Nitroaspirin corrects immune dysfunction in tumor-bearing hosts and promotes tumor eradication by cancer vaccination

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 11, 2005, Pages 4185-4190

  De Santo, Carmela ^a   Serafini, Paolo ^a,e   Marigo, Ilaria ^a   Dolcetti, Luigi ^a   Bolla, Manlio ^b   Del Soldato, Piero ^b   Melani, Cecilia ^c   Guiducci, Cristiana ^c   Colombo, Mario P ^c   Iezzi, Manuela ^d   Musiani, Piero ^d   Zanovello, Paola ^a   Bronte, Vincenzo ^a,f  

^a Oncology Section   (Italy)

^b NicOx SA   (France)

^c NATIONAL CANCER INSTITUTE   (Italy)

^d UNIVERSITY OF CHIETI   (Italy)

^e JOHNS HOPKINS UNIVERSITY   (United States)

^f UNIVERSITY OF PADOVA   (Italy)

Author keywords

Arginase; Immunosuppression; Immunotherapy; Myeloid cells; Nitric oxide

Indexed keywords

2(ACETYLOXY)BENZOIC ACID 2(NITROOXYMETHYL)PHENYL ESTER; 2(ACETYLOXY)BENZOIC ACID 3(HYDROXYMETHYL)PHENYL ESTER; ACETYLSALICYLIC ACID; ACETYLSALICYLIC ACID 3 (NITROXYMETHYL)PHENYL ESTER; ACETYLSALICYLIC ACID DERIVATIVE; ARGINASE; CANCER VACCINE; NCX 4017; NCX 4060; NITRIC OXIDE; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BONE MARROW CELL; CANCER IMMUNIZATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOTHERAPY; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; TUMOR IMMUNITY;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; CANCER VACCINES; CARRIER PROTEINS; IMMUNE SYSTEM DISEASES; MICE; MICE, INBRED BALB C; NEOPLASM PROTEINS; NEOPLASMS; NITRIC OXIDE SYNTHASE; T-LYMPHOCYTES; TIME FACTORS;

EID: 20144375187     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0409783102     Document Type: Article

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