Acid-sensing ion channels (ASICs) as pharmacological targets for neurodegenerative diseases

Current Opinion in Pharmacology

Volumn 8, Issue 1, 2008, Pages 25-32

  Xiong, Zhi Gang ^a   Pignataro, Giuseppe ^b   Li, Minghua ^a   Chang, Su youne ^a   Simon, Roger P ^a  

^a LEGACY RESEARCH   (United States)

^b University School of Medicine Federico II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

A 317567; ACETYLSALICYLIC ACID; ACID SENSING ION CHANNEL; AMILORIDE; CALCIUM ION; CATION CHANNEL; DICLOFENAC; FLURBIPROFEN; IBUPROFEN; ION TRANSPORT AFFECTING AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE; PROTON; PSALMOTOXIN 1; SALICYLIC ACID; SEA ANEMONE TOXIN; SODIUM CALCIUM EXCHANGE PROTEIN; SODIUM ION; UNCLASSIFIED DRUG;

ACIDOSIS; ANALGESIA; ANTIINFLAMMATORY ACTIVITY; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CELL MEMBRANE PERMEABILITY; CENTRAL NERVOUS SYSTEM; CEREBROVASCULAR ACCIDENT; CHANNEL GATING; DEGENERATIVE DISEASE; DIURESIS; DRUG STRUCTURE; DRUG TARGETING; ENZYME INHIBITION; HUMAN; INHIBITION KINETICS; NATRIURESIS; NERVE CELL; NERVE CELL PLASTICITY; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NEUROLOGIC DISEASE; NEUROPROTECTION; NOCICEPTION; NONHUMAN; PAIN; PH; POSTOPERATIVE PAIN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS INHIBITION; PROTEIN EXPRESSION; REVIEW; SEIZURE; SENSORY NERVE CELL; SKIN INCISION; TISSUE DISTRIBUTION; TRAUMATIC BRAIN INJURY;

AMILORIDE; ANIMALS; BRAIN ISCHEMIA; CALCIUM; EPILEPSY; HUMANS; HYDROGEN-ION CONCENTRATION; MEMBRANE PROTEINS; NERVE TISSUE PROTEINS; NEURODEGENERATIVE DISEASES; NEURONS; SODIUM CHANNELS;

EID: 38649129918     PISSN: 14714892     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.coph.2007.09.001     Document Type: Review

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