-
1
-
-
44449091598
-
Colon cancer: update on adjuvant therapy
-
Mano M.S., and Duhoux F. Colon cancer: update on adjuvant therapy. Clin. Colorectal Cancer 7 (2008) 178-183
-
(2008)
Clin. Colorectal Cancer
, vol.7
, pp. 178-183
-
-
Mano, M.S.1
Duhoux, F.2
-
2
-
-
0019401759
-
Treatment of primary breast cancer with chemotherapy and tamoxifen
-
Fisher B., et al. Treatment of primary breast cancer with chemotherapy and tamoxifen. N. Engl. J. Med. 305 (1981) 1-6
-
(1981)
N. Engl. J. Med.
, vol.305
, pp. 1-6
-
-
Fisher, B.1
-
3
-
-
26844536978
-
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
-
Romond E.H., et al. Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N. Engl. J. Med. 353 (2005) 1673-1684
-
(2005)
N. Engl. J. Med.
, vol.353
, pp. 1673-1684
-
-
Romond, E.H.1
-
4
-
-
85013312416
-
Tumor angiogenesis: therapeutic implications
-
Folkman J. Tumor angiogenesis: therapeutic implications. N. Engl. J. Med. 285 (1971) 1182-1186
-
(1971)
N. Engl. J. Med.
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
5
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H., et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N. Engl. J. Med. 350 (2004) 2335-2342
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
-
6
-
-
34248173883
-
Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200
-
Giantonio B.J., et al. Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. J. Clin. Oncol. 25 (2007) 1539-1544
-
(2007)
J. Clin. Oncol.
, vol.25
, pp. 1539-1544
-
-
Giantonio, B.J.1
-
7
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
-
Sandler A., et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N. Engl. J. Med. 355 (2006) 2542-2550
-
(2006)
N. Engl. J. Med.
, vol.355
, pp. 2542-2550
-
-
Sandler, A.1
-
8
-
-
37549040613
-
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
-
Miller K., et al. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N. Engl. J. Med. 357 (2007) 2666-2676
-
(2007)
N. Engl. J. Med.
, vol.357
, pp. 2666-2676
-
-
Miller, K.1
-
9
-
-
70350461699
-
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
-
Friedman H.S., et al. Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma. J. Clin. Oncol. 27 (2009) 4733-4740
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 4733-4740
-
-
Friedman, H.S.1
-
10
-
-
59949083263
-
Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma
-
Kreisl T.N., et al. Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma. J. Clin. Oncol. 27 (2009) 740-745
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 740-745
-
-
Kreisl, T.N.1
-
11
-
-
67649298020
-
Bevacizumab: current indications and future development for management of solid tumors
-
Jenab-Wolcott J., and Giantonio B.J. Bevacizumab: current indications and future development for management of solid tumors. Expert Opin. Biol. Ther. 9 (2009) 507-517
-
(2009)
Expert Opin. Biol. Ther.
, vol.9
, pp. 507-517
-
-
Jenab-Wolcott, J.1
Giantonio, B.J.2
-
12
-
-
33845961014
-
Bevacizumab: an angiogenesis inhibitor for the treatment of solid malignancies
-
Shih T., and Lindley C. Bevacizumab: an angiogenesis inhibitor for the treatment of solid malignancies. Clin. Ther. 28 (2006) 1779-1802
-
(2006)
Clin. Ther.
, vol.28
, pp. 1779-1802
-
-
Shih, T.1
Lindley, C.2
-
13
-
-
63449090307
-
Neuropilins in tumor biology
-
Bagri A., et al. Neuropilins in tumor biology. Clin. Cancer Res. 15 (2009) 1860-1864
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 1860-1864
-
-
Bagri, A.1
-
14
-
-
14644440555
-
Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis
-
Hicklin D.J., and Ellis L. Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. J. Clin. Oncol. 23 (2005) 1011-1027
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 1011-1027
-
-
Hicklin, D.J.1
Ellis, L.2
-
15
-
-
33947191055
-
Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma
-
Vredenburgh J.J., et al. Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma. Clin. Cancer Res. 13 (2007) 1253-1259
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 1253-1259
-
-
Vredenburgh, J.J.1
-
16
-
-
33748475636
-
The use of bevacizumab to palliate symptomatic ascites in patients with refractory ovarian carcinoma
-
Numnum T.M., et al. The use of bevacizumab to palliate symptomatic ascites in patients with refractory ovarian carcinoma. Gynecol. Oncol. 102 (2006) 425-428
-
(2006)
Gynecol. Oncol.
, vol.102
, pp. 425-428
-
-
Numnum, T.M.1
-
17
-
-
33644824747
-
Improving long-term outcomes for patients with liver metastases from colorectal cancer
-
Chong G., and Cunningham D. Improving long-term outcomes for patients with liver metastases from colorectal cancer. J. Clin. Oncol. 23 (2005) 9063-9066
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 9063-9066
-
-
Chong, G.1
Cunningham, D.2
-
18
-
-
24644454338
-
Surgical resection after downsizing of colorectal liver metastasis in the era of bevacizumab
-
Ellis L.M., et al. Surgical resection after downsizing of colorectal liver metastasis in the era of bevacizumab. J. Clin. Oncol. 23 (2005) 4853-4855
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 4853-4855
-
-
Ellis, L.M.1
-
19
-
-
70350721785
-
Quantifying antivascular effects of monoclonal antibodies to vascular endothelial growth factor
-
O'Connor J., et al. Quantifying antivascular effects of monoclonal antibodies to vascular endothelial growth factor. Clin. Cancer Res. 15 (2009) 6674-6682
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 6674-6682
-
-
O'Connor, J.1
-
20
-
-
11844254414
-
Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy
-
Jain R. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 307 (2005) 58-62
-
(2005)
Science
, vol.307
, pp. 58-62
-
-
Jain, R.1
-
21
-
-
33744466541
-
Antiangiogenic therapy: a universal chemosensitization strategy for cancer?
-
Kerbel R. Antiangiogenic therapy: a universal chemosensitization strategy for cancer?. Science 312 (2006) 1171-1175
-
(2006)
Science
, vol.312
, pp. 1171-1175
-
-
Kerbel, R.1
-
22
-
-
0030018743
-
A systems approach to cancer therapy. (Antioncogenics + standard cytotoxics→mechanism(s) of interaction)
-
Teicher B.A. A systems approach to cancer therapy. (Antioncogenics + standard cytotoxics→mechanism(s) of interaction). Cancer Metastasis Rev. 15 (1996) 247-272
-
(1996)
Cancer Metastasis Rev.
, vol.15
, pp. 247-272
-
-
Teicher, B.A.1
-
23
-
-
0029787909
-
Tumor angiogenesis and interstitial hypertension
-
Boucher Y., et al. Tumor angiogenesis and interstitial hypertension. Cancer Res. 56 (1996) 4264-4266
-
(1996)
Cancer Res.
, vol.56
, pp. 4264-4266
-
-
Boucher, Y.1
-
24
-
-
32944478893
-
Effect of inhibition of vascular endothelial growth factor signaling on distribution of extravasated antibodies in tumors
-
Nakahara T., et al. Effect of inhibition of vascular endothelial growth factor signaling on distribution of extravasated antibodies in tumors. Cancer Res. 66 (2006) 1434-1445
-
(2006)
Cancer Res.
, vol.66
, pp. 1434-1445
-
-
Nakahara, T.1
-
25
-
-
2542628099
-
Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors
-
Tong R.T., et al. Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors. Cancer Res. 64 (2004) 3731-3736
-
(2004)
Cancer Res.
, vol.64
, pp. 3731-3736
-
-
Tong, R.T.1
-
26
-
-
0029949160
-
Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody
-
Yuan F., et al. Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 14765-14770
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 14765-14770
-
-
Yuan, F.1
-
27
-
-
0029150245
-
Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size
-
Yuan F., et al. Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size. Cancer Res. 55 (1995) 3752-3756
-
(1995)
Cancer Res.
, vol.55
, pp. 3752-3756
-
-
Yuan, F.1
-
28
-
-
17144417329
-
Resistance of tumor interstitial pressure to the penetration of intraperitoneally delivered antibodies into metastatic ovarian tumors
-
Flessner M.F., et al. Resistance of tumor interstitial pressure to the penetration of intraperitoneally delivered antibodies into metastatic ovarian tumors. Clin. Cancer Res. 11 (2005) 3117-3125
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 3117-3125
-
-
Flessner, M.F.1
-
29
-
-
0037182861
-
VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism
-
Gerber H.-P., et al. VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism. Nature 417 (2002) 954-958
-
(2002)
Nature
, vol.417
, pp. 954-958
-
-
Gerber, H.-P.1
-
30
-
-
33748051406
-
Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor
-
Bao S., et al. Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor. Cancer Res. 66 (2006) 7843-7848
-
(2006)
Cancer Res.
, vol.66
, pp. 7843-7848
-
-
Bao, S.1
-
31
-
-
72449150594
-
-
Jiang, H. et al. (2010) Low-dose metronomic paclitaxel chemotherapy suppresses breast tumors and metastases in mice. Pathways mediating VEGF-independent tumor angiogenesis. Cancer Invest., doi:10.3109/07357900902744510
-
Jiang, H. et al. (2010) Low-dose metronomic paclitaxel chemotherapy suppresses breast tumors and metastases in mice. Pathways mediating VEGF-independent tumor angiogenesis. Cancer Invest., doi:10.3109/07357900902744510
-
-
-
-
32
-
-
5444225991
-
Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis
-
Yang L., et al. Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis. Cancer Cell 6 (2004) 409-421
-
(2004)
Cancer Cell
, vol.6
, pp. 409-421
-
-
Yang, L.1
-
33
-
-
33749005405
-
Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors
-
Shaked Y., et al. Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors. Science 313 (2006) 1785-1787
-
(2006)
Science
, vol.313
, pp. 1785-1787
-
-
Shaked, Y.1
-
34
-
-
68849115626
-
Micrometastases or isolated tumor cells and the outcome of breast cancer
-
de Boer M., et al. Micrometastases or isolated tumor cells and the outcome of breast cancer. N. Engl. J. Med. 361 (2009) 653-663
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 653-663
-
-
de Boer, M.1
-
35
-
-
41349099104
-
Cancer statistics, 2008
-
Jemal A., et al. Cancer statistics, 2008. CA Cancer J. Clin. 58 (2008) 71-96
-
(2008)
CA Cancer J. Clin.
, vol.58
, pp. 71-96
-
-
Jemal, A.1
-
36
-
-
0037967272
-
Tumorigenesis and the angiogenic switch
-
Bergers G., and Benjamin L. Tumorigenesis and the angiogenic switch. Nat. Rev. Cancer 3 (2003) 401-410
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 401-410
-
-
Bergers, G.1
Benjamin, L.2
-
37
-
-
33645226260
-
Interruption of tumor dormancy by a transient angiogenic burst within the tumor microenvironment
-
Indraccolo S., et al. Interruption of tumor dormancy by a transient angiogenic burst within the tumor microenvironment. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 4216-4221
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 4216-4221
-
-
Indraccolo, S.1
-
38
-
-
59149083473
-
Transcriptional switch of dormant tumors to fast-growing angiogenic phenotype
-
Almog N., et al. Transcriptional switch of dormant tumors to fast-growing angiogenic phenotype. Cancer Res. 69 (2009) 836-844
-
(2009)
Cancer Res.
, vol.69
, pp. 836-844
-
-
Almog, N.1
-
39
-
-
33644763050
-
A model of human tumor dormancy: an angiogenic switch from the nonangiogenic phenotype
-
Naumov G.N., et al. A model of human tumor dormancy: an angiogenic switch from the nonangiogenic phenotype. J. Natl. Cancer Inst. 98 (2006) 316-325
-
(2006)
J. Natl. Cancer Inst.
, vol.98
, pp. 316-325
-
-
Naumov, G.N.1
-
40
-
-
59449084872
-
Maintenance treatment with bevacizumab prolongs survival in an in vivo ovarian cancer model
-
Mabuchi S., et al. Maintenance treatment with bevacizumab prolongs survival in an in vivo ovarian cancer model. Clin. Cancer Res. 14 (2008) 7781-7789
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 7781-7789
-
-
Mabuchi, S.1
-
41
-
-
58149521889
-
In vivo activity of novel capecitabine regimens alone and with bevacizumab and oxaliplatin in colorectal cancer xenograft models
-
Kolinsky K., et al. In vivo activity of novel capecitabine regimens alone and with bevacizumab and oxaliplatin in colorectal cancer xenograft models. Mol. Cancer Ther. 8 (2009) 75-82
-
(2009)
Mol. Cancer Ther.
, vol.8
, pp. 75-82
-
-
Kolinsky, K.1
-
42
-
-
57349110570
-
Combining bevacizumab with temozolomide increases the antitumor efficacy of temozolomide in a human glioblastoma orthotopic xenograft model
-
Mathieu, V. et al. (2008) Combining bevacizumab with temozolomide increases the antitumor efficacy of temozolomide in a human glioblastoma orthotopic xenograft model. Neoplasia 10, 1383-1392
-
(2008)
Neoplasia
, vol.10
, pp. 1383-1392
-
-
Mathieu, V.1
-
43
-
-
0031038068
-
Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis
-
Relf M., et al. Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis. Cancer Res. 57 (1997) 963-969
-
(1997)
Cancer Res.
, vol.57
, pp. 963-969
-
-
Relf, M.1
-
44
-
-
26644471951
-
Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors
-
Casanovas O., et al. Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors. Cancer Cell 8 (2005) 299-309
-
(2005)
Cancer Cell
, vol.8
, pp. 299-309
-
-
Casanovas, O.1
-
45
-
-
0033580889
-
Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF
-
Holash J., et al. Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF. Science 284 (1999) 1994-1998
-
(1999)
Science
, vol.284
, pp. 1994-1998
-
-
Holash, J.1
-
46
-
-
39849102836
-
HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion
-
Du R., et al. HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion. Cancer Cell 13 (2008) 206-220
-
(2008)
Cancer Cell
, vol.13
, pp. 206-220
-
-
Du, R.1
-
47
-
-
63049090100
-
Metastasis: from dissemination to organ-specific colonization
-
Nguyen D., et al. Metastasis: from dissemination to organ-specific colonization. Nat. Rev. Cancer 9 (2009) 274-284
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 274-284
-
-
Nguyen, D.1
-
48
-
-
11844268150
-
Access of tumor-derived macromolecules and cells to the blood: an electron microscopical study of structural barriers in microvessel clusters in highly malignant primary prostate carcinomas
-
Wieser E., et al. Access of tumor-derived macromolecules and cells to the blood: an electron microscopical study of structural barriers in microvessel clusters in highly malignant primary prostate carcinomas. Prostate 62 (2005) 123-132
-
(2005)
Prostate
, vol.62
, pp. 123-132
-
-
Wieser, E.1
-
49
-
-
3042548695
-
Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts
-
Inai T., et al. Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts. Am. J. Pathol. 165 (2004) 35-52
-
(2004)
Am. J. Pathol.
, vol.165
, pp. 35-52
-
-
Inai, T.1
-
50
-
-
33846149645
-
AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients
-
Batchelor T.T., et al. AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. Cancer Cell 11 (2007) 83-95
-
(2007)
Cancer Cell
, vol.11
, pp. 83-95
-
-
Batchelor, T.T.1
-
51
-
-
34047260282
-
Effect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: insights from a mathematical model
-
Jain R., et al. Effect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: insights from a mathematical model. Cancer Res. 67 (2007) 2729-2735
-
(2007)
Cancer Res.
, vol.67
, pp. 2729-2735
-
-
Jain, R.1
-
52
-
-
33644643376
-
Pericytes limit tumor cell metastasis
-
Xian X., et al. Pericytes limit tumor cell metastasis. J. Clin. Invest. 116 (2006) 642-651
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 642-651
-
-
Xian, X.1
-
53
-
-
0038481970
-
The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited
-
Fidler I.J. The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nat. Rev. Cancer 3 (2003) 453-458
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 453-458
-
-
Fidler, I.J.1
-
54
-
-
33845890001
-
The vascular niche and its basement membrane
-
Nikolova G., et al. The vascular niche and its basement membrane. Trends Cell Biol. 17 (2007) 19-25
-
(2007)
Trends Cell Biol.
, vol.17
, pp. 19-25
-
-
Nikolova, G.1
-
55
-
-
33751504690
-
Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis
-
Hiratsuka S., et al. Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis. Nat. Cell Biol. 8 (2006) 1369-1375
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 1369-1375
-
-
Hiratsuka, S.1
-
56
-
-
63049121364
-
The metastatic niche: adapting the foreign soil
-
Psaila B., and Lyden D. The metastatic niche: adapting the foreign soil. Nat. Rev. Cancer 9 (2009) 285-293
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 285-293
-
-
Psaila, B.1
Lyden, D.2
-
57
-
-
28644432204
-
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
-
Kaplan R., et al. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 438 (2005) 820-827
-
(2005)
Nature
, vol.438
, pp. 820-827
-
-
Kaplan, R.1
-
58
-
-
60649087564
-
Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis
-
Ebos J.M., et al. Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. Cancer Cell 15 (2009) 232-239
-
(2009)
Cancer Cell
, vol.15
, pp. 232-239
-
-
Ebos, J.M.1
-
59
-
-
38149006909
-
Endothelial progenitor cells control the angiogenic switch in mouse lung metastasis
-
Gao D., et al. Endothelial progenitor cells control the angiogenic switch in mouse lung metastasis. Science 319 (2008) 195-198
-
(2008)
Science
, vol.319
, pp. 195-198
-
-
Gao, D.1
-
60
-
-
70349280375
-
VEGFR1-activity-independent metastasis formation
-
discussion E5
-
Dawson M.R., et al. VEGFR1-activity-independent metastasis formation. Nature 461 (2009) E4 discussion E5
-
(2009)
Nature
, vol.461
-
-
Dawson, M.R.1
-
61
-
-
73849129203
-
-
Kienast, Y. et al. (2010) Real-time imaging reveals the single steps of brain metastasis formation. Nat. Med. 16, 116-122
-
Kienast, Y. et al. (2010) Real-time imaging reveals the single steps of brain metastasis formation. Nat. Med. 16, 116-122
-
-
-
-
62
-
-
0035999133
-
Critical determinants of metastasis
-
Fidler I.J. Critical determinants of metastasis. Semin. Cancer Biol. 12 (2002) 89-96
-
(2002)
Semin. Cancer Biol.
, vol.12
, pp. 89-96
-
-
Fidler, I.J.1
-
63
-
-
52949139787
-
Seeding and propagation of untransformed mouse mammary cells in the lung
-
Podsypanina K., et al. Seeding and propagation of untransformed mouse mammary cells in the lung. Science 321 (2008) 1841-1844
-
(2008)
Science
, vol.321
, pp. 1841-1844
-
-
Podsypanina, K.1
-
64
-
-
0021186338
-
Metastatic behavior of human tumor cell lines grown in the nude mouse
-
Kozlowski J.M., et al. Metastatic behavior of human tumor cell lines grown in the nude mouse. Cancer Res. 44 (1984) 3522-3529
-
(1984)
Cancer Res.
, vol.44
, pp. 3522-3529
-
-
Kozlowski, J.M.1
-
65
-
-
0028935608
-
Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis
-
Warren R.S., et al. Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis. J. Clin. Invest. 95 (1995) 1789-1797
-
(1995)
J. Clin. Invest.
, vol.95
, pp. 1789-1797
-
-
Warren, R.S.1
-
66
-
-
0017748871
-
Surgical adjuvant chemotherapy of metastatic murine tumors
-
Schabel F.M. Surgical adjuvant chemotherapy of metastatic murine tumors. Cancer 40 (1977) 558-568
-
(1977)
Cancer
, vol.40
, pp. 558-568
-
-
Schabel, F.M.1
-
67
-
-
0034787967
-
MMP-9 secretion and MMP-2 activation distinguish invasive and metastatic sublines of a mouse mammary carcinoma system showing epithelial-mesenchymal transition traits
-
Tester A.M., et al. MMP-9 secretion and MMP-2 activation distinguish invasive and metastatic sublines of a mouse mammary carcinoma system showing epithelial-mesenchymal transition traits. Clin. Exp. Metastasis 18 (2000) 553-560
-
(2000)
Clin. Exp. Metastasis
, vol.18
, pp. 553-560
-
-
Tester, A.M.1
-
68
-
-
0021676032
-
Different metastatic modes of malignant melanoma implanted in the ear of young and old mice
-
Hirayama R., et al. Different metastatic modes of malignant melanoma implanted in the ear of young and old mice. Cancer Immunol. Immunother. 18 (1984) 209-214
-
(1984)
Cancer Immunol. Immunother.
, vol.18
, pp. 209-214
-
-
Hirayama, R.1
-
69
-
-
33748075460
-
Imaging steps of lymphatic metastasis reveals that vascular endothelial growth factor-C increases metastasis by increasing delivery of cancer cells to lymph nodes: therapeutic implications
-
Hoshida T., et al. Imaging steps of lymphatic metastasis reveals that vascular endothelial growth factor-C increases metastasis by increasing delivery of cancer cells to lymph nodes: therapeutic implications. Cancer Res. 66 (2006) 8065-8075
-
(2006)
Cancer Res.
, vol.66
, pp. 8065-8075
-
-
Hoshida, T.1
-
70
-
-
0024368793
-
Development of an animal model to study the biology of recurrent colorectal cancer originating from mesenteric lymph system metastases
-
Schackert H.K., and Fidler I.J. Development of an animal model to study the biology of recurrent colorectal cancer originating from mesenteric lymph system metastases. Int. J. Cancer 44 (1989) 177-181
-
(1989)
Int. J. Cancer
, vol.44
, pp. 177-181
-
-
Schackert, H.K.1
Fidler, I.J.2
-
71
-
-
0029818147
-
Progressive upregulation of metastasis-related genes in human colon cancer cells implanted into the cecum of nude mice
-
Takahashi Y., et al. Progressive upregulation of metastasis-related genes in human colon cancer cells implanted into the cecum of nude mice. Oncol. Res. 8 (1996) 163-169
-
(1996)
Oncol. Res.
, vol.8
, pp. 163-169
-
-
Takahashi, Y.1
-
72
-
-
0021030275
-
Clinical and in vivo response following surgery or surgery plus adjuvant chemotherapy or immunotherapy for colorectal carcinoma in a rat model
-
House A.K., and Maley M.A. Clinical and in vivo response following surgery or surgery plus adjuvant chemotherapy or immunotherapy for colorectal carcinoma in a rat model. J. R. Soc. Med. 76 (1983) 833-840
-
(1983)
J. R. Soc. Med.
, vol.76
, pp. 833-840
-
-
House, A.K.1
Maley, M.A.2
-
73
-
-
33749334697
-
Using genetically engineered mouse models of cancer to aid drug development: an industry perspective
-
Singh M., and Johnson L. Using genetically engineered mouse models of cancer to aid drug development: an industry perspective. Clin. Cancer Res. 12 (2006) 5312-5328
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 5312-5328
-
-
Singh, M.1
Johnson, L.2
-
74
-
-
46749111024
-
Apc mice: models, modifiers and mutants
-
McCart A.E., et al. Apc mice: models, modifiers and mutants. Pathol. Res. Pract. 204 (2008) 479-490
-
(2008)
Pathol. Res. Pract.
, vol.204
, pp. 479-490
-
-
McCart, A.E.1
-
75
-
-
0142244181
-
Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases
-
Lin E.Y., et al. Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases. Am. J. Pathol. 163 (2003) 2113-2126
-
(2003)
Am. J. Pathol.
, vol.163
, pp. 2113-2126
-
-
Lin, E.Y.1
-
76
-
-
0026472124
-
Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease
-
Guy C.T., et al. Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease. Proc. Natl. Acad. Sci. U. S. A. 89 (1992) 10578-10582
-
(1992)
Proc. Natl. Acad. Sci. U. S. A.
, vol.89
, pp. 10578-10582
-
-
Guy, C.T.1
-
77
-
-
38549131901
-
GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model
-
Kouros-Mehr H., et al. GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model. Cancer Cell 13 (2008) 141-152
-
(2008)
Cancer Cell
, vol.13
, pp. 141-152
-
-
Kouros-Mehr, H.1
-
78
-
-
70350747593
-
Chemotherapy: adding oxaliplatin to the equation
-
Benson A.B. Chemotherapy: adding oxaliplatin to the equation. Nat. Rev. Clin. Oncol. 6 (2009) 620-622
-
(2009)
Nat. Rev. Clin. Oncol.
, vol.6
, pp. 620-622
-
-
Benson, A.B.1
-
79
-
-
77549088772
-
Pathways mediating VEGF-independent tumor angiogenesis
-
Rev, doi:10.1016/j.cytogfr.2009.11.003
-
Ferrara N. (2009) Pathways mediating VEGF-independent tumor angiogenesis. Cytokine Growth Factor Rev., doi:10.1016/j.cytogfr.2009.11.003
-
(2009)
Cytokine Growth Factor
-
-
Ferrara, N.1
-
80
-
-
66149147757
-
Initial safety report of NSABP C-08: A randomized phase III study of modified FOLFOX6 with or without bevacizumab for the adjuvant treatment of patients with stage II or III colon cancer
-
Allegra, C. et al. (2009) Initial safety report of NSABP C-08: a randomized phase III study of modified FOLFOX6 with or without bevacizumab for the adjuvant treatment of patients with stage II or III colon cancer. J. Clin. Oncol. 27, 3385-3390
-
(2009)
J. Clin. Oncol
, vol.27
, pp. 3385-3390
-
-
Allegra, C.1
-
81
-
-
60649106195
-
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
-
Paez-Ribes M., et al. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 15 (2009) 220-231
-
(2009)
Cancer Cell
, vol.15
, pp. 220-231
-
-
Paez-Ribes, M.1
-
82
-
-
57649112725
-
Deletion of vascular endothelial growth factor in myeloid cells accelerates tumorigenesis
-
Stockmann C., et al. Deletion of vascular endothelial growth factor in myeloid cells accelerates tumorigenesis. Nature 456 (2008) 814-818
-
(2008)
Nature
, vol.456
, pp. 814-818
-
-
Stockmann, C.1
|