Road towards new antimalarials -Overview of the strategies and their chemical progress

Current Medicinal Chemistry

Volumn 18, Issue 6, 2011, Pages 853-871

  Wu, Tao ^a   Nagle, Advait S ^a   Chatterjee, Arnab K ^a  

^a Research Foundation   (United States)

Author keywords

Aminoquinoline; Artemisinin; DHODH; Drug resistance; Farnesyl transferase; Hybrid compounds; Malaria; Plasmodium

Indexed keywords

1,2,4 TRIOXANE DERIVATIVE; AMINODIAQUINE; AMODIAQUINE; ANTIMALARIAL AGENT; ARTEETHER; ARTELINIC ACID; ARTEMETHER; ARTEMETHER PLUS BENFLUMETOL; ARTEMISININ; ARTEMISININ DERIVATIVE; ARTEMISONE; ARTEROLANE; ARTESUNATE; CHLOROQUINE; DIHYDROARTEMISININ DERIVATIVE; DIHYDROOROTATE DEHYDROGENASE INHIBITOR; ENDOPEROXIDE; FERROQUINE; GSK 369796; ISOQUINE; MEFLOQUINE; PRIMAQUINE; PROTEIN FARNESYLTRANSFERASE INHIBITOR; PROTEIN KINASE INHIBITOR; QUINOLINE DERIVATIVE; SULFONE DERIVATIVE; TAFENOQUINE; TETRAHYDROQUINOLINE DERIVATIVE; TRIOXAQUINE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; DERIVATIZATION; DRUG BIOAVAILABILITY; DRUG EFFICACY; DRUG HALF LIFE; DRUG INDICATION; DRUG POTENCY; DRUG SAFETY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; GENOTOXICITY; HEMOLYSIS; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MALARIA; MALARIA FALCIPARUM; NEUROTOXICITY; NONHUMAN; PATIENT COMPLIANCE; PHARMACOPHORE; PLASMODIUM BERGHEI; PLASMODIUM BERGHEI INFECTION; PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX MALARIA; PLASMODIUM YOELII INFECTION; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIMALARIALS; CELL LINE; DRUG DISCOVERY; HUMANS;

EID: 79952804083     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986711794927748     Document Type: Article

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