Curcumin induces heme oxygenase 1 through generation of reactive oxygen species, p38 activation and phosphatase inhibition

International Journal of Molecular Medicine

Volumn 19, Issue 1, 2007, Pages 165-172

  McNally, Stephen J ^a   Harrison, Ewen M ^a   Ross, James A ^a   Garden, O James ^a   Wigmore, Stephen J ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Curcumin; Heme oxygenase 1; Hepatocyte

Indexed keywords

ANTIOXIDANT; CASPASE 3; CASPASE 7; CURCUMIN; HEME OXYGENASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; NFE2L2 PROTEIN, HUMAN; PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN KINASE C; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2;

ARTICLE; BIOLOGICAL MODEL; CELL LINE; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; LIVER CELL; METABOLISM; MITOCHONDRION; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANTIOXIDANTS; CASPASE 3; CASPASE 7; CELL LINE; CURCUMIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ANTAGONISM; HEME OXYGENASE-1; HEPATOCYTES; HUMANS; MITOCHONDRIA; MODELS, BIOLOGICAL; NF-E2-RELATED FACTOR 2; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN KINASE C; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 34147165621     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.19.1.165     Document Type: Article

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