메뉴 건너뛰기




Volumn 1, Issue 1, 2009, Pages 109-127

Chemokine - Chemokine receptors in cancer immunotherapy

Author keywords

Anticancer; Chemokine; Immunotherapy; Target; Tumor

Indexed keywords

CCL16 CHEMOKINE; CHEMOKINE; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR3; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR4 ANTAGONIST; CTCE 9908; CXCL9 CHEMOKINE; DNA VACCINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLYCOSAMINOGLYCAN; HEPARIN; HEPARIN DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUTRALIZING ANTIBODY; RANTES; SECONDARY LYMPHOID TISSUE CHEMOKINE; SIMVASTATIN; STROMAL CELL DERIVED FACTOR 1; TUMOR ANTIGEN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 77953437752     PISSN: 1750743X     EISSN: None     Source Type: Journal    
DOI: 10.2217/1750743X.1.1.109     Document Type: Review
Times cited : (24)

References (169)
  • 1
    • 33748873913 scopus 로고    scopus 로고
    • Chemokines and cancer
    • Zlotnik A: Chemokines and cancer. Int. J. Cancer 119, 2026-2029 (2006).
    • (2006) Int. J. Cancer , vol.119 , pp. 2026-2029
    • Zlotnik, A.1
  • 2
    • 0842324615 scopus 로고    scopus 로고
    • Chemokines: Multiple levels of leukocyte migration control
    • DOI 10.1016/j.it.2003.12.005
    • Moser B, Wolf M, Walz A, Loetscher P: Chemokines: multiple levels of leukocyte migration control. Trends Immunol. 25, 75-84 (2004). (Pubitemid 38167488)
    • (2004) Trends in Immunology , vol.25 , Issue.2 , pp. 75-84
    • Moser, B.1    Wolf, M.2    Walz, A.3    Loetscher, P.4
  • 3
    • 33644828305 scopus 로고    scopus 로고
    • Chemokines and chemokine receptors: Their manifold roles in homeostasis and disease
    • Le Y, Zhou Y, Iribarren P, Wang J: Chemokines and chemokine receptors: their manifold roles in homeostasis and disease. Cell. Mol. Immunol. 1, 95-104 (2004).
    • (2004) Cell. Mol. Immunol. , vol.1 , pp. 95-104
    • Le, Y.1    Zhou, Y.2    Iribarren, P.3    Wang, J.4
  • 4
    • 0034658661 scopus 로고    scopus 로고
    • Chemokine receptors and their role in inflammation and infectious diseases
    • Murdoch C, Finn A: Chemokine receptors and their role in inflammation and infectious diseases. Blood 95, 3032-3043 (2000). (Pubitemid 30321151)
    • (2000) Blood , vol.95 , Issue.10 , pp. 3032-3043
    • Murdoch, C.1    Finn, A.2
  • 5
    • 0033646464 scopus 로고    scopus 로고
    • The chemokine receptor switch paradigm and dendritic cell migration: Its significance in tumor tissues
    • Allavena P, Sica A, Vecchi A, Locati M, Sozzani S, Mantovani A: The chemokine receptor switch paradigm and dendritic cell migration: its significance in tumor tissues. Immunol. Rev. 177, 141-149 (2000).
    • (2000) Immunol. Rev. , vol.177 , pp. 141-149
    • Allavena, P.1    Sica, A.2    Vecchi, A.3    Locati, M.4    Sozzani, S.5    Mantovani, A.6
  • 6
    • 0031849974 scopus 로고    scopus 로고
    • Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sites
    • Dieu MC, Vanbervliet B, Vicari A et al.: Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sites. J. Exp. Med. 188, 373-386 (1998).
    • (1998) J. Exp. Med. , vol.188 , pp. 373-386
    • Dieu, M.C.1    Vanbervliet, B.2    Vicari, A.3
  • 7
    • 0032901694 scopus 로고    scopus 로고
    • Chemokines: Signal lamps for trafficking of T and B cells for development and effector function
    • Kim CH, Broxmeyer HE: Chemokines: signal lamps for trafficking of T and B cells for development and effector function. J. Leukoc. Biol. 65, 6-15 (1999).
    • (1999) J. Leukoc. Biol. , vol.65 , pp. 6-15
    • Kim, C.H.1    Broxmeyer, H.E.2
  • 8
    • 16844382244 scopus 로고    scopus 로고
    • Chemokine-mediated control of T cell traffic in lymphoid and peripheral tissues
    • Ebert LM, Schaerli P, Moser B: Chemokine-mediated control of T cell traffic in lymphoid and peripheral tissues. Mol. Immunol. 42, 799-809 (2005).
    • (2005) Mol. Immunol. , vol.42 , pp. 799-809
    • Ebert, L.M.1    Schaerli, P.2    Moser, B.3
  • 9
    • 0033637307 scopus 로고    scopus 로고
    • Dendritic cell biology and regulation of dendritic cell trafficking by chemokines
    • Caux C, Ait-Yahia S, Chemin K et al.: Dendritic cell biology and regulation of dendritic cell trafficking by chemokines. Springer Semin. Immunopathol. 22, 345-369 (2000).
    • (2000) Springer Semin. Immunopathol. , vol.22 , pp. 345-369
    • Caux, C.1    Ait-Yahia, S.2    Chemin, K.3
  • 10
    • 0036378142 scopus 로고    scopus 로고
    • Chemokines and dendritic cells: A crucial alliance
    • McColl SR: Chemokines and dendritic cells: a crucial alliance. Immunol. Cell Biol. 80, 489-496 (2002).
    • (2002) Immunol. Cell Biol. , vol.80 , pp. 489-496
    • McColl, S.R.1
  • 11
    • 3042822267 scopus 로고    scopus 로고
    • Cancer and the chemokine network
    • Balkwill F: Cancer and the chemokine network. Nat. Rev. Cancer 4, 540-550 (2004).
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 540-550
    • Balkwill, F.1
  • 12
    • 0142166426 scopus 로고    scopus 로고
    • Chemokines: Agents for the immunotherapy of cancer?
    • Homey B, Muller A, Zlotnik A: Chemokines: agents for the immunotherapy of cancer? Nat. Rev. Immunol. 2, 175-184 (2002).
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 175-184
    • Homey, B.1    Muller, A.2    Zlotnik, A.3
  • 13
    • 49649117314 scopus 로고    scopus 로고
    • The chemokine receptor CXCR6 and its ligand CXCL16 are expressed in carcinomas and inhibit proliferation
    • Meijer J, Ogink J, Kreike B, Nuyten D, de Visser KE, Roos E: The chemokine receptor CXCR6 and its ligand CXCL16 are expressed in carcinomas and inhibit proliferation. Cancer Res. 68, 4701-4708 (2008).
    • (2008) Cancer Res. , vol.68 , pp. 4701-4708
    • Meijer, J.1    Ogink, J.2    Kreike, B.3    Nuyten, D.4    De Visser, K.E.5    Roos, E.6
  • 15
    • 0032948123 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells: In vivo neovascularization induced by stromal-derived factor-1α
    • Salcedo R, Wasserman K, Young HA et al.: Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells: in vivo neovascularization induced by stromal-derived factor-1α. Am. J. Pathol. 154, 1125-1135 (1999).
    • (1999) Am. J. Pathol. , vol.154 , pp. 1125-1135
    • Salcedo, R.1    Wasserman, K.2    Young, H.A.3
  • 16
    • 0034672252 scopus 로고    scopus 로고
    • I-309 binds to and activates endothelial cell functions and acts as an angiogenic molecule in vivo
    • Bernardini G, Spinetti G, Ribatti D et al.: I-309 binds to and activates endothelial cell functions and acts as an angiogenic molecule in vivo. Blood 96, 4039-4045 (2000).
    • (2000) Blood , vol.96 , pp. 4039-4045
    • Bernardini, G.1    Spinetti, G.2    Ribatti, D.3
  • 18
    • 35949002836 scopus 로고    scopus 로고
    • MCP-1 Promoter polymorphism at 2518 is associated with metastasis of nasopharyngeal carcinoma after treatment
    • Tse KP, Tsang NM, Chen KD et al.: MCP-1 Promoter polymorphism at 2518 is associated with metastasis of nasopharyngeal carcinoma after treatment. Clin. Cancer Res. 13, 6320-6326 (2007).
    • (2007) Clin. Cancer Res. , vol.13 , pp. 6320-6326
    • Tse, K.P.1    Tsang, N.M.2    Chen, K.D.3
  • 19
    • 12944335164 scopus 로고    scopus 로고
    • Breast cancer progression and host polymorphisms in the chemokine system: Role of the macrophage chemoattractant protein-1 (MCP-1) -2518 G allele
    • Ghilardi G, Biondi ML, La Torre A, Battaglioli L, Scorza R: Breast cancer progression and host polymorphisms in the chemokine system: role of the macrophage chemoattractant protein-1 (MCP-1) -2518 G allele. Clin. Chem. 51, 452-455 (2005).
    • (2005) Clin. Chem. , vol.51 , pp. 452-455
    • Ghilardi, G.1    Biondi, M.L.2    La Torre, A.3    Battaglioli, L.4    Scorza, R.5
  • 21
    • 16744362709 scopus 로고    scopus 로고
    • CCR5 expression influences the progression of human breast cancer in a p53-dependent manner
    • Manes S, Mira E, Colomer R et al.: CCR5 expression influences the progression of human breast cancer in a p53-dependent manner. J. Exp. Med. 198, 1381-1389 (2003).
    • (2003) J. Exp. Med. , vol.198 , pp. 1381-1389
    • Manes, S.1    Mira, E.2    Colomer, R.3
  • 22
    • 0035658072 scopus 로고    scopus 로고
    • Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells
    • Zou W, Machelon V, Coulomb-L'Hermin A et al.: Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells. Nat. Med. 7, 1339-1346 (2001).
    • (2001) Nat. Med. , vol.7 , pp. 1339-1346
    • Zou, W.1    Machelon, V.2    Coulomb-L'Hermin, A.3
  • 23
    • 40149107297 scopus 로고    scopus 로고
    • Chemokine system polymorphisms, survival and hepatocellular carcinoma occurrence in patients with hepatitis C virus-related cirrhosis
    • Nahon P, Sutton A, Rufat P et al.: Chemokine system polymorphisms, survival and hepatocellular carcinoma occurrence in patients with hepatitis C virus-related cirrhosis. World J. Gastroenterol. 14, 713-719 (2008).
    • (2008) World J. Gastroenterol. , vol.14 , pp. 713-719
    • Nahon, P.1    Sutton, A.2    Rufat, P.3
  • 24
    • 4444310914 scopus 로고    scopus 로고
    • Variants of the IL8 and IL8RB genes and risk for gastric cardia adenocarcinoma and esophageal squamous cell carcinoma
    • Savage SA, Abnet CC, Mark SD et al.: Variants of the IL8 and IL8RB genes and risk for gastric cardia adenocarcinoma and esophageal squamous cell carcinoma. Cancer Epidemiol. Biomarkers Prev. 13, 2251-2257 (2004).
    • (2004) Cancer Epidemiol. Biomarkers Prev. , vol.13 , pp. 2251-2257
    • Savage, S.A.1    Abnet, C.C.2    Mark, S.D.3
  • 25
    • 34247252408 scopus 로고    scopus 로고
    • The interleukin-8 (-251A/T) polymorphism is associated with increased risk for oral squamous cell carcinoma
    • Vairaktaris E, Yapijakis C, Serefoglou Z et al.: The interleukin-8 (-251A/T) polymorphism is associated with increased risk for oral squamous cell carcinoma. Eur. J. Surg. Oncol. 33, 504-507 (2007).
    • (2007) Eur. J. Surg. Oncol. , vol.33 , pp. 504-507
    • Vairaktaris, E.1    Yapijakis, C.2    Serefoglou, Z.3
  • 26
    • 34548478385 scopus 로고    scopus 로고
    • Association of IL-8 (-251)T/A polymorphism with susceptibility to and aggressiveness of nasopharyngeal carcinoma
    • Ben Nasr H, Chahed K, Mestiri S, Bouaouina N, Snoussi K, Chouchane L: Association of IL-8 (-251)T/A polymorphism with susceptibility to and aggressiveness of nasopharyngeal carcinoma. Hum. Immunol. 68, 761-769 (2007).
    • (2007) Hum. Immunol. , vol.68 , pp. 761-769
    • Ben Nasr, H.1    Chahed, K.2    Mestiri, S.3    Bouaouina, N.4    Snoussi, K.5    Chouchane, L.6
  • 27
    • 33646379379 scopus 로고    scopus 로고
    • Genetic variation in IL-8 associated with increased risk and poor prognosis of breast carcinoma
    • Along with [28], two recent papers that report a correlation of CXCL8 polymorphisms and breast cancer
    • Snoussi K, Mahfoudh W, Bouaouina N, Ahmed SB, Helal AN, Chouchane L: Genetic variation in IL-8 associated with increased risk and poor prognosis of breast carcinoma. Hum. Immunol. 67, 13-21 (2006). ■ Along with [28], two recent papers that report a correlation of CXCL8 polymorphisms and breast cancer.
    • (2006) Hum. Immunol. , vol.67 , Issue.13-21
    • Snoussi, K.1    Mahfoudh, W.2    Bouaouina, N.3    Ahmed, S.B.4    Helal, A.N.5    Chouchane, L.6
  • 28
    • 38949135757 scopus 로고    scopus 로고
    • Association of interleukin-8 (IL-8 or CXCL8) -251T/A and CXCR2 +1208C/T gene polymorphisms with breast cancer
    • Along with [27], two recent papers that report a correlation of CXCL8 polymorphisms and breast cancer
    • Kamali-Sarvestani E, Aliparasti MR, Atefi S: Association of interleukin-8 (IL-8 or CXCL8) -251T/A and CXCR2 +1208C/T gene polymorphisms with breast cancer. Neoplasma 54, 484-489 (2007). ■ Along with [27], two recent papers that report a correlation of CXCL8 polymorphisms and breast cancer.
    • (2007) Neoplasma , vol.54 , pp. 484-489
    • Kamali-Sarvestani, E.1    Aliparasti, M.R.2    Atefi, S.3
  • 29
    • 38949136379 scopus 로고    scopus 로고
    • Plasma stromal cell-derived factor-1: Host derived marker predictive of distant metastasis in breast cancer
    • Hassan S, Baccarelli A, Salvucci O, Basik M: Plasma stromal cell-derived factor-1: host derived marker predictive of distant metastasis in breast cancer. Clin. Cancer Res. 14, 446-454 (2008).
    • (2008) Clin. Cancer Res. , vol.14 , pp. 446-454
    • Hassan, S.1    Baccarelli, A.2    Salvucci, O.3    Basik, M.4
  • 31
    • 33845590593 scopus 로고    scopus 로고
    • CXCL12 polymorphism and malignant cell dissemination/tissue infiltration in acute myeloid leukemia
    • Dommange F, Cartron G, Espanel C et al.: CXCL12 polymorphism and malignant cell dissemination/tissue infiltration in acute myeloid leukemia. FASEB J. 20, 1913-1915 (2006).
    • (2006) FASEB J. , vol.20 , pp. 1913-1915
    • Dommange, F.1    Cartron, G.2    Espanel, C.3
  • 32
    • 34047233149 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1 chemokine gene variant in blood donors and chronic myelogenous leukemia patients
    • de Oliveira CE, Cavassin GG, Perim Ade L et al.: Stromal cell-derived factor-1 chemokine gene variant in blood donors and chronic myelogenous leukemia patients. J. Clin. Lab. Anal. 21, 49-54 (2007).
    • (2007) J. Clin. Lab. Anal. , vol.21 , pp. 49-54
    • De Oliveira, C.E.1    Cavassin, G.G.2    Perim Ade, L.3
  • 34
    • 34548824078 scopus 로고    scopus 로고
    • CXCL12 G801A polymorphism is a risk factor for sporadic prostate cancer susceptibility
    • Hirata H, Hinoda Y, Kikuno N et al.: CXCL12 G801A polymorphism is a risk factor for sporadic prostate cancer susceptibility. Clin. Cancer Res. 13, 5056-5062 (2007).
    • (2007) Clin. Cancer Res. , vol.13 , pp. 5056-5062
    • Hirata, H.1    Hinoda, Y.2    Kikuno, N.3
  • 35
    • 3042512151 scopus 로고    scopus 로고
    • Molecular investigation of the stromal cell-derived factor-1 chemokine in lymphoid leukemia and lymphoma patients from Brazil
    • de Oliveira Cavassin GG, De Lucca FL, Delgado Andre N et al.: Molecular investigation of the stromal cell-derived factor-1 chemokine in lymphoid leukemia and lymphoma patients from Brazil. Blood Cells Mol. Dis. 33, 90-93 (2004).
    • (2004) Blood Cells Mol. Dis. , vol.33 , pp. 90-93
    • De Oliveira Cavassin, G.G.1    De Lucca, F.L.2    Delgado Andre, N.3
  • 36
    • 9244224723 scopus 로고    scopus 로고
    • Intrinsic tumour suppression
    • Lowe SW, Cepero E, Evan G: Intrinsic tumour suppression. Nature 432, 307-315 (2004).
    • (2004) Nature , vol.432 , pp. 307-315
    • Lowe, S.W.1    Cepero, E.2    Evan, G.3
  • 37
    • 48349111663 scopus 로고    scopus 로고
    • Cancer: Ins and outs of tumour control
    • Outlines and compares three recent papers on tumor senescence pathways and their role in tumor progression
    • Soengas MS: Cancer: Ins and outs of tumour control. Nature 454, 586-587 (2008). ■■ Outlines and compares three recent papers on tumor senescence pathways and their role in tumor progression.
    • (2008) Nature , vol.454 , pp. 586-587
    • Soengas, M.S.1
  • 38
    • 0035834121 scopus 로고    scopus 로고
    • Senescent fibroblasts promote epithelial cell growth and tumorigenesis: A link between cancer and aging
    • Krtolica A, Parrinello S, Lockett S, Desprez PY, Campisi J: Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging. Proc. Natl Acad. Sci. USA 98, 12072-12077 (2001).
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 12072-12077
    • Krtolica, A.1    Parrinello, S.2    Lockett, S.3    Desprez, P.Y.4    Campisi, J.5
  • 39
    • 33749549246 scopus 로고    scopus 로고
    • Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence
    • Coppe JP, Kauser K, Campisi J, Beausejour CM: Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence. J. Biol. Chem. 281, 29568-29574 (2006).
    • (2006) J. Biol. Chem. , vol.281 , pp. 29568-29574
    • Coppe, J.P.1    Kauser, K.2    Campisi, J.3    Beausejour, C.M.4
  • 44
    • 33646255924 scopus 로고    scopus 로고
    • High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras
    • Wislez M, Fujimoto N, Izzo JG et al.: High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras. Cancer Res. 66, 4198-4207 (2006).
    • (2006) Cancer Res. , vol.66 , pp. 4198-4207
    • Wislez, M.1    Fujimoto, N.2    Izzo, J.G.3
  • 45
    • 38849168162 scopus 로고    scopus 로고
    • Oncogenic BRAF Induces Senescence and Apoptosis through Pathways Mediated by the Secreted Protein IGFBP7
    • DOI 10.1016/j.cell.2007.12.032, PII S0092867408000536
    • Wajapeyee N, Serra RW, Zhu X, Mahalingam M, Green MR: Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7. Cell 132, 363-374 (2008). (Pubitemid 351191995)
    • (2008) Cell , vol.132 , Issue.3 , pp. 363-374
    • Wajapeyee, N.1    Serra, R.W.2    Zhu, X.3    Mahalingam, M.4    Green, M.R.5
  • 46
    • 0028364780 scopus 로고
    • Expression of interleukin 8 correlates with the metastatic potential of human melanoma cells in nude mice
    • Singh RK, Gutman M, Radinsky R, Bucana CD, Fidler IJ: Expression of interleukin 8 correlates with the metastatic potential of human melanoma cells in nude mice. Cancer Res. 54, 3242-3247 (1994). (Pubitemid 24208936)
    • (1994) Cancer Research , vol.54 , Issue.12 , pp. 3242-3247
    • Singh, R.K.1    Gutman, M.2    Radinsky, R.3    Bucana, C.D.4    Fidler, I.J.5
  • 47
    • 23844530896 scopus 로고    scopus 로고
    • CCR7 and CXCR4 as novel biomarkers predicting axillary lymph node metastasis in T1 breast cancer
    • Cabioglu N, Yazici MS, Arun B et al.: CCR7 and CXCR4 as novel biomarkers predicting axillary lymph node metastasis in T1 breast cancer. Clin. Cancer Res. 11, 5686-5693 (2005).
    • (2005) Clin. Cancer Res. , vol.11 , pp. 5686-5693
    • Cabioglu, N.1    Yazici, M.S.2    Arun, B.3
  • 48
    • 10744226186 scopus 로고    scopus 로고
    • Association of CC chemokine receptor 7 with lymph node metastasis of esophageal squamous cell carcinoma
    • Ding Y, Shimada Y, Maeda M et al.: Association of CC chemokine receptor 7 with lymph node metastasis of esophageal squamous cell carcinoma. Clin. Cancer Res. 9, 3406-3412 (2003).
    • (2003) Clin. Cancer Res. , vol.9 , pp. 3406-3412
    • Ding, Y.1    Shimada, Y.2    Maeda, M.3
  • 51
    • 0037431546 scopus 로고    scopus 로고
    • Overexpression of CCR7 mRNA in nonsmall cell lung cancer: Correlation with lymph node metastasis
    • Takanami I: Overexpression of CCR7 mRNA in nonsmall cell lung cancer: correlation with lymph node metastasis. Int. J. Cancer 105, 186-189 (2003).
    • (2003) Int. J. Cancer , vol.105 , pp. 186-189
    • Takanami, I.1
  • 54
    • 2342591450 scopus 로고    scopus 로고
    • The significance of cancer cell expression of the chemokine receptor CXCR4
    • Highlights the importance of the CXCR4-CXCL12 axis in metastasis
    • Balkwill F: The significance of cancer cell expression of the chemokine receptor CXCR4. Semin. Cancer Biol. 14, 171-179 (2004). ■■ Highlights the importance of the CXCR4-CXCL12 axis in metastasis.
    • (2004) Semin. Cancer Biol. , vol.14 , pp. 171-179
    • Balkwill, F.1
  • 55
    • 33745334601 scopus 로고    scopus 로고
    • The role of CXCR4 receptor expression in breast cancer: A large tissue microarray study
    • Salvucci O, Bouchard A, Baccarelli A et al.: The role of CXCR4 receptor expression in breast cancer: a large tissue microarray study. Breast Cancer Res. Treat. 97, 275-283 (2006).
    • (2006) Breast Cancer Res. Treat. , vol.97 , pp. 275-283
    • Salvucci, O.1    Bouchard, A.2    Baccarelli, A.3
  • 58
    • 0038498102 scopus 로고    scopus 로고
    • NF-κB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4
    • Helbig G, Christopherson KW 2nd, Bhat-Nakshatri P et al.: NF-κB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4. J. Biol. Chem. 278, 21631-21638 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 21631-21638
    • Helbig, G.1    Christopherson II, K.W.2    Bhat-Nakshatri, P.3
  • 59
    • 33644789290 scopus 로고    scopus 로고
    • Stromal cell derived factor-1: Its influence on invasiveness and migration of breast cancer cells in vitro, and its association with prognosis and survival in human breast cancer
    • Kang H, Watkins G, Parr C, Douglas-Jones A, Mansel RE, Jiang WG: Stromal cell derived factor-1: its influence on invasiveness and migration of breast cancer cells in vitro, and its association with prognosis and survival in human breast cancer. Breast Cancer Res. 7, R402-10 (2005).
    • (2005) Breast Cancer Res. , vol.7
    • Kang, H.1    Watkins, G.2    Parr, C.3    Douglas-Jones, A.4    Mansel, R.E.5    Jiang, W.G.6
  • 60
    • 33746485766 scopus 로고    scopus 로고
    • Epidermal growth factor receptor targeting in cancer
    • Mendelsohn J, Baselga J: Epidermal growth factor receptor targeting in cancer. Semin. Oncol. 33, 369-385 (2006).
    • (2006) Semin. Oncol. , vol.33 , pp. 369-385
    • Mendelsohn, J.1    Baselga, J.2
  • 62
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
    • DOI 10.1016/j.cell.2005.02.034, PII S0092867405002370
    • Orimo A, Gupta PB, Sgroi DC et al.: Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 121, 335-348 (2005). (Pubitemid 40692295)
    • (2005) Cell , vol.121 , Issue.3 , pp. 335-348
    • Orimo, A.1    Gupta, P.B.2    Sgroi, D.C.3    Arenzana-Seisdedos, F.4    Delaunay, T.5    Naeem, R.6    Carey, V.J.7    Richardson, A.L.8    Weinberg, R.A.9
  • 63
    • 22244470409 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1α and CXCR4 expression in hemangioblastoma and clear cell-renal cell carcinoma: Von Hippel-Lindau loss-of-function induces expression of a ligand and its receptor
    • DOI 10.1158/0008-5472.CAN-04-4406
    • Zagzag D, Krishnamachary B, Yee H et al.: Stromal cell-derived factor-1α and CXCR4 expression in hemangioblastoma and clear cell-renal cell carcinoma: von Hippel-Lindau loss-of-function induces expression of a ligand and its receptor. Cancer Res. 65, 6178-6188 (2005). (Pubitemid 40994403)
    • (2005) Cancer Research , vol.65 , Issue.14 , pp. 6178-6188
    • Zagzag, D.1    Krishnamachary, B.2    Yee, H.3    Okuyama, H.4    Chiriboga, L.5    Ali, M.A.6    Melamed, J.7    Semenza, G.L.8
  • 64
    • 33644826473 scopus 로고    scopus 로고
    • Roots and stems: Stem cells in cancer
    • Polyak K, Hahn WC: Roots and stems: stem cells in cancer. Nat. Med. 12, 296-300 (2006).
    • (2006) Nat. Med. , vol.12 , pp. 296-300
    • Polyak, K.1    Hahn, W.C.2
  • 65
    • 32244439441 scopus 로고    scopus 로고
    • CD24 affects CXCR4 function in pre-B lymphocytes and breast carcinoma cells
    • Schabath H, Runz S, Joumaa S, Altevogt P: CD24 affects CXCR4 function in pre-B lymphocytes and breast carcinoma cells. J. Cell. Sci. 119, 314-325 (2006).
    • (2006) J. Cell. Sci. , vol.119 , pp. 314-325
    • Schabath, H.1    Runz, S.2    Joumaa, S.3    Altevogt, P.4
  • 66
    • 34748820033 scopus 로고    scopus 로고
    • Chemokine receptors in cancer metastasis and cancer cell-derived chemokines in host immune response
    • DOI 10.1111/j.1349-7006.2007.00606.x
    • Koizumi K, Hojo S, Akashi T, Yasumoto K, Saiki I: Chemokine receptors in cancer metastasis and cancer cell-derived chemokines in host immune response. Cancer Sci. 98, 1652-1658 (2007). (Pubitemid 47487897)
    • (2007) Cancer Science , vol.98 , Issue.11 , pp. 1652-1658
    • Koizumi, K.1    Hojo, S.2    Akashi, T.3    Yasumoto, K.4    Saiki, I.5
  • 67
    • 23844513413 scopus 로고    scopus 로고
    • Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: Pivotal role of the SDF-1-CXCR4 axis
    • DOI 10.1634/stemcells.2004-0342
    • Kucia M, Reca R, Miekus K et al.: Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis. Stem Cells 23, 879-894 (2005). (Pubitemid 41170944)
    • (2005) Stem Cells , vol.23 , Issue.7 , pp. 879-894
    • Kucia, M.1    Reca, R.2    Miekus, K.3    Wanzeck, J.4    Wojakowski, W.5    Janowska-Wieczorek, A.6    Ratajczak, J.7    Ratajczak, M.Z.8
  • 68
    • 2342575714 scopus 로고    scopus 로고
    • Regulation of the trafficking of tumour-infiltrating dendritic cells by chemokines
    • Vicari AP, Treilleux I, Lebecque S: Regulation of the trafficking of tumour-infiltrating dendritic cells by chemokines. Semin. Cancer Biol. 14, 161-169 (2004).
    • (2004) Semin. Cancer Biol. , vol.14 , pp. 161-169
    • Vicari, A.P.1    Treilleux, I.2    Lebecque, S.3
  • 69
    • 16844379997 scopus 로고    scopus 로고
    • Immunosuppressive networks in the tumour environment and their therapeutic relevance
    • How tumor-induced immunosuppression should be considered in the design of therapeutic strategies
    • Zou W: Immunosuppressive networks in the tumour environment and their therapeutic relevance. Nat. Rev. Cancer 5, 263-274 (2005). ■ How tumor-induced immunosuppression should be considered in the design of therapeutic strategies.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 263-274
    • Zou, W.1
  • 70
    • 0242611008 scopus 로고    scopus 로고
    • Immune evasion by murine melanoma mediated through CC chemokine receptor-10
    • Murakami T, Cardones AR, Finkelstein SE et al.: Immune evasion by murine melanoma mediated through CC chemokine receptor-10. J. Exp. Med. 198, 1337-1347 (2003).
    • (2003) J. Exp. Med. , vol.198 , pp. 1337-1347
    • Murakami, T.1    Cardones, A.R.2    Finkelstein, S.E.3
  • 71
    • 33646395923 scopus 로고    scopus 로고
    • Potential role of CCL27 and CCR10 expression in melanoma progression and immune escape
    • Simonetti O, Goteri G, Lucarini G et al.: Potential role of CCL27 and CCR10 expression in melanoma progression and immune escape. Eur. J. Cancer 42, 1181-1187 (2006).
    • (2006) Eur. J. Cancer , vol.42 , pp. 1181-1187
    • Simonetti, O.1    Goteri, G.2    Lucarini, G.3
  • 73
    • 0042744923 scopus 로고    scopus 로고
    • Eotaxin-3 is a natural antagonist for CCR2 and exerts a repulsive effect on human monocytes
    • DOI 10.1182/blood-2002-09-2773
    • Ogilvie P, Paoletti S, Clark-Lewis I, Uguccioni M: Eotaxin-3 is a natural antagonist for CCR2 and exerts a repulsive effect on human monocytes. Blood 102, 789-794 (2003). (Pubitemid 36917764)
    • (2003) Blood , vol.102 , Issue.3 , pp. 789-794
    • Ogilvie, P.1    Paoletti, S.2    Clark-Lewis, I.3    Uguccioni, M.4
  • 74
    • 33646090415 scopus 로고    scopus 로고
    • Neutrophil chemorepulsion in defined interleukin-8 gradients in vitro and in vivo
    • Tharp WG, Yadav R, Irimia D et al.: Neutrophil chemorepulsion in defined interleukin-8 gradients in vitro and in vivo. J. Leukoc. Biol. 79, 539-554 (2006).
    • (2006) J. Leukoc. Biol. , vol.79 , pp. 539-554
    • Tharp, W.G.1    Yadav, R.2    Irimia, D.3
  • 76
    • 33750455077 scopus 로고    scopus 로고
    • Sensitization of B16 tumor cells with a CXCR4 antagonist increases the efficacy of immunotherapy for established lung metastases
    • Lee CH, Kakinuma T, Wang J et al.: Sensitization of B16 tumor cells with a CXCR4 antagonist increases the efficacy of immunotherapy for established lung metastases. Mol. Cancer Ther. 5, 2592-2599 (2006).
    • (2006) Mol. Cancer Ther. , vol.5 , pp. 2592-2599
    • Lee, C.H.1    Kakinuma, T.2    Wang, J.3
  • 77
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • Pollard JW: Tumour-educated macrophages promote tumour progression and metastasis. Nat. Rev. Cancer 4, 71-78 (2004).
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 71-78
    • Pollard, J.W.1
  • 78
    • 40049088602 scopus 로고    scopus 로고
    • The inflammatory microenvironment in tumor progression: The role of tumor-associated macrophages
    • Allavena P, Sica A, Solinas G, Porta C, Mantovani A: The inflammatory microenvironment in tumor progression: the role of tumor-associated macrophages. Crit. Rev. Oncol. Hematol. 66, 1-9 (2008).
    • (2008) Crit. Rev. Oncol. Hematol. , vol.66 , pp. 1-9
    • Allavena, P.1    Sica, A.2    Solinas, G.3    Porta, C.4    Mantovani, A.5
  • 79
    • 33845524204 scopus 로고    scopus 로고
    • Role of tumor-associated macrophages in tumor progression and invasion
    • DOI 10.1007/s10555-006-9001-7, Special Issue on Pro-inflammatory Cytokines in Cancer
    • Mantovani A, Schioppa T, Porta C, Allavena P, Sica A: Role of tumor-associated macrophages in tumor progression and invasion. Cancer Metastasis Rev. 25, 315-322 (2006). (Pubitemid 44922352)
    • (2006) Cancer and Metastasis Reviews , vol.25 , Issue.3 , pp. 315-322
    • Mantovani, A.1    Schioppa, T.2    Porta, C.3    Allavena, P.4    Sica, A.5
  • 80
    • 0036187615 scopus 로고    scopus 로고
    • The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies
    • DOI 10.1002/path.1027
    • Bingle L, Brown NJ, Lewis CE: The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies. J. Pathol. 196, 254-265 (2002). (Pubitemid 34189413)
    • (2002) Journal of Pathology , vol.196 , Issue.3 , pp. 254-265
    • Bingle, L.1    Brown, N.J.2    Lewis, C.E.3
  • 81
    • 0033903714 scopus 로고    scopus 로고
    • Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer
    • Ueno T, Toi M, Saji H et al.: Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer. Clin. Cancer Res. 6, 3282-3289 (2000).
    • (2000) Clin. Cancer Res. , vol.6 , pp. 3282-3289
    • Ueno, T.1    Toi, M.2    Saji, H.3
  • 82
    • 31544451057 scopus 로고    scopus 로고
    • Correlations between serum monocyte chemotactic protein-1 levels, clinical prognostic factors, and HER-2/neu vaccine-related immunity in breast cancer patients
    • Dehqanzada ZA, Storrer CE, Hueman MT et al.: Correlations between serum monocyte chemotactic protein-1 levels, clinical prognostic factors, and HER-2/neu vaccine-related immunity in breast cancer patients. Clin. Cancer Res. 12, 478-486 (2006).
    • (2006) Clin. Cancer Res. , vol.12 , pp. 478-486
    • Dehqanzada, Z.A.1    Storrer, C.E.2    Hueman, M.T.3
  • 84
  • 86
    • 33846972342 scopus 로고    scopus 로고
    • Immunological responses can have both pro- And antitumour effects: Implications for immunotherapy
    • How immune responses can influence tumor progression and mechanisms whereby tumors escape recognition and destruction. Includes a brief review on the pros and cons of some preclinical models
    • Stewart TJ, Greeneltch KM, Lutsiak ME, Abrams SI: Immunological responses can have both pro- and antitumour effects: implications for immunotherapy. Expert Rev. Mol. Med. 9, 1-20 (2007). ■■ How immune responses can influence tumor progression and mechanisms whereby tumors escape recognition and destruction. Includes a brief review on the pros and cons of some preclinical models.
    • (2007) Expert Rev. Mol. Med. , vol.9 , pp. 1-20
    • Stewart, T.J.1    Greeneltch, K.M.2    Lutsiak, M.E.3    Abrams, S.I.4
  • 88
    • 4644237613 scopus 로고    scopus 로고
    • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
    • Curiel TJ, Coukos G, Zou L et al.: Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat. Med. 10, 942-949 (2004).
    • (2004) Nat. Med. , vol.10 , pp. 942-949
    • Curiel, T.J.1    Coukos, G.2    Zou, L.3
  • 89
    • 33745261751 scopus 로고    scopus 로고
    • Specific recruitment of CC chemokine receptor 4-positive regulatory T cells in Hodgkin lymphoma fosters immune privilege
    • DOI 10.1158/0008-5472.CAN-06-0261
    • Ishida T, Ishii T, Inagaki A et al.: Specific recruitment of CC chemokine receptor 4-positive regulatory T cells in Hodgkin lymphoma fosters immune privilege. Cancer Res. 66, 5716-5722 (2006). (Pubitemid 43927124)
    • (2006) Cancer Research , vol.66 , Issue.11 , pp. 5716-5722
    • Ishida, T.1    Ishii, T.2    Inagaki, A.3    Yano, H.4    Komatsu, H.5    Iida, S.6    Inagaki, H.7    Ueda, R.8
  • 90
    • 33750807427 scopus 로고    scopus 로고
    • high T cells are enriched in the tumor and peripheral blood of prostate cancer patients
    • high T cells are enriched in the tumor and peripheral blood of prostate cancer patients. J. Immunol. 177, 7398-7405 (2006).
    • (2006) J. Immunol. , vol.177 , pp. 7398-7405
    • Miller, A.M.1    Lundberg, K.2    Ozenci, V.3
  • 91
    • 35748975652 scopus 로고    scopus 로고
    • Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy
    • Jordan JT, Sun W, Hussain SF, DeAngulo G, Prabhu SS, Heimberger AB: Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy. Cancer Immunol. Immunother. 57, 123-131 (2008).
    • (2008) Cancer Immunol. Immunother. , vol.57 , pp. 123-131
    • Jordan, J.T.1    Sun, W.2    Hussain, S.F.3    Deangulo, G.4    Prabhu, S.S.5    Heimberger, A.B.6
  • 93
    • 33748933230 scopus 로고    scopus 로고
    • CCR4 as a novel molecular target for immunotherapy of cancer
    • DOI 10.1111/j.1349-7006.2006.00307.x
    • Ishida T, Ueda R: CCR4 as a novel molecular target for immunotherapy of cancer. Cancer Sci. 97, 1139-1146 (2006). (Pubitemid 44430638)
    • (2006) Cancer Science , vol.97 , Issue.11 , pp. 1139-1146
    • Ishida, T.1    Ueda, R.2
  • 94
    • 46749136862 scopus 로고    scopus 로고
    • Expression of the Epstein-Barr virus-encoded Epstein-Barr virus nuclear antigen 1 in Hodgkin's lymphoma cells mediates up-regulation of CCL20 and the migration of regulatory T cells
    • Baumforth KR, Birgersdotter A, Reynolds GM et al.: Expression of the Epstein-Barr virus-encoded Epstein-Barr virus nuclear antigen 1 in Hodgkin's lymphoma cells mediates up-regulation of CCL20 and the migration of regulatory T cells. Am. J. Pathol. 173, 195-204 (2008).
    • (2008) Am. J. Pathol. , vol.173 , pp. 195-204
    • Baumforth, K.R.1    Birgersdotter, A.2    Reynolds, G.M.3
  • 96
    • 31344474166 scopus 로고    scopus 로고
    • Myeloid suppressor cells in cancer: Recruitment, phenotype, properties, and mechanisms of immune suppression
    • Serafini P, Borrello I, Bronte V: Myeloid suppressor cells in cancer: recruitment, phenotype, properties, and mechanisms of immune suppression. Semin. Cancer Biol. 16, 53-65 (2006).
    • (2006) Semin. Cancer Biol. , vol.16 , pp. 53-65
    • Serafini, P.1    Borrello, I.2    Bronte, V.3
  • 97
    • 0033179327 scopus 로고    scopus 로고
    • Nitric oxide mediation of active immunosuppression associated with graft-versus-host reaction
    • Bobe P, Benihoud K, Grandjon D, Opolon P, Pritchard LL, Huchet R: Nitric oxide mediation of active immunosuppression associated with graft-versus-host reaction. Blood 94, 1028-1037 (1999). (Pubitemid 29361835)
    • (1999) Blood , vol.94 , Issue.3 , pp. 1028-1037
    • Bobe, P.1    Benihoud, K.2    Grandjon, D.3    Opolon, P.4    Pritchard, L.L.5    Huchett, R.6
  • 100
    • 0027382922 scopus 로고
    • Suppressor macrophages in African trypanosomiasis inhibit T cell proliferative responses by nitric oxide and prostaglandins
    • Schleifer KW, Mansfield JM: Suppressor macrophages in African trypanosomiasis inhibit T cell proliferative responses by nitric oxide and prostaglandins. J. Immunol. 151, 5492-5503 (1993).
    • (1993) J. Immunol. , vol.151 , pp. 5492-5503
    • Schleifer, K.W.1    Mansfield, J.M.2
  • 101
    • 0742286811 scopus 로고    scopus 로고
    • Derangement of immune responses by myeloid suppressor cells
    • Serafini P, De Santo C, Marigo I et al.: Derangement of immune responses by myeloid suppressor cells. Cancer Immunol. Immunother. 53, 64-72 (2004).
    • (2004) Cancer Immunol. Immunother. , vol.53 , pp. 64-72
    • Serafini, P.1    De Santo, C.2    Marigo, I.3
  • 103
    • 34848887822 scopus 로고    scopus 로고
    • Pathways mediating the expansion and immunosuppressive activity of myeloid-derived suppressor cells and their relevance to cancer therapy
    • Outlines the roles that myeloid-derived suppressor cells can have on suppressing immune responses and highlights their relevance in anticancer therapy design
    • Talmadge JE: Pathways mediating the expansion and immunosuppressive activity of myeloid-derived suppressor cells and their relevance to cancer therapy. Clin. Cancer Res. 13, 5243-5248 (2007). ■ Outlines the roles that myeloid-derived suppressor cells can have on suppressing immune responses and highlights their relevance in anticancer therapy design.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 5243-5248
    • Talmadge, J.E.1
  • 104
    • 40149092963 scopus 로고    scopus 로고
    • Immune consequences of protracted host-tumor interactions in a transgenic mouse model of mammary carcinoma
    • Stewart TJ, Lutsiak ME, Abrams SI: Immune consequences of protracted host-tumor interactions in a transgenic mouse model of mammary carcinoma. Cancer Invest. 26, 237-249 (2008).
    • (2008) Cancer Invest. , vol.26 , pp. 237-249
    • Stewart, T.J.1    Lutsiak, M.E.2    Abrams, S.I.3
  • 106
    • 0035874990 scopus 로고    scopus 로고
    • Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of T-cell function in advanced cancer patients
    • Schmielau J, Finn OJ: Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of T-cell function in advanced cancer patients. Cancer Res. 61, 4756-4760 (2001). (Pubitemid 32691887)
    • (2001) Cancer Research , vol.61 , Issue.12 , pp. 4756-4760
    • Schmielau, J.1    Finn, O.J.2
  • 107
    • 20244367914 scopus 로고    scopus 로고
    • Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: A mechanism of tumor evasion
    • Zea AH, Rodriguez PC, Atkins MB et al.: Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: a mechanism of tumor evasion. Cancer Res. 65, 3044-3048 (2005).
    • (2005) Cancer Res. , vol.65 , pp. 3044-3048
    • Zea, A.H.1    Rodriguez, P.C.2    Atkins, M.B.3
  • 108
    • 34447258415 scopus 로고    scopus 로고
    • Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine
    • Filipazzi P, Valenti R, Huber V et al.: Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine. J. Clin. Oncol. 25, 2546-2553 (2007).
    • (2007) J. Clin. Oncol. , vol.25 , pp. 2546-2553
    • Filipazzi, P.1    Valenti, R.2    Huber, V.3
  • 109
    • 33846891555 scopus 로고    scopus 로고
    • Arginase, prostaglandins, and myeloid-derived suppressor cells in renal cell carcinoma
    • Ochoa AC, Zea AH, Hernandez C, Rodriguez PC: Arginase, prostaglandins, and myeloid-derived suppressor cells in renal cell carcinoma. Clin. Cancer Res. 13, 721S-726S (2007).
    • (2007) Clin. Cancer Res. , vol.13
    • Ochoa, A.C.1    Zea, A.H.2    Hernandez, C.3    Rodriguez, P.C.4
  • 110
    • 0037884830 scopus 로고    scopus 로고
    • Nitric oxide-independent CTL suppression during tumor progression: Association with arginase-producing (M2) myeloid cells
    • Liu Y, Van Ginderachter JA, Brys L, De Baetselier P, Raes G, Geldhof AB: Nitric oxide-independent CTL suppression during tumor progression: association with arginase-producing (M2) myeloid cells. J. Immunol. 170, 5064-5074 (2003).
    • (2003) J. Immunol. , Issue.170 , pp. 5064-5074
    • Liu, Y.1    Van Ginderachter, J.A.2    Brys, L.3    De Baetselier, P.4    Raes, G.5    Geldhof, A.B.6
  • 114
    • 10244279184 scopus 로고    scopus 로고
    • Mechanisms and functional significance of tumour-induced dendritic-cell defects
    • Gabrilovich D: Mechanisms and functional significance of tumour-induced dendritic-cell defects. Nat. Rev. Immunol. 4, 941-952 (2004).
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 941-952
    • Gabrilovich, D.1
  • 115
    • 0141456030 scopus 로고    scopus 로고
    • Myeloid cell expansion elicited by the progression of spontaneous mammary carcinomas in c-erbB-2 transgenic BALB/c mice suppresses immune reactivity
    • DOI 10.1182/blood-2003-01-0190
    • Melani C, Chiodoni C, Forni G, Colombo MP: Myeloid cell expansion elicited by the progression of spontaneous mammary carcinomas in c-erbB-2 transgenic BALB/c mice suppresses immune reactivity. Blood 102, 2138-2145 (2003). (Pubitemid 37122391)
    • (2003) Blood , vol.102 , Issue.6 , pp. 2138-2145
    • Melani, C.1    Chiodoni, C.2    Forni, G.3    Colombo, M.P.4
  • 116
    • 4344590947 scopus 로고    scopus 로고
    • High-dose granulocyte-macrophage colony-stimulating factor-producing vaccines impair the immune response through the recruitment of myeloid suppressor cells
    • DOI 10.1158/0008-5472.CAN-04-0757
    • Serafini P, Carbley R, Noonan KA, Tan G, Bronte V, Borrello I: High-dose granulocyte-macrophage colony-stimulating factor-producing vaccines impair the immune response through the recruitment of myeloid suppressor cells. Cancer Res. 64, 6337-6343 (2004). (Pubitemid 39129439)
    • (2004) Cancer Research , vol.64 , Issue.17 , pp. 6337-6343
    • Serafini, P.1    Carbley, R.2    Noonan, K.A.3    Tan, G.4    Bronte, V.5    Borrello, I.6
  • 117
    • 35448954376 scopus 로고    scopus 로고
    • Reduced inflammation in the tumor microenvironment delays the accumulation of myeloid-derived suppressor cells and limits tumor progression
    • DOI 10.1158/0008-5472.CAN-07-2354
    • Bunt SK, Yang L, Sinha P, Clements VK, Leips J, Ostrand-Rosenberg S: Reduced inflammation in the tumor microenvironment delays the accumulation of myeloid-derived suppressor cells and limits tumor progression. Cancer Res. 67, 10019-10026 (2007). (Pubitemid 47621253)
    • (2007) Cancer Research , vol.67 , Issue.20 , pp. 10019-10026
    • Bunt, S.K.1    Yang, L.2    Sinha, P.3    Clements, V.K.4    Leips, J.5    Ostrand-Rosenberg, S.6
  • 118
    • 34249300128 scopus 로고    scopus 로고
    • Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells
    • DOI 10.1158/0008-5472.CAN-06-4174
    • Sinha P, Clements VK, Fulton AM, Ostrand-Rosenberg S: Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells. Cancer Res. 67, 4507-4513 (2007). (Pubitemid 46815102)
    • (2007) Cancer Research , vol.67 , Issue.9 , pp. 4507-4513
    • Sinha, P.1    Clements, V.K.2    Fulton, A.M.3    Ostrand-Rosenberg, S.4
  • 120
    • 2642552399 scopus 로고    scopus 로고
    • Heparin-disaccharide affects T cells: Inhibition of NF-κB activation, cell migration, and modulation of intracellular signaling
    • Hecht I, Hershkoviz R, Shivtiel S et al.: Heparin-disaccharide affects T cells: inhibition of NF-κB activation, cell migration, and modulation of intracellular signaling. J. Leukoc. Biol. 75, 1139-1146 (2004).
    • (2004) J. Leukoc. Biol. , vol.75 , pp. 1139-1146
    • Hecht, I.1    Hershkoviz, R.2    Shivtiel, S.3
  • 122
    • 42249114676 scopus 로고    scopus 로고
    • Concentration-dependent roles for heparin in modifying lipopolysaccharide-induced activation of mononuclear cells in whole blood
    • Hochart H, Jenkins PV, Preston RJ, Smith OP, White B, O'Donnell J: Concentration-dependent roles for heparin in modifying lipopolysaccharide- induced activation of mononuclear cells in whole blood. Thromb. Haemost. 99, 570-575 (2008).
    • (2008) Thromb. Haemost. , vol.99 , pp. 570-575
    • Hochart, H.1    Jenkins, P.V.2    Preston, R.J.3    Smith, O.P.4    White, B.5    O'Donnell, J.6
  • 123
    • 34548585134 scopus 로고    scopus 로고
    • Modulatory effects of heparin and short-length oligosaccharides of heparin on the metastasis and growth of LMD MDA-MB 231 breast cancer cells in vivo
    • DOI 10.1038/sj.bjc.6603928, PII 6603928
    • Mellor P, Harvey JR, Murphy KJ et al.: Modulatory effects of heparin and short-length oligosaccharides of heparin on the metastasis and growth of LMD MDA-MB 231 breast cancer cells in vivo. Br. J. Cancer 97, 761-768 (2007). ■ Recent report demonstrating the effects of heparin on tumor growth and metastasis. (Pubitemid 47396282)
    • (2007) British Journal of Cancer , vol.97 , Issue.6 , pp. 761-768
    • Mellor, P.1    Harvey, J.R.2    Murphy, K.J.3    Pye, D.4    O'Boyle, G.5    Lennard, T.W.J.6    Kirby, J.A.7    Ali, S.8
  • 124
    • 33947410027 scopus 로고    scopus 로고
    • Inhibition of CXCR4-mediated breast cancer metastasis: A potential role for heparinoids?
    • DOI 10.1158/1078-0432.CCR-06-1987
    • Harvey JR, Mellor P, Eldaly H, Lennard TW, Kirby JA, Ali S: Inhibition of CXCR4-mediated breast cancer metastasis: a potential role for heparinoids? Clin. Cancer Res. 13, 1562-1570 (2007). (Pubitemid 46450448)
    • (2007) Clinical Cancer Research , vol.13 , Issue.5 , pp. 1562-1570
    • Harvey, J.R.1    Mellor, P.2    Eldaly, H.3    Lennard, T.W.J.4    Kirby, J.A.5    Ali, S.6
  • 125
    • 3042704507 scopus 로고    scopus 로고
    • Low molecular weight heparin, therapy with dalteparin, and survival in advanced cancer: The fragmin advanced malignancy outcome study (FAMOUS)
    • Kakkar AK, Levine MN, Kadziola Z et al.: Low molecular weight heparin, therapy with dalteparin, and survival in advanced cancer: the fragmin advanced malignancy outcome study (FAMOUS). J. Clin. Oncol. 22, 1944-1948 (2004).
    • (2004) J. Clin. Oncol. , vol.22 , pp. 1944-1948
    • Kakkar, A.K.1    Levine, M.N.2    Kadziola, Z.3
  • 126
    • 15244345079 scopus 로고    scopus 로고
    • The monomer-dimer equilibrium of stromal cell-derived factor-1 (CXCL 12) is altered by pH, phosphate, sulfate, and heparin
    • Veldkamp CT, Peterson FC, Pelzek AJ, Volkman BF: The monomer-dimer equilibrium of stromal cell-derived factor-1 (CXCL 12) is altered by pH, phosphate, sulfate, and heparin. Protein Sci. 14, 1071-1081 (2005).
    • (2005) Protein Sci. , vol.14 , pp. 1071-1081
    • Veldkamp, C.T.1    Peterson, F.C.2    Pelzek, A.J.3    Volkman, B.F.4
  • 127
    • 36749013634 scopus 로고    scopus 로고
    • Glycosaminoglycans and their synthetic mimetics inhibit RANTES-induced migration and invasion of human hepatoma cells
    • Sutton A, Friand V, Papy-Garcia D et al.: Glycosaminoglycans and their synthetic mimetics inhibit RANTES-induced migration and invasion of human hepatoma cells. Mol. Cancer Ther. 6, 2948-2958 (2007).
    • (2007) Mol. Cancer Ther. , vol.6 , pp. 2948-2958
    • Sutton, A.1    Friand, V.2    Papy-Garcia, D.3
  • 128
    • 0035815694 scopus 로고    scopus 로고
    • The BBXB motif of RANTES is the principal site for heparin binding and controls receptor selectivity
    • Proudfoot AE, Fritchley S, Borlat F et al.: The BBXB motif of RANTES is the principal site for heparin binding and controls receptor selectivity. J. Biol. Chem. 276, 10620-10626 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 10620-10626
    • Proudfoot, A.E.1    Fritchley, S.2    Borlat, F.3
  • 129
    • 33746473678 scopus 로고    scopus 로고
    • Simvastatin modulates chemokine and chemokine receptor expression by geranylgeranyl isoprenoid pathway in human endothelial cells and macrophages
    • DOI 10.1016/j.atherosclerosis.2005.10.015, PII S0021915005006660
    • Veillard NR, Braunersreuther V, Arnaud C et al.: Simvastatin modulates chemokine and chemokine receptor expression by geranylgeranyl isoprenoid pathway in human endothelial cells and macrophages. Atherosclerosis 188, 51-58 (2006). (Pubitemid 44142533)
    • (2006) Atherosclerosis , vol.188 , Issue.1 , pp. 51-58
    • Veillard, N.R.1    Braunersreuther, V.2    Arnaud, C.3    Burger, F.4    Pelli, G.5    Steffens, S.6    Mach, F.7
  • 130
    • 34250793265 scopus 로고    scopus 로고
    • Clinical importance and therapeutic implications of the pivotal CXCL12-CXCR4 (chemokine ligand-receptor) interaction in cancer cell migration
    • DOI 10.1159/000102979
    • Arya M, Ahmed H, Silhi N, Williamson M, Patel HR: Clinical importance and therapeutic implications of the pivotal CXCL12-CXCR4 (chemokine ligand-receptor) interaction in cancer cell migration. Tumour Biol. 28, 123-131 (2007). (Pubitemid 46975998)
    • (2007) Tumor Biology , vol.28 , Issue.3 , pp. 123-131
    • Arya, M.1    Ahmed, H.2    Silhi, N.3    Williamson, M.4    Patel, H.R.H.5
  • 131
    • 33846058844 scopus 로고    scopus 로고
    • The pivotal role of CXCL12 (SDF-1)/CXCR4 axis in bone metastasis
    • DOI 10.1007/s10555-006-9019-x, Special issue on Bone Metastasis and Cancer
    • Wang J, Loberg R, Taichman RS: The pivotal role of CXCL12 (SDF-1)/CXCR4 axis in bone metastasis. Cancer Metastasis Rev. 25, 573-587 (2006). (Pubitemid 46071864)
    • (2006) Cancer and Metastasis Reviews , vol.25 , Issue.4 , pp. 573-587
    • Wang, J.1    Loberg, R.2    Taichman, R.S.3
  • 133
    • 0344823964 scopus 로고    scopus 로고
    • A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors
    • Rubin JB, Kung AL, Klein RS et al.: A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors. Proc. Natl Acad. Sci. USA 100, 13513-13518 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 13513-13518
    • Rubin, J.B.1    Kung, A.L.2    Klein, R.S.3
  • 134
    • 37549044300 scopus 로고    scopus 로고
    • Biological role and potential therapeutic targeting of the chemokine receptor CXCR4 in undifferentiated thyroid cancer
    • De Falco V, Guarino V, Avilla E et al.: Biological role and potential therapeutic targeting of the chemokine receptor CXCR4 in undifferentiated thyroid cancer. Cancer Res. 67, 11821-11829 (2007).
    • (2007) Cancer Res. , vol.67 , pp. 11821-11829
    • De Falco, V.1    Guarino, V.2    Avilla, E.3
  • 135
  • 137
    • 34547634399 scopus 로고    scopus 로고
    • CXC chemokine receptor-4 antagonist blocks both growth of primary tumor and metastasis of head and neck cancer in xenograft mouse models
    • DOI 10.1158/0008-5472.CAN-06-2263
    • Yoon Y, Liang Z, Zhang X et al.: CXC chemokine receptor-4 antagonist blocks both growth of primary tumor and metastasis of head and neck cancer in xenograft mouse models. Cancer Res. 67, 7518-7524 (2007). (Pubitemid 47206582)
    • (2007) Cancer Research , vol.67 , Issue.15 , pp. 7518-7524
    • Yoon, Y.1    Liang, Z.2    Zhang, X.3    Choe, M.4    Zhu, A.5    Cho, H.T.6    Shin, D.M.7    Goodman, M.M.8    Chen, Z.9    Shim, H.10
  • 138
    • 35348855792 scopus 로고    scopus 로고
    • Small molecule CXCR4 chemokine receptor antagonists: Developing drug candidates
    • Khan A, Greenman J, Archibald SJ: Small molecule CXCR4 chemokine receptor antagonists: developing drug candidates. Curr. Med. Chem. 14, 2257-2277 (2007).
    • (2007) Curr. Med. Chem. , vol.14 , pp. 2257-2277
    • Khan, A.1    Greenman, J.2    Archibald, S.J.3
  • 140
    • 36148957078 scopus 로고    scopus 로고
    • Discovery of small molecule CXCR4 antagonists
    • Zhan W, Liang Z, Zhu A et al.: Discovery of small molecule CXCR4 antagonists. J. Med. Chem. 50, 5655-5664 (2007).
    • (2007) J. Med. Chem. , vol.50 , pp. 5655-5664
    • Zhan, W.1    Liang, Z.2    Zhu, A.3
  • 141
    • 42449111736 scopus 로고    scopus 로고
    • Inhibition of the CXCR4/CXCL12 chemokine pathway reduces the development of murine pulmonary metastases
    • Kim SY, Lee CH, Midura BV et al.: Inhibition of the CXCR4/CXCL12 chemokine pathway reduces the development of murine pulmonary metastases. Clin. Exp. Metastasis 25, 201-211 (2008).
    • (2008) Clin. Exp. Metastasis , vol.25 , pp. 201-211
    • Kim, S.Y.1    Lee, C.H.2    Midura, B.V.3
  • 142
    • 34250186076 scopus 로고    scopus 로고
    • Manipulating the chemokine-chemokine receptor network to treat cancer
    • DOI 10.1002/cncr.22706
    • Ruffini PA, Morandi P, Cabioglu N, Altundag K, Cristofanilli M: Manipulating the chemokine-chemokine receptor network to treat cancer. Cancer 109, 2392-2404 (2007). (Pubitemid 46906457)
    • (2007) Cancer , vol.109 , Issue.12 , pp. 2392-2404
    • Ruffini, P.A.1    Morandi, P.2    Cabioglu, N.3    Altundag, K.4    Cristofanilli, M.5
  • 143
  • 144
    • 0034111112 scopus 로고    scopus 로고
    • Macrophage inflammatory protein 3α transgene attracts dendritic cells to established murine tumors and suppresses tumor growth
    • Fushimi T, Kojima A, Moore MA, Crystal RG: Macrophage inflammatory protein 3α transgene attracts dendritic cells to established murine tumors and suppresses tumor growth. J. Clin. Invest. 105, 1383-1393 (2000).
    • (2000) J. Clin. Invest. , vol.105 , pp. 1383-1393
    • Fushimi, T.1    Kojima, A.2    Moore, M.A.3    Crystal, R.G.4
  • 145
    • 33645746888 scopus 로고    scopus 로고
    • Adenoviral gene transfer of stromal cell-derived factor-1 to murine tumors induces the accumulation of dendritic cells and suppresses tumor growth
    • Fushimi T, O'Connor TP, Crystal RG: Adenoviral gene transfer of stromal cell-derived factor-1 to murine tumors induces the accumulation of dendritic cells and suppresses tumor growth. Cancer Res. 66, 3513-3522 (2006).
    • (2006) Cancer Res. , vol.66 , pp. 3513-3522
    • Fushimi, T.1    O'Connor, T.P.2    Crystal, R.G.3
  • 146
    • 1842486876 scopus 로고    scopus 로고
    • Induction of potent antitumor immunity by in situ targeting of intratumoral DCs
    • Furumoto K, Soares L, Engleman EG, Merad M: Induction of potent antitumor immunity by in situ targeting of intratumoral DCs. J. Clin. Invest. 113, 774-783 (2004).
    • (2004) J. Clin. Invest. , vol.113 , pp. 774-783
    • Furumoto, K.1    Soares, L.2    Engleman, E.G.3    Merad, M.4
  • 148
    • 34249094199 scopus 로고    scopus 로고
    • CCL19 (ELC) as an adjuvant for DNA vaccination: Induction of a Th1-type T-cell response and enhancement of antitumor immunity
    • Westermann J, nguyen-Hoai T, Baldenhofer G et al.: CCL19 (ELC) as an adjuvant for DNA vaccination: induction of a Th1-type T-cell response and enhancement of antitumor immunity. Cancer Gene Ther. 14, 523-532 (2007).
    • (2007) Cancer Gene Ther. , vol.14 , pp. 523-532
    • Westermann, J.1    Nguyen-Hoai, T.2    Baldenhofer, G.3
  • 149
    • 0034254357 scopus 로고    scopus 로고
    • LEC induces Chemotaxis and adhesion by interacting with CCR1 and CCR8
    • Howard OM, Dong HF, Shirakawa AK, Oppenheim JJ: LEC induces Chemotaxis and adhesion by interacting with CCR1 and CCR8. Blood 96, 840-845 (2000).
    • (2000) Blood , vol.96 , pp. 840-845
    • Howard, O.M.1    Dong, H.F.2    Shirakawa, A.K.3    Oppenheim, J.J.4
  • 151
    • 1642326775 scopus 로고    scopus 로고
    • Intralesional Injection of Adenovirus Encoding CC Chemokine Ligand 16 Inhibits Mammary Tumor Growth and Prevents Metastatic-Induced Death after Surgical Removal of the Treated Primary Tumor
    • Guiducci C, Di Carlo E, Parenza M et al.: Intralesional injection of adenovirus encoding CC chemokine ligand 16 inhibits mammary tumor growth and prevents metastatic-induced death after surgical removal of the treated primary tumor. J. Immunol. 172, 4026-4036 (2004). (Pubitemid 38375214)
    • (2004) Journal of Immunology , vol.172 , Issue.7 , pp. 4026-4036
    • Guiducci, C.1    Di Carlo, E.2    Parenza, M.3    Hitt, M.4    Giovarelli, M.5    Musiani, P.6    Colombo, M.P.7
  • 152
    • 0034663955 scopus 로고    scopus 로고
    • Antitumor effects of the mouse chemokine 6chemokine/SLC through angiostatic and immunological mechanisms
    • Vicari AP, Ait-Yahia S, Chemin K, Mueller A, Zlotnik A, Caux C: Antitumor effects of the mouse chemokine 6chemokine/SLC through angiostatic and immunological mechanisms. J. Immunol. 165, 1992-2000 (2000).
    • (2000) J. Immunol. , vol.165 , pp. 1992-2000
    • Vicari, A.P.1    Ait-Yahia, S.2    Chemin, K.3    Mueller, A.4    Zlotnik, A.5    Caux, C.6
  • 154
    • 0035417890 scopus 로고    scopus 로고
    • Secondary lymphoid organ chemokine reduces pulmonary tumor burden in spontaneous murine bronchoalveolar cell carcinoma
    • Sharma S, Stolina M, Zhu L et al.: Secondary lymphoid organ chemokine reduces pulmonary tumor burden in spontaneous murine bronchoalveolar cell carcinoma. Cancer Res. 61, 6406-6412 (2001). (Pubitemid 32783246)
    • (2001) Cancer Research , vol.61 , Issue.17 , pp. 6406-6412
    • Sharma, S.1    Stolina, M.2    Zhu, L.3    Lin, Y.4    Batra, R.5    Huang, M.6    Strieter, R.7    Dubinett, S.M.8
  • 155
    • 33645531088 scopus 로고    scopus 로고
    • Intrapulmonary administration of CCL21 gene-modified dendritic cells reduces tumor burden in spontaneous murine bronchoalveolar cell carcinoma
    • Yang SC, Batra RK, Hillinger S et al.: Intrapulmonary administration of CCL21 gene-modified dendritic cells reduces tumor burden in spontaneous murine bronchoalveolar cell carcinoma. Cancer Res. 66, 3205-3213 (2006).
    • (2006) Cancer Res. , vol.66 , pp. 3205-3213
    • Yang, S.C.1    Batra, R.K.2    Hillinger, S.3
  • 156
    • 11144358381 scopus 로고    scopus 로고
    • Intratumoral administration of dendritic cells overexpressing CCL21 generates systemic antitumor responses and confers tumor immunity
    • Yang SC, Hillinger S, Riedl K et al.: Intratumoral administration of dendritic cells overexpressing CCL21 generates systemic antitumor responses and confers tumor immunity. Clin. Cancer Res. 10, 2891-2901 (2004).
    • (2004) Clin. Cancer Res. , vol.10 , pp. 2891-2901
    • Yang, S.C.1    Hillinger, S.2    Riedl, K.3
  • 157
    • 0036271492 scopus 로고    scopus 로고
    • Intratumoral coinjection of two adenoviral vectors expressing functional interleukin-18 and inducible protein-10, respectively, synergizes to facilitate regression of established tumors
    • DOI 10.1038/sj.cgt.7700466
    • Liu Y, Huang H, Saxena A, Xiang J: Intratumoral coinjection of two adenoviral vectors expressing functional interleukin-18 and inducible protein-10, respectively, synergizes to facilitate regression of established tumors. Cancer Gene Ther. 9, 533-542 (2002). (Pubitemid 34569036)
    • (2002) Cancer Gene Therapy , vol.9 , Issue.6 , pp. 533-542
    • Liu, Y.1    Huang, H.2    Saxena, A.3    Xiang, J.4
  • 158
    • 0034653833 scopus 로고    scopus 로고
    • Intratumoral coinjection of two adenoviruses, one encoding the chemokine IFN-γ-inducible protein-10 and another encoding IL-12, results in marked antitumoral synergy
    • Narvaiza I, Mazzolini G, Barajas M et al.: Intratumoral coinjection of two adenoviruses, one encoding the chemokine IFN-γ-inducible protein-10 and another encoding IL-12, results in marked antitumoral synergy. J. Immunol. 164, 3112-3122 (2000). (Pubitemid 30148972)
    • (2000) Journal of Immunology , vol.164 , Issue.6 , pp. 3112-3122
    • Narvaiza, I.1    Mazzolini, G.2    Barajas, M.3    Duarte, M.4    Zaratiegui, M.5    Qian, C.6    Melero, I.7    Prieto, J.8
  • 159
    • 0035085442 scopus 로고    scopus 로고
    • Combined CXC chemokine and interleukin-12 gene transfer enhances antitumor immunity
    • DOI 10.1038/sj.gt.3301386
    • Palmer K, Hitt M, Emtage PC, Gyorffy S, Gauldie J: Combined CXC chemokine and interleukin-12 gene transfer enhances antitumor immunity. Gene Ther. 8, 282-290 (2001). (Pubitemid 32237061)
    • (2001) Gene Therapy , vol.8 , Issue.4 , pp. 282-290
    • Palmer, K.1    Hitt, M.2    Emtage, P.C.R.3    Gyorffy, S.4    Gauldie, J.5
  • 160
    • 0029829106 scopus 로고    scopus 로고
    • Chemokine receptor specific for IP10 and MIG: Structure, function, and expression in activated T-lymphocytes
    • Loetscher M, Gerber B, Loetscher P et al.: Chemokine receptor specific for IP10 and MIG: structure, function, and expression in activated T-lymphocytes. J. Exp. Med. 184, 963-969 (1996).
    • (1996) J. Exp. Med. , vol.184 , pp. 963-969
    • Loetscher, M.1    Gerber, B.2    Loetscher, P.3
  • 161
    • 0027315862 scopus 로고
    • Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T cell adhesion to endothelial cells
    • Taub DD, Lloyd AR, Conlon K et al.: Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T cell adhesion to endothelial cells. J. Exp. Med. 177, 1809-1814 (1993).
    • (1993) J. Exp. Med. , vol.177 , pp. 1809-1814
    • Taub, D.D.1    Lloyd, A.R.2    Conlon, K.3
  • 162
    • 0029031790 scopus 로고
    • Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo
    • Angiolillo AL, Sgadari C, Taub DD et al.: Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo. J. Exp. Med. 182, 155-162 (1995).
    • (1995) J. Exp. Med. , vol.182 , pp. 155-162
    • Angiolillo, A.L.1    Sgadari, C.2    Taub, D.D.3
  • 163
    • 17144398046 scopus 로고    scopus 로고
    • Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection
    • Guiducci C, Vicari AP, Sangaletti S, Trinchieri G, Colombo MP: Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection. Cancer Res. 65, 3437-3446 (2005). (Pubitemid 40524630)
    • (2005) Cancer Research , vol.65 , Issue.8 , pp. 3437-3446
    • Guiducci, C.1    Vicari, A.P.2    Sangaletti, S.3    Trinchieri, G.4    Colombo, M.P.5
  • 164
    • 7044283134 scopus 로고    scopus 로고
    • Synergistic effect of lymphotactin and interferon γ-inducible protein-10 transgene expression in T-cell localization and adoptive T-cell therapy of tumors
    • DOI 10.1002/ijc.20043
    • Huang H, Xiang J: Synergistic effect of lymphotactin and interferon γ-inducible protein-10 transgene expression in T-cell localization and adoptive T-cell therapy of tumors. Int. J. Cancer 109, 817-825 (2004). (Pubitemid 38500737)
    • (2004) International Journal of Cancer , vol.109 , Issue.6 , pp. 817-825
    • Huang, H.1    Xiang, J.2
  • 165
    • 0033586324 scopus 로고    scopus 로고
    • Adenoviral vectors expressing lymphotactin and interleukin 2 or lymphotactin and interleukin 12 synergize to facilitate tumor regression in murine breast cancer models
    • Emtage PC, Wan Y, Hitt M et al.: Adenoviral vectors expressing lymphotactin and interleukin 2 or lymphotactin and interleukin 12 synergize to facilitate tumor regression in murine breast cancer models. Hum. Gene Ther. 10, 697-709 (1999).
    • (1999) Hum. Gene Ther. , vol.10 , pp. 697-709
    • Emtage, P.C.1    Wan, Y.2    Hitt, M.3
  • 166
    • 34548067624 scopus 로고    scopus 로고
    • Interleukin-12: Biological properties and clinical application
    • Del Vecchio M, Bajetta E, Canova S et al.: Interleukin-12: biological properties and clinical application. Clin. Cancer Res. 13, 4677-4685 (2007).
    • (2007) Clin. Cancer Res. , vol.13 , pp. 4677-4685
    • Del Vecchio, M.1    Bajetta, E.2    Canova, S.3
  • 168
    • 34247561214 scopus 로고    scopus 로고
    • Phase I trial of vaccination with autologous neuroblastoma tumor cells genetically modified to secrete IL-2 and lymphotactin
    • DOI 10.1097/01.cji.0000211335.14385.57, PII 0000237120070200000009
    • Russell HV, Strother D, Mei Z et al.: Phase I trial of vaccination with autologous neuroblastoma tumor cells genetically modified to secrete IL-2 and lymphotactin. J. Immunother. 30, 227-233 (2007). (Pubitemid 46667802)
    • (2007) Journal of Immunotherapy , vol.30 , Issue.2 , pp. 227-233
    • Russell, H.V.1    Strother, D.2    Mei, Z.3    Rill, D.4    Popek, E.5    Biagi, E.6    Yvon, E.7    Brenner, M.8    Rousseau, R.9
  • 169
    • 0036428790 scopus 로고    scopus 로고
    • Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2
    • Kershaw MH, Wang G, Westwood JA et al.: Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2. Hum. Gene Ther. 13, 1971-1980 (2002).
    • (2002) Hum. Gene Ther. , vol.13 , pp. 1971-1980
    • Kershaw, M.H.1    Wang, G.2    Westwood, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.