-
1
-
-
22844436446
-
P2X receptors: Targets for novel analgesics?
-
Kennedy C. P2X receptors: targets for novel analgesics? Neuroscientist 2005;11:345-356.
-
(2005)
Neuroscientist
, vol.11
, pp. 345-356
-
-
Kennedy, C.1
-
2
-
-
33746701380
-
P2X receptors as cell-surface ATP sensors in health and disease
-
Khakh BS, North RA. P2X receptors as cell-surface ATP sensors in health and disease. Nature 2006;442:527-532.
-
(2006)
Nature
, vol.442
, pp. 527-532
-
-
Khakh, B.S.1
North, R.A.2
-
4
-
-
0036788971
-
Molecular physiology of P2X receptors
-
North RA. Molecular physiology of P2X receptors. Physiol Rev 2002;82:1013-1067.
-
(2002)
Physiol Rev
, vol.82
, pp. 1013-1067
-
-
North, R.A.1
-
5
-
-
67949117176
-
Crystal structure of the ATP-gated P2X(4) ion channel in the closed state
-
Kawate T, Michel JC, Birdsong WT, et al. Crystal structure of the ATP-gated P2X(4) ion channel in the closed state. Nature 2009;460:592-598.
-
(2009)
Nature
, Issue.460
, pp. 592-598
-
-
Kawate, T.1
Michel, J.C.2
Birdsong, W.T.3
-
6
-
-
0037168683
-
2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat
-
DOI 10.1073/pnas.252537299
-
Jarvis MF, Burgard EC, McGaraughty S, et al. A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat. Proc Natl Acad Sci U S A 2002;99:17179-17184. (Pubitemid 36034118)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.26
, pp. 17179-17184
-
-
Jarvis, M.F.1
Burgard, E.C.2
McGaraughty, S.3
Honore, P.4
Lynch, K.5
Brennan, T.J.6
Subieta, A.7
Van Biesen, T.8
Cartmell, J.9
Bianchi, B.10
Niforatos, W.11
Kage, K.12
Yu, H.13
Mikusa, J.14
Wismer, C.T.15
Zhu, C.Z.16
Chu, K.17
Lee, C.-H.18
Stewart, A.O.19
Polakowski, J.20
Cox, B.F.21
Kowaluk, E.22
Williams, M.23
Sullivan, J.24
Faltynek, C.25
more..
-
7
-
-
33745146902
-
The suramin analog 4,4′,4″,4‴-(carbonylbis(imino-5,1, 3-benzenetriylbis (carbonylimino)))tetra-kis-benzenesulfonic acid (NF110) potently blocks P2X3 receptors: Subtype selectivity is determined by location of sulfonic acid groups
-
Hausmann R, Rettinger J, Gerevich Z, et al. The suramin analog 4,4′,4″,4‴-(carbonylbis(imino-5,1,3-benzenetriylbis (carbonylimino)))tetra-kis-benzenesulfonic acid (NF110) potently blocks P2X3 receptors: subtype selectivity is determined by location of sulfonic acid groups. Mol Pharmacol 2006;69:2058-2067.
-
(2006)
Mol Pharmacol
, vol.69
, pp. 2058-2067
-
-
Hausmann, R.1
Rettinger, J.2
Gerevich, Z.3
-
8
-
-
34548494816
-
Structure-activity relationship studies of spinorphin as a potent and selective human P2X(3) receptor antagonist
-
Jung KY, Moon HD, Lee GE, et al. Structure-activity relationship studies of spinorphin as a potent and selective human P2X(3) receptor antagonist. J Med Chem 2007;50:4543-4547.
-
(2007)
J Med Chem
, vol.50
, pp. 4543-4547
-
-
Jung, K.Y.1
Moon, H.D.2
Lee, G.E.3
-
9
-
-
0242331757
-
Therapeutic potential of venom peptides
-
Lewis RJ, Garcia ML. Therapeutic potential of venom peptides. Nat Rev Drug Discov 2003;2:790-802.
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 790-802
-
-
Lewis, R.J.1
Garcia, M.L.2
-
10
-
-
0029102288
-
A P2X purinoceptor expressed by a subset of sensory neurons
-
Chen CC, Akopian AN, Sivilotti L, et al. A P2X purinoceptor expressed by a subset of sensory neurons. Nature 1995;377:428-431.
-
(1995)
Nature
, vol.377
, pp. 428-431
-
-
Chen, C.C.1
Akopian, A.N.2
Sivilotti, L.3
-
11
-
-
0023924046
-
A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
-
Hargreaves K, Dubner R, Brown F, et al. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 1988;32:77-88.
-
(1988)
Pain
, vol.32
, pp. 77-88
-
-
Hargreaves, K.1
Dubner, R.2
Brown, F.3
-
12
-
-
1642464613
-
Diversity of folds in animal toxins acting on ion channels
-
DOI 10.1042/BJ20031860
-
Mouhat S, Jouirou B, Mosbah A, et al. Diversity of folds in animal toxins acting on ion channels. Biochem J 2004;378:717-726. (Pubitemid 38406846)
-
(2004)
Biochemical Journal
, vol.378
, Issue.3
, pp. 717-726
-
-
Mouhat, S.1
Jouirou, B.2
Mosbah, A.3
De Waard, M.4
Sabatier, J.-M.5
-
13
-
-
23744515639
-
3 receptors by nanomolar agonist
-
DOI 10.1523/JNEUROSCI.5189-04.2005
-
Pratt EB, Brink TS, Bergson P, et al. Use-dependent inhibition of P2X3 receptors by nanomolar agonist. J Neurosci 2005;25:7359-7365. (Pubitemid 41129808)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.32
, pp. 7359-7365
-
-
Pratt, E.B.1
Brink, T.S.2
Bergson, P.3
Voigt, M.M.4
Cook, S.P.5
-
14
-
-
0036139259
-
Peripheral inflammation sensitizes P2X receptor-mediated responses in rat dorsal root ganglion neurons
-
Xu GY, Huang LY. Peripheral inflammation sensitizes P2X receptor-mediated responses in rat dorsal root ganglion neurons. J Neurosci 2002;22:93-102. (Pubitemid 34033487)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.1
, pp. 93-102
-
-
Xu, G.-Y.1
Huang, L.-Y.M.2
-
15
-
-
0034682749
-
+ channels
-
Escoubas P, De Weille JR, Lecoq A, et al. Isolation of a tarantula toxin specific for a class of proton-gated Na+ channels. J Biol Chem 2000;275:25116-25121. (Pubitemid 30658753)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.33
-
-
Escoubas, P.1
De Weille, J.R.2
Lecoq, A.3
Diochot, S.4
Waldmann, R.5
Champigny, G.6
Moinier, D.7
Menez, A.8
Lazdunski, M.9
-
16
-
-
2342629343
-
A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons
-
DOI 10.1038/sj.emboj.7600177
-
Diochot S, Baron A, Rash LD, et al. A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons. EMBO J 2004;23:1516-1525. (Pubitemid 38579512)
-
(2004)
EMBO Journal
, vol.23
, Issue.7
, pp. 1516-1525
-
-
Diochot, S.1
Baron, A.2
Rash, L.D.3
Deval, E.4
Escoubas, P.5
Scarzello, S.6
Salinas, M.7
Lazdunski, M.8
-
17
-
-
33750873334
-
Spider toxins activate the capsaicin receptor to produce inflammatory pain
-
DOI 10.1038/nature05285, PII NATURE05285
-
Siemens J, Zhou S, Piskorowski R, et al. Spider toxins activate the capsaicin receptor to produce inflammatory pain. Nature 2006;444:208-212. (Pubitemid 44722061)
-
(2006)
Nature
, vol.444
, Issue.7116
, pp. 208-212
-
-
Siemens, J.1
Zhou, S.2
Piskorowski, R.3
Nikai, T.4
Lumpkin, E.A.5
Basbaum, A.I.6
King, D.7
Julius, D.8
-
18
-
-
53049093899
-
Analgesic compound from sea anemone Heteractis crispa is the first polypeptide inhibitor of vanilloid receptor 1 (TRPV1)
-
Andreev YA, Kozlov SA, Koshelev SG, et al. Analgesic compound from sea anemone Heteractis crispa is the first polypeptide inhibitor of vanilloid receptor 1 (TRPV1). J Biol Chem 2008;283:23914-23921.
-
(2008)
J Biol Chem
, vol.283
, pp. 23914-23921
-
-
Andreev, Y.A.1
Kozlov, S.A.2
Koshelev, S.G.3
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