A novel artemisinin-quinine hybrid with potent antimalarial activity

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 13, 2007, Pages 3599-3602

  Walsh, John J ^a   Coughlan, David ^a   Heneghan, Nicola ^a   Gaynor, Caroline ^a   Bell, Angus ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Artemisinin; Combination chemotherapy; Malaria; Plasmodium falciparum; Quinine; Resistance

Indexed keywords

ANTIMALARIAL AGENT; ARTEMISININ; ARTEMISININ PLUS QUININE; CARBOXYLIC ACID DERIVATIVE; ESTER; QUININE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG ACTIVITY; DRUG POTENCY; DRUG STRUCTURE; MOLECULE; NONHUMAN; PLASMODIUM FALCIPARUM; PROTOZOON;

ANIMALS; ANTIMALARIALS; ARTEMISININS; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; INHIBITORY CONCENTRATION 50; MODELS, CHEMICAL; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; QUININE; TIME FACTORS;

PLASMODIUM FALCIPARUM;

EID: 34250195398     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.04.054     Document Type: Article

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