Elevated gadd153/chop expression and enhanced c-Jun N-terminal protein kinase activation sensitizes aged cells to ER stress

Experimental Gerontology

Volumn 39, Issue 5, 2004, Pages 735-744

  Li, Ji ^a   Holbrook, Nikki J ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Apoptosis; ER stress; gadd153 chop; Hepatocytes; JNK MAP kinase

Indexed keywords

PROTEIN; STRESS ACTIVATED PROTEIN KINASE; THAPSIGARGIN; TUNICAMYCIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL AGING; CELL DEATH; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; GADD153 GENE; GENE; GENE EXPRESSION; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

AGING; ANIMALS; APOPTOSIS; CCAAT-ENHANCER-BINDING PROTEINS; CELLS, CULTURED; ENDOPLASMIC RETICULUM; ENZYME INHIBITORS; GENE EXPRESSION; GLYCOSYLATION; HEPATOCYTES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; RATS, INBRED F344; THAPSIGARGIN; TRANSCRIPTION FACTOR CHOP; TRANSCRIPTION FACTORS; TUNICAMYCIN;

EID: 2342627368     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exger.2004.02.008     Document Type: Article

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