studies?
    • Allt, G., Lawrenson, J. G. (1997) Is the pial microvessel a good model for blood-brain barrier studies? Brain Res. Brain Res. Rev. 24, 67-76.
    • (1997) Brain Res. Brain Res. Rev. , vol.24 , pp. 67-76
    • Allt, G.1    Lawrenson, J.G.2
  • 132
    • 67349216357 scopus 로고    scopus 로고
    • Autoimmune T cell responses in the central nervous system
    • Goverman, J. (2009) Autoimmune T cell responses in the central nervous system. Nat. Rev. Immunol. 9, 393-407.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 393-407
    • Goverman, J.1
  • 134
    • 0032964119 scopus 로고    scopus 로고
    • Disproportionate recruitment of CD8+ T cells into the central nervous system by professional antigen-presenting cells
    • Carson, M. J., Reilly, C. R., Sutcliffe, J. G., Lo, D. (1999) Disproportionate recruitment of CD8+ T cells into the central nervous system by professional antigen-presenting cells. Am. J. Pathol. 154, 481-494.
    • (1999) Am. J. Pathol. , vol.154 , pp. 481-494
    • Carson, M.J.1    Reilly, C.R.2    Sutcliffe, J.G.3    Lo, D.4
  • 135
    • 0035801332 scopus 로고    scopus 로고
    • A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis
    • Huseby, E. S., Liggitt, D., Brabb, T., Schnabel, B., Ohlen, C., Goverman, J. (2001) A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis. J. Exp. Med. 194, 669-676.
    • (2001) J. Exp. Med. , vol.194 , pp. 669-676
    • Huseby, E.S.1    Liggitt, D.2    Brabb, T.3    Schnabel, B.4    Ohlen, C.5    Goverman, J.6
  • 136
    • 0035877190 scopus 로고    scopus 로고
    • Myelin antigen-specific CD8+ T cells are encephalitogenic and produce severe disease in C57BL/6 mice
    • Sun, D., Whitaker, J. N., Huang, Z., Liu, D., Coleclough, C., Wekerle, H., Raine, C. S. (2001) Myelin antigen-specific CD8+ T cells are encephalitogenic and produce severe disease in C57BL/6 mice. J. Immunol. 166, 7579-7587.
    • (2001) J. Immunol. , vol.166 , pp. 7579-7587
    • Sun, D.1    Whitaker, J.N.2    Huang, Z.3    Liu, D.4    Coleclough, C.5    Wekerle, H.6    Raine, C.S.7
  • 137
    • 0034618094 scopus 로고    scopus 로고
    • Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction
    • Babbe, H., Roers, A., Waisman, A., Lassmann, H., Goebels, N., Hohlfeld, R., Friese, M., Schroder, R., Deckert, M., Schmidt, S., Ravid, R., Rajewsky, K. (2000) Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction. J. Exp. Med. 192, 393-404.
    • (2000) J. Exp. Med. , vol.192 , pp. 393-404
    • Babbe, H.1    Roers, A.2    Waisman, A.3    Lassmann, H.4    Goebels, N.5    Hohlfeld, R.6    Friese, M.7    Schroder, R.8    Deckert, M.9    Schmidt, S.10    Ravid, R.11    Rajewsky, K.12
  • 140
    • 0033802454 scopus 로고    scopus 로고
    • In situ tolerance within the central nervous system as a mechanism for preventing autoimmunity
    • Brabb, T., von Dassow, P., Ordonez, N., Schnabel, B., Duke, B., Goverman, J. (2000) In situ tolerance within the central nervous system as a mechanism for preventing autoimmunity. J. Exp. Med. 192, 871-880.
    • (2000) J. Exp. Med. , vol.192 , pp. 871-880
    • Brabb, T.1    von Dassow, P.2    Ordonez, N.3    Schnabel, B.4    Duke, B.5    Goverman, J.6
  • 141
    • 0032981648 scopus 로고    scopus 로고
    • Adhesion molecule expression and regulation on cells of the central nervous system
    • Lee, S. J., Benveniste, E. N. (1999) Adhesion molecule expression and regulation on cells of the central nervous system. J. Neuroimmunol. 98, 77-88.
    • (1999) J. Neuroimmunol. , vol.98 , pp. 77-88
    • Lee, S.J.1    Benveniste, E.N.2
  • 142
    • 24144446150 scopus 로고    scopus 로고
    • Plasma levels of soluble adhesion molecules sPECAM-1, sP-selectin and sE-selectin are associated with relapsing-remitting disease course of multiple sclerosis
    • Kuenz, B., Lutterotti, A., Khalil, M., Ehling, R., Gneiss, C., Deisenhammer, F., Reindl, M., Berger, T. (2005) Plasma levels of soluble adhesion molecules sPECAM-1, sP-selectin and sE-selectin are associated with relapsing-remitting disease course of multiple sclerosis. J. Neuroimmunol. 167, 143-149.
    • (2005) J. Neuroimmunol. , vol.167 , pp. 143-149
    • Kuenz, B.1    Lutterotti, A.2    Khalil, M.3    Ehling, R.4    Gneiss, C.5    Deisenhammer, F.6    Reindl, M.7    Berger, T.8
  • 143
    • 70350721913 scopus 로고    scopus 로고
    • Peripheral blood CD4+ T lymphocytes from multiple sclerosis patients are characterized by higher PSGL-1 expression and transmigration capacity across a human blood-brain barrier-derived endothelial cell line
    • Bahbouhi, B., Berthelot, L., Pettre, S., Michel, L., Wiertlewski, S., Weksler, B., Romero, I. A., Miller, F., Couraud, P. O., Brouard, S., Laplaud, D. A., Soulillou, J. P. (2009) Peripheral blood CD4+ T lymphocytes from multiple sclerosis patients are characterized by higher PSGL-1 expression and transmigration capacity across a human blood-brain barrier-derived endothelial cell line. J. Leukoc. Biol. 86, 1049-1063.
    • (2009) J. Leukoc. Biol. , vol.86 , pp. 1049-1063
    • Bahbouhi, B.1    Berthelot, L.2    Pettre, S.3    Michel, L.4    Wiertlewski, S.5    Weksler, B.6    Romero, I.A.7    Miller, F.8    Couraud, P.O.9    Brouard, S.10    Laplaud, D.A.11    Soulillou, J.P.12
  • 144
    • 0037100456 scopus 로고    scopus 로고
    • Overlapping roles of P-selectin and α 4 integrin to recruit leukocytes to the central nervous system in experimental autoimmune encephalomyelitis
    • Kerfoot, S. M., Kubes, P. (2002) Overlapping roles of P-selectin and α 4 integrin to recruit leukocytes to the central nervous system in experimental autoimmune encephalomyelitis. J. Immunol. 169, 1000-1006.
    • (2002) J. Immunol. , vol.169 , pp. 1000-1006
    • Kerfoot, S.M.1    Kubes, P.2
  • 145
    • 33646468932 scopus 로고    scopus 로고
    • Reevaluation of P-selectin and α 4 integrin as targets for the treatment of experimental autoimmune encephalomyelitis
    • Kerfoot, S. M., Norman, M. U., Lapointe, B. M., Bonder, C. S., Zbytnuik, L., Kubes, P. (2006) Reevaluation of P-selectin and α 4 integrin as targets for the treatment of experimental autoimmune encephalomyelitis. J. Immunol. 176, 6225-6234.
    • (2006) J. Immunol. , vol.176 , pp. 6225-6234
    • Kerfoot, S.M.1    Norman, M.U.2    Lapointe, B.M.3    Bonder, C.S.4    Zbytnuik, L.5    Kubes, P.6
  • 146
    • 0034123924 scopus 로고    scopus 로고
    • Differential adhesion molecule requirements for immune surveillance and inflammatory recruitment
    • Carrithers, M. D., Visintin, I., Kang, S. J., Janeway Jr., C. A. (2000) Differential adhesion molecule requirements for immune surveillance and inflammatory recruitment. Brain 123, 1092-1101.
    • (2000) Brain , vol.123 , pp. 1092-1101
    • Carrithers, M.D.1    Visintin, I.2    Kang, S.J.3    Janeway Jr., C.A.4
  • 147
    • 0032744877 scopus 로고    scopus 로고
    • CD44 is involved in selective leucocyte extravasation during inflammatory central nervous system disease
    • Brennan, F. R., O'Neill, J. K., Allen, S. J., Butter, C., Nuki, G., Baker, D. (1999) CD44 is involved in selective leucocyte extravasation during inflammatory central nervous system disease. Immunology 98, 427-435.
    • (1999) Immunology , vol.98 , pp. 427-435
    • Brennan, F.R.1    O'Neill, J.K.2    Allen, S.J.3    Butter, C.4    Nuki, G.5    Baker, D.6
  • 148
    • 0030726193 scopus 로고    scopus 로고
    • E-and P-selectin are not involved in the recruitment of inflammatory cells across the blood-brain barrier in experimental autoimmune encephalomyelitis
    • Engelhardt, B., Vestweber, D., Hallmann, R., Schulz, M. (1997) E-and P-selectin are not involved in the recruitment of inflammatory cells across the blood-brain barrier in experimental autoimmune encephalomyelitis. Blood 90, 4459-4472.
    • (1997) Blood , vol.90 , pp. 4459-4472
    • Engelhardt, B.1    Vestweber, D.2    Hallmann, R.3    Schulz, M.4
  • 149
    • 40049095589 scopus 로고    scopus 로고
    • E-and P-selectin are not required for the development of experimental autoimmune encephalomyelitis in C57BL/6 and SJL mice
    • Döring, A., Wild, M., Vestweber, D., Deutsch, U., Engelhardt, B. (2007) E-and P-selectin are not required for the development of experimental autoimmune encephalomyelitis in C57BL/6 and SJL mice. J. Immunol. 179, 8470-8479.
    • (2007) J. Immunol. , vol.179 , pp. 8470-8479
    • Döring, A.1    Wild, M.2    Vestweber, D.3    Deutsch, U.4    Engelhardt, B.5
  • 150
    • 23244449103 scopus 로고    scopus 로고
    • P-selectin glycoprotein ligand 1 is not required for the development of experimental autoimmune encephalomyelitis in SJL and C57BL/6 mice
    • Engelhardt, B., Kempe, B., Merfeld-Clauss, S., Laschinger, M., Furie, B., Wild, M. K., Vestweber, D. (2005) P-selectin glycoprotein ligand 1 is not required for the development of experimental autoimmune encephalomyelitis in SJL and C57BL/6 mice. J. Immunol. 175, 1267-1275.
    • (2005) J. Immunol. , vol.175 , pp. 1267-1275
    • Engelhardt, B.1    Kempe, B.2    Merfeld-Clauss, S.3    Laschinger, M.4    Furie, B.5    Wild, M.K.6    Vestweber, D.7
  • 151
    • 23044481655 scopus 로고    scopus 로고
    • PSGL-1 is not required for development of experimental autoimmune encephalomyelitis
    • Osmers, I., Bullard, D. C., Barnum, S. R. (2005) PSGL-1 is not required for development of experimental autoimmune encephalomyelitis. J. Neuroimmunol. 166, 193-196.
    • (2005) J. Neuroimmunol. , vol.166 , pp. 193-196
    • Osmers, I.1    Bullard, D.C.2    Barnum, S.R.3
  • 156
    • 0028283232 scopus 로고
    • Evidence for involvement of ICAM-1 and VCAM-1 in lymphocyte interaction with endothelium in experimental autoimmune encephalomyelitis in the central nervous system in the SJL/J mouse
    • Steffen, B. J., Butcher, E. C., Engelhardt, B. (1994) Evidence for involvement of ICAM-1 and VCAM-1 in lymphocyte interaction with endothelium in experimental autoimmune encephalomyelitis in the central nervous system in the SJL/J mouse. Am. J. Pathol. 145, 189-201.
    • (1994) Am. J. Pathol. , vol.145 , pp. 189-201
    • Steffen, B.J.1    Butcher, E.C.2    Engelhardt, B.3
  • 157
    • 0025168906 scopus 로고
    • Homing to central nervous system vasculature by antigen-specific lymphocytes. II. Lymphocyte/endothelial cell adhesion during the initial stages of autoimmune demyelination
    • Raine, C. S., Cannella, B., Duijvestijn, A. M., Cross, A. H. (1990) Homing to central nervous system vasculature by antigen-specific lymphocytes. II. Lymphocyte/endothelial cell adhesion during the initial stages of autoimmune demyelination. Lab. Invest. 63, 476-489.
    • (1990) Lab. Invest. , vol.63 , pp. 476-489
    • Raine, C.S.1    Cannella, B.2    Duijvestijn, A.M.3    Cross, A.H.4
  • 158
    • 0030859353 scopus 로고    scopus 로고
    • Longitudinal study of soluble adhesion molecules in multiple sclerosis: Correlation with gadolinium enhanced magnetic resonance imaging
    • Giovannoni, G., Lai, M., Thorpe, J., Kidd, D., Chamoun, V., Thompson, A. J., Miller, D. H., Feldmann, M., Thompson, E. J. (1997) Longitudinal study of soluble adhesion molecules in multiple sclerosis: correlation with gadolinium enhanced magnetic resonance imaging. Neurology 48, 1557-1565.
    • (1997) Neurology , vol.48 , pp. 1557-1565
    • Giovannoni, G.1    Lai, M.2    Thorpe, J.3    Kidd, D.4    Chamoun, V.5    Thompson, A.J.6    Miller, D.H.7    Feldmann, M.8    Thompson, E.J.9
  • 159
    • 0028004011 scopus 로고
    • Serial analysis of circulating adhesion molecules and TNF receptor in serum from patients with multiple sclerosis: CICAM-1 is an indicator for relapse
    • Rieckmann, P., Martin, S., Weichselbraun, I., Albrecht, M., Kitze, B., Weber, T., Tumani, H., Broocks, A., Luer, W., Helwig, A., et al. (1994) Serial analysis of circulating adhesion molecules and TNF receptor in serum from patients with multiple sclerosis: cICAM-1 is an indicator for relapse. Neurology 44, 2367-2372.
    • (1994) Neurology , vol.44 , pp. 2367-2372
    • Rieckmann, P.1    Martin, S.2    Weichselbraun, I.3    Albrecht, M.4    Kitze, B.5    Weber, T.6    Tumani, H.7    Broocks, A.8    Luer, W.9    Helwig, A.10
  • 160
    • 0029112447 scopus 로고
    • Circulating adhesion molecules and tumor necrosis factor receptor in multiple sclerosis: Correlation with magnetic resonance imaging
    • Hartung, H. P., Reiners, K., Archelos, J. J., Michels, M., Seeldrayers, P., Heidenreich, F., Pflughaupt, K. W., Toyka, K. V. (1995) Circulating adhesion molecules and tumor necrosis factor receptor in multiple sclerosis: correlation with magnetic resonance imaging. Ann. Neurol. 38, 186-193.
    • (1995) Ann. Neurol. , vol.38 , pp. 186-193
    • Hartung, H.P.1    Reiners, K.2    Archelos, J.J.3    Michels, M.4    Seeldrayers, P.5    Heidenreich, F.6    Pflughaupt, K.W.7    Toyka, K.V.8
  • 161
    • 0031056637 scopus 로고    scopus 로고
    • Soluble adhesion molecules (sVCAM-1 and sICAM-1) in cerebrospinal fluid and serum correlate with MRI activity in multiple sclerosis
    • Rieckmann, P., Altenhofen, B., Riegel, A., Baudewig, J., Felgenhauer, K. (1997) Soluble adhesion molecules (sVCAM-1 and sICAM-1) in cerebrospinal fluid and serum correlate with MRI activity in multiple sclerosis. Ann. Neurol. 41, 326-333.
    • (1997) Ann. Neurol. , vol.41 , pp. 326-333
    • Rieckmann, P.1    Altenhofen, B.2    Riegel, A.3    Baudewig, J.4    Felgenhauer, K.5
  • 162
    • 0032705907 scopus 로고    scopus 로고
    • Increased serum levels of soluble PECAM-1 in multiple sclerosis patients with brain gadolinium-enhancing lesions
    • Losy, J., Niezgoda, A., Wender, M. (1999) Increased serum levels of soluble PECAM-1 in multiple sclerosis patients with brain gadolinium-enhancing lesions. J. Neuroimmunol. 99, 169-172.
    • (1999) J. Neuroimmunol. , vol.99 , pp. 169-172
    • Losy, J.1    Niezgoda, A.2    Wender, M.3
  • 163
    • 85047682713 scopus 로고    scopus 로고
    • α4-Integrin-VCAM-1 binding mediates G protein-independent capture of encephalitogenic T cell blasts to CNS white matter microvessels
    • Vajkoczy, P., Laschinger, M., Engelhardt, B. (2001) α4-Integrin-VCAM-1 binding mediates G protein-independent capture of encephalitogenic T cell blasts to CNS white matter microvessels. J. Clin. Invest. 108, 557-565.
    • (2001) J. Clin. Invest. , vol.108 , pp. 557-565
    • Vajkoczy, P.1    Laschinger, M.2    Engelhardt, B.3
  • 164
    • 0026506799 scopus 로고
    • Prevention of experimental autoimmune encephalomyelitis by antibodies against α 4 β 1 integrin
    • Yednock, T. A., Cannon, C., Fritz, L. C., Sanchez-Madrid, F., Steinman, L., Karin, N. (1992) Prevention of experimental autoimmune encephalomyelitis by antibodies against α 4 β 1 integrin. Nature 356, 63-66.
    • (1992) Nature , vol.356 , pp. 63-66
    • Yednock, T.A.1    Cannon, C.2    Fritz, L.C.3    Sanchez-Madrid, F.4    Steinman, L.5    Karin, N.6
  • 165
    • 0027529932 scopus 로고
    • Surface expression of α 4 integrin by CD4 T cells is required for their entry into brain parenchyma
    • Baron, J. L., Madri, J. A., Ruddle, N. H., Hashim, G., Janeway Jr., C. A. (1993) Surface expression of α 4 integrin by CD4 T cells is required for their entry into brain parenchyma. J. Exp. Med. 177, 57-68.
    • (1993) J. Exp. Med. , vol.177 , pp. 57-68
    • Baron, J.L.1    Madri, J.A.2    Ruddle, N.H.3    Hashim, G.4    Janeway Jr., C.A.5
  • 166
    • 0028987311 scopus 로고
    • A monoclonal antibody to α 4 integrin suppresses and reverses active experimental allergic encephalomyelitis
    • Kent, S. J., Karlik, S. J., Cannon, C., Hines, D. K., Yednock, T. A., Fritz, L. C., Horner, H. C. (1995) A monoclonal antibody to α 4 integrin suppresses and reverses active experimental allergic encephalomyelitis. J. Neuroimmunol. 58, 1-10.
    • (1995) J. Neuroimmunol. , vol.58 , pp. 1-10
    • Kent, S.J.1    Karlik, S.J.2    Cannon, C.3    Hines, D.K.4    Yednock, T.A.5    Fritz, L.C.6    Horner, H.C.7
  • 167
    • 0029834867 scopus 로고    scopus 로고
    • Evidence for a prolonged role of α 4 integrin throughout active experimental allergic encephalomyelitis
    • Keszthelyi, E., Karlik, S., Hyduk, S., Rice, G. P., Gordon, G., Yednock, T., Horner, H. (1996) Evidence for a prolonged role of α 4 integrin throughout active experimental allergic encephalomyelitis. Neurology 47, 1053-1059.
    • (1996) Neurology , vol.47 , pp. 1053-1059
    • Keszthelyi, E.1    Karlik, S.2    Hyduk, S.3    Rice, G.P.4    Gordon, G.5    Yednock, T.6    Horner, H.7
  • 168
  • 169
    • 0027448726 scopus 로고
    • Anti-adhesion molecule therapy in experimental autoimmune encephalomyelitis
    • Cannella, B., Cross, A. H., Raine, C. S. (1993) Anti-adhesion molecule therapy in experimental autoimmune encephalomyelitis. J. Neuroimmunol. 46, 43-55.
    • (1993) J. Neuroimmunol. , vol.46 , pp. 43-55
    • Cannella, B.1    Cross, A.H.2    Raine, C.S.3
  • 170
    • 0029149732 scopus 로고
    • Antibodies against leukocyte function-associated antigen-1 and against intercellular adhesion molecule-1 together suppress the progression of experimental allergic encephalomyelitis
    • Kobayashi, Y., Kawai, K., Honda, H., Tomida, S., Niimi, N., Tamatani, T., Miyasaka, M., Yoshikai, Y. (1995) Antibodies against leukocyte function-associated antigen-1 and against intercellular adhesion molecule-1 together suppress the progression of experimental allergic encephalomyelitis. Cell. Immunol. 164, 295-305.
    • (1995) Cell. Immunol. , vol.164 , pp. 295-305
    • Kobayashi, Y.1    Kawai, K.2    Honda, H.3    Tomida, S.4    Niimi, N.5    Tamatani, T.6    Miyasaka, M.7    Yoshikai, Y.8
  • 171
    • 0028856219 scopus 로고
    • Both anti-CD11a (LFA-1) and anti-CD11b (MAC-1) therapy delay the onset and diminish the severity of experimental autoimmune encephalomyelitis
    • Gordon, E. J., Myers, K. J., Dougherty, J. P., Rosen, H., Ron, Y. (1995) Both anti-CD11a (LFA-1) and anti-CD11b (MAC-1) therapy delay the onset and diminish the severity of experimental autoimmune encephalomyelitis. J. Neuroimmunol. 62, 153-160.
    • (1995) J. Neuroimmunol. , vol.62 , pp. 153-160
    • Gordon, E.J.1    Myers, K.J.2    Dougherty, J.P.3    Rosen, H.4    Ron, Y.5
  • 172
    • 27744451956 scopus 로고    scopus 로고
    • Critical requirement of CD11b (Mac-1) on T cells and accessory cells for development of experimental autoimmune encephalomyelitis
    • Bullard, D. C., Hu, X., Schoeb, T. R., Axtell, R. C., Raman, C., Barnum, S. R. (2005) Critical requirement of CD11b (Mac-1) on T cells and accessory cells for development of experimental autoimmune encephalomyelitis. J. Immunol. 175, 6327-6333.
    • (2005) J. Immunol. , vol.175 , pp. 6327-6333
    • Bullard, D.C.1    Hu, X.2    Schoeb, T.R.3    Axtell, R.C.4    Raman, C.5    Barnum, S.R.6
  • 173
    • 0033667644 scopus 로고    scopus 로고
    • Prevention of a chronic progressive form of experimental autoimmune encephalomyelitis by an antibody against mucosal addressin cell adhesion molecule-1, given early in the course of disease progression
    • Kanwar, J. R., Kanwar, R. K., Wang, D., Krissansen, G. W. (2000) Prevention of a chronic progressive form of experimental autoimmune encephalomyelitis by an antibody against mucosal addressin cell adhesion molecule-1, given early in the course of disease progression. Immunol. Cell Biol. 78, 641-645.
    • (2000) Immunol. Cell Biol. , vol.78 , pp. 641-645
    • Kanwar, J.R.1    Kanwar, R.K.2    Wang, D.3    Krissansen, G.W.4
  • 175
    • 47249111609 scopus 로고    scopus 로고
    • Chemokine signaling and integrin activation in lymphocyte migration into the inflamed brain
    • Constantin, G. (2008) Chemokine signaling and integrin activation in lymphocyte migration into the inflamed brain. J. Neuroimmunol. 198, 20-26.
    • (2008) J. Neuroimmunol. , vol.198 , pp. 20-26
    • Constantin, G.1
  • 176
    • 0036687120 scopus 로고    scopus 로고
    • Functional expression of the lymphoid chemokines CCL19 (ELC) and CCL 21 (SLC) at the blood-brain barrier suggests their involvement in G-protein-dependent lymphocyte recruitment into the central nervous system during experimental autoimmune encephalomyelitis
    • Alt, C., Laschinger, M., Engelhardt, B. (2002) Functional expression of the lymphoid chemokines CCL19 (ELC) and CCL 21 (SLC) at the blood-brain barrier suggests their involvement in G-protein-dependent lymphocyte recruitment into the central nervous system during experimental autoimmune encephalomyelitis. Eur. J. Immunol. 32, 2133-2144.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 2133-2144
    • Alt, C.1    Laschinger, M.2    Engelhardt, B.3
  • 177
    • 0037248807 scopus 로고    scopus 로고
    • Lymphoid chemokines CCL19 and CCL21 are expressed in the central nervous system during experimental autoimmune encephalomyelitis: Implications for the maintenance of chronic neuroinflammation
    • Columba-Cabezas, S., Serafini, B., Ambrosini, E., Aloisi, F. (2003) Lymphoid chemokines CCL19 and CCL21 are expressed in the central nervous system during experimental autoimmune encephalomyelitis: implications for the maintenance of chronic neuroinflammation. Brain Pathol. 13, 38-51.
    • (2003) Brain Pathol. , vol.13 , pp. 38-51
    • Columba-Cabezas, S.1    Serafini, B.2    Ambrosini, E.3    Aloisi, F.4
  • 179
    • 33751557620 scopus 로고    scopus 로고
    • CXCL12 limits inflammation by localizing mononuclear infiltrates to the perivascular space during experimental autoimmune encephalomyelitis
    • McCandless, E. E., Wang, Q., Woerner, B. M., Harper, J. M., Klein, R. S. (2006) CXCL12 limits inflammation by localizing mononuclear infiltrates to the perivascular space during experimental autoimmune encephalomyelitis. J. Immunol. 177, 8053-8064.
    • (2006) J. Immunol. , vol.177 , pp. 8053-8064
    • McCandless, E.E.1    Wang, Q.2    Woerner, B.M.3    Harper, J.M.4    Klein, R.S.5
  • 181
    • 17044372405 scopus 로고    scopus 로고
    • CCL2 and CCL5 mediate leukocyte adhesion in experimental autoimmune encephalomyelitis-an intravital microscopy study
    • Dos Santos, A. C., Barsante, M. M., Arantes, R. M., Bernard, C. C., Teixeira, M. M., Carvalho-Tavares, J. (2005) CCL2 and CCL5 mediate leukocyte adhesion in experimental autoimmune encephalomyelitis-an intravital microscopy study. J. Neuroimmunol. 162, 122-129.
    • (2005) J. Neuroimmunol. , vol.162 , pp. 122-129
    • dos Santos, A.C.1    Barsante, M.M.2    Arantes, R.M.3    Bernard, C.C.4    Teixeira, M.M.5    Carvalho-Tavares, J.6
  • 183
    • 3843126572 scopus 로고    scopus 로고
    • Chemokine CCL2 and chemokine receptor CCR2 in early active multiple sclerosis
    • Sørensen, T. L., Ransohoff, R. M., Strieter, R. M., Sellebjerg, F. (2004) Chemokine CCL2 and chemokine receptor CCR2 in early active multiple sclerosis. Eur. J. Neurol. 11, 445-449.
    • (2004) Eur. J. Neurol. , vol.11 , pp. 445-449
    • Sørensen, T.L.1    Ransohoff, R.M.2    Strieter, R.M.3    Sellebjerg, F.4
  • 184
    • 0036041995 scopus 로고    scopus 로고
    • T-cells in the cerebrospinal fluid express a similar repertoire of inflammatory chemokine receptors in the absence or presence of CNS inflammation: Implications for CNS trafficking
    • Kivisäkk, P., Trebst, C., Liu, Z., Tucky, B. H., Sørensen, T. L., Rudick, R. A., Mack, M., Ransohoff, R. M. (2002) T-cells in the cerebrospinal fluid express a similar repertoire of inflammatory chemokine receptors in the absence or presence of CNS inflammation: implications for CNS trafficking. Clin. Exp. Immunol. 129, 510-518.
    • (2002) Clin. Exp. Immunol. , vol.129 , pp. 510-518
    • Kivisäkk, P.1    Trebst, C.2    Liu, Z.3    Tucky, B.H.4    Sørensen, T.L.5    Rudick, R.A.6    Mack, M.7    Ransohoff, R.M.8
  • 189
  • 190
    • 3242683494 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate receptor agonists attenuate relapsing-remitting experimental autoimmune encephalitis in SJL mice
    • Webb, M., Tham, C. S., Lin, F. F., Lariosa-Willingham, K., Yu, N., Hale, J., Mandala, S., Chun, J., Rao, T. S. (2004) Sphingosine 1-phosphate receptor agonists attenuate relapsing-remitting experimental autoimmune encephalitis in SJL mice. J. Neuroimmunol. 153, 108-121.
    • (2004) J. Neuroimmunol. , vol.153 , pp. 108-121
    • Webb, M.1    Tham, C.S.2    Lin, F.F.3    Lariosa-Willingham, K.4    Yu, N.5    Hale, J.6    Mandala, S.7    Chun, J.8    Rao, T.S.9
  • 191
    • 14044258490 scopus 로고    scopus 로고
    • Cutting edge: Regulation of T cell trafficking and primary immune responses by sphingosine 1-phosphate receptor 1
    • Chi, H., Flavell, R. A. (2005) Cutting edge: regulation of T cell trafficking and primary immune responses by sphingosine 1-phosphate receptor 1. J. Immunol. 174, 2485-2488.
    • (2005) J. Immunol. , vol.174 , pp. 2485-2488
    • Chi, H.1    Flavell, R.A.2
  • 192
    • 33645283403 scopus 로고    scopus 로고
    • FTY720, sphingosine 1-phosphate receptor modulator, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration
    • Kataoka, H., Sugahara, K., Shimano, K., Teshima, K., Koyama, M., Fukunari, A., Chiba, K. (2005) FTY720, sphingosine 1-phosphate receptor modulator, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration. Cell. Mol. Immunol. 2, 439-448.
    • (2005) Cell. Mol. Immunol. , vol.2 , pp. 439-448
    • Kataoka, H.1    Sugahara, K.2    Shimano, K.3    Teshima, K.4    Koyama, M.5    Fukunari, A.6    Chiba, K.7
  • 193
    • 53049085954 scopus 로고    scopus 로고
    • Central nervous systemdirected effects of FTY720 (fingolimod)
    • Miron, V. E., Schubart, A., Antel, J. P. (2008) Central nervous systemdirected effects of FTY720 (fingolimod). J. Neurol. Sci. 274, 13-17.
    • (2008) J. Neurol. Sci. , vol.274 , pp. 13-17
    • Miron, V.E.1    Schubart, A.2    Antel, J.P.3
  • 194
    • 61649121740 scopus 로고    scopus 로고
    • FTY720 rescue therapy in the dark agouti rat model of experimental autoimmune encephalomyelitis: Expression of central nervous system genes and reversal of blood-brain-barrier damage
    • Foster, C. A., Mechtcheriakova, D., Storch, M. K., Balatoni, B., Howard, L. M., Bornancin, F., Wlachos, A., Sobanov, J., Kinnunen, A., Baumruker, T. (2009) FTY720 rescue therapy in the dark agouti rat model of experimental autoimmune encephalomyelitis: expression of central nervous system genes and reversal of blood-brain-barrier damage. Brain Pathol. 19, 254-266.
    • (2009) Brain Pathol. , vol.19 , pp. 254-266
    • Foster, C.A.1    Mechtcheriakova, D.2    Storch, M.K.3    Balatoni, B.4    Howard, L.M.5    Bornancin, F.6    Wlachos, A.7    Sobanov, J.8    Kinnunen, A.9    Baumruker, T.10
  • 195
    • 77951073508 scopus 로고    scopus 로고
    • Mechanism of action of oral fingolimod (FTY720) in multiple sclerosis
    • Chun, J., Hartung, H. P. (2010) Mechanism of action of oral fingolimod (FTY720) in multiple sclerosis. Clin. Neuropharmacol. 33, 91-101.
    • (2010) Clin. Neuropharmacol. , vol.33 , pp. 91-101
    • Chun, J.1    Hartung, H.P.2
  • 198
    • 70149102687 scopus 로고    scopus 로고
    • Reemergence of PML in natalizumab-treated patients-new cases, same concerns
    • Major, E. O. (2009) Reemergence of PML in natalizumab-treated patients-new cases, same concerns. N. Engl. J. Med. 361, 1041-1043.
    • (2009) N. Engl. J. Med. , vol.361 , pp. 1041-1043
    • Major, E.O.1
  • 200
    • 27744500993 scopus 로고    scopus 로고
    • Natalizumab and PML
    • Ransohoff, R. M. (2005) Natalizumab and PML. Nat. Neurosci. 8, 1275.
    • (2005) Nat. Neurosci. , vol.8 , pp. 1275
    • Ransohoff, R.M.1
  • 202
    • 78650725673 scopus 로고    scopus 로고
    • Natalizumab induces a rapid improvement of disability status and ambulation after failure of previous therapy in relapsing-remitting multiple sclerosis
    • Epub ahead of print
    • Belachew, S., Phan-Ba, R., Bartholome, E., Delvaux, V., Hansen, I., Calay, P., Hafsi, K. E., Moonen, G., Tshibanda, L., Vokaer, M. (2010) Natalizumab induces a rapid improvement of disability status and ambulation after failure of previous therapy in relapsing-remitting multiple sclerosis. Eur. J. Neurol., Epub ahead of print.
    • (2010) Eur. J. Neurol.
    • Belachew, S.1    Phan-Ba, R.2    Bartholome, E.3    Delvaux, V.4    Hansen, I.5    Calay, P.6    Hafsi, K.E.7    Moonen, G.8    Tshibanda, L.9    Vokaer, M.10
  • 206
    • 0025015655 scopus 로고
    • Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages
    • Huitinga, I., van Rooijen, N., de Groot, C. J., Uitdehaag, B. M., Dijkstra, C. D. (1990) Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages. J. Exp. Med. 172, 1025-1033.
    • (1990) J. Exp. Med. , vol.172 , pp. 1025-1033
    • Huitinga, I.1    van Rooijen, N.2    de Groot, C.J.3    Uitdehaag, B.M.4    Dijkstra, C.D.5
  • 207
    • 0028243075 scopus 로고
    • Monocyte adhesion to endothelium in simian immunodeficiency virus-induced AIDS encephalitis is mediated by vascular cell adhesion molecule-1/α 4 β 1 integrin interactions
    • Sasseville, V. G., Newman, W., Brodie, S. J., Hesterberg, P., Pauley, D., Ringler, D. J. (1994) Monocyte adhesion to endothelium in simian immunodeficiency virus-induced AIDS encephalitis is mediated by vascular cell adhesion molecule-1/α 4 β 1 integrin interactions. Am. J. Pathol. 144, 27-40.
    • (1994) Am. J. Pathol. , vol.144 , pp. 27-40
    • Sasseville, V.G.1    Newman, W.2    Brodie, S.J.3    Hesterberg, P.4    Pauley, D.5    Ringler, D.J.6
  • 208
    • 4444290680 scopus 로고    scopus 로고
    • Macrophage brain infiltration in experimental autoimmune encephalomyelitis is not completely compromised by suppressed T-cell invasion: In vivo magnetic resonance imaging illustration in effective anti-VLA-4 antibody treatment
    • Deloire, M. S., Touil, T., Brochet, B., Dousset, V., Caille, J. M., Petry, K. G. (2004) Macrophage brain infiltration in experimental autoimmune encephalomyelitis is not completely compromised by suppressed T-cell invasion: in vivo magnetic resonance imaging illustration in effective anti-VLA-4 antibody treatment. Mult. Scler. 10, 540-548.
    • (2004) Mult. Scler. , vol.10 , pp. 540-548
    • Deloire, M.S.1    Touil, T.2    Brochet, B.3    Dousset, V.4    Caille, J.M.5    Petry, K.G.6
  • 212
    • 0035849120 scopus 로고    scopus 로고
    • Aging and the public health effects of dementia
    • Kawas, C. H., Brookmeyer, R. (2001) Aging and the public health effects of dementia. N. Engl. J. Med. 344, 1160-1161.
    • (2001) N. Engl. J. Med. , vol.344 , pp. 1160-1161
    • Kawas, C.H.1    Brookmeyer, R.2
  • 214
    • 37049048544 scopus 로고
    • Paired helical filaments in electron microscopy of Alzheimer's disease
    • Kidd, M. (1963) Paired helical filaments in electron microscopy of Alzheimer's disease. Nature 197, 192-193.
    • (1963) Nature , vol.197 , pp. 192-193
    • Kidd, M.1
  • 215
    • 0024434236 scopus 로고
    • Ultrastructural studies of the cells forming amyloid fibers in classical plaques
    • Wisniewski, H. M., Wegiel, J., Wang, K. C., Kujawa, M., Lach, B. (1989) Ultrastructural studies of the cells forming amyloid fibers in classical plaques. Can. J. Neurol. Sci. 16, 535-542.
    • (1989) Can. J. Neurol. Sci. , vol.16 , pp. 535-542
    • Wisniewski, H.M.1    Wegiel, J.2    Wang, K.C.3    Kujawa, M.4    Lach, B.5
  • 216
    • 49449093147 scopus 로고    scopus 로고
    • The inflammatory response in Alzheimer's disease
    • Rogers, J. (2008) The inflammatory response in Alzheimer's disease. J. Periodontol. 79, 1535-1543.
    • (2008) J. Periodontol. , vol.79 , pp. 1535-1543
    • Rogers, J.1
  • 217
    • 1542283611 scopus 로고    scopus 로고
    • Neuroinflammatory perspectives on the two faces of Alzheimer's disease
    • Eikelenboom, P., van Gool, W. A. (2004) Neuroinflammatory perspectives on the two faces of Alzheimer's disease. J. Neural Transm. 111, 281-294.
    • (2004) J. Neural Transm. , vol.111 , pp. 281-294
    • Eikelenboom, P.1    van Gool, W.A.2
  • 219
    • 67349142021 scopus 로고    scopus 로고
    • Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease
    • Bell, R. D., Zlokovic, B. V. (2009) Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease. Acta Neuropathol. 118, 103-113.
    • (2009) Acta Neuropathol. , vol.118 , pp. 103-113
    • Bell, R.D.1    Zlokovic, B.V.2
  • 220
    • 72849106266 scopus 로고    scopus 로고
    • A leaky blood-brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer's disease brain
    • Ryu, J. K., McLarnon, J. G. (2009) A leaky blood-brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer's disease brain. J. Cell. Mol. Med. 13, 2911-2925.
    • (2009) J. Cell. Mol. Med. , vol.13 , pp. 2911-2925
    • Ryu, J.K.1    McLarnon, J.G.2
  • 221
    • 0031179444 scopus 로고    scopus 로고
    • In vivo vascular damage, leukocyte activation and inflammatory response induced by β-amyloid
    • Thomas, T., Sutton, E. T., Bryant, M. W., Rhodin, J. A. (1997) In vivo vascular damage, leukocyte activation and inflammatory response induced by β-amyloid. J. Submicrosc. Cytol. Pathol. 29, 293-304.
    • (1997) J. Submicrosc. Cytol. Pathol. , vol.29 , pp. 293-304
    • Thomas, T.1    Sutton, E.T.2    Bryant, M.W.3    Rhodin, J.A.4
  • 222
    • 7644219821 scopus 로고    scopus 로고
    • Amyloid angiopathy-related vascular cognitive impairment
    • Greenberg, S. M., Gurol, M. E., Rosand, J., Smith, E. E. (2004) Amyloid angiopathy-related vascular cognitive impairment. Stroke 35, 2616-2619.
    • (2004) Stroke , vol.35 , pp. 2616-2619
    • Greenberg, S.M.1    Gurol, M.E.2    Rosand, J.3    Smith, E.E.4
  • 223
    • 0021256895 scopus 로고
    • Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
    • Glenner, G. G., Wong, C. W. (1984) Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem. Biophys. Res. Commun. 120, 885-890.
    • (1984) Biochem. Biophys. Res. Commun. , vol.120 , pp. 885-890
    • Glenner, G.G.1    Wong, C.W.2
  • 224
    • 0036323445 scopus 로고    scopus 로고
    • Alzheimer disease and cerebrovascular pathology: An update
    • Jellinger, K. A. (2002) Alzheimer disease and cerebrovascular pathology: an update. J. Neural Transm. 109, 813-836.
    • (2002) J. Neural Transm. , vol.109 , pp. 813-836
    • Jellinger, K.A.1
  • 225
    • 0023254674 scopus 로고
    • Cerebral amyloid angiopathy. A critical review
    • Vinters, H. V. (1987) Cerebral amyloid angiopathy. A critical review. Stroke 18, 311-324.
    • (1987) Stroke , vol.18 , pp. 311-324
    • Vinters, H.V.1
  • 226
    • 0030452414 scopus 로고    scopus 로고
    • Cerebral vessels in ageing and Alzheimer's disease
    • Kalaria, R. N. (1996) Cerebral vessels in ageing and Alzheimer's disease. Pharmacol. Ther. 72, 193-214.
    • (1996) Pharmacol. Ther. , vol.72 , pp. 193-214
    • Kalaria, R.N.1
  • 227
    • 46749099351 scopus 로고    scopus 로고
    • New therapeutic targets in the neurovascular pathway in Alzheimer's disease
    • Zlokovic, B. V. (2008) New therapeutic targets in the neurovascular pathway in Alzheimer's disease. Neurotherapeutics 5, 409-414.
    • (2008) Neurotherapeutics , vol.5 , pp. 409-414
    • Zlokovic, B.V.1
  • 228
    • 77955060978 scopus 로고    scopus 로고
    • Membrane biophysics and mechanics in Alzheimer's disease
    • Yang, X., Askarova, S., Lee, J. C. (2010) Membrane biophysics and mechanics in Alzheimer's disease. Mol. Neurobiol. 41, 138-148.
    • (2010) Mol. Neurobiol. , vol.41 , pp. 138-148
    • Yang, X.1    Askarova, S.2    Lee, J.C.3
  • 230
    • 0032487625 scopus 로고    scopus 로고
    • Alzheimer's β-amyloid peptides induce inflammatory cascade in human vascular cells: The roles of cytokines and CD40
    • Suo, Z., Tan, J., Placzek, A., Crawford, F., Fang, C., Mullan, M. (1998) Alzheimer's β-amyloid peptides induce inflammatory cascade in human vascular cells: the roles of cytokines and CD40. Brain Res. 807, 110-117.
    • (1998) Brain Res. , vol.807 , pp. 110-117
    • Suo, Z.1    Tan, J.2    Placzek, A.3    Crawford, F.4    Fang, C.5    Mullan, M.6
  • 231
    • 0242636129 scopus 로고    scopus 로고
    • In vivo cerebrovascular actions of amyloid β-peptides and the protective effect of conjugated estrogens
    • Rhodin, J. A., Thomas, T. N., Clark, L., Garces, A., Bryant, M. (2003) In vivo cerebrovascular actions of amyloid β-peptides and the protective effect of conjugated estrogens. J. Alzheimers Dis. 5, 275-286.
    • (2003) J. Alzheimers Dis. , vol.5 , pp. 275-286
    • Rhodin, J.A.1    Thomas, T.N.2    Clark, L.3    Garces, A.4    Bryant, M.5
  • 232
    • 0030827642 scopus 로고    scopus 로고
    • Association of vascular amyloid β and cells of the mononuclear phagocyte system in hereditary cerebral hemorrhage with amyloidosis (Dutch) and Alzheimer disease
    • Maat-Schieman, M. L., van Duinen, S. G., Rozemuller, A. J., Haan, J., Roos, R. A. (1997) Association of vascular amyloid β and cells of the mononuclear phagocyte system in hereditary cerebral hemorrhage with amyloidosis (Dutch) and Alzheimer disease. J. Neuropathol. Exp. Neurol. 56, 273-284.
    • (1997) J. Neuropathol. Exp. Neurol. , vol.56 , pp. 273-284
    • Maat-Schieman, M.L.1    van Duinen, S.G.2    Rozemuller, A.J.3    Haan, J.4    Roos, R.A.5
  • 233
    • 0030691019 scopus 로고    scopus 로고
    • Activated microglial cells are colocalized with perivascular deposits of amyloid-β protein in Alzheimer's disease brain
    • Uchihara, T., Akiyama, H., Kondo, H., Ikeda, K. (1997) Activated microglial cells are colocalized with perivascular deposits of amyloid-β protein in Alzheimer's disease brain. Stroke 28, 1948-1950.
    • (1997) Stroke , vol.28 , pp. 1948-1950
    • Uchihara, T.1    Akiyama, H.2    Kondo, H.3    Ikeda, K.4
  • 235
    • 37349003744 scopus 로고    scopus 로고
    • Soluble aggregates of the amyloid-β protein activate endothelial monolayers for adhesion and subsequent transmigration of monocyte cells
    • Gonzalez-Velasquez, F. J., Moss, M. A. (2008) Soluble aggregates of the amyloid-β protein activate endothelial monolayers for adhesion and subsequent transmigration of monocyte cells. J. Neurochem. 104, 500-513.
    • (2008) J. Neurochem. , vol.104 , pp. 500-513
    • Gonzalez-Velasquez, F.J.1    Moss, M.A.2
  • 236
    • 32344440522 scopus 로고    scopus 로고
    • Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease
    • Simard, A. R., Soulet, D., Gowing, G., Julien, J. P., Rivest, S. (2006) Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease. Neuron 49, 489-502.
    • (2006) Neuron , vol.49 , pp. 489-502
    • Simard, A.R.1    Soulet, D.2    Gowing, G.3    Julien, J.P.4    Rivest, S.5
  • 237
    • 0023772808 scopus 로고
    • Presence of T-cytotoxic suppressor and leucocyte common antigen positive cells in Alzheimer's disease brain tissue
    • Itagaki, S., McGeer, P. L., Akiyama, H. (1988) Presence of T-cytotoxic suppressor and leucocyte common antigen positive cells in Alzheimer's disease brain tissue. Neurosci. Lett. 91, 259-264.
    • (1988) Neurosci. Lett. , vol.91 , pp. 259-264
    • Itagaki, S.1    McGeer, P.L.2    Akiyama, H.3
  • 240
    • 0024157709 scopus 로고
    • Expression of immune system-associated antigens by cells of the human central nervous system: Relationship to the pathology of Alzheimer's disease
    • Rogers, J., Luber-Narod, J., Styren, S. D., Civin, W. H. (1988) Expression of immune system-associated antigens by cells of the human central nervous system: relationship to the pathology of Alzheimer's disease. Neurobiol. Aging 9, 339-349.
    • (1988) Neurobiol. Aging , vol.9 , pp. 339-349
    • Rogers, J.1    Luber-Narod, J.2    Styren, S.D.3    Civin, W.H.4
  • 244
    • 33847128514 scopus 로고    scopus 로고
    • Peripheral T cells overexpress MIP-1α to enhance its transendothelial migration in Alzheimer's disease
    • Man, S. M., Ma, Y. R., Shang, D. S., Zhao, W. D., Li, B., Guo, D. W., Fang, W. G., Zhu, L., Chen, Y. H. (2007) Peripheral T cells overexpress MIP-1α to enhance its transendothelial migration in Alzheimer's disease. Neurobiol. Aging 28, 485-496.
    • (2007) Neurobiol. Aging , vol.28 , pp. 485-496
    • Man, S.M.1    Ma, Y.R.2    Shang, D.S.3    Zhao, W.D.4    Li, B.5    Guo, D.W.6    Fang, W.G.7    Zhu, L.8    Chen, Y.H.9
  • 245
    • 66949169952 scopus 로고    scopus 로고
    • Amyloid β interaction with receptor for advanced glycation end products up-regulates brain endothelial CCR5 expression and promotes T cells crossing the blood-brain barrier
    • Li, M., Shang, D. S., Zhao, W. D., Tian, L., Li, B., Fang, W. G., Zhu, L., Man, S. M., Chen, Y. H. (2009) Amyloid β interaction with receptor for advanced glycation end products up-regulates brain endothelial CCR5 expression and promotes T cells crossing the blood-brain barrier. J. Immunol. 182, 5778-5788.
    • (2009) J. Immunol. , vol.182 , pp. 5778-5788
    • Li, M.1    Shang, D.S.2    Zhao, W.D.3    Tian, L.4    Li, B.5    Fang, W.G.6    Zhu, L.7    Man, S.M.8    Chen, Y.H.9
  • 246
    • 71349085295 scopus 로고    scopus 로고
    • Peripheral T cells derived from Alzheimer's disease patients overexpress CXCR2 contributing to its transendothelial migration, which is microglial TNF-α-dependent
    • Liu, Y. J., Guo, D. W., Tian, L., Shang, D. S., Zhao, W. D., Li, B., Fang, W. G., Zhu, L., Chen, Y. H. (2010) Peripheral T cells derived from Alzheimer's disease patients overexpress CXCR2 contributing to its transendothelial migration, which is microglial TNF-α-dependent. Neurobiol. Aging 31, 175-188.
    • (2010) Neurobiol. Aging , vol.31 , pp. 175-188
    • Liu, Y.J.1    Guo, D.W.2    Tian, L.3    Shang, D.S.4    Zhao, W.D.5    Li, B.6    Fang, W.G.7    Zhu, L.8    Chen, Y.H.9
  • 247
    • 2142649221 scopus 로고    scopus 로고
    • Biomarkers of endothelial dysfunction and risk of type 2 diabetes mellitus
    • Meigs, J. B., Hu, F. B., Rifai, N., Manson, J. E. (2004) Biomarkers of endothelial dysfunction and risk of type 2 diabetes mellitus. JAMA 291, 1978-1986.
    • (2004) JAMA , vol.291 , pp. 1978-1986
    • Meigs, J.B.1    Hu, F.B.2    Rifai, N.3    Manson, J.E.4
  • 248
    • 77955047267 scopus 로고    scopus 로고
    • A summary risk score for the prediction of Alzheimer disease in elderly persons
    • Reitz, C., Tang, M. X., Schupf, N., Manly, J. J., Mayeux, R., Luchsinger, J. A. (2010) A summary risk score for the prediction of Alzheimer disease in elderly persons. Arch. Neurol. 67, 835-841.
    • (2010) Arch. Neurol. , vol.67 , pp. 835-841
    • Reitz, C.1    Tang, M.X.2    Schupf, N.3    Manly, J.J.4    Mayeux, R.5    Luchsinger, J.A.6
  • 249
    • 68949089312 scopus 로고    scopus 로고
    • Alzheimer's disease is type 3 diabetes-evidence reviewed
    • De la Monte, S. M., Wands, J. R. (2008) Alzheimer's disease is type 3 diabetes-evidence reviewed. J. Diabetes Sci. Technol. 2, 1101-1113.
    • (2008) J. Diabetes Sci. Technol. , vol.2 , pp. 1101-1113
    • de la Monte, S.M.1    Wands, J.R.2
  • 250
    • 48349091599 scopus 로고    scopus 로고
    • Markers of endothelial dysfunction in older subjects with late onset Alzheimer's disease or vascular dementia
    • Zuliani, G., Cavalieri, M., Galvani, M., Passaro, A., Munari, M. R., Bosi, C., Zurlo, A., Fellin, R. (2008) Markers of endothelial dysfunction in older subjects with late onset Alzheimer's disease or vascular dementia. J. Neurol. Sci. 272, 164-170.
    • (2008) J. Neurol. Sci. , vol.272 , pp. 164-170
    • Zuliani, G.1    Cavalieri, M.2    Galvani, M.3    Passaro, A.4    Munari, M.R.5    Bosi, C.6    Zurlo, A.7    Fellin, R.8
  • 253
    • 0028276177 scopus 로고
    • Cellular and substrate adhesion molecules (integrins) and their ligands in cerebral amyloid plaques in Alzheimer's disease
    • Eikelenboom, P., Zhan, S. S., Kamphorst, W., van der Valk, P., Rozemuller, J. M. (1994) Cellular and substrate adhesion molecules (integrins) and their ligands in cerebral amyloid plaques in Alzheimer's disease. Virchows Arch. 424, 421-427.
    • (1994) Virchows Arch. , vol.424 , pp. 421-427
    • Eikelenboom, P.1    Zhan, S.S.2    Kamphorst, W.3    van der Valk, P.4    Rozemuller, J.M.5
  • 254
    • 15844373497 scopus 로고    scopus 로고
    • Differential expression of intercellular adhesion molecule-1 (ICAM-1) in the A β-containing lesions in brains of patients with dementia of the Alzheimer type
    • Verbeek, M. M., Otte-Holler, I., Wesseling, P., Ruiter, D. J., de Waal, R. M. (1996) Differential expression of intercellular adhesion molecule-1 (ICAM-1) in the A β-containing lesions in brains of patients with dementia of the Alzheimer type. Acta Neuropathol. 91, 608-615.
    • (1996) Acta Neuropathol. , vol.91 , pp. 608-615
    • Verbeek, M.M.1    Otte-Holler, I.2    Wesseling, P.3    Ruiter, D.J.4    de Waal, R.M.5
  • 255
    • 0037162769 scopus 로고    scopus 로고
    • β-Amyloid-associated expression of intercellular adhesion molecule-1 in brain cortical tissue of transgenic Tg2576 mice
    • Apelt, J., Lessig, J., Schliebs, R. (2002) β-Amyloid-associated expression of intercellular adhesion molecule-1 in brain cortical tissue of transgenic Tg2576 mice. Neurosci. Lett. 329, 111-115.
    • (2002) Neurosci. Lett. , vol.329 , pp. 111-115
    • Apelt, J.1    Lessig, J.2    Schliebs, R.3
  • 257
    • 0027219569 scopus 로고
    • Expression of intercellular adhesion molecule (ICAM)-1 by a subset of astrocytes in Alzheimer disease and some other degenerative neurological disorders
    • Akiyama, H., Kawamata, T., Yamada, T., Tooyama, I., Ishii, T., McGeer, P. L. (1993) Expression of intercellular adhesion molecule (ICAM)-1 by a subset of astrocytes in Alzheimer disease and some other degenerative neurological disorders. Acta Neuropathol. 85, 628-634.
    • (1993) Acta Neuropathol. , vol.85 , pp. 628-634
    • Akiyama, H.1    Kawamata, T.2    Yamada, T.3    Tooyama, I.4    Ishii, T.5    McGeer, P.L.6
  • 258
    • 0035695987 scopus 로고    scopus 로고
    • Gene expression profiling of amyloid β peptide-stimulated human post-mortem brain microglia
    • Walker, D. G., Lue, L. F., Beach, T. G. (2001) Gene expression profiling of amyloid β peptide-stimulated human post-mortem brain microglia. Neurobiol. Aging 22, 957-966.
    • (2001) Neurobiol. Aging , vol.22 , pp. 957-966
    • Walker, D.G.1    Lue, L.F.2    Beach, T.G.3
  • 260
    • 33947205974 scopus 로고    scopus 로고
    • Soluble adhesion molecules and angiotensin-converting enzyme in dementia
    • Nielsen, H. M., Londos, E., Minthon, L., Janciauskiene, S. M. (2007) Soluble adhesion molecules and angiotensin-converting enzyme in dementia. Neurobiol. Dis. 26, 27-35.
    • (2007) Neurobiol. Dis. , vol.26 , pp. 27-35
    • Nielsen, H.M.1    Londos, E.2    Minthon, L.3    Janciauskiene, S.M.4
  • 263
  • 264
    • 0041885330 scopus 로고    scopus 로고
    • Circulating vascular cell adhesion molecules VCAM-1, ICAM-1, and E-selectin in dependence on aging
    • Richter, V., Rassoul, F., Purschwitz, K., Hentschel, B., Reuter, W., Kuntze, T. (2003) Circulating vascular cell adhesion molecules VCAM-1, ICAM-1, and E-selectin in dependence on aging. Gerontology 49, 293-300.
    • (2003) Gerontology , vol.49 , pp. 293-300
    • Richter, V.1    Rassoul, F.2    Purschwitz, K.3    Hentschel, B.4    Reuter, W.5    Kuntze, T.6
  • 265
    • 41349111452 scopus 로고    scopus 로고
    • Parkinson's disease-Part 1: Pathophysiology, symptoms, burden, diagnosis, and assessment
    • Weintraub, D., Comella, C. L., Horn, S. (2008) Parkinson's disease-Part 1: pathophysiology, symptoms, burden, diagnosis, and assessment. Am. J. Manag. Care 14, S40-S48.
    • (2008) Am. J. Manag. Care , vol.14
    • Weintraub, D.1    Comella, C.L.2    Horn, S.3
  • 266
    • 34548822734 scopus 로고    scopus 로고
    • The role of anti-inflammatory agents in Parkinson's disease
    • McGeer, E. G., McGeer, P. L. (2007) The role of anti-inflammatory agents in Parkinson's disease. CNS Drugs 21, 789-797.
    • (2007) CNS Drugs , vol.21 , pp. 789-797
    • McGeer, E.G.1    McGeer, P.L.2
  • 267
    • 44149103168 scopus 로고    scopus 로고
    • Neuroinflammation and peripheral immune infiltration in Parkinson's disease: An autoimmune hypothesis
    • Monahan, A. J., Warren, M., Carvey, P. M. (2008) Neuroinflammation and peripheral immune infiltration in Parkinson's disease: an autoimmune hypothesis. Cell Transplant. 17, 363-372.
    • (2008) Cell Transplant. , vol.17 , pp. 363-372
    • Monahan, A.J.1    Warren, M.2    Carvey, P.M.3
  • 268
    • 0344076112 scopus 로고    scopus 로고
    • MHC class II positive microglia and lymphocytic infiltration are present in the substantia nigra and striatum in mouse model of Parkinson's disease
    • Kurkowska-Jastrzebska, I., Wronska, A., Kohutnicka, M., Czlonkowski, A., Czlonkowska, A. (1999) MHC class II positive microglia and lymphocytic infiltration are present in the substantia nigra and striatum in mouse model of Parkinson's disease. Acta Neurobiol. Exp. (Warsz.) 59, 1-8.
    • (1999) Acta Neurobiol. Exp. (Warsz.) , vol.59 , pp. 1-8
    • Kurkowska-Jastrzebska, I.1    Wronska, A.2    Kohutnicka, M.3    Czlonkowski, A.4    Czlonkowska, A.5
  • 269
    • 30444443297 scopus 로고    scopus 로고
    • Role of ICAM-1 in persisting inflammation in Parkinson disease and MPTP monkeys
    • Miklossy, J., Doudet, D. D., Schwab, C., Yu, S., McGeer, E. G., McGeer, P. L. (2006) Role of ICAM-1 in persisting inflammation in Parkinson disease and MPTP monkeys. Exp. Neurol. 197, 275-283.
    • (2006) Exp. Neurol. , vol.197 , pp. 275-283
    • Miklossy, J.1    Doudet, D.D.2    Schwab, C.3    Yu, S.4    McGeer, E.G.5    McGeer, P.L.6
  • 270
    • 0034788215 scopus 로고    scopus 로고
    • Increase in peripheral CD4 bright+ CD8 dull+ T cells in Parkinson disease
    • Hisanaga, K., Asagi, M., Itoyama, Y., Iwasaki, Y. (2001) Increase in peripheral CD4 bright+ CD8 dull+ T cells in Parkinson disease. Arch. Neurol. 58, 1580-1583.
    • (2001) Arch. Neurol. , vol.58 , pp. 1580-1583
    • Hisanaga, K.1    Asagi, M.2    Itoyama, Y.3    Iwasaki, Y.4
  • 271
    • 0027980729 scopus 로고
    • Parkinson's disease and immunological abnormalities: Increase of HLA-DR expression on monocytes in cerebrospinal fluid and of CD45RO+ T cells in peripheral blood
    • Fiszer, U., Mix, E., Fredrikson, S., Kostulas, V., Link, H. (1994) Parkinson's disease and immunological abnormalities: increase of HLA-DR expression on monocytes in cerebrospinal fluid and of CD45RO+ T cells in peripheral blood. Acta Neurol. Scand. 90, 160-166.
    • (1994) Acta Neurol. Scand. , vol.90 , pp. 160-166
    • Fiszer, U.1    Mix, E.2    Fredrikson, S.3    Kostulas, V.4    Link, H.5
  • 272
    • 51349127386 scopus 로고    scopus 로고
    • Differential neutrophil infiltration contributes to regional differences in brain inflammation in the substantia nigra pars compacta and cortex
    • Ji, K. A., Eu, M. Y., Kang, S. H., Gwag, B. J., Jou, I., Joe, E. H. (2008) Differential neutrophil infiltration contributes to regional differences in brain inflammation in the substantia nigra pars compacta and cortex. Glia 56, 1039-1047.
    • (2008) Glia , vol.56 , pp. 1039-1047
    • Ji, K.A.1    Eu, M.Y.2    Kang, S.H.3    Gwag, B.J.4    Jou, I.5    Joe, E.H.6
  • 275
    • 36549071601 scopus 로고    scopus 로고
    • Innate and adaptive immunity during epileptogenesis and spontaneous seizures: Evidence from experimental models and human temporal lobe epilepsy
    • Ravizza, T., Gagliardi, B., Noe, F., Boer, K., Aronica, E., Vezzani, A. (2008) Innate and adaptive immunity during epileptogenesis and spontaneous seizures: evidence from experimental models and human temporal lobe epilepsy. Neurobiol. Dis. 29, 142-160.
    • (2008) Neurobiol. Dis. , vol.29 , pp. 142-160
    • Ravizza, T.1    Gagliardi, B.2    Noe, F.3    Boer, K.4    Aronica, E.5    Vezzani, A.6
  • 277
    • 0029088930 scopus 로고
    • Adhesion molecule expression on murine cerebral endothelium following the injection of a proinflammagen or during acute neuronal degeneration
    • Bell, M. D., Perry, V. H. (1995) Adhesion molecule expression on murine cerebral endothelium following the injection of a proinflammagen or during acute neuronal degeneration. J. Neurocytol. 24, 695-710.
    • (1995) J. Neurocytol. , vol.24 , pp. 695-710
    • Bell, M.D.1    Perry, V.H.2
  • 278
    • 34247176722 scopus 로고    scopus 로고
    • Expression of adhesion factors induced by epileptiform activity in the endothelium of the isolated guinea pig brain in vitro
    • Librizzi, L., Regondi, M. C., Pastori, C., Frigerio, S., Frassoni, C., de Curtis, M. (2007) Expression of adhesion factors induced by epileptiform activity in the endothelium of the isolated guinea pig brain in vitro. Epilepsia 48, 743-751.
    • (2007) Epilepsia , vol.48 , pp. 743-751
    • Librizzi, L.1    Regondi, M.C.2    Pastori, C.3    Frigerio, S.4    Frassoni, C.5    de Curtis, M.6
  • 279
    • 58149352396 scopus 로고    scopus 로고
    • Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis
    • Kim, J. V., Kang, S. S., Dustin, M. L., McGavern, D. B. (2009) Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis. Nature 457, 191-195.
    • (2009) Nature , vol.457 , pp. 191-195
    • Kim, J.V.1    Kang, S.S.2    Dustin, M.L.3    McGavern, D.B.4
  • 280
    • 77956875172 scopus 로고    scopus 로고
    • Treatment of refractory epilepsy with natalizumab in a patient with multiple sclerosis. Case report
    • Sotgiu, S., Murrighile, M. R., Constantin, G. (2010) Treatment of refractory epilepsy with natalizumab in a patient with multiple sclerosis. Case report. BMC Neurol. 10, 84.
    • (2010) BMC Neurol. , vol.10 , pp. 84
    • Sotgiu, S.1    Murrighile, M.R.2    Constantin, G.3
  • 281
    • 69949145443 scopus 로고    scopus 로고
    • CCR3, CCR2A and macrophage inflammatory protein (MIP)-1α, monocyte chemotactic protein-1 (MCP-1) in the mouse hippocampus during and after pilocarpine-induced status epilepticus (PISE)
    • Xu, J. H., Long, L., Tang, Y. C., Zhang, J. T., Hut, H. T., Tang, F. R. (2009) CCR3, CCR2A and macrophage inflammatory protein (MIP)-1α, monocyte chemotactic protein-1 (MCP-1) in the mouse hippocampus during and after pilocarpine-induced status epilepticus (PISE). Neuropathol. Appl. Neurobiol. 35, 496-514.
    • (2009) Neuropathol. Appl. Neurobiol. , vol.35 , pp. 496-514
    • Xu, J.H.1    Long, L.2    Tang, Y.C.3    Zhang, J.T.4    Hut, H.T.5    Tang, F.R.6
  • 282
    • 36049000222 scopus 로고    scopus 로고
    • Characterization of monocyte chemoattractant protein-1 expression following a kainate model of status epilepticus
    • Manley, N. C., Bertrand, A. A., Kinney, K. S., Hing, T. C., Sapolsky, R. M. (2007) Characterization of monocyte chemoattractant protein-1 expression following a kainate model of status epilepticus. Brain Res. 1182, 138-143.
    • (2007) Brain Res. , vol.1182 , pp. 138-143
    • Manley, N.C.1    Bertrand, A.A.2    Kinney, K.S.3    Hing, T.C.4    Sapolsky, R.M.5
  • 283
    • 79953703183 scopus 로고    scopus 로고
    • Role of CCR5 and its ligands in the control of vascular inflammation and leukocyte recruitment required for acute excitotoxic seizure induction and neural damage
    • Epub ahead of print
    • Louboutin, J. P., Chekmasova, A., Marusich, E., Agrawal, L., Strayer, D. S. (2010) Role of CCR5 and its ligands in the control of vascular inflammation and leukocyte recruitment required for acute excitotoxic seizure induction and neural damage. FASEB J., Epub ahead of print.
    • (2010) FASEB J.
    • Louboutin, J.P.1    Chekmasova, A.2    Marusich, E.3    Agrawal, L.4    Strayer, D.S.5
  • 284
    • 57349100348 scopus 로고    scopus 로고
    • Brain inflammation initiates seizures
    • Kleen, J. K., Holmes, G. L. (2008) Brain inflammation initiates seizures. Nat. Med. 14, 1309-1310.
    • (2008) Nat. Med. , vol.14 , pp. 1309-1310
    • Kleen, J.K.1    Holmes, G.L.2


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