-
1
-
-
0029924107
-
Human tumor antigens recognized by T lymphocytes
-
Boon, T., and van der Bruggen, P. 1996. Human tumor antigens recognized by T lymphocytes. J. Exp. Med. 183:725-729.
-
(1996)
J. Exp. Med
, vol.183
, pp. 725-729
-
-
Boon, T.1
van der Bruggen, P.2
-
2
-
-
27644534576
-
The response of autologous T cells to a human melanoma is dominated by mutated neoantigens
-
Lennerz, V., et al. 2005. The response of autologous T cells to a human melanoma is dominated by mutated neoantigens. Proc. Natl. Acad. Sci. U. S. A. 102:16013-16018.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A
, vol.102
, pp. 16013-16018
-
-
Lennerz, V.1
-
3
-
-
30044438884
-
Processing and presentation of tumor antigens and vaccination strategies
-
van der Bruggen, P., and van den Eynde, B.J. 2006. Processing and presentation of tumor antigens and vaccination strategies. Curr. Opin. Immunol. 18:98-104.
-
(2006)
Curr. Opin. Immunol
, vol.18
, pp. 98-104
-
-
van der Bruggen, P.1
van den Eynde, B.J.2
-
4
-
-
21144454780
-
Recruitment of latent pools of high-avidity CD8(+) T cells to the antitumor immune response
-
Ercolini, A.M., et al. 2005. Recruitment of latent pools of high-avidity CD8(+) T cells to the antitumor immune response. J. Exp. Med. 201:1591-1602.
-
(2005)
J. Exp. Med
, vol.201
, pp. 1591-1602
-
-
Ercolini, A.M.1
-
5
-
-
0033514923
-
Immune surveillance against a solid tumor fails because of immunological ignorance
-
Ochsenbein, A.F., et al. 1999. Immune surveillance against a solid tumor fails because of immunological ignorance. Proc. Natl. Acad. Sci. U. S. A. 96:2233-2238.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A
, vol.96
, pp. 2233-2238
-
-
Ochsenbein, A.F.1
-
6
-
-
0036911269
-
Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells
-
Spiotto, M.T., et al. 2002. Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells. Immunity. 17:737-747.
-
(2002)
Immunity
, vol.17
, pp. 737-747
-
-
Spiotto, M.T.1
-
7
-
-
0035883073
-
Cross-presentation of tumor antigens by bone marrow-derived antigen-presenting cells is the dominant mechanism in the induction of T-cell tolerance during B-cell lymphoma progression
-
Sotomayor, E.M., et al. 2001. Cross-presentation of tumor antigens by bone marrow-derived antigen-presenting cells is the dominant mechanism in the induction of T-cell tolerance during B-cell lymphoma progression. Blood. 98:1070-1077.
-
(2001)
Blood
, vol.98
, pp. 1070-1077
-
-
Sotomayor, E.M.1
-
8
-
-
15444377017
-
Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors
-
Yu, P., et al. 2005. Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors. J. Exp. Med. 201:779-791.
-
(2005)
J. Exp. Med
, vol.201
, pp. 779-791
-
-
Yu, P.1
-
9
-
-
30444443314
-
Amplification of tumor-specific regulatory T cells following therapeutic cancer vaccines
-
Zhou, G., Drake, C.G., and Levitsky, H.I. 2006. Amplification of tumor-specific regulatory T cells following therapeutic cancer vaccines. Blood. 107:628-636.
-
(2006)
Blood
, vol.107
, pp. 628-636
-
-
Zhou, G.1
Drake, C.G.2
Levitsky, H.I.3
-
10
-
-
33747188614
-
Antigen targeting to endosomal pathway in dendritic cell vaccination activates regulatory T cells and attenuates tumor immunity
-
Maksimow, M., Miiluniemi, M., Marttila-Ichihara, F., Jalkanen, S., and Hanninen, A. 2006. Antigen targeting to endosomal pathway in dendritic cell vaccination activates regulatory T cells and attenuates tumor immunity. Blood. 108:1298-1305.
-
(2006)
Blood
, vol.108
, pp. 1298-1305
-
-
Maksimow, M.1
Miiluniemi, M.2
Marttila-Ichihara, F.3
Jalkanen, S.4
Hanninen, A.5
-
11
-
-
16844379997
-
Immunosuppressive networks in the tumour environment and their therapeutic relevance
-
Zou, W. 2005. Immunosuppressive networks in the tumour environment and their therapeutic relevance. Nat. Rev. Cancer. 5:263-274.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 263-274
-
-
Zou, W.1
-
12
-
-
0036690151
-
Endogenous kynurenines as targets for drug discovery and development
-
Stone, T.W., and Darlington, L.G. 2002. Endogenous kynurenines as targets for drug discovery and development. Nat. Rev. Drug Discov. 1:609-620.
-
(2002)
Nat. Rev. Drug Discov
, vol.1
, pp. 609-620
-
-
Stone, T.W.1
Darlington, L.G.2
-
13
-
-
31044446342
-
Monitoring tryptophan metabolism in chronic immune activation
-
Schrocksnadel, K., Wirleitner, B., Winkler, C., and Fuchs, D. 2006. Monitoring tryptophan metabolism in chronic immune activation. Clin. Chim. Acta. 364:82-90.
-
(2006)
Clin. Chim. Acta
, vol.364
, pp. 82-90
-
-
Schrocksnadel, K.1
Wirleitner, B.2
Winkler, C.3
Fuchs, D.4
-
14
-
-
0037024439
-
Serum tryptophan decrease correlates with immune activation and impaired quality of life in colorectal cancer
-
Huang, A., et al. 2002. Serum tryptophan decrease correlates with immune activation and impaired quality of life in colorectal cancer. Br. J. Cancer. 86:1691-1696.
-
(2002)
Br. J. Cancer
, vol.86
, pp. 1691-1696
-
-
Huang, A.1
-
15
-
-
33748749786
-
Immune privilege in the gut: The establishment and maintenance of non-responsiveness to dietary antigens and commensal flora
-
Iweala, O.I., and Nagler, C.R. 2006. Immune privilege in the gut: the establishment and maintenance of non-responsiveness to dietary antigens and commensal flora. Immunol. Rev. 213:82-100.
-
(2006)
Immunol. Rev
, vol.213
, pp. 82-100
-
-
Iweala, O.I.1
Nagler, C.R.2
-
16
-
-
0032555614
-
Prevention of allogeneic fetal rejection by tryptophan catabolism
-
Munn, D.H., et al. 1998. Prevention of allogeneic fetal rejection by tryptophan catabolism. Science. 281:1191-1193.
-
(1998)
Science
, vol.281
, pp. 1191-1193
-
-
Munn, D.H.1
-
17
-
-
0035221101
-
Prevention of T cell-driven complement activation and inflammation by tryptophan catabolism during pregnancy
-
Mellor, A.L., et al. 2001. Prevention of T cell-driven complement activation and inflammation by tryptophan catabolism during pregnancy. Nat. Immunol. 2:64-68.
-
(2001)
Nat. Immunol
, vol.2
, pp. 64-68
-
-
Mellor, A.L.1
-
18
-
-
16244408626
-
Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy
-
Muller, A.J., Duhadaway, J.B., Donover, P.S., Sutanto-Ward, E., and Prendergast, G.C. 2005. Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy. Nat. Med. 11:312-319.
-
(2005)
Nat. Med
, vol.11
, pp. 312-319
-
-
Muller, A.J.1
Duhadaway, J.B.2
Donover, P.S.3
Sutanto-Ward, E.4
Prendergast, G.C.5
-
19
-
-
0036852170
-
CTLA-4-Ig regulates tryptophan catabolism in vivo
-
Grohmann, U., et al. 2002. CTLA-4-Ig regulates tryptophan catabolism in vivo. Nat. Immunol. 3:1097-1101.
-
(2002)
Nat. Immunol
, vol.3
, pp. 1097-1101
-
-
Grohmann, U.1
-
20
-
-
0042591467
-
Cutting edge: Induced indoleamine 2,3 dioxygenase expression in dendritic cell subsets suppresses T cell clonal expansion
-
Mellor, A.L., et al. 2003. Cutting edge: Induced indoleamine 2,3 dioxygenase expression in dendritic cell subsets suppresses T cell clonal expansion. J. Immunol. 171:1652-1655.
-
(2003)
J. Immunol
, vol.171
, pp. 1652-1655
-
-
Mellor, A.L.1
-
21
-
-
33751193093
-
Indoleamine 2,3-dioxygenase (IDO) is involved in promoting the development of anterior chamber-associated immune deviation
-
Chen, X., et al. 2006. Indoleamine 2,3-dioxygenase (IDO) is involved in promoting the development of anterior chamber-associated immune deviation. Immunol. Lett. 107:140-147.
-
(2006)
Immunol. Lett
, vol.107
, pp. 140-147
-
-
Chen, X.1
-
22
-
-
0345490963
-
Inhibition of indoleamine 2,3-dioxygenase augments trinitrobenzene sulfonic acid colitis in mice
-
Gurtner, G.J., Newberry, R.D., Schloemann, S.R., McDonald, K.G., and Stenson, W.F. 2003. Inhibition of indoleamine 2,3-dioxygenase augments trinitrobenzene sulfonic acid colitis in mice. Gastroenterology. 125:1762-1773.
-
(2003)
Gastroenterology
, vol.125
, pp. 1762-1773
-
-
Gurtner, G.J.1
Newberry, R.D.2
Schloemann, S.R.3
McDonald, K.G.4
Stenson, W.F.5
-
23
-
-
23444449846
-
Indolamine 2,3-dioxygenase is expressed in the CNS and downregulates autoimmune inflammation
-
Kwidzinski, E., et al. 2005. Indolamine 2,3-dioxygenase is expressed in the CNS and downregulates autoimmune inflammation. FASEB J. 19:1347-1349.
-
(2005)
FASEB J
, vol.19
, pp. 1347-1349
-
-
Kwidzinski, E.1
-
24
-
-
4043170040
-
Inhibition of experimental asthma by indoleamine 2,3-dioxygenase
-
doi:10.1172/JCI200421275
-
Hayashi, T., et al. 2004. Inhibition of experimental asthma by indoleamine 2,3-dioxygenase. J. Clin. Invest. 114:270-279. doi:10.1172/JCI200421275.
-
(2004)
J. Clin. Invest
, vol.114
, pp. 270-279
-
-
Hayashi, T.1
-
25
-
-
1542374723
-
CDIIc+ cells modulate pulmonary immune responses by production of indoleamine 2,3-dioxygenase
-
Swanson, K.A., Zheng, Y., Heidler, K.M., Mizobuchi, T., and Wilkes, D.S. 2004. CDIIc+ cells modulate pulmonary immune responses by production of indoleamine 2,3-dioxygenase. Am. J. Respir. Cell Mol. Biol. 30:311-318.
-
(2004)
Am. J. Respir. Cell Mol. Biol
, vol.30
, pp. 311-318
-
-
Swanson, K.A.1
Zheng, Y.2
Heidler, K.M.3
Mizobuchi, T.4
Wilkes, D.S.5
-
26
-
-
33845599867
-
Sleeping Beauty-based gene therapy with indoleamine 2,3-dioxygenase inhibits lung allograft fibrosis
-
Liu, H., Liu, L., Fletcher, B.S., and Visner, G.A. 2006. Sleeping Beauty-based gene therapy with indoleamine 2,3-dioxygenase inhibits lung allograft fibrosis. FASEB J. 20:2384-2386.
-
(2006)
FASEB J
, vol.20
, pp. 2384-2386
-
-
Liu, H.1
Liu, L.2
Fletcher, B.S.3
Visner, G.A.4
-
27
-
-
33644955010
-
Function of indoleamine 2,3-dioxygenase in corneal allograft rejection and prolongation of allograft survival by overexpression
-
Beutelspacher, S.C., et al. 2006. Function of indoleamine 2,3-dioxygenase in corneal allograft rejection and prolongation of allograft survival by overexpression. Eur. J. Immunol. 36:690-700.
-
(2006)
Eur. J. Immunol
, vol.36
, pp. 690-700
-
-
Beutelspacher, S.C.1
-
28
-
-
0142137237
-
Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase
-
Uyttenhove, C., et al. 2003. Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase. Nat. Med. 9:1269-1274.
-
(2003)
Nat. Med
, vol.9
, pp. 1269-1274
-
-
Uyttenhove, C.1
-
29
-
-
4043092238
-
Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes
-
doi:10.1172/JCI200421583
-
Munn, D.H., et al. 2004. Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes. J. Clin. Invest. 114:280-290. doi:10.1172/JCI200421583.
-
(2004)
J. Clin. Invest
, vol.114
, pp. 280-290
-
-
Munn, D.H.1
-
30
-
-
0035879111
-
IL-6 inhibits the tolerogenic function of CD8alpha(+) dendritic cells expressing indoleamine 2,3-dioxygenase
-
Grohmann, U., et al. 2001. IL-6 inhibits the tolerogenic function of CD8alpha(+) dendritic cells expressing indoleamine 2,3-dioxygenase. J. Immunol. 167:708-714.
-
(2001)
J. Immunol
, vol.167
, pp. 708-714
-
-
Grohmann, U.1
-
31
-
-
33645499663
-
Toward the identification of a tolerogenic signature in IDO-competent dendritic cells
-
Orabona, C., et al. 2006. Toward the identification of a tolerogenic signature in IDO-competent dendritic cells. Blood. 107:2846-2854.
-
(2006)
Blood
, vol.107
, pp. 2846-2854
-
-
Orabona, C.1
-
32
-
-
18544364477
-
Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase
-
Munn, D.H., et al. 2002. Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase. Science. 297:1867-1870.
-
(2002)
Science
, vol.297
, pp. 1867-1870
-
-
Munn, D.H.1
-
33
-
-
1642396607
-
Ligation of B7-1/B7-2 by human CD4+ T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells
-
Munn, D.H., Sharma, M.D., and Mellor, A.L. 2004. Ligation of B7-1/B7-2 by human CD4+ T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells. J. Immunol. 172:4100-4110.
-
(2004)
J. Immunol
, vol.172
, pp. 4100-4110
-
-
Munn, D.H.1
Sharma, M.D.2
Mellor, A.L.3
-
34
-
-
0042930935
-
Functional plasticity of dendritic cell subsets as mediated by CD40 versus B7 activation
-
Grohmann, U., et al. 2003. Functional plasticity of dendritic cell subsets as mediated by CD40 versus B7 activation. J. Immunol. 171:2581-2587.
-
(2003)
J. Immunol
, vol.171
, pp. 2581-2587
-
-
Grohmann, U.1
-
35
-
-
27144476792
-
A two step induction of indoleamine 2,3 dioxygenase (IDO) activity during dendritic cell maturation
-
Braun, D., Longman, R.S., and Albert, M.L. 2005. A two step induction of indoleamine 2,3 dioxygenase (IDO) activity during dendritic cell maturation. Blood. 106:2375-2381.
-
(2005)
Blood
, vol.106
, pp. 2375-2381
-
-
Braun, D.1
Longman, R.S.2
Albert, M.L.3
-
36
-
-
33745622659
-
CD25 and indoleamine 2,3-dioxygenase are up-regulated by prostaglandin E2 and expressed by tumor-associated dendritic cells in vivo: Additional mechanisms of T-cell inhibition
-
von Bergwelt-Baildon, M.S., et al. 2006. CD25 and indoleamine 2,3-dioxygenase are up-regulated by prostaglandin E2 and expressed by tumor-associated dendritic cells in vivo: additional mechanisms of T-cell inhibition. Blood. 108:228-237.
-
(2006)
Blood
, vol.108
, pp. 228-237
-
-
von Bergwelt-Baildon, M.S.1
-
37
-
-
0025944659
-
Relationship between interferon-γ, indoleamine 2,3-dioxygenase, and tryptophan catabolism
-
Taylor, M.W., and Feng, G. 1991. Relationship between interferon-γ, indoleamine 2,3-dioxygenase, and tryptophan catabolism. FASEB J. 5:2516-2522.
-
(1991)
FASEB J
, vol.5
, pp. 2516-2522
-
-
Taylor, M.W.1
Feng, G.2
-
38
-
-
0036790338
-
T cell apoptosis by tryptophan catabolism
-
Fallarino, F., et al. 2002. T cell apoptosis by tryptophan catabolism. Cell Death Differ. 9:1069-1077.
-
(2002)
Cell Death Differ
, vol.9
, pp. 1069-1077
-
-
Fallarino, F.1
-
39
-
-
0037136328
-
Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2,3-dioxygenase
-
Frumento, G., et al. 2002. Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2,3-dioxygenase. J. Exp. Med. 196:459-468.
-
(2002)
J. Exp. Med
, vol.196
, pp. 459-468
-
-
Frumento, G.1
-
40
-
-
0037136266
-
Inhibition of allogeneic T cell proliferation by indoleamine 2,3-dioxygenase-expressing dendritic cells: Mediation of suppression by tryptophan metabolites
-
Terness, P., et al. 2002. Inhibition of allogeneic T cell proliferation by indoleamine 2,3-dioxygenase-expressing dendritic cells: mediation of suppression by tryptophan metabolites. J. Exp. Med. 196:447-457.
-
(2002)
J. Exp. Med
, vol.196
, pp. 447-457
-
-
Terness, P.1
-
41
-
-
32944468867
-
Differential effects of the tryptophan metabolite 3-hydroxyanthranilic acid on the proliferation of human CD8+ T cells induced by TCR triggering or homeostatic cytokines
-
Weber, W.P., et al. 2006. Differential effects of the tryptophan metabolite 3-hydroxyanthranilic acid on the proliferation of human CD8+ T cells induced by TCR triggering or homeostatic cytokines. Eur. J. Immunol. 36:296-304.
-
(2006)
Eur. J. Immunol
, vol.36
, pp. 296-304
-
-
Weber, W.P.1
-
42
-
-
33750699056
-
The tryptophan catabolite L-kynurenine inhibits the surface expression of NKp46- and NKG2D-activating receptors and regulates NK-cell function
-
Chiesa, M.D., et al. 2006. The tryptophan catabolite L-kynurenine inhibits the surface expression of NKp46- and NKG2D-activating receptors and regulates NK-cell function. Blood. 108:4118-4125.
-
(2006)
Blood
, vol.108
, pp. 4118-4125
-
-
Chiesa, M.D.1
-
43
-
-
33745304367
-
Kynurenine pathway enzymes in dendritic cells initiate tolerogenesis in the absence of functional IDO
-
Belladonna, M.L., et al. 2006. Kynurenine pathway enzymes in dendritic cells initiate tolerogenesis in the absence of functional IDO. J. Immunol. 177:130-137.
-
(2006)
J. Immunol
, vol.177
, pp. 130-137
-
-
Belladonna, M.L.1
-
44
-
-
21244487758
-
Studying the immunosuppressive role of indoleamine 2,3-dioxygenase: Tryptophan metabolites suppress rat allogeneic T-cell responses in vitro and in vivo
-
Bauer, T.M., et al. 2005. Studying the immunosuppressive role of indoleamine 2,3-dioxygenase: tryptophan metabolites suppress rat allogeneic T-cell responses in vitro and in vivo. Transpl. Int. 18:95-100.
-
(2005)
Transpl. Int
, vol.18
, pp. 95-100
-
-
Bauer, T.M.1
-
45
-
-
27644587079
-
Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite
-
Platten, M., et al. 2005. Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite. Science. 310:850-855.
-
(2005)
Science
, vol.310
, pp. 850-855
-
-
Platten, M.1
-
46
-
-
33746823331
-
Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35
-
Wang, J., et al. 2006. Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35. J. Biol. Chem. 281:22021-22028.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 22021-22028
-
-
Wang, J.1
-
47
-
-
0037101793
-
Fc-gamma RI induces the tryptophan degradation pathway involved in regulating T cell responses
-
Bubnoff, D., et al. 2002. Fc-gamma RI induces the tryptophan degradation pathway involved in regulating T cell responses. J. Immunol. 169:1810-1816.
-
(2002)
J. Immunol
, vol.169
, pp. 1810-1816
-
-
Bubnoff, D.1
-
48
-
-
19344377474
-
GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase
-
Munn, D.H., et al. 2005. GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase. Immunity. 22:633-642.
-
(2005)
Immunity
, vol.22
, pp. 633-642
-
-
Munn, D.H.1
-
49
-
-
33646893538
-
The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cells
-
Fallarino, F., et al. 2006. The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cells. J. Immunol. 176:6752- 6761.
-
(2006)
J. Immunol
, vol.176
, pp. 6752-6761
-
-
Fallarino, F.1
-
50
-
-
0033635215
-
Uncharged tRNA activates GCN2 by displacing the protein kinase moiety from a bipartite tRNA-binding domain
-
Dong, J., Qiu, H., Garcia-Barrio, M., Anderson, J., and Hinnebusch, A.G. 2000. Uncharged tRNA activates GCN2 by displacing the protein kinase moiety from a bipartite tRNA-binding domain. Mol. Cell. 6:269-279.
-
(2000)
Mol. Cell
, vol.6
, pp. 269-279
-
-
Dong, J.1
Qiu, H.2
Garcia-Barrio, M.3
Anderson, J.4
Hinnebusch, A.G.5
-
51
-
-
0037353039
-
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
-
Harding, H.P., et al. 2003. An integrated stress response regulates amino acid metabolism and resistance to oxidative stress. Mol. Cell. 11:619-633.
-
(2003)
Mol. Cell
, vol.11
, pp. 619-633
-
-
Harding, H.P.1
-
52
-
-
32544446451
-
Coping with stress: EIF2 kinases and translational control
-
Wek, R.C., Jiang, H.Y., and Anthony, T.G. 2006. Coping with stress: eIF2 kinases and translational control. Biochem. Soc. Trans. 34:7-11.
-
(2006)
Biochem. Soc. Trans
, vol.34
, pp. 7-11
-
-
Wek, R.C.1
Jiang, H.Y.2
Anthony, T.G.3
-
53
-
-
0032477815
-
Induction of antigen-specific T cell anergy: An early event in the course of tumor progression
-
Staveley-O'Carroll, K., et al. 1998. Induction of antigen-specific T cell anergy: an early event in the course of tumor progression. Proc. Natl. Acad. Sci. U. S. A. 95:1178-1183.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A
, vol.95
, pp. 1178-1183
-
-
Staveley-O'Carroll, K.1
-
54
-
-
9144274980
-
Extra-lymphatic solid tumor growth is not immunologically ignored and results in early induction of antigen-specific T-cell anergy: Dominant role of cross-tolerance to tumor antigens
-
Cuenca, A., et al. 2003. Extra-lymphatic solid tumor growth is not immunologically ignored and results in early induction of antigen-specific T-cell anergy: dominant role of cross-tolerance to tumor antigens. Cancer Res. 63:9007-9015.
-
(2003)
Cancer Res
, vol.63
, pp. 9007-9015
-
-
Cuenca, A.1
-
55
-
-
33748749338
-
Immune resistance orchestrated by the tumor microenvironment
-
Gajewski, T.F., et al. 2006. Immune resistance orchestrated by the tumor microenvironment. Immunol. Rev. 213:131-145.
-
(2006)
Immunol. Rev
, vol.213
, pp. 131-145
-
-
Gajewski, T.F.1
-
56
-
-
33645286546
-
Regulatory T cells, tumour immunity and immunotherapy
-
Zou, W. 2006. Regulatory T cells, tumour immunity and immunotherapy. Nat. Rev. Immunol. 6:295-307.
-
(2006)
Nat. Rev. Immunol
, vol.6
, pp. 295-307
-
-
Zou, W.1
-
57
-
-
0028179056
-
Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens
-
Huang, A.Y., et al. 1994. Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens. Science. 264:961-965.
-
(1994)
Science
, vol.264
, pp. 961-965
-
-
Huang, A.Y.1
-
58
-
-
0037460070
-
Complementary role of CD4+ T cells and secondary lymphoid tissues for cross-presentation of tumor antigen to CD8+ T cells
-
Yu, P., Spiotto, M.T., Lee, Y., Schreiber, H., and Fu, Y.X. 2003. Complementary role of CD4+ T cells and secondary lymphoid tissues for cross-presentation of tumor antigen to CD8+ T cells. J. Exp. Med. 197:985-995.
-
(2003)
J. Exp. Med
, vol.197
, pp. 985-995
-
-
Yu, P.1
Spiotto, M.T.2
Lee, Y.3
Schreiber, H.4
Fu, Y.X.5
-
59
-
-
9144261696
-
Activation of dendritic cells that cross-present tumor-derived antigen licenses CD8+ CTL to cause tumor eradication
-
van Mierlo, G., et al. 2004. Activation of dendritic cells that cross-present tumor-derived antigen licenses CD8+ CTL to cause tumor eradication. J. Immunol. 173:6753-6759.
-
(2004)
J. Immunol
, vol.173
, pp. 6753-6759
-
-
van Mierlo, G.1
-
60
-
-
0038326676
-
Induction of tumor cell apoptosis in vivo increases tumor antigen cross-presentation, cross-priming rather than cross-tolerizing host tumor-specific CD8 T cells
-
Nowak, A.K., et al. 2003. Induction of tumor cell apoptosis in vivo increases tumor antigen cross-presentation, cross-priming rather than cross-tolerizing host tumor-specific CD8 T cells. J. Immunol. 170:4905-4913.
-
(2003)
J. Immunol
, vol.170
, pp. 4905-4913
-
-
Nowak, A.K.1
-
61
-
-
33750354371
-
Incomplete differentiation of antigen-specific CD8 T cells in tumor-draining lymph nodes
-
Hargadon, K.M., et al. 2006. Incomplete differentiation of antigen-specific CD8 T cells in tumor-draining lymph nodes. J. Immunol. 177:6081-6090.
-
(2006)
J. Immunol
, vol.177
, pp. 6081-6090
-
-
Hargadon, K.M.1
-
62
-
-
0042696999
-
Antigen presentation to naive CD4 T cells in the lymph node
-
Itano, A.A., and Jenkins, M.K. 2003. Antigen presentation to naive CD4 T cells in the lymph node. Nat. Immunol. 4:733-739.
-
(2003)
Nat. Immunol
, vol.4
, pp. 733-739
-
-
Itano, A.A.1
Jenkins, M.K.2
-
63
-
-
25144452923
-
Continuous control of autoimmune disease by antigen-dependent polyclonal CD4+CD25+ regulatory T cells in the regional lymph node
-
Samy, E.T., Parker, L.A., Sharp, C.P., and Tung, K.S. 2005. Continuous control of autoimmune disease by antigen-dependent polyclonal CD4+CD25+ regulatory T cells in the regional lymph node. J. Exp. Med. 202:771-781.
-
(2005)
J. Exp. Med
, vol.202
, pp. 771-781
-
-
Samy, E.T.1
Parker, L.A.2
Sharp, C.P.3
Tung, K.S.4
-
64
-
-
0036196305
-
Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: Highly potent regulators of diabetes that require TRANCE-RANK signals
-
Green, E.A., Choi, Y., and Flavell, R.A. 2002. Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signals. Immunity. 16:183-191.
-
(2002)
Immunity
, vol.16
, pp. 183-191
-
-
Green, E.A.1
Choi, Y.2
Flavell, R.A.3
-
65
-
-
0033557738
-
Intranasally induced immunological tolerance is determined by characteristics of the draining lymph nodes: Studies with OVA and human cartilage gp-39
-
Wolvers, D.A., et al. 1999. Intranasally induced immunological tolerance is determined by characteristics of the draining lymph nodes: studies with OVA and human cartilage gp-39. J. Immunol. 162:1994-1998.
-
(1999)
J. Immunol
, vol.162
, pp. 1994-1998
-
-
Wolvers, D.A.1
-
66
-
-
33748754933
-
The importance of regional lymph nodes for mucosal tolerance
-
Kraal, G., Samsom, J.N., and Mebius, R.E. 2006. The importance of regional lymph nodes for mucosal tolerance. Immunol. Rev. 213:119-130.
-
(2006)
Immunol. Rev
, vol.213
, pp. 119-130
-
-
Kraal, G.1
Samsom, J.N.2
Mebius, R.E.3
-
67
-
-
33748750776
-
The tumor-draining lymph node as an immune-privileged site
-
Munn, D.H., and Mellor, A.L. 2006. The tumor-draining lymph node as an immune-privileged site. Immunol. Rev. 213:146-158.
-
(2006)
Immunol. Rev
, vol.213
, pp. 146-158
-
-
Munn, D.H.1
Mellor, A.L.2
-
68
-
-
33748076467
-
Tumour-induced immune modulation of sentinel lymph nodes
-
Cochran, A.J., et al. 2006. Tumour-induced immune modulation of sentinel lymph nodes. Nat. Rev. Immunol. 6:659-670.
-
(2006)
Nat. Rev. Immunol
, vol.6
, pp. 659-670
-
-
Cochran, A.J.1
-
69
-
-
0142011214
-
Pattern of recruitment of immunoregulatory antigen presenting cells in malignant melanoma
-
Lee, J.R., et al. 2003. Pattern of recruitment of immunoregulatory antigen presenting cells in malignant melanoma. Lab. Invest. 83:1457-1466.
-
(2003)
Lab. Invest
, vol.83
, pp. 1457-1466
-
-
Lee, J.R.1
-
70
-
-
11344249225
-
Quantitative analysis of melanoma-induced cytokine-mediated immunosuppression in melanoma sentinel nodes
-
Lee, J.H., et al. 2005. Quantitative analysis of melanoma-induced cytokine-mediated immunosuppression in melanoma sentinel nodes. Clin. Cancer Res. 11:107-112.
-
(2005)
Clin. Cancer Res
, vol.11
, pp. 107-112
-
-
Lee, J.H.1
-
71
-
-
26444489716
-
A minor population of splenic dendritic cells expressing CD19 mediates IDO-dependent T cell suppression via type 1 interferon-signaling following B7 ligation
-
Baban, B., et al. 2005. A minor population of splenic dendritic cells expressing CD19 mediates IDO-dependent T cell suppression via type 1 interferon-signaling following B7 ligation. Int. Immunol. 17:909-919.
-
(2005)
Int. Immunol
, vol.17
, pp. 909-919
-
-
Baban, B.1
-
72
-
-
27144552597
-
Cutting edge: CpG oligonucleotides induce splenic CD19+ dendritic cells to acquire potent indoleamine 2,3-dioxygenase- dependent T cell regulatory functions via IFN type 1 signaling
-
Mellor, A.L., et al. 2005. Cutting edge: CpG oligonucleotides induce splenic CD19+ dendritic cells to acquire potent indoleamine 2,3-dioxygenase- dependent T cell regulatory functions via IFN type 1 signaling. J. Immunol. 175:5601-5605.
-
(2005)
J. Immunol
, vol.175
, pp. 5601-5605
-
-
Mellor, A.L.1
-
73
-
-
23844451052
-
Indoleamine 2,3-dioxygenase serves as a marker of poor prognosis in gene expression profiles of serous ovarian cancer cells
-
Okamoto, A., et al. 2005. Indoleamine 2,3-dioxygenase serves as a marker of poor prognosis in gene expression profiles of serous ovarian cancer cells. Clin. Cancer Res. 11:6030-6039.
-
(2005)
Clin. Cancer Res
, vol.11
, pp. 6030-6039
-
-
Okamoto, A.1
-
74
-
-
33845246900
-
Indoleamine 2,3-dioxygenase is a novel prognostic indicator for endometrial cancer
-
Ino, K., et al. 2006. Indoleamine 2,3-dioxygenase is a novel prognostic indicator for endometrial cancer. Br. J. Cancer. 95:1555-1561.
-
(2006)
Br. J. Cancer
, vol.95
, pp. 1555-1561
-
-
Ino, K.1
-
75
-
-
33644775726
-
Prognostic value of indoleamine 2,3-dioxygenase expression in colorectal cancer: Effect on tumor-infiltrating T cells
-
Brandacher, G., et al. 2006. Prognostic value of indoleamine 2,3-dioxygenase expression in colorectal cancer: effect on tumor-infiltrating T cells. Clin. Cancer Res. 12:1144-1151.
-
(2006)
Clin. Cancer Res
, vol.12
, pp. 1144-1151
-
-
Brandacher, G.1
-
76
-
-
33750321707
-
Interferons, immunity and cancer immunoediting
-
Dunn, G.P., Koebel, C.M., and Schreiber, R.D. 2006. Interferons, immunity and cancer immunoediting. Nat. Rev. Immunol. 6:836-848.
-
(2006)
Nat. Rev. Immunol
, vol.6
, pp. 836-848
-
-
Dunn, G.P.1
Koebel, C.M.2
Schreiber, R.D.3
-
77
-
-
21544432144
-
Accelerated chemically induced tumor development mediated by CD4+CD25+ regulatory T cells in wild-type hosts
-
Nishikawa, H., et al. 2005. Accelerated chemically induced tumor development mediated by CD4+CD25+ regulatory T cells in wild-type hosts. Proc. Natl. Acad. Sci. U. S. A. 102:9253-9257.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A
, vol.102
, pp. 9253-9257
-
-
Nishikawa, H.1
-
78
-
-
0035903324
-
Synergism of cytoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25+ regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoractive cytotoxic T lymphocyte responses
-
Sutmuller, R.P.M., et al. 2001. Synergism of cytoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25+ regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoractive cytotoxic T lymphocyte responses. J. Exp. Med. 194:823-832.
-
(2001)
J. Exp. Med
, vol.194
, pp. 823-832
-
-
Sutmuller, R.P.M.1
-
79
-
-
2442655250
-
Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance
-
Yang, Y., Huang, C.T., Huang, X., and Pardoll, D.M. 2004. Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance. Nat. Immunol. 5:508-515.
-
(2004)
Nat. Immunol
, vol.5
, pp. 508-515
-
-
Yang, Y.1
Huang, C.T.2
Huang, X.3
Pardoll, D.M.4
-
80
-
-
0346119234
-
Modulation of tryptophan catabolism by regulatory T cells
-
Fallarino, F., et al. 2003. Modulation of tryptophan catabolism by regulatory T cells. Nat. Immunol. 4:1206-1212.
-
(2003)
Nat. Immunol
, vol.4
, pp. 1206-1212
-
-
Fallarino, F.1
-
81
-
-
0036852242
-
When ligand becomes receptor-tolerance via B7 signaling on DCs
-
Finger, E.B., and Bluestone, J.A. 2002. When ligand becomes receptor-tolerance via B7 signaling on DCs. Nat. Immunol. 3:1056-1057.
-
(2002)
Nat. Immunol
, vol.3
, pp. 1056-1057
-
-
Finger, E.B.1
Bluestone, J.A.2
-
82
-
-
33845236614
-
CTLA-4 blockade decreases TGF-{beta}, indoleamine 2,3- dioxygenase, and viral RNA expression in tissues of SIV-mac251-infected macaques
-
Hryniewicz, A., et al. 2006. CTLA-4 blockade decreases TGF-{beta}, indoleamine 2,3- dioxygenase, and viral RNA expression in tissues of SIV-mac251-infected macaques. Blood. 108:3834-3842.
-
(2006)
Blood
, vol.108
, pp. 3834-3842
-
-
Hryniewicz, A.1
-
83
-
-
26844577145
-
Both regulatory T cells and antitumor effector T cells are primed in the same draining lymph nodes during tumor progression
-
Hiura, T., et al. 2005. Both regulatory T cells and antitumor effector T cells are primed in the same draining lymph nodes during tumor progression. J. Immunol. 175:5058-5066.
-
(2005)
J. Immunol
, vol.175
, pp. 5058-5066
-
-
Hiura, T.1
-
84
-
-
33646239606
-
Tumor-induced expansion of regulatory T cells by conversion of CD4+CD25- lymphocytes is thymus and proliferation independent
-
Valzasina, B., Piconese, S., Guiducci, C., and Colombo, M.P. 2006. Tumor-induced expansion of regulatory T cells by conversion of CD4+CD25- lymphocytes is thymus and proliferation independent. Cancer Res. 66:4488-4495.
-
(2006)
Cancer Res
, vol.66
, pp. 4488-4495
-
-
Valzasina, B.1
Piconese, S.2
Guiducci, C.3
Colombo, M.P.4
-
85
-
-
3142737258
-
Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells
-
Viguier, M., et al. 2004. Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells. J. Immunol. 173:1444-1453.
-
(2004)
J. Immunol
, vol.173
, pp. 1444-1453
-
-
Viguier, M.1
-
86
-
-
33947593164
-
Modulation of tryptophan catabolism by human leukemic cells results in the conversion of CD25- into CD25+ T regulatory cells
-
Curti, A., et al. 2007. Modulation of tryptophan catabolism by human leukemic cells results in the conversion of CD25- into CD25+ T regulatory cells. Blood. 109:2871-2877.
-
(2007)
Blood
, vol.109
, pp. 2871-2877
-
-
Curti, A.1
-
87
-
-
0042591416
-
Synergy between chemotherapy and immunotherapy in the treatment of established murine solid tumors
-
Nowak, A.K., Robinson, B.W., and Lake, R.A. 2003. Synergy between chemotherapy and immunotherapy in the treatment of established murine solid tumors. Cancer Res. 63:4490-4496.
-
(2003)
Cancer Res
, vol.63
, pp. 4490-4496
-
-
Nowak, A.K.1
Robinson, B.W.2
Lake, R.A.3
-
88
-
-
24744458859
-
Partial, but not complete, tumor-debulking surgery promotes protective antitumor memory when combined with chemotherapy and adjuvant immunotherapy
-
Broomfield, S., et al. 2005. Partial, but not complete, tumor-debulking surgery promotes protective antitumor memory when combined with chemotherapy and adjuvant immunotherapy. Cancer Res. 65:7580-7584.
-
(2005)
Cancer Res
, vol.65
, pp. 7580-7584
-
-
Broomfield, S.1
-
89
-
-
0036076114
-
T cell homeostatic proliferation elicits effective antitumor autoimmunity
-
doi:10.1172/JCI200215175
-
Dummer, W., et al. 2002. T cell homeostatic proliferation elicits effective antitumor autoimmunity. J. Clin. Invest. 110:185-192. doi:10.1172/JCI200215175.
-
(2002)
J. Clin. Invest
, vol.110
, pp. 185-192
-
-
Dummer, W.1
-
90
-
-
1942453326
-
Homeostatic expansion of T cells during immune insufficiency generates autoimmunity
-
King, C., Ilic, A., Koelsch, K., and Sarvetnick, N. 2004. Homeostatic expansion of T cells during immune insufficiency generates autoimmunity. Cell. 117:265-277.
-
(2004)
Cell
, vol.117
, pp. 265-277
-
-
King, C.1
Ilic, A.2
Koelsch, K.3
Sarvetnick, N.4
-
91
-
-
28544446699
-
Interleukin-7-dependent expansion and persistence of melanoma-specific T cells in lymphodepleted mice lead to tumor regression and editing
-
Wang, L.X., et al. 2005. Interleukin-7-dependent expansion and persistence of melanoma-specific T cells in lymphodepleted mice lead to tumor regression and editing. Cancer Res. 65:10569-10577.
-
(2005)
Cancer Res
, vol.65
, pp. 10569-10577
-
-
Wang, L.X.1
-
92
-
-
33749135271
-
Homeostatic proliferation as an isolated variable reverses CD8+ T Cell anergy and promotes tumor rejection
-
Brown, I.E., Blank, C., Kline, J., Kacha, A.K., and Gajewski, T.F. 2006. Homeostatic proliferation as an isolated variable reverses CD8+ T Cell anergy and promotes tumor rejection. J. Immunol. 177:4521-4529.
-
(2006)
J. Immunol
, vol.177
, pp. 4521-4529
-
-
Brown, I.E.1
Blank, C.2
Kline, J.3
Kacha, A.K.4
Gajewski, T.F.5
-
93
-
-
0023682494
-
Cyclophosphamide (Cy)-facilitated adoptive immunotherapy of a Cy-resistant tumour. Evidence that Cy permits the expression of adoptive T-cell mediated immunity by removing suppressor T cells rather than by reducing tumour burden
-
Awwad, M., and North, R.J. 1988. Cyclophosphamide (Cy)-facilitated adoptive immunotherapy of a Cy-resistant tumour. Evidence that Cy permits the expression of adoptive T-cell mediated immunity by removing suppressor T cells rather than by reducing tumour burden. Immunology. 65:87-92.
-
(1988)
Immunology
, vol.65
, pp. 87-92
-
-
Awwad, M.1
North, R.J.2
-
94
-
-
1642378018
-
CD4+CD25+ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative
-
Ghiringhelli, F., et al. 2004. CD4+CD25+ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative. Eur. J. Immunol. 34:336-344.
-
(2004)
Eur. J. Immunol
, vol.34
, pp. 336-344
-
-
Ghiringhelli, F.1
-
95
-
-
15944410592
-
Inhibition of CD4+25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide
-
Lutsiak, M.E., et al. 2005. Inhibition of CD4+25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide. Blood. 105:2862-2868.
-
(2005)
Blood
, vol.105
, pp. 2862-2868
-
-
Lutsiak, M.E.1
-
96
-
-
24744432528
-
Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine
-
Beyer, M., et al. 2005. Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine. Blood. 106:2018-2025.
-
(2005)
Blood
, vol.106
, pp. 2018-2025
-
-
Beyer, M.1
-
97
-
-
0035328683
-
Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macrophagecolony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice
-
Machiels, J.P., et al. 2001. Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macrophagecolony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice. Cancer Res. 61:3689-3697.
-
(2001)
Cancer Res
, vol.61
, pp. 3689-3697
-
-
Machiels, J.P.1
-
98
-
-
0042024964
-
CpG oligodeoxynucleotides potentiate the antitumor effects of chemotherapy or tumor resection in an orthotopic murine model of rhabdomyosarcoma
-
Weigel, B.J., Rodeberg, D.A., Krieg, A.M., and Blazar, B.R. 2003. CpG oligodeoxynucleotides potentiate the antitumor effects of chemotherapy or tumor resection in an orthotopic murine model of rhabdomyosarcoma. Clin. Cancer Res. 9:3105-3114.
-
(2003)
Clin. Cancer Res
, vol.9
, pp. 3105-3114
-
-
Weigel, B.J.1
Rodeberg, D.A.2
Krieg, A.M.3
Blazar, B.R.4
-
99
-
-
25844484607
-
Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells
-
Gattinoni, L., et al. 2005. Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells. J. Exp. Med. 202:907-912.
-
(2005)
J. Exp. Med
, vol.202
, pp. 907-912
-
-
Gattinoni, L.1
-
100
-
-
33644531900
-
Chemoimmunotherapy of tumors: Cyclophosphamide synergizes with exosome based vaccines
-
Taieb, J., et al. 2006. Chemoimmunotherapy of tumors: cyclophosphamide synergizes with exosome based vaccines. J. Immunol. 176:2722-2729.
-
(2006)
J. Immunol
, vol.176
, pp. 2722-2729
-
-
Taieb, J.1
-
101
-
-
0037174674
-
Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes
-
Dudley, M.E., et al. 2002. Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes. Science. 298:850-854.
-
(2002)
Science
, vol.298
, pp. 850-854
-
-
Dudley, M.E.1
-
102
-
-
33749624177
-
Cancer regression in patients after transfer of genetically engineered lymphocytes
-
Morgan, R.A., et al. 2006. Cancer regression in patients after transfer of genetically engineered lymphocytes. Science. 314:126-129.
-
(2006)
Science
, vol.314
, pp. 126-129
-
-
Morgan, R.A.1
-
103
-
-
33846689594
-
Inhibition of IDO in dendritic cells by stereoisomers of 1-methyl-tryptophan correlates with anti-tumor responses
-
Hou, D.Y., et al. 2007. Inhibition of IDO in dendritic cells by stereoisomers of 1-methyl-tryptophan correlates with anti-tumor responses. Cancer Res. 67:792-801.
-
(2007)
Cancer Res
, vol.67
, pp. 792-801
-
-
Hou, D.Y.1
-
104
-
-
4243193742
-
Evolution of somatic mutations in mammary tumors in transgenic mice is influenced by the inherited genotype
-
Podsypanina, K., Li, Y., and Varmus, H.E. 2004. Evolution of somatic mutations in mammary tumors in transgenic mice is influenced by the inherited genotype. BMC Med. 2:24-34.
-
(2004)
BMC Med
, vol.2
, pp. 24-34
-
-
Podsypanina, K.1
Li, Y.2
Varmus, H.E.3
-
105
-
-
0001044539
-
Evaluation of functionalized tryptophan derivatives and related compounds as competitive inhibitors of indoleamine 2,3-dioxygenase
-
Peterson, A.C., et al. 1994. Evaluation of functionalized tryptophan derivatives and related compounds as competitive inhibitors of indoleamine 2,3-dioxygenase. Med. Chem. Res. 3:531-544.
-
(1994)
Med. Chem. Res
, vol.3
, pp. 531-544
-
-
Peterson, A.C.1
-
106
-
-
33745616804
-
Hepatocyte growth factor favors monocyte differentiation into regulatory interleukin (IL)-10++IL-12low/neg accessory cells with dendritic-cell features
-
Rutella, S., et al. 2006. Hepatocyte growth factor favors monocyte differentiation into regulatory interleukin (IL)-10++IL-12low/neg accessory cells with dendritic-cell features. Blood. 108:218-227.
-
(2006)
Blood
, vol.108
, pp. 218-227
-
-
Rutella, S.1
-
107
-
-
33751574468
-
Synovial autoreactive T cells in rheumatoid arthritis resist IDO-mediated inhibition
-
Zhu, L., et al. 2006. Synovial autoreactive T cells in rheumatoid arthritis resist IDO-mediated inhibition. J. Immunol. 177:8226-8233.
-
(2006)
J. Immunol
, vol.177
, pp. 8226-8233
-
-
Zhu, L.1
-
108
-
-
33746912362
-
1-methyl-tryptophan can interfere with TLR signaling in dendritic cells independently of IDO activity
-
Agaugue, S., Perrin-Cocon, L., Coutant, F., Andre, P., and Lotteau, V. 2006. 1-methyl-tryptophan can interfere with TLR signaling in dendritic cells independently of IDO activity. J. Immunol. 177:2061-2071.
-
(2006)
J. Immunol
, vol.177
, pp. 2061-2071
-
-
Agaugue, S.1
Perrin-Cocon, L.2
Coutant, F.3
Andre, P.4
Lotteau, V.5
-
109
-
-
0034832968
-
Enhancement of innate immunity against Mycobacterium avium infection by immunostimulatory DNA is mediated by indoleamine 2,3-dioxygenase
-
Hayashi, T., et al. 2001. Enhancement of innate immunity against Mycobacterium avium infection by immunostimulatory DNA is mediated by indoleamine 2,3-dioxygenase. Infect. Immun. 69:6156-6164.
-
(2001)
Infect. Immun
, vol.69
, pp. 6156-6164
-
-
Hayashi, T.1
-
110
-
-
0036244045
-
Proteomic analysis of cytokine induced proteins in human intestinal epithelial cells: Implications for inflammatory bowel diseases
-
Barcelo-Batllori, S., et al. 2002. Proteomic analysis of cytokine induced proteins in human intestinal epithelial cells: implications for inflammatory bowel diseases. Proteomics. 2:551-560.
-
(2002)
Proteomics
, vol.2
, pp. 551-560
-
-
Barcelo-Batllori, S.1
-
111
-
-
8444253637
-
Cutting edge: Human eosinophils regulate T cell subset selection through indoleamine 2,3-dioxygenase
-
Odemuyiwa, S.O., et al. 2004. Cutting edge: human eosinophils regulate T cell subset selection through indoleamine 2,3-dioxygenase. J. Immunol. 173:5909-5913.
-
(2004)
J. Immunol
, vol.173
, pp. 5909-5913
-
-
Odemuyiwa, S.O.1
-
112
-
-
33745819629
-
Expression of indoleamine 2,3-dioxygenase (IDO) by endothelial cells: Implications for the control of alloresponses
-
Beutelspacher, S.C., et al. 2006. Expression of indoleamine 2,3-dioxygenase (IDO) by endothelial cells: implications for the control of alloresponses. Am. J. Transplant. 6:1320-1330.
-
(2006)
Am. J. Transplant
, vol.6
, pp. 1320-1330
-
-
Beutelspacher, S.C.1
-
113
-
-
0019748201
-
Specific induction of indoleamine 2,3-dioxygenase by bacterial lipopolysaccharide in the mouse lung
-
Yoshida, R., Urade, Y., Nakata, K., Watanabe, Y., and Hayashi, O. 1981. Specific induction of indoleamine 2,3-dioxygenase by bacterial lipopolysaccharide in the mouse lung. Arch. Biochem. Biophys. 212:629-637.
-
(1981)
Arch. Biochem. Biophys
, vol.212
, pp. 629-637
-
-
Yoshida, R.1
Urade, Y.2
Nakata, K.3
Watanabe, Y.4
Hayashi, O.5
-
114
-
-
30944460918
-
Systemic application of CpG-rich DNA suppresses adaptive T cell immunity via induction of IDO
-
Wingender, G., et al. 2006. Systemic application of CpG-rich DNA suppresses adaptive T cell immunity via induction of IDO. Eur. J. Immunol. 36:12-20.
-
(2006)
Eur. J. Immunol
, vol.36
, pp. 12-20
-
-
Wingender, G.1
-
115
-
-
1842631153
-
Immunotherapeutic uses of CpG oligodeoxynucleotides
-
Klinman, D.M. 2004. Immunotherapeutic uses of CpG oligodeoxynucleotides. Nat. Rev. Immunol. 4:249-258.
-
(2004)
Nat. Rev. Immunol
, vol.4
, pp. 249-258
-
-
Klinman, D.M.1
-
116
-
-
14644390867
-
Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909
-
doi:10.1172/JCI200523373
-
Speiser, D.E., et al. 2005. Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909. J. Clin. Invest. 115:739-746. doi:10.1172/JCI200523373.
-
(2005)
J. Clin. Invest
, vol.115
, pp. 739-746
-
-
Speiser, D.E.1
-
117
-
-
34248148289
-
CPG 7909, a TLR9 agonist, added to first line taxane/platinum for advanced non-small cell lung cancer, a randomized, controlled phase II study
-
Leichman, G., et al. 2005. CPG 7909, a TLR9 agonist, added to first line taxane/platinum for advanced non-small cell lung cancer, a randomized, controlled phase II study. J. Clin. Oncol. 23(Suppl.):7039.
-
(2005)
J. Clin. Oncol
, vol.23
, Issue.SUPPL.
, pp. 7039
-
-
Leichman, G.1
-
118
-
-
5044220930
-
IDO expression by dendritic cells: Tolerance and tryptophan catabolism
-
Mellor, A., and Munn, D.H. 2004. IDO expression by dendritic cells: tolerance and tryptophan catabolism. Nat. Rev. Immunol. 4:762-774.
-
(2004)
Nat. Rev. Immunol
, vol.4
, pp. 762-774
-
-
Mellor, A.1
Munn, D.H.2
-
119
-
-
0037018097
-
Adjuvants of immunity: Harnessing innate immunity to promote adaptive immunity
-
Bendelac, A., and Medzhitov, R. 2002. Adjuvants of immunity: harnessing innate immunity to promote adaptive immunity. J. Exp. Med. 195:F19-F23.
-
(2002)
J. Exp. Med
, vol.195
-
-
Bendelac, A.1
Medzhitov, R.2
-
120
-
-
22544484459
-
Bacille Calmette-Guerin inoculation induces chronic activation of peripheral and brain indoleamine 2,3-dioxygenase in mice
-
Moreau, M., et al. 2005. Bacille Calmette-Guerin inoculation induces chronic activation of peripheral and brain indoleamine 2,3-dioxygenase in mice. J. Infect. Dis. 192:537-544.
-
(2005)
J. Infect. Dis
, vol.192
, pp. 537-544
-
-
Moreau, M.1
-
121
-
-
33845304287
-
Indoleamine 2,3-dioxygenase-expressing dendritic cells form suppurative granulomas following Listeria monocytogenes infection
-
doi:10.1172/JCI28996
-
Popov, A., et al. 2006. Indoleamine 2,3-dioxygenase-expressing dendritic cells form suppurative granulomas following Listeria monocytogenes infection. J. Clin. Invest. 116:3160-3170. doi:10.1172/JCI28996.
-
(2006)
J. Clin. Invest
, vol.116
, pp. 3160-3170
-
-
Popov, A.1
-
122
-
-
23244437934
-
The therapeutic potential of 4-1BB (CD137) in cancer
-
Nam, K.O., Kang, W.J., Kwon, B.S., Kim, S.J., and Lee, H.W. 2005. The therapeutic potential of 4-1BB (CD137) in cancer. Curr. Cancer Drug Targets. 5:357-363.
-
(2005)
Curr. Cancer Drug Targets
, vol.5
, pp. 357-363
-
-
Nam, K.O.1
Kang, W.J.2
Kwon, B.S.3
Kim, S.J.4
Lee, H.W.5
-
123
-
-
33747119866
-
4-1BB-mediated amelioration of experimental autoimmune uveoretinitis is caused by indoleamine 2,3-dioxygenase-dependent mechanisms
-
Choi, B.K., Asai, T., Vinay, D.S., Kim, Y.H., and Kwon, B.S. 2006. 4-1BB-mediated amelioration of experimental autoimmune uveoretinitis is caused by indoleamine 2,3-dioxygenase-dependent mechanisms. Cytokine. 34:233-242.
-
(2006)
Cytokine
, vol.34
, pp. 233-242
-
-
Choi, B.K.1
Asai, T.2
Vinay, D.S.3
Kim, Y.H.4
Kwon, B.S.5
-
124
-
-
7044261952
-
4-1BB-mediated immunotherapy of rheumatoid arthritis
-
Seo, S.K., et al. 2004. 4-1BB-mediated immunotherapy of rheumatoid arthritis. Nat. Med. 10:1088-1094.
-
(2004)
Nat. Med
, vol.10
, pp. 1088-1094
-
-
Seo, S.K.1
-
125
-
-
30044437872
-
Breaking down the barriers to cancer immunotherapy
-
Pure, E., Allison, J.P., and Schreiber, R.D. 2005. Breaking down the barriers to cancer immunotherapy. Nat. Immunol. 6:1207-1210.
-
(2005)
Nat. Immunol
, vol.6
, pp. 1207-1210
-
-
Pure, E.1
Allison, J.P.2
Schreiber, R.D.3
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