Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment

Brain

Volumn 129, Issue 1, 2006, Pages 200-211

  Krumbholz, Markus ^a,b   Theil, Diethilde ^c   Cepok, Sabine ^d   Hemmer, Bernhard ^d   Kivisäkk, Pia ^e   Ransohoff, Richard M ^e   Hofbauer, Monika ^b   Farina, Cinthia ^a   Derfuss, Tobias ^a,b   Hartle, Caroline ^f   Newcombe, Jia ^f   Hohlfeld, Reinhard ^a,b   Meinl, Edgar ^a,b  

^a MAX PLANCK INSTITUTE OF NEUROBIOLOGY   (Germany)

^b Institute of Clinical Neuroimmunology   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

^d HEINRICH HEINE UNIVERSITY   (Germany)

^e LERNER RESEARCH INSTITUTE   (United States)

^f UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Cerebrospinal fluid; Chemokines; Immune cell migration; Inflammation; Lymphocytes

Indexed keywords

AUTACOID; CHEMOKINE; CHEMOKINE RECEPTOR CXCR4; CXC CHEMOKINE LIGAND 13; CYCLOPHOSPHAMIDE; GAMMA INTERFERON; IMMUNOGLOBULIN; INTERLEUKIN 1BETA; INTERLEUKIN 4; MESSENGER RNA; METALLOPROTEINASE; NEUROTOXIN; OKT 4; STROMAL CELL DERIVED FACTOR 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADULT; ARTICLE; ASTROCYTE; AXONAL INJURY; B LYMPHOCYTE; BLAST CELL; BLOOD VESSEL WALL; CELL DIFFERENTIATION; CELL INFILTRATION; CELL MIGRATION; CEREBROSPINAL FLUID; CHRONIC DISEASE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; EXTRAVASATION; GENE EXPRESSION REGULATION; GENETIC LINKAGE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCOMPETENT CELL; IMMUNOGLOBULIN PRODUCTION; IMMUNOHISTOLOGY; LYMPHOID TISSUE; MONOCYTE; MULTIPLE SCLEROSIS; NERVOUS SYSTEM INFLAMMATION; PARENCHYMA; PLASMA CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN TARGETING; QUANTITATIVE ASSAY; REFLEX RECRUITMENT; T LYMPHOCYTE; UPREGULATION;

ACUTE DISEASE; ADULT; B-LYMPHOCYTES; CASE-CONTROL STUDIES; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; CHEMOKINES; CHEMOKINES, CXC; CHEMOTAXIS, LEUKOCYTE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOGLOBULINS; IMMUNOHISTOCHEMISTRY; INTERFERON TYPE II; INTERLEUKIN-1; INTERLEUKIN-4; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; POLYMERASE CHAIN REACTION; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 30344446249     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awh680     Document Type: Article

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