Fluoroartemisinin: Trifluoromethyl Analogues of Artemether and Artesunate

Journal of Medicinal Chemistry

Volumn 47, Issue 10, 2004, Pages 2694-2699

  Magueur, Guillaume ^a   Crousse, Benoit ^a   Charneau, Sébastien ^b   Grellier, Philippe ^b   Bégué, Jean Pierre ^a   Bonnet Delpon, Danièle ^a  

^a UNIVERSITÉ PARIS SUD   (France)

^b MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

10BETA (2 OXOETHOXY) 10ALPHA TRIFLUOROMETHYLDEOXOARTEMISININ; 10BETA (2,3 DIHYDROXYPROPOXY) 10ALPHA TRIFLUOROMETHYLDEOXOARTEMISININ; 10BETA (4 METHOXYPHENYLAMINO) 10ALPHA TRIFLUOROMETHYLDEOXOARTEMISININ; 10BETA CARBOXYMETHOXY 10ALPHA TRIFLUOROMETHYLDEOXOARTEMISININ; ALCOHOL; ANTIMALARIAL AGENT; ARTEMETHER; ARTEMISININ DERIVATIVE; ARTESUNATE; BROMIDE; CHLOROQUINE; METHANOL; SUCCINIC ACID; TRIFLUOROMETHYL HYDROARTEMISININ; UNCLASSIFIED DRUG;

AEROBIC METABOLISM; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG HALF LIFE; DRUG STABILITY; DRUG SYNTHESIS; FEMALE; IN VITRO STUDY; IN VIVO STUDY; LIPOPHILICITY; MOUSE; NONHUMAN; PARASITEMIA; PLASMODIUM BERGHEI; TREATMENT OUTCOME;

ANIMALS; ANTIMALARIALS; ARTEMISININS; DRUG STABILITY; FLUORINE; HYDROLYSIS; MALARIA; MICE; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; SESQUITERPENES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 2342517468     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0310333     Document Type: Article

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