Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation accompanied by apoptosis: The α,β-unsaturated carbonyl group is a prerequisite

Carcinogenesis

Volumn 23, Issue 5, 2002, Pages 795-802

  Murakami, Akira ^a   Takahashi, Daisuke ^a   Kinoshita, Takashi ^a   Koshimizu, Koichi ^a   Kim, Ha Won ^b   Yoshihiro, Akira ^b   Nakamura, Yoshimasa ^e   Jiwajinda, Suratwadee ^c   Terao, Junji ^d   Ohigashi, Hajime ^b  

^a KINKI UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c KASETSART UNIVERSITY   (Thailand)

^d UNIVERSITY OF TOKUSHIMA   (Japan)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

CARBONYL DERIVATIVE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYSTEINE; CYTOCHROME C; CYTOKINE; DIMETHYL SULFOXIDE; GAMMA INTERFERON; GINGER EXTRACT; GLUTATHIONE TRANSFERASE; HEAT SHOCK PROTEIN; HUMULENE; I KAPPA B KINASE; LIPOCORTIN 5; LIPOPOLYSACCHARIDE; NITRIC OXIDE SYNTHASE; NITRITE; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDYLSERINE; PROSTAGLANDIN E2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SESQUITERPENE; SESQUITERPENE DERIVATIVE; SESQUITERPENOID; SOMATOMEDIN; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UNINDEXED DRUG; XANTHINE OXIDASE; ZERUMBONE;

ALPHA CHAIN; ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; BETA CHAIN; CARCINOGENESIS; CELL COUNT; CELL CULTURE; CELL GROWTH; CELL PROLIFERATION; CHEMOPROPHYLAXIS; CHROMATIN CONDENSATION; COLON ADENOCARCINOMA; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE RELEASE; DRUG STRUCTURE; ENZYME INDUCTION; FIBROBLAST; GINGER; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MACROPHAGE; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; SOUTHEAST ASIA; STRUCTURE ACTIVITY RELATION;

ADENOCARCINOMA; ANIMALS; ANTICARCINOGENIC AGENTS; APOPTOSIS; CELL DIVISION; COLONIC NEOPLASMS; CYCLOOXYGENASE 2; FREE RADICALS; HUMANS; ISOENZYMES; MEMBRANE PROTEINS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; SESQUITERPENES; SUPEROXIDES; TETRADECANOYLPHORBOL ACETATE; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036258778     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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