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Volumn 2, Issue 4, 2002, Pages 388-393

Farnesyltransferase inhibitors: Promises and realities

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOPLATIN; FARNESYL TRANS TRANSFERASE; IMATINIB; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN FARNESYLTRANSFERASE INHIBITOR; RAS PROTEIN; RHOB GUANINE NUCLEOTIDE BINDING PROTEIN; TAXANE DERIVATIVE; TRASTUZUMAB; ENZYME INHIBITOR; TRANSFERASE;

EID: 0036667388     PISSN: 14714892     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1471-4892(02)00181-9     Document Type: Review
Times cited : (130)

References (64)
  • 13
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    • Farnesyltransferase inhibitors: Potential role in the treatment of cancer
    • (2001) Drugs , vol.61 , pp. 723-732
    • Cox, A.D.1
  • 19
    • 0032546264 scopus 로고    scopus 로고
    • Both farnesyltransferase and geranylgeranyltransferase I inhibitors are required for inhibition of oncogenic K-Ras prenylation but each alone is sufficient to suppress human tumor growth in nude mouse xenografts
    • (1998) Oncogene , vol.16 , pp. 1467-1473
    • Sun, J.1    Qian, Y.2    Hamilton, A.D.3    Sebti, S.M.4
  • 30
    • 0025831433 scopus 로고
    • The ras-related gene rhoB is an immediate-early gene inducible by v-Fps, epidermal growth factor, and platelet-derived growth factor in rat fibroblasts
    • (1991) Mol. Cell Biol , vol.11 , pp. 3682-3690
    • Jahner, D.1    Hunter, T.2
  • 36
    • 85031451654 scopus 로고    scopus 로고
    • RhoB is transcriptionally induced by farnesyltransferase and geranylgeranyltransferase I inhibitors: Induction of RhoB does not correlate with human cancer cell growth inhibition
    • Proceedings of the 93rd Annual Meeting of the American Association for Cancer Research 2002 April 6-10, San Francisco. Philadelphia: American Association of Cancer Research
    • , vol.43 , pp. 337
    • Delarue, F.L.1    Adnane, J.2    Bizouarn, F.3    Ohkanda, J.4    Hamilton, A.D.5    Sebti, S.M.6
  • 48
    • 0034846550 scopus 로고    scopus 로고
    • Farnesyl protein transferase inhibitors as targeted therapies for hematologic malignancies
    • (2001) Semin. Hematol , vol.38 , pp. 16-23
    • Karp, J.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.