Combining 4-aminoquinoline- and clotrimazole-based pharmacophores toward innovative and potent hybrid antimalarials.

Journal of medicinal chemistry

Volumn 52, Issue 2, 2009, Pages 502-513

  Gemma, Sandra ^a   Campiani, Giuseppe ^a   Butini, Stefania ^a   Joshi, Bhupendra P ^a   Kukreja, Gagan ^a   Coccone, Salvatore Sanna ^a   Bernetti, Matteo ^a   Persico, Marco ^a   Nacci, Vito ^a   Fiorini, Isabella ^a   Novellino, Ettore ^a   Taramelli, Donatella ^a   Basilico, Nicoletta ^a   Parapini, Silvia ^a   Yardley, Vanessa ^a   Croft, Simon ^a   Keller Maerki, Sonja ^a   Rottmann, Matthias ^a   Brun, Reto ^a   Coletta, Massimiliano ^a   Marini, Stefano ^a   Guiso, Giovanna ^a   Caccia, Silvio ^a   Fattorusso, Caterina ^a   more..

^a UNIVERSITY OF SIENA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOQUINOLINE; 4-AMINOQUINOLINE; AMINOQUINOLINE DERIVATIVE; ANTIMALARIAL AGENT; CLOTRIMAZOLE;

ANIMAL; ARTICLE; CELL LINE; CHEMISTRY; DRUG EFFECT; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; MOUSE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLASMODIUM; RAT; SPECIES DIFFERENCE; SYNTHESIS;

AMINOQUINOLINES; ANIMALS; ANTIMALARIALS; CELL LINE; CLOTRIMAZOLE; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; PLASMODIUM; RATS; SPECIES SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 60549091778     PISSN: None     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm801352s     Document Type: Article

References (0)