4-Anilinoquinoline triazines: A novel class of hybrid antimalarial agents

European Journal of Medicinal Chemistry

Volumn 46, Issue 2, 2011, Pages 676-690

  Kumar, Ashok ^a   Srivastava, Kumkum ^a   Raja Kumar, S ^a   Siddiqi, M I ^a   Puri, Sunil K ^a   Sexana, Jitendra K ^a   Chauhan, Prem M S ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

4 anilinoquinoline triazine; Antimalarial; P. falciparum; P. yoelii

Indexed keywords

4 ANILINOQUINOLINE TRIAZINE DERIVATIVE; ANTIMALARIAL AGENT; N (7 CHLORO QUINOLIN 4 YL) N' [4 (4 ETHYL PIPERAZIN 1 YL) 6 PIPERIDIN 1 YL [1,3,5]TRIAZIN 2 YL] BENZENE 1,4 DIAMINE; N (7 CHLORO QUINOLIN 4 YL) N' [4 (4 METHYL PIPERAZIN 1 YL) 6 PIPERIDIN 1 YL [1,3,5]TRIAZIN 2 YL] BENZENE 1,4 DIAMINE; N [4 (7 CHLORO QUINOLIN 4 YLAMINO) PHENYL] 6 (4 ETHYL PIPERAZIN 1 YL) N' PHENYL [1,3,5]TRIAZINE 2,4 DIAMINE; N [4 (7 CHLORO QUINOLIN 4 YLAMINO) PHENYL] 6 (4 ETHYLPIPERAZIN 1 YL) N' O TOLYL [1,3,5]TRIAZINE 2,4 DIAMINE; N [4 (7 CHLORO QUINOLIN 4 YLAMINO) PHENYL] 6 (4 METHYL PIPERAZIN 1 YL) N' PHENYL [1,3,5]TRIAZINE 2,4 DIAMINE; N [4 (7 CHLORO QUINOLIN 4 YLAMINO) PHENYL] N' (2 DIETHYLAMINO ETHYL) 6 PIPERIDIN 1 YL [1,3,5]TRIAZINE 2,4 DIAMINE; N [4 (7 CHLORO QUINOLIN 4 YLAMINO) PHENYL] N' (2 DIETHYLAMINO ETHYL) N' PHENYL [1,3,5]TRIAZINE 2,4,6 TRIAMINE; N [4 (7 CHLORO QUINOLIN 4 YLAMINO) PHENYL] N' (2 DIETHYLAMINO ETHYL) N'O TOLYL [1,3,5]TRIAZINE 2,4,6 TRIAMINE; N [4 (7 CHLORO QUINOLIN 4 YLAMINO) PHENYL] N' (3 MORPHOLIN 4 YL PROPYL) 6 PIPERIDIN 1 YL [1,3,5]TRIAZINE 2,4 DIAMINE; N [4 (7 CHLORO QUINOLIN 4 YLAMINO) PHENYL] N' (3 MORPHOLIN 4 YL PROPYL) N' O TOLYL [1,3,5]TRIAZINE 2,4,6 TRIAMINE; N [4 (7 CHLORO QUINOLIN 4 YLAMINO) PHENYL] N' (3 MORPHOLIN 4 YL PROPYL) N' P TOLYL [1,3,5]TRIAZINE 2,4,6 TRIAMINE; N [4 (7 CHLORO QUINOLIN 4 YLAMINO) PHENYL] N' (3 MORPHOLIN 4 YL PROPYL) N' PHENYL [1,3,5]TRIAZINE 2,4,6 TRIAMINE; N [4 (7 CHLORO QUINOLIN 4 YLAMINO) PHENYL] N' CYCLOHEXYL 6 PIPERIDIN 1 YL [1,3,5]TRIAZINE 2,4 DIAMINE; N [4 (7 CHLORO QUINOLIN 4 YLAMINO) PHENYL] N' CYCLOHEXYL N' O TOLYL [1,3,5]TRIAZINE 2,4,6 TRIAMINE; N [4 (7 CHLORO QUINOLIN 4 YLAMINO) PHENYL] N' CYCLOHEXYL N' PHENYL [1,3,5]TRIAZINE 2,4,6 TRIAMINE; N [4 (7 CHLORO QUINOLIN 4 YLAMINO) PHENYL] N' METHYL N' O TOLYL [1,3,5]TRIAZINE 2,4,6 TRIAMINE; N [4 (7 CHLORO QUINOLIN 4 YLAMINO) PHENYL] N' METHYL N' P TOLYL [1,3,5]TRIAZINE 2,4,6 TRIAMINE; N [4 (7 CHLORO QUINOLIN 4 YLAMINO) PHENYL] N' METHYL N' PHENYL [1,3,5]TRIAZINE 2,4,6 TRIAMINE; N [4 (7 CHLORO QUINOLIN 4 YLAMINO) PHENYL] N' O TOLYL [1,3,5]TRIAZINE 2,4,6 TRIAMINE; N [4 (7 CHLORO QUINOLIN 4 YLAMINO) PHENYL] N' PHENYL [1,3,5]TRIAZINE 2,4,6 TRIAMINE; N BENZYL N' [4 (7 CHLORO QUINOLIN 4 YLAMINO) PHENYL] 6 PIPERIDIN 1 YL [1,3,5]TRIAZINE 2,4 DIAMINE; N BENZYL N' [4 (7 CHLORO QUINOLIN 4 YLAMINO) PHENYL] N' O TOLYL [1,3,5]TRIAZINE 2,4,6 TRIAMINE; N BENZYL N' [4 (7 CHLORO QUINOLIN 4 YLAMINO) PHENYL] N' PHENYL [1,3,5]TRIAZINE 2,4,6 TRIAMINE; N BUTYL N' [4 (7 CHLORO QUINOLIN 4 YLAMINO) PHENYL] N' O TOLYL [1,3,5]TRIAZINE 2,4,6 TRIAMINE; N BUTYL N' [4 (7 CHLORO QUINOLIN 4 YLAMINO) PHENYL] N' PHENYL [1,3,5]TRIAZINE 2,4,6 TRIAMINE; N[4 (7 CHLORO QUINOLIN 4 YLAMINO) PHENYL] 6 (4 METHYL PIPERAZIN1 YL) N' O TOLYL [1,3,5]TRIAZINE 2,4 DIAMINE; TRIAZINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG INHIBITION; DRUG MECHANISM; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; IN VITRO STUDY; MOLECULAR DOCKING; MOUSE; NONHUMAN; PLASMODIUM FALCIPARUM; PLASMODIUM YOELII;

ANIMALS; ANTIMALARIALS; CELL PROLIFERATION; CERCOPITHECUS AETHIOPS; HEMEPROTEINS; MALARIA; MICE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; QUINOLINES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZINES; VERO CELLS;

EID: 79151479212     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.12.003     Document Type: Article

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