Prevention of a chronic progressive form of experimental autoimmune encephalomyelitis by an antibody against mucosal addressin cell adhesion molecule-1, given early in the course of disease progression

Immunology and Cell Biology

Volumn 78, Issue 6, 2000, Pages 641-645

  Kanwar, J R ^a   Kanwar, R K ^a   Wang, D ^a   Krissansen, G W ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Demyelination; Experimental autoimmune encephalomyelitis; Inflammation; Mucosal addressin cell adhesion molecule 1; Multiple sclerosis; Vascular addressin

Indexed keywords

ADDRESSIN; AUTOANTIGEN; BETA1 INTEGRIN; INTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1 ANTIBODY; LIGAND; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MONOCLONAL ANTIBODY; MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1; MYELIN ASSOCIATED GLYCOPROTEIN; UVOMORULIN; VASCULAR CELL ADHESION MOLECULE 1;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; BLOOD BRAIN BARRIER; CENTRAL NERVOUS SYSTEM; CHRONIC DISEASE; CONTROLLED STUDY; DEMYELINATION; DISEASE COURSE; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PROTEIN EXPRESSION; REMISSION;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL ADHESION MOLECULES; CHRONIC DISEASE; DISEASE PROGRESSION; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; IMMUNOGLOBULINS; INTERCELLULAR ADHESION MOLECULE-1; LEUKOCYTES; MICE; MICE, INBRED C57BL; MUCOPROTEINS; SPINAL CORD; TIME FACTORS; VASCULAR CELL ADHESION MOLECULE-1;

ANIMALIA;

EID: 0033667644     PISSN: 08189641     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1711.2000.00947.x     Document Type: Article

References (24)

1. Peyer's patch-specific lymphocyte homing receptors consist of a VLA-4-like α chain associated with either of two integrin β chains, one of which is novel
2. Molecular cloning of the mouse integrin β7 subunit
3. A family of β7 integrins on human mucosal lymphocytes
4. Immunologic and structural relatedness of the integrin β7 complex and the human intraepithelial lymphocyte antigen HML-1
5. α4β7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1
6. MAdCAM-1 has homology to immunoglobulin and mucin-like adhesion receptors and to IgA1
7. Construction and adhesive properties of a soluble MAdCAM-1-Fc chimera expressed in a baculovirus system: Phylogenetic conservation of receptorligand interaction
8. Critical role for β7 integrins in the formation of the gut associated lymphoid tissue
9. Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the αEβ7 integrin
10. Recognition of E-cadherin on epithelial cells by the mucosal T cell integrin αM290β7 (αEβ7)
11. Lymphocyte function associated antigen-1, integrin α4, and L-selectin mediate T-cell homing to the pancreas in the model of adoptive transfer of diabetes in NOD mice
12. Involvement of β7 integrin and mucosal addressin cell adhesion molecule-1 (MAdCAM-1) in the development of diabetes in non-obese diabetic mice
13. Prevention of experimental autoimmune encephalomyelitis by antibodies against α4β1 integrin
14. Suppression of experimental autoimmune encephalomyelitis with a TNF binding protein (TNFbp) correlates with down-regulation of VCAM-1/VLA-4
15. The effect of anti-α4 integrin antibody on brain lesion activity in MS
16. Contributory role for β7 integrins in non-remitting experimental autoimmune encephalomyelitis
17. Relapsing autoimmune demyelination: A role for vascular addressins
18. A critical role for lymphotoxin in experimental allergic encephalomyelitis
19. Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis
20. The accessory function of murine intercellular adhesion molecule-1 in T lymphocyte activation
21. A myelin oligodendrocyte glycoprotein peptide induces typical chronic experimental autoimmune encephalomyelitis in H-2b mice: Fine specificity and T cell receptor Vβ expression of encephalitogenic T cells
22. Surface expression of α4 integrin by CD4 T cells is required for their entry into brain parenchyma
23. Specialization of mucosal follicular dendritic cells revealed by mucosal addressin-cell adhesion molecule-1 display
24. Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) costimulates T cell proliferation exclusively through integrin α4β7 (LPAM-1), whereas VCAM-1 and CS-1 peptide use α4β1 (VLA-4): Evidence for 'remote' costimulation and induction of hyperresponsiveness to B7 molecules