-
1
-
-
33847050801
-
Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway
-
Kensler T.W., Wakabayashi N., Biswal S. Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annu Rev Pharmacol Toxicol 2007, 47:89-116.
-
(2007)
Annu Rev Pharmacol Toxicol
, vol.47
, pp. 89-116
-
-
Kensler, T.W.1
Wakabayashi, N.2
Biswal, S.3
-
2
-
-
74049120454
-
Nrf2: friend or foe for chemoprevention?
-
Kensler T.W., Wakabayashi N. Nrf2: friend or foe for chemoprevention?. Carcinogenesis 2010, 31:90-99.
-
(2010)
Carcinogenesis
, vol.31
, pp. 90-99
-
-
Kensler, T.W.1
Wakabayashi, N.2
-
3
-
-
33750613056
-
Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism
-
Tong K.I., Kobayashi A., Katsuoka F., Yamamoto M. Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism. Biol Chem 2006, 387:1311-1320.
-
(2006)
Biol Chem
, vol.387
, pp. 1311-1320
-
-
Tong, K.I.1
Kobayashi, A.2
Katsuoka, F.3
Yamamoto, M.4
-
4
-
-
33748052967
-
Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species
-
Kobayashi M., Yamamoto M. Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species. Adv Enzyme Regul 2006, 46:113-140.
-
(2006)
Adv Enzyme Regul
, vol.46
, pp. 113-140
-
-
Kobayashi, M.1
Yamamoto, M.2
-
5
-
-
0037015035
-
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
-
Dinkova-Kostova A.T., Holtzclaw W.D., Cole R.N., Itoh K., Wakabayashi N., Katoh Y., Yamamoto M., Talalay P. Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants. Proc Natl Acad Sci U S A 2002, 99:11908-11913.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 11908-11913
-
-
Dinkova-Kostova, A.T.1
Holtzclaw, W.D.2
Cole, R.N.3
Itoh, K.4
Wakabayashi, N.5
Katoh, Y.6
Yamamoto, M.7
Talalay, P.8
-
6
-
-
0242580049
-
Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress
-
Zhang D.D., Hannink M. Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress. Mol Cell Biol 2003, 23:8137-8151.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 8137-8151
-
-
Zhang, D.D.1
Hannink, M.2
-
7
-
-
42149196050
-
Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity
-
Yamamoto T., Suzuki T., Kobayashi A., Wakabayashi J., Maher J., Motohashi H., Yamamoto M. Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity. Mol Cell Biol 2008, 28:2758-2770.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 2758-2770
-
-
Yamamoto, T.1
Suzuki, T.2
Kobayashi, A.3
Wakabayashi, J.4
Maher, J.5
Motohashi, H.6
Yamamoto, M.7
-
8
-
-
18244377997
-
Keap1, the sensor for electrophiles and oxidants that regulates the phase 2 response, is a zinc metalloprotein
-
Dinkova-Kostova A.T., Holtzclaw W.D., Wakabayashi N. Keap1, the sensor for electrophiles and oxidants that regulates the phase 2 response, is a zinc metalloprotein. Biochemistry 2005, 44:6889-6899.
-
(2005)
Biochemistry
, vol.44
, pp. 6889-6899
-
-
Dinkova-Kostova, A.T.1
Holtzclaw, W.D.2
Wakabayashi, N.3
-
9
-
-
41849146057
-
Covalent modification at Cys151 dissociates the electrophile sensor Keap1 from the ubiquitin ligase CUL3
-
Rachakonda G., Xiong Y., Sekhar K.R., Stamer S.L., Liebler D.C., Freeman M.L. Covalent modification at Cys151 dissociates the electrophile sensor Keap1 from the ubiquitin ligase CUL3. Chem Res Toxicol 2008, 21:705-710.
-
(2008)
Chem Res Toxicol
, vol.21
, pp. 705-710
-
-
Rachakonda, G.1
Xiong, Y.2
Sekhar, K.R.3
Stamer, S.L.4
Liebler, D.C.5
Freeman, M.L.6
-
10
-
-
78650509515
-
Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals
-
McMahon M., Lamont D.J., Beattie K.A., Hayes J.D. Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals. Proc Natl Acad Sci U S A 2010, 107:18838-18843.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 18838-18843
-
-
McMahon, M.1
Lamont, D.J.2
Beattie, K.A.3
Hayes, J.D.4
-
11
-
-
46749152185
-
Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1-Cul3 interaction
-
Wang X.J., Sun Z., Chen W., Li Y., Villeneuve N.F., Zhang D.D. Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1-Cul3 interaction. Toxicol Appl Pharmacol 2008, 230:383-389.
-
(2008)
Toxicol Appl Pharmacol
, vol.230
, pp. 383-389
-
-
Wang, X.J.1
Sun, Z.2
Chen, W.3
Li, Y.4
Villeneuve, N.F.5
Zhang, D.D.6
-
12
-
-
1542335553
-
Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol
-
Martin D., Rojo A.I., Salinas M., Diaz R., Gallardo G., Alam J., De Galarreta C.M., Cuadrado A. Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol. J Biol Chem 2004, 279:8919-8929.
-
(2004)
J Biol Chem
, vol.279
, pp. 8919-8929
-
-
Martin, D.1
Rojo, A.I.2
Salinas, M.3
Diaz, R.4
Gallardo, G.5
Alam, J.6
De Galarreta, C.M.7
Cuadrado, A.8
-
13
-
-
20344382953
-
Quercetin, but not rutin and quercitrin, prevention of H2O2-induced apoptosis via anti-oxidant activity and heme oxygenase 1 gene expression in macrophages
-
Chow J.M., Shen S.C., Huan S.K., Lin H.Y., Chen Y.C. Quercetin, but not rutin and quercitrin, prevention of H2O2-induced apoptosis via anti-oxidant activity and heme oxygenase 1 gene expression in macrophages. Biochem Pharmacol 2005, 69:1839-1851.
-
(2005)
Biochem Pharmacol
, vol.69
, pp. 1839-1851
-
-
Chow, J.M.1
Shen, S.C.2
Huan, S.K.3
Lin, H.Y.4
Chen, Y.C.5
-
14
-
-
0035827505
-
Phosphatidylinositol 3-kinase, not extracellular signal-regulated kinase, regulates activation of the antioxidant-responsive element in IMR-32 human neuroblastoma cells
-
Lee J.M., Hanson J.M., Chu W.A., Johnson J.A. Phosphatidylinositol 3-kinase, not extracellular signal-regulated kinase, regulates activation of the antioxidant-responsive element in IMR-32 human neuroblastoma cells. J Biol Chem 2001, 276:20011-20016.
-
(2001)
J Biol Chem
, vol.276
, pp. 20011-20016
-
-
Lee, J.M.1
Hanson, J.M.2
Chu, W.A.3
Johnson, J.A.4
-
15
-
-
77649270763
-
Targeting NRF2 signaling for cancer chemoprevention
-
Kwak M.K., Kensler T.W. Targeting NRF2 signaling for cancer chemoprevention. Toxicol Appl Pharmacol 2010, 244:66-76.
-
(2010)
Toxicol Appl Pharmacol
, vol.244
, pp. 66-76
-
-
Kwak, M.K.1
Kensler, T.W.2
-
17
-
-
77953228968
-
Nrf2-Keap1 signaling as a potential target for chemoprevention of inflammation-associated carcinogenesis
-
Kundu J.K., Surh Y.J. Nrf2-Keap1 signaling as a potential target for chemoprevention of inflammation-associated carcinogenesis. Pharm Res 2010, 27:999-1013.
-
(2010)
Pharm Res
, vol.27
, pp. 999-1013
-
-
Kundu, J.K.1
Surh, Y.J.2
-
18
-
-
0015334747
-
Inhibition of carcinogenic and toxic effects of polycyclic hydrocarbons by phenolic antioxidants and ethoxyquin
-
Wattenberg L.W. Inhibition of carcinogenic and toxic effects of polycyclic hydrocarbons by phenolic antioxidants and ethoxyquin. J Natl Cancer Inst 1972, 48:1425-1430.
-
(1972)
J Natl Cancer Inst
, vol.48
, pp. 1425-1430
-
-
Wattenberg, L.W.1
-
19
-
-
0024997241
-
Transcriptional regulation of the rat glutathione S-transferase Ya subunit gene. Characterization of a xenobiotic-responsive element controlling inducible expression by phenolic antioxidants
-
Rushmore T.H., Pickett C.B. Transcriptional regulation of the rat glutathione S-transferase Ya subunit gene. Characterization of a xenobiotic-responsive element controlling inducible expression by phenolic antioxidants. J Biol Chem 1990, 265:14648-14653.
-
(1990)
J Biol Chem
, vol.265
, pp. 14648-14653
-
-
Rushmore, T.H.1
Pickett, C.B.2
-
20
-
-
75449091854
-
Activation of the NRF2 signaling pathway by copper-mediated redox cycling of para- and ortho-hydroquinones
-
Wang X.J., Hayes J.D., Higgins L.G., Wolf C.R., Dinkova-Kostova A.T. Activation of the NRF2 signaling pathway by copper-mediated redox cycling of para- and ortho-hydroquinones. Chem Biol 2010, 17:75-85.
-
(2010)
Chem Biol
, vol.17
, pp. 75-85
-
-
Wang, X.J.1
Hayes, J.D.2
Higgins, L.G.3
Wolf, C.R.4
Dinkova-Kostova, A.T.5
-
21
-
-
34147165621
-
Curcumin induces heme oxygenase 1 through generation of reactive oxygen species, p38 activation and phosphatase inhibition
-
McNally S.J., Harrison E.M., Ross J.A., Garden O.J., Wigmore S.J. Curcumin induces heme oxygenase 1 through generation of reactive oxygen species, p38 activation and phosphatase inhibition. Int J Mol Med 2007, 19:165-172.
-
(2007)
Int J Mol Med
, vol.19
, pp. 165-172
-
-
McNally, S.J.1
Harrison, E.M.2
Ross, J.A.3
Garden, O.J.4
Wigmore, S.J.5
-
22
-
-
39149106003
-
Curcumin attenuates dimethylnitrosamine-induced liver injury in rats through Nrf2-mediated induction of heme oxygenase-1
-
Farombi E.O., Shrotriya S., Na H.K., Kim S.H., Surh Y.J. Curcumin attenuates dimethylnitrosamine-induced liver injury in rats through Nrf2-mediated induction of heme oxygenase-1. Food Chem Toxicol 2008, 46:1279-1287.
-
(2008)
Food Chem Toxicol
, vol.46
, pp. 1279-1287
-
-
Farombi, E.O.1
Shrotriya, S.2
Na, H.K.3
Kim, S.H.4
Surh, Y.J.5
-
23
-
-
46949104416
-
Dietary curcumin modulates transcriptional regulators of phase I and phase II enzymes in benzo[a]pyrene-treated mice: mechanism of its anti-initiating action
-
Garg R., Gupta S., Maru G.B. Dietary curcumin modulates transcriptional regulators of phase I and phase II enzymes in benzo[a]pyrene-treated mice: mechanism of its anti-initiating action. Carcinogenesis 2008, 29:1022-1032.
-
(2008)
Carcinogenesis
, vol.29
, pp. 1022-1032
-
-
Garg, R.1
Gupta, S.2
Maru, G.B.3
-
24
-
-
61549133952
-
Curcumin attenuates oxidative damage in animals treated with a renal carcinogen, ferric nitrilotriacetate (Fe-NTA): implications for cancer prevention
-
Iqbal M., Okazaki Y., Okada S. Curcumin attenuates oxidative damage in animals treated with a renal carcinogen, ferric nitrilotriacetate (Fe-NTA): implications for cancer prevention. Mol Cell Biochem 2009, 324:157-164.
-
(2009)
Mol Cell Biochem
, vol.324
, pp. 157-164
-
-
Iqbal, M.1
Okazaki, Y.2
Okada, S.3
-
25
-
-
58849102674
-
Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator
-
Jiao Y., Wilkinson J.t., Di X., Wang W., Hatcher H., Kock N.D., D'Agostino R., Knovich M.A., Torti F.M., Torti S.V. Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator. Blood 2009, 113:462-469.
-
(2009)
Blood
, vol.113
, pp. 462-469
-
-
Jiao, Y.1
Wilkinson, J.2
Di, X.3
Wang, W.4
Hatcher, H.5
Kock, N.D.6
D'Agostino, R.7
Knovich, M.A.8
Torti, F.M.9
Torti, S.V.10
-
26
-
-
68349148206
-
Potential protection of curcumin against amyloid beta-induced toxicity on cultured rat prefrontal cortical neurons
-
Qin X.Y., Cheng Y., Cui J., Zhang Y., Yu L.C. Potential protection of curcumin against amyloid beta-induced toxicity on cultured rat prefrontal cortical neurons. Neurosci Lett 2009, 463:158-161.
-
(2009)
Neurosci Lett
, vol.463
, pp. 158-161
-
-
Qin, X.Y.1
Cheng, Y.2
Cui, J.3
Zhang, Y.4
Yu, L.C.5
-
27
-
-
44749093175
-
Curcumin: from ancient medicine to current clinical trials
-
Hatcher H., Planalp R., Cho J., Torti F.M., Torti S.V. Curcumin: from ancient medicine to current clinical trials. Cell Mol Life Sci 2008, 65:1631-1652.
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 1631-1652
-
-
Hatcher, H.1
Planalp, R.2
Cho, J.3
Torti, F.M.4
Torti, S.V.5
-
28
-
-
0035503597
-
The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse
-
Lim G.P., Chu T., Yang F., Beech W., Frautschy S.A., Cole G.M. The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J Neurosci 2001, 21:8370-8377.
-
(2001)
J Neurosci
, vol.21
, pp. 8370-8377
-
-
Lim, G.P.1
Chu, T.2
Yang, F.3
Beech, W.4
Frautschy, S.A.5
Cole, G.M.6
-
29
-
-
79851512240
-
Coffee, broccoli and spices are strong inducers of electrophile response element-dependent transcription in vitro and in vivo-studies in electrophile response element transgenic mice
-
Balstad T.R., Carlsen H., Myhrstad M.C., Kolberg M., Reiersen H., Gilen L., Ebihara K., Paur I., Blomhoff R. Coffee, broccoli and spices are strong inducers of electrophile response element-dependent transcription in vitro and in vivo-studies in electrophile response element transgenic mice. Mol Nutr Food Res 2010, 54:1-13.
-
(2010)
Mol Nutr Food Res
, vol.54
, pp. 1-13
-
-
Balstad, T.R.1
Carlsen, H.2
Myhrstad, M.C.3
Kolberg, M.4
Reiersen, H.5
Gilen, L.6
Ebihara, K.7
Paur, I.8
Blomhoff, R.9
-
30
-
-
64049103791
-
Carnosic acid and carnosol inhibit adipocyte differentiation in mouse 3T3-L1 cells through induction of phase2 enzymes and activation of glutathione metabolism
-
Takahashi T., Tabuchi T., Tamaki Y., Kosaka K., Takikawa Y., Satoh T. Carnosic acid and carnosol inhibit adipocyte differentiation in mouse 3T3-L1 cells through induction of phase2 enzymes and activation of glutathione metabolism. Biochem Biophys Res Commun 2009, 382:549-554.
-
(2009)
Biochem Biophys Res Commun
, vol.382
, pp. 549-554
-
-
Takahashi, T.1
Tabuchi, T.2
Tamaki, Y.3
Kosaka, K.4
Takikawa, Y.5
Satoh, T.6
-
31
-
-
38449111059
-
Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1
-
Satoh T., Kosaka K., Itoh K., Kobayashi A., Yamamoto M., Shimojo Y., Kitajima C., Cui J., Kamins J., Okamoto S., et al. Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1. J Neurochem 2008, 104:1116-1131.
-
(2008)
J Neurochem
, vol.104
, pp. 1116-1131
-
-
Satoh, T.1
Kosaka, K.2
Itoh, K.3
Kobayashi, A.4
Yamamoto, M.5
Shimojo, Y.6
Kitajima, C.7
Cui, J.8
Kamins, J.9
Okamoto, S.10
-
32
-
-
40849145272
-
Carnosic acid protects neuronal HT22 Cells through activation of the antioxidant-responsive element in free carboxylic acid- and catechol hydroxyl moieties-dependent manners
-
Satoh T., Izumi M., Inukai Y., Tsutsumi Y., Nakayama N., Kosaka K., Shimojo Y., Kitajima C., Itoh K., Yokoi T., et al. Carnosic acid protects neuronal HT22 Cells through activation of the antioxidant-responsive element in free carboxylic acid- and catechol hydroxyl moieties-dependent manners. Neurosci Lett 2008, 434:260-265.
-
(2008)
Neurosci Lett
, vol.434
, pp. 260-265
-
-
Satoh, T.1
Izumi, M.2
Inukai, Y.3
Tsutsumi, Y.4
Nakayama, N.5
Kosaka, K.6
Shimojo, Y.7
Kitajima, C.8
Itoh, K.9
Yokoi, T.10
-
33
-
-
34247282872
-
Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin
-
Tanigawa S., Fujii M., Hou D.X. Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin. Free Radic Biol Med 2007, 42:1690-1703.
-
(2007)
Free Radic Biol Med
, vol.42
, pp. 1690-1703
-
-
Tanigawa, S.1
Fujii, M.2
Hou, D.X.3
-
34
-
-
38849134933
-
Raf and MEK protein kinases are direct molecular targets for the chemopreventive effect of quercetin, a major flavonol in red wine
-
Lee K.W., Kang N.J., Heo Y.S., Rogozin E.A., Pugliese A., Hwang M.K., Bowden G.T., Bode A.M., Lee H.J., Dong Z. Raf and MEK protein kinases are direct molecular targets for the chemopreventive effect of quercetin, a major flavonol in red wine. Cancer Res 2008, 68:946-955.
-
(2008)
Cancer Res
, vol.68
, pp. 946-955
-
-
Lee, K.W.1
Kang, N.J.2
Heo, Y.S.3
Rogozin, E.A.4
Pugliese, A.5
Hwang, M.K.6
Bowden, G.T.7
Bode, A.M.8
Lee, H.J.9
Dong, Z.10
-
35
-
-
33751116839
-
Quercetin, but not its glycosidated conjugate rutin, inhibits azoxymethane-induced colorectal carcinogenesis in F344 rats
-
Dihal A.A., de Boer V.C., van der Woude H., Tilburgs C., Bruijntjes J.P., Alink G.M., Rietjens I.M., Woutersen R.A., Stierum R.H. Quercetin, but not its glycosidated conjugate rutin, inhibits azoxymethane-induced colorectal carcinogenesis in F344 rats. J Nutr 2006, 136:2862-2867.
-
(2006)
J Nutr
, vol.136
, pp. 2862-2867
-
-
Dihal, A.A.1
de Boer, V.C.2
van der Woude, H.3
Tilburgs, C.4
Bruijntjes, J.P.5
Alink, G.M.6
Rietjens, I.M.7
Woutersen, R.A.8
Stierum, R.H.9
-
36
-
-
48749085399
-
Resveratrol protects primary rat hepatocytes against oxidative stress damage: activation of the Nrf2 transcription factor and augmented activities of antioxidant enzymes
-
Rubiolo J.A., Mithieux G., Vega F.V. Resveratrol protects primary rat hepatocytes against oxidative stress damage: activation of the Nrf2 transcription factor and augmented activities of antioxidant enzymes. Eur J Pharmacol 2008, 591:66-72.
-
(2008)
Eur J Pharmacol
, vol.591
, pp. 66-72
-
-
Rubiolo, J.A.1
Mithieux, G.2
Vega, F.V.3
-
37
-
-
41549108838
-
Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells
-
Kode A., Rajendrasozhan S., Caito S., Yang S.R., Megson I.L., Rahman I. Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells. Am J Physiol Lung Cell Mol Physiol 2008, 294:L478-L488.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.294
-
-
Kode, A.1
Rajendrasozhan, S.2
Caito, S.3
Yang, S.R.4
Megson, I.L.5
Rahman, I.6
-
38
-
-
48349144852
-
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span
-
Pearson K.J., Baur J.A., Lewis K.N., Peshkin L., Price N.L., Labinskyy N., Swindell W.R., Kamara D., Minor R.K., Perez E., et al. Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab 2008, 8:157-168.
-
(2008)
Cell Metab
, vol.8
, pp. 157-168
-
-
Pearson, K.J.1
Baur, J.A.2
Lewis, K.N.3
Peshkin, L.4
Price, N.L.5
Labinskyy, N.6
Swindell, W.R.7
Kamara, D.8
Minor, R.K.9
Perez, E.10
-
39
-
-
77953741269
-
Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2
-
Ungvari Z., Bagi Z., Feher A., Recchia F.A., Sonntag W.E., Pearson K., de Cabo R., Csiszar A. Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2. Am J Physiol Heart Circ Physiol 2010, 299:H18-24.
-
(2010)
Am J Physiol Heart Circ Physiol
, vol.299
-
-
Ungvari, Z.1
Bagi, Z.2
Feher, A.3
Recchia, F.A.4
Sonntag, W.E.5
Pearson, K.6
de Cabo, R.7
Csiszar, A.8
-
40
-
-
68149150584
-
Resveratrol improves endothelial function: role of TNF2010 and vascular oxidative stress
-
Zhang H., Zhang J., Ungvari Z., Zhang C. Resveratrol improves endothelial function: role of TNF2010 and vascular oxidative stress. Arterioscler Thromb Vasc Biol 2009, 29:1164-1171.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, pp. 1164-1171
-
-
Zhang, H.1
Zhang, J.2
Ungvari, Z.3
Zhang, C.4
-
41
-
-
77955267856
-
Sofalcone, a gastric mucosa protective agent, increases vascular endothelial growth factor via the Nrf2-heme-oxygenase-1 dependent pathway in gastric epithelial cells
-
Shibuya A., Onda K., Kawahara H., Uchiyama Y., Nakayama H., Omi T., Nagaoka M., Matsui H., Hirano T. Sofalcone, a gastric mucosa protective agent, increases vascular endothelial growth factor via the Nrf2-heme-oxygenase-1 dependent pathway in gastric epithelial cells. Biochem Biophys Res Commun 2010, 398:581-584.
-
(2010)
Biochem Biophys Res Commun
, vol.398
, pp. 581-584
-
-
Shibuya, A.1
Onda, K.2
Kawahara, H.3
Uchiyama, Y.4
Nakayama, H.5
Omi, T.6
Nagaoka, M.7
Matsui, H.8
Hirano, T.9
-
42
-
-
62649093402
-
Sofalcone, an anti-ulcer chalcone derivative, suppresses inflammatory crosstalk between macrophages and adipocytes and adipocyte differentiation: implication of heme-oxygenase-1 induction
-
Tanaka H., Nakamura S., Onda K., Tazaki T., Hirano T. Sofalcone, an anti-ulcer chalcone derivative, suppresses inflammatory crosstalk between macrophages and adipocytes and adipocyte differentiation: implication of heme-oxygenase-1 induction. Biochem Biophys Res Commun 2009, 381:566-571.
-
(2009)
Biochem Biophys Res Commun
, vol.381
, pp. 566-571
-
-
Tanaka, H.1
Nakamura, S.2
Onda, K.3
Tazaki, T.4
Hirano, T.5
-
43
-
-
0036949607
-
Dietary isothiocyanates, glutathione S-transferase polymorphisms and colorectal cancer risk in the Singapore Chinese Health Study
-
Seow A., Yuan J.M., Sun C.L., Van Den Berg D., Lee H.P., Yu M.C. Dietary isothiocyanates, glutathione S-transferase polymorphisms and colorectal cancer risk in the Singapore Chinese Health Study. Carcinogenesis 2002, 23:2055-2061.
-
(2002)
Carcinogenesis
, vol.23
, pp. 2055-2061
-
-
Seow, A.1
Yuan, J.M.2
Sun, C.L.3
Van Den Berg, D.4
Lee, H.P.5
Yu, M.C.6
-
44
-
-
29644443964
-
Identification of sensor cysteines in human Keap1 modified by the cancer chemopreventive agent sulforaphane
-
Hong F., Freeman M.L., Liebler D.C. Identification of sensor cysteines in human Keap1 modified by the cancer chemopreventive agent sulforaphane. Chem Res Toxicol 2005, 18:1917-1926.
-
(2005)
Chem Res Toxicol
, vol.18
, pp. 1917-1926
-
-
Hong, F.1
Freeman, M.L.2
Liebler, D.C.3
-
45
-
-
0346888660
-
Sulforaphane and quercetin modulate PhIP-DNA adduct formation in human HepG2 cells and hepatocytes
-
Bacon J.R., Williamson G., Garner R.C., Lappin G., Langouet S., Bao Y. Sulforaphane and quercetin modulate PhIP-DNA adduct formation in human HepG2 cells and hepatocytes. Carcinogenesis 2003, 24:1903-1911.
-
(2003)
Carcinogenesis
, vol.24
, pp. 1903-1911
-
-
Bacon, J.R.1
Williamson, G.2
Garner, R.C.3
Lappin, G.4
Langouet, S.5
Bao, Y.6
-
46
-
-
33748089664
-
Inhibition of 7,12-dimethylbenz(a)anthracene-induced skin tumorigenesis in C57BL/6 mice by sulforaphane is mediated by nuclear factor E2-related factor 2
-
Xu C., Huang M.T., Shen G., Yuan X., Lin W., Khor T.O., Conney A.H., Kong A.N. Inhibition of 7,12-dimethylbenz(a)anthracene-induced skin tumorigenesis in C57BL/6 mice by sulforaphane is mediated by nuclear factor E2-related factor 2. Cancer Res 2006, 66:8293-8296.
-
(2006)
Cancer Res
, vol.66
, pp. 8293-8296
-
-
Xu, C.1
Huang, M.T.2
Shen, G.3
Yuan, X.4
Lin, W.5
Khor, T.O.6
Conney, A.H.7
Kong, A.N.8
-
47
-
-
4143130097
-
A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase
-
Myzak M.C., Karplus P.A., Chung F.L., Dashwood R.H. A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase. Cancer Res 2004, 64:5767-5774.
-
(2004)
Cancer Res
, vol.64
, pp. 5767-5774
-
-
Myzak, M.C.1
Karplus, P.A.2
Chung, F.L.3
Dashwood, R.H.4
-
48
-
-
33846838750
-
Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects
-
Myzak M.C., Tong P., Dashwood W.M., Dashwood R.H., Ho E. Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects. Exp Biol Med (Maywood) 2007, 232:227-234.
-
(2007)
Exp Biol Med (Maywood)
, vol.232
, pp. 227-234
-
-
Myzak, M.C.1
Tong, P.2
Dashwood, W.M.3
Dashwood, R.H.4
Ho, E.5
-
49
-
-
77954197626
-
A small-molecule inducer of the antioxidant response element
-
Hur W., Sun Z., Jiang T., Mason D.E., Peters E.C., Zhang D.D., Luesch H., Schultz P.G., Gray N.S. A small-molecule inducer of the antioxidant response element. Chem Biol 2010, 17:537-547.
-
(2010)
Chem Biol
, vol.17
, pp. 537-547
-
-
Hur, W.1
Sun, Z.2
Jiang, T.3
Mason, D.E.4
Peters, E.C.5
Zhang, D.D.6
Luesch, H.7
Schultz, P.G.8
Gray, N.S.9
-
50
-
-
33947379500
-
Protective effect of sulforaphane against dopaminergic cell death
-
Han J.M., Lee Y.J., Lee S.Y., Kim E.M., Moon Y., Kim H.W., Hwang O. Protective effect of sulforaphane against dopaminergic cell death. J Pharmacol Exp Ther 2007, 321:249-256.
-
(2007)
J Pharmacol Exp Ther
, vol.321
, pp. 249-256
-
-
Han, J.M.1
Lee, Y.J.2
Lee, S.Y.3
Kim, E.M.4
Moon, Y.5
Kim, H.W.6
Hwang, O.7
-
51
-
-
70350761712
-
Sulforaphane as an inducer of glutathione prevents oxidative stress-induced cell death in a dopaminergic-like neuroblastoma cell line
-
Tarozzi A., Morroni F., Merlicco A., Hrelia S., Angeloni C., Cantelli-Forti G., Hrelia P. Sulforaphane as an inducer of glutathione prevents oxidative stress-induced cell death in a dopaminergic-like neuroblastoma cell line. J Neurochem 2009, 111:1161-1171.
-
(2009)
J Neurochem
, vol.111
, pp. 1161-1171
-
-
Tarozzi, A.1
Morroni, F.2
Merlicco, A.3
Hrelia, S.4
Angeloni, C.5
Cantelli-Forti, G.6
Hrelia, P.7
-
52
-
-
38349014710
-
Induction of the phase II detoxification pathway suppresses neuron loss in Drosophila models of Parkinson's disease
-
Trinh K., Moore K., Wes P.D., Muchowski P.J., Dey J., Andrews L., Pallanck L.J. Induction of the phase II detoxification pathway suppresses neuron loss in Drosophila models of Parkinson's disease. J Neurosci 2008, 28:465-472.
-
(2008)
J Neurosci
, vol.28
, pp. 465-472
-
-
Trinh, K.1
Moore, K.2
Wes, P.D.3
Muchowski, P.J.4
Dey, J.5
Andrews, L.6
Pallanck, L.J.7
-
53
-
-
38949126129
-
15-Deoxy-Delta(12,14)-prostaglandin J2: an electrophilic trigger of cellular responses
-
Uchida K., Shibata T. 15-Deoxy-Delta(12,14)-prostaglandin J2: an electrophilic trigger of cellular responses. Chem Res Toxicol 2008, 21:138-144.
-
(2008)
Chem Res Toxicol
, vol.21
, pp. 138-144
-
-
Uchida, K.1
Shibata, T.2
-
54
-
-
42449119839
-
Accumulation of 15-deoxy-delta(12,14)-prostaglandin J2 adduct formation with Keap1 over time: effects on potency for intracellular antioxidant defence induction
-
Oh J.Y., Giles N., Landar A., Darley-Usmar V. Accumulation of 15-deoxy-delta(12,14)-prostaglandin J2 adduct formation with Keap1 over time: effects on potency for intracellular antioxidant defence induction. Biochem J 2008, 411:297-306.
-
(2008)
Biochem J
, vol.411
, pp. 297-306
-
-
Oh, J.Y.1
Giles, N.2
Landar, A.3
Darley-Usmar, V.4
-
55
-
-
69149085422
-
15-Deoxy-delta 12, 14-prostaglandin J2 induces upregulation of multidrug resistance-associated protein 1 via Nrf2 activation in human breast cancer cells
-
Song N.Y., Kim D.H., Kim E.H., Na H.K., Surh Y.J. 15-Deoxy-delta 12, 14-prostaglandin J2 induces upregulation of multidrug resistance-associated protein 1 via Nrf2 activation in human breast cancer cells. Ann N Y Acad Sci 2009, 1171:210-216.
-
(2009)
Ann N Y Acad Sci
, vol.1171
, pp. 210-216
-
-
Song, N.Y.1
Kim, D.H.2
Kim, E.H.3
Na, H.K.4
Surh, Y.J.5
-
56
-
-
33646591929
-
15d-prostaglandin J2 protects brain from ischemia-reperfusion injury
-
Lin T.N., Cheung W.M., Wu J.S., Chen J.J., Lin H., Chen J.J., Liou J.Y., Shyue S.K., Wu K.K. 15d-prostaglandin J2 protects brain from ischemia-reperfusion injury. Arterioscler Thromb Vasc Biol 2006, 26:481-487.
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 481-487
-
-
Lin, T.N.1
Cheung, W.M.2
Wu, J.S.3
Chen, J.J.4
Lin, H.5
Chen, J.J.6
Liou, J.Y.7
Shyue, S.K.8
Wu, K.K.9
-
57
-
-
10744230015
-
Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-Delta(12,14)-prostaglandin j(2)
-
Itoh K., Mochizuki M., Ishii Y., Ishii T., Shibata T., Kawamoto Y., Kelly V., Sekizawa K., Uchida K., Yamamoto M. Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-Delta(12,14)-prostaglandin j(2). Mol Cell Biol 2004, 24:36-45.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 36-45
-
-
Itoh, K.1
Mochizuki, M.2
Ishii, Y.3
Ishii, T.4
Shibata, T.5
Kawamoto, Y.6
Kelly, V.7
Sekizawa, K.8
Uchida, K.9
Yamamoto, M.10
-
58
-
-
4143081630
-
Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes
-
Nakamura Y., Yoshida C., Murakami A., Ohigashi H., Osawa T., Uchida K. Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes. FEBS Lett 2004, 572:245-250.
-
(2004)
FEBS Lett
, vol.572
, pp. 245-250
-
-
Nakamura, Y.1
Yoshida, C.2
Murakami, A.3
Ohigashi, H.4
Osawa, T.5
Uchida, K.6
-
59
-
-
0036258778
-
Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation accompanied by apoptosis: the alpha,beta-unsaturated carbonyl group is a prerequisite
-
Murakami A., Takahashi D., Kinoshita T., Koshimizu K., Kim H.W., Yoshihiro A., Nakamura Y., Jiwajinda S., Terao J., Ohigashi H. Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation accompanied by apoptosis: the alpha,beta-unsaturated carbonyl group is a prerequisite. Carcinogenesis 2002, 23:795-802.
-
(2002)
Carcinogenesis
, vol.23
, pp. 795-802
-
-
Murakami, A.1
Takahashi, D.2
Kinoshita, T.3
Koshimizu, K.4
Kim, H.W.5
Yoshihiro, A.6
Nakamura, Y.7
Jiwajinda, S.8
Terao, J.9
Ohigashi, H.10
-
60
-
-
69949188413
-
In vitro covalent binding proteins of zerumbone, a chemopreventive food factor
-
Ohnishi K., Irie K., Murakami A. In vitro covalent binding proteins of zerumbone, a chemopreventive food factor. Biosci Biotechnol Biochem 2009, 73:1905-1907.
-
(2009)
Biosci Biotechnol Biochem
, vol.73
, pp. 1905-1907
-
-
Ohnishi, K.1
Irie, K.2
Murakami, A.3
-
61
-
-
77954349448
-
Functionalized aurones as inducers of NAD(P)H:quinone oxidoreductase 1 that activate AhR/XRE and Nrf2/ARE signaling pathways: synthesis, evaluation and SAR
-
Lee C.Y., Chew E.H., Go M.L. Functionalized aurones as inducers of NAD(P)H:quinone oxidoreductase 1 that activate AhR/XRE and Nrf2/ARE signaling pathways: synthesis, evaluation and SAR. Eur J Med Chem 2010, 45:2957-2971.
-
(2010)
Eur J Med Chem
, vol.45
, pp. 2957-2971
-
-
Lee, C.Y.1
Chew, E.H.2
Go, M.L.3
-
62
-
-
61349182661
-
Functionalized 3-benzylidene-indolin-2-ones: inducers of NAD(P)H-quinone oxidoreductase 1 (NQO1) with antiproliferative activity
-
Zhang W., Go M.L. Functionalized 3-benzylidene-indolin-2-ones: inducers of NAD(P)H-quinone oxidoreductase 1 (NQO1) with antiproliferative activity. Bioorg Med Chem 2009, 17:2077-2090.
-
(2009)
Bioorg Med Chem
, vol.17
, pp. 2077-2090
-
-
Zhang, W.1
Go, M.L.2
-
63
-
-
64549130036
-
Fragrant unsaturated aldehydes elicit activation of the Keap1/Nrf2 system leading to the upregulation of thioredoxin expression and protection against oxidative stress
-
Masutani H., Otsuki R., Yamaguchi Y., Takenaka M., Kanoh N., Takatera K., Kunimoto Y., Yodoi J. Fragrant unsaturated aldehydes elicit activation of the Keap1/Nrf2 system leading to the upregulation of thioredoxin expression and protection against oxidative stress. Antioxid Redox Signal 2009, 11:949-962.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 949-962
-
-
Masutani, H.1
Otsuki, R.2
Yamaguchi, Y.3
Takenaka, M.4
Kanoh, N.5
Takatera, K.6
Kunimoto, Y.7
Yodoi, J.8
-
64
-
-
69949104384
-
Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential
-
Shay K.P., Moreau R.F., Smith E.J., Smith A.R., Hagen T.M. Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential. Biochim Biophys Acta 2009, 1790:1149-1160.
-
(2009)
Biochim Biophys Acta
, vol.1790
, pp. 1149-1160
-
-
Shay, K.P.1
Moreau, R.F.2
Smith, E.J.3
Smith, A.R.4
Hagen, T.M.5
-
65
-
-
0031743135
-
Investigations on the pharmacokinetics of alpha-lipoic acid in healthy volunteers
-
Teichert J., Kern J., Tritschler H.J., Ulrich H., Preiss R. Investigations on the pharmacokinetics of alpha-lipoic acid in healthy volunteers. Int J Clin Pharmacol Ther 1998, 36:625-628.
-
(1998)
Int J Clin Pharmacol Ther
, vol.36
, pp. 625-628
-
-
Teichert, J.1
Kern, J.2
Tritschler, H.J.3
Ulrich, H.4
Preiss, R.5
-
66
-
-
54049130826
-
Control of cellular redox status and upregulation of quinone reductase NQO1 via Nrf2 activation by alpha-lipoic acid in human leukemia HL-60 cells
-
Elangovan S., Hsieh T.C. Control of cellular redox status and upregulation of quinone reductase NQO1 via Nrf2 activation by alpha-lipoic acid in human leukemia HL-60 cells. Int J Oncol 2008, 33:833-838.
-
(2008)
Int J Oncol
, vol.33
, pp. 833-838
-
-
Elangovan, S.1
Hsieh, T.C.2
-
67
-
-
1542723493
-
Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid
-
Suh J.H., Shenvi S.V., Dixon B.M., Liu H., Jaiswal A.K., Liu R.M., Hagen T.M. Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid. Proc Natl Acad Sci U S A 2004, 101:3381-3386.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 3381-3386
-
-
Suh, J.H.1
Shenvi, S.V.2
Dixon, B.M.3
Liu, H.4
Jaiswal, A.K.5
Liu, R.M.6
Hagen, T.M.7
-
68
-
-
0037342554
-
The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice
-
Farr S.A., Poon H.F., Dogrukol-Ak D., Drake J., Banks W.A., Eyerman E., Butterfield D.A., Morley J.E. The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice. J Neurochem 2003, 84:1173-1183.
-
(2003)
J Neurochem
, vol.84
, pp. 1173-1183
-
-
Farr, S.A.1
Poon, H.F.2
Dogrukol-Ak, D.3
Drake, J.4
Banks, W.A.5
Eyerman, E.6
Butterfield, D.A.7
Morley, J.E.8
-
69
-
-
33845442944
-
Chronic dietary alpha-lipoic acid reduces deficits in hippocampal memory of aged Tg2576 mice
-
Quinn J.F., Bussiere J.R., Hammond R.S., Montine T.J., Henson E., Jones R.E., Stackman R.W. Chronic dietary alpha-lipoic acid reduces deficits in hippocampal memory of aged Tg2576 mice. Neurobiol Aging 2007, 28:213-225.
-
(2007)
Neurobiol Aging
, vol.28
, pp. 213-225
-
-
Quinn, J.F.1
Bussiere, J.R.2
Hammond, R.S.3
Montine, T.J.4
Henson, E.5
Jones, R.E.6
Stackman, R.W.7
-
70
-
-
56249128623
-
Dithiolethiones for cancer chemoprevention: where do we stand?
-
Zhang Y., Munday R. Dithiolethiones for cancer chemoprevention: where do we stand?. Mol Cancer Ther 2008, 7:3470-3479.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 3470-3479
-
-
Zhang, Y.1
Munday, R.2
-
71
-
-
0028178821
-
Regulation of phase 2 enzyme induction by oltipraz and other dithiolethiones
-
Egner P.A., Kensler T.W., Prestera T., Talalay P., Libby A.H., Joyner H.H., Curphey T.J. Regulation of phase 2 enzyme induction by oltipraz and other dithiolethiones. Carcinogenesis 1994, 15:177-181.
-
(1994)
Carcinogenesis
, vol.15
, pp. 177-181
-
-
Egner, P.A.1
Kensler, T.W.2
Prestera, T.3
Talalay, P.4
Libby, A.H.5
Joyner, H.H.6
Curphey, T.J.7
-
72
-
-
60349128328
-
Comparison of citrus coumarins on carcinogen-detoxifying enzymes in Nrf2 knockout mice
-
Prince M., Li Y., Childers A., Itoh K., Yamamoto M., Kleiner H.E. Comparison of citrus coumarins on carcinogen-detoxifying enzymes in Nrf2 knockout mice. Toxicol Lett 2009, 185:180-186.
-
(2009)
Toxicol Lett
, vol.185
, pp. 180-186
-
-
Prince, M.1
Li, Y.2
Childers, A.3
Itoh, K.4
Yamamoto, M.5
Kleiner, H.E.6
-
73
-
-
0041341933
-
Oltipraz is a bifunctional inducer activating both phase I and phase II drug-metabolizing enzymes via the xenobiotic responsive element
-
Miao W., Hu L., Kandouz M., Batist G. Oltipraz is a bifunctional inducer activating both phase I and phase II drug-metabolizing enzymes via the xenobiotic responsive element. Mol Pharmacol 2003, 64:346-354.
-
(2003)
Mol Pharmacol
, vol.64
, pp. 346-354
-
-
Miao, W.1
Hu, L.2
Kandouz, M.3
Batist, G.4
-
74
-
-
20144388741
-
Safety and efficacy of weekly oral oltipraz in chronic smokers
-
Kelley M.J., Glaser E.M., Herndon J.E., Becker F., Bhagat R., Zhang Y.J., Santella R.M., Carmella S.G., Hecht S.S., Gallot L., et al. Safety and efficacy of weekly oral oltipraz in chronic smokers. Cancer Epidemiol Biomarkers Prev 2005, 14:892-899.
-
(2005)
Cancer Epidemiol Biomarkers Prev
, vol.14
, pp. 892-899
-
-
Kelley, M.J.1
Glaser, E.M.2
Herndon, J.E.3
Becker, F.4
Bhagat, R.5
Zhang, Y.J.6
Santella, R.M.7
Carmella, S.G.8
Hecht, S.S.9
Gallot, L.10
-
75
-
-
33747339232
-
Oltipraz chemoprevention trial in Qidong, People's Republic of China: unaltered oxidative biomarkers
-
Glintborg B., Weimann A., Kensler T.W., Poulsen H.E. Oltipraz chemoprevention trial in Qidong, People's Republic of China: unaltered oxidative biomarkers. Free Radic Biol Med 2006, 41:1010-1014.
-
(2006)
Free Radic Biol Med
, vol.41
, pp. 1010-1014
-
-
Glintborg, B.1
Weimann, A.2
Kensler, T.W.3
Poulsen, H.E.4
-
76
-
-
24744453945
-
Specific patterns of electrophile adduction trigger Keap1 ubiquitination and Nrf2 activation
-
Hong F., Sekhar K.R., Freeman M.L., Liebler D.C. Specific patterns of electrophile adduction trigger Keap1 ubiquitination and Nrf2 activation. J Biol Chem 2005, 280:31768-31775.
-
(2005)
J Biol Chem
, vol.280
, pp. 31768-31775
-
-
Hong, F.1
Sekhar, K.R.2
Freeman, M.L.3
Liebler, D.C.4
-
77
-
-
0028945134
-
Vascular smooth muscle cell heme oxygenases generate guanylyl cyclase-stimulatory carbon monoxide
-
Christodoulides N., Durante W., Kroll M.H., Schafer A.I. Vascular smooth muscle cell heme oxygenases generate guanylyl cyclase-stimulatory carbon monoxide. Circulation 1995, 91:2306-2309.
-
(1995)
Circulation
, vol.91
, pp. 2306-2309
-
-
Christodoulides, N.1
Durante, W.2
Kroll, M.H.3
Schafer, A.I.4
-
78
-
-
67650514338
-
Biological responses to arsenic compounds
-
Platanias L.C. Biological responses to arsenic compounds. J Biol Chem 2009, 284:18583-18587.
-
(2009)
J Biol Chem
, vol.284
, pp. 18583-18587
-
-
Platanias, L.C.1
-
79
-
-
67649752330
-
Reactive oxygen species are not required for an arsenic trioxide-induced antioxidant response or apoptosis
-
Morales A.A., Gutman D., Cejas P.J., Lee K.P., Boise L.H. Reactive oxygen species are not required for an arsenic trioxide-induced antioxidant response or apoptosis. J Biol Chem 2009, 284:12886-12895.
-
(2009)
J Biol Chem
, vol.284
, pp. 12886-12895
-
-
Morales, A.A.1
Gutman, D.2
Cejas, P.J.3
Lee, K.P.4
Boise, L.H.5
-
80
-
-
73149120045
-
NRF2 cysteine residues are critical for oxidant/electrophile-sensing, Kelch-like ECH-associated protein-1-dependent ubiquitination-proteasomal degradation, and transcription activation
-
He X., Ma Q. NRF2 cysteine residues are critical for oxidant/electrophile-sensing, Kelch-like ECH-associated protein-1-dependent ubiquitination-proteasomal degradation, and transcription activation. Mol Pharmacol 2009, 76:1265-1278.
-
(2009)
Mol Pharmacol
, vol.76
, pp. 1265-1278
-
-
He, X.1
Ma, Q.2
-
81
-
-
73949112805
-
Critical cysteine residues of Kelch-like ECH-associated protein 1 in arsenic sensing and suppression of nuclear factor erythroid 2-related factor 2
-
He X., Ma Q. Critical cysteine residues of Kelch-like ECH-associated protein 1 in arsenic sensing and suppression of nuclear factor erythroid 2-related factor 2. J Pharmacol Exp Ther 2010, 332:66-75.
-
(2010)
J Pharmacol Exp Ther
, vol.332
, pp. 66-75
-
-
He, X.1
Ma, Q.2
|