Trioxaferroquines as new hybrid antimalarial drugs

Journal of Medicinal Chemistry

Volumn 53, Issue 10, 2010, Pages 4103-4109

  Bellot, François ^a   Coslédan, Frédéric ^b   Vendier, Laure ^a   Brocard, Jacques ^c   Meunier, Bernard ^b   Robert, Anne ^a  

^a LCC LABORATOIRE DE CHIMIE DE COORDINATION   (France)

^b Palumed   (France)

^c UNIV LILLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,4 TRIOXANE DERIVATIVE; ANTIMALARIAL AGENT; ARTEMISININ; CHLOROQUINE; QUINOLINE DERIVATIVE; TRIOXAFERROCENE; TRIOXAFERROQUINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIMALARIAL ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PLASMODIUM; PLASMODIUM FALCIPARUM; PLASMODIUM VINCKEI INFECTION; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY CRYSTALLOGRAPHY;

AMINOQUINOLINES; ANIMALS; ANTIMALARIALS; CRYSTALLOGRAPHY, X-RAY; DRUG RESISTANCE; DRUG STABILITY; FEMALE; FERROUS COMPOUNDS; HETEROCYCLIC COMPOUNDS; HUMANS; MALARIA; MICE; MODELS, MOLECULAR; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77952698982     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm100117e     Document Type: Article

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