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Volumn 28, Issue 10, 1997, Pages 1948-1950

Activated microglial cells are colocalized with perivascular deposits of amyloid-β protein in Alzheimer's disease brain'

Author keywords

Alzheimer's disease; Confocal; Microglia; Microscopy

Indexed keywords

AMYLOID BETA PROTEIN;

EID: 0030691019     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.28.10.1948     Document Type: Article
Times cited : (79)

References (25)
  • 2
    • 0023809230 scopus 로고
    • Alzheimer's disease: A double-labeling immunohistochemical study of senile plaques
    • Dickson DW, Farlo J, Davies P, Crystal H, Fuld P, Yen SC. Alzheimer's disease: a double-labeling immunohistochemical study of senile plaques. Am J Pathol. 1988;132:86-101.
    • (1988) Am J Pathol. , vol.132 , pp. 86-101
    • Dickson, D.W.1    Farlo, J.2    Davies, P.3    Crystal, H.4    Fuld, P.5    Yen, S.C.6
  • 3
    • 0024573330 scopus 로고
    • Demonstration of microglial cells in and around senile (neuritic) plaques in Alzheimer brain: An immunohistochemical study using a novel monoclonal antibody
    • Haga S, Akai K, Ishii T. Demonstration of microglial cells in and around senile (neuritic) plaques in Alzheimer brain: an immunohistochemical study using a novel monoclonal antibody. Acta Neuropath (Berl). 1989;77:569-575.
    • (1989) Acta Neuropath (Berl). , vol.77 , pp. 569-575
    • Haga, S.1    Akai, K.2    Ishii, T.3
  • 4
    • 0024436506 scopus 로고
    • Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease
    • Itagaki S, McGeer PL, Akiyama H, Zhu S, Selkoe D. Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease. J Neuroimmunol. 1989;24:173-182.
    • (1989) J Neuroimmunol. , vol.24 , pp. 173-182
    • Itagaki, S.1    McGeer, P.L.2    Akiyama, H.3    Zhu, S.4    Selkoe, D.5
  • 6
    • 0025095717 scopus 로고
    • Morphologic association between microglia and senile plaque amyloid in Alzheimer's disease
    • Perlmutter LS, Barron E, Chui HC. Morphologic association between microglia and senile plaque amyloid in Alzheimer's disease. Neurosci Lett. 1990;119:32-36.
    • (1990) Neurosci Lett. , vol.119 , pp. 32-36
    • Perlmutter, L.S.1    Barron, E.2    Chui, H.C.3
  • 7
    • 0025077080 scopus 로고
    • Molecular, cellular, and pathologic characterization of HLA-DR immunoreactivity in normal elderly and Alzheimer's disease brain
    • Styren SD, Civin WH, Rogers J. Molecular, cellular, and pathologic characterization of HLA-DR immunoreactivity in normal elderly and Alzheimer's disease brain. Exp Neurol. 1990;110:93-104.
    • (1990) Exp Neurol. , vol.110 , pp. 93-104
    • Styren, S.D.1    Civin, W.H.2    Rogers, J.3
  • 8
    • 0025676284 scopus 로고
    • The complex of microglial cells and amyloid star in three- dimensional reconstruction
    • Wegiel J, Wisniewski HM. The complex of microglial cells and amyloid star in three- dimensional reconstruction. Acta Neuropathol (Berl). 1990;81:116-124.
    • (1990) Acta Neuropathol (Berl). , vol.81 , pp. 116-124
    • Wegiel, J.1    Wisniewski, H.M.2
  • 9
    • 0025789126 scopus 로고
    • A comparative immunohistochemical study of Kuru and senile plaques with a special reference to glial reactions at various stages of amyloid plaque formation
    • Miyazono M, Iwaki T, Kitamoto T, Kaneko Y, Doh-ura K, Tateishi J. A comparative immunohistochemical study of Kuru and senile plaques with a special reference to glial reactions at various stages of amyloid plaque formation. Am J Pathol. 1991;139:589-598.
    • (1991) Am J Pathol. , vol.139 , pp. 589-598
    • Miyazono, M.1    Iwaki, T.2    Kitamoto, T.3    Kaneko, Y.4    Doh-ura, K.5    Tateishi, J.6
  • 11
    • 0019955625 scopus 로고
    • The relationship between senile plaques and cerebral blood vessels in Alzheimer's disease and senile dementia: Morphological mechanism of senile plaque production
    • Miyakawa T, Shimoji A, Kumamoto R, Higuchi Y. The relationship between senile plaques and cerebral blood vessels in Alzheimer's disease and senile dementia: morphological mechanism of senile plaque production. Virchows Arch [Cell Pathol]. 1982;40:121-129.
    • (1982) Virchows Arch [Cell Pathol]. , vol.40 , pp. 121-129
    • Miyakawa, T.1    Shimoji, A.2    Kumamoto, R.3    Higuchi, Y.4
  • 12
    • 0020450904 scopus 로고
    • Amyloid and senile plaques and cerebral blood vessels: A semi-quantitative investigation of a possible relationship
    • Mountjoy CQ. Amyloid and senile plaques and cerebral blood vessels: a semi-quantitative investigation of a possible relationship J Neurol Sci. 1982;57:89-103.
    • (1982) J Neurol Sci. , vol.57 , pp. 89-103
    • Mountjoy, C.Q.1
  • 13
    • 0025665181 scopus 로고
    • The relationship of amyloid plaques to cerebral capillaries in Alzheimer's disease
    • Kawai M, Kalaria RN, Harik SI, Perry G. The relationship of amyloid plaques to cerebral capillaries in Alzheimer's disease. Am J Pathol. 1990;137:1435-1446.
    • (1990) Am J Pathol. , vol.137 , pp. 1435-1446
    • Kawai, M.1    Kalaria, R.N.2    Harik, S.I.3    Perry, G.4
  • 14
    • 0028878620 scopus 로고
    • Single laser, three color immunolabeling of a histological section with laser scanning microscopy: Application to senile plaque related structures
    • Uchihara T, Kondo H, Akiyama H, Ikeda K. Single laser, three color immunolabeling of a histological section with laser scanning microscopy: application to senile plaque related structures. J Histochem Cytochem. 1995;43:103-106.
    • (1995) J Histochem Cytochem. , vol.43 , pp. 103-106
    • Uchihara, T.1    Kondo, H.2    Akiyama, H.3    Ikeda, K.4
  • 15
    • 0030003487 scopus 로고    scopus 로고
    • Granules in glial cells of patients with Alzheimer's disease are immunopositive for C-terminal sequences of beta-amyloid protein
    • Akiyama H, Schwab C, Kondo H, Mori H, Kametani H, Ikeda K, McGeer PL. Granules in glial cells of patients with Alzheimer's disease are immunopositive for C-terminal sequences of beta-amyloid protein. Neurosci Lett. 1996;206:169-172.
    • (1996) Neurosci Lett. , vol.206 , pp. 169-172
    • Akiyama, H.1    Schwab, C.2    Kondo, H.3    Mori, H.4    Kametani, H.5    Ikeda, K.6    McGeer, P.L.7
  • 16
    • 0030248270 scopus 로고    scopus 로고
    • Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor
    • Paresce DM, Ghosh RN, Maxfield FR. Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor. Neuron. 1996;17:553-565.
    • (1996) Neuron. , vol.17 , pp. 553-565
    • Paresce, D.M.1    Ghosh, R.N.2    Maxfield, F.R.3
  • 17
    • 0026783591 scopus 로고
    • Ultrastructure of the microglia that phagocytose amyloid and the microglia that produce beta-amyloid fibrils
    • Frackowiak J, Wisniewski HM, Wegiel J, Merz GS, Iqbal K, Wang C. Ultrastructure of the microglia that phagocytose amyloid and the microglia that produce beta-amyloid fibrils. Acta Neuropathol (Berl). 1992;84:225-233.
    • (1992) Acta Neuropathol (Berl). , vol.84 , pp. 225-233
    • Frackowiak, J.1    Wisniewski, H.M.2    Wegiel, J.3    Merz, G.S.4    Iqbal, K.5    Wang, C.6
  • 18
    • 0027099863 scopus 로고
    • The amyloid beta-protein of Alzheimer's disease is chemotactic for mononuclear phagocytes
    • Davis JB, McMurray HF, Schubert D. The amyloid beta-protein of Alzheimer's disease is chemotactic for mononuclear phagocytes. Biochem Biophys Res Commun. 1992;189:1096-1100.
    • (1992) Biochem Biophys Res Commun. , vol.189 , pp. 1096-1100
    • Davis, J.B.1    McMurray, H.F.2    Schubert, D.3
  • 19
    • 0028261779 scopus 로고
    • Expression of MRP14, 27E10, interferon-alpha and leukocyte common antigen by reactive microglia in postmortem human brain tissue
    • Akiyama H, Ikeda K, Katoh M, McGeer EG, McGeer PL. Expression of MRP14, 27E10, interferon-alpha and leukocyte common antigen by reactive microglia in postmortem human brain tissue. J Neuroimmunol. 1994;50:195-201.
    • (1994) J Neuroimmunol. , vol.50 , pp. 195-201
    • Akiyama, H.1    Ikeda, K.2    Katoh, M.3    McGeer, E.G.4    McGeer, P.L.5
  • 21
    • 0029610011 scopus 로고
    • The inflammatory response system of brain: Implications for therapy of Alzheimer and other neurodegenerative diseases
    • McGeer PL, McGeer EG. The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases. Brain Res Rev. 1995;21:195-218.
    • (1995) Brain Res Rev. , vol.21 , pp. 195-218
    • McGeer, P.L.1    McGeer, E.G.2
  • 24
    • 0026551329 scopus 로고
    • Anti-inflammatory agents as a therapeutic approach to Alzheimer's disease
    • McGeer PL, Rogers J. Anti-inflammatory agents as a therapeutic approach to Alzheimer's disease. Neurology. 1992;42:447-449.
    • (1992) Neurology , vol.42 , pp. 447-449
    • McGeer, P.L.1    Rogers, J.2
  • 25
    • 0027268393 scopus 로고
    • Clinical trial of indomethacin in Alzheimer's disease
    • Rogers J, Kirby LC, Hempelman SR. Clinical trial of indomethacin in Alzheimer's disease. Neurology. 1993;43:1609-1611.
    • (1993) Neurology , vol.43 , pp. 1609-1611
    • Rogers, J.1    Kirby, L.C.2    Hempelman, S.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.