Carnosic acid protects neuronal HT22 Cells through activation of the antioxidant-responsive element in free carboxylic acid- and catechol hydroxyl moieties-dependent manners

Neuroscience Letters

Volumn 434, Issue 3, 2008, Pages 260-265

  Satoh, Takumi ^a   Izumi, Masanori ^a   Inukai, Yuki ^a   Tsutsumi, Yasutaka ^a   Nakayama, Naoto ^a   Kosaka, Kunio ^b   Shimojo, Yosuke ^b   Kitajima, Chieko ^b   Itoh, Ken ^c   Yokoi, Toshio ^d   Shirasawa, Takuji ^e  

^a IWATE UNIVERSITY   (Japan)

^b Osaka City University Medical School   (Japan)

^c HIROSAKI UNIVERSITY   (Japan)

^d KOBE GAKUIN UNIVERSITY   (Japan)

^e TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

Author keywords

Carnosic acid; Carnosol; Electrophilic compounds; HT22 cells; Keap1; Nrf2

Indexed keywords

CARBONIC ACID; CARNOSIC ACID; CARNOSOL; GAMMA GLUTAMYL CYSTEINE LIGASE; GLUTAMIC ACID; HEMEOXYGENASE 1; LIGASE; OXIDOREDUCTASE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; ELECTROPHILIC STRESS; ESTERIFICATION; HUMAN; HUMAN CELL; NERVE CELL; NEUROPROTECTION; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIOXIDANTS; CARBOXYLIC ACIDS; CATECHOLS; CELL LINE; CYTOPROTECTION; CYTOSKELETAL PROTEINS; DITERPENES, ABIETANE; DRUG EVALUATION, PRECLINICAL; ESTERASES; GENE EXPRESSION REGULATION; GLUTATHIONE; HYDROXYL RADICAL; MEMBRANE LIPIDS; MICE; MOLECULAR STRUCTURE; NEURONS; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; OXIDATION-REDUCTION; OXIDATIVE STRESS; PHENANTHRENES; PLANT EXTRACTS; RESPONSE ELEMENTS; STEROIDS;

EID: 40849145272     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2008.01.079     Document Type: Article

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