메뉴 건너뛰기




Volumn 107, Issue 4, 2010, Pages 1547-1552

Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis

Author keywords

Adenosine; Cancer; Chemotaxis; Immunosuppression; Regulatory

Indexed keywords

5' NUCLEOTIDASE; MONOCLONAL ANTIBODY;

EID: 75949112218     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0908801107     Document Type: Article
Times cited : (492)

References (47)
  • 1
  • 2
    • 0036102125 scopus 로고    scopus 로고
    • CD39 is the dominant Langerhans cell-associated ecto-NTPDase: Modulatory roles in inflammation and immune responsiveness
    • Mizumoto N, et al. (2002) CD39 is the dominant Langerhans cell-associated ecto-NTPDase: Modulatory roles in inflammation and immune responsiveness. Nat Med 8: 358-365.
    • (2002) Nat Med , vol.8 , pp. 358-365
    • Mizumoto, N.1
  • 3
    • 65249138361 scopus 로고    scopus 로고
    • Contribution of adenosine A2B receptors to inflammatory parameters of experimental colitis
    • Frick JS, et al. (2009) Contribution of adenosine A2B receptors to inflammatory parameters of experimental colitis. J Immunol 182:4957-4964.
    • (2009) J Immunol , vol.182 , pp. 4957-4964
    • Frick, J.S.1
  • 4
    • 52649138296 scopus 로고    scopus 로고
    • Adenosine receptors in regulation of dendritic cell differentiation and function
    • Novitskiy SV, et al. (2008) Adenosine receptors in regulation of dendritic cell differentiation and function. Blood 112:1822-1831.
    • (2008) Blood , vol.112 , pp. 1822-1831
    • Novitskiy, S.V.1
  • 5
    • 58149147369 scopus 로고    scopus 로고
    • Hypoxia-adenosinergic immunosuppression: Tumor protection by T regulatory cells and cancerous tissue hypoxia
    • Sitkovsky MV, Kjaergaard J, Lukashev D, Ohta A (2008) Hypoxia-adenosinergic immunosuppression: Tumor protection by T regulatory cells and cancerous tissue hypoxia. Clin Cancer Res 14:5947-5952.
    • (2008) Clin Cancer Res , vol.14 , pp. 5947-5952
    • Sitkovsky, M.V.1    Kjaergaard, J.2    Lukashev, D.3    Ohta, A.4
  • 6
    • 51049101334 scopus 로고    scopus 로고
    • Adenosine receptors: Therapeutic aspects for inflammatory and immune diseases
    • Haskó G, Linden J, Cronstein B, Pacher P (2008) Adenosine receptors: Therapeutic aspects for inflammatory and immune diseases. Nat Rev Drug Discov 7:759-770.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 759-770
    • Haskó, G.1    Linden, J.2    Cronstein, B.3    Pacher, P.4
  • 7
    • 0035040532 scopus 로고    scopus 로고
    • Molecular approach to adenosine receptors: Receptor-mediated mechanisms of tissue protection
    • Linden J (2001) Molecular approach to adenosine receptors: Receptor-mediated mechanisms of tissue protection. Annu Rev Pharmacol Toxicol 41:775-787.
    • (2001) Annu Rev Pharmacol Toxicol , vol.41 , pp. 775-787
    • Linden, J.1
  • 8
    • 33748357735 scopus 로고    scopus 로고
    • A2A adenosine receptor protects tumors from antitumor T cells
    • Ohta A, et al. (2006) A2A adenosine receptor protects tumors from antitumor T cells. Proc Natl Acad Sci USA 103:13132-13137.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 13132-13137
    • Ohta, A.1
  • 9
    • 50249085890 scopus 로고    scopus 로고
    • Increased level of extracellular ATP at tumor sites: In vivo imaging with plasma membrane luciferase
    • Pellegatti P, et al. (2008) Increased level of extracellular ATP at tumor sites: In vivo imaging with plasma membrane luciferase. PLoS One 3:e2599.
    • (2008) PLoS One , vol.3
    • Pellegatti, P.1
  • 10
    • 40249106427 scopus 로고    scopus 로고
    • Inhibition of T cell and natural killer cell function by adenosine and its contribution to immune evasion by tumor cells (Review)
    • Hoskin DW, Mader JS, Furlong SJ, Conrad DM, Blay J (2008) Inhibition of T cell and natural killer cell function by adenosine and its contribution to immune evasion by tumor cells (Review). Int J Oncol 32:527-535.
    • (2008) Int J Oncol , vol.32 , pp. 527-535
    • Hoskin, D.W.1    Mader, J.S.2    Furlong, S.J.3    Conrad, D.M.4    Blay, J.5
  • 12
    • 0031933227 scopus 로고    scopus 로고
    • Ecto-enzyme and signaling functions of lymphocyte CD73
    • Resta R, Yamashita Y, Thompson LF (1998) Ecto-enzyme and signaling functions of lymphocyte CD73. Immunol Rev 161:95-109.
    • (1998) Immunol Rev , vol.161 , pp. 95-109
    • Resta, R.1    Yamashita, Y.2    Thompson, L.F.3
  • 13
    • 85047685683 scopus 로고    scopus 로고
    • Ecto-5′-nucleotidase (CD73) regulation by hypoxiainducible factor-1 mediates permeability changes in intestinal epithelia
    • Synnestvedt K, et al. (2002) Ecto-5′-nucleotidase (CD73) regulation by hypoxiainducible factor-1 mediates permeability changes in intestinal epithelia. J Clin Invest 110:993-1002.
    • (2002) J Clin Invest , vol.110 , pp. 993-1002
    • Synnestvedt, K.1
  • 14
    • 10644240767 scopus 로고    scopus 로고
    • Crucial role for ecto-5′-nucleotidase (CD73) in vascular leakage during hypoxia
    • Thompson LF, et al. (2004) Crucial role for ecto-5′-nucleotidase (CD73) in vascular leakage during hypoxia. J Exp Med 200:1395-1405.
    • (2004) J Exp Med , vol.200 , pp. 1395-1405
    • Thompson, L.F.1
  • 15
    • 58149250587 scopus 로고    scopus 로고
    • IFN-beta regulates CD73 and adenosine expression at the blood-brain barrier
    • Niemelä J, et al. (2008) IFN-beta regulates CD73 and adenosine expression at the blood-brain barrier. Eur J Immunol 38:2718-2726.
    • (2008) Eur J Immunol , vol.38 , pp. 2718-2726
    • Niemelä, J.1
  • 16
    • 0032547817 scopus 로고    scopus 로고
    • Neutrophil-derived 5′-adenosine monophosphate promotes endothelial barrier function via CD73-mediated conversion to adenosine and endothelial A2B receptor activation
    • Lennon PF, Taylor CT, Stahl GL, Colgan SP (1998) Neutrophil-derived 5′-adenosine monophosphate promotes endothelial barrier function via CD73-mediated conversion to adenosine and endothelial A2B receptor activation. J Exp Med 188: 1433-1443.
    • (1998) J Exp Med , vol.188 , pp. 1433-1443
    • Lennon, P.F.1    Taylor, C.T.2    Stahl, G.L.3    Colgan, S.P.4
  • 17
    • 44449146084 scopus 로고    scopus 로고
    • CD73-generated adenosine restricts lymphocyte migration into draining lymph nodes
    • Takedachi M, et al. (2008) CD73-generated adenosine restricts lymphocyte migration into draining lymph nodes. J Immunol 180:6288-6296.
    • (2008) J Immunol , vol.180 , pp. 6288-6296
    • Takedachi, M.1
  • 18
    • 0027258364 scopus 로고
    • 5′-adenosine monophosphate is the neutrophil-derived paracrine factor that elicits chloride secretion from T84 intestinal epithelial cell monolayers
    • Madara JL, et al. (1993) 5′-adenosine monophosphate is the neutrophil-derived paracrine factor that elicits chloride secretion from T84 intestinal epithelial cell monolayers. J Clin Invest 91:2320-2325.
    • (1993) J Clin Invest , vol.91 , pp. 2320-2325
    • Madara, J.L.1
  • 19
    • 77951623666 scopus 로고    scopus 로고
    • Differential ectonucleotidase expression in human bladder cancer cell lines
    • 10.1016/j.urolonc.2009.01.035
    • Stella J, et al. (2009) Differential ectonucleotidase expression in human bladder cancer cell lines. Urol Oncol, 10.1016/j.urolonc.2009.01.035.
    • (2009) Urol Oncol
    • Stella, J.1
  • 20
    • 47949117265 scopus 로고    scopus 로고
    • CD73 participates in cellular multiresistance program and protects against TRAIL-induced apoptosis
    • Mikhailov A, et al. (2008) CD73 participates in cellular multiresistance program and protects against TRAIL-induced apoptosis. J Immunol 181:464-475.
    • (2008) J Immunol , vol.181 , pp. 464-475
    • Mikhailov, A.1
  • 21
    • 55649124110 scopus 로고    scopus 로고
    • The role of ecto-5′-nucleotidase/CD73 in glioma cell line proliferation
    • Bavaresco L, et al. (2008) The role of ecto-5′-nucleotidase/CD73 in glioma cell line proliferation. Mol Cell Biochem 319:61-68.
    • (2008) Mol Cell Biochem , vol.319 , pp. 61-68
    • Bavaresco, L.1
  • 22
    • 0032782011 scopus 로고    scopus 로고
    • Expression of CD 73 (ecto-5?-nucleotidase) in 165 glioblastomas by immunohistochemistry and electronmicroscopic histochemistry
    • Ludwig HC, Rausch S, Schallock K, Markakis E (1999) Expression of CD 73 (ecto-5?-nucleotidase) in 165 glioblastomas by immunohistochemistry and electronmicroscopic histochemistry. Anticancer Res 19:1747-1752.
    • (1999) Anticancer Res , vol.19 , pp. 1747-1752
    • Ludwig, H.C.1    Rausch, S.2    Schallock, K.3    Markakis, E.4
  • 23
    • 33750472374 scopus 로고    scopus 로고
    • Ecto-5′-nucleotidase (eN, CD73) is coexpressed with metastasis promoting antigens in human melanoma cells
    • Sadej R, Spychala J, Skladanowski AC (2006) Ecto-5′-nucleotidase (eN, CD73) is coexpressed with metastasis promoting antigens in human melanoma cells. Nucleosides Nucleotides Nucleic Acids 25:1119-1123.
    • (2006) Nucleosides Nucleotides Nucleic Acids , vol.25 , pp. 1119-1123
    • Sadej, R.1    Spychala, J.2    Skladanowski, A.C.3
  • 24
    • 33745543989 scopus 로고    scopus 로고
    • In vitro evaluation of adenosine 5′-monophosphate as an imaging agent of tumor metabolism
    • Cho SY, et al. (2006) In vitro evaluation of adenosine 5′-monophosphate as an imaging agent of tumor metabolism. J Nucl Med 47:837-845.
    • (2006) J Nucl Med , vol.47 , pp. 837-845
    • Cho, S.Y.1
  • 25
    • 33645396217 scopus 로고    scopus 로고
    • Expression of CD73 and its ecto-5′-nucleotidase activity are elevated in papillary thyroid carcinomas
    • Kondo T, Nakazawa T, Murata SI, Katoh R (2006) Expression of CD73 and its ecto-5′-nucleotidase activity are elevated in papillary thyroid carcinomas. Histopathology 48: 612-614.
    • (2006) Histopathology , vol.48 , pp. 612-614
    • Kondo, T.1    Nakazawa, T.2    Murata, S.I.3    Katoh, R.4
  • 26
    • 7944225835 scopus 로고    scopus 로고
    • Differential gene expression profiles of radioresistant oesophageal cancer cell lines established by continuous fractionated irradiation
    • Fukuda K, et al. (2004) Differential gene expression profiles of radioresistant oesophageal cancer cell lines established by continuous fractionated irradiation. Br J Cancer 91:1543-1550.
    • (2004) Br J Cancer , vol.91 , pp. 1543-1550
    • Fukuda, K.1
  • 27
    • 26944496510 scopus 로고    scopus 로고
    • Combined affinity labelling and mass spectrometry analysis of differential cell surface protein expression in normal and prostate cancer cells
    • Hastie C, et al. (2005) Combined affinity labelling and mass spectrometry analysis of differential cell surface protein expression in normal and prostate cancer cells. Oncogene 24:5905-5913.
    • (2005) Oncogene , vol.24 , pp. 5905-5913
    • Hastie, C.1
  • 28
    • 0842311602 scopus 로고    scopus 로고
    • Role of estrogen receptor in the regulation of ecto-5?-nucleotidase and adenosine in breast cancer
    • Spychala J, et al. (2004) Role of estrogen receptor in the regulation of ecto-5?-nucleotidase and adenosine in breast cancer. Clin Cancer Res 10:708-717.
    • (2004) Clin Cancer Res , vol.10 , pp. 708-717
    • Spychala, J.1
  • 29
    • 38649133357 scopus 로고    scopus 로고
    • Ecto-5′-nucleotidase promotes invasion, migration and adhesion of human breast cancer cells
    • Wang L, et al. (2008) Ecto-5′-nucleotidase promotes invasion, migration and adhesion of human breast cancer cells. J Cancer Res Clin Oncol 134:365-372.
    • (2008) J Cancer Res Clin Oncol , vol.134 , pp. 365-372
    • Wang, L.1
  • 30
    • 0142117238 scopus 로고    scopus 로고
    • Gene expression profiling of tumor xenografts: In vivo analysis of organ-specific metastasis
    • Lee H, Lin EC, Liu L, Smith JW (2003) Gene expression profiling of tumor xenografts: In vivo analysis of organ-specific metastasis. Int J Cancer 107:528-534.
    • (2003) Int J Cancer , vol.107 , pp. 528-534
    • Lee, H.1    Lin, E.C.2    Liu, L.3    Smith, J.W.4
  • 31
    • 67049095042 scopus 로고    scopus 로고
    • Metastasis-related plasma membrane proteins of human breast cancer cells identified by comparative quantitative mass spectrometry
    • Leth-Larsen R, et al. (2009) Metastasis-related plasma membrane proteins of human breast cancer cells identified by comparative quantitative mass spectrometry. Mol Cell Proteomics 8:1436-1449.
    • (2009) Mol Cell Proteomics , vol.8 , pp. 1436-1449
    • Leth-Larsen, R.1
  • 32
    • 19944432209 scopus 로고    scopus 로고
    • Genomic analysis of a spontaneous model of breast cancer metastasis to bone reveals a role for the extracellular matrix
    • Eckhardt BL, et al. (2005) Genomic analysis of a spontaneous model of breast cancer metastasis to bone reveals a role for the extracellular matrix. Mol Cancer Res 3:1-13.
    • (2005) Mol Cancer Res , vol.3 , pp. 1-13
    • Eckhardt, B.L.1
  • 33
    • 33645728839 scopus 로고    scopus 로고
    • Human sebaceous tumors harbor inactivating mutations in LEF1
    • Takeda H, et al. (2006) Human sebaceous tumors harbor inactivating mutations in LEF1. Nat Med 12:395-397.
    • (2006) Nat Med , vol.12 , pp. 395-397
    • Takeda, H.1
  • 34
    • 0029835821 scopus 로고    scopus 로고
    • Evidence for the involvement of ecto-5′-nucleotidase (CD73) in drug resistance
    • Ujházy P, et al. (1996) Evidence for the involvement of ecto-5′-nucleotidase (CD73) in drug resistance. Int J Cancer 68:493-500.
    • (1996) Int J Cancer , vol.68 , pp. 493-500
    • Ujházy, P.1
  • 35
    • 34548435229 scopus 로고    scopus 로고
    • RNA interference of ecto-5′-nucleotidase (CD73) inhibits human breast cancer cell growth and invasion
    • Zhi X, et al. (2007) RNA interference of ecto-5′-nucleotidase (CD73) inhibits human breast cancer cell growth and invasion. Clin Exp Metastasis 24:439-448.
    • (2007) Clin Exp Metastasis , vol.24 , pp. 439-448
    • Zhi, X.1
  • 36
    • 33845708770 scopus 로고    scopus 로고
    • ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors
    • Chen Y, et al. (2006) ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors. Science 314:1792-1795.
    • (2006) Science , vol.314 , pp. 1792-1795
    • Chen, Y.1
  • 37
    • 33748861607 scopus 로고    scopus 로고
    • Adenosine upregulates CXCR4 and enhances the proliferative and migratory responses of human carcinoma cells to CXCL12/SDF-1alpha
    • Richard CL, Tan EY, Blay J (2006) Adenosine upregulates CXCR4 and enhances the proliferative and migratory responses of human carcinoma cells to CXCL12/SDF-1alpha. Int J Cancer 119:2044-2053.
    • (2006) Int J Cancer , vol.119 , pp. 2044-2053
    • Richard, C.L.1    Tan, E.Y.2    Blay, J.3
  • 38
    • 3042552700 scopus 로고    scopus 로고
    • Adenosine down-regulates the surface expression of dipeptidyl peptidase IV on HT-29 human colorectal carcinoma cells: Implications for cancer cell behavior
    • Tan EY, Mujoomdar M, Blay J (2004) Adenosine down-regulates the surface expression of dipeptidyl peptidase IV on HT-29 human colorectal carcinoma cells: Implications for cancer cell behavior. Am J Pathol 165:319-330.
    • (2004) Am J Pathol , vol.165 , pp. 319-330
    • Tan, E.Y.1    Mujoomdar, M.2    Blay, J.3
  • 39
    • 0041976960 scopus 로고    scopus 로고
    • Spatial restriction of alpha4 integrin phosphorylation regulates lamellipodial stability and alpha4beta1-dependent cell migration
    • Goldfinger LE, Han J, Kiosses WB, Howe AK, Ginsberg MH (2003) Spatial restriction of alpha4 integrin phosphorylation regulates lamellipodial stability and alpha4beta1-dependent cell migration. J Cell Biol 162:731-741.
    • (2003) J Cell Biol , vol.162 , pp. 731-741
    • Goldfinger, L.E.1    Han, J.2    Kiosses, W.B.3    Howe, A.K.4    Ginsberg, M.H.5
  • 40
    • 58149314551 scopus 로고    scopus 로고
    • Integrin-mediated protein kinase A activation at the leading edge of migrating cells
    • Lim CJ, et al. (2008) Integrin-mediated protein kinase A activation at the leading edge of migrating cells. Mol Biol Cell 19:4930-4941.
    • (2008) Mol Biol Cell , vol.19 , pp. 4930-4941
    • Lim, C.J.1
  • 41
    • 0034669958 scopus 로고    scopus 로고
    • CD73 engagement promotes lymphocyte binding to endothelial cells via a lymphocyte function-associated antigen-1-dependent mechanism
    • Airas L, Niemelä J, Jalkanen S (2000) CD73 engagement promotes lymphocyte binding to endothelial cells via a lymphocyte function-associated antigen-1-dependent mechanism. J Immunol 165:5411-5417.
    • (2000) J Immunol , vol.165 , pp. 5411-5417
    • Airas, L.1    Niemelä, J.2    Jalkanen, S.3
  • 42
    • 48249097173 scopus 로고    scopus 로고
    • CD73 is required for efficient entry of lymphocytes into the central nervous system during experimental autoimmune encephalomyelitis
    • Mills JH, et al. (2008) CD73 is required for efficient entry of lymphocytes into the central nervous system during experimental autoimmune encephalomyelitis. Proc Natl Acad Sci USA 105:9325-9330.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 9325-9330
    • Mills, J.H.1
  • 43
    • 58249121780 scopus 로고    scopus 로고
    • Inhibition of Siah ubiquitin ligase function
    • Möller A, et al. (2009) Inhibition of Siah ubiquitin ligase function. Oncogene 28: 289-296.
    • (2009) Oncogene , vol.28 , pp. 289-296
    • Möller, A.1
  • 44
    • 55849105625 scopus 로고    scopus 로고
    • Antibodies targeted to TRAIL receptor-2 and ErbB-2 synergize in vivo and induce an antitumor immune response
    • Stagg J, et al. (2008) Antibodies targeted to TRAIL receptor-2 and ErbB-2 synergize in vivo and induce an antitumor immune response. Proc Natl Acad Sci USA 105: 16254-16259.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 16254-16259
    • Stagg, J.1
  • 45
    • 41349114840 scopus 로고    scopus 로고
    • A2B adenosine receptor dampens hypoxia-induced vascular leak
    • Eckle T, et al. (2008) A2B adenosine receptor dampens hypoxia-induced vascular leak. Blood 111:2024-2035.
    • (2008) Blood , vol.111 , pp. 2024-2035
    • Eckle, T.1
  • 46
    • 69449097667 scopus 로고    scopus 로고
    • Selective deletion of the A1 adenosine receptor abolishes heart-rate slowing effects of intravascular adenosine in vivo
    • Koeppen M, Eckle T, Eltzschig HK (2009) Selective deletion of the A1 adenosine receptor abolishes heart-rate slowing effects of intravascular adenosine in vivo. PLoS One 4:e6784.
    • (2009) PLoS One , vol.4
    • Koeppen, M.1    Eckle, T.2    Eltzschig, H.K.3
  • 47
    • 34250351459 scopus 로고    scopus 로고
    • Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
    • Deaglio S, et al. (2007) Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. J Exp Med 204:1257-1265.
    • (2007) J Exp Med , vol.204 , pp. 1257-1265
    • Deaglio, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.