A prodrug form of a Plasmodium falciparum glutathione reductase inhibitor conjugated with a 4-anilinoquinoline

Journal of Medicinal Chemistry

Volumn 44, Issue 24, 2001, Pages 4268-4276

  Davioud Charvet, E ^a,b   Delarue, S ^a   Biot, C ^a   Schwobel B ^c   Boehme, C C ^c,d   Mussigbrodt A ^d   Maes, L ^e   Sergheraert, C ^a   Grellier, P ^f   Schirmer, R H ^d   Becker, K ^c  

^a INSTITUT PASTEUR DE LILLE   (France)

^b UNIVERSITY OF MICHIGAN   (United States)

^c JUSTUS LIEBIG UNIVERSITY   (Germany)

^d UNIVERSITY OF HEIDELBERG   (Germany)

^e Virco BVBA   (Belgium)

^f MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

4 ANILINOQUINOLINE; CHLOROQUINE; GLUTATHIONE REDUCTASE; GLUTATHIONE REDUCTASE INHIBITOR; GLUTATHIONE TRANSFERASE; PRODRUG; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG CONJUGATION; ENZYME ACTIVITY; GROWTH INHIBITION; HUMAN; HUMAN CELL; MALARIA; PLASMODIUM FALCIPARUM; SURVIVAL TIME;

ANILINE COMPOUNDS; ANIMALS; ANTIMALARIALS; CELL LINE; CHLOROQUINE; DRUG RESISTANCE; ENZYME INHIBITORS; ESTERS; GLUTATHIONE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; HUMANS; MALARIA; MICE; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; PRODRUGS; QUINOLINES;

EID: 0035935690     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010268g     Document Type: Article

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