LAU-0901, a novel platelet-activating factor antagonist, is highly neuroprotective in cerebral ischemia

Experimental Neurology

Volumn 214, Issue 2, 2008, Pages 253-258

  Belayev, Ludmila ^a   Khoutorova, Larissa ^a   Atkins, Kristal ^a   Gordon, William C ^a   Alvarez Builla, Julio ^b   Bazan, Nicolas G ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b UNIVERSITY OF ALCALÁ   (Spain)

Author keywords

Behavioral; Histopathology; LAU 0901; Local cerebral blood flow; Middle cerebral artery occlusion; PAF antagonist

Indexed keywords

2,4,6 TRIMETHYL 1,4 DIHYDRO 3,5 PYRIDINEDICARBOXYLIC ACID 2 (3,4 DICHLOROPHENOXY)ETHYL BIS(MORPHOLINOMETHYL)METHYL ESTER; 2,4,6 TRIMETHYL 1,4 DIHYDRO PYRIDINE 3,5 DICARBOXYLIC ACID; DEXTRAN; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD FLOW; BRAIN INFARCTION; BRAIN ISCHEMIA; CENTRAL NERVOUS SYSTEM FUNCTION; CONTROLLED STUDY; DOSE RESPONSE; DRUG STRUCTURE; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; SPRAGUE DAWLEY RAT; SURVIVAL TIME;

ACUTE DISEASE; ANIMALS; BEHAVIOR, ANIMAL; BRAIN ISCHEMIA; CEREBROVASCULAR CIRCULATION; DIHYDROPYRIDINES; DOSE-RESPONSE RELATIONSHIP, DRUG; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MICE; MICE, INBRED C57BL; NEOCORTEX; NEUROPROTECTIVE AGENTS; PLATELET ACTIVATING FACTOR; RATS; RATS, SPRAGUE-DAWLEY;

EID: 56349131188     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2008.08.009     Document Type: Article

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