-
1
-
-
0026364597
-
Systematics and evolution of spiders (Araneae)
-
Coddington, J.A.; Levi, H.W. Systematics and evolution of spiders (Araneae). Annu. Rev. Ecol. Syst. 1991, 22, 565-592.
-
(1991)
Annu. Rev. Ecol. Syst
, vol.22
, pp. 565-592
-
-
Coddington, J.A.1
Levi, H.W.2
-
2
-
-
1942470956
-
Clinical consequences of spider bite: Recent advances in our understanding
-
Isbister, G.K.; White, J. Clinical consequences of spider bite: recent advances in our understanding. Toxicon 2004, 43, 477-492.
-
(2004)
Toxicon
, vol.43
, pp. 477-492
-
-
Isbister, G.K.1
White, J.2
-
3
-
-
1942470961
-
The wonderful world of spiders: Preface to the special Toxicon issue on spider venoms
-
King, G.F. The wonderful world of spiders: preface to the special Toxicon issue on spider venoms. Toxicon 2004, 43, 471-476.
-
(2004)
Toxicon
, vol.43
, pp. 471-476
-
-
King, G.F.1
-
4
-
-
0033731951
-
Structure and pharmacology of spider venom neurotoxins
-
Escoubas, P.; Diochot, S.; Corzo, G. Structure and pharmacology of spider venom neurotoxins. Biochimie 2000, 82, 893-907.
-
(2000)
Biochimie
, vol.82
, pp. 893-907
-
-
Escoubas, P.1
Diochot, S.2
Corzo, G.3
-
5
-
-
0034768977
-
Pharmacology and biochemistry of spider venoms
-
Rash, L.D.; Hodgson, W.C. Pharmacology and biochemistry of spider venoms. Toxicon 2002, 40, 225-254.
-
(2002)
Toxicon
, vol.40
, pp. 225-254
-
-
Rash, L.D.1
Hodgson, W.C.2
-
6
-
-
1942534974
-
Australian funnel-web spiders: Master insecticide chemists
-
Tedford, H.W.; Sollod, B.L.; Maggio, F.; King, G.F. Australian funnel-web spiders: Master insecticide chemists. Toxicon 2004, 43, 601-618.
-
(2004)
Toxicon
, vol.43
, pp. 601-618
-
-
Tedford, H.W.1
Sollod, B.L.2
Maggio, F.3
King, G.F.4
-
7
-
-
1942438962
-
Tarantulas: Eight-legged pharmacists and combinatorial chemists
-
Escoubas, P.; Rash, L. Tarantulas: Eight-legged pharmacists and combinatorial chemists. Toxicon 2004, 43, 555-574.
-
(2004)
Toxicon
, vol.43
, pp. 555-574
-
-
Escoubas, P.1
Rash, L.2
-
8
-
-
33846918727
-
Spider venoms: A rich source of acylpolyamines and peptides as new leads for CNS drugs
-
Estrada, G.; Villegas, E.; Corzo, G. Spider venoms: a rich source of acylpolyamines and peptides as new leads for CNS drugs. Nat. Prod. Rep. 2007, 24, 145-161.
-
(2007)
Nat. Prod. Rep
, vol.24
, pp. 145-161
-
-
Estrada, G.1
Villegas, E.2
Corzo, G.3
-
9
-
-
74849097250
-
Molecular diversity of spider venom
-
Vassilevski, A.A.; Kozlov, S.A.; Grishin, E.V. Molecular diversity of spider venom. Biochemistry 2009, 74, 1505-1534.
-
(2009)
Biochemistry
, vol.74
, pp. 1505-1534
-
-
Vassilevski, A.A.1
Kozlov, S.A.2
Grishin, E.V.3
-
10
-
-
33646133193
-
Venom landscapes: Mining the complexity of spider venoms via a combined cDNA and mass spectrometric approach
-
Escoubas, P.; Sollod, B.; King, G.F. Venom landscapes: mining the complexity of spider venoms via a combined cDNA and mass spectrometric approach. Toxicon 2006, 47, 650-663.
-
(2006)
Toxicon
, vol.47
, pp. 650-663
-
-
Escoubas, P.1
Sollod, B.2
King, G.F.3
-
11
-
-
66949176303
-
Venomics as a drug discovery platform
-
Escoubas, P.; King, G.F. Venomics as a drug discovery platform. Expert Rev. Proteomics 2009, 6, 221-224.
-
(2009)
Expert Rev. Proteomics
, vol.6
, pp. 221-224
-
-
Escoubas, P.1
King, G.F.2
-
12
-
-
49449116956
-
A rational nomenclature for naming peptide toxins from spiders and other venomous animals
-
King, G.F.; Gentz, M.C.; Escoubas, P.; Nicholson, G.M. A rational nomenclature for naming peptide toxins from spiders and other venomous animals. Toxicon 2008, 52, 264-276.
-
(2008)
Toxicon
, vol.52
, pp. 264-276
-
-
King, G.F.1
Gentz, M.C.2
Escoubas, P.3
Nicholson, G.M.4
-
13
-
-
34250310496
-
Proteomic and peptidomic analysis of the venom from Chinese tarantula Chilobrachys jingzhao
-
Liao, Z.; Cao, J.; Li, S.; Yan, X.; Hu, W.; He, Q.; Chen, J.; Tang, J.; Xie, J.; Liang, S. Proteomic and peptidomic analysis of the venom from Chinese tarantula Chilobrachys jingzhao. Proteomics 2007, 7, 1892-1907.
-
(2007)
Proteomics
, vol.7
, pp. 1892-1907
-
-
Liao, Z.1
Cao, J.2
Li, S.3
Yan, X.4
Hu, W.5
He, Q.6
Chen, J.7
Tang, J.8
Xie, J.9
Liang, S.10
-
14
-
-
33645004061
-
Comparison of the partial proteomes of the venoms of Brazilian spiders of the genus Phoneutria
-
Richardson, M.; Pimenta, A.M.; Bemquerer, M.P.; Santoro, M.M.; Beirao, P.S.; Lima, M.E.; Figueiredo, S.G.; Bloch, C., Jr.; Vasconcelos, E.A.; Campos, F.A.; Gomes, P.C.; Cordeiro, M.N. Comparison of the partial proteomes of the venoms of Brazilian spiders of the genus Phoneutria. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 2006, 142, 173-187.
-
(2006)
Comp. Biochem. Physiol. C Toxicol. Pharmacol
, vol.142
, pp. 173-187
-
-
Richardson, M.1
Pimenta, A.M.2
Bemquerer, M.P.3
Santoro, M.M.4
Beirao, P.S.5
Lima, M.E.6
Figueiredo, S.G.7
Bloch Jr., C.8
Vasconcelos, E.A.9
Campos, F.A.10
Gomes, P.C.11
Cordeiro, M.N.12
-
15
-
-
46149096269
-
Transcriptome analysis of Loxosceles laeta (Araneae, Sicariidae) spider venomous gland using expressed sequence tags
-
de F Fernandes-Pedrosa, M.; de LM Junqueira-de-Azevedo, I.; Gonçalves-de-Andrade, R.M.; Kobashi, L.S.; Almeida, D.D.; Ho, P.L.; Tambourgi, D.V. Transcriptome analysis of Loxosceles laeta (Araneae, Sicariidae) spider venomous gland using expressed sequence tags. BMC Genomics 2008, 9, 279.
-
(2008)
BMC Genomics
, vol.9
, pp. 279
-
-
de Fernandes-Pedrosa, F.M.1
de Junqueira-de-Azevedo, L.M.I.2
Gonçalves-de-Andrade, R.M.3
Kobashi, L.S.4
Almeida, D.D.5
Ho, P.L.6
Tambourgi, D.V.7
-
16
-
-
44649108881
-
Molecular diversification based on analysis of expressed sequence tags from the venom glands of the Chinese bird spider Ornithoctonus huwena
-
Jiang, L.; Peng, L.; Chen, J.; Zhang, Y.; Xiong, X.; Liang, S. Molecular diversification based on analysis of expressed sequence tags from the venom glands of the Chinese bird spider Ornithoctonus huwena. Toxicon 2008, 51, 1479-1489.
-
(2008)
Toxicon
, vol.51
, pp. 1479-1489
-
-
Jiang, L.1
Peng, L.2
Chen, J.3
Zhang, Y.4
Xiong, X.5
Liang, S.6
-
17
-
-
14644397873
-
A novel strategy for the identification of toxinlike structures in spider venom
-
Kozlov, S.; Malyavka, A.; McCutchen, B.; Lu, A.; Schepers, E.; Herrmann, R.; Grishin, E. A novel strategy for the identification of toxinlike structures in spider venom. Proteins 2005, 59, 131-140.
-
(2005)
Proteins
, vol.59
, pp. 131-140
-
-
Kozlov, S.1
Malyavka, A.2
McCutchen, B.3
Lu, A.4
Schepers, E.5
Herrmann, R.6
Grishin, E.7
-
18
-
-
77955713622
-
Venom components from Citharischius crawshayi spider (Family Theraphosidae): Exploring transcriptome, venomics, and function
-
Diego-Garcia, E.; Peigneur, S.; Waelkens, E.; Debaveye, S.; Tytgat, J. Venom components from Citharischius crawshayi spider (Family Theraphosidae): Exploring transcriptome, venomics, and function. Cell. Mol. Life Sci. 2010, 67, 2799-2813.
-
(2010)
Cell. Mol. Life Sci
, vol.67
, pp. 2799-2813
-
-
Diego-Garcia, E.1
Peigneur, S.2
Waelkens, E.3
Debaveye, S.4
Tytgat, J.5
-
19
-
-
77952051544
-
Molecular diversification of peptide toxins from the tarantula Haplopelma hainanum (Ornithoctonus hainana) venom based on transcriptomic, peptidomic, and genomic analyses
-
Tang, X.; Zhang, Y.; Hu, W.; Xu, D.; Tao, H.; Yang, X.; Li, Y.; Jiang, L.; Liang, S. Molecular diversification of peptide toxins from the tarantula Haplopelma hainanum (Ornithoctonus hainana) venom based on transcriptomic, peptidomic, and genomic analyses. J. Proteome Res. 2010, 9, 2550-2564.
-
(2010)
J. Proteome Res
, vol.9
, pp. 2550-2564
-
-
Tang, X.1
Zhang, Y.2
Hu, W.3
Xu, D.4
Tao, H.5
Yang, X.6
Li, Y.7
Jiang, L.8
Liang, S.9
-
20
-
-
69549138138
-
ArachnoServer: A database of protein toxins from spiders
-
Wood, D.L.; Miljenovic, T.; Cai, S.; Raven, R.J.; Kaas, Q.; Escoubas, P.; Herzig, V.; Wilson, D.; King, G.F. ArachnoServer: A database of protein toxins from spiders. BMC Genomics 2009, 10, 375.
-
(2009)
BMC Genomics
, vol.10
, pp. 375
-
-
Wood, D.L.1
Miljenovic, T.2
Cai, S.3
Raven, R.J.4
Kaas, Q.5
Escoubas, P.6
Herzig, V.7
Wilson, D.8
King, G.F.9
-
21
-
-
78651279288
-
ArachnoServer 2.0, an updated online resource for spider toxin sequences and structures
-
doi:10.1093/nar/gkq1058
-
Herzig, V.; Wood, D.L.A.; Newell, F.; Chaumeil, P.-A.; Kaas, Q.; Binford, G.J.; Nicholson, G.M.; Gorse, D.; King, G.F. ArachnoServer 2.0, an updated online resource for spider toxin sequences and structures. Nucl. Acids Res. 2010, doi:10.1093/nar/gkq1058.
-
(2010)
Nucl. Acids Res
-
-
Herzig, V.1
Wood, D.L.A.2
Newell, F.3
Chaumeil, P.-A.4
Kaas, Q.5
Binford, G.J.6
Nicholson, G.M.7
Gorse, D.8
King, G.F.9
-
22
-
-
15244359951
-
Effects of spider Macrothele raven venom on cell proliferation and cytotoxicity in HeLa cells
-
Gao, L.; Shan, B.E.; Chen, J.; Liu, J.H.; Song, D.X.; Zhu, B.C. Effects of spider Macrothele raven venom on cell proliferation and cytotoxicity in HeLa cells. Acta Pharmacol. Sin. 2005, 26, 369-376.
-
(2005)
Acta Pharmacol. Sin
, vol.26
, pp. 369-376
-
-
Gao, L.1
Shan, B.E.2
Chen, J.3
Liu, J.H.4
Song, D.X.5
Zhu, B.C.6
-
23
-
-
34547111555
-
Effect of spider venom on cell apoptosis and necrosis rates in MCF-7 cells
-
Gao, L.; Yu, S.; Wu, Y.; Shan, B. Effect of spider venom on cell apoptosis and necrosis rates in MCF-7 cells. DNA Cell Biol. 2007, 26, 485-489.
-
(2007)
DNA Cell Biol
, vol.26
, pp. 485-489
-
-
Gao, L.1
Yu, S.2
Wu, Y.3
Shan, B.4
-
24
-
-
1942438974
-
The multiple actions of black widow spider toxins and their selective use in neurosecretion studies
-
Ushkaryov, Y.A.; Volynski, K.E.; Ashton, A.C. The multiple actions of black widow spider toxins and their selective use in neurosecretion studies. Toxicon 2004, 43, 527-542.
-
(2004)
Toxicon
, vol.43
, pp. 527-542
-
-
Ushkaryov, Y.A.1
Volynski, K.E.2
Ashton, A.C.3
-
25
-
-
0028811258
-
An inhibitor of the Kv2.1 potassium channel isolated from the venom of a Chilean tarantula
-
Swartz, K.J.; MacKinnon, R. An inhibitor of the Kv2.1 potassium channel isolated from the venom of a Chilean tarantula. Neuron 1995, 15, 941-949.
-
(1995)
Neuron
, vol.15
, pp. 941-949
-
-
Swartz, K.J.1
Mackinnon, R.2
-
26
-
-
1942438979
-
Agatoxins: Ion channel specific toxins from the American funnel web spider, Agelenopsis aperta
-
Adams, M.E. Agatoxins: Ion channel specific toxins from the American funnel web spider, Agelenopsis aperta. Toxicon 2004, 43, 509-525.
-
(2004)
Toxicon
, vol.43
, pp. 509-525
-
-
Adams, M.E.1
-
27
-
-
33847403885
-
Modulation of insect CaV channels by peptidic spider toxins
-
King, G.F. Modulation of insect CaV channels by peptidic spider toxins. Toxicon 2007, 49, 513-530.
-
(2007)
Toxicon
, vol.49
, pp. 513-530
-
-
King, G.F.1
-
28
-
-
49449095296
-
Peptide toxins that selectively target insect NaV and CaV channels
-
King, G.F.; Escoubas, P.; Nicholson, G.M. Peptide toxins that selectively target insect NaV and CaV channels. Channels 2008, 2, 100-116.
-
(2008)
Channels
, vol.2
, pp. 100-116
-
-
King, G.F.1
Escoubas, P.2
Nicholson, G.M.3
-
29
-
-
77951738339
-
Novel peptide from spider venom inhibits P2X3 receptors and inflammatory pain
-
Grishin, E.V.; Savchenko, G.A.; Vassilevski, A.A.; Korolkova, Y.V.; Boychuk, Y.A.; Viatchenko-Karpinski, V.Y.; Nadezhdin, K.D.; Arseniev, A.S.; Pluzhnikov, K.A.; Kulyk, V.B.; Voitenko, N.V.; Krishtal, O.O. Novel peptide from spider venom inhibits P2X3 receptors and inflammatory pain. Ann. Neurol. 2010, 67, 680-683.
-
(2010)
Ann. Neurol
, vol.67
, pp. 680-683
-
-
Grishin, E.V.1
Savchenko, G.A.2
Vassilevski, A.A.3
Korolkova, Y.V.4
Boychuk, Y.A.5
Viatchenko-Karpinski, V.Y.6
Nadezhdin, K.D.7
Arseniev, A.S.8
Pluzhnikov, K.A.9
Kulyk, V.B.10
Voitenko, N.V.11
Krishtal, O.O.12
-
30
-
-
0034682749
-
Isolation of a tarantula toxin specific for a class of proton-gated Na+ channels
-
Escoubas, P.; De Weille, J.R.; Lecoq, A.; Diochot, S.; Waldmann, R.; Champigny, G.; Moinier, D.; Menez, A.; Lazdunski, M. Isolation of a tarantula toxin specific for a class of proton-gated Na+ channels. J. Biol. Chem. 2000, 275, 25116-25121.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 25116-25121
-
-
Escoubas, P.1
de Weille, J.R.2
Lecoq, A.3
Diochot, S.4
Waldmann, R.5
Champigny, G.6
Moinier, D.7
Menez, A.8
Lazdunski, M.9
-
31
-
-
33846426807
-
Mechanosensitive ion channels and the peptide inhibitor GsMTx-4: History, properties, mechanisms and pharmacology
-
Bowman, C.L.; Gottlieb, P.A.; Suchyna, T.M.; Murphy, Y.K.; Sachs, F. Mechanosensitive ion channels and the peptide inhibitor GsMTx-4: history, properties, mechanisms and pharmacology. Toxicon 2007, 49, 249-270.
-
(2007)
Toxicon
, vol.49
, pp. 249-270
-
-
Bowman, C.L.1
Gottlieb, P.A.2
Suchyna, T.M.3
Murphy, Y.K.4
Sachs, F.5
-
32
-
-
33750873334
-
Spider toxins activate the capsaicin receptor to produce inflammatory pain
-
Siemens, J.; Zhou, S.; Piskorowski, R.; Nikai, T.; Lumpkin, E.A.; Basbaum, A.I.; King, D.; Julius, D. Spider toxins activate the capsaicin receptor to produce inflammatory pain. Nature 2006, 444, 208-212.
-
(2006)
Nature
, vol.444
, pp. 208-212
-
-
Siemens, J.1
Zhou, S.2
Piskorowski, R.3
Nikai, T.4
Lumpkin, E.A.5
Basbaum, A.I.6
King, D.7
Julius, D.8
-
33
-
-
34548081279
-
Spider peptide toxins as leads for drug development
-
Escoubas, P.; Bosmans, F. Spider peptide toxins as leads for drug development. Expert Opin. Drug Discov. 2007, 2, 823-835.
-
(2007)
Expert Opin. Drug Discov
, vol.2
, pp. 823-835
-
-
Escoubas, P.1
Bosmans, F.2
-
34
-
-
4644339418
-
Functional pharmacology: The drug discovery bottleneck
-
Walker, M.J.A.; Barrett, T.; Guppy, L.J. Functional pharmacology: The drug discovery bottleneck? Drug Discov. Today 2004, 3, 208-215.
-
(2004)
Drug Discov. Today
, vol.3
, pp. 208-215
-
-
Walker, M.J.A.1
Barrett, T.2
Guppy, L.J.3
-
35
-
-
51849116307
-
Druggable targets and targeted drugs: Enhancing the development of new therapeutics
-
Billingsley, M.L. Druggable targets and targeted drugs: enhancing the development of new therapeutics. Pharmacology 2008, 82, 239-244.
-
(2008)
Pharmacology
, vol.82
, pp. 239-244
-
-
Billingsley, M.L.1
-
36
-
-
78751571635
-
Venomics: A new paradigm for natural products-based drug discovery
-
doi:10.1007/s00726-00010-00516-00724
-
Vetter, I.; Davis, J.L.; Rash, L.D.; Anangi, R.; Mobli, M.; Alewood, P.F.; Lewis, R.J.; King, G.F. Venomics: a new paradigm for natural products-based drug discovery. Amino Acids 2010, doi:10.1007/s00726-00010-00516-00724.
-
(2010)
Amino Acids
-
-
Vetter, I.1
Davis, J.L.2
Rash, L.D.3
Anangi, R.4
Mobli, M.5
Alewood, P.F.6
Lewis, R.J.7
King, G.F.8
-
37
-
-
70450203818
-
The medicinal chemistry of peptides
-
Nestor, J.J., Jr. The medicinal chemistry of peptides. Curr. Med. Chem. 2009, 16, 4399-4418.
-
(2009)
Curr. Med. Chem
, vol.16
, pp. 4399-4418
-
-
Nestor Jr., J.J.1
-
38
-
-
22244488749
-
Oral delivery of peptide drugs: Barriers and developments
-
Hamman, J.H.; Enslin, G.M.; Kotze, A.F. Oral delivery of peptide drugs: Barriers and developments. BioDrugs 2005, 19, 165-177.
-
(2005)
BioDrugs
, vol.19
, pp. 165-177
-
-
Hamman, J.H.1
Enslin, G.M.2
Kotze, A.F.3
-
39
-
-
0028090517
-
A common structural motif incorporating a cystine knot and a triple-stranded β-sheet in toxic and inhibitory polypeptides
-
Pallaghy, P.K.; Nielsen, K.J.; Craik, D.J.; Norton, R.S. A common structural motif incorporating a cystine knot and a triple-stranded β-sheet in toxic and inhibitory polypeptides. Protein Sci. 1994, 3, 1833-1839.
-
(1994)
Protein Sci
, vol.3
, pp. 1833-1839
-
-
Pallaghy, P.K.1
Nielsen, K.J.2
Craik, D.J.3
Norton, R.S.4
-
40
-
-
0031796848
-
The cystine knot structure of ion channel toxins and related polypeptides
-
Norton, R.S.; Pallaghy, P.K. The cystine knot structure of ion channel toxins and related polypeptides. Toxicon 1998, 36, 1573-1583.
-
(1998)
Toxicon
, vol.36
, pp. 1573-1583
-
-
Norton, R.S.1
Pallaghy, P.K.2
-
41
-
-
0036447597
-
Structure and function of insecticidal neurotoxins from Australian funnel-web spiders
-
King, G.F.; Tedford, H.W.; Maggio, F. Structure and function of insecticidal neurotoxins from Australian funnel-web spiders. J. Toxicol. Toxin Rev. 2002, 21, 359-389.
-
(2002)
J. Toxicol. Toxin Rev
, vol.21
, pp. 359-389
-
-
King, G.F.1
Tedford, H.W.2
Maggio, F.3
-
42
-
-
0030727613
-
The structure of versutoxin (δ-atracotoxin-Hv1) provides insights into the binding of site 3 neurotoxins to the voltage-gated sodium channel
-
Fletcher, J.I.; Chapman, B.E.; Mackay, J.P.; Howden, M.E.H.; King, G.F. The structure of versutoxin (δ-atracotoxin-Hv1) provides insights into the binding of site 3 neurotoxins to the voltage-gated sodium channel. Structure 1997, 5, 1525-1535.
-
(1997)
Structure
, vol.5
, pp. 1525-1535
-
-
Fletcher, J.I.1
Chapman, B.E.2
Mackay, J.P.3
Howden, M.E.H.4
King, G.F.5
-
43
-
-
0030981657
-
The structure of a novel insecticidal neurotoxin, ω-atracotoxin-HV1, from the venom of an Australian funnel web spider
-
Fletcher, J.I.; Smith, R.; O'Donoghue, S.I.; Nilges, M.; Connor, M.; Howden, M.E.H.; Christie, M.J.; King, G.F. The structure of a novel insecticidal neurotoxin, ω-atracotoxin-HV1, from the venom of an Australian funnel web spider. Nat. Struct. Biol. 1997, 4, 559-566.
-
(1997)
Nat. Struct. Biol
, vol.4
, pp. 559-566
-
-
Fletcher, J.I.1
Smith, R.2
O'Donoghue, S.I.3
Nilges, M.4
Connor, M.5
Howden, M.E.H.6
Christie, M.J.7
King, G.F.8
-
44
-
-
0035239222
-
The cystine knot motif in toxins and implications for drug design
-
Craik, D.J.; Daly, N.L.; Waine, C. The cystine knot motif in toxins and implications for drug design. Toxicon 2001, 39, 43-60.
-
(2001)
Toxicon
, vol.39
, pp. 43-60
-
-
Craik, D.J.1
Daly, N.L.2
Waine, C.3
-
45
-
-
2442715239
-
Thermal, chemical, and enzymatic stability of the cyclotide kalata B1: The importance of the cyclic cystine knot
-
Colgrave, M.L.; Craik, D.J. Thermal, chemical, and enzymatic stability of the cyclotide kalata B1: The importance of the cyclic cystine knot. Biochemistry 2004, 43, 5965-5975.
-
(2004)
Biochemistry
, vol.43
, pp. 5965-5975
-
-
Colgrave, M.L.1
Craik, D.J.2
-
46
-
-
0037145909
-
Digestibility of food allergens and nonallergenic proteins in simulated gastric fluid and simulated intestinal fluid-A comparative study
-
Fu, T.J.; Abbott, U.R.; Hatzos, C. Digestibility of food allergens and nonallergenic proteins in simulated gastric fluid and simulated intestinal fluid-A comparative study. J. Agric. Food Chem. 2002, 50, 7154-7160.
-
(2002)
J. Agric. Food Chem
, vol.50
, pp. 7154-7160
-
-
Fu, T.J.1
Abbott, U.R.2
Hatzos, C.3
-
47
-
-
77956502216
-
The engineering of an orally active conotoxin for the treatment of neuropathic pain
-
Clark, R.J.; Jensen, J.; Nevin, S.T.; Callaghan, B.P.; Adams, D.J.; Craik, D.J. The engineering of an orally active conotoxin for the treatment of neuropathic pain. Angew. Chem. Int. Ed. 2010, 49, 6545-6548.
-
(2010)
Angew. Chem. Int. Ed
, vol.49
, pp. 6545-6548
-
-
Clark, R.J.1
Jensen, J.2
Nevin, S.T.3
Callaghan, B.P.4
Adams, D.J.5
Craik, D.J.6
-
48
-
-
11144319833
-
Were arachnids the first to use combinatorial peptide libraries?
-
Sollod, B.L.; Wilson, D.; Zhaxybayeva, O.; Gogarten, J.P.; Drinkwater, R.; King, G.F. Were arachnids the first to use combinatorial peptide libraries? Peptides 2005, 26, 131-139.
-
(2005)
Peptides
, vol.26
, pp. 131-139
-
-
Sollod, B.L.1
Wilson, D.2
Zhaxybayeva, O.3
Gogarten, J.P.4
Drinkwater, R.5
King, G.F.6
-
49
-
-
34250860086
-
Pain management: A fundamental human right
-
Brennan, F.; Carr, D.B.; Cousins, M. Pain management: A fundamental human right. Anesth. Analg. 2007, 105, 205-221.
-
(2007)
Anesth. Analg
, vol.105
, pp. 205-221
-
-
Brennan, F.1
Carr, D.B.2
Cousins, M.3
-
51
-
-
0036307827
-
Epithelial sodium channel/degenerin family of ion channels: A variety of functions for a shared structure
-
Kellenberger, S.; Schild, L. Epithelial sodium channel/degenerin family of ion channels: A variety of functions for a shared structure. Physiol. Rev. 2002, 82, 735-767.
-
(2002)
Physiol. Rev
, vol.82
, pp. 735-767
-
-
Kellenberger, S.1
Schild, L.2
-
52
-
-
34547101720
-
Acid-sensing ion channels in sensory perception
-
Lingueglia, E. Acid-sensing ion channels in sensory perception. J. Biol. Chem. 2007, 282, 17325-17329.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 17325-17329
-
-
Lingueglia, E.1
-
53
-
-
77954727554
-
Structure, function, and pharmacology of acid-sensing ion channels (ASICs): Focus on ASIC1a
-
Gründer, S.; Chen, X. Structure, function, and pharmacology of acid-sensing ion channels (ASICs): Focus on ASIC1a. Int. J. Physiol. Pathophysiol. Pharmacol. 2010, 2, 73-94.
-
(2010)
Int. J. Physiol. Pathophysiol. Pharmacol
, vol.2
, pp. 73-94
-
-
Gründer, S.1
Chen, X.2
-
54
-
-
33748797928
-
Acid-sensing ion channels: Advances, questions and therapeutic opportunities
-
Wemmie, J.A.; Price, M.P.; Welsh, M.J. Acid-sensing ion channels: Advances, questions and therapeutic opportunities. Trends Neurosci. 2006, 29, 578-586.
-
(2006)
Trends Neurosci
, vol.29
, pp. 578-586
-
-
Wemmie, J.A.1
Price, M.P.2
Welsh, M.J.3
-
55
-
-
38649129918
-
Acid-sensing ion channels (ASICs) as pharmacological targets for neurodegenerative diseases
-
Xiong, Z.G.; Pignataro, G.; Li, M.; Chang, S.Y.; Simon, R.P. Acid-sensing ion channels (ASICs) as pharmacological targets for neurodegenerative diseases. Curr. Opin. Pharmacol. 2008, 8, 25-32.
-
(2008)
Curr. Opin. Pharmacol
, vol.8
, pp. 25-32
-
-
Xiong, Z.G.1
Pignataro, G.2
Li, M.3
Chang, S.Y.4
Simon, R.P.5
-
56
-
-
70149084337
-
Acid-sensing ion channels: A new target for pain and CNS diseases
-
Sluka, K.A.; Winter, O.C.; Wemmie, J.A. Acid-sensing ion channels: a new target for pain and CNS diseases. Curr. Opin. Drug Discov. Devel. 2009, 12, 693-704.
-
(2009)
Curr. Opin. Drug Discov. Devel
, vol.12
, pp. 693-704
-
-
Sluka, K.A.1
Winter, O.C.2
Wemmie, J.A.3
-
57
-
-
34547502749
-
A tarantula peptide against pain via ASIC1a channels and opioid mechanisms
-
Mazzuca, M.; Heurteaux, C.; Alloui, A.; Diochot, S.; Baron, A.; Voilley, N.; Blondeau, N.; Escoubas, P.; Gelot, A.; Cupo, A.; Zimmer, A.; Zimmer, A.M.; Eschalier, A.; Lazdunski, M. A tarantula peptide against pain via ASIC1a channels and opioid mechanisms. Nat. Neurosci. 2007, 10, 943-945.
-
(2007)
Nat. Neurosci
, vol.10
, pp. 943-945
-
-
Mazzuca, M.1
Heurteaux, C.2
Alloui, A.3
Diochot, S.4
Baron, A.5
Voilley, N.6
Blondeau, N.7
Escoubas, P.8
Gelot, A.9
Cupo, A.10
Zimmer, A.11
Zimmer, A.M.12
Eschalier, A.13
Lazdunski, M.14
-
58
-
-
33845897638
-
Prolonged activation of ASIC1a and the time window for neuroprotection in cerebral ischaemia
-
Pignataro, G.; Simon, R.P.; Xiong, Z.G. Prolonged activation of ASIC1a and the time window for neuroprotection in cerebral ischaemia. Brain 2007, 130, 151-158.
-
(2007)
Brain
, vol.130
, pp. 151-158
-
-
Pignataro, G.1
Simon, R.P.2
Xiong, Z.G.3
-
59
-
-
43649103172
-
Intrathecal drug delivery
-
Smith, H.S.; Deer, T.R.; Staats, P.S.; Singh, V.; Sehgal, N.; Cordner, H. Intrathecal drug delivery. Pain Physician 2008, 11, S89-S104.
-
(2008)
Pain Physician
, vol.11
-
-
Smith, H.S.1
Deer, T.R.2
Staats, P.S.3
Singh, V.4
Sehgal, N.5
Cordner, H.6
-
60
-
-
77952237542
-
Intrathecal therapy: What has changed with the introduction of ziconotide
-
Kress, H.G.; Simpson, K.H.; Marchettini, P.; Ver Donck, A.; Varrassi, G. Intrathecal therapy: what has changed with the introduction of ziconotide. Pain Pract. 2009, 9, 338-347.
-
(2009)
Pain Pract
, vol.9
, pp. 338-347
-
-
Kress, H.G.1
Simpson, K.H.2
Marchettini, P.3
Ver, D.A.4
Varrassi, G.5
-
61
-
-
67650543860
-
Psalmotoxin-1 docking to human acid-sensing ion channel-1
-
Qadri, Y.J.; Berdiev, B.K.; Song, Y.; Lippton, H.L.; Fuller, C.M.; Benos, D.J. Psalmotoxin-1 docking to human acid-sensing ion channel-1. J. Biol. Chem. 2009, 284, 17625-17633.
-
(2009)
J. Biol. Chem
, vol.284
, pp. 17625-17633
-
-
Qadri, Y.J.1
Berdiev, B.K.2
Song, Y.3
Lippton, H.L.4
Fuller, C.M.5
Benos, D.J.6
-
62
-
-
66149131772
-
Docking and MD simulations of the interaction of the tarantula peptide psalmotoxin-1 with ASIC1a channels using a homology model
-
Pietra, F. Docking and MD simulations of the interaction of the tarantula peptide psalmotoxin-1 with ASIC1a channels using a homology model. J. Chem. Inf. Model. 2009, 49, 972-977.
-
(2009)
J. Chem. Inf. Model
, vol.49
, pp. 972-977
-
-
Pietra, F.1
-
63
-
-
0037264170
-
Overview of the voltage-gated sodium channel family
-
Yu, F.H.; Catterall, W.A. Overview of the voltage-gated sodium channel family. Genome Biol. 2003, 4, 207.
-
(2003)
Genome Biol
, vol.4
, pp. 207
-
-
Yu, F.H.1
Catterall, W.A.2
-
64
-
-
38649130197
-
Sodium channels and nociception: Recent concepts and therapeutic opportunities
-
Krafte, D.S.; Bannon, A.W. Sodium channels and nociception: Recent concepts and therapeutic opportunities. Current Opin. Pharmacol. 2008, 8, 50-56.
-
(2008)
Current Opin. Pharmacol
, vol.8
, pp. 50-56
-
-
Krafte, D.S.1
Bannon, A.W.2
-
65
-
-
70149097762
-
Future potential and status of selective sodium channel blockers for the treatment of pain
-
Priest, B.T. Future potential and status of selective sodium channel blockers for the treatment of pain. Curr. Opin. Drug Discov. Devel. 2009, 12, 682-692.
-
(2009)
Curr. Opin. Drug Discov. Devel
, vol.12
, pp. 682-692
-
-
Priest, B.T.1
-
66
-
-
12144288410
-
Mutations in SCN9A, encoding a sodium channel alpha subunit, in patients with primary erythermalgia
-
Yang, Y.; Wang, Y.; Li, S.; Xu, Z.; Li, H.; Ma, L.; Fan, J.; Bu, D.; Liu, B.; Fan, Z.; Wu, G.; Jin, J.; Ding, B.; Zhu, X.; Shen, Y. Mutations in SCN9A, encoding a sodium channel alpha subunit, in patients with primary erythermalgia. J. Med. Genet. 2004, 41, 171-174.
-
(2004)
J. Med. Genet
, vol.41
, pp. 171-174
-
-
Yang, Y.1
Wang, Y.2
Li, S.3
Xu, Z.4
Li, H.5
Ma, L.6
Fan, J.7
Bu, D.8
Liu, B.9
Fan, Z.10
Wu, G.11
Jin, J.12
Ding, B.13
Zhu, X.14
Shen, Y.15
-
67
-
-
33847168937
-
SCN9A mutations in paroxysmal extreme pain disorder: Allelic variants underlie distinct channel defects and phenotypes
-
Fertleman, C.R.; Baker, M.D.; Parker, K.A.; Moffatt, S.; Elmslie, F.V.; Abrahamsen, B.; Ostman, J.; Klugbauer, N.; Wood, J.N.; Gardiner, R.M.; Rees, M. SCN9A mutations in paroxysmal extreme pain disorder: Allelic variants underlie distinct channel defects and phenotypes. Neuron 2006, 52, 767-774.
-
(2006)
Neuron
, vol.52
, pp. 767-774
-
-
Fertleman, C.R.1
Baker, M.D.2
Parker, K.A.3
Moffatt, S.4
Elmslie, F.V.5
Abrahamsen, B.6
Ostman, J.7
Klugbauer, N.8
Wood, J.N.9
Gardiner, R.M.10
Rees, M.11
-
68
-
-
33845901486
-
An SCN9A channelopathy causes congenital inability to experience pain
-
Cox, J.J.; Reimann, F.; Nicholas, A.K.; Thornton, G.; Roberts, E.; Springell, K.; Karbani, G.; Jafri, H.; Mannan, J.; Raashid, Y.; Al-Gazali, L.; Hamamy, H.; Valente, E.M.; Gorman, S.; Williams, R.; McHale, D.P.; Wood, J.N.; Gribble, F.M.; Woods, C.G. An SCN9A channelopathy causes congenital inability to experience pain. Nature 2006, 444, 894-898.
-
(2006)
Nature
, vol.444
, pp. 894-898
-
-
Cox, J.J.1
Reimann, F.2
Nicholas, A.K.3
Thornton, G.4
Roberts, E.5
Springell, K.6
Karbani, G.7
Jafri, H.8
Mannan, J.9
Raashid, Y.10
Al-Gazali, L.11
Hamamy, H.12
Valente, E.M.13
Gorman, S.14
Williams, R.15
McHale, D.P.16
Wood, J.N.17
Gribble, F.M.18
Woods, C.G.19
-
69
-
-
34247874778
-
Loss-of-function mutations in the NaV1.7 gene underlie congenital indifference to pain in multiple human populations
-
Goldberg, Y.P.; MacFarlane, J.; MacDonald, M.L.; Thompson, J.; Dube, M.P.; Mattice, M.; Fraser, R.; Young, C.; Hossain, S.; Pape, T.; Payne, B.; Radomski, C.; Donaldson, G.; Ives, E.; Cox, J.; Younghusband, H.B.; Green, R.; Duff, A.; Boltshauser, E.; Grinspan, G.A.; Dimon, J.H.; Sibley, B.G.; Andria, G.; Toscano, E.; Kerdraon, J.; Bowsher, D.; Pimstone, S.N.; Samuels, M.E.; Sherrington, R.; Hayden, M.R. Loss-of-function mutations in the NaV1.7 gene underlie congenital indifference to pain in multiple human populations. Clin. Genet. 2007, 71, 311-319.
-
(2007)
Clin. Genet
, vol.71
, pp. 311-319
-
-
Goldberg, Y.P.1
Macfarlane, J.2
Macdonald, M.L.3
Thompson, J.4
Dube, M.P.5
Mattice, M.6
Fraser, R.7
Young, C.8
Hossain, S.9
Pape, T.10
Payne, B.11
Radomski, C.12
Donaldson, G.13
Ives, E.14
Cox, J.15
Younghusband, H.B.16
Green, R.17
Duff, A.18
Boltshauser, E.19
Grinspan, G.A.20
Dimon, J.H.21
Sibley, B.G.22
Andria, G.23
Toscano, E.24
Kerdraon, J.25
Bowsher, D.26
Pimstone, S.N.27
Samuels, M.E.28
Sherrington, R.29
Hayden, M.R.30
more..
-
70
-
-
63449141978
-
Two novel SCN9A mutations causing insensitivity to pain
-
Nilsen, K.B.; Nicholas, A.K.; Woods, C.G.; Mellgren, S.I.; Nebuchennykh, M.; Aasly, J. Two novel SCN9A mutations causing insensitivity to pain. Pain 2009, 143, 155-158.
-
(2009)
Pain
, vol.143
, pp. 155-158
-
-
Nilsen, K.B.1
Nicholas, A.K.2
Woods, C.G.3
Mellgren, S.I.4
Nebuchennykh, M.5
Aasly, J.6
-
71
-
-
72049087523
-
Targeting voltage-gated sodium channels for pain therapy
-
Clare, J.J. Targeting voltage-gated sodium channels for pain therapy. Expert Opin. Invest. Drugs 2010, 19, 45-62.
-
(2010)
Expert Opin. Invest. Drugs
, vol.19
, pp. 45-62
-
-
Clare, J.J.1
-
72
-
-
79952082730
-
Spider toxins and their potential for insect control
-
Gilbert, L.I.; Gill, S.S., Eds.; Academic Press: London, UK
-
Maggio, F.; Sollod, B.L.; Tedford, H.W.; Herzig, V.; King, G.F. Spider toxins and their potential for insect control. In Insect Pharmacology: Channels, Receptors, Toxins and Enzymes; Gilbert, L.I.; Gill, S.S., Eds.; Academic Press: London, UK, 2010; pp. 101-123.
-
(2010)
Insect Pharmacology: Channels, Receptors, Toxins and Enzymes
, pp. 101-123
-
-
Maggio, F.1
Sollod, B.L.2
Tedford, H.W.3
Herzig, V.4
King, G.F.5
-
73
-
-
0037126684
-
Two tarantula peptides inhibit activation of multiple sodium channels
-
Middleton, R.E.; Warren, V.A.; Kraus, R.L.; Hwang, J.C.; Liu, C.J.; Dai, G.; Brochu, R.M.; Kohler, M.G.; Gao, Y.D.; Garsky, V.M.; Bogusky, M.J.; Mehl, J.T.; Cohen, C.J.; Smith, M.M. Two tarantula peptides inhibit activation of multiple sodium channels. Biochemistry 2002, 41, 14734-14747.
-
(2002)
Biochemistry
, vol.41
, pp. 14734-14747
-
-
Middleton, R.E.1
Warren, V.A.2
Kraus, R.L.3
Hwang, J.C.4
Liu, C.J.5
Dai, G.6
Brochu, R.M.7
Kohler, M.G.8
Gao, Y.D.9
Garsky, V.M.10
Bogusky, M.J.11
Mehl, J.T.12
Cohen, C.J.13
Smith, M.M.14
-
74
-
-
54349114035
-
ProTx-II, a selective inhibitor of NaV1.7 sodium channels, blocks action potential propagation in nociceptors
-
Schmalhofer, W.A.; Calhoun, J.; Burrows, R.; Bailey, T.; Kohler, M.G.; Weinglass, A.B.; Kaczorowski, G.J.; Garcia, M.L.; Koltzenburg, M.; Priest, B.T. ProTx-II, a selective inhibitor of NaV1.7 sodium channels, blocks action potential propagation in nociceptors. Mol. Pharmacol. 2008, 74, 1476-1484.
-
(2008)
Mol. Pharmacol
, vol.74
, pp. 1476-1484
-
-
Schmalhofer, W.A.1
Calhoun, J.2
Burrows, R.3
Bailey, T.4
Kohler, M.G.5
Weinglass, A.B.6
Kaczorowski, G.J.7
Garcia, M.L.8
Koltzenburg, M.9
Priest, B.T.10
-
76
-
-
33746701380
-
P2X receptors as cell-surface ATP sensors in health and disease
-
Khakh, B.S.; North, R.A. P2X receptors as cell-surface ATP sensors in health and disease. Nature 2006, 442, 527-532.
-
(2006)
Nature
, vol.442
, pp. 527-532
-
-
Khakh, B.S.1
North, R.A.2
-
77
-
-
76149099290
-
The P2X7 purinergic receptor: From physiology to neurological disorders
-
Skaper, S.D.; Debetto, P.; Giusti, P. The P2X7 purinergic receptor: from physiology to neurological disorders. FASEB J. 2010, 24, 337-345.
-
(2010)
FASEB J
, vol.24
, pp. 337-345
-
-
Skaper, S.D.1
Debetto, P.2
Giusti, P.3
-
78
-
-
0032089620
-
P2X1 and P2X3 receptors form stable trimers: A novel structural motif of ligand-gated ion channels
-
Nicke, A.; Baumert, H.G.; Rettinger, J.; Eichele, A.; Lambrecht, G.; Mutschler, E.; Schmalzing, G. P2X1 and P2X3 receptors form stable trimers: a novel structural motif of ligand-gated ion channels. EMBO J. 1998, 17, 3016-3028
-
(1998)
EMBO J
, vol.17
, pp. 3016-3028
-
-
Nicke, A.1
Baumert, H.G.2
Rettinger, J.3
Eichele, A.4
Lambrecht, G.5
Mutschler, E.6
Schmalzing, G.7
-
79
-
-
38449111937
-
P2X3 receptor involvement in pain states
-
Wirkner, K.; Sperlagh, B.; Illes, P. P2X3 receptor involvement in pain states. Mol. Neurobiol. 2007, 36, 165-183.
-
(2007)
Mol. Neurobiol
, vol.36
, pp. 165-183
-
-
Wirkner, K.1
Sperlagh, B.2
Illes, P.3
-
80
-
-
0042968804
-
P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury
-
Tsuda, M.; Shigemoto-Mogami, Y.; Koizumi, S.; Mizokoshi, A.; Kohsaka, S.; Salter, M.W.; Inoue, K. P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury. Nature 2003, 424, 778-783.
-
(2003)
Nature
, vol.424
, pp. 778-783
-
-
Tsuda, M.1
Shigemoto-Mogami, Y.2
Koizumi, S.3
Mizokoshi, A.4
Kohsaka, S.5
Salter, M.W.6
Inoue, K.7
-
81
-
-
77951590103
-
P2X purinergic receptor ligands: Recently patented compounds
-
Gunosewoyo, H.; Kassiou, M. P2X purinergic receptor ligands: recently patented compounds. Expert Opin. Ther. Pat. 2010, 20, 625-646.
-
(2010)
Expert Opin. Ther. Pat
, vol.20
, pp. 625-646
-
-
Gunosewoyo, H.1
Kassiou, M.2
-
82
-
-
0842344649
-
P2X3 receptors and peripheral pain mechanisms
-
North, R.A. P2X3 receptors and peripheral pain mechanisms. J. Physiol. 2004, 554, 301-308.
-
(2004)
J. Physiol
, vol.554
, pp. 301-308
-
-
North, R.A.1
-
83
-
-
0037168683
-
A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat
-
Jarvis, M.F.; Burgard, E.C.; McGaraughty, S.; Honore, P.; Lynch, K.; Brennan, T.J.; Subieta, A.; Van Biesen, T.; Cartmell, J.; Bianchi, B.; Niforatos, W.; Kage, K.; Yu, H.; Mikusa, J.; Wismer, C.T.; Zhu, C.Z.; Chu, K.; Lee, C.H.; Stewart, A.O.; Polakowski, J.; Cox, B.F.; Kowaluk, E.; Williams, M.; Sullivan, J.; Faltynek, C. A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat. Proc. Natl. Acad. Sci. USA 2002, 99, 17179-17184.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 17179-17184
-
-
Jarvis, M.F.1
Burgard, E.C.2
McGaraughty, S.3
Honore, P.4
Lynch, K.5
Brennan, T.J.6
Subieta, A.7
van Biesen, T.8
Cartmell, J.9
Bianchi, B.10
Niforatos, W.11
Kage, K.12
Yu, H.13
Mikusa, J.14
Wismer, C.T.15
Zhu, C.Z.16
Chu, K.17
Lee, C.H.18
Stewart, A.O.19
Polakowski, J.20
Cox, B.F.21
Kowaluk, E.22
Williams, M.23
Sullivan, J.24
Faltynek, C.25
more..
-
84
-
-
33745146902
-
The suramin analog 4,4',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis (carbonylimino)))tetra-kis-benzenesulfonic acid (NF110) potently blocks P2X3 receptors: Subtype selectivity is determined by location of sulfonic acid groups
-
Hausmann, R.; Rettinger, J.; Gerevich, Z.; Meis, S.; Kassack, M.U.; Illes, P.; Lambrecht, G.; Schmalzing, G. The suramin analog 4,4',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis (carbonylimino)))tetra-kis-benzenesulfonic acid (NF110) potently blocks P2X3 receptors: Subtype selectivity is determined by location of sulfonic acid groups. Mol. Pharmacol. 2006, 69, 2058-2067.
-
(2006)
Mol. Pharmacol
, vol.69
, pp. 2058-2067
-
-
Hausmann, R.1
Rettinger, J.2
Gerevich, Z.3
Meis, S.4
Kassack, M.U.5
Illes, P.6
Lambrecht, G.7
Schmalzing, G.8
-
85
-
-
34548494816
-
Structure-activity relationship studies of spinorphin as a potent and selective human P2X(3) receptor antagonist
-
Jung, K.Y.; Moon, H.D.; Lee, G.E.; Lim, H.H.; Park, C.S.; Kim, Y.C. Structure-activity relationship studies of spinorphin as a potent and selective human P2X(3) receptor antagonist. J. Med. Chem. 2007, 50, 4543-4547.
-
(2007)
J. Med. Chem
, vol.50
, pp. 4543-4547
-
-
Jung, K.Y.1
Moon, H.D.2
Lee, G.E.3
Lim, H.H.4
Park, C.S.5
Kim, Y.C.6
-
86
-
-
9144272640
-
Ziconotide: Neuronal calcium channel blocker for treating severe chronic pain
-
Miljanich, G.P. Ziconotide: neuronal calcium channel blocker for treating severe chronic pain. Curr. Med. Chem. 2004, 11, 3029-3040.
-
(2004)
Curr. Med. Chem
, vol.11
, pp. 3029-3040
-
-
Miljanich, G.P.1
-
87
-
-
17944378645
-
Two new classes of conopeptides inhibit the α1-adrenoceptor and noradrenaline transporter
-
Sharpe, I.A.; Gehrmann, J.; Loughnan, M.L.; Thomas, L.; Adams, D.A.; Atkins, A.; Palant, E.; Craik, D.J.; Adams, D.J.; Alewood, P.F.; Lewis, R.J. Two new classes of conopeptides inhibit the α1-adrenoceptor and noradrenaline transporter. Nat. Neurosci. 2001, 4, 902-907.
-
(2001)
Nat. Neurosci
, vol.4
, pp. 902-907
-
-
Sharpe, I.A.1
Gehrmann, J.2
Loughnan, M.L.3
Thomas, L.4
Adams, D.A.5
Atkins, A.6
Palant, E.7
Craik, D.J.8
Adams, D.J.9
Alewood, P.F.10
Lewis, R.J.11
-
88
-
-
58149200910
-
Transient receptor potential channels: Targeting pain at the source
-
Patapoutian, A.; Tate, S.; Woolf, C.J. Transient receptor potential channels: Targeting pain at the source. Nat. Rev. Drug Discov. 2009, 8, 55-68.
-
(2009)
Nat. Rev. Drug Discov
, vol.8
, pp. 55-68
-
-
Patapoutian, A.1
Tate, S.2
Woolf, C.J.3
-
90
-
-
0038026045
-
Evolutionary origins of mechanosensitive ion channels
-
Martinac, B.; Kloda, A. Evolutionary origins of mechanosensitive ion channels. Prog. Biophys. Mol. Biol. 2003, 82, 11-24.
-
(2003)
Prog. Biophys. Mol. Biol
, vol.82
, pp. 11-24
-
-
Martinac, B.1
Kloda, A.2
-
91
-
-
76349102806
-
Stretch-activated ion channels: What are they
-
Sachs, F. Stretch-activated ion channels: What are they? Physiology 2010, 25, 50-56.
-
(2010)
Physiology
, vol.25
, pp. 50-56
-
-
Sachs, F.1
-
92
-
-
0034103610
-
Identification of a peptide toxin from Grammostola spatulata spider venom that blocks cation-selective stretch-activated channels
-
Suchyna, T.M.; Johnson, J.H.; Hamer, K.; Leykam, J.F.; Gage, D.A.; Clemo, H.F.; Baumgarten, C.M.; Sachs, F. Identification of a peptide toxin from Grammostola spatulata spider venom that blocks cation-selective stretch-activated channels. J. Gen. Physiol. 2000, 115, 583-598.
-
(2000)
J. Gen. Physiol
, vol.115
, pp. 583-598
-
-
Suchyna, T.M.1
Johnson, J.H.2
Hamer, K.3
Leykam, J.F.4
Gage, D.A.5
Clemo, H.F.6
Baumgarten, C.M.7
Sachs, F.8
-
93
-
-
0037072815
-
Solution structure of peptide toxins that block mechanosensitive ion channels
-
Oswald, R.E.; Suchyna, T.M.; McFeeters, R.; Gottlieb, P.; Sachs, F. Solution structure of peptide toxins that block mechanosensitive ion channels. J. Biol. Chem. 2002, 277, 34443-34450.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 34443-34450
-
-
Oswald, R.E.1
Suchyna, T.M.2
McFeeters, R.3
Gottlieb, P.4
Sachs, F.5
-
94
-
-
0035804258
-
Tarantula peptide inhibits atrial fibrillation
-
Bode, F.; Sachs, F.; Franz, M.R. Tarantula peptide inhibits atrial fibrillation. Nature 2001, 409, 35-36.
-
(2001)
Nature
, vol.409
, pp. 35-36
-
-
Bode, F.1
Sachs, F.2
Franz, M.R.3
-
95
-
-
3142652571
-
Bilayer-dependent inhibition of mechanosensitive channels by neuroactive peptide enantiomers
-
Suchyna, T.M.; Tape, S.E.; Koeppe, R.E., 2nd; Andersen, O.S.; Sachs, F.; Gottlieb, P.A. Bilayer-dependent inhibition of mechanosensitive channels by neuroactive peptide enantiomers. Nature 2004, 430, 235-240.
-
(2004)
Nature
, vol.430
, pp. 235-240
-
-
Suchyna, T.M.1
Tape, S.E.2
Koeppe, R.E.3
Andersen, O.S.4
Sachs, F.5
Gottlieb, P.A.6
-
96
-
-
3142580388
-
Ion channels: Gate expectations
-
Garcia, M.L. Ion channels: Gate expectations. Nature 2004, 430, 153-155.
-
(2004)
Nature
, vol.430
, pp. 153-155
-
-
Garcia, M.L.1
-
97
-
-
29644442350
-
Lipid membrane interaction and antimicrobial activity of GsMTx-4, an inhibitor of mechanosensitive channel
-
Jung, H.J.; Kim, P.I.; Lee, S.K.; Lee, C.W.; Eu, Y.J.; Lee, D.G.; Earm, Y.E.; Kim, J.I. Lipid membrane interaction and antimicrobial activity of GsMTx-4, an inhibitor of mechanosensitive channel. Biochem. Biophys. Res. Commun. 2006, 340, 633-638.
-
(2006)
Biochem. Biophys. Res. Commun
, vol.340
, pp. 633-638
-
-
Jung, H.J.1
Kim, P.I.2
Lee, S.K.3
Lee, C.W.4
Eu, Y.J.5
Lee, D.G.6
Earm, Y.E.7
Kim, J.I.8
-
98
-
-
0028837352
-
Physiology of penile erection
-
Andersson, K.E.; Wagner, G. Physiology of penile erection. Physiol. Rev. 1995, 75, 191-236.
-
(1995)
Physiol. Rev
, vol.75
, pp. 191-236
-
-
Andersson, K.E.1
Wagner, G.2
-
99
-
-
18044372877
-
Nitric oxide and penile erectile function
-
Toda, N.; Ayajiki, K.; Okamura, T. Nitric oxide and penile erectile function. Pharmacol. Therapeut. 2005, 106, 233-266.
-
(2005)
Pharmacol. Therapeut
, vol.106
, pp. 233-266
-
-
Toda, N.1
Ayajiki, K.2
Okamura, T.3
-
100
-
-
77952829688
-
A new era in the treatment of erectile dysfunction: Chronic phosphodiesterase type 5 inhibition
-
Fusco, F.; Razzoli, E.; Imbimbo, C.; Rossi, A.; Verze, P.; Mirone, V. A new era in the treatment of erectile dysfunction: Chronic phosphodiesterase type 5 inhibition. BJU Int. 2010, 105, 1634-1639.
-
(2010)
BJU Int
, vol.105
, pp. 1634-1639
-
-
Fusco, F.1
Razzoli, E.2
Imbimbo, C.3
Rossi, A.4
Verze, P.5
Mirone, V.6
-
101
-
-
0033522244
-
Sildenafil citrate and blood-pressure-lowering drugs: Results of drug interaction studies with an organic nitrate and a calcium antagonist
-
Webb, D.J.; Freestone, S.; Allen, M.J.; Muirhead, G.J. Sildenafil citrate and blood-pressure-lowering drugs: Results of drug interaction studies with an organic nitrate and a calcium antagonist. Am. J. Cardiol. 1999, 83, 21-28.
-
(1999)
Am. J. Cardiol
, vol.83
, pp. 21-28
-
-
Webb, D.J.1
Freestone, S.2
Allen, M.J.3
Muirhead, G.J.4
-
102
-
-
33746154470
-
Comparison of phosphodiesterase type 5 (PDE5) inhibitors
-
Wright, P.J. Comparison of phosphodiesterase type 5 (PDE5) inhibitors. Int. J. Clin. Pract. 2006, 60, 967-975.
-
(2006)
Int. J. Clin. Pract
, vol.60
, pp. 967-975
-
-
Wright, P.J.1
-
103
-
-
0026705696
-
The purification and amino acid sequences of four Tx2 neurotoxins from the venom of the Brazilian 'armed' spider Phoneutria nigriventer (Keys)
-
Cordeiro, M.N.; Diniz, C.R.; Valentim, A.C.; von Eickstedt, V.R.D.; Gilroy, J.; Richardson, M. The purification and amino acid sequences of four Tx2 neurotoxins from the venom of the Brazilian 'armed' spider Phoneutria nigriventer (Keys). FEBS Lett. 1992, 310, 153-156.
-
(1992)
FEBS Lett
, vol.310
, pp. 153-156
-
-
Cordeiro, M.N.1
Diniz, C.R.2
Valentim, A.C.3
von Eickstedt, V.R.D.4
Gilroy, J.5
Richardson, M.6
-
104
-
-
65249116952
-
Structure and activity analysis of two spider toxins that alter sodium channel inactivation kinetics
-
Matavel, A.; Fleury, C.; Oliveira, L.C.; Molina, F.; de Lima, M.E.; Cruz, J.S.; Cordeiro, M.N.; Richardson, M.; Ramos, C.H.; Beirao, P.S. Structure and activity analysis of two spider toxins that alter sodium channel inactivation kinetics. Biochemistry 2009, 48, 3078-3088.
-
(2009)
Biochemistry
, vol.48
, pp. 3078-3088
-
-
Matavel, A.1
Fleury, C.2
Oliveira, L.C.3
Molina, F.4
de Lima, M.E.5
Cruz, J.S.6
Cordeiro, M.N.7
Richardson, M.8
Ramos, C.H.9
Beirao, P.S.10
-
105
-
-
43749109811
-
Tx2-6 toxin of the Phoneutria nigriventer spider potentiates rat erectile function
-
Nunes, K.P.; Costa-Goncalves, A.; Lanza, L.F.; Cortes, S.F.; Cordeiro, M.N.; Richardson, M.; Pimenta, A.M.; Webb, R.C.; Leite, R.; De Lima, M.E. Tx2-6 toxin of the Phoneutria nigriventer spider potentiates rat erectile function. Toxicon 2008, 51, 1197-1206.
-
(2008)
Toxicon
, vol.51
, pp. 1197-1206
-
-
Nunes, K.P.1
Costa-Goncalves, A.2
Lanza, L.F.3
Cortes, S.F.4
Cordeiro, M.N.5
Richardson, M.6
Pimenta, A.M.7
Webb, R.C.8
Leite, R.9
de Lima, M.E.10
-
106
-
-
50949130292
-
Penile erection induced in vivo by a purified toxin from the Brazilian spider Phoneutria nigriventer
-
Andrade, E.; Villanova, F.; Borra, P.; Leite, K.; Troncone, L.; Cortez, I.; Messina, L.; Paranhos, M.; Claro, J.; Srougi, M. Penile erection induced in vivo by a purified toxin from the Brazilian spider Phoneutria nigriventer. BJU Int. 2008, 102, 835-837.
-
(2008)
BJU Int
, vol.102
, pp. 835-837
-
-
Andrade, E.1
Villanova, F.2
Borra, P.3
Leite, K.4
Troncone, L.5
Cortez, I.6
Messina, L.7
Paranhos, M.8
Claro, J.9
Srougi, M.10
-
108
-
-
0038354946
-
Trends in mortality rates for infectious and parasitic diseases in Australia: 1907-1997
-
Bi, P.; Whitby, M.; Walker, S.; Parton, K.A. Trends in mortality rates for infectious and parasitic diseases in Australia: 1907-1997. Intern. Med. J. 2003, 33, 152-162.
-
(2003)
Intern. Med. J
, vol.33
, pp. 152-162
-
-
Bi, P.1
Whitby, M.2
Walker, S.3
Parton, K.A.4
-
109
-
-
26444491047
-
Resistance to antibiotics: Are we in the post-antibiotic era
-
Alanis, A.J. Resistance to antibiotics: Are we in the post-antibiotic era? Arch Med. Res. 2005, 36, 697-705.
-
(2005)
Arch Med. Res
, vol.36
, pp. 697-705
-
-
Alanis, A.J.1
-
110
-
-
77956261728
-
Daptomycin, a bacterial lipopeptide synthesized by a nonribosomal machinery
-
Robbel, L.; Marahiel, M.A. Daptomycin, a bacterial lipopeptide synthesized by a nonribosomal machinery. J. Biol. Chem. 2010, 285, 27501-27508.
-
(2010)
J. Biol. Chem
, vol.285
, pp. 27501-27508
-
-
Robbel, L.1
Marahiel, M.A.2
-
111
-
-
77955626468
-
Synthetic membrane-targeted antibiotics
-
Vooturi, S.K.; Firestine, S.M. Synthetic membrane-targeted antibiotics. Curr. Med. Chem. 2010, 17, 2292-2300.
-
(2010)
Curr. Med. Chem
, vol.17
, pp. 2292-2300
-
-
Vooturi, S.K.1
Firestine, S.M.2
-
112
-
-
0031941375
-
Lycotoxins, antimicrobial peptides from venom of the wolf spider Lycosa carolinensis
-
Yan, L.; Adams, M.E. Lycotoxins, antimicrobial peptides from venom of the wolf spider Lycosa carolinensis. J. Biol. Chem. 1998, 273, 2059-2066.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 2059-2066
-
-
Yan, L.1
Adams, M.E.2
-
113
-
-
0037192798
-
Cupiennin 1, a new family of highly basic antimicrobial peptides in the venom of the spider Cupiennius salei (Ctenidae)
-
Kuhn-Nentwig, L.; Muller, J.; Schaller, J.; Walz, A.; Dathe, M.; Nentwig, W. Cupiennin 1, a new family of highly basic antimicrobial peptides in the venom of the spider Cupiennius salei (Ctenidae). J. Biol. Chem. 2002, 277, 11208-11216.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 11208-11216
-
-
Kuhn-Nentwig, L.1
Muller, J.2
Schaller, J.3
Walz, A.4
Dathe, M.5
Nentwig, W.6
-
114
-
-
0037177839
-
Complete hemocyanin subunit sequences of the hunting spider Cupiennius salei: Recent hemocyanin remodeling in entelegyne spiders
-
Ballweber, P.; Markl, J.; Burmester, T. Complete hemocyanin subunit sequences of the hunting spider Cupiennius salei: Recent hemocyanin remodeling in entelegyne spiders. J. Biol. Chem. 2002, 277, 14451-14457.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 14451-14457
-
-
Ballweber, P.1
Markl, J.2
Burmester, T.3
-
115
-
-
0347991711
-
Antimicrobial and cytolytic peptides of venomous arthropods
-
Kuhn-Nentwig, L. Antimicrobial and cytolytic peptides of venomous arthropods. Cell. Mol. Life Sci. 2003, 60, 2651-2668.
-
(2003)
Cell. Mol. Life Sci
, vol.60
, pp. 2651-2668
-
-
Kuhn-Nentwig, L.1
-
116
-
-
33748920525
-
The effect of binding of spider-derived antimicrobial peptides, oxyopinins, on lipid membranes
-
Nomura, K.; Corzo, G. The effect of binding of spider-derived antimicrobial peptides, oxyopinins, on lipid membranes. Biochim. Biophys. Acta 2006, 1758, 1475-1482.
-
(2006)
Biochim. Biophys. Acta
, vol.1758
, pp. 1475-1482
-
-
Nomura, K.1
Corzo, G.2
-
117
-
-
33947380145
-
Solution structure and interaction of cupiennin 1a, a spider venom peptide, with phospholipid bilayers
-
Pukala, T.L.; Boland, M.P.; Gehman, J.D.; Kuhn-Nentwig, L.; Separovic, F.; Bowie, J.H. Solution structure and interaction of cupiennin 1a, a spider venom peptide, with phospholipid bilayers. Biochemistry 2007, 46, 3576-3585.
-
(2007)
Biochemistry
, vol.46
, pp. 3576-3585
-
-
Pukala, T.L.1
Boland, M.P.2
Gehman, J.D.3
Kuhn-Nentwig, L.4
Separovic, F.5
Bowie, J.H.6
-
118
-
-
40849106467
-
Three-dimensional structure/hydrophobicity of latarcins specifies their mode of membrane activity
-
3525-3233
-
Dubovskii, P.; Volynsky, P.E.; Polyansky, A.A.; Karpunin, D.V.; Chupin, V.V.; Efremov, R.G.; Arseniev, A.S. Three-dimensional structure/hydrophobicity of latarcins specifies their mode of membrane activity. Biochemistry 2008, 47, 3525-3233.
-
(2008)
Biochemistry
, vol.47
-
-
Dubovskii, P.1
Volynsky, P.E.2
Polyansky, A.A.3
Karpunin, D.V.4
Chupin, V.V.5
Efremov, R.G.6
Arseniev, A.S.7
-
120
-
-
0037189567
-
Oxyopinins, large amphipathic peptides isolated from the venom of the wolf spider Oxyopes kitabensis with cytolytic properties and positive insecticidal cooperativity with spider neurotoxins
-
Corzo, G.; Villegas, E.; Gomez-Lagunas, F.; Possani, L.D.; Belokoneva, O.S.; Nakajima, T. Oxyopinins, large amphipathic peptides isolated from the venom of the wolf spider Oxyopes kitabensis with cytolytic properties and positive insecticidal cooperativity with spider neurotoxins. J. Biol. Chem. 2002, 277, 23627-23637.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 23627-23637
-
-
Corzo, G.1
Villegas, E.2
Gomez-Lagunas, F.3
Possani, L.D.4
Belokoneva, O.S.5
Nakajima, T.6
-
121
-
-
1942534998
-
Biochemistry, toxicology and ecology of the venom of the spider Cupiennius salei (Ctenidae)
-
Kuhn-Nentwig, L.; Schaller, J.; Nentwig, W. Biochemistry, toxicology and ecology of the venom of the spider Cupiennius salei (Ctenidae). Toxicon 2004, 43, 543-553.
-
(2004)
Toxicon
, vol.43
, pp. 543-553
-
-
Kuhn-Nentwig, L.1
Schaller, J.2
Nentwig, W.3
-
122
-
-
42149140555
-
Membrane structure and interactions of a short Lycotoxin I analogue
-
Adão, R.; Seixas, R.; Gomes, P.; Pessoa, J.C.; Bastos, M. Membrane structure and interactions of a short Lycotoxin I analogue. J. Pept. Sci. 2008, 14, 528-534.
-
(2008)
J. Pept. Sci
, vol.14
, pp. 528-534
-
-
Adão, R.1
Seixas, R.2
Gomes, P.3
Pessoa, J.C.4
Bastos, M.5
-
123
-
-
73749087526
-
Cyclotides as templates in drug design
-
Henriques, S.T.; Craik, D.J. Cyclotides as templates in drug design. Drug Discov. Today 2010, 15, 57-64.
-
(2010)
Drug Discov. Today
, vol.15
, pp. 57-64
-
-
Henriques, S.T.1
Craik, D.J.2
-
124
-
-
77951957803
-
-
World Health Organization, WHO Press: Geneva, Switzerland
-
World Health Organization. World Malaria Report 2009; WHO Press: Geneva, Switzerland, 2009.
-
(2009)
World Malaria Report
, vol.2009
-
-
-
125
-
-
77449118596
-
Malaria management: Past, present, and future
-
Enayati, A.; Hemingway, J. Malaria management: past, present, and future. Annu. Rev. Entomol. 2010, 55, 569-591.
-
(2010)
Annu. Rev. Entomol
, vol.55
, pp. 569-591
-
-
Enayati, A.1
Hemingway, J.2
-
126
-
-
12744253952
-
The new permeability pathways: Targets and selective routes for the development of new antimalarial agents
-
Staines, H.M.; Ellory, J.C.; Chibale, K. The new permeability pathways: targets and selective routes for the development of new antimalarial agents. Comb. Chem. High Throughput Screen 2005, 8, 81-88.
-
(2005)
Comb. Chem. High Throughput Screen
, vol.8
, pp. 81-88
-
-
Staines, H.M.1
Ellory, J.C.2
Chibale, K.3
-
127
-
-
0036378336
-
Spiders of medical importance in the Asia-Pacific: Atracotoxin, latrotoxin and related spider neurotoxins
-
Nicholson, G.M.; Graudins, A. Spiders of medical importance in the Asia-Pacific: atracotoxin, latrotoxin and related spider neurotoxins. Clin. Exp. Pharmacol. Physiol. 2002, 29, 785-794.
-
(2002)
Clin. Exp. Pharmacol. Physiol
, vol.29
, pp. 785-794
-
-
Nicholson, G.M.1
Graudins, A.2
-
128
-
-
34548643963
-
Chemical modification of conotoxins to improve stability and activity
-
Craik, D.J.; Adams, D.J. Chemical modification of conotoxins to improve stability and activity. ACS Chem. Biol. 2007, 2, 457-468.
-
(2007)
ACS Chem. Biol
, vol.2
, pp. 457-468
-
-
Craik, D.J.1
Adams, D.J.2
-
129
-
-
74149094591
-
Synthetic therapeutic peptides: Science and market
-
Vlieghe, P.; Lisowski, V.; Martinez, J.; Khrestchatisky, M. Synthetic therapeutic peptides: science and market. Drug Discov. Today 2010, 15, 40-56.
-
(2010)
Drug Discov. Today
, vol.15
, pp. 40-56
-
-
Vlieghe, P.1
Lisowski, V.2
Martinez, J.3
Khrestchatisky, M.4
-
130
-
-
0023683508
-
Relationship of effective molecular-size to systemic clearance in rats of recombinant interleukin-2 chemically modified with water-soluble polymers
-
Knauf, M.J.; Bell, D.P.; Hirtzer, P.; Luo, Z.P.; Young, J.D.; Katre, N.V. Relationship of effective molecular-size to systemic clearance in rats of recombinant interleukin-2 chemically modified with water-soluble polymers. J. Biol. Chem. 1988, 263, 15064-15070.
-
(1988)
J. Biol. Chem
, vol.263
, pp. 15064-15070
-
-
Knauf, M.J.1
Bell, D.P.2
Hirtzer, P.3
Luo, Z.P.4
Young, J.D.5
Katre, N.V.6
-
131
-
-
0032404493
-
The development of site-specific drug-delivery systems for protein and peptide biopharmaceuticals
-
Pettit, D.K.; Gombotz, W.R. The development of site-specific drug-delivery systems for protein and peptide biopharmaceuticals. Trends Biotechnol. 1998, 16, 343-349.
-
(1998)
Trends Biotechnol
, vol.16
, pp. 343-349
-
-
Pettit, D.K.1
Gombotz, W.R.2
-
132
-
-
0035854663
-
Functional significance of the β-hairpin in the insecticidal neurotoxin ω-atracotoxin-Hv1a
-
Tedford, H.W.; Fletcher, J.I.; King, G.F. Functional significance of the β-hairpin in the insecticidal neurotoxin ω-atracotoxin-Hv1a. J. Biol. Chem. 2001, 276, 26568-26576.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 26568-26576
-
-
Tedford, H.W.1
Fletcher, J.I.2
King, G.F.3
-
133
-
-
6344287807
-
Scanning mutagenesis of ω-atracotoxin-Hv1a reveals a spatially restricted epitope that confers selective activity against invertebrate calcium channels
-
Tedford, H.W.; Gilles, N.; Ménez, A.; Doering, C.J.; Zamponi, G.W.; King, G.F. Scanning mutagenesis of ω-atracotoxin-Hv1a reveals a spatially restricted epitope that confers selective activity against invertebrate calcium channels. J. Biol. Chem. 2004, 279, 44133-44140.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 44133-44140
-
-
Tedford, H.W.1
Gilles, N.2
Ménez, A.3
Doering, C.J.4
Zamponi, G.W.5
King, G.F.6
-
134
-
-
0037212039
-
Small molecule antagonists of proteins
-
Gadek, T.R.; Nicholas, J.B. Small molecule antagonists of proteins. Biochem. Pharmacol. 2003, 65, 1-8.
-
(2003)
Biochem. Pharmacol
, vol.65
, pp. 1-8
-
-
Gadek, T.R.1
Nicholas, J.B.2
-
135
-
-
1842477970
-
ω-Conotoxins and approaches to their nonpeptide mimetics
-
Baell, J.B.; Duggan, P.J.; Lok, Y.P. ω-Conotoxins and approaches to their nonpeptide mimetics. Aust. J. Chem. 2004, 57, 179-185.
-
(2004)
Aust. J. Chem
, vol.57
, pp. 179-185
-
-
Baell, J.B.1
Duggan, P.J.2
Lok, Y.P.3
-
136
-
-
20444411881
-
A three-residue, continuous binding epitope peptidomimetic of ShK toxin as a Kv1.3 inhibitor
-
Harvey, A.J.; Gable, R.W.; Baell, J.B. A three-residue, continuous binding epitope peptidomimetic of ShK toxin as a Kv1.3 inhibitor. Bioorg. Med. Chem. Lett. 2005, 15, 3193-3196.
-
(2005)
Bioorg. Med. Chem. Lett
, vol.15
, pp. 3193-3196
-
-
Harvey, A.J.1
Gable, R.W.2
Baell, J.B.3
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