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Volumn 30, Issue 1, 2011, Pages 125-140

Improving cancer immunotherapy by targeting tumor-induced immune suppression

Author keywords

Immune suppression; Immunotherapy; Inhibitory cytokines; MDSC; Tumor immunology

Indexed keywords

ADENOSINE; ARGINASE 1; CYCLOOXYGENASE 2; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DIOXYGENASE; INDOLEAMINE 2,2 DIOXYGENASE; INTERLEUKIN 10; MONOCYTE CHEMOTACTIC PROTEIN 1; NITRIC OXIDE SYNTHASE; PROGRAMMED DEATH 1 RECEPTOR; PROSTAGLANDIN E2; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 79952281795     PISSN: 01677659     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10555-011-9280-5     Document Type: Article
Times cited : (130)

References (157)
  • 1
    • 33846972342 scopus 로고    scopus 로고
    • Immunological responses can have both pro- and antitumour effects: Implications for immunotherapy
    • DOI 10.1017/S1462399407000233, PII S1462399407000233
    • TJ Stewart KM Greeneltch ME Lutsiak SI Abrams 2007 Immunological responses can have both pro- and antitumour effects: implications for immunotherapy Expert Reviews in Molecular Medicine 9 4 1 20 10.1017/ S1462399407000233 17284328 (Pubitemid 46242913)
    • (2007) Expert Reviews in Molecular Medicine , vol.9 , Issue.4 , pp. 1-20
    • Stewart, T.J.1    Greeneltch, K.M.2    Lutsiak, M.E.C.3    Abrams, S.I.4
  • 2
    • 72649104033 scopus 로고    scopus 로고
    • Immune surveillance of human cancer: If the cytotoxic t-lymphocytes play the music, does the tumoral system call the tune?
    • doi: 10.1111/j.1399-0039.2009.01401.x
    • Hamai, A., Benlalam, H., Meslin, F., Hasmim, M., Carre, T., Akalay, I., et al. Immune surveillance of human cancer: If the cytotoxic t-lymphocytes play the music, does the tumoral system call the tune? Tissue Antigens, 75(1), 1-8, doi: 10.1111/j.1399-0039.2009.01401.x.
    • Tissue Antigens , vol.75 , Issue.1 , pp. 1-8
    • Hamai, A.1    Benlalam, H.2    Meslin, F.3    Hasmim, M.4    Carre, T.5    Akalay, I.6
  • 3
    • 22144439081 scopus 로고    scopus 로고
    • Tumor antigen-specific T helper cells in cancer immunity and immunotherapy
    • DOI 10.1007/s00262-004-0653-2
    • KL Knutson ML Disis 2005 Tumor antigen-specific T helper cells in cancer immunity and immunotherapy Cancer Immunology, Immunotherapy 54 8 721 728 16010587 1:CAS:528:DC%2BD2MXmtVajt78%3D (Pubitemid 40977140)
    • (2005) Cancer Immunology, Immunotherapy , vol.54 , Issue.8 , pp. 721-728
    • Knutson, K.L.1    Disis, M.L.2
  • 5
    • 4143141823 scopus 로고    scopus 로고
    • The immunobiology of cancer immunosurveillance and immunoediting
    • DOI 10.1016/j.immuni.2004.07.017, PII S1074761304002092
    • GP Dunn LJ Old RD Schreiber 2004 The immunobiology of cancer immunosurveillance and immunoediting Immunity 21 2 137 148 15308095 1:CAS:528:DC%2BD2cXnsVKltrY%3D (Pubitemid 39094044)
    • (2004) Immunity , vol.21 , Issue.2 , pp. 137-148
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 6
    • 34248193253 scopus 로고    scopus 로고
    • Immune surveillance of tumors
    • DOI 10.1172/JCI31405
    • JB Swann MJ Smyth 2007 Immune surveillance of tumors Journal of Clinical Investigation 117 5 1137 1146 10.1172/JCI31405 17476343 1:CAS:528: DC%2BD2sXlt1Omtr0%3D (Pubitemid 46718398)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.5 , pp. 1137-1146
    • Swann, J.B.1    Smyth, M.J.2
  • 7
    • 36048959304 scopus 로고    scopus 로고
    • Tumor Microenvironment and Immune Escape
    • DOI 10.1016/j.soc.2007.08.004, PII S1055320707000981, Tumor Immunology for the Practicing Surgeon
    • Ferrone, S., & Whiteside, T. L. (2007). Tumor microenvironment and immune escape. Surgical Oncology Clinics of North America, 16(4), 755-774, viii, doi: 10.1016/j.soc.2007.08.004. (Pubitemid 350101281)
    • (2007) Surgical Oncology Clinics of North America , vol.16 , Issue.4 , pp. 755-774
    • Ferrone, S.1    Whiteside, T.L.2
  • 8
    • 53549087527 scopus 로고    scopus 로고
    • How tumours escape mass destruction
    • 10.1038/onc.2008.268 18836470 1:CAS:528:DC%2BD1cXhtF2msbbJ
    • TJ Stewart SI Abrams 2008 How tumours escape mass destruction Oncogene 27 45 5894 5903 10.1038/onc.2008.268 18836470 1:CAS:528:DC%2BD1cXhtF2msbbJ
    • (2008) Oncogene , vol.27 , Issue.45 , pp. 5894-5903
    • Stewart, T.J.1    Abrams, S.I.2
  • 9
    • 77951614830 scopus 로고    scopus 로고
    • Monoclonal antibodies: Versatile platforms for cancer immunotherapy
    • doi: 10.1038/nri2744
    • Weiner, L. M., Surana, R., & Wang, S. Monoclonal antibodies: versatile platforms for cancer immunotherapy. Nature Reviews. Immunology, 10(5), 317-327, doi: 10.1038/nri2744.
    • Nature Reviews. Immunology , vol.10 , Issue.5 , pp. 317-327
    • Weiner, L.M.1    Surana, R.2    Wang, S.3
  • 10
    • 73949096501 scopus 로고    scopus 로고
    • Cellular therapy to control tumor progression
    • 10.1097/MOH.0b013e32832f57d4 19587587
    • M Kapp L Rasche H Einsele GU Grigoleit 2009 Cellular therapy to control tumor progression Current Opinion in Hematology 16 6 437 443 10.1097/MOH.0b013e32832f57d4 19587587
    • (2009) Current Opinion in Hematology , vol.16 , Issue.6 , pp. 437-443
    • Kapp, M.1    Rasche, L.2    Einsele, H.3    Grigoleit, G.U.4
  • 11
    • 65249173447 scopus 로고    scopus 로고
    • Adoptive cell therapy for the treatment of patients with metastatic melanoma
    • 10.1016/j.coi.2009.03.002 19304471 1:CAS:528:DC%2BD1MXlsVCgtb8%3D
    • SA Rosenberg ME Dudley 2009 Adoptive cell therapy for the treatment of patients with metastatic melanoma Current Opinion in Immunology 21 2 233 240 10.1016/j.coi.2009.03.002 19304471 1:CAS:528:DC%2BD1MXlsVCgtb8%3D
    • (2009) Current Opinion in Immunology , vol.21 , Issue.2 , pp. 233-240
    • Rosenberg, S.A.1    Dudley, M.E.2
  • 12
    • 77956622836 scopus 로고    scopus 로고
    • Designing t cells for cancer immunotherapy
    • Huye, L. E., & Dotti, G. Designing t cells for cancer immunotherapy. Discov Med, 9(47), 297-303.
    • Discov Med , vol.9 , Issue.47 , pp. 297-303
    • Huye, L.E.1    Dotti, G.2
  • 13
    • 77952484156 scopus 로고    scopus 로고
    • Genetic redirection of t cells for cancer therapy
    • doi: 10.1189/jlb.1209824
    • Westwood, J. A., & Kershaw, M. H. Genetic redirection of t cells for cancer therapy. Journal of Leukocyte Biology, 87(5), 791-803, doi: 10.1189/jlb.1209824.
    • Journal of Leukocyte Biology , vol.87 , Issue.5 , pp. 791-803
    • Westwood, J.A.1    Kershaw, M.H.2
  • 15
    • 70350376860 scopus 로고    scopus 로고
    • Properties and origin of human th17 cells
    • 10.1016/j.molimm.2008.12.019 19193443 1:CAS:528:DC%2BD1MXhtleksb3E
    • S Romagnani E Maggi F Liotta L Cosmi F Annunziato 2009 Properties and origin of human th17 cells Molecular Immunology 47 1 3 7 10.1016/j.molimm.2008. 12.019 19193443 1:CAS:528:DC%2BD1MXhtleksb3E
    • (2009) Molecular Immunology , vol.47 , Issue.1 , pp. 3-7
    • Romagnani, S.1    Maggi, E.2    Liotta, F.3    Cosmi, L.4    Annunziato, F.5
  • 17
    • 77954721060 scopus 로고    scopus 로고
    • Regulatory t cells in tumor immunity
    • doi: 10.1002/ijc.25429
    • Nishikawa, H., & Sakaguchi, S. Regulatory t cells in tumor immunity. International Journal of Cancer, 127(4), 759-767, doi: 10.1002/ijc.25429.
    • International Journal of Cancer , vol.127 , Issue.4 , pp. 759-767
    • Nishikawa, H.1    Sakaguchi, S.2
  • 19
    • 31344474166 scopus 로고    scopus 로고
    • Myeloid suppressor cells in cancer: Recruitment, phenotype, properties, and mechanisms of immune suppression
    • DOI 10.1016/j.semcancer.2005.07.005, PII S1044579X05000581, The Inflamation-Cancer Linkage: A Double-Edged Sword?
    • P Serafini I Borrello V Bronte 2006 Myeloid suppressor cells in cancer: recruitment, phenotype, properties, and mechanisms of immune suppression Seminars in Cancer Biology 16 1 53 65 16168663 1:CAS:528:DC%2BD28XotVCmuw%3D%3D (Pubitemid 43139709)
    • (2006) Seminars in Cancer Biology , vol.16 , Issue.1 , pp. 53-65
    • Serafini, P.1    Borrello, I.2    Bronte, V.3
  • 20
    • 41149164902 scopus 로고    scopus 로고
    • The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance
    • DOI 10.1111/j.1600-065X.2008.00607.x
    • P Allavena A Sica C Garlanda A Mantovani 2008 The yin-yang of tumor-associated macrophages in neoplastic progression and immune surveillance Immunological Reviews 222 155 161 10.1111/j.1600-065X.2008.00607.x 18364000 1:CAS:528:DC%2BD1cXlsFejtrc%3D (Pubitemid 351430369)
    • (2008) Immunological Reviews , vol.222 , Issue.1 , pp. 155-161
    • Allavena, P.1    Sica, A.2    Garlanda, C.3    Mantovani, A.4
  • 21
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • 10.1038/nri2506 19197294 1:CAS:528:DC%2BD1MXhsFeqsbw%3D
    • DI Gabrilovich S Nagaraj 2009 Myeloid-derived suppressor cells as regulators of the immune system Nature Reviews. Immunology 9 3 162 174 10.1038/nri2506 19197294 1:CAS:528:DC%2BD1MXhsFeqsbw%3D
    • (2009) Nature Reviews. Immunology , vol.9 , Issue.3 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 22
    • 41149119143 scopus 로고    scopus 로고
    • Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells
    • DOI 10.1111/j.1600-065X.2008.00602.x
    • I Marigo L Dolcetti P Serafini P Zanovello V Bronte 2008 Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells Immunological Reviews 222 162 179 10.1111/j.1600-065X.2008.00602.x 18364001 1:CAS:528:DC%2BD1cXlsFejt74%3D (Pubitemid 351430364)
    • (2008) Immunological Reviews , vol.222 , Issue.1 , pp. 162-179
    • Marigo, I.1    Dolcetti, L.2    Serafini, P.3    Zanovello, P.4    Bronte, V.5
  • 24
    • 54849440346 scopus 로고    scopus 로고
    • Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy
    • 10.1007/s00262-008-0523-4 18446337 1:CAS:528:DC%2BD1cXht1yqs7bN
    • CM Diaz-Montero ML Salem MI Nishimura E Garrett-Mayer DJ Cole AJ Montero 2009 Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy Cancer Immunology, Immunotherapy 58 1 49 59 10.1007/s00262-008- 0523-4 18446337 1:CAS:528:DC%2BD1cXht1yqs7bN
    • (2009) Cancer Immunology, Immunotherapy , vol.58 , Issue.1 , pp. 49-59
    • Diaz-Montero, C.M.1    Salem, M.L.2    Nishimura, M.I.3    Garrett-Mayer, E.4    Cole, D.J.5    Montero, A.J.6
  • 25
    • 34248172324 scopus 로고    scopus 로고
    • Altered macrophage differentiation and immune dysfunction in tumor development
    • DOI 10.1172/JCI31422
    • A Sica V Bronte 2007 Altered macrophage differentiation and immune dysfunction in tumor development Journal of Clinical Investigation 117 5 1155 1166 10.1172/JCI31422 17476345 1:CAS:528:DC%2BD2sXlt1Omtrs%3D (Pubitemid 46718400)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.5 , pp. 1155-1166
    • Sica, A.1    Bronte, V.2
  • 26
    • 0033757517 scopus 로고    scopus 로고
    • Chemoattraction of femoral cd34+ progenitor cells by tumor-derived vascular endothelial cell growth factor
    • 1:CAS:528:DC%2BD3cXos1Orsro%3D
    • MR Young K Kolesiak MA Wright DI Gabrilovich 1999 Chemoattraction of femoral cd34+ progenitor cells by tumor-derived vascular endothelial cell growth factor Clinical & Experimental Metastasis 17 10 881 888 1:CAS:528:DC%2BD3cXos1Orsro%3D
    • (1999) Clinical & Experimental Metastasis , vol.17 , Issue.10 , pp. 881-888
    • Young, M.R.1    Kolesiak, K.2    Wright, M.A.3    Gabrilovich, D.I.4
  • 28
    • 34447258415 scopus 로고    scopus 로고
    • Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine
    • DOI 10.1200/JCO.2006.08.5829
    • P Filipazzi R Valenti V Huber L Pilla P Canese M Iero, et al. 2007 Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine Journal of Clinical Oncology 25 18 2546 2553 10.1200/JCO.2006.08.5829 17577033 1:CAS:528:DC%2BD2sXotV2mt7Y%3D (Pubitemid 47041228)
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.18 , pp. 2546-2553
    • Filipazzi, P.1    Valenti, R.2    Huber, V.3    Pilla, L.4    Canese, P.5    Iero, M.6    Castelli, C.7    Mariani, L.8    Parmiani, G.9    Rivoltini, L.10
  • 29
    • 46049098560 scopus 로고    scopus 로고
    • + T Cells
    • DOI 10.1053/j.gastro.2008.03.020, PII S0016508508004563
    • B Hoechst LA Ormandy M Ballmaier F Lehner C Kruger MP Manns, et al. 2008 A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces cd4(+)cd25(+)foxp3(+) T cells Gastroenterology 135 1 234 243 10.1053/j.gastro.2008.03.020 18485901 1:CAS:528:DC%2BD1cXps1Wltb0%3D (Pubitemid 351899008)
    • (2008) Gastroenterology , vol.135 , Issue.1 , pp. 234-243
    • Hoechst, B.1    Ormandy, L.A.2    Ballmaier, M.3    Lehner, F.4    Kruger, C.5    Manns, M.P.6    Greten, T.F.7    Korangy, F.8
  • 30
    • 1542720380 scopus 로고    scopus 로고
    • Surgical Removal of Primary Tumor Reverses Tumor-Induced Immunosuppression Despite the Presence of Metastatic Disease
    • DOI 10.1158/0008-5472.CAN-03-2646
    • EA Danna P Sinha M Gilbert VK Clements BA Pulaski S Ostrand-Rosenberg 2004 Surgical removal of primary tumor reverses tumor-induced immunosuppression despite the presence of metastatic disease Cancer Research 64 6 2205 2211 15026364 1:CAS:528:DC%2BD2cXitFCgu7g%3D (Pubitemid 38339474)
    • (2004) Cancer Research , vol.64 , Issue.6 , pp. 2205-2211
    • Danna, E.A.1    Sinha, P.2    Gilbert, M.3    Clements, V.K.4    Pulaski, B.A.5    Ostrand-Rosenberg, S.6
  • 32
    • 0027232788 scopus 로고
    • + T cell clones and resting T cells: Specific inhibition of IL-2 production and proliferation
    • de Waal Malefyt, R., Yssel, H., & de Vries, J. E. (1993). Direct effects of il-10 on subsets of human cd4+ t cell clones and resting t cells. Specific inhibition of il-2 production and proliferation. Journal of Immunology, 150(11), 4754-4765. (Pubitemid 23150343)
    • (1993) Journal of Immunology , vol.150 , Issue.11 , pp. 4754-4765
    • De Waal Malefyt, R.1    Yssel, H.2    De Vries, J.E.3
  • 33
    • 0029831666 scopus 로고    scopus 로고
    • High level IL-12 production by murine dendritic cells: Upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10
    • F Koch U Stanzl P Jennewein K Janke C Heufler E Kampgen, et al. 1996 High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10 The Journal of Experimental Medicine 184 2 741 746 8760828 1:CAS:528:DyaK28XltVCrsbY%3D (Pubitemid 26324128)
    • (1996) Journal of Experimental Medicine , vol.184 , Issue.2 , pp. 741-746
    • Koch, F.1    Stanzl, U.2    Jennewein, P.3    Janke, K.4    Heufler, C.5    Kampgen, E.6    Romani, N.7    Schuler, G.8
  • 34
    • 0035062021 scopus 로고    scopus 로고
    • Interleukin-10 and the interleukin-10 receptor
    • DOI 10.1146/annurev.immunol.19.1.683
    • KW Moore R de Waal Malefyt RL Coffman A O'Garra 2001 Interleukin-10 and the interleukin-10 receptor Annual Review of Immunology 19 683 765 10.1146/annurev.immunol.19.1.683 11244051 1:CAS:528:DC%2BD3MXivFKgu70%3D (Pubitemid 32368050)
    • (2001) Annual Review of Immunology , vol.19 , pp. 683-765
    • Moore, K.W.1    De Waal Malefyt, R.2    Coffman, R.L.3    O'Garra, A.4
  • 40
    • 68949112132 scopus 로고    scopus 로고
    • Modulating the expression of IFN regulatory factor 8 alters the protumorigenic behavior of CD11b+Gr-1+ myeloid cells
    • 10.4049/jimmunol.0804132 1:CAS:528:DC%2BD1MXnsVOrtLc%3D
    • TJ Stewart DJ Liewehr SM Steinberg KM Greeneltch SI Abrams 2009 Modulating the expression of IFN regulatory factor 8 alters the protumorigenic behavior of CD11b+Gr-1+ myeloid cells Journal of Immunology 183 1 117 128 10.4049/jimmunol.0804132 1:CAS:528:DC%2BD1MXnsVOrtLc%3D
    • (2009) Journal of Immunology , vol.183 , Issue.1 , pp. 117-128
    • Stewart, T.J.1    Liewehr, D.J.2    Steinberg, S.M.3    Greeneltch, K.M.4    Abrams, S.I.5
  • 41
    • 77449103262 scopus 로고    scopus 로고
    • Interferon regulatory factor-8 modulates the development of tumour-induced CD11B+Gr-1+ myeloid cells
    • 10.1111/j.1582-4934.2009.00685.x 20196788
    • TJ Stewart KM Greeneltch JE Reid DJ Liewehr SM Steinberg K Liu, et al. 2009 Interferon regulatory factor-8 modulates the development of tumour-induced CD11B+Gr-1+ myeloid cells Journal of Cellular and Molecular Medicine 13 9B 3939 3950 10.1111/j.1582-4934.2009.00685.x 20196788
    • (2009) Journal of Cellular and Molecular Medicine , vol.13 , Issue.9 B , pp. 3939-3950
    • Stewart, T.J.1    Greeneltch, K.M.2    Reid, J.E.3    Liewehr, D.J.4    Steinberg, S.M.5    Liu, K.6
  • 43
    • 27144538568 scopus 로고    scopus 로고
    • Regulation of dendritic cell differentiation and antitumor immune response in cancer by pharmacologic-selective inhibition of the Janus-activated kinase 2/signal transducers and activators of transcription 3 pathway
    • DOI 10.1158/0008-5472.CAN-05-0529
    • Y Nefedova S Nagaraj A Rosenbauer C Muro-Cacho SM Sebti DI Gabrilovich 2005 Regulation of dendritic cell differentiation and antitumor immune response in cancer by pharmacologic-selective inhibition of the janus-activated kinase 2/signal transducers and activators of transcription 3 pathway Cancer Research 65 20 9525 9535 16230418 1:CAS:528:DC%2BD2MXhtFWmu7rL (Pubitemid 41508023)
    • (2005) Cancer Research , vol.65 , Issue.20 , pp. 9525-9535
    • Nefedova, Y.1    Nagaraj, S.2    Rosenbauer, A.3    Muro-Cacho, C.4    Sebti, S.M.5    Gabrilovich, D.I.6
  • 44
    • 11844277698 scopus 로고    scopus 로고
    • Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease
    • P Sinha VK Clements S Ostrand-Rosenberg 2005 Reduction of myeloid-derived suppressor cells and induction of m1 macrophages facilitate the rejection of established metastatic disease Journal of Immunology 174 2 636 645 1:CAS:528:DC%2BD2MXotFSg (Pubitemid 40094255)
    • (2005) Journal of Immunology , vol.174 , Issue.2 , pp. 636-645
    • Sinha, P.1    Clements, V.K.2    Ostrand-Rosenberg, S.3
  • 45
    • 0042591427 scopus 로고    scopus 로고
    • All-trans-retinoic acid eliminates immature myeloid cells from tumor-bearing mice and improves the effect of vaccination
    • S Kusmartsev F Cheng B Yu Y Nefedova E Sotomayor R Lush, et al. 2003 All-trans-retinoic acid eliminates immature myeloid cells from tumor-bearing mice and improves the effect of vaccination Cancer Research 63 15 4441 4449 12907617 1:CAS:528:DC%2BD3sXmtFersr0%3D (Pubitemid 36951016)
    • (2003) Cancer Research , vol.63 , Issue.15 , pp. 4441-4449
    • Kusmartsev, S.1    Cheng, F.2    Yu, B.3    Nefedova, Y.4    Sotomayor, E.5    Lush, R.6    Gabrilovich, D.7
  • 46
    • 0029665697 scopus 로고    scopus 로고
    • 3 treatment of tumor bearers can stimulate immune competence and reduce tumor growth when treatment coincides with a heightened presence of natural suppressor cells
    • DOI 10.1016/0304-3835(96)04241-3
    • MR Young Y Lozano J Ihm MA Wright MM Prechel 1996 Vitamin D3 treatment of tumor bearers can stimulate immune competence and reduce tumor growth when treatment coincides with a heightened presence of natural suppressor cells Cancer Letters 104 2 153 161 8665483 1:CAS:528:DyaK28XjtlSmu7Y%3D (Pubitemid 26181005)
    • (1996) Cancer Letters , vol.104 , Issue.2 , pp. 153-161
    • Young, M.R.I.1    Lozano, Y.2    Ihm, J.3    Wright, M.A.4    Prechel, M.M.5
  • 47
    • 0026471974 scopus 로고
    • Myelopoiesis-associated immune suppressor cells in mice bearing metastatic Lewis lung carcinoma tumors: Gamma interferon plus tumor necrosis factor alpha synergistically reduces immune suppressor and tumor growth-promoting activities of bone marrow cells and diminishes tumor recurrence and metastasis
    • 1423279 1:CAS:528:DyaK3sXlsVSm
    • MR Young MA Wright 1992 Myelopoiesis-associated immune suppressor cells in mice bearing metastatic Lewis lung carcinoma tumors: gamma interferon plus tumor necrosis factor alpha synergistically reduces immune suppressor and tumor growth-promoting activities of bone marrow cells and diminishes tumor recurrence and metastasis Cancer Research 52 22 6335 6340 1423279 1:CAS:528:DyaK3sXlsVSm
    • (1992) Cancer Research , vol.52 , Issue.22 , pp. 6335-6340
    • Young, M.R.1    Wright, M.A.2
  • 48
    • 33749461167 scopus 로고    scopus 로고
    • All-trans-retinoic acid improves differentiation of myeloid cells and immune response in cancer patients
    • DOI 10.1158/0008-5472.CAN-06-1690
    • N Mirza M Fishman I Fricke M Dunn AM Neuger TJ Frost, et al. 2006 All-trans-retinoic acid improves differentiation of myeloid cells and immune response in cancer patients Cancer Research 66 18 9299 9307 10.1158/0008-5472. CAN-06-1690 16982775 1:CAS:528:DC%2BD28Xps1ahsrk%3D (Pubitemid 44521152)
    • (2006) Cancer Research , vol.66 , Issue.18 , pp. 9299-9307
    • Mirza, N.1    Fishman, M.2    Fricke, I.3    Dunn, M.4    Neuger, A.M.5    Frost, T.J.6    Lush, R.M.7    Antonia, S.8    Gabrilovich, D.I.9
  • 49
    • 77951754469 scopus 로고    scopus 로고
    • Direct and differential suppression of myeloid-derived suppressor cell subsets by sunitinib is compartmentally constrained
    • doi: 10.1158/0008-5472.CAN-09-3278
    • Ko, J. S., Rayman, P., Ireland, J., Swaidani, S., Li, G., Bunting, K. D., et al. Direct and differential suppression of myeloid-derived suppressor cell subsets by sunitinib is compartmentally constrained. Cancer Research, 70(9), 3526-3536, doi: 10.1158/0008-5472.CAN-09-3278.
    • Cancer Research , vol.70 , Issue.9 , pp. 3526-3536
    • Ko, J.S.1    Rayman, P.2    Ireland, J.3    Swaidani, S.4    Li, G.5    Bunting, K.D.6
  • 50
    • 67349133537 scopus 로고    scopus 로고
    • Gemcitabine directly inhibits myeloid derived suppressor cells in BALB/c mice bearing 4T1 mammary carcinoma and augments expansion of T cells from tumor-bearing mice
    • 10.1016/j.intimp.2009.03.015 19336265 1:CAS:528:DC%2BD1MXms1Orsrk%3D
    • HK Le L Graham E Cha JK Morales MH Manjili HD Bear 2009 Gemcitabine directly inhibits myeloid derived suppressor cells in BALB/c mice bearing 4T1 mammary carcinoma and augments expansion of T cells from tumor-bearing mice International Immunopharmacology 9 7-8 900 909 10.1016/j.intimp.2009.03.015 19336265 1:CAS:528:DC%2BD1MXms1Orsrk%3D
    • (2009) International Immunopharmacology , vol.9 , Issue.78 , pp. 900-909
    • Le, H.K.1    Graham, L.2    Cha, E.3    Morales, J.K.4    Manjili, M.H.5    Bear, H.D.6
  • 51
    • 65549141834 scopus 로고    scopus 로고
    • The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapies
    • 10.1158/0008-5472.CAN-08-4709 19276342 1:CAS:528:DC%2BD1MXjtFyqurY%3D
    • J Ozao-Choy G Ma J Kao GX Wang M Meseck M Sung, et al. 2009 The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapies Cancer Research 69 6 2514 2522 10.1158/0008-5472.CAN-08-4709 19276342 1:CAS:528:DC%2BD1MXjtFyqurY%3D
    • (2009) Cancer Research , vol.69 , Issue.6 , pp. 2514-2522
    • Ozao-Choy, J.1    Ma, G.2    Kao, J.3    Wang, G.X.4    Meseck, M.5    Sung, M.6
  • 52
    • 25144466458 scopus 로고    scopus 로고
    • + myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity
    • DOI 10.1158/1078-0432.CCR-05-0883
    • E Suzuki V Kapoor AS Jassar LR Kaiser SM Albelda 2005 Gemcitabine selectively eliminates splenic Gr-1+/CD11b+myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity Clinical Cancer Research 11 18 6713 6721 16166452 1:CAS:528:DC%2BD2MXhtVShsb3O (Pubitemid 41339014)
    • (2005) Clinical Cancer Research , vol.11 , Issue.18 , pp. 6713-6721
    • Suzuki, E.1    Kapoor, V.2    Jassar, A.S.3    Kaiser, L.R.4    Albelda, S.M.5
  • 53
    • 77951086882 scopus 로고    scopus 로고
    • 5-fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced t cell-dependent antitumor immunity
    • doi: 10.1158/0008-5472.CAN-09-3690
    • Vincent, J., Mignot, G., Chalmin, F., Ladoire, S., Bruchard, M., Chevriaux, A., et al. 5-fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced t cell-dependent antitumor immunity. Cancer Research, 70(8), 3052-3061, doi: 10.1158/0008-5472. CAN-09-3690.
    • Cancer Research , vol.70 , Issue.8 , pp. 3052-3061
    • Vincent, J.1    Mignot, G.2    Chalmin, F.3    Ladoire, S.4    Bruchard, M.5    Chevriaux, A.6
  • 54
    • 63549105681 scopus 로고    scopus 로고
    • Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients
    • 10.1158/1078-0432.CCR-08-1332 19276286 1:CAS:528:DC%2BD1MXjtF2rurY%3D
    • JS Ko AH Zea BI Rini JL Ireland P Elson P Cohen, et al. 2009 Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients Clinical Cancer Research 15 6 2148 2157 10.1158/1078-0432. CCR-08-1332 19276286 1:CAS:528:DC%2BD1MXjtF2rurY%3D
    • (2009) Clinical Cancer Research , vol.15 , Issue.6 , pp. 2148-2157
    • Ko, J.S.1    Zea, A.H.2    Rini, B.I.3    Ireland, J.L.4    Elson, P.5    Cohen, P.6
  • 55
    • 78049479930 scopus 로고    scopus 로고
    • Chemotherapy delivered after viral immunogene therapy augments antitumor efficacy via multiple immune-mediated mechanisms
    • doi: 10.1038/mt.2010.159
    • Fridlender, Z. G., Sun, J., Singhal, S., Kapoor, V., Cheng, G., Suzuki, E., et al. Chemotherapy delivered after viral immunogene therapy augments antitumor efficacy via multiple immune-mediated mechanisms. Molecular Therapy, doi: 10.1038/mt.2010.159.
    • Molecular Therapy
    • Fridlender, Z.G.1    Sun, J.2    Singhal, S.3    Kapoor, V.4    Cheng, G.5    Suzuki, E.6
  • 57
    • 76949100372 scopus 로고    scopus 로고
    • Raising the NKT cell family
    • 10.1038/ni.1841 20139988 1:CAS:528:DC%2BC3cXhs1Onsbo%3D
    • DI Godfrey S Stankovic AG Baxter 2010 Raising the NKT cell family Nature Immunology 11 3 197 206 10.1038/ni.1841 20139988 1:CAS:528:DC%2BC3cXhs1Onsbo%3D
    • (2010) Nature Immunology , vol.11 , Issue.3 , pp. 197-206
    • Godfrey, D.I.1    Stankovic, S.2    Baxter, A.G.3
  • 59
    • 0034572835 scopus 로고    scopus 로고
    • NKT cells and tumor immunity-A double-edged sword
    • 10.1038/82698 11101862 1:CAS:528:DC%2BD3cXoslyrurw%3D
    • MJ Smyth DI Godfrey 2000 NKT cells and tumor immunity-a double-edged sword Nature Immunology 1 6 459 460 10.1038/82698 11101862 1:CAS:528: DC%2BD3cXoslyrurw%3D
    • (2000) Nature Immunology , vol.1 , Issue.6 , pp. 459-460
    • Smyth, M.J.1    Godfrey, D.I.2
  • 60
    • 58149104377 scopus 로고    scopus 로고
    • Harnessing invariant NKT cells in vaccination strategies
    • 10.1038/nri2451 19079136 1:CAS:528:DC%2BD1MXpt1Cr
    • V Cerundolo JD Silk SH Masri M Salio 2009 Harnessing invariant NKT cells in vaccination strategies Nature Reviews. Immunology 9 1 28 38 10.1038/nri2451 19079136 1:CAS:528:DC%2BD1MXpt1Cr
    • (2009) Nature Reviews. Immunology , vol.9 , Issue.1 , pp. 28-38
    • Cerundolo, V.1    Silk, J.D.2    Masri, S.H.3    Salio, M.4
  • 61
    • 0037082487 scopus 로고    scopus 로고
    • + T cells and natural killer cells is essential for the antimetastatic effect of α-galactosylceramide
    • DOI 10.1182/blood.V99.4.1259
    • Smyth, M. J., Crowe, N. Y., Pellicci, D. G., Kyparissoudis, K., Kelly, J. M., Takeda, K., et al. (2002). Sequential production of interferon-gamma by nk1.1(+) t cells and natural killer cells is essential for the antimetastatic effect of alpha-galactosylceramide. Blood, 99(4), 1259-1266. (Pubitemid 34547079)
    • (2002) Blood , vol.99 , Issue.4 , pp. 1259-1266
    • Smyth, M.J.1    Crowe, N.Y.2    Pellicci, D.G.3    Kyparissoudis, K.4    Kelly, J.M.5    Takeda, K.6    Yagita, H.7    Godfrey, D.I.8
  • 62
    • 36049022618 scopus 로고    scopus 로고
    • Cross-regulation between type i and type II nkt cells in regulating tumor immunity: A new immunoregulatory axis
    • 1:CAS:528:DC%2BD2sXhtFWitrvJ
    • E Ambrosino M Terabe RC Halder J Peng S Takaku S Miyake, et al. 2007 Cross-regulation between type I and type II nkt cells in regulating tumor immunity: a new immunoregulatory axis Journal of Immunology 179 8 5126 5136 1:CAS:528:DC%2BD2sXhtFWitrvJ
    • (2007) Journal of Immunology , vol.179 , Issue.8 , pp. 5126-5136
    • Ambrosino, E.1    Terabe, M.2    Halder, R.C.3    Peng, J.4    Takaku, S.5    Miyake, S.6
  • 63
    • 0034569294 scopus 로고    scopus 로고
    • Immune suppression and skin cancer development: Regulation by NKT cells
    • 10.1038/82782 11101875 1:CAS:528:DC%2BD3cXoslyru7s%3D
    • AM Moodycliffe D Nghiem G Clydesdale SE Ullrich 2000 Immune suppression and skin cancer development: regulation by NKT cells Nature Immunology 1 6 521 525 10.1038/82782 11101875 1:CAS:528:DC%2BD3cXoslyru7s%3D
    • (2000) Nature Immunology , vol.1 , Issue.6 , pp. 521-525
    • Moodycliffe, A.M.1    Nghiem, D.2    Clydesdale, G.3    Ullrich, S.E.4
  • 64
    • 33645732440 scopus 로고    scopus 로고
    • Cd1d-restricted natural killer t cells can down-regulate tumor immunosurveillance independent of interleukin-4 receptor-signal transducer and activator of transcription 6 or transforming growth factor-beta
    • 16585215 1:CAS:528:DC%2BD28XjtVOru7c%3D
    • M Terabe C Khanna S Bose F Melchionda A Mendoza CL Mackall, et al. 2006 Cd1d-restricted natural killer t cells can down-regulate tumor immunosurveillance independent of interleukin-4 receptor-signal transducer and activator of transcription 6 or transforming growth factor-beta Cancer Research 66 7 3869 3875 16585215 1:CAS:528:DC%2BD28XjtVOru7c%3D
    • (2006) Cancer Research , vol.66 , Issue.7 , pp. 3869-3875
    • Terabe, M.1    Khanna, C.2    Bose, S.3    Melchionda, F.4    Mendoza, A.5    MacKall, C.L.6
  • 65
    • 0034569025 scopus 로고    scopus 로고
    • NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway
    • 11101874 1:CAS:528:DC%2BD3cXoslyru7o%3D
    • M Terabe S Matsui N Noben-Trauth H Chen C Watson DD Donaldson, et al. 2000 NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway Nature Immunology 1 6 515 520 11101874 1:CAS:528: DC%2BD3cXoslyru7o%3D
    • (2000) Nature Immunology , vol.1 , Issue.6 , pp. 515-520
    • Terabe, M.1    Matsui, S.2    Noben-Trauth, N.3    Chen, H.4    Watson, C.5    Donaldson, D.D.6
  • 67
    • 43349091204 scopus 로고    scopus 로고
    • Natural immunosurveillance against spontaneous, autochthonous breast cancers revealed and enhanced by blockade of IL-13-mediated negative regulation
    • 10.1007/s00262-007-0414-0 18004566 1:CAS:528:DC%2BD1cXjvFKmtL0%3D
    • JM Park M Terabe DD Donaldson G Forni JA Berzofsky 2008 Natural immunosurveillance against spontaneous, autochthonous breast cancers revealed and enhanced by blockade of IL-13-mediated negative regulation Cancer Immunology, Immunotherapy 57 6 907 912 10.1007/s00262-007-0414-0 18004566 1:CAS:528:DC%2BD1cXjvFKmtL0%3D
    • (2008) Cancer Immunology, Immunotherapy , vol.57 , Issue.6 , pp. 907-912
    • Park, J.M.1    Terabe, M.2    Donaldson, D.D.3    Forni, G.4    Berzofsky, J.A.5
  • 69
    • 0742321750 scopus 로고    scopus 로고
    • Role of IL-13 in regulation of anti-tumor immunity and tumor growth
    • DOI 10.1007/s00262-003-0445-0
    • M Terabe JM Park JA Berzofsky 2004 Role of IL-13 in regulation of anti-tumor immunity and tumor growth Cancer Immunology, Immunotherapy 53 2 79 85 14610620 1:CAS:528:DC%2BD3sXpvVektr8%3D (Pubitemid 38161213)
    • (2004) Cancer Immunology, Immunotherapy , vol.53 , Issue.2 , pp. 79-85
    • Terabe, M.1    Park, J.M.2    Berzofsky, J.A.3
  • 70
  • 71
    • 77953437752 scopus 로고    scopus 로고
    • Chemokine-chemokine receptors in cancer immunotherapy
    • 10.2217/1750743X.1.1.109 20635978 1:CAS:528:DC%2BD1MXhtVygsrrE
    • TJ Stewart MJ Smyth 2009 Chemokine-chemokine receptors in cancer immunotherapy Immunotherapy 1 1 109 127 10.2217/1750743X.1.1.109 20635978 1:CAS:528:DC%2BD1MXhtVygsrrE
    • (2009) Immunotherapy , vol.1 , Issue.1 , pp. 109-127
    • Stewart, T.J.1    Smyth, M.J.2
  • 72
    • 0036372440 scopus 로고    scopus 로고
    • Transforming growth factor-β in T-cell biology
    • L Gorelik RA Flavell 2002 Transforming growth factor-beta in T-cell biology Nature Reviews. Immunology 2 1 46 53 10.1038/nri704 11905837 1:CAS:528:DC%2BD38XhslyitL8%3D (Pubitemid 37328775)
    • (2002) Nature Reviews Immunology , vol.2 , Issue.1 , pp. 46-53
    • Gorelik, L.1    Flavell, R.A.2
  • 73
    • 0031944290 scopus 로고    scopus 로고
    • Regulation of immune responses by TGF-β
    • DOI 10.1146/annurev.immunol.16.1.137
    • JJ Letterio AB Roberts 1998 Regulation of immune responses by TGF-beta Annual Review of Immunology 16 137 161 10.1146/annurev.immunol.16.1.137 9597127 1:CAS:528:DyaK1cXislyhsrk%3D (Pubitemid 28183362)
    • (1998) Annual Review of Immunology , vol.16 , pp. 137-161
    • Letterio, J.J.1    Roberts, A.B.2
  • 74
    • 48449086316 scopus 로고    scopus 로고
    • TGF-beta: A master of all T cell trades
    • 10.1016/j.cell.2008.07.025 18692464 1:CAS:528:DC%2BD1cXhtVSis77N
    • MO Li RA Flavell 2008 TGF-beta: a master of all T cell trades Cell 134 3 392 404 10.1016/j.cell.2008.07.025 18692464 1:CAS:528:DC%2BD1cXhtVSis77N
    • (2008) Cell , vol.134 , Issue.3 , pp. 392-404
    • Li, M.O.1    Flavell, R.A.2
  • 75
    • 0030456368 scopus 로고    scopus 로고
    • A role for endogenous transforming growth factor β1 in Langerhans cell biology: The skin of transforming growth factor β1 null mice is devoid of epidermal Langerhans cells
    • DOI 10.1084/jem.184.6.2417
    • TA Borkowski JJ Letterio AG Farr MC Udey 1996 A role for endogenous transforming growth factor beta 1 in langerhans cell biology: the skin of transforming growth factor beta 1 null mice is devoid of epidermal langerhans cells The Journal of Experimental Medicine 184 6 2417 2422 8976197 1:CAS:528:DyaK2sXjsFCr (Pubitemid 27023742)
    • (1996) Journal of Experimental Medicine , vol.184 , Issue.6 , pp. 2417-2422
    • Borkowski, T.A.1    Letterio, J.J.2    Farr, A.G.3    Udey, M.C.4
  • 77
    • 33745515023 scopus 로고    scopus 로고
    • Tumour microenvironment - TGFΒ: The molecular Jekyll and Hyde of cancer
    • DOI 10.1038/nrc1926, PII N1926
    • B Bierie HL Moses 2006 Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer Nature Reviews. Cancer 6 7 506 520 10.1038/nrc1926 16794634 1:CAS:528:DC%2BD28XmtFegsr4%3D (Pubitemid 43980540)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.7 , pp. 506-520
    • Bierie, B.1    Moses, H.L.2
  • 78
    • 77449107574 scopus 로고    scopus 로고
    • Blockade of tgf-beta enhances tumor vaccine efficacy mediated by cd8(+) t cells
    • doi: 10.1002/ijc.24961
    • Takaku, S., Terabe, M., Ambrosino, E., Peng, J., Lonning, S., McPherson, J. M., et al. Blockade of tgf-beta enhances tumor vaccine efficacy mediated by cd8(+) t cells. International Journal of Cancer, 126(7), 1666-1674, doi: 10.1002/ijc.24961.
    • International Journal of Cancer , vol.126 , Issue.7 , pp. 1666-1674
    • Takaku, S.1    Terabe, M.2    Ambrosino, E.3    Peng, J.4    Lonning, S.5    McPherson, J.M.6
  • 79
    • 70350738483 scopus 로고    scopus 로고
    • Synergistic enhancement of CD8+ T cell-mediated tumor vaccine efficacy by an anti-transforming growth factor-beta monoclonal antibody
    • 10.1158/1078-0432.CCR-09-1066 19861451 1:CAS:528:DC%2BD1MXhtlCjsrbM
    • M Terabe E Ambrosino S Takaku JJ O'Konek D Venzon S Lonning, et al. 2009 Synergistic enhancement of CD8+ T cell-mediated tumor vaccine efficacy by an anti-transforming growth factor-beta monoclonal antibody Clinical Cancer Research 15 21 6560 6569 10.1158/1078-0432.CCR-09-1066 19861451 1:CAS:528:DC%2BD1MXhtlCjsrbM
    • (2009) Clinical Cancer Research , vol.15 , Issue.21 , pp. 6560-6569
    • Terabe, M.1    Ambrosino, E.2    Takaku, S.3    O'Konek, J.J.4    Venzon, D.5    Lonning, S.6
  • 80
    • 70350708139 scopus 로고    scopus 로고
    • Systemic inhibition of transforming growth factor-beta in glioma-bearing mice improves the therapeutic efficacy of glioma-associated antigen peptide vaccines
    • 10.1158/1078-0432.CCR-09-1067 19861464 1:CAS:528:DC%2BD1MXhtlCjsrnF
    • R Ueda M Fujita X Zhu K Sasaki ER Kastenhuber G Kohanbash, et al. 2009 Systemic inhibition of transforming growth factor-beta in glioma-bearing mice improves the therapeutic efficacy of glioma-associated antigen peptide vaccines Clinical Cancer Research 15 21 6551 6559 10.1158/1078-0432.CCR-09-1067 19861464 1:CAS:528:DC%2BD1MXhtlCjsrnF
    • (2009) Clinical Cancer Research , vol.15 , Issue.21 , pp. 6551-6559
    • Ueda, R.1    Fujita, M.2    Zhu, X.3    Sasaki, K.4    Kastenhuber, E.R.5    Kohanbash, G.6
  • 81
    • 72049091524 scopus 로고    scopus 로고
    • Targeting the transforming growth factor-beta signaling pathway in human cancer
    • doi: 10.1517/13543780903382609
    • Nagaraj, N. S., & Datta, P. K. Targeting the transforming growth factor-beta signaling pathway in human cancer. Expert Opinion on Investigational Drugs, 19(1), 77-91, doi: 10.1517/13543780903382609.
    • Expert Opinion on Investigational Drugs , vol.19 , Issue.1 , pp. 77-91
    • Nagaraj, N.S.1    Datta, P.K.2
  • 83
    • 71949123241 scopus 로고    scopus 로고
    • Treatment of malignant gliomas with TGF-beta2 antisense oligonucleotides
    • 10.1586/era.09.138 19895249 1:CAS:528:DC%2BD1MXhtl2rsbrL
    • P Hau P Jachimczak U Bogdahn 2009 Treatment of malignant gliomas with TGF-beta2 antisense oligonucleotides Expert Review of Anticancer Therapy 9 11 1663 1674 10.1586/era.09.138 19895249 1:CAS:528:DC%2BD1MXhtl2rsbrL
    • (2009) Expert Review of Anticancer Therapy , vol.9 , Issue.11 , pp. 1663-1674
    • Hau, P.1    Jachimczak, P.2    Bogdahn, U.3
  • 85
    • 67651091694 scopus 로고    scopus 로고
    • Phase II trial of Belagenpumatucel-l, a TGF-beta2 antisense gene modified allogeneic tumor vaccine in advanced non small cell lung cancer (NSCLC) patients
    • 10.1038/cgt.2009.15 19287371 1:CAS:528:DC%2BD1MXjtFCju7o%3D
    • J Nemunaitis M Nemunaitis N Senzer P Snitz C Bedell P Kumar, et al. 2009 Phase II trial of Belagenpumatucel-l, a TGF-beta2 antisense gene modified allogeneic tumor vaccine in advanced non small cell lung cancer (NSCLC) patients Cancer Gene Therapy 16 8 620 624 10.1038/cgt.2009.15 19287371 1:CAS:528:DC%2BD1MXjtFCju7o%3D
    • (2009) Cancer Gene Therapy , vol.16 , Issue.8 , pp. 620-624
    • Nemunaitis, J.1    Nemunaitis, M.2    Senzer, N.3    Snitz, P.4    Bedell, C.5    Kumar, P.6
  • 86
    • 9644302458 scopus 로고    scopus 로고
    • Interleukin-10 in viral diseases and cancer: Exiting the labyrinth?
    • DOI 10.1111/j.0105-2896.2004.00216.x
    • AP Vicari G Trinchieri 2004 Interleukin-10 in viral diseases and cancer: exiting the labyrinth? Immunological Reviews 202 223 236 10.1111/j.0105-2896. 2004.00216.x 15546396 1:CAS:528:DC%2BD2MXhs1OhtA%3D%3D (Pubitemid 39576915)
    • (2004) Immunological Reviews , vol.202 , pp. 223-236
    • Vicari, A.P.1    Trinchieri, G.2
  • 87
    • 77949275202 scopus 로고    scopus 로고
    • Use of anti-vegf adjuvant therapy in cancer: Challenges and rationale
    • doi: 10.1016/j.molmed.2010.01.004
    • Bagri, A., Kouros-Mehr, H., Leong, K. G., & Plowman, G. D. Use of anti-vegf adjuvant therapy in cancer: Challenges and rationale. Trends in Molecular Medicine, 16(3), 122-132, doi: 10.1016/j.molmed.2010.01.004.
    • Trends in Molecular Medicine , vol.16 , Issue.3 , pp. 122-132
    • Bagri, A.1    Kouros-Mehr, H.2    Leong, K.G.3    Plowman, G.D.4
  • 88
    • 70350558753 scopus 로고    scopus 로고
    • Physiology and therapeutics of vascular endothelial growth factor in tumor immunosuppression
    • 19689297 1:CAS:528:DC%2BD1MXhtVWkt7nI
    • B Johnson T Osada T Clay H Lyerly M Morse 2009 Physiology and therapeutics of vascular endothelial growth factor in tumor immunosuppression Current Molecular Medicine 9 6 702 707 19689297 1:CAS:528:DC%2BD1MXhtVWkt7nI
    • (2009) Current Molecular Medicine , vol.9 , Issue.6 , pp. 702-707
    • Johnson, B.1    Osada, T.2    Clay, T.3    Lyerly, H.4    Morse, M.5
  • 89
    • 0032741283 scopus 로고    scopus 로고
    • Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function
    • DI Gabrilovich T Ishida S Nadaf JE Ohm DP Carbone 1999 Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function Clinical Cancer Research 5 10 2963 2970 10537366 1:CAS:528:DyaK1MXntlGlu7w%3D (Pubitemid 29493976)
    • (1999) Clinical Cancer Research , vol.5 , Issue.10 , pp. 2963-2970
    • Gabrilovich, D.I.1    Ishida, T.2    Nadaf, S.3    Ohm, J.E.4    Carbone, D.P.5
  • 90
    • 63949087054 scopus 로고    scopus 로고
    • Influence of bevacizumab, sunitinib and sorafenib as single agents or in combination on the inhibitory effects of VEGF on human dendritic cell differentiation from monocytes
    • 10.1038/sj.bjc.6604965 19277038 1:CAS:528:DC%2BD1MXktVGktro%3D
    • C Alfaro N Suarez A Gonzalez S Solano L Erro J Dubrot, et al. 2009 Influence of bevacizumab, sunitinib and sorafenib as single agents or in combination on the inhibitory effects of VEGF on human dendritic cell differentiation from monocytes British Journal of Cancer 100 7 1111 1119 10.1038/sj.bjc.6604965 19277038 1:CAS:528:DC%2BD1MXktVGktro%3D
    • (2009) British Journal of Cancer , vol.100 , Issue.7 , pp. 1111-1119
    • Alfaro, C.1    Suarez, N.2    Gonzalez, A.3    Solano, S.4    Erro, L.5    Dubrot, J.6
  • 91
    • 33845343558 scopus 로고    scopus 로고
    • Vascular endothelial growth factor blockade reduces intratumoral regulatory T cells and enhances the efficacy of a GM-CSF-secreting cancer immunotherapy
    • DOI 10.1158/1078-0432.CCR-06-1558
    • B Li AS Lalani TC Harding B Luan K Koprivnikar G Huan Tu, et al. 2006 Vascular endothelial growth factor blockade reduces intratumoral regulatory T cells and enhances the efficacy of a GM-CSF-secreting cancer immunotherapy Clinical Cancer Research 12 22 6808 6816 10.1158/1078-0432.CCR-06-1558 17121902 1:CAS:528:DC%2BD28Xht1elsLzE (Pubitemid 44876851)
    • (2006) Clinical Cancer Research , vol.12 , Issue.22 , pp. 6808-6816
    • Li, B.1    Lalani, A.S.2    Harding, T.C.3    Luan, B.4    Koprivnikar, K.5    Guang, H.T.6    Prell, R.7    VanRoey, M.J.8    Simmons, A.D.9    Jooss, K.10
  • 92
    • 44249093051 scopus 로고    scopus 로고
    • The effect of anti-VEGF therapy on immature myeloid cell and dendritic cells in cancer patients
    • 10.1007/s00262-007-0441-x 18193223 1:CAS:528:DC%2BD1cXmt1OisLY%3D
    • T Osada G Chong R Tansik T Hong N Spector R Kumar, et al. 2008 The effect of anti-VEGF therapy on immature myeloid cell and dendritic cells in cancer patients Cancer Immunology, Immunotherapy 57 8 1115 1124 10.1007/s00262-007- 0441-x 18193223 1:CAS:528:DC%2BD1cXmt1OisLY%3D
    • (2008) Cancer Immunology, Immunotherapy , vol.57 , Issue.8 , pp. 1115-1124
    • Osada, T.1    Chong, G.2    Tansik, R.3    Hong, T.4    Spector, N.5    Kumar, R.6
  • 93
    • 33745304967 scopus 로고    scopus 로고
    • Combination immunotherapy with prostatic acid phosphatase pulsed antigen-presenting cells (provenge) plus bevacizumab in patients with serologic progression of prostate cancer after definitive local therapy
    • DOI 10.1002/cncr.21956
    • BI Rini V Weinberg L Fong S Conry RM Hershberg EJ Small 2006 Combination immunotherapy with prostatic acid phosphatase pulsed antigen-presenting cells (provenge) plus bevacizumab in patients with serologic progression of prostate cancer after definitive local therapy Cancer 107 1 67 74 10.1002/cncr.21956 16736512 1:CAS:528:DC%2BD28XntVymu70%3D (Pubitemid 43939032)
    • (2006) Cancer , vol.107 , Issue.1 , pp. 67-74
    • Rini, B.I.1    Weinberg, V.2    Fong, L.3    Conry, S.4    Hershberg, R.M.5    Small, E.J.6
  • 94
    • 2342526003 scopus 로고    scopus 로고
    • CCL2 (monocyte chemoattractant protein-1) and cancer
    • DOI 10.1016/j.semcancer.2003.10.009, PII S1044579X03000956
    • I Conti BJ Rollins 2004 CCL2 (monocyte chemoattractant protein-1) and cancer Seminars in Cancer Biology 14 3 149 154 15246049 1:CAS:528: DC%2BD2cXjvVemsb4%3D (Pubitemid 38586739)
    • (2004) Seminars in Cancer Biology , vol.14 , Issue.3 , pp. 149-154
    • Conti, I.1    Rollins, B.J.2
  • 96
    • 34648843603 scopus 로고    scopus 로고
    • Recombined CC chemokine ligand 2 into B16 cells induces production of Th2-dominanted cytokines and inhibits melanoma metastasis
    • DOI 10.1016/j.imlet.2007.07.004, PII S0165247807001472
    • K Hu J Xiong K Ji H Sun J Wang H Liu 2007 Recombined CC chemokine ligand 2 into B16 cells induces production of th2-dominant [correction of dominanted] cytokines and inhibits melanoma metastasis Immunology Letters 113 1 19 28 10.1016/j.imlet.2007.07.004 17868906 1:CAS:528:DC%2BD2sXhtFSnu73L (Pubitemid 47464614)
    • (2007) Immunology Letters , vol.113 , Issue.1 , pp. 19-28
    • Hu, K.1    Xiong, J.2    Ji, K.3    Sun, H.4    Wang, J.5    Liu, H.6
  • 97
    • 0030780374 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein inhibits the generation of tumor- reactive T cells
    • L Peng S Shu JC Krauss 1997 Monocyte chemoattractant protein inhibits the generation of tumor-reactive t cells Cancer Research 57 21 4849 4854 9354448 1:CAS:528:DyaK2sXnt12nsr8%3D (Pubitemid 27468993)
    • (1997) Cancer Research , vol.57 , Issue.21 , pp. 4849-4854
    • Peng, L.1    Shu, S.2    Krauss, J.C.3
  • 98
    • 0033903714 scopus 로고    scopus 로고
    • Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer
    • T Ueno M Toi H Saji M Muta H Bando K Kuroi, et al. 2000 Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer Clinical Cancer Research 6 8 3282 3289 10955814 1:CAS:528:DC%2BD3cXmsVOmt7c%3D (Pubitemid 30637758)
    • (2000) Clinical Cancer Research , vol.6 , Issue.8 , pp. 3282-3289
    • Ueno, T.1    Toi, M.2    Saji, H.3    Muta, M.4    Bando, H.5    Kuroi, K.6    Koike, M.7    Inadera, H.8    Matsushima, K.9
  • 99
    • 35748975652 scopus 로고    scopus 로고
    • Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy
    • DOI 10.1007/s00262-007-0336-x
    • JT Jordan W Sun SF Hussain G DeAngulo SS Prabhu AB Heimberger 2008 Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy Cancer Immunology, Immunotherapy 57 1 123 131 10.1007/s00262-007-0336-x 17522861 1:CAS:528:DC%2BD2sXht1aqs77P (Pubitemid 350043644)
    • (2008) Cancer Immunology, Immunotherapy , vol.57 , Issue.1 , pp. 123-131
    • Jordan, J.T.1    Sun, W.2    Hussain, S.F.3    DeAngulo, G.4    Prabhu, S.S.5    Heimberger, A.B.6
  • 100
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • JW Pollard 2004 Tumour-educated macrophages promote tumour progression and metastasis Nature Reviews. Cancer 4 1 71 78 10.1038/nrc1256 nrc1256 14708027 1:CAS:528:DC%2BD2cXos12qtA%3D%3D (Pubitemid 38082155)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.1 , pp. 71-78
    • Pollard, J.W.1
  • 101
    • 35148852659 scopus 로고    scopus 로고
    • Targeting CCL2 with systemic delivery of neutralizing antibodies induces prostate cancer tumor regression in vivo
    • DOI 10.1158/0008-5472.CAN-07-1286
    • RD Loberg C Ying M Craig LL Day E Sargent C Neeley, et al. 2007 Targeting CCL2 with systemic delivery of neutralizing antibodies induces prostate cancer tumor regression in vivo Cancer Research 67 19 9417 9424 17909051 1:CAS:528:DC%2BD2sXhtFSnurrE (Pubitemid 47535932)
    • (2007) Cancer Research , vol.67 , Issue.19 , pp. 9417-9424
    • Loberg, R.D.1    Ying, C.2    Craig, M.3    Day, L.L.4    Sargent, E.5    Neeley, C.6    Wojno, K.7    Snyder, L.A.8    Yan, L.9    Pienta, K.J.10
  • 102
    • 34547184682 scopus 로고    scopus 로고
    • CCL2 as an important mediator of prostate cancer growth in vivo through the regulation of macrophage infiltration
    • DOI 10.1593/neo.07307
    • RD Loberg C Ying M Craig L Yan LA Snyder KJ Pienta 2007 CCL2 as an important mediator of prostate cancer growth in vivo through the regulation of macrophage infiltration Neoplasia 9 7 556 562 17710158 1:CAS:528: DC%2BD2sXptlKrtbY%3D (Pubitemid 47121829)
    • (2007) Neoplasia , vol.9 , Issue.7 , pp. 556-562
    • Loberg, R.D.1    Ying, C.2    Craig, M.3    Yan, L.4    Snyder, L.A.5    Pienta, K.J.6
  • 103
    • 75149141334 scopus 로고    scopus 로고
    • Ccl2 blockade augments cancer immunotherapy
    • doi: 10.1158/0008-5472.CAN-09-2326
    • Fridlender, Z. G., Buchlis, G., Kapoor, V., Cheng, G., Sun, J., Singhal, S., et al. Ccl2 blockade augments cancer immunotherapy. Cancer Research, 70(1), 109-118, doi: 10.1158/0008-5472.CAN-09-2326.
    • Cancer Research , vol.70 , Issue.1 , pp. 109-118
    • Fridlender, Z.G.1    Buchlis, G.2    Kapoor, V.3    Cheng, G.4    Sun, J.5    Singhal, S.6
  • 104
    • 0036231207 scopus 로고    scopus 로고
    • Immune privilege and FasL: Two ways to inactivate effector cytotoxic T lymphocytes by FasL-expressing cells
    • DOI 10.1046/j.1365-2567.2002.01380.x
    • JH Li D Rosen P Sondel G Berke 2002 Immune privilege and FasL: two ways to inactivate effector cytotoxic t lymphocytes by FasL-expressing cells Immunology 105 3 267 277 11918688 1:CAS:528:DC%2BD38Xit1GrsLo%3D (Pubitemid 34304403)
    • (2002) Immunology , vol.105 , Issue.3 , pp. 267-277
    • Li, J.-H.1    Rosen, D.2    Sondel, P.3    Berke, G.4
  • 105
    • 0042389785 scopus 로고    scopus 로고
    • T cell anergy
    • DOI 10.1146/annurev.immunol.21.120601.141110
    • RH Schwartz 2003 T cell anergy Annual Review of Immunology 21 305 334 10.1146/annurev.immunol.21.120601.141110 12471050 1:CAS:528:DC%2BD3sXjtF2isrs%3D (Pubitemid 37174534)
    • (2003) Annual Review of Immunology , vol.21 , pp. 305-334
    • Schwartz, R.H.1
  • 106
    • 0036897080 scopus 로고    scopus 로고
    • Vaccine-based therapy directed against carcinoembryonic antigen demonstrates antitumor activity on spontaneous intestinal tumors in the absence of autoimmunity
    • JW Greiner H Zeytin MR Anver J Schlom 2002 Vaccine-based therapy directed against carcinoembryonic antigen demonstrates antitumor activity on spontaneous intestinal tumors in the absence of autoimmunity Cancer Research 62 23 6944 6951 12460911 1:CAS:528:DC%2BD38XpsVahsLk%3D (Pubitemid 35424085)
    • (2002) Cancer Research , vol.62 , Issue.23 , pp. 6944-6951
    • Greiner, J.W.1    Zeytin, H.2    Anver, M.R.3    Schlom, J.4
  • 108
    • 20044364936 scopus 로고    scopus 로고
    • Phase I study of sequential vaccinations with fowlpox-CEA(6D)-TRICOM alone and sequentially with vaccinia-CEA(6D)-TRICOM, with and without granulocyte-macrophage colony-stimulating factor, in patients with carcinoembryonic antigen-expressing carcinomas
    • DOI 10.1200/JCO.2005.10.206
    • JL Marshall JL Gulley PM Arlen PK Beetham KY Tsang R Slack, et al. 2005 Phase i study of sequential vaccinations with fowlpox-CEA(6D)-TRICOM alone and sequentially with vaccinia-CEA(6D)-TRICOM, with and without granulocyte- macrophage colony-stimulating factor, in patients with carcinoembryonic antigen-expressing carcinomas Journal of Clinical Oncology 23 4 720 731 10.1200/JCO.2005.10.206 15613691 1:CAS:528:DC%2BD2MXitVKisbY%3D (Pubitemid 46224171)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.4 , pp. 720-731
    • Marshall, J.L.1    Gulley, J.L.2    Arlen, P.M.3    Beetham, P.K.4    Tsang, K.-Y.5    Slack, R.6    Hodge, J.W.7    Doren, S.8    Grosenbach, D.W.9    Hwang, J.10    Fox, E.11    Odogwu, L.12    Park, S.13    Panicali, D.14    Schlom, J.15
  • 109
    • 41149109745 scopus 로고    scopus 로고
    • Signaling defects in anti-tumor T cells
    • DOI 10.1111/j.1600-065X.2008.00606.x
    • AB Frey N Monu 2008 Signaling defects in anti-tumor T cells Immunological Reviews 222 192 205 10.1111/j.1600-065X.2008.00606.x 18364003 1:CAS:528:DC%2BD1cXlsFejt7w%3D (Pubitemid 351430368)
    • (2008) Immunological Reviews , vol.222 , Issue.1 , pp. 192-205
    • Frey, A.B.1    Monu, N.2
  • 110
    • 76749151403 scopus 로고    scopus 로고
    • Immune responses to malignancies
    • doi: 10.1016/j.jaci.2009.09.045
    • Whiteside, T. L. Immune responses to malignancies. Journal of Allergy and Clinical Immunology, 125(2 Suppl 2), S272-S283, doi: 10.1016/j.jaci.2009.09. 045.
    • Journal of Allergy and Clinical Immunology , vol.125 , Issue.2 SUPPL. 2
    • Whiteside, T.L.1
  • 111
    • 0036301503 scopus 로고    scopus 로고
    • CTLA-4: New insights into its biological function and use in tumor immunotherapy
    • DOI 10.1038/ni0702-611
    • JG Egen MS Kuhns JP Allison 2002 CTLA-4: new insights into its biological function and use in tumor immunotherapy Nature Immunology 3 7 611 618 12087419 1:CAS:528:DC%2BD38Xksl2mtbs%3D (Pubitemid 34752469)
    • (2002) Nature Immunology , vol.3 , Issue.7 , pp. 611-618
    • Egen, J.G.1    Kuhns, M.S.2    Allison, J.P.3
  • 112
    • 13544271675 scopus 로고    scopus 로고
    • + T cells
    • DOI 10.1182/blood-2004-06-2089
    • A Boasso JP Herbeuval AW Hardy C Winkler GM Shearer 2005 Regulation of indoleamine 2, 3-dioxygenase and tryptophanyl-tRNA-synthetase by CTLA-4-Fc in human CD4+ T cells Blood 105 4 1574 1581 10.1182/blood-2004-06-2089 15466932 1:CAS:528:DC%2BD2MXhsVChtbs%3D (Pubitemid 40223677)
    • (2005) Blood , vol.105 , Issue.4 , pp. 1574-1581
    • Boasso, A.1    Herbeuval, J.-P.2    Hardy, A.W.3    Winkler, C.4    Shearer, G.M.5
  • 113
    • 77954938867 scopus 로고    scopus 로고
    • Enhanced tumor eradication by combining ctla-4 or pd-1 blockade with cpg therapy
    • doi: 10.1097/CJI.0b013e3181c01fcb
    • Mangsbo, S. M., Sandin, L. C., Anger, K., Korman, A. J., Loskog, A., & Totterman, T. H. Enhanced tumor eradication by combining ctla-4 or pd-1 blockade with cpg therapy. Journal of Immunotherapy, 33(3), 225-235, doi: 10.1097/CJI.0b013e3181c01fcb.
    • Journal of Immunotherapy , vol.33 , Issue.3 , pp. 225-235
    • Mangsbo, S.M.1    Sandin, L.C.2    Anger, K.3    Korman, A.J.4    Loskog, A.5    Totterman, T.H.6
  • 114
    • 77954704783 scopus 로고    scopus 로고
    • Combination therapy of established tumors by antibodies targeting immune activating and suppressing molecules
    • doi: 10.4049/jimmunol.0903033
    • Takeda, K., Kojima, Y., Uno, T., Hayakawa, Y., Teng, M. W., Yoshizawa, H., et al. Combination therapy of established tumors by antibodies targeting immune activating and suppressing molecules. Journal of Immunology, 184(10), 5493-5501, doi: 10.4049/jimmunol.0903033.
    • Journal of Immunology , vol.184 , Issue.10 , pp. 5493-5501
    • Takeda, K.1    Kojima, Y.2    Uno, T.3    Hayakawa, Y.4    Teng, M.W.5    Yoshizawa, H.6
  • 115
    • 67651146461 scopus 로고    scopus 로고
    • Recent advances using anti-CTLA-4 for the treatment of melanoma
    • 10.1097/PPO.0b013e3181a7450f 1:CAS:528:DC%2BD1MXot12rsL8%3D
    • AA Sarnaik JS Weber 2009 Recent advances using anti-CTLA-4 for the treatment of melanoma Cancer Journal 15 3 169 173 10.1097/PPO.0b013e3181a7450f 1:CAS:528:DC%2BD1MXot12rsL8%3D
    • (2009) Cancer Journal , vol.15 , Issue.3 , pp. 169-173
    • Sarnaik, A.A.1    Weber, J.S.2
  • 116
    • 75749151759 scopus 로고    scopus 로고
    • Novel immunotherapies as potential therapeutic partners for traditional or targeted agents: Cytotoxic t-lymphocyte antigen-4 blockade in advanced melanoma
    • doi: 10.1097/CMR.0b013e328333bbc8
    • Agarwala, S. S. Novel immunotherapies as potential therapeutic partners for traditional or targeted agents: Cytotoxic t-lymphocyte antigen-4 blockade in advanced melanoma. Melanoma Research, 20(1), 1-10, doi: 10.1097/CMR. 0b013e328333bbc8.
    • Melanoma Research , vol.20 , Issue.1 , pp. 1-10
    • Agarwala, S.S.1
  • 117
    • 77953464932 scopus 로고    scopus 로고
    • Targeting cytotoxic t-lymphocyte antigen 4 in immunotherapies for melanoma and other cancers
    • doi: 10.2217/imt.10.21
    • Page, D. B., Yuan, J., & Wolchok, J. D. Targeting cytotoxic t-lymphocyte antigen 4 in immunotherapies for melanoma and other cancers. Immunotherapy, 2(3), 367-379, doi: 10.2217/imt.10.21.
    • Immunotherapy , vol.2 , Issue.3 , pp. 367-379
    • Page, D.B.1    Yuan, J.2    Wolchok, J.D.3
  • 118
    • 33749428422 scopus 로고    scopus 로고
    • The clinical utility of cytotoxic T lymphocyte antigen 4 abrogation by human antibodies
    • DOI 10.1097/01.cmr.0000232292.06785.a3, PII 0000839020061000000002
    • JS Weber 2006 The clinical utility of cytotoxic T lymphocyte antigen 4 abrogation by human antibodies Melanoma Research 16 5 379 383 10.1097/01.cmr.0000232292.06785.a3 17013086 1:CAS:528:DC%2BD28XhtVWntr7O (Pubitemid 44511217)
    • (2006) Melanoma Research , vol.16 , Issue.5 , pp. 379-383
    • Weber, J.S.1
  • 119
    • 18544380239 scopus 로고    scopus 로고
    • Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
    • 1:CAS:528:DC%2BD38Xls12msLo%3D
    • H Dong SE Strome DR Salomao H Tamura F Hirano DB Flies, et al. 2002 Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion Natural Medicines 8 8 793 800 1:CAS:528:DC%2BD38Xls12msLo%3D
    • (2002) Natural Medicines , vol.8 , Issue.8 , pp. 793-800
    • Dong, H.1    Strome, S.E.2    Salomao, D.R.3    Tamura, H.4    Hirano, F.5    Flies, D.B.6
  • 120
    • 66949111877 scopus 로고    scopus 로고
    • PD-1 is a regulator of NY-ESO-1-specific CD8+ T cell expansion in melanoma patients
    • 10.4049/jimmunol.0803245 1:CAS:528:DC%2BD1MXkslKju7c%3D
    • J Fourcade P Kudela Z Sun H Shen SR Land D Lenzner, et al. 2009 PD-1 is a regulator of NY-ESO-1-specific CD8+ T cell expansion in melanoma patients Journal of Immunology 182 9 5240 5249 10.4049/jimmunol.0803245 1:CAS:528:DC%2BD1MXkslKju7c%3D
    • (2009) Journal of Immunology , vol.182 , Issue.9 , pp. 5240-5249
    • Fourcade, J.1    Kudela, P.2    Sun, Z.3    Shen, H.4    Land, S.R.5    Lenzner, D.6
  • 122
    • 77957723967 scopus 로고    scopus 로고
    • Upregulation of tim-3 and pd-1 expression is associated with tumor antigen-specific cd8+ t cell dysfunction in melanoma patients
    • doi: 10.1084/jem.20100637
    • Fourcade, J., Sun, Z., Benallaoua, M., Guillaume, P., Luescher, I. F., Sander, C., et al. Upregulation of tim-3 and pd-1 expression is associated with tumor antigen-specific cd8+ t cell dysfunction in melanoma patients. Journal of Experimental Medicine, doi: 10.1084/jem.20100637.
    • Journal of Experimental Medicine
    • Fourcade, J.1    Sun, Z.2    Benallaoua, M.3    Guillaume, P.4    Luescher, I.F.5    Sander, C.6
  • 123
    • 21344456553 scopus 로고    scopus 로고
    • Role of B7-H1 and B7-H4 molecules in down-regulating effector phase of T-cell immunity: Novel cancer escaping mechanisms
    • M Ichikawa L Chen 2005 Role of B7-H1 and B7-H4 molecules in down-regulating effector phase of T-cell immunity: novel cancer escaping mechanisms Frontiers in Bioscience 10 2856 2860 15970540 1:CAS:528: DC%2BD2MXntFGisbg%3D (Pubitemid 40910526)
    • (2005) Frontiers in Bioscience , vol.10 , Issue.SUPPL. 3 , pp. 2856-2860
    • Ichikawa, M.1    Chen, L.2
  • 124
    • 69749106159 scopus 로고    scopus 로고
    • PD1 blockade reverses the suppression of melanoma antigen-specific CTL by CD4+ CD25(hi) regulatory t cells
    • 10.1093/intimm/dxp072 19651643 1:CAS:528:DC%2BD1MXhtVKntbvK
    • W Wang R Lau D Yu W Zhu A Korman J Weber 2009 PD1 blockade reverses the suppression of melanoma antigen-specific CTL by CD4+ CD25(hi) regulatory t cells International Immunology 21 9 1065 1077 10.1093/intimm/dxp072 19651643 1:CAS:528:DC%2BD1MXhtVKntbvK
    • (2009) International Immunology , vol.21 , Issue.9 , pp. 1065-1077
    • Wang, W.1    Lau, R.2    Yu, D.3    Zhu, W.4    Korman, A.5    Weber, J.6
  • 126
    • 77954899030 scopus 로고    scopus 로고
    • Phase i study of single-agent anti-programmed death-1 (mdx-1106) in
    • doi: 10.1200/JCO.2009.26.7609
    • Brahmer, J. R., Drake, C. G., Wollner, I., Powderly, J. D., Picus, J., Sharfman, W. H., et al. Phase i study of single-agent anti-programmed death-1 (mdx-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. Journal of Clinical Oncology, 28(19), 3167-3175, doi: 10.1200/JCO.2009.26.7609.
    • Journal of Clinical Oncology , vol.28 , Issue.19 , pp. 3167-3175
    • Brahmer, J.R.1    Drake, C.G.2    Wollner, I.3    Powderly, J.D.4    Picus, J.5    Sharfman, W.H.6
  • 127
    • 34249827735 scopus 로고    scopus 로고
    • Amino acids and immune function
    • DOI 10.1017/S000711450769936X, PII S000711450769936X
    • P Li YL Yin D Li SW Kim G Wu 2007 Amino acids and immune function The British Journal of Nutrition 98 2 237 252 10.1017/S000711450769936X 17403271 1:CAS:528:DC%2BD2sXpsFentrg%3D (Pubitemid 47091364)
    • (2007) British Journal of Nutrition , vol.98 , Issue.2 , pp. 237-252
    • Li, P.1    Yin, Y.-L.2    Li, D.3    Kim, W.S.4    Wu, G.5
  • 128
    • 23444456772 scopus 로고    scopus 로고
    • Regulation of immune responses by L-arginine metabolism
    • DOI 10.1038/nri1668
    • V Bronte P Zanovello 2005 Regulation of immune responses by l-arginine metabolism Nature Reviews. Immunology 5 8 641 654 16056256 1:CAS:528: DC%2BD2MXmvVClsLc%3D (Pubitemid 41113195)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.8 , pp. 641-654
    • Bronte, V.1    Zanovello, P.2
  • 129
    • 34247613216 scopus 로고    scopus 로고
    • Nitric oxide, a double edged sword in cancer biology: Searching for therapeutic opportunities
    • DOI 10.1002/med.20092
    • S Mocellin V Bronte D Nitti 2007 Nitric oxide, a double edged sword in cancer biology: searching for therapeutic opportunities Medicinal Research Reviews 27 3 317 352 10.1002/med.20092 16991100 1:CAS:528:DC%2BD2sXmtVGrt7g%3D (Pubitemid 46668937)
    • (2007) Medicinal Research Reviews , vol.27 , Issue.3 , pp. 317-352
    • Mocellin, S.1    Bronte, V.2    Nitti, D.3
  • 132
    • 77957564570 scopus 로고    scopus 로고
    • Extracellular adenosine triphosphate and adenosine in cancer
    • doi: 10.1038/onc.2010.292
    • Stagg, J., & Smyth, M. J. Extracellular adenosine triphosphate and adenosine in cancer. Oncogene, doi: 10.1038/onc.2010.292.
    • Oncogene
    • Stagg, J.1    Smyth, M.J.2
  • 133
    • 77951234655 scopus 로고    scopus 로고
    • Generation and accumulation of immunosuppressive adenosine by human cd4+cd25highfoxp3+ regulatory t cells
    • doi: 10.1074/jbc.M109.047423
    • Mandapathil, M., Hilldorfer, B., Szczepanski, M. J., Czystowska, M., Szajnik, M., Ren, J., et al. Generation and accumulation of immunosuppressive adenosine by human cd4+cd25highfoxp3+ regulatory t cells. Journal of Biological Chemistry, 285(10), 7176-7186, doi: 10.1074/jbc.M109.047423.
    • Journal of Biological Chemistry , vol.285 , Issue.10 , pp. 7176-7186
    • Mandapathil, M.1    Hilldorfer, B.2    Szczepanski, M.J.3    Czystowska, M.4    Szajnik, M.5    Ren, J.6
  • 134
    • 77950231071 scopus 로고    scopus 로고
    • Cd73 on tumor cells impairs antitumor t-cell responses: A novel mechanism of tumor-induced immune suppression
    • doi: 10.1158/0008-5472.CAN-09-3109
    • Jin, D., Fan, J., Wang, L., Thompson, L. F., Liu, A., Daniel, B. J., et al. Cd73 on tumor cells impairs antitumor t-cell responses: A novel mechanism of tumor-induced immune suppression. Cancer Research, 70(6), 2245-2255, doi: 10.1158/0008-5472.CAN-09-3109.
    • Cancer Research , vol.70 , Issue.6 , pp. 2245-2255
    • Jin, D.1    Fan, J.2    Wang, L.3    Thompson, L.F.4    Liu, A.5    Daniel, B.J.6
  • 135
    • 44449146084 scopus 로고    scopus 로고
    • CD73-generated adenosine restricts lymphocyte migration into draining lymph nodes
    • 1:CAS:528:DC%2BD1cXkvVCjt70%3D
    • M Takedachi D Qu Y Ebisuno H Oohara ML Joachims ST McGee, et al. 2008 CD73-generated adenosine restricts lymphocyte migration into draining lymph nodes Journal of Immunology 180 9 6288 6296 1:CAS:528:DC%2BD1cXkvVCjt70%3D
    • (2008) Journal of Immunology , vol.180 , Issue.9 , pp. 6288-6296
    • Takedachi, M.1    Qu, D.2    Ebisuno, Y.3    Oohara, H.4    Joachims, M.L.5    McGee, S.T.6
  • 137
    • 0142137237 scopus 로고    scopus 로고
    • Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase
    • DOI 10.1038/nm934
    • C Uyttenhove L Pilotte I Theate V Stroobant D Colau N Parmentier, et al. 2003 Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2, 3-dioxygenase Natural Medicines 9 10 1269 1274 10.1038/nm934 nm934 1:CAS:528:DC%2BD3sXns1Clu7c%3D (Pubitemid 37279849)
    • (2003) Nature Medicine , vol.9 , Issue.10 , pp. 1269-1274
    • Uyttenhove, C.1    Pilotte, L.2    Theate, I.3    Stroobant, V.4    Colau, D.5    Parmentier, N.6    Boon, T.7    Van Den Eynde, B.J.8
  • 138
    • 74849101015 scopus 로고    scopus 로고
    • Indoleamine 2, 3-dioxygenase, an emerging target for anti-cancer therapy
    • 20025603 1:CAS:528:DC%2BC3cXhslKnsLk%3D
    • X Liu RC Newton SM Friedman PA Scherle 2009 Indoleamine 2, 3-dioxygenase, an emerging target for anti-cancer therapy Current Cancer Drug Targets 9 8 938 952 20025603 1:CAS:528:DC%2BC3cXhslKnsLk%3D
    • (2009) Current Cancer Drug Targets , vol.9 , Issue.8 , pp. 938-952
    • Liu, X.1    Newton, R.C.2    Friedman, S.M.3    Scherle, P.A.4
  • 139
    • 67649432744 scopus 로고    scopus 로고
    • Inhibitors of indoleamine-2, 3-dioxygenase for cancer therapy: Can we see the wood for the trees?
    • 10.1038/nrc2639 19461669
    • S Lob A Konigsrainer HG Rammensee G Opelz P Terness 2009 Inhibitors of indoleamine-2, 3-dioxygenase for cancer therapy: can we see the wood for the trees? Nature Reviews. Cancer 9 6 445 452 10.1038/nrc2639 19461669
    • (2009) Nature Reviews. Cancer , vol.9 , Issue.6 , pp. 445-452
    • Lob, S.1    Konigsrainer, A.2    Rammensee, H.G.3    Opelz, G.4    Terness, P.5
  • 143
    • 34248173331 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase and tumor-induced tolerance
    • DOI 10.1172/JCI31178
    • DH Munn AL Mellor 2007 Indoleamine 2, 3-dioxygenase and tumor-induced tolerance Journal of Clinical Investigation 117 5 1147 1154 10.1172/JCI31178 17476344 1:CAS:528:DC%2BD2sXlt1Omtro%3D (Pubitemid 46718399)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.5 , pp. 1147-1154
    • Munn, D.H.1    Mellor, A.L.2
  • 144
    • 33847388907 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase in immune suppression and cancer
    • DOI 10.2174/156800907780006896
    • AJ Muller GC Prendergast 2007 Indoleamine 2, 3-dioxygenase in immune suppression and cancer Current Cancer Drug Targets 7 1 31 40 17305476 1:CAS:528:DC%2BD2sXitVOgtr4%3D (Pubitemid 46345506)
    • (2007) Current Cancer Drug Targets , vol.7 , Issue.1 , pp. 31-40
    • Muller, A.J.1    Prendergast, G.C.2
  • 145
    • 16244408626 scopus 로고    scopus 로고
    • Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy
    • DOI 10.1038/nm1196
    • AJ Muller JB DuHadaway PS Donover E Sutanto-Ward GC Prendergast 2005 Inhibition of indoleamine 2, 3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy Natural Medicines 11 3 312 319 10.1038/nm1196 1:CAS:528:DC%2BD2MXhvVSru7c%3D (Pubitemid 40460560)
    • (2005) Nature Medicine , vol.11 , Issue.3 , pp. 312-319
    • Muller, A.J.1    DuHadaway, J.B.2    Donover, P.S.3    Sutanto-Ward, E.4    Prendergast, G.C.5
  • 146
    • 36148978529 scopus 로고    scopus 로고
    • Cyclooxygenases, prostanoids, and tumor progression
    • DOI 10.1007/s10555-007-9096-5, Forty Years of Metastasis Research: A Tribute to Dr. Isaiah J. Fidler
    • MT Wang KV Honn D Nie 2007 Cyclooxygenases, prostanoids, and tumor progression Cancer and Metastasis Reviews 26 3-4 525 534 10.1007/s10555-007- 9096-5 17763971 1:CAS:528:DC%2BD2sXht1yktLbP (Pubitemid 350115125)
    • (2007) Cancer and Metastasis Reviews , vol.26 , Issue.3-4 , pp. 525-534
    • Wang, M.-T.1    Honn, K.V.2    Nie, D.3
  • 147
    • 0141963117 scopus 로고    scopus 로고
    • Inhibitors of cyclo-oxygenase 2: A new class of anticancer agents?
    • DOI 10.1016/S1470-2045(03)01220-8
    • G Gasparini R Longo R Sarmiento A Morabito 2003 Inhibitors of cyclo-oxygenase 2: a new class of anticancer agents? The Lancet Oncology 4 10 605 615 14554238 1:CAS:528:DC%2BD3sXnvVKksbo%3D (Pubitemid 37258402)
    • (2003) Lancet Oncology , vol.4 , Issue.10 , pp. 605-615
    • Gasparini, G.1    Longo, R.2    Sarmiento, R.3    Morabito, A.4
  • 148
    • 34447120115 scopus 로고    scopus 로고
    • Back to the future: COX-2 inhibitors for chemoprevention and cancer therapy
    • DOI 10.2174/138955707780859431
    • FH Sarkar S Adsule Y Li S Padhye 2007 Back to the future: COX-2 inhibitors for chemoprevention and cancer therapy Mini Rev Med Chem 7 6 599 608 17584158 1:CAS:528:DC%2BD2sXlvFGmtr8%3D (Pubitemid 47099180)
    • (2007) Mini-Reviews in Medicinal Chemistry , vol.7 , Issue.6 , pp. 599-608
    • Sarkar, F.H.1    Adsule, S.2    Li, Y.3    Padhye, S.4
  • 149
    • 62349138124 scopus 로고    scopus 로고
    • The COX-2/PGE2 pathway: Key roles in the hallmarks of cancer and adaptation to the tumour microenvironment
    • 10.1093/carcin/bgp014 19136477 1:CAS:528:DC%2BD1MXivFSiuro%3D
    • A Greenhough HJ Smartt AE Moore HR Roberts AC Williams C Paraskeva, et al. 2009 The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment Carcinogenesis 30 3 377 386 10.1093/carcin/bgp014 19136477 1:CAS:528:DC%2BD1MXivFSiuro%3D
    • (2009) Carcinogenesis , vol.30 , Issue.3 , pp. 377-386
    • Greenhough, A.1    Smartt, H.J.2    Moore, A.E.3    Roberts, H.R.4    Williams, A.C.5    Paraskeva, C.6
  • 150
    • 0036499224 scopus 로고    scopus 로고
    • Prostaglandins as modulators of immunity
    • DOI 10.1016/S1471-4906(01)02154-8, PII S1471490601021548
    • SG Harris J Padilla L Koumas D Ray RP Phipps 2002 Prostaglandins as modulators of immunity Trends in Immunology 23 3 144 150 11864843 1:CAS:528:DC%2BD38XhsFaht7w%3D (Pubitemid 34178297)
    • (2002) Trends in Immunology , vol.23 , Issue.3 , pp. 144-150
    • Harris, S.G.1    Padilla, J.2    Koumas, L.3    Ray, D.4    Phipps, R.P.5
  • 152
    • 20444464066 scopus 로고    scopus 로고
    • + T regulatory cell activities in lung cancer
    • DOI 10.1158/0008-5472.CAN-05-0141
    • S Sharma SC Yang L Zhu K Reckamp B Gardner F Baratelli, et al. 2005 Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer Cancer Research 65 12 5211 5220 10.1158/0008-5472.CAN-05-0141 15958566 1:CAS:528:DC%2BD2MXltFemurc%3D (Pubitemid 40827331)
    • (2005) Cancer Research , vol.65 , Issue.12 , pp. 5211-5220
    • Sharma, S.1    Yang, S.-C.2    Zhu, L.3    Reckamp, K.4    Gardner, B.5    Baratelli, F.6    Huang, M.7    Batra, R.K.8    Dubinett, S.M.9
  • 154
  • 155
    • 2442686929 scopus 로고    scopus 로고
    • Combination of a poxvirus-based vaccine with a cyclooxygenase-2 inhibitor (celecoxib) elicits antitumor immunity and long-term survival in CEA.Tg/MIN mice
    • DOI 10.1158/0008-5472.CAN-03-3878
    • Zeytin, H. E., Patel, A. C., Rogers, C. J., Canter, D., Hursting, S. D., Schlom, J., et al. (2004). Combination of a poxvirus-based vaccine with a cyclooxygenase-2 inhibitor (celecoxib) elicits antitumor immunity and long-term survival in cea.Tg/min mice. Cancer Research, 64(10), 3668-3678, doi: 10.1158/0008-5472.CAN-03-3878. (Pubitemid 38657947)
    • (2004) Cancer Research , vol.64 , Issue.10 , pp. 3668-3678
    • Zeytin, H.E.1    Patel, A.C.2    Rogers, C.J.3    Canter, D.4    Hursting, S.D.5    Schlom, J.6    Greiner, J.W.7
  • 156
    • 25144442153 scopus 로고    scopus 로고
    • Targeting cyclooxygenase-2 in recurrent non-small cell lung cancer: A phase II trial of celecoxib and docetaxel
    • DOI 10.1158/1078-0432.CCR-05-0436
    • I Csiki JD Morrow A Sandler Y Shyr J Oates MK Williams, et al. 2005 Targeting cyclooxygenase-2 in recurrent non-small cell lung cancer: a phase ii trial of celecoxib and docetaxel Clinical Cancer Research 11 18 6634 6640 10.1158/1078-0432.CCR-05-0436 16166442 1:CAS:528:DC%2BD2MXhtVShsbzO (Pubitemid 41339004)
    • (2005) Clinical Cancer Research , vol.11 , Issue.18 , pp. 6634-6640
    • Csiki, I.1    Morrow, J.D.2    Sandler, A.3    Shyr, Y.4    Oates, J.5    Williams, M.K.6    Dang, T.7    Carbone, D.P.8    Johnson, D.H.9


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